2K79B

Solution structure of the binary complex between the sh3 and sh2 domain of interleukin-2 tyrosine kinase
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
108
structure length
108
Chain Sequence
NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Proline Isomerization Preorganizes the Itk SH2 Domain for Binding to the Itk SH3 Domain
doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords SH3 domain of Tyrosine-protein kinase ITK/TSK
total genus 11
structure length 108
sequence length 108
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2008-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2k79B00
1FMKA 1TCEA 3EAZA 3OVEA 5EG3B 1A81A 3VRQA 1OPKA 1FU5A 3BUXB 4X6SA 5AULA 1JU5A 1NZLA 1O4GA 4WWQA 1K9AA 1AOUF 4U1PA 1O4NA 2CS0A 1A1EA 1IJRA 1CWEA 3VS4A 2LQNA 1B47A 3VROA 4ROJA 2RORA 1SKJA 2B3OA 2IUGA 1O4BA 1D4WA 4GPLB 5DC0B 1BG1A 5HKYA 4E93A 3EACA 4K2RA 5IBMA 1A09A 1BHHA 1AYCA 2CBLA 1FYRA 1RJAA 2MQIA 3OV1A 1SHDA 3MXYA 2L3TA 2BBUA 4OHIA 3VGOA 3CBLA 4H1OA 1XA6A 2ECDA 3BKBA 3KFJA 1IS0A 4XZ1A 4OHLA 3VRZA 3ZNIA 3HIZB 4QSYA 1X0NA 2CRHA 2K7AB 1O42A 4DGXA 2DCRA 5EHRA 1FU6A 4EIHA 5IBSA 2KK6A 4NWGA 4P9ZA 2JYQA 1GHUA 1LKKA 1O44A 2MC1A 1O4RA 2LQWA 2MRKA 1BFJA 2C0OA 2RMXA 4K44A 1CSZA 1KSWA 3N84A 3NHNA 3VRNA 4M4ZA 3VS0A 1O4LA 1QADA 2FO0A 4LUDA 2AUGA 3S8NA 2Y3AB 4GWFA 2SHPA 2PNAA 1BFIA 3WA4A 3IMDA 2KNOA 4H34A 4GL9E 5EEQA 1AB2A 4L1BB 1BHHB 1O41A 3HHMB 1MW4A 3BUOB 4D8KA 2HDXA 1AYDA 3TKZA 1R1SA 1BLKA 3VS2A 5DC4A 3MXCA 1Y57A 2AOBA 1CJ1A 2EYZA 1O48A 1LCKA 1OO3A 2Y1MA 1Z3KA 1WQUA 2YU7A 1X27A 2IUHA 1H9OA 1BF5A 1HCSB 1P13A 1AD5A 2EYVA 2PTKA 1NZVA 5EELA 2C0IA 2LCTA 3IN7A 2EYYA 3T04A 5EHPA 1NRVA 3IN8A 5D0JA 5HKZA 2EKXA 4FL3A 1O4MA 1LKLA 1M27A 1SPSA 1SHAA 1O47A 2EOBA 4FL2A 1O49A 1JYQA 2K79B 2GSBA 1O4PA 1KA7A 1O4DA 1BKLA 1JYUA 1O4JA 2PLEA 2SRCA 3C7IA 3HCKA 1YVHA 2OZOA 3UF4A 3OB1B 1AYAA 2YSXA 1R1QA 3VS1A 1LUKA 1LCJA 3S8LA 2MRJA 3CXLA 2C0TA 2DM0A 5DF6A 2C9WA 2CI8A 4F5BA 2ETZA 3OB2B 2DLYA 4EY0A 2DLZA 3M7FA 2OQ1A 4K45A 3PQZA 1AYBA 1JYRA 1FHSA 1OPLA 1F2FA 1O4OA 2Y1NA 3MAZA 4LUEA 3N7YA 3CD3A 1O4QA 3IMJA 1O4IA 3GXXA 4TZIA 4JGHA 2AOAA 3QWYA 1A1CA 2PLDA 1YVLA 2L4KA 1O46A 4DGPA 3VRRA 2LNXA 3PSKA 1F1WA 5KAZA 4OHHA 3TL0A 1RPYA 1SHBA 4OHDA 1G83A 1HCTB 2CI9A 4NWFA 1QG1E 3CWGA 4A4CA 1KC2A 3BUMB 3QWXX 1CWDL 2HDVA 2EU0A 1MILA 4F5AA 3K2MA 1GRIA 1KA6A 2RVFA 1D1ZA 