2IUGA

Crystal structure of the pi3-kinase p85 n-terminal sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
110
structure length
110
Chain Sequence
NNMSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
pubmed doi rcsb
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
molecule tags Transferase
source organism Homo sapiens
total genus 29
structure length 110
sequence length 110
ec nomenclature
pdb deposition date 2006-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2iugA00
4GPLB 1FYRA 2B3OA 2PNAA 3GXWA 1OO4A 3MAZA 1SHAA 4F59A 1O4AA 1FHSA 3ZNIA 5I6VA 3QWYA 2RVFA 1JYUA 1GHUA 4DGXA 3PQZA 1IJRA 1AD5A 1O4CA 1Y1UA 4OHIA 3VRPA 3N8MA 1BHHA 2EYZA 1LUKA 2PTKA 1AB2A 2C9WA 1X6CA 2LQWA 1CSYA 1YVHA 1IS0A 1O46A 1BKLA 1M27A 1KC2A 1R1QA 2MRJA 1CWDL 2IUIA 2PLEA 5AULA 1CSZA 3PSJA 4A4CA 5DC9A 4XZ1A 1PICA 2HDXA 3S8OA 4K45A 3VS1A 3VRZA 3M7FA 3BUWB 1KA7A 1A1EA 1BKMA 2EOBA 3OB1B 2QMSA 2DVJA 2XP1A 4TZIA 1D1ZA 5IBSA 5GJIA 1A1AA 1O4FA 4LUDA 3S9KA 2HCKA 2LNWA 3VRQA 3MXCA 2C0OA 3VS0A 3VS3A 2OQ1A 4XZ0A 1I3ZA 5DC0B 3VS4A 2C0TA 1M61A 3EAZA 1AYAA 1ZFPE 5EHPA 5CDWA 2K7AB 2YSXA 1UURA 2HUWA 1FU6A 1O4HA 4NWGA 3VRRA 1QCFA 1CJ1A 1SHBA 3US4A 1O4LA 2AUGA 2EKXA 1AYBA 2L6KA 1JU5A 1JYQA 2Y1NA 1AYCA 2MQIA 1G83A 4OHDA 4K44A 3GQIB 1O41A 3MXYA 1JWOA 3IMDA 4JE4A 4EIHA 1O4PA 4JGHA 3HIZB 5EHRA 1O4NA 4P9ZA 4OHLA 2YU7A 5HKZA 3UYOA 4FL2A 5AXIA 1O4GA 4A4BA 3CBLA 2AOBA 1RQQC 1O4MA 1QADA 1O4BA 3GXXA 2MC1A 1JYRA 1YVLA 1O42A 3BUOB 5J3XA 2FO0A 2PNBA 3CWGA 1F1WA 3S8NA 3OP0A 2OZOA 2EYVA 1D4TA 4H34A 2L4KA 2KK6A 2L3TA 3PLFB 3BUNB 1BHHB 1LKKA 1AOTF 3PS5A 4OHEA 1K9AA 2Y3AB 2LCTA 3KFJA 1OPLA 1SPRA 3UF4A 1BLKA 1OPKA 4GWFA 2EO6A 1O47A 3VS6A 5EG3B 1RPYA 2H8HA 2SHPA 3CXLA 5KAZA 1TZEE 1A08A 2CR4A 4DGPA 4ROJA 1LCKA 3C7IA 2JYQA 1CWEA 1BG1A 3N84A 