1O43A

Crystal structure of sh2 in complex with ru82129.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o43A00
3UF4A 2CR4A 1AYAA 1GRIA 5EELA 2HDXA 1R1QA 3PSKA 3VS1A 1CSZA 1O4CA 5HKYA 1M27A 2B3OA 5I6VA 4NWGA 1TCEA 2CI9A 4P9VA 2EKXA 1FYRA 1QG1E 5BO4A 1SHDA 4OHHA 1A07A 1XA6A 4FL3A 3MXYA 2SHPA 2Y1MA 3PSJA 1O46A 2MRKA 1KC2A 2C0OA 1AYBA 1O44A 4NWFA 2GSBA 1O4RA 1RJAA 1A1BA 3PS5A 1LCKA 1LKLA 1JU5A 3US4A 5GJIA 1BFJA 4K11A 3N7YA 1JYQA 3VRRA 1BHFA 1GHUA 3S8OA 4F59A 1BHHA 2QMSA 5AXIA 2RMXA 1HCTB 2PNBA 4EIHA 4JGHA 1O4JA 2AOBA 4K45A 4LUDA 4F5BA 1FU5A 4FL2A 3OVEA 1AOTF 1A81A 2CI8A 4OHLA 1D4WA 1SPSA 1IS0A 1O49A 3T04A 5AULA 2EYZA 4H1OA 2MC1A 3HCKA 2CBLA 4K44A 3HHMB 3OB1B 3IMDA 2L6KA 4M4ZA 1O4DA 2PNAA 1FHSA 2PTKA 1Z3KA 4GWFA 3PQZA 5J3XA 2ABLA 2RORA 1O4FA 3BUOB 2BBUA 1BMBA 5EG3B 2PLEA 2L4KA 1BLJA 1RPYA 4H34A 1LUMA 4U1PA 3IN8A 4D8KA 3BUMB 2EO3A 5EEQA 2ECDA 1O4KA 4XZ0A 3VS6A 3GXWA 2CIAA 2YU7A 4XZ1A 1A09A 1BF5A 3OB2B 1O4AA 1LKKA 5HKWA 1IJRA 3M7FA 3VROA 2YSXA 4JE4A 1O4MA 2DX0A 1O41A 1A1AA 2Y3AB 1MILA 1LUIA 1NZVA 3KFJA 4ROJA 1O4EA 5GJHA 1SKJA 2HDVA 1BFIA 1HCSB 2HUWA 5EHRA 2KNOA 3OP0A 1BG1A 1O4OA 3ZNIA 5IBMA 3S9KA 1O4GA 1PICA 1Y57A 3VRPA 1B47A 1OPKA 2LCTA 2KK6A 1MW4A 3TL0A 1FU6A 4GL9E 1P13A 1O4BA 1QCFA 5DC0B 1TZEE 4TZIA 3MAZA 1OO4A 2RSYA 1O48A 1NRVA 1KA6A 2DLZA 1YVHA 1UURA 1A08A 3BUWB 1O42A 1O4NA 4OHDA 3HIZB 4X6SA 2IZVA 1F2FA 1X6CA 2JYQA 4LUEA 4FBNA 2FCIA 2CRHA 3VS2A 3VS4A 1R1SA 3BUXB 3QWYA 1AB2A 1FBVA 3GQIB 3UYOA 1SPRA 2DVJA 1AOUF 2LQNA 1O4LA 5DC4A 2K7AB 1O4QA 3S8LA 2MQIA 2EYVA 1OO3A 5D0JA 1O4PA 1BKLA 1BM2A 4GPLB 2HCKA 1F1WA 1CWEA 3CBLA 1KA7A 2RVFA 3VRNA 1CWDL 2K79B 4K2RA 1O43A 3S8NA 2LQWA 2SRCA 1SHAA 5CDWA 5DF6A 1O4IA 3QWXX 1SHBA 4E68A 4A4BA 2EYYA 1NZLA 1X0NA 4WWQA 4DGPA 1CSYA 2IUHA 2PLDA 2OZOA 1A1CA 4OHEA 1JYRA 1AD5A 3VS5A 1OPLA 2EU0A 2MRJA 4F5AA 4EY0A 1FBZA 1KSWA 2MK2A 2L3TA 2EL8A 3GXXA 2H5KA 2Y1NA 3VRQA 1ZFPE 3EAZA 2FO0A 3VGOA 4E93A 4A4CA 2DLYA 1R1PA 2C9WA 2DM0A 3N84A 3IN7A 1O4HA 4JEGA 3C7IA 3CD3A 2H46E 2HMHA 3WA4A 3MXCA 1FMKA 3OV1A 1BHHB 1AYDA 1I3ZA 1D4TA 1K9AA 1RQQC 3IMJA 1YVLA 2ETZA 3VRYA 1G83A 3CWGA 3BUNB 1QADA 2C0IA 2GE9A 2LNWA 1O45A 2DCRA 3VS3A 2C0TA 2LNXA 3NHNA 2H8HA 2IUIA 3TKZA 2VIFA 3VS0A 2AUGA 1WQUA 1UUSA 2OQ1A 1JYUA 2EOBA 1BLKA 1M61A 2AOAA 3PLFB 4DGXA 5DC9A 2XP1A 2EO6A 1AYCA 3EACA 1CJ1A 3K2MA 4P9ZA 3VS7A 1A1EA 2CS0A 5EHPA 5IBSA 1Y1UA 1LCJA 3PFVA 3CXLA 3PJPA 1LUNA 4U17A 1H9OA 1D1ZA 2IUGA 1LUKA 1JWOA 3VRZA 4OHIA 4QSYA 3N8MA 1BKMA 4L1BB 1X27A 5KAZA 1O47A 5HKZA 3BKBA
