2Y3AB

Crystal structure of p110beta in complex with icsh2 of p85beta and the drug gdc-0941
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
274
structure length
236
Chain Sequence
KVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Lipid Kinase P110Beta-P85Beta Elucidates an Unusual Sh2-Domain-Mediated Inhibitory Mechanism.
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUB
total genus 61
structure length 236
sequence length 274
ec nomenclature
pdb deposition date 2010-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2y3aB02
4K11A 2YSXA 1X6CA 1CWDL 1AYBA 1X0NA 2IUGA 1JYRA 2EO3A 3CWGA 4WWQA 1A81A 3PSJA 1CWEA 2YU7A 3UF4A 1MW4A 1LCJA 2LNXA 2DVJA 2IUIA 2L4KA 2HMHA 2EKXA 1HCSB 2LQWA 5CDWA 4OHLA 3PS5A 2CR4A 3BUMB 3TKZA 1O48A 5BO4A 2MRKA 1QADA 2CIAA 2MRJA 4F5BA 1BMBA 2ETZA 1AOUF 3BUNB 1O42A 1R1QA 2IUHA 1SPSA 1KA7A 1BFIA 1NZLA 3CXLA 4F5AA 2OZOA 4H34A 3VS4A 1MILA 2C9WA 4A4BA 3HIZB 1QCFA 1Y57A 3BUXB 1O4PA 2VIFA 1AOTF 3K2MA 2HDVA 3M7FA 4P9ZA 2PNBA 1OPKA 2BBUA 5HKWA 5AXIA 1A1AA 3VS5A 1GHUA 1KSWA 4U17A 3GXWA 1D1ZA 4DGPA 4E68A 2K7AB 4X6SA 2SHPA 3NHNA 3BUOB 2PLDA 3HCKA 3MXYA 1ZFPE 1K9AA 1TCEA 1F1WA 1O41A 4EIHA 5KAZA 5GJHA 2PNAA 3TL0A 2H46E 3N8MA 1O47A 1BLJA 3OB1B 1R1PA 3VGOA 4U1PA 2EU0A 1BKMA 2HUWA 1FBVA 1JYUA 1R1SA 1AB2A 2IZVA 1AYDA 1O4IA 2EL8A 3PFVA 4OHIA 4LUEA 1Z3KA 1M27A 1Y1UA 1BM2A 1O49A 1M61A 1AD5A 2FO0A 1O4HA 2LCTA 1O4DA 3VS1A 1KC2A 1HCTB 3VRZA 1NZVA 2Y1NA 2OQ1A 2GSBA 5DC9A 1G83A 4L1BB 2C0IA 1X27A 5AULA 1OO4A 1BHHB 1NRVA 2XP1A 2DM0A 2DX0A 2QMSA 2MQIA 3MAZA 3VS2A 5DC4A 1H9OA 1AYCA 4NWFA 3VRPA 1YVLA 4M4ZA 4K45A 1GRIA 5EG3B 1O4LA 3T04A 1RJAA 1D4TA 3QWYA 1FBZA 1BFJA 2EYVA 2LNWA 4GWFA 1A1BA 4QSYA 4NWGA 1O4FA 4TZIA 3VS6A 4JEGA 5DF6A 2CI9A 1WQUA 4DGXA 1OO3A 3VS7A 4ROJA 2FCIA 4XZ1A 3WA4A 2CBLA 1FYRA 1O4KA 1BKLA 1O43A 1LKLA 1O4BA 1CSYA 1KA6A 2AOAA 2DCRA 2DLZA 1O4JA 2RORA 1JWOA 1O4QA 2MK2A 3UYOA 1SHDA 4GL9E 2CI8A 1A09A 2KNOA 3BKBA 3VRQA 1FHSA 1UURA 3OB2B 4F59A 3N84A 1O4GA 3BUWB 3S8LA 5DC0B 3ZNIA 3S8NA 2RMXA 3S9KA 2CRHA 2EYZA 2MC1A 1BHHA 2L6KA 1O4OA 5GJIA 3IN8A 3PJPA 4XZ0A 2RVFA 4EY0A 1JYQA 2EYYA 1YVHA 2CS0A 2H5KA 3CBLA 4K2RA 1A1EA 1TZEE 1B47A 1UUSA 3VROA 1RPYA 2RSYA 2C0OA 1IS0A 1SHAA 1F2FA 2GE9A 2H8HA 3HHMB 1RQQC 2PTKA 5EHPA 5D0JA 1CSZA 3VRRA 4FL3A 5EEQA 3GXXA 3C7IA 2Y3AB 1LUMA 4OHHA 3IMDA 3PQZA 1O45A 1O46A 2KK6A 4E93A 1AYAA 