1A07A 2H46E 1MILA 4LUEA 1RJAA 3HHMB 3VRYA 2H5KA 4NWFA 3NHNA 1LUIA 2DCRA 4M4ZA 4F5BA 2VIFA 3TL0A 1FBVA 2IZVA 3S8LA 5IBMA 2RMXA 2Y1MA 1GRIA 1NRVA 5DF6A 1AYDA 3BKBA 3PSKA 4K11A 5GJHA 3TKZA 5DC4A 1QG1E 3N7YA 4OHHA 4EY0A 4D8KA 2ETZA 1Z3KA 3VGOA 1O4KA 1FU5A 1O4JA 4L1BB 1KA6A 1FBZA 1OO3A 4GL9E 5HKWA 2CS0A 1WQUA 3VS7A 1O4OA 2ABLA 2CBLA 1BMBA 1O4IA 2HMHA 1NZLA 3VS2A 1KSWA 1X0NA 2EO3A 2C0IA 1O4RA 1HCTB 4K2RA 1NZVA 3BUXB 1MW4A 1A09A 4FL3A 1LKLA 1BFJA 2RORA 1BFIA 1O45A 2MK2A 3PFVA 3OV1A 3BUMB 4QSYA 5BO4A 4JEGA 5EEQA 2CI8A 1Y57A 3CD3A 1XA6A 2MRKA 1HCSB 4X6SA 1LUNA 3HCKA 1BF5A 1O44A 1P13A 1TCEA 1B47A 1O4DA 3OB2B 2FCIA 2EYYA 2RSYA 4E93A 2KNOA 1BM2A 1R1PA 1UUSA 2HDVA 2BBUA 1SKJA 3OVEA 1R1SA 5EELA 2AOAA 1O4EA 4U17A 3K2MA 2PLDA 2EU0A 2DLYA 2DX0A 4H1OA 2ECDA 1LUMA 4P9VA 1SPSA 1D4WA 3WA4A 3IN7A 1H9OA 3IN8A 2DLZA 1X27A 3VROA 2CIAA 2GE9A 2DM0A 2LQNA 5D0JA 3IMJA 1A1CA 4WWQA 2CI9A 1O49A 4U1PA 1O48A 2CRHA 3PJPA 1BHFA 3QWXX 3VS5A 3EACA 2SRCA 1A1BA 4E68A 2GSBA 2K79B 1O43A 4F5AA 2LNXA 1O4QA 3T04A 4FBNA 3VRNA 2EL8A 5HKYA 1A81A 1AOUF 2IUHA 1FMKA 1F2FA 2IUGA 1BLJA 1LCJA 1SHDA
chains in the Genus database with same CATH superfamily
4GPLB 1FYRA 2B3OA 2PNAA 3GXWA 1OO4A 3MAZA 1SHAA 4F59A 1O4AA 1FHSA 3ZNIA 5I6VA 3QWYA 2RVFA 1JYUA 1GHUA 4DGXA 3PQZA 1IJRA 1AD5A 1O4CA 1Y1UA 4OHIA 3VRPA 3N8MA 1BHHA 2EYZA 1LUKA 2PTKA 1AB2A 2C9WA 1X6CA 2LQWA 1CSYA 1YVHA 1IS0A 1O46A 1BKLA 1M27A 1KC2A 1R1QA 2MRJA 1CWDL 2IUIA 2PLEA 5AULA 1CSZA 3PSJA 4A4CA 5DC9A 4XZ1A 1PICA 2HDXA 3S8OA 4K45A 3VS1A 3VRZA 3M7FA 3BUWB 1KA7A 1A1EA 1BKMA 2EOBA 3OB1B 2QMSA 2DVJA 2XP1A 4TZIA 1D1ZA 5IBSA 5GJIA 1A1AA 1O4FA 4LUDA 3S9KA 2HCKA 2LNWA 3VRQA 3MXCA 2C0OA 3VS0A 3VS3A 2OQ1A 4XZ0A 1I3ZA 5DC0B 3VS4A 2C0TA 1M61A 3EAZA 1AYAA 1ZFPE 5EHPA 5CDWA 2K7AB 2YSXA 1UURA 2HUWA 