1RQQC 1O4HA 1PICA 1ZFPE 5HKWA 3PS5A 1O4EA 5GJIA 1A08A 4U17A 3PFVA 3VRYA 1BLJA 1O4CA 1TZEE 3VS7A 1R1PA 3PLFB 4F59A 1O4FA 2IUIA 4OHEA 2VIFA 1SPRA 2DVJA 3S9KA 2CR4A 1A1AA 1QCFA 4XZ0A 4A4BA 5GJHA 2H8HA 5I6VA 4JE4A 1BMBA 1A07A 3OP0A 2GE9A 1FBVA 3GXWA 1O43A 1BHFA 3VS5A 1X6CA 1OO4A 1O4AA 2EL8A 1O4KA 1I3ZA 3BUNB 1UUSA 2EO3A 2HUWA 1LUMA 1CSYA 5BO4A 3VRPA 4FBNA 2ABLA 1LUIA 3VS3A 2IZVA 4P9VA 4K11A 2H5KA 3UYOA 2DX0A 2FCIA 5AXIA 2RSYA 5CDWA 1A1BA 3PJPA 2CIAA 2LNWA 2PNBA 1LUNA 1BM2A 1D4TA 4JEGA 1AOTF 2H46E 1M61A 3S8OA 1UURA 5DC9A 3GQIB 3VS6A 5J3XA 2L6KA 2EO6A 2QMSA 2MK2A 3BUWB 3PSJA 2HCKA 3N8MA 3US4A 1O45A 1BKMA 1FBZA 1Y1UA 2HMHA 1JWOA 2XP1A 4E68A
chains in the Genus database with same CATH superfamily
1FMKA 1TCEA 3EAZA 3OVEA 5EG3B 1A81A 3VRQA 1OPKA 1FU5A 3BUXB 4X6SA 5AULA 1JU5A 1NZLA 1O4GA 4WWQA 1K9AA 1AOUF 4U1PA 1O4NA 2CS0A 1A1EA 1IJRA 1CWEA 3VS4A 2LQNA 1B47A 3VROA 4ROJA 2RORA 1SKJA 2B3OA 2IUGA 1O4BA 1D4WA 4GPLB 5DC0B 1BG1A 5HKYA 4E93A 3EACA 4K2RA 5IBMA 1A09A 1BHHA 1AYCA 2CBLA 1FYRA 1RJAA 2MQIA 3OV1A 1SHDA 3MXYA 2L3TA 2BBUA 4OHIA 3VGOA 3CBLA 4H1OA 1XA6A 2ECDA 3BKBA 3KFJA 1IS0A 4XZ1A 4OHLA 3VRZA 3ZNIA 3HIZB 4QSYA 1X0NA 2CRHA 2K7AB 1O42A 4DGXA 2DCRA 5EHRA 1FU6A 4EIHA 5IBSA 2KK6A 4NWGA 4P9ZA 2JYQA 1GHUA 1LKKA 1O44A 2MC1A 1O4RA 2LQWA 2MRKA 1BFJA 2C0OA 2RMXA 4K44A 1CSZA 1KSWA 3N84A 3NHNA 3VRNA 4M4ZA 3VS0A 1O4LA 1QADA 2FO0A 4LUDA 2AUGA 3S8NA 2Y3AB 4GWFA 2SHPA 2PNAA 1BFIA 3WA4A 3IMDA 2KNOA 4H34A 4GL9E 5EEQA 1AB2A 4L1BB 1BHHB 1O41A 3HHMB 1MW4A 3BUOB 4D8KA 2HDXA 1AYDA 3TKZA 1R1SA 1BLKA 3VS2A 5DC4A 3MXCA 1Y57A 2AOBA 1CJ1A 2EYZA 1O48A 1LCKA 1OO3A 2Y1MA 1Z3KA 1WQUA 2YU7A 2LRAA 1X27A 2IUHA 1H9OA 1BF5A 1HCSB 1P13A 1AD5A 2EYVA 2PTKA 1NZVA 5EELA 2C0IA 2LCTA 3IN7A 2EYYA 3T04A 5EHPA 1NRVA 3IN8A 5D0JA 5HKZA 2EKXA 4FL3A 1O4MA 1LKLA 1M27A 1SPSA 1SHAA 1O47A 2EOBA 4FL2A 1O49A 1JYQA 2K79B 2GSBA 1O4PA 1KA7A 1O4DA 1BKLA 1JYUA 1O4JA 2PLEA 2SRCA 3C7IA 3HCKA 1YVHA 2OZOA 3UF4A 3OB1B 1AYAA 2YSXA 1R1QA 3VS1A 1LUKA 1LCJA 3S8LA 2MRJA 3CXLA 2C0TA 2DM0A 5DF6A 2C9WA 2CI8A 4F5BA 2ETZA 3OB2B 2DLYA 4EY0A 2DLZA 3M7FA 2OQ1A 4K45A 3PQZA 1AYBA 1JYRA 1FHSA 1OPLA 1F2FA 1O4OA 2Y1NA 3MAZA 4LUEA 3N7YA 3CD3A 1O4QA 3IMJA 1O4IA 3GXXA 4TZIA 4JGHA 2AOAA 3QWYA 1A1CA 2PLDA 1YVLA 2L4KA 1O46A 4DGPA 3VRRA 2LNXA 3PSKA 1F1WA 5KAZA 4OHHA 3TL0A 1RPYA 1SHBA 4OHDA 1G83A 1HCTB 2CI9A 4NWFA 1QG1E 3CWGA 4A4CA 1KC2A 