3IN7A 3CD3A 1XA6A 2JYQA 1IJRA 1QG1E 4GPLB 1P13A 2SRCA 2L3TA 1SPRA 1LUIA 1O4MA 1PICA 1FU5A 1OPLA 2DLYA 2HDXA 3PLFB 1BHFA 1LUNA 5I6VA 4D8KA 1O4CA 3OVEA 1D4WA 3VS0A 1A1CA 2LQNA 1A07A 3MXCA 3GQIB 4A4CA 3OV1A 2B3OA 1SHBA 2ECDA 3VS3A 3QWXX 1FU6A 4FL2A 4FBNA 4OHEA 5EELA 2AOBA 4K44A 4P9VA 3OP0A 2K79B 4OHDA 3S8OA 2ABLA 2EO6A 2Y1MA 1FMKA 4LUDA 3EAZA 1BF5A 3IMJA 3VRYA 3PSKA 5HKYA 1BG1A 2C0TA 1A08A 1JU5A 2PLEA 1O4NA 5J3XA 4H1OA 1LCKA 1O4AA 2AUGA 5IBSA 3N7YA 1LKKA 4JE4A 1O44A 3VRNA 1O4EA 4JGHA 3EACA 2HCKA 3KFJA 1BLKA 1SKJA 1I3ZA 1CJ1A 1LUKA 1O4RA 5IBMA 5HKZA 3US4A 5EHRA 2EOBA
chains in the Genus database with same CATH superfamily
4K11A 2YSXA 1X6CA 1CWDL 1AYBA 1X0NA 2IUGA 1JYRA 2EO3A 3CWGA 4WWQA 1A81A 3PSJA 1CWEA 2YU7A 3UF4A 1MW4A 1LCJA 2LNXA 2DVJA 2IUIA 2L4KA 2HMHA 2EKXA 1HCSB 2LQWA 5CDWA 4OHLA 3PS5A 2CR4A 3BUMB 3TKZA 1O48A 5BO4A 2MRKA 1QADA 2CIAA 2MRJA 4F5BA 1BMBA 2ETZA 1AOUF 3BUNB 1O42A 1R1QA 2IUHA 1SPSA 1KA7A 1BFIA 1NZLA 3CXLA 4F5AA 2OZOA 4H34A 3VS4A 1MILA 2C9WA 4A4BA 3HIZB 1QCFA 1Y57A 3BUXB 1O4PA 2VIFA 1AOTF 3K2MA 2HDVA 3M7FA 4P9ZA 2PNBA 1OPKA 2BBUA 5HKWA 5AXIA 1A1AA 3VS5A 1GHUA 1KSWA 4U17A 3GXWA 1D1ZA 4DGPA 4E68A 2K7AB 2KGYA 4X6SA 2SHPA 3NHNA 3BUOB 2PLDA 3HCKA 3MXYA 1ZFPE 1K9AA 1TCEA 1F1WA 1O41A 4EIHA 5KAZA 5GJHA 2PNAA 3TL0A 2H46E 3N8MA 1O47A 1BLJA 3OB1B 1R1PA 3VGOA 4U1PA 2EU0A 1BKMA 2HUWA 1FBVA 1JYUA 1R1SA 1AB2A 2IZVA 1AYDA 1O4IA 2EL8A 3PFVA 4OHIA 4LUEA 1Z3KA 1M27A 1Y1UA 1BM2A 1O49A 1M61A 1AD5A 2FO0A 1O4HA 2LCTA 1O4DA 3VS1A 1KC2A 1HCTB 3VRZA 1NZVA 2Y1NA 2OQ1A 2GSBA 5DC9A 1G83A 4L1BB 2C0IA 1X27A 5AULA 1OO4A 1BHHB 1NRVA 2XP1A 2DM0A 2DX0A 2QMSA 2MQIA 3MAZA 3VS2A 5DC4A 1H9OA 1AYCA 4NWFA 3VRPA 1YVLA 4M4ZA 4K45A 1GRIA 5EG3B 1O4LA 3T04A 1RJAA 1D4TA 3QWYA 1FBZA 3K2TA 1BFJA 2EYVA 2LNWA 4GWFA 1A1BA 4QSYA 4NWGA 1O4FA 4TZIA 3VS6A 4JEGA 5DF6A 2CI9A 1WQUA 4DGXA 1OO3A 3VS7A 4ROJA 2FCIA 4XZ1A 3WA4A 2CBLA 1FYRA 1O4KA 1BKLA 1O43A 1LKLA 1O4BA 1CSYA 1KA6A 2AOAA 2DCRA 2DLZA 1O4JA 2RORA 1JWOA 1O4QA 2MK2A 3UYOA 1SHDA 4GL9E 2CI8A 1A09A 2KNOA 3BKBA 3VRQA 1FHSA 1UURA 3OB2B 4F59A 3N84A 1O4GA 3BUWB 3S8LA 5DC0B 3ZNIA 3S8NA 2RMXA 3S9KA 2CRHA 2EYZA 2MC1A 1BHHA 2L6KA 1O4OA 5GJIA 3IN8A 3PJPA 4XZ0A 2RVFA 4EY0A 1JYQA 2EYYA 1YVHA 2CS0A 2H5KA 3CBLA 4K2RA 1A1EA 1TZEE 1B47A 1UUSA 3VROA 1RPYA 2RSYA 2C0OA 1IS0A 1SHAA 1F2FA 2GE9A 2H8HA 3HHMB 1RQQC 2PTKA 5EHPA 5D0JA 1CSZA 