chains in the Genus database with same CATH superfamily
3UF4A 2CR4A 1AYAA 1GRIA 5EELA 2HDXA 1R1QA 3PSKA 3VS1A 1CSZA 1O4CA 5HKYA 1M27A 2B3OA 5I6VA 4NWGA 1TCEA 2CI9A 4P9VA 2EKXA 1FYRA 1QG1E 5BO4A 1SHDA 4OHHA 1A07A 1XA6A 4FL3A 3MXYA 2SHPA 2Y1MA 3PSJA 1O46A 2MRKA 1KC2A 2C0OA 1AYBA 1O44A 4NWFA 2GSBA 1O4RA 1RJAA 1A1BA 3PS5A 1LCKA 1LKLA 1JU5A 3US4A 5GJIA 1BFJA 4K11A 3N7YA 1JYQA 3VRRA 1BHFA 1GHUA 3S8OA 4F59A 1BHHA 2QMSA 5AXIA 2RMXA 1HCTB 2PNBA 4EIHA 4JGHA 1O4JA 2AOBA 4K45A 4LUDA 4F5BA 1FU5A 4FL2A 3OVEA 1AOTF 1A81A 2CI8A 4OHLA 1D4WA 1SPSA 1IS0A 1O49A 3T04A 5AULA 2EYZA 4H1OA 2MC1A 3HCKA 2CBLA 4K44A 3HHMB 3OB1B 3IMDA 2L6KA 4M4ZA 1O4DA 2PNAA 1FHSA 2PTKA 1Z3KA 4GWFA 3PQZA 5J3XA 2ABLA 2RORA 1O4FA 3BUOB 2BBUA 1BMBA 5EG3B 2PLEA 2L4KA 1BLJA 1RPYA 4H34A 1LUMA 4U1PA 3IN8A 4D8KA 3BUMB 2EO3A 5EEQA 2ECDA 1O4KA 4XZ0A 3VS6A 3GXWA 2CIAA 2YU7A 4XZ1A 1A09A 1BF5A 3OB2B 1O4AA 1LKKA 5HKWA 1IJRA 3M7FA 3VROA 2YSXA 4JE4A 1O4MA 2DX0A 1O41A 1A1AA 2Y3AB 1MILA 1LUIA 1NZVA 3KFJA 4ROJA 1O4EA 5GJHA 1SKJA 2HDVA 1BFIA 1HCSB 2HUWA 5EHRA 2KNOA 3OP0A 1BG1A 1O4OA 3ZNIA 5IBMA 3S9KA 1O4GA 1PICA 1Y57A 3VRPA 1B47A 1OPKA 2LCTA 2KK6A 1MW4A 3TL0A 1FU6A 4GL9E 1P13A 1O4BA 1QCFA 5DC0B 1TZEE 4TZIA 3MAZA 1OO4A 2RSYA 1O48A 1NRVA 1KA6A 2DLZA 1YVHA 1UURA 1A08A 3BUWB 1O42A 1O4NA 4OHDA 3HIZB 4X6SA 3K2TA 2IZVA 1F2FA 1X6CA 2JYQA 4LUEA 4FBNA 2FCIA 2CRHA 3VS2A 3VS4A 1R1SA 3BUXB 3QWYA 1AB2A 1FBVA 3GQIB 3UYOA 1SPRA 2DVJA 2KGYA 1AOUF 2LQNA 1O4LA 5DC4A 2K7AB 1O4QA 3S8LA 2MQIA 2EYVA 1OO3A 5D0JA 1O4PA 1BKLA 1BM2A 4GPLB 2HCKA 1F1WA 1CWEA 3CBLA 1KA7A 2RVFA 3VRNA 1CWDL 2K79B 4K2RA 1O43A 3S8NA 2LQWA 2SRCA 1SHAA 5CDWA 5DF6A 1O4IA 3QWXX 1SHBA 4E68A 4A4BA 2EYYA 1NZLA 1X0NA 4WWQA 4DGPA 1CSYA 2IUHA 2PLDA 2OZOA 1A1CA 4OHEA 1JYRA 1AD5A 3VS5A 1OPLA 2EU0A 2MRJA 4F5AA 4EY0A 1FBZA 1KSWA 2MK2A 2L3TA 2EL8A 3GXXA 2H5KA 2Y1NA 3VRQA 1ZFPE 3EAZA 2FO0A 3VGOA 4E93A 4A4CA 2DLYA 1R1PA 2C9WA 2DM0A 3N84A 2LRAA 3IN7A 1O4HA 4JEGA 3C7IA 3CD3A 2H46E 2HMHA 3WA4A 3MXCA 1FMKA 3OV1A 1BHHB 1AYDA 1I3ZA 1D4TA 1K9AA 1RQQC 3IMJA 1YVLA 2ETZA 3VRYA 1G83A 3CWGA 3BUNB 1QADA 2C0IA 2GE9A 2LNWA 1O45A 