3BUMB 3QWXX 1CWDL 2HDVA 2EU0A 1MILA 4F5AA 3K2MA 1GRIA 1KA6A 2RVFA 3K2TA 1D1ZA 1RQQC 1O4HA 1PICA 1ZFPE 5HKWA 3PS5A 1O4EA 5GJIA 1A08A 4U17A 3PFVA 3VRYA 1BLJA 1O4CA 1TZEE 3VS7A 1R1PA 3PLFB 4F59A 1O4FA 2IUIA 4OHEA 2VIFA 1SPRA 2DVJA 3S9KA 2CR4A 1A1AA 1QCFA 4XZ0A 4A4BA 5GJHA 2H8HA 5I6VA 4JE4A 1BMBA 1A07A 3OP0A 2GE9A 1FBVA 3GXWA 1O43A 1BHFA 3VS5A 1X6CA 3LYVA 1OO4A 1O4AA 2EL8A 1O4KA 1I3ZA 3BUNB 1UUSA 2EO3A 2HUWA 1LUMA 1CSYA 5BO4A 3VRPA 4FBNA 2ABLA 1LUIA 3VS3A 2IZVA 4P9VA 4K11A 2H5KA 3UYOA 2DX0A 2FCIA 5AXIA 2RSYA 5CDWA 1A1BA 3PJPA 2CIAA 2LNWA 2PNBA 1LUNA 1BM2A 1D4TA 4JEGA 1AOTF 2H46E 1M61A 3S8OA 1UURA 5DC9A 3GQIB 3VS6A 2KGYA 5J3XA 2L6KA 2EO6A 2QMSA 2MK2A 3BUWB 3PSJA 2HCKA 3N8MA 3US4A 1O45A 1BKMA 1FBZA 1Y1UA 2HMHA 1JWOA 2XP1A 4E68A
chains in the Genus database with same CATH topology
1FMKA 1TCEA 3EAZA 3OVEA 5EG3B 1A81A 3VRQA 1OPKA 1FU5A 3BUXB 4X6SA 5AULA 1JU5A 1NZLA 1O4GA 4WWQA 1K9AA 1AOUF 4U1PA 1O4NA 2CS0A 1A1EA 1IJRA 1CWEA 3VS4A 2LQNA 1B47A 3VROA 4ROJA 2RORA 1SKJA 2B3OA 2IUGA 1O4BA 1D4WA 4GPLB 5DC0B 1BG1A 5HKYA 4E93A 3EACA 4K2RA 5IBMA 1A09A 1BHHA 1AYCA 2CBLA 1FYRA 1RJAA 2MQIA 3OV1A 1SHDA 3MXYA 2L3TA 2BBUA 4OHIA 3VGOA 3CBLA 4H1OA 1XA6A 2ECDA 3BKBA 3KFJA 1IS0A 4XZ1A 4OHLA 3VRZA 3ZNIA 3HIZB 4QSYA 1X0NA 2CRHA 2K7AB 1O42A 4DGXA 2DCRA 5EHRA 1FU6A 4EIHA 5IBSA 2KK6A 4NWGA 4P9ZA 2JYQA 1GHUA 1LKKA 1O44A 2MC1A 1O4RA 2LQWA 2MRKA 1BFJA 2C0OA 2RMXA 4K44A 1CSZA 1KSWA 3N84A 3NHNA 3VRNA 4M4ZA 3VS0A 1O4LA 1QADA 2FO0A 4LUDA 2AUGA 3S8NA 2Y3AB 4GWFA 2SHPA 2PNAA 1BFIA 3WA4A 3IMDA 2KNOA 4H34A 4GL9E 5EEQA 1AB2A 4L1BB 1BHHB 1O41A 3HHMB 1MW4A 3BUOB 4D8KA 2HDXA 1AYDA 3TKZA 1R1SA 1BLKA 3VS2A 5DC4A 3MXCA 1Y57A 2AOBA 1CJ1A 2EYZA 1O48A 1LCKA 1OO3A 2Y1MA 1Z3KA 1WQUA 2YU7A 1X27A 2IUHA 1H9OA 1BF5A 1HCSB 1P13A 1AD5A 2EYVA 2PTKA 1NZVA 5EELA 2C0IA 2LCTA 3IN7A 2EYYA 3T04A 5EHPA 1NRVA 3IN8A 5D0JA 5HKZA 2EKXA 4FL3A 1O4MA 1LKLA 1M27A 1SPSA 1SHAA 1O47A 2EOBA 4FL2A 1O49A 1JYQA 2K79B 2GSBA 1O4PA 1KA7A 1O4DA 1BKLA 1JYUA 1O4JA 2PLEA 2SRCA 3C7IA 3HCKA 1YVHA 2OZOA 3UF4A 3OB1B 1AYAA 2YSXA 1R1QA 3VS1A 1LUKA 1LCJA 3S8LA 2MRJA 3CXLA 2C0TA 2DM0A 5DF6A 2C9WA 2CI8A 4F5BA 2ETZA 3OB2B 2DLYA 4EY0A 2DLZA 3M7FA 2OQ1A 4K45A 3PQZA 1AYBA 1JYRA 1FHSA 1OPLA 1F2FA 1O4OA 2Y1NA 3MAZA 4LUEA 3N7YA 3CD3A 1O4QA 3IMJA 1O4IA 3GXXA 4TZIA 4JGHA 2AOAA 3QWYA 1A1CA 2PLDA 1YVLA 2L4KA 1O46A 4DGPA 3VRRA 2LNXA 3PSKA 1F1WA 5KAZA 