3VRRA 4FL3A 5EEQA 3GXXA 3C7IA 2Y3AB 1LUMA 4OHHA 3IMDA 3PQZA 1O45A 1O46A 2KK6A 4E93A 1AYAA 3IN7A 3CD3A 1XA6A 2JYQA 1IJRA 1QG1E 4GPLB 1P13A 2SRCA 2L3TA 1SPRA 1LUIA 1O4MA 1PICA 1FU5A 1OPLA 2DLYA 2HDXA 3PLFB 1BHFA 1LUNA 5I6VA 4D8KA 1O4CA 3OVEA 1D4WA 3VS0A 1A1CA 2LQNA 1A07A 3MXCA 3GQIB 4A4CA 3OV1A 2B3OA 1SHBA 2ECDA 3VS3A 3QWXX 1FU6A 4FL2A 4FBNA 4OHEA 5EELA 2AOBA 4K44A 4P9VA 3OP0A 2K79B 4OHDA 3S8OA 2ABLA 2EO6A 2Y1MA 1FMKA 4LUDA 3EAZA 1BF5A 3IMJA 3VRYA 3PSKA 5HKYA 1BG1A 2C0TA 1A08A 3LYVA 1JU5A 2PLEA 1O4NA 5J3XA 4H1OA 1LCKA 1O4AA 2AUGA 5IBSA 3N7YA 1LKKA 4JE4A 1O44A 3VRNA 1O4EA 2LRAA 4JGHA 3EACA 2HCKA 3KFJA 1BLKA 1SKJA 1I3ZA 1CJ1A 1LUKA 1O4RA 5IBMA 5HKZA 3US4A 5EHRA 2EOBA
chains in the Genus database with same CATH topology
4K11A 2YSXA 1X6CA 1CWDL 1AYBA 1X0NA 2IUGA 1JYRA 2EO3A 3CWGA 4WWQA 1A81A 3PSJA 1CWEA 2YU7A 3UF4A 1MW4A 1LCJA 2LNXA 2DVJA 2IUIA 2L4KA 2HMHA 2EKXA 1HCSB 2LQWA 5CDWA 4OHLA 3PS5A 2CR4A 3BUMB 3TKZA 1O48A 5BO4A 2MRKA 1QADA 2CIAA 2MRJA 4F5BA 1BMBA 2ETZA 1AOUF 3BUNB 1O42A 1R1QA 2IUHA 1SPSA 1KA7A 1BFIA 1NZLA 3CXLA 4F5AA 2OZOA 4H34A 3VS4A 1MILA 2C9WA 4A4BA 3HIZB 1QCFA 1Y57A 3BUXB 1O4PA 2VIFA 1AOTF 3K2MA 2HDVA 3M7FA 4P9ZA 2PNBA 1OPKA 2BBUA 5HKWA 5AXIA 1A1AA 3VS5A 1GHUA 1KSWA 4U17A 3GXWA 1D1ZA 4DGPA 4E68A 2K7AB 4X6SA 2SHPA 3NHNA 3BUOB 2PLDA 3HCKA 3MXYA 1ZFPE 1K9AA 1TCEA 1F1WA 1O41A 4EIHA 5KAZA 5GJHA 2PNAA 3TL0A 2H46E 3N8MA 1O47A 1BLJA 3OB1B 1R1PA 3VGOA 4U1PA 2EU0A 1BKMA 2HUWA 1FBVA 1JYUA 1R1SA 1AB2A 2IZVA 1AYDA 1O4IA 2EL8A 3PFVA 4OHIA 4LUEA 1Z3KA 1M27A 1Y1UA 1BM2A 1O49A 1M61A 1AD5A 2FO0A 1O4HA 2LCTA 1O4DA 3VS1A 1KC2A 1HCTB 3VRZA 1NZVA 2Y1NA 2OQ1A 2GSBA 5DC9A 1G83A 4L1BB 2C0IA 1X27A 5AULA 1OO4A 1BHHB 1NRVA 2XP1A 2DM0A 2DX0A 2QMSA 2MQIA 3MAZA 3VS2A 5DC4A 1H9OA 1AYCA 4NWFA 3VRPA 1YVLA 4M4ZA 4K45A 1GRIA 5EG3B 1O4LA 3T04A 1RJAA 1D4TA 3QWYA 1FBZA 1BFJA 2EYVA 2LNWA 4GWFA 1A1BA 4QSYA 4NWGA 1O4FA 4TZIA 3VS6A 4JEGA 5DF6A 2CI9A 1WQUA 4DGXA 1OO3A 3VS7A 4ROJA 2FCIA 4XZ1A 3WA4A 2CBLA 1FYRA 1O4KA 1BKLA 1O43A 1LKLA 1O4BA 1CSYA 1KA6A 2AOAA 2DCRA 2DLZA 1O4JA 2RORA 1JWOA 1O4QA 2MK2A 3UYOA 1SHDA 4GL9E 2CI8A 1A09A 2KNOA 3BKBA 3VRQA 1FHSA 1UURA 3OB2B 4F59A 3N84A 1O4GA 3BUWB 3S8LA 5DC0B 3ZNIA 3S8NA 2RMXA 3S9KA 2CRHA 2EYZA 2MC1A 1BHHA 2L6KA 1O4OA 5GJIA 3IN8A 3PJPA 4XZ0A 2RVFA 4EY0A 1JYQA 2EYYA 1YVHA 2CS0A 2H5KA 3CBLA 4K2RA 1A1EA 1TZEE 1B47A 1UUSA 3VROA 