2DCRA 3VS3A 2C0TA 2LNXA 3NHNA 2H8HA 2IUIA 3TKZA 2VIFA 3VS0A 2AUGA 1WQUA 1UUSA 2OQ1A 1JYUA 2EOBA 1BLKA 1M61A 2AOAA 3PLFB 4DGXA 5DC9A 2XP1A 2EO6A 1AYCA 3EACA 1CJ1A 3K2MA 4P9ZA 3VS7A 1A1EA 2CS0A 5EHPA 5IBSA 1Y1UA 1LCJA 3PFVA 3CXLA 3PJPA 1LUNA 4U17A 1H9OA 1D1ZA 2IUGA 3LYVA 1LUKA 1JWOA 3VRZA 4OHIA 4QSYA 3N8MA 1BKMA 4L1BB 1X27A 5KAZA 1O47A 5HKZA 3BKBA
chains in the Genus database with same CATH topology
3UF4A 2CR4A 1AYAA 1GRIA 5EELA 2HDXA 1R1QA 3PSKA 3VS1A 1CSZA 1O4CA 5HKYA 1M27A 2B3OA 5I6VA 4NWGA 1TCEA 2CI9A 4P9VA 2EKXA 1FYRA 1QG1E 5BO4A 1SHDA 4OHHA 1A07A 1XA6A 4FL3A 3MXYA 2SHPA 2Y1MA 3PSJA 1O46A 2MRKA 1KC2A 2C0OA 1AYBA 1O44A 4NWFA 2GSBA 1O4RA 1RJAA 1A1BA 3PS5A 1LCKA 1LKLA 1JU5A 3US4A 5GJIA 1BFJA 4K11A 3N7YA 1JYQA 3VRRA 1BHFA 1GHUA 3S8OA 4F59A 1BHHA 2QMSA 5AXIA 2RMXA 1HCTB 2PNBA 4EIHA 4JGHA 1O4JA 2AOBA 4K45A 4LUDA 4F5BA 1FU5A 4FL2A 3OVEA 1AOTF 1A81A 2CI8A 4OHLA 1D4WA 1SPSA 1IS0A 1O49A 3T04A 5AULA 2EYZA 4H1OA 2MC1A 3HCKA 2CBLA 4K44A 3HHMB 3OB1B 3IMDA 2L6KA 4M4ZA 1O4DA 2PNAA 1FHSA 2PTKA 1Z3KA 4GWFA 3PQZA 5J3XA 2ABLA 2RORA 1O4FA 3BUOB 2BBUA 1BMBA 5EG3B 2PLEA 2L4KA 1BLJA 1RPYA 4H34A 1LUMA 4U1PA 3IN8A 4D8KA 3BUMB 2EO3A 5EEQA 2ECDA 1O4KA 4XZ0A 3VS6A 3GXWA 2CIAA 2YU7A 4XZ1A 1A09A 1BF5A 3OB2B 1O4AA 1LKKA 5HKWA 1IJRA 3M7FA 3VROA 2YSXA 4JE4A 1O4MA 2DX0A 1O41A 1A1AA 2Y3AB 1MILA 1LUIA 1NZVA 3KFJA 4ROJA 1O4EA 5GJHA 1SKJA 2HDVA 1BFIA 1HCSB 2HUWA 5EHRA 2KNOA 3OP0A 1BG1A 1O4OA 3ZNIA 5IBMA 3S9KA 1O4GA 1PICA 1Y57A 3VRPA 1B47A 1OPKA 2LCTA 2KK6A 1MW4A 3TL0A 1FU6A 4GL9E 1P13A 1O4BA 1QCFA 5DC0B 1TZEE 4TZIA 3MAZA 1OO4A 2RSYA 1O48A 1NRVA 1KA6A 2DLZA 1YVHA 1UURA 1A08A 3BUWB 1O42A 1O4NA 4OHDA 3HIZB 4X6SA 2IZVA 1F2FA 1X6CA 2JYQA 4LUEA 4FBNA 2FCIA 2CRHA 3VS2A 3VS4A 1R1SA 3BUXB 3QWYA 1AB2A 1FBVA 3GQIB 3UYOA 1SPRA 2DVJA 1AOUF 2LQNA 1O4LA 5DC4A 2K7AB 1O4QA 3S8LA 2MQIA 2EYVA 1OO3A 5D0JA 1O4PA 1BKLA 1BM2A 4GPLB 2HCKA 1F1WA 1CWEA 3CBLA 1KA7A 2RVFA 3VRNA 1CWDL 2K79B 4K2RA 1O43A 3S8NA 2LQWA 2SRCA 1SHAA 5CDWA 5DF6A 1O4IA 3QWXX 1SHBA 4E68A 4A4BA 2EYYA 1NZLA 1X0NA 4WWQA 4DGPA 1CSYA 2IUHA 2PLDA 2OZOA 1A1CA 4OHEA 1JYRA 1AD5A 3VS5A 1OPLA 2EU0A 2MRJA 4F5AA 4EY0A 1FBZA 1KSWA 2MK2A 2L3TA 2EL8A 3GXXA 2H5KA 2Y1NA 3VRQA 1ZFPE 3EAZA 2FO0A 3VGOA 4E93A 4A4CA 2DLYA 1R1PA 2C9WA 2DM0A 3N84A 3IN7A 1O4HA 4JEGA 3C7IA 3CD3A 2H46E 2HMHA 