4OHHA 3TL0A 1RPYA 1SHBA 4OHDA 1G83A 1HCTB 2CI9A 4NWFA 1QG1E 3CWGA 4A4CA 1KC2A 3BUMB 3QWXX 1CWDL 2HDVA 2EU0A 1MILA 4F5AA 3K2MA 1GRIA 1KA6A 2RVFA 1D1ZA 1RQQC 1O4HA 1PICA 1ZFPE 5HKWA 3PS5A 1O4EA 5GJIA 1A08A 4U17A 3PFVA 3VRYA 1BLJA 1O4CA 1TZEE 3VS7A 1R1PA 3PLFB 4F59A 1O4FA 2IUIA 4OHEA 2VIFA 1SPRA 2DVJA 3S9KA 2CR4A 1A1AA 1QCFA 4XZ0A 4A4BA 5GJHA 2H8HA 5I6VA 4JE4A 1BMBA 1A07A 3OP0A 2GE9A 1FBVA 3GXWA 1O43A 1BHFA 3VS5A 1X6CA 1OO4A 1O4AA 2EL8A 1O4KA 1I3ZA 3BUNB 1UUSA 2EO3A 2HUWA 1LUMA 1CSYA 5BO4A 3VRPA 4FBNA 2ABLA 1LUIA 3VS3A 2IZVA 4P9VA 4K11A 2H5KA 3UYOA 2DX0A 2FCIA 5AXIA 2RSYA 5CDWA 1A1BA 3PJPA 2CIAA 2LNWA 2PNBA 1LUNA 1BM2A 1D4TA 4JEGA 1AOTF 2H46E 1M61A 3S8OA 1UURA 5DC9A 3GQIB 3VS6A 5J3XA 2L6KA 2EO6A 2QMSA 2MK2A 3BUWB 3PSJA 2HCKA 3N8MA 3US4A 1O45A 1BKMA 1FBZA 1Y1UA 2HMHA 1JWOA 2XP1A 4E68A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FMK A;  1TCE A;  3EAZ A;  3OVE A;  5EG3 B;  1A81 A;  3VRQ A;  1OPK A;  1FU5 A;  3BUX B;  4X6S A;  5AUL A;  1JU5 A;  1NZL A;  1O4G A;  4WWQ A;  1K9A A;  1AOU F;  4U1P A;  1O4N A;  2CS0 A;  1A1E A;  1IJR A;  1CWE A;  3VS4 A;  2LQN A;  1B47 A;  3VRO A;  4ROJ A;  2ROR A;  1SKJ A;  2B3O A;  2IUG A;  1O4B A;  1D4W A;  4GPL B;  5DC0 B;  1BG1 A;  5HKY A;  4E93 A;  3EAC A;  4K2R A;  5IBM A;  1A09 A;  1BHH A;  1AYC A;  2CBL A;  1FYR A;  1RJA A;  2MQI A;  3OV1 A;  1SHD A;  3MXY A;  2L3T A;  2BBU A;  4OHI A;  3VGO A;  3CBL A;  4H1O A;  1XA6 A;  2ECD A;  3BKB A;  3KFJ A;  1IS0 A;  4XZ1 A;  4OHL A;  3VRZ A;  3ZNI A;  3HIZ B;  4QSY A;  1X0N A;  2CRH A;  2K7A B;  1O42 A;  4DGX A;  2DCR A;  5EHR A;  1FU6 A;  4EIH A;  5IBS A;  2KK6 A;  4NWG A;  4P9Z A;  2JYQ A;  1GHU A;  1LKK A;  1O44 A;  2MC1 A;  1O4R A;  2LQW A;  2MRK A;  1BFJ A;  2C0O A;  2RMX A;  4K44 A;  1CSZ A;  1KSW A;  3N84 A;  3NHN A;  3VRN A;  4M4Z A;  3VS0 A;  1O4L A;  1QAD A;  2FO0 A;  4LUD A;  2AUG A;  3S8N A;  2Y3A B;  4GWF A;  2SHP A;  2PNA A;  1BFI A;  3WA4 A;  3IMD A;  2KNO A;  4H34 A;  4GL9 E;  5EEQ A;  1AB2 A;  4L1B B;  1BHH B;  1O41 A;  3HHM B;  1MW4 A;  3BUO B;  4D8K A;  2HDX A;  1AYD A;  3TKZ A;  1R1S A;  1BLK A;  3VS2 A;  5DC4 A;  3MXC A;  1Y57 A;  2AOB A;  1CJ1 A;  2EYZ A;  1O48 A;  1LCK A;  1OO3 A;  2Y1M A;  1Z3K A;  1WQU A;  2YU7 A;  1X27 A;  2IUH A;  1H9O A;  1BF5 A;  1HCS B;  1P13 A;  1AD5 A;  2EYV A;  2PTK A;  1NZV A;  5EEL A;  2C0I A;  2LCT A;  