1RPYA 2RSYA 2C0OA 1IS0A 1SHAA 1F2FA 2GE9A 2H8HA 3HHMB 1RQQC 2PTKA 5EHPA 5D0JA 1CSZA 3VRRA 4FL3A 5EEQA 3GXXA 3C7IA 2Y3AB 1LUMA 4OHHA 3IMDA 3PQZA 1O45A 1O46A 2KK6A 4E93A 1AYAA 3IN7A 3CD3A 1XA6A 2JYQA 1IJRA 1QG1E 4GPLB 1P13A 2SRCA 2L3TA 1SPRA 1LUIA 1O4MA 1PICA 1FU5A 1OPLA 2DLYA 2HDXA 3PLFB 1BHFA 1LUNA 5I6VA 4D8KA 1O4CA 3OVEA 1D4WA 3VS0A 1A1CA 2LQNA 1A07A 3MXCA 3GQIB 4A4CA 3OV1A 2B3OA 1SHBA 2ECDA 3VS3A 3QWXX 1FU6A 4FL2A 4FBNA 4OHEA 5EELA 2AOBA 4K44A 4P9VA 3OP0A 2K79B 4OHDA 3S8OA 2ABLA 2EO6A 2Y1MA 1FMKA 4LUDA 3EAZA 1BF5A 3IMJA 3VRYA 3PSKA 5HKYA 1BG1A 2C0TA 1A08A 1JU5A 2PLEA 1O4NA 5J3XA 4H1OA 1LCKA 1O4AA 2AUGA 5IBSA 3N7YA 1LKKA 4JE4A 1O44A 3VRNA 1O4EA 4JGHA 3EACA 2HCKA 3KFJA 1BLKA 1SKJA 1I3ZA 1CJ1A 1LUKA 1O4RA 5IBMA 5HKZA 3US4A 5EHRA 2EOBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K11 A;  2YSX A;  1X6C A;  1CWD L;  1AYB A;  1X0N A;  2IUG A;  1JYR A;  2EO3 A;  3CWG A;  4WWQ A;  1A81 A;  3PSJ A;  1CWE A;  2YU7 A;  3UF4 A;  1MW4 A;  1LCJ A;  2LNX A;  2DVJ A;  2IUI A;  2L4K A;  2HMH A;  2EKX A;  1HCS B;  2LQW A;  5CDW A;  4OHL A;  3PS5 A;  2CR4 A;  3BUM B;  3TKZ A;  1O48 A;  5BO4 A;  2MRK A;  1QAD A;  2CIA A;  2MRJ A;  4F5B A;  1BMB A;  2ETZ A;  1AOU F;  3BUN B;  1O42 A;  1R1Q A;  2IUH A;  1SPS A;  1KA7 A;  1BFI A;  1NZL A;  3CXL A;  4F5A A;  2OZO A;  4H34 A;  3VS4 A;  1MIL A;  2C9W A;  4A4B A;  3HIZ B;  1QCF A;  1Y57 A;  3BUX B;  1O4P A;  2VIF A;  1AOT F;  3K2M A;  2HDV A;  3M7F A;  4P9Z A;  2PNB A;  1OPK A;  2BBU A;  5HKW A;  5AXI A;  1A1A A;  3VS5 A;  1GHU A;  1KSW A;  4U17 A;  3GXW A;  1D1Z A;  4DGP A;  4E68 A;  2K7A B;  4X6S A;  2SHP A;  3NHN A;  3BUO B;  2PLD A;  3HCK A;  3MXY A;  1ZFP E;  1K9A A;  1TCE A;  1F1W A;  1O41 A;  4EIH A;  5KAZ A;  5GJH A;  2PNA A;  3TL0 A;  2H46 E;  3N8M A;  1O47 A;  1BLJ A;  3OB1 B;  1R1P A;  3VGO A;  4U1P A;  2EU0 A;  1BKM A;  2HUW A;  1FBV A;  1JYU A;  1R1S A;  1AB2 A;  2IZV A;  1AYD A;  1O4I A;  2EL8 A;  3PFV A;  4OHI A;  4LUE A;  1Z3K A;  1M27 A;  1Y1U A;  1BM2 A;  1O49 A;  1M61 A;  1AD5 A;  2FO0 A;  1O4H A;  2LCT A;  1O4D A;  3VS1 A;  1KC2 A;  1HCT B;  3VRZ A;  1NZV A;  2Y1N A;  2OQ1 A;  2GSB A;  5DC9 A;  1G83 A;  4L1B B;  2C0I A;  1X27 A;  5AUL A;  1OO4 A;  1BHH B;  1NRV A;  2XP1 A;  2DM0 A;  2DX0 A;  2QMS A;  2MQI A;  3MAZ A;  3VS2 A;  5DC4 A;  1H9O A;  1AYC A;  4NWF A;  3VRP A;  1YVL