3WA4A 3MXCA 1FMKA 3OV1A 1BHHB 1AYDA 1I3ZA 1D4TA 1K9AA 1RQQC 3IMJA 1YVLA 2ETZA 3VRYA 1G83A 3CWGA 3BUNB 1QADA 2C0IA 2GE9A 2LNWA 1O45A 2DCRA 3VS3A 2C0TA 2LNXA 3NHNA 2H8HA 2IUIA 3TKZA 2VIFA 3VS0A 2AUGA 1WQUA 1UUSA 2OQ1A 1JYUA 2EOBA 1BLKA 1M61A 2AOAA 3PLFB 4DGXA 5DC9A 2XP1A 2EO6A 1AYCA 3EACA 1CJ1A 3K2MA 4P9ZA 3VS7A 1A1EA 2CS0A 5EHPA 5IBSA 1Y1UA 1LCJA 3PFVA 3CXLA 3PJPA 1LUNA 4U17A 1H9OA 1D1ZA 2IUGA 1LUKA 1JWOA 3VRZA 4OHIA 4QSYA 3N8MA 1BKMA 4L1BB 1X27A 5KAZA 1O47A 5HKZA 3BKBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UF4 A;  2CR4 A;  1AYA A;  1GRI A;  5EEL A;  2HDX A;  1R1Q A;  3PSK A;  3VS1 A;  1CSZ A;  1O4C A;  5HKY A;  1M27 A;  2B3O A;  5I6V A;  4NWG A;  1TCE A;  2CI9 A;  4P9V A;  2EKX A;  1FYR A;  1QG1 E;  5BO4 A;  1SHD A;  4OHH A;  1A07 A;  1XA6 A;  4FL3 A;  3MXY A;  2SHP A;  2Y1M A;  3PSJ A;  1O46 A;  2MRK A;  1KC2 A;  2C0O A;  1AYB A;  1O44 A;  4NWF A;  2GSB A;  1O4R A;  1RJA A;  1A1B A;  3PS5 A;  1LCK A;  1LKL A;  1JU5 A;  3US4 A;  5GJI A;  1BFJ A;  4K11 A;  3N7Y A;  1JYQ A;  3VRR A;  1BHF A;  1GHU A;  3S8O A;  4F59 A;  1BHH A;  2QMS A;  5AXI A;  2RMX A;  1HCT B;  2PNB A;  4EIH A;  4JGH A;  1O4J A;  2AOB A;  4K45 A;  4LUD A;  4F5B A;  1FU5 A;  4FL2 A;  3OVE A;  1AOT F;  1A81 A;  2CI8 A;  4OHL A;  1D4W A;  1SPS A;  1IS0 A;  1O49 A;  3T04 A;  5AUL A;  2EYZ A;  4H1O A;  2MC1 A;  3HCK A;  2CBL A;  4K44 A;  3HHM B;  3OB1 B;  3IMD A;  2L6K A;  4M4Z A;  1O4D A;  2PNA A;  1FHS A;  2PTK A;  1Z3K A;  4GWF A;  3PQZ A;  5J3X A;  2ABL A;  2ROR A;  1O4F A;  3BUO B;  2BBU A;  1BMB A;  5EG3 B;  2PLE A;  2L4K A;  1BLJ A;  1RPY A;  4H34 A;  1LUM A;  4U1P A;  3IN8 A;  4D8K A;  3BUM B;  2EO3 A;  5EEQ A;  2ECD A;  1O4K A;  4XZ0 A;  3VS6 A;  3GXW A;  2CIA A;  2YU7 A;  4XZ1 A;  1A09 A;  1BF5 A;  3OB2 B;  1O4A A;  1LKK A;  5HKW A;  1IJR A;  3M7F A;  3VRO A;  2YSX A;  4JE4 A;  1O4M A;  2DX0 A;  1O41 A;  1A1A A;  2Y3A B;  1MIL A;  1LUI A;  1NZV A;  3KFJ A;  4ROJ A;  1O4E A;  5GJH A;  1SKJ A;  2HDV A;  1BFI A;  1HCS B;  2HUW A;  5EHR A;  2KNO A;  3OP0 A;  1BG1 A;  1O4O A;  3ZNI A;  5IBM A;  3S9K A;  1O4G A;  1PIC A;  1Y57 A;  3VRP A;  1B47 A;  1OPK A;  2LCT A;  2KK6 A;  1MW4 A;  3TL0 A;  1FU6 A;  4GL9 E;  1P13 A;  1O4B A;  1QCF A;  5DC0 B;  1TZE E;  4TZI A;  3MAZ A;  1OO4 A;  2RSY A;  1O48 