1FU6A 1O4HA 4NWGA 3VRRA 1QCFA 1CJ1A 1SHBA 3US4A 1O4LA 2AUGA 2EKXA 1AYBA 2L6KA 1JU5A 1JYQA 2Y1NA 1AYCA 2MQIA 1G83A 4OHDA 4K44A 3GQIB 1O41A 3MXYA 1JWOA 3IMDA 4JE4A 4EIHA 1O4PA 4JGHA 3HIZB 5EHRA 1O4NA 4P9ZA 4OHLA 2YU7A 5HKZA 3UYOA 4FL2A 5AXIA 1O4GA 4A4BA 3CBLA 2AOBA 1RQQC 1O4MA 1QADA 1O4BA 3GXXA 2MC1A 1JYRA 1YVLA 1O42A 3BUOB 5J3XA 2FO0A 2PNBA 3CWGA 1F1WA 3S8NA 3OP0A 2OZOA 2EYVA 1D4TA 4H34A 2L4KA 2KK6A 2L3TA 3PLFB 3BUNB 1BHHB 1LKKA 1AOTF 3PS5A 4OHEA 1K9AA 2Y3AB 2LCTA 3KFJA 1OPLA 1SPRA 3LYVA 3UF4A 1BLKA 1OPKA 4GWFA 2EO6A 1O47A 3VS6A 5EG3B 1RPYA 2H8HA 2SHPA 3CXLA 5KAZA 1TZEE 1A08A 2CR4A 4DGPA 4ROJA 1LCKA 3C7IA 2JYQA 1CWEA 1BG1A 3N84A 1A07A 2H46E 1MILA 4LUEA 1RJAA 3HHMB 3VRYA 2H5KA 4NWFA 3NHNA 1LUIA 2DCRA 4M4ZA 4F5BA 2VIFA 3TL0A 1FBVA 2IZVA 3S8LA 5IBMA 2RMXA 2Y1MA 1GRIA 1NRVA 5DF6A 1AYDA 3BKBA 3PSKA 4K11A 5GJHA 3TKZA 5DC4A 1QG1E 3N7YA 4OHHA 4EY0A 4D8KA 2ETZA 1Z3KA 3VGOA 1O4KA 1FU5A 1O4JA 4L1BB 1KA6A 1FBZA 1OO3A 2LRAA 4GL9E 5HKWA 2CS0A 1WQUA 3VS7A 1O4OA 2ABLA 2CBLA 1BMBA 1O4IA 2HMHA 1NZLA 3VS2A 1KSWA 1X0NA 2EO3A 2C0IA 1O4RA 1HCTB 4K2RA 1NZVA 3BUXB 1MW4A 1A09A 4FL3A 1LKLA 1BFJA 2RORA 1BFIA 1O45A 2MK2A 3PFVA 3OV1A 3BUMB 4QSYA 5BO4A 4JEGA 5EEQA 2CI8A 1Y57A 3CD3A 1XA6A 2MRKA 2KGYA 1HCSB 4X6SA 1LUNA 3HCKA 1BF5A 1O44A 1P13A 1TCEA 1B47A 1O4DA 3OB2B 2FCIA 2EYYA 2RSYA 4E93A 2KNOA 1BM2A 1R1PA 1UUSA 2HDVA 2BBUA 1SKJA 3OVEA 1R1SA 5EELA 2AOAA 1O4EA 4U17A 3K2MA 2PLDA 2EU0A 2DLYA 2DX0A 4H1OA 2ECDA 1LUMA 4P9VA 1SPSA 1D4WA 3WA4A 3IN7A 1H9OA 3IN8A 2DLZA 1X27A 3VROA 2CIAA 2GE9A 2DM0A 2LQNA 5D0JA 3K2TA 3IMJA 1A1CA 4WWQA 2CI9A 1O49A 4U1PA 1O48A 2CRHA 3PJPA 1BHFA 3QWXX 3VS5A 3EACA 2SRCA 1A1BA 4E68A 2GSBA 2K79B 1O43A 4F5AA 2LNXA 1O4QA 3T04A 4FBNA 3VRNA 2EL8A 5HKYA 1A81A 1AOUF 2IUHA 1FMKA 1F2FA 2IUGA 1BLJA 1LCJA 1SHDA