3IN7 A;  2EYY A;  3T04 A;  5EHP A;  1NRV A;  3IN8 A;  5D0J A;  5HKZ A;  2EKX A;  4FL3 A;  1O4M A;  1LKL A;  1M27 A;  1SPS A;  1SHA A;  1O47 A;  2EOB A;  4FL2 A;  1O49 A;  1JYQ A;  2K79 B;  2GSB A;  1O4P A;  1KA7 A;  1O4D A;  1BKL A;  1JYU A;  1O4J A;  2PLE A;  2SRC A;  3C7I A;  3HCK A;  1YVH A;  2OZO A;  3UF4 A;  3OB1 B;  1AYA A;  2YSX A;  1R1Q A;  3VS1 A;  1LUK A;  1LCJ A;  3S8L A;  2MRJ A;  3CXL A;  2C0T A;  2DM0 A;  5DF6 A;  2C9W A;  2CI8 A;  4F5B A;  2ETZ A;  3OB2 B;  2DLY A;  4EY0 A;  2DLZ A;  3M7F A;  2OQ1 A;  4K45 A;  3PQZ A;  1AYB A;  1JYR A;  1FHS A;  1OPL A;  1F2F A;  1O4O A;  2Y1N A;  3MAZ A;  4LUE A;  3N7Y A;  3CD3 A;  1O4Q A;  3IMJ A;  1O4I A;  3GXX A;  4TZI A;  4JGH A;  2AOA A;  3QWY A;  1A1C A;  2PLD A;  1YVL A;  2L4K A;  1O46 A;  4DGP A;  3VRR A;  2LNX A;  3PSK A;  1F1W A;  5KAZ A;  4OHH A;  3TL0 A;  1RPY A;  1SHB A;  4OHD A;  1G83 A;  1HCT B;  2CI9 A;  4NWF A;  1QG1 E;  3CWG A;  4A4C A;  1KC2 A;  3BUM B;  3QWX X;  1CWD L;  2HDV A;  2EU0 A;  1MIL A;  4F5A A;  3K2M A;  1GRI A;  1KA6 A;  2RVF A;  1D1Z A;  1RQQ C;  1O4H A;  1PIC A;  1ZFP E;  5HKW A;  3PS5 A;  1O4E A;  5GJI A;  1A08 A;  4U17 A;  3PFV A;  3VRY A;  1BLJ A;  1O4C A;  1TZE E;  3VS7 A;  1R1P A;  3PLF B;  4F59 A;  1O4F A;  2IUI A;  4OHE A;  2VIF A;  1SPR A;  2DVJ A;  3S9K A;  2CR4 A;  1A1A A;  1QCF A;  4XZ0 A;  4A4B A;  5GJH A;  2H8H A;  5I6V A;  4JE4 A;  1BMB A;  1A07 A;  3OP0 A;  2GE9 A;  1FBV A;  3GXW A;  1O43 A;  1BHF A;  3VS5 A;  1X6C A;  1OO4 A;  1O4A A;  2EL8 A;  1O4K A;  1I3Z A;  3BUN B;  1UUS A;  2EO3 A;  2HUW A;  1LUM A;  1CSY A;  5BO4 A;  3VRP A;  4FBN A;  2ABL A;  1LUI A;  3VS3 A;  2IZV A;  4P9V A;  4K11 A;  2H5K A;  3UYO A;  2DX0 A;  2FCI A;  5AXI A;  2RSY A;  5CDW A;  1A1B A;  3PJP A;  2CIA A;  2LNW A;  2PNB A;  1LUN A;  1BM2 A;  1D4T A;  4JEG A;  1AOT F;  2H46 E;  1M61 A;  3S8O A;  1UUR A;  5DC9 A;  3GQI B;  3VS6 A;  5J3X A;  2L6K A;  2EO6 A;  2QMS A;  2MK2 A;  3BUW B;  3PSJ A;  2HCK A;  3N8M A;  3US4 A;  1O45 A;  1BKM A;  1FBZ A;  1Y1U A;  2HMH A;  1JWO A;  2XP1 A;  4E68 A; 
#chains in the Genus database with same CATH topology