A;  4M4Z A;  4K45 A;  1GRI A;  5EG3 B;  1O4L A;  3T04 A;  1RJA A;  1D4T A;  3QWY A;  1FBZ A;  1BFJ A;  2EYV A;  2LNW A;  4GWF A;  1A1B A;  4QSY A;  4NWG A;  1O4F A;  4TZI A;  3VS6 A;  4JEG A;  5DF6 A;  2CI9 A;  1WQU A;  4DGX A;  1OO3 A;  3VS7 A;  4ROJ A;  2FCI A;  4XZ1 A;  3WA4 A;  2CBL A;  1FYR A;  1O4K A;  1BKL A;  1O43 A;  1LKL A;  1O4B A;  1CSY A;  1KA6 A;  2AOA A;  2DCR A;  2DLZ A;  1O4J A;  2ROR A;  1JWO A;  1O4Q A;  2MK2 A;  3UYO A;  1SHD A;  4GL9 E;  2CI8 A;  1A09 A;  2KNO A;  3BKB A;  3VRQ A;  1FHS A;  1UUR A;  3OB2 B;  4F59 A;  3N84 A;  1O4G A;  3BUW B;  3S8L A;  5DC0 B;  3ZNI A;  3S8N A;  2RMX A;  3S9K A;  2CRH A;  2EYZ A;  2MC1 A;  1BHH A;  2L6K A;  1O4O A;  5GJI A;  3IN8 A;  3PJP A;  4XZ0 A;  2RVF A;  4EY0 A;  1JYQ A;  2EYY A;  1YVH A;  2CS0 A;  2H5K A;  3CBL A;  4K2R A;  1A1E A;  1TZE E;  1B47 A;  1UUS A;  3VRO A;  1RPY A;  2RSY A;  2C0O A;  1IS0 A;  1SHA A;  1F2F A;  2GE9 A;  2H8H A;  3HHM B;  1RQQ C;  2PTK A;  5EHP A;  5D0J A;  1CSZ A;  3VRR A;  4FL3 A;  5EEQ A;  3GXX A;  3C7I A;  2Y3A B;  1LUM A;  4OHH A;  3IMD A;  3PQZ A;  1O45 A;  1O46 A;  2KK6 A;  4E93 A;  1AYA A;  3IN7 A;  3CD3 A;  1XA6 A;  2JYQ A;  1IJR A;  1QG1 E;  4GPL B;  1P13 A;  2SRC A;  2L3T A;  1SPR A;  1LUI A;  1O4M A;  1PIC A;  1FU5 A;  1OPL A;  2DLY A;  2HDX A;  3PLF B;  1BHF A;  1LUN A;  5I6V A;  4D8K A;  1O4C A;  3OVE A;  1D4W A;  3VS0 A;  1A1C A;  2LQN A;  1A07 A;  3MXC A;  3GQI B;  4A4C A;  3OV1 A;  2B3O A;  1SHB A;  2ECD A;  3VS3 A;  3QWX X;  1FU6 A;  4FL2 A;  4FBN A;  4OHE A;  5EEL A;  2AOB A;  4K44 A;  4P9V A;  3OP0 A;  2K79 B;  4OHD A;  3S8O A;  2ABL A;  2EO6 A;  2Y1M A;  1FMK A;  4LUD A;  3EAZ A;  1BF5 A;  3IMJ A;  3VRY A;  3PSK A;  5HKY A;  1BG1 A;  2C0T A;  1A08 A;  1JU5 A;  2PLE A;  1O4N A;  5J3X A;  4H1O A;  1LCK A;  1O4A A;  2AUG A;  5IBS A;  3N7Y A;  1LKK A;  4JE4 A;  1O44 A;  3VRN A;  1O4E A;  4JGH A;  3EAC A;  2HCK A;  3KFJ A;  1BLK A;  1SKJ A;  1I3Z A;  1CJ1 A;  1LUK A;  1O4R A;  5IBM A;  5HKZ A;  3US4 A;  5EHR A;  2EOB A; 
#chains in the Genus database with same CATH topology