A;  1NRV A;  1KA6 A;  2DLZ A;  1YVH A;  1UUR A;  1A08 A;  3BUW B;  1O42 A;  1O4N A;  4OHD A;  3HIZ B;  4X6S A;  2IZV A;  1F2F A;  1X6C A;  2JYQ A;  4LUE A;  4FBN A;  2FCI A;  2CRH A;  3VS2 A;  3VS4 A;  1R1S A;  3BUX B;  3QWY A;  1AB2 A;  1FBV A;  3GQI B;  3UYO A;  1SPR A;  2DVJ A;  1AOU F;  2LQN A;  1O4L A;  5DC4 A;  2K7A B;  1O4Q A;  3S8L A;  2MQI A;  2EYV A;  1OO3 A;  5D0J A;  1O4P A;  1BKL A;  1BM2 A;  4GPL B;  2HCK A;  1F1W A;  1CWE A;  3CBL A;  1KA7 A;  2RVF A;  3VRN A;  1CWD L;  2K79 B;  4K2R A;  1O43 A;  3S8N A;  2LQW A;  2SRC A;  1SHA A;  5CDW A;  5DF6 A;  1O4I A;  3QWX X;  1SHB A;  4E68 A;  4A4B A;  2EYY A;  1NZL A;  1X0N A;  4WWQ A;  4DGP A;  1CSY A;  2IUH A;  2PLD A;  2OZO A;  1A1C A;  4OHE A;  1JYR A;  1AD5 A;  3VS5 A;  1OPL A;  2EU0 A;  2MRJ A;  4F5A A;  4EY0 A;  1FBZ A;  1KSW A;  2MK2 A;  2L3T A;  2EL8 A;  3GXX A;  2H5K A;  2Y1N A;  3VRQ A;  1ZFP E;  3EAZ A;  2FO0 A;  3VGO A;  4E93 A;  4A4C A;  2DLY A;  1R1P A;  2C9W A;  2DM0 A;  3N84 A;  3IN7 A;  1O4H A;  4JEG A;  3C7I A;  3CD3 A;  2H46 E;  2HMH A;  3WA4 A;  3MXC A;  1FMK A;  3OV1 A;  1BHH B;  1AYD A;  1I3Z A;  1D4T A;  1K9A A;  1RQQ C;  3IMJ A;  1YVL A;  2ETZ A;  3VRY A;  1G83 A;  3CWG A;  3BUN B;  1QAD A;  2C0I A;  2GE9 A;  2LNW A;  1O45 A;  2DCR A;  3VS3 A;  2C0T A;  2LNX A;  3NHN A;  2H8H A;  2IUI A;  3TKZ A;  2VIF A;  3VS0 A;  2AUG A;  1WQU A;  1UUS A;  2OQ1 A;  1JYU A;  2EOB A;  1BLK A;  1M61 A;  2AOA A;  3PLF B;  4DGX A;  5DC9 A;  2XP1 A;  2EO6 A;  1AYC A;  3EAC A;  1CJ1 A;  3K2M A;  4P9Z A;  3VS7 A;  1A1E A;  2CS0 A;  5EHP A;  5IBS A;  1Y1U A;  1LCJ A;  3PFV A;  3CXL A;  3PJP A;  1LUN A;  4U17 A;  1H9O A;  1D1Z A;  2IUG A;  1LUK A;  1JWO A;  3VRZ A;  4OHI A;  4QSY A;  3N8M A;  1BKM A;  4L1B B;  1X27 A;  5KAZ A;  1O47 A;  5HKZ A;  3BKB A; 
#chains in the Genus database with same CATH topology
 3UF4 A;  2CR4 A;  1AYA A;  1GRI A;  5EEL A;  2HDX A;  1R1Q A;  3PSK A;  3VS1 A;  1CSZ A;  1O4C A;  5HKY A;  1M27 A;  2B3O A;  5I6V A;  4NWG A;  1TCE A;  2CI9 A;  4P9V A;  2EKX A;  1FYR A;  1QG1 E;  5BO4 A;  1SHD A;  4OHH A;  1A07 A;  1XA6 A;  4FL3 A;  3MXY A;  2SHP A;  2Y1M A;  3PSJ A;  1O46 A;  2MRK A;  1KC2 A;  2C0O A;  1AYB A;  1O44 A;  4NWF A;  2GSB A;  1O4R A;  1RJA A;  1A1B A;  3PS5 A;  1LCK A;  1LKL A;  