 1FMK A;  1TCE A;  3EAZ A;  3OVE A;  5EG3 B;  1A81 A;  3VRQ A;  1OPK A;  1FU5 A;  3BUX B;  4X6S A;  5AUL A;  1JU5 A;  1NZL A;  1O4G A;  4WWQ A;  1K9A A;  1AOU F;  4U1P A;  1O4N A;  2CS0 A;  1A1E A;  1IJR A;  1CWE A;  3VS4 A;  2LQN A;  1B47 A;  3VRO A;  4ROJ A;  2ROR A;  1SKJ A;  2B3O A;  2IUG A;  1O4B A;  1D4W A;  4GPL B;  5DC0 B;  1BG1 A;  5HKY A;  4E93 A;  3EAC A;  4K2R A;  5IBM A;  1A09 A;  1BHH A;  1AYC A;  2CBL A;  1FYR A;  1RJA A;  2MQI A;  3OV1 A;  1SHD A;  3MXY A;  2L3T A;  2BBU A;  4OHI A;  3VGO A;  3CBL A;  4H1O A;  1XA6 A;  2ECD A;  3BKB A;  3KFJ A;  1IS0 A;  4XZ1 A;  4OHL A;  3VRZ A;  3ZNI A;  3HIZ B;  4QSY A;  1X0N A;  2CRH A;  2K7A B;  1O42 A;  4DGX A;  2DCR A;  5EHR A;  1FU6 A;  4EIH A;  5IBS A;  2KK6 A;  4NWG A;  4P9Z A;  2JYQ A;  1GHU A;  1LKK A;  1O44 A;  2MC1 A;  1O4R A;  2LQW A;  2MRK A;  1BFJ A;  2C0O A;  2RMX A;  4K44 A;  1CSZ A;  1KSW A;  3N84 A;  3NHN A;  3VRN A;  4M4Z A;  3VS0 A;  1O4L A;  1QAD A;  2FO0 A;  4LUD A;  2AUG A;  3S8N A;  2Y3A B;  4GWF A;  2SHP A;  2PNA A;  1BFI A;  3WA4 A;  3IMD A;  2KNO A;  4H34 A;  4GL9 E;  5EEQ A;  1AB2 A;  4L1B B;  1BHH B;  1O41 A;  3HHM B;  1MW4 A;  3BUO B;  4D8K A;  2HDX A;  1AYD A;  3TKZ A;  1R1S A;  1BLK A;  3VS2 A;  5DC4 A;  3MXC A;  1Y57 A;  2AOB A;  1CJ1 A;  2EYZ A;  1O48 A;  1LCK A;  1OO3 A;  2Y1M A;  1Z3K A;  1WQU A;  2YU7 A;  2LRA A;  1X27 A;  2IUH A;  1H9O A;  1BF5 A;  1HCS B;  1P13 A;  1AD5 A;  2EYV A;  2PTK A;  1NZV A;  5EEL A;  2C0I A;  2LCT A;  3IN7 A;  2EYY A;  3T04 A;  5EHP A;  1NRV A;  3IN8 A;  5D0J A;  5HKZ A;  2EKX A;  4FL3 A;  1O4M A;  1LKL A;  1M27 A;  1SPS A;  1SHA A;  1O47 A;  2EOB A;  4FL2 A;  1O49 A;  1JYQ A;  2K79 B;  2GSB A;  1O4P A;  1KA7 A;  1O4D A;  1BKL A;  1JYU A;  1O4J A;  2PLE A;  2SRC A;  3C7I A;  3HCK A;  1YVH A;  2OZO A;  3UF4 A;  3OB1 B;  1AYA A;  2YSX A;  1R1Q A;  3VS1 A;  1LUK A;  1LCJ A;  3S8L A;  2MRJ A;  3CXL A;  2C0T A;  2DM0 A;  5DF6 A;  2C9W A;  2CI8 A;  4F5B A;  2ETZ A;  3OB2 B;  2DLY A;  4EY0 A;  2DLZ A;  3M7F A;  2OQ1 A;  4K45 A;  3PQZ A;  1AYB A;  1JYR A;  1FHS A;  1OPL A;  1F2F A;  1O4O A;  2Y1N A;  3MAZ A;  4LUE A;  3N7Y A;  3CD3 A;  1O4Q A;  3IMJ A;  1O4I A;  3GXX A;  4TZI A;  4JGH A;  2AOA A;  3QWY A;  1A1C A;  2PLD A;  1YVL A;  2L4K A;  1O46 A;  4DGP A;  3VRR A;  2LNX A;  3PSK A;  1F1W A;  5KAZ A;  4OHH A;  3TL0 A;  1RPY A;  1SHB A;  4OHD A;  1G83 A;  1HCT B;  2CI9 A;  4NWF A;  1QG1 E;  3CWG A;  4A4C A;  1KC2 A;  3BUM B;  3QWX X;  1CWD L;  2HDV A;  2EU0 A;  1MIL A;  4F5A A;  3K2M A;  1GRI A;  1KA6 A;  2RVF A;  3K2T A;  1D1Z A;  1RQQ C;  1O4H