 4K11 A;  2YSX A;  1X6C A;  1CWD L;  1AYB A;  1X0N A;  2IUG A;  1JYR A;  2EO3 A;  3CWG A;  4WWQ A;  1A81 A;  3PSJ A;  1CWE A;  2YU7 A;  3UF4 A;  1MW4 A;  1LCJ A;  2LNX A;  2DVJ A;  2IUI A;  2L4K A;  2HMH A;  2EKX A;  1HCS B;  2LQW A;  5CDW A;  4OHL A;  3PS5 A;  2CR4 A;  3BUM B;  3TKZ A;  1O48 A;  5BO4 A;  2MRK A;  1QAD A;  2CIA A;  2MRJ A;  4F5B A;  1BMB A;  2ETZ A;  1AOU F;  3BUN B;  1O42 A;  1R1Q A;  2IUH A;  1SPS A;  1KA7 A;  1BFI A;  1NZL A;  3CXL A;  4F5A A;  2OZO A;  4H34 A;  3VS4 A;  1MIL A;  2C9W A;  4A4B A;  3HIZ B;  1QCF A;  1Y57 A;  3BUX B;  1O4P A;  2VIF A;  1AOT F;  3K2M A;  2HDV A;  3M7F A;  4P9Z A;  2PNB A;  1OPK A;  2BBU A;  5HKW A;  5AXI A;  1A1A A;  3VS5 A;  1GHU A;  1KSW A;  4U17 A;  3GXW A;  1D1Z A;  4DGP A;  4E68 A;  2K7A B;  2KGY A;  4X6S A;  2SHP A;  3NHN A;  3BUO B;  2PLD A;  3HCK A;  3MXY A;  1ZFP E;  1K9A A;  1TCE A;  1F1W A;  1O41 A;  4EIH A;  5KAZ A;  5GJH A;  2PNA A;  3TL0 A;  2H46 E;  3N8M A;  1O47 A;  1BLJ A;  3OB1 B;  1R1P A;  3VGO A;  4U1P A;  2EU0 A;  1BKM A;  2HUW A;  1FBV A;  1JYU A;  1R1S A;  1AB2 A;  2IZV A;  1AYD A;  1O4I A;  2EL8 A;  3PFV A;  4OHI A;  4LUE A;  1Z3K A;  1M27 A;  1Y1U A;  1BM2 A;  1O49 A;  1M61 A;  1AD5 A;  2FO0 A;  1O4H A;  2LCT A;  1O4D A;  3VS1 A;  1KC2 A;  1HCT B;  3VRZ A;  1NZV A;  2Y1N A;  2OQ1 A;  2GSB A;  5DC9 A;  1G83 A;  4L1B B;  2C0I A;  1X27 A;  5AUL A;  1OO4 A;  1BHH B;  1NRV A;  2XP1 A;  2DM0 A;  2DX0 A;  2QMS A;  2MQI A;  3MAZ A;  3VS2 A;  5DC4 A;  1H9O A;  1AYC A;  4NWF A;  3VRP A;  1YVL A;  4M4Z A;  4K45 A;  1GRI A;  5EG3 B;  1O4L A;  3T04 A;  1RJA A;  1D4T A;  3QWY A;  1FBZ A;  3K2T A;  1BFJ A;  2EYV A;  2LNW A;  4GWF A;  1A1B A;  4QSY A;  4NWG A;  1O4F A;  4TZI A;  3VS6 A;  4JEG A;  5DF6 A;  2CI9 A;  1WQU A;  4DGX A;  1OO3 A;  3VS7 A;  4ROJ A;  2FCI A;  4XZ1 A;  3WA4 A;  2CBL A;  1FYR A;  1O4K A;  1BKL A;  1O43 A;  1LKL A;  1O4B A;  1CSY A;  1KA6 A;  2AOA A;  2DCR A;  2DLZ A;  1O4J A;  2ROR A;  1JWO A;  1O4Q A;  2MK2 A;  3UYO A;  1SHD A;  4GL9 E;  2CI8 A;  1A09 A;  2KNO A;  3BKB A;  3VRQ A;  1FHS A;  1UUR A;  3OB2 B;  4F59 A;  3N84 A;  1O4G A;  3BUW B;  3S8L A;  5DC0 B;  3ZNI A;  3S8N A;  2RMX A;  3S9K A;  2CRH A;  2EYZ A;  2MC1 A;  1BHH A;  2L6K A;  1O4O A;  5GJI A;  3IN8 A;  3PJP A;  4XZ0 A;  2RVF A;  4EY0 A;  1JYQ A;  2EYY A;  1YVH A;  2CS0 A;  2H5K A;  3CBL A;  4K2R A;  1A1E A;  1TZE E;  1B47 A;  1UUS A;  3VRO A;  1RPY A;  2RSY A;  2C0O A;  1IS0 A;  1SHA A;  1F2F A;  2GE9 A;  2H8H A;  3HHM B;  1RQQ C;  2PTK A;  5EHP A;  5D0J A;  1CSZ A;  3VRR A;  4FL3 A;  5EEQ A;  3GXX A;  3C7I A;  2Y3A B;  1LUM A;  