chains in the Genus database with same CATH topology
4GPLB 1FYRA 2B3OA 2PNAA 3GXWA 1OO4A 3MAZA 1SHAA 4F59A 1O4AA 1FHSA 3ZNIA 5I6VA 3QWYA 2RVFA 1JYUA 1GHUA 4DGXA 3PQZA 1IJRA 1AD5A 1O4CA 1Y1UA 4OHIA 3VRPA 3N8MA 1BHHA 2EYZA 1LUKA 2PTKA 1AB2A 2C9WA 1X6CA 2LQWA 1CSYA 1YVHA 1IS0A 1O46A 1BKLA 1M27A 1KC2A 1R1QA 2MRJA 1CWDL 2IUIA 2PLEA 5AULA 1CSZA 3PSJA 4A4CA 5DC9A 4XZ1A 1PICA 2HDXA 3S8OA 4K45A 3VS1A 3VRZA 3M7FA 3BUWB 1KA7A 1A1EA 1BKMA 2EOBA 3OB1B 2QMSA 2DVJA 2XP1A 4TZIA 1D1ZA 5IBSA 5GJIA 1A1AA 1O4FA 4LUDA 3S9KA 2HCKA 2LNWA 3VRQA 3MXCA 2C0OA 3VS0A 3VS3A 2OQ1A 4XZ0A 1I3ZA 5DC0B 3VS4A 2C0TA 1M61A 3EAZA 1AYAA 1ZFPE 5EHPA 5CDWA 2K7AB 2YSXA 1UURA 2HUWA 1FU6A 1O4HA 4NWGA 3VRRA 1QCFA 1CJ1A 1SHBA 3US4A 1O4LA 2AUGA 2EKXA 1AYBA 2L6KA 1JU5A 1JYQA 2Y1NA 1AYCA 2MQIA 1G83A 4OHDA 4K44A 3GQIB 1O41A 3MXYA 1JWOA 3IMDA 4JE4A 4EIHA 1O4PA 4JGHA 3HIZB 5EHRA 1O4NA 4P9ZA 4OHLA 2YU7A 5HKZA 3UYOA 4FL2A 5AXIA 1O4GA 4A4BA 3CBLA 2AOBA 1RQQC 1O4MA 1QADA 1O4BA 3GXXA 2MC1A 1JYRA 1YVLA 1O42A 3BUOB 5J3XA 2FO0A 2PNBA 3CWGA 1F1WA 3S8NA 3OP0A 2OZOA 2EYVA 1D4TA 4H34A 2L4KA 2KK6A 2L3TA 3PLFB 3BUNB 1BHHB 1LKKA 1AOTF 3PS5A 4OHEA 1K9AA 2Y3AB 2LCTA 3KFJA 1OPLA 1SPRA 3UF4A 1BLKA 1OPKA 4GWFA 2EO6A 1O47A 3VS6A 5EG3B 1RPYA 2H8HA 2SHPA 3CXLA 5KAZA 1TZEE 1A08A 2CR4A 4DGPA 4ROJA 1LCKA 3C7IA 2JYQA 1CWEA 1BG1A 3N84A 1A07A 2H46E 1MILA 4LUEA 1RJAA 3HHMB 3VRYA 2H5KA 4NWFA 3NHNA 1LUIA 2DCRA 4M4ZA 4F5BA 2VIFA 3TL0A 1FBVA 2IZVA 3S8LA 5IBMA 2RMXA 2Y1MA 1GRIA 1NRVA 5DF6A 1AYDA 3BKBA 3PSKA 4K11A 5GJHA 3TKZA 5DC4A 1QG1E 3N7YA 4OHHA 4EY0A 4D8KA 2ETZA 1Z3KA 3VGOA 1O4KA 1FU5A 1O4JA 4L1BB 1KA6A 1FBZA 1OO3A 4GL9E 5HKWA 2CS0A 1WQUA 3VS7A 1O4OA 2ABLA 2CBLA 1BMBA 1O4IA 2HMHA 1NZLA 3VS2A 1KSWA 1X0NA 2EO3A 2C0IA 1O4RA 1HCTB 4K2RA 1NZVA 3BUXB 1MW4A 1A09A 4FL3A 1LKLA 