1JU5 A;  3US4 A;  5GJI A;  1BFJ A;  4K11 A;  3N7Y A;  1JYQ A;  3VRR A;  1BHF A;  1GHU A;  3S8O A;  4F59 A;  1BHH A;  2QMS A;  5AXI A;  2RMX A;  1HCT B;  2PNB A;  4EIH A;  4JGH A;  1O4J A;  2AOB A;  4K45 A;  4LUD A;  4F5B A;  1FU5 A;  4FL2 A;  3OVE A;  1AOT F;  1A81 A;  2CI8 A;  4OHL A;  1D4W A;  1SPS A;  1IS0 A;  1O49 A;  3T04 A;  5AUL A;  2EYZ A;  4H1O A;  2MC1 A;  3HCK A;  2CBL A;  4K44 A;  3HHM B;  3OB1 B;  3IMD A;  2L6K A;  4M4Z A;  1O4D A;  2PNA A;  1FHS A;  2PTK A;  1Z3K A;  4GWF A;  3PQZ A;  5J3X A;  2ABL A;  2ROR A;  1O4F A;  3BUO B;  2BBU A;  1BMB A;  5EG3 B;  2PLE A;  2L4K A;  1BLJ A;  1RPY A;  4H34 A;  1LUM A;  4U1P A;  3IN8 A;  4D8K A;  3BUM B;  2EO3 A;  5EEQ A;  2ECD A;  1O4K A;  4XZ0 A;  3VS6 A;  3GXW A;  2CIA A;  2YU7 A;  4XZ1 A;  1A09 A;  1BF5 A;  3OB2 B;  1O4A A;  1LKK A;  5HKW A;  1IJR A;  3M7F A;  3VRO A;  2YSX A;  4JE4 A;  1O4M A;  2DX0 A;  1O41 A;  1A1A A;  2Y3A B;  1MIL A;  1LUI A;  1NZV A;  3KFJ A;  4ROJ A;  1O4E A;  5GJH A;  1SKJ A;  2HDV A;  1BFI A;  1HCS B;  2HUW A;  5EHR A;  2KNO A;  3OP0 A;  1BG1 A;  1O4O A;  3ZNI A;  5IBM A;  3S9K A;  1O4G A;  1PIC A;  1Y57 A;  3VRP A;  1B47 A;  1OPK A;  2LCT A;  2KK6 A;  1MW4 A;  3TL0 A;  1FU6 A;  4GL9 E;  1P13 A;  1O4B A;  1QCF A;  5DC0 B;  1TZE E;  4TZI A;  3MAZ A;  1OO4 A;  2RSY A;  1O48 A;  1NRV A;  1KA6 A;  2DLZ A;  1YVH A;  1UUR A;  1A08 A;  3BUW B;  1O42 A;  1O4N A;  4OHD A;  3HIZ B;  4X6S A;  3K2T A;  2IZV A;  1F2F A;  1X6C A;  2JYQ A;  4LUE A;  4FBN A;  2FCI A;  2CRH A;  3VS2 A;  3VS4 A;  1R1S A;  3BUX B;  3QWY A;  1AB2 A;  1FBV A;  3GQI B;  3UYO A;  1SPR A;  2DVJ A;  2KGY A;  1AOU F;  2LQN A;  1O4L A;  5DC4 A;  2K7A B;  1O4Q A;  3S8L A;  2MQI A;  2EYV A;  1OO3 A;  5D0J A;  1O4P A;  1BKL A;  1BM2 A;  4GPL B;  2HCK A;  1F1W A;  1CWE A;  3CBL A;  1KA7 A;  2RVF A;  3VRN A;  1CWD L;  2K79 B;  4K2R A;  1O43 A;  3S8N A;  2LQW A;  2SRC A;  1SHA A;  5CDW A;  5DF6 A;  1O4I A;  3QWX X;  1SHB A;  4E68 A;  4A4B A;  2EYY A;  1NZL A;  1X0N A;  4WWQ A;  4DGP A;  1CSY A;  2IUH A;  2PLD A;  2OZO A;  1A1C A;  4OHE A;  1JYR A;  1AD5 A;  3VS5 A;  1OPL A;  2EU0 A;  2MRJ A;  4F5A A;  4EY0 A;  1FBZ A;  1KSW A;  2MK2 A;  2L3T A;  2EL8 A;  3GXX A;  2H5K A;  2Y1N A;  3VRQ A;  1ZFP E;  3EAZ A;  2FO0 A;  3VGO A;  4E93 A;  4A4C A;  