A;  1PIC A;  1ZFP E;  5HKW A;  3PS5 A;  1O4E A;  5GJI A;  1A08 A;  4U17 A;  3PFV A;  3VRY A;  1BLJ A;  1O4C A;  1TZE E;  3VS7 A;  1R1P A;  3PLF B;  4F59 A;  1O4F A;  2IUI A;  4OHE A;  2VIF A;  1SPR A;  2DVJ A;  3S9K A;  2CR4 A;  1A1A A;  1QCF A;  4XZ0 A;  4A4B A;  5GJH A;  2H8H A;  5I6V A;  4JE4 A;  1BMB A;  1A07 A;  3OP0 A;  2GE9 A;  1FBV A;  3GXW A;  1O43 A;  1BHF A;  3VS5 A;  1X6C A;  3LYV A;  1OO4 A;  1O4A A;  2EL8 A;  1O4K A;  1I3Z A;  3BUN B;  1UUS A;  2EO3 A;  2HUW A;  1LUM A;  1CSY A;  5BO4 A;  3VRP A;  4FBN A;  2ABL A;  1LUI A;  3VS3 A;  2IZV A;  4P9V A;  4K11 A;  2H5K A;  3UYO A;  2DX0 A;  2FCI A;  5AXI A;  2RSY A;  5CDW A;  1A1B A;  3PJP A;  2CIA A;  2LNW A;  2PNB A;  1LUN A;  1BM2 A;  1D4T A;  4JEG A;  1AOT F;  2H46 E;  1M61 A;  3S8O A;  1UUR A;  5DC9 A;  3GQI B;  3VS6 A;  2KGY A;  5J3X A;  2L6K A;  2EO6 A;  2QMS A;  2MK2 A;  3BUW B;  3PSJ A;  2HCK A;  3N8M A;  3US4 A;  1O45 A;  1BKM A;  1FBZ A;  1Y1U A;  2HMH A;  1JWO A;  2XP1 A;  4E68 A; 
#chains in the Genus database with same CATH homology
 1FMK A;  1TCE A;  3EAZ A;  3OVE A;  5EG3 B;  1A81 A;  3VRQ A;  1OPK A;  1FU5 A;  3BUX B;  4X6S A;  5AUL A;  1JU5 A;  1NZL A;  1O4G A;  4WWQ A;  1K9A A;  1AOU F;  4U1P A;  1O4N A;  2CS0 A;  1A1E A;  1IJR A;  1CWE A;  3VS4 A;  2LQN A;  1B47 A;  3VRO A;  4ROJ A;  2ROR A;  1SKJ A;  2B3O A;  2IUG A;  1O4B A;  1D4W A;  4GPL B;  5DC0 B;  1BG1 A;  5HKY A;  4E93 A;  3EAC A;  4K2R A;  5IBM A;  1A09 A;  1BHH A;  1AYC A;  2CBL A;  1FYR A;  1RJA A;  2MQI A;  3OV1 A;  1SHD A;  3MXY A;  2L3T A;  2BBU A;  4OHI A;  3VGO A;  3CBL A;  4H1O A;  1XA6 A;  2ECD A;  3BKB A;  3KFJ A;  1IS0 A;  4XZ1 A;  4OHL A;  3VRZ A;  3ZNI A;  3HIZ B;  4QSY A;  1X0N A;  2CRH A;  2K7A B;  1O42 A;  4DGX A;  2DCR A;  5EHR A;  1FU6 A;  4EIH A;  5IBS A;  2KK6 A;  4NWG A;  4P9Z A;  2JYQ A;  1GHU A;  1LKK A;  1O44 A;  2MC1 A;  1O4R A;  2LQW A;  2MRK A;  1BFJ A;  2C0O A;  2RMX A;  4K44 A;  1CSZ A;  1KSW A;  3N84 A;  3NHN A;  3VRN A;  4M4Z A;  3VS0 A;  1O4L A;  1QAD A;  2FO0 A;  4LUD A;  2AUG A;  3S8N A;  2Y3A B;  4GWF A;  2SHP A;  2PNA A;  1BFI A;  3WA4 A;  3IMD A;  2KNO A;  4H34 A;  4GL9 E;  5EEQ A;  1AB2 A;  4L1B B;  1BHH B;  1O41 A;  3HHM B;  1MW4 A;  3BUO B;  4D8K A;  2HDX A;  1AYD A;  3TKZ A;  1R1S A;  1BLK A;  3VS2 A;  5DC4 A;  3MXC A;  1Y57 A;  2AOB A;  1CJ1 A;  2EYZ A;  1O48 