4OHH A;  3IMD A;  3PQZ A;  1O45 A;  1O46 A;  2KK6 A;  4E93 A;  1AYA A;  3IN7 A;  3CD3 A;  1XA6 A;  2JYQ A;  1IJR A;  1QG1 E;  4GPL B;  1P13 A;  2SRC A;  2L3T A;  1SPR A;  1LUI A;  1O4M A;  1PIC A;  1FU5 A;  1OPL A;  2DLY A;  2HDX A;  3PLF B;  1BHF A;  1LUN A;  5I6V A;  4D8K A;  1O4C A;  3OVE A;  1D4W A;  3VS0 A;  1A1C A;  2LQN A;  1A07 A;  3MXC A;  3GQI B;  4A4C A;  3OV1 A;  2B3O A;  1SHB A;  2ECD A;  3VS3 A;  3QWX X;  1FU6 A;  4FL2 A;  4FBN A;  4OHE A;  5EEL A;  2AOB A;  4K44 A;  4P9V A;  3OP0 A;  2K79 B;  4OHD A;  3S8O A;  2ABL A;  2EO6 A;  2Y1M A;  1FMK A;  4LUD A;  3EAZ A;  1BF5 A;  3IMJ A;  3VRY A;  3PSK A;  5HKY A;  1BG1 A;  2C0T A;  1A08 A;  3LYV A;  1JU5 A;  2PLE A;  1O4N A;  5J3X A;  4H1O A;  1LCK A;  1O4A A;  2AUG A;  5IBS A;  3N7Y A;  1LKK A;  4JE4 A;  1O44 A;  3VRN A;  1O4E A;  2LRA A;  4JGH A;  3EAC A;  2HCK A;  3KFJ A;  1BLK A;  1SKJ A;  1I3Z A;  1CJ1 A;  1LUK A;  1O4R A;  5IBM A;  5HKZ A;  3US4 A;  5EHR A;  2EOB A; 
#chains in the Genus database with same CATH homology
 4K11 A;  2YSX A;  1X6C A;  1CWD L;  1AYB A;  1X0N A;  2IUG A;  1JYR A;  2EO3 A;  3CWG A;  4WWQ A;  1A81 A;  3PSJ A;  1CWE A;  2YU7 A;  3UF4 A;  1MW4 A;  1LCJ A;  2LNX A;  2DVJ A;  2IUI A;  2L4K A;  2HMH A;  2EKX A;  1HCS B;  2LQW A;  5CDW A;  4OHL A;  3PS5 A;  2CR4 A;  3BUM B;  3TKZ A;  1O48 A;  5BO4 A;  2MRK A;  1QAD A;  2CIA A;  2MRJ A;  4F5B A;  1BMB A;  2ETZ A;  1AOU F;  3BUN B;  1O42 A;  1R1Q A;  2IUH A;  1SPS A;  1KA7 A;  1BFI A;  1NZL A;  3CXL A;  4F5A A;  2OZO A;  4H34 A;  3VS4 A;  1MIL A;  2C9W A;  4A4B A;  3HIZ B;  1QCF A;  1Y57 A;  3BUX B;  1O4P A;  2VIF A;  1AOT F;  3K2M A;  2HDV A;  3M7F A;  4P9Z A;  2PNB A;  1OPK A;  2BBU A;  5HKW A;  5AXI A;  1A1A A;  3VS5 A;  1GHU A;  1KSW A;  4U17 A;  3GXW A;  1D1Z A;  4DGP A;  4E68 A;  2K7A B;  4X6S A;  2SHP A;  3NHN A;  3BUO B;  2PLD A;  3HCK A;  3MXY A;  1ZFP E;  1K9A A;  1TCE A;  1F1W A;  1O41 A;  4EIH A;  5KAZ A;  5GJH A;  2PNA A;  3TL0 A;  2H46 E;  3N8M A;  1O47 A;  1BLJ A;  3OB1 B;  1R1P A;  3VGO A;  4U1P A;  2EU0 A;  1BKM A;  2HUW A;  1FBV A;  1JYU A;  1R1S A;  1AB2 A;  2IZV A;  1AYD A;  1O4I A;  2EL8 A;  3PFV A;  4OHI A;  4LUE A;  1Z3K A;  1M27 A;  1Y1U A;  1BM2 A;  1O49 A;  1M61 A;  1AD5 A;  2FO0 A;  1O4H A;  2LCT A;  1O4D A;  3VS1 A;  1KC2 A;  1HCT B;  3VRZ A;  1NZV A;  2Y1N A;  2OQ1 