2DLY A;  1R1P A;  2C9W A;  2DM0 A;  3N84 A;  2LRA A;  3IN7 A;  1O4H A;  4JEG A;  3C7I A;  3CD3 A;  2H46 E;  2HMH A;  3WA4 A;  3MXC A;  1FMK A;  3OV1 A;  1BHH B;  1AYD A;  1I3Z A;  1D4T A;  1K9A A;  1RQQ C;  3IMJ A;  1YVL A;  2ETZ A;  3VRY A;  1G83 A;  3CWG A;  3BUN B;  1QAD A;  2C0I A;  2GE9 A;  2LNW A;  1O45 A;  2DCR A;  3VS3 A;  2C0T A;  2LNX A;  3NHN A;  2H8H A;  2IUI A;  3TKZ A;  2VIF A;  3VS0 A;  2AUG A;  1WQU A;  1UUS A;  2OQ1 A;  1JYU A;  2EOB A;  1BLK A;  1M61 A;  2AOA A;  3PLF B;  4DGX A;  5DC9 A;  2XP1 A;  2EO6 A;  1AYC A;  3EAC A;  1CJ1 A;  3K2M A;  4P9Z A;  3VS7 A;  1A1E A;  2CS0 A;  5EHP A;  5IBS A;  1Y1U A;  1LCJ A;  3PFV A;  3CXL A;  3PJP A;  1LUN A;  4U17 A;  1H9O A;  1D1Z A;  2IUG A;  3LYV A;  1LUK A;  1JWO A;  3VRZ A;  4OHI A;  4QSY A;  3N8M A;  1BKM A;  4L1B B;  1X27 A;  5KAZ A;  1O47 A;  5HKZ A;  3BKB A; 
#chains in the Genus database with same CATH homology
 3UF4 A;  2CR4 A;  1AYA A;  1GRI A;  5EEL A;  2HDX A;  1R1Q A;  3PSK A;  3VS1 A;  1CSZ A;  1O4C A;  5HKY A;  1M27 A;  2B3O A;  5I6V A;  4NWG A;  1TCE A;  2CI9 A;  4P9V A;  2EKX A;  1FYR A;  1QG1 E;  5BO4 A;  1SHD A;  4OHH A;  1A07 A;  1XA6 A;  4FL3 A;  3MXY A;  2SHP A;  2Y1M A;  3PSJ A;  1O46 A;  2MRK A;  1KC2 A;  2C0O A;  1AYB A;  1O44 A;  4NWF A;  2GSB A;  1O4R A;  1RJA A;  1A1B A;  3PS5 A;  1LCK A;  1LKL A;  1JU5 A;  3US4 A;  5GJI A;  1BFJ A;  4K11 A;  3N7Y A;  1JYQ A;  3VRR A;  1BHF A;  1GHU A;  3S8O A;  4F59 A;  1BHH A;  2QMS A;  5AXI A;  2RMX A;  1HCT B;  2PNB A;  4EIH A;  4JGH A;  1O4J A;  2AOB A;  4K45 A;  4LUD A;  4F5B A;  1FU5 A;  4FL2 A;  3OVE A;  1AOT F;  1A81 A;  2CI8 A;  4OHL A;  1D4W A;  1SPS A;  1IS0 A;  1O49 A;  3T04 A;  5AUL A;  2EYZ A;  4H1O A;  2MC1 A;  3HCK A;  2CBL A;  4K44 A;  3HHM B;  3OB1 B;  3IMD A;  2L6K A;  4M4Z A;  1O4D A;  2PNA A;  1FHS A;  2PTK A;  1Z3K A;  4GWF A;  3PQZ A;  5J3X A;  2ABL A;  2ROR A;  1O4F A;  3BUO B;  2BBU A;  1BMB A;  5EG3 B;  2PLE A;  2L4K A;  1BLJ A;  1RPY A;  4H34 A;  1LUM A;  4U1P A;  3IN8 A;  4D8K A;  3BUM B;  2EO3 A;  5EEQ A;  2ECD A;  1O4K A;  4XZ0 A;  3VS6 A;  3GXW A;  2CIA A;  2YU7 A;  4XZ1 A;  1A09 A;  1BF5 A;  3OB2 B;  1O4A A;  1LKK A;  5HKW A;  1IJR A;  3M7F A;  3VRO A;  2YSX A;  4JE4 A;  1O4M A;  2DX0 A;  1O41 A;  1A1A A;  2Y3A B;  1MIL