A;  1LCK A;  1OO3 A;  2Y1M A;  1Z3K A;  1WQU A;  2YU7 A;  1X27 A;  2IUH A;  1H9O A;  1BF5 A;  1HCS B;  1P13 A;  1AD5 A;  2EYV A;  2PTK A;  1NZV A;  5EEL A;  2C0I A;  2LCT A;  3IN7 A;  2EYY A;  3T04 A;  5EHP A;  1NRV A;  3IN8 A;  5D0J A;  5HKZ A;  2EKX A;  4FL3 A;  1O4M A;  1LKL A;  1M27 A;  1SPS A;  1SHA A;  1O47 A;  2EOB A;  4FL2 A;  1O49 A;  1JYQ A;  2K79 B;  2GSB A;  1O4P A;  1KA7 A;  1O4D A;  1BKL A;  1JYU A;  1O4J A;  2PLE A;  2SRC A;  3C7I A;  3HCK A;  1YVH A;  2OZO A;  3UF4 A;  3OB1 B;  1AYA A;  2YSX A;  1R1Q A;  3VS1 A;  1LUK A;  1LCJ A;  3S8L A;  2MRJ A;  3CXL A;  2C0T A;  2DM0 A;  5DF6 A;  2C9W A;  2CI8 A;  4F5B A;  2ETZ A;  3OB2 B;  2DLY A;  4EY0 A;  2DLZ A;  3M7F A;  2OQ1 A;  4K45 A;  3PQZ A;  1AYB A;  1JYR A;  1FHS A;  1OPL A;  1F2F A;  1O4O A;  2Y1N A;  3MAZ A;  4LUE A;  3N7Y A;  3CD3 A;  1O4Q A;  3IMJ A;  1O4I A;  3GXX A;  4TZI A;  4JGH A;  2AOA A;  3QWY A;  1A1C A;  2PLD A;  1YVL A;  2L4K A;  1O46 A;  4DGP A;  3VRR A;  2LNX A;  3PSK A;  1F1W A;  5KAZ A;  4OHH A;  3TL0 A;  1RPY A;  1SHB A;  4OHD A;  1G83 A;  1HCT B;  2CI9 A;  4NWF A;  1QG1 E;  3CWG A;  4A4C A;  1KC2 A;  3BUM B;  3QWX X;  1CWD L;  2HDV A;  2EU0 A;  1MIL A;  4F5A A;  3K2M A;  1GRI A;  1KA6 A;  2RVF A;  1D1Z A;  1RQQ C;  1O4H A;  1PIC A;  1ZFP E;  5HKW A;  3PS5 A;  1O4E A;  5GJI A;  1A08 A;  4U17 A;  3PFV A;  3VRY A;  1BLJ A;  1O4C A;  1TZE E;  3VS7 A;  1R1P A;  3PLF B;  4F59 A;  1O4F A;  2IUI A;  4OHE A;  2VIF A;  1SPR A;  2DVJ A;  3S9K A;  2CR4 A;  1A1A A;  1QCF A;  4XZ0 A;  4A4B A;  5GJH A;  2H8H A;  5I6V A;  4JE4 A;  1BMB A;  1A07 A;  3OP0 A;  2GE9 A;  1FBV A;  3GXW A;  1O43 A;  1BHF A;  3VS5 A;  1X6C A;  1OO4 A;  1O4A A;  2EL8 A;  1O4K A;  1I3Z A;  3BUN B;  1UUS A;  2EO3 A;  2HUW A;  1LUM A;  1CSY A;  5BO4 A;  3VRP A;  4FBN A;  2ABL A;  1LUI A;  3VS3 A;  2IZV A;  4P9V A;  4K11 A;  2H5K A;  3UYO A;  2DX0 A;  2FCI A;  5AXI A;  2RSY A;  5CDW A;  1A1B A;  3PJP A;  2CIA A;  2LNW A;  2PNB A;  1LUN A;  1BM2 A;  1D4T A;  4JEG A;  1AOT F;  2H46 E;  1M61 A;  3S8O A;  1UUR A;  5DC9 A;  3GQI B;  3VS6 A;  5J3X A;  2L6K A;  2EO6 A;  2QMS A;  2MK2 A;  3BUW B;  3PSJ A;  2HCK A;  3N8M A;  3US4 A;  1O45 A;  1BKM A;  1FBZ A;  1Y1U A;  2HMH A;  1JWO A;  2XP1 A;  4E68 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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