1BFJA 2RORA 1BFIA 1O45A 2MK2A 3PFVA 3OV1A 3BUMB 4QSYA 5BO4A 4JEGA 5EEQA 2CI8A 1Y57A 3CD3A 1XA6A 2MRKA 1HCSB 4X6SA 1LUNA 3HCKA 1BF5A 1O44A 1P13A 1TCEA 1B47A 1O4DA 3OB2B 2FCIA 2EYYA 2RSYA 4E93A 2KNOA 1BM2A 1R1PA 1UUSA 2HDVA 2BBUA 1SKJA 3OVEA 1R1SA 5EELA 2AOAA 1O4EA 4U17A 3K2MA 2PLDA 2EU0A 2DLYA 2DX0A 4H1OA 2ECDA 1LUMA 4P9VA 1SPSA 1D4WA 3WA4A 3IN7A 1H9OA 3IN8A 2DLZA 1X27A 3VROA 2CIAA 2GE9A 2DM0A 2LQNA 5D0JA 3IMJA 1A1CA 4WWQA 2CI9A 1O49A 4U1PA 1O48A 2CRHA 3PJPA 1BHFA 3QWXX 3VS5A 3EACA 2SRCA 1A1BA 4E68A 2GSBA 2K79B 1O43A 4F5AA 2LNXA 1O4QA 3T04A 4FBNA 3VRNA 2EL8A 5HKYA 1A81A 1AOUF 2IUHA 1FMKA 1F2FA 2IUGA 1BLJA 1LCJA 1SHDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GPL B;  1FYR A;  2B3O A;  2PNA A;  3GXW A;  1OO4 A;  3MAZ A;  1SHA A;  4F59 A;  1O4A A;  1FHS A;  3ZNI A;  5I6V A;  3QWY A;  2RVF A;  1JYU A;  1GHU A;  4DGX A;  3PQZ A;  1IJR A;  1AD5 A;  1O4C A;  1Y1U A;  4OHI A;  3VRP A;  3N8M A;  1BHH A;  2EYZ A;  1LUK A;  2PTK A;  1AB2 A;  2C9W A;  1X6C A;  2LQW A;  1CSY A;  1YVH A;  1IS0 A;  1O46 A;  1BKL A;  1M27 A;  1KC2 A;  1R1Q A;  2MRJ A;  1CWD L;  2IUI A;  2PLE A;  5AUL A;  1CSZ A;  3PSJ A;  4A4C A;  5DC9 A;  4XZ1 A;  1PIC A;  2HDX A;  3S8O A;  4K45 A;  3VS1 A;  3VRZ A;  3M7F A;  3BUW B;  1KA7 A;  1A1E A;  1BKM A;  2EOB A;  3OB1 B;  2QMS A;  2DVJ A;  2XP1 A;  4TZI A;  1D1Z A;  5IBS A;  5GJI A;  1A1A A;  1O4F A;  4LUD A;  3S9K A;  2HCK A;  2LNW A;  3VRQ A;  3MXC A;  2C0O A;  3VS0 A;  3VS3 A;  2OQ1 A;  4XZ0 A;  1I3Z A;  5DC0 B;  3VS4 A;  2C0T A;  1M61 A;  3EAZ A;  1AYA A;  1ZFP E;  5EHP A;  5CDW A;  2K7A B;  2YSX A;  1UUR A;  2HUW A;  1FU6 A;  1O4H A;  4NWG A;  3VRR A;  1QCF A;  1CJ1 A;  1SHB A;  3US4 A;  1O4L A;  2AUG A;  2EKX A;  1AYB A;  2L6K A;  1JU5 A;  1JYQ A;  2Y1N A;  1AYC A;  2