A;  1LUI A;  1NZV A;  3KFJ A;  4ROJ A;  1O4E A;  5GJH A;  1SKJ A;  2HDV A;  1BFI A;  1HCS B;  2HUW A;  5EHR A;  2KNO A;  3OP0 A;  1BG1 A;  1O4O A;  3ZNI A;  5IBM A;  3S9K A;  1O4G A;  1PIC A;  1Y57 A;  3VRP A;  1B47 A;  1OPK A;  2LCT A;  2KK6 A;  1MW4 A;  3TL0 A;  1FU6 A;  4GL9 E;  1P13 A;  1O4B A;  1QCF A;  5DC0 B;  1TZE E;  4TZI A;  3MAZ A;  1OO4 A;  2RSY A;  1O48 A;  1NRV A;  1KA6 A;  2DLZ A;  1YVH A;  1UUR A;  1A08 A;  3BUW B;  1O42 A;  1O4N A;  4OHD A;  3HIZ B;  4X6S A;  2IZV A;  1F2F A;  1X6C A;  2JYQ A;  4LUE A;  4FBN A;  2FCI A;  2CRH A;  3VS2 A;  3VS4 A;  1R1S A;  3BUX B;  3QWY A;  1AB2 A;  1FBV A;  3GQI B;  3UYO A;  1SPR A;  2DVJ A;  1AOU F;  2LQN A;  1O4L A;  5DC4 A;  2K7A B;  1O4Q A;  3S8L A;  2MQI A;  2EYV A;  1OO3 A;  5D0J A;  1O4P A;  1BKL A;  1BM2 A;  4GPL B;  2HCK A;  1F1W A;  1CWE A;  3CBL A;  1KA7 A;  2RVF A;  3VRN A;  1CWD L;  2K79 B;  4K2R A;  1O43 A;  3S8N A;  2LQW A;  2SRC A;  1SHA A;  5CDW A;  5DF6 A;  1O4I A;  3QWX X;  1SHB A;  4E68 A;  4A4B A;  2EYY A;  1NZL A;  1X0N A;  4WWQ A;  4DGP A;  1CSY A;  2IUH A;  2PLD A;  2OZO A;  1A1C A;  4OHE A;  1JYR A;  1AD5 A;  3VS5 A;  1OPL A;  2EU0 A;  2MRJ A;  4F5A A;  4EY0 A;  1FBZ A;  1KSW A;  2MK2 A;  2L3T A;  2EL8 A;  3GXX A;  2H5K A;  2Y1N A;  3VRQ A;  1ZFP E;  3EAZ A;  2FO0 A;  3VGO A;  4E93 A;  4A4C A;  2DLY A;  1R1P A;  2C9W A;  2DM0 A;  3N84 A;  3IN7 A;  1O4H A;  4JEG A;  3C7I A;  3CD3 A;  2H46 E;  2HMH A;  3WA4 A;  3MXC A;  1FMK A;  3OV1 A;  1BHH B;  1AYD A;  1I3Z A;  1D4T A;  1K9A A;  1RQQ C;  3IMJ A;  1YVL A;  2ETZ A;  3VRY A;  1G83 A;  3CWG A;  3BUN B;  1QAD A;  2C0I A;  2GE9 A;  2LNW A;  1O45 A;  2DCR A;  3VS3 A;  2C0T A;  2LNX A;  3NHN A;  2H8H A;  2IUI A;  3TKZ A;  2VIF A;  3VS0 A;  2AUG A;  1WQU A;  1UUS A;  2OQ1 A;  1JYU A;  2EOB A;  1BLK A;  1M61 A;  2AOA A;  3PLF B;  4DGX A;  5DC9 A;  2XP1 A;  2EO6 A;  1AYC A;  3EAC A;  1CJ1 A;  3K2M A;  4P9Z A;  3VS7 A;  1A1E A;  2CS0 A;  5EHP A;  5IBS A;  1Y1U A;  1LCJ A;  3PFV A;  3CXL A;  3PJP A;  1LUN A;  4U17 A;  1H9O A;  1D1Z A;  2IUG A;  1LUK A;  1JWO A;  3VRZ A;  4OHI A;  4QSY A;  3N8M A;  1BKM A;  4L1B B;  1X27 A;  5KAZ A;  1O47 A;  5HKZ A;  3BKB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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