A;  2GSB A;  5DC9 A;  1G83 A;  4L1B B;  2C0I A;  1X27 A;  5AUL A;  1OO4 A;  1BHH B;  1NRV A;  2XP1 A;  2DM0 A;  2DX0 A;  2QMS A;  2MQI A;  3MAZ A;  3VS2 A;  5DC4 A;  1H9O A;  1AYC A;  4NWF A;  3VRP A;  1YVL A;  4M4Z A;  4K45 A;  1GRI A;  5EG3 B;  1O4L A;  3T04 A;  1RJA A;  1D4T A;  3QWY A;  1FBZ A;  1BFJ A;  2EYV A;  2LNW A;  4GWF A;  1A1B A;  4QSY A;  4NWG A;  1O4F A;  4TZI A;  3VS6 A;  4JEG A;  5DF6 A;  2CI9 A;  1WQU A;  4DGX A;  1OO3 A;  3VS7 A;  4ROJ A;  2FCI A;  4XZ1 A;  3WA4 A;  2CBL A;  1FYR A;  1O4K A;  1BKL A;  1O43 A;  1LKL A;  1O4B A;  1CSY A;  1KA6 A;  2AOA A;  2DCR A;  2DLZ A;  1O4J A;  2ROR A;  1JWO A;  1O4Q A;  2MK2 A;  3UYO A;  1SHD A;  4GL9 E;  2CI8 A;  1A09 A;  2KNO A;  3BKB A;  3VRQ A;  1FHS A;  1UUR A;  3OB2 B;  4F59 A;  3N84 A;  1O4G A;  3BUW B;  3S8L A;  5DC0 B;  3ZNI A;  3S8N A;  2RMX A;  3S9K A;  2CRH A;  2EYZ A;  2MC1 A;  1BHH A;  2L6K A;  1O4O A;  5GJI A;  3IN8 A;  3PJP A;  4XZ0 A;  2RVF A;  4EY0 A;  1JYQ A;  2EYY A;  1YVH A;  2CS0 A;  2H5K A;  3CBL A;  4K2R A;  1A1E A;  1TZE E;  1B47 A;  1UUS A;  3VRO A;  1RPY A;  2RSY A;  2C0O A;  1IS0 A;  1SHA A;  1F2F A;  2GE9 A;  2H8H A;  3HHM B;  1RQQ C;  2PTK A;  5EHP A;  5D0J A;  1CSZ A;  3VRR A;  4FL3 A;  5EEQ A;  3GXX A;  3C7I A;  2Y3A B;  1LUM A;  4OHH A;  3IMD A;  3PQZ A;  1O45 A;  1O46 A;  2KK6 A;  4E93 A;  1AYA A;  3IN7 A;  3CD3 A;  1XA6 A;  2JYQ A;  1IJR A;  1QG1 E;  4GPL B;  1P13 A;  2SRC A;  2L3T A;  1SPR A;  1LUI A;  1O4M A;  1PIC A;  1FU5 A;  1OPL A;  2DLY A;  2HDX A;  3PLF B;  1BHF A;  1LUN A;  5I6V A;  4D8K A;  1O4C A;  3OVE A;  1D4W A;  3VS0 A;  1A1C A;  2LQN A;  1A07 A;  3MXC A;  3GQI B;  4A4C A;  3OV1 A;  2B3O A;  1SHB A;  2ECD A;  3VS3 A;  3QWX X;  1FU6 A;  4FL2 A;  4FBN A;  4OHE A;  5EEL A;  2AOB A;  4K44 A;  4P9V A;  3OP0 A;  2K79 B;  4OHD A;  3S8O A;  2ABL A;  2EO6 A;  2Y1M A;  1FMK A;  4LUD A;  3EAZ A;  1BF5 A;  3IMJ A;  3VRY A;  3PSK A;  5HKY A;  1BG1 A;  2C0T A;  1A08 A;  1JU5 A;  2PLE A;  1O4N A;  5J3X A;  4H1O A;  1LCK A;  1O4A A;  2AUG A;  5IBS A;  3N7Y A;  1LKK A;  4JE4 A;  1O44 A;  3VRN A;  1O4E A;  4JGH A;  3EAC A;  2HCK A;  3KFJ A;  1BLK A;  1SKJ A;  1I3Z A;  1CJ1 A;  1LUK A;  1O4R A;  5IBM A;  5HKZ A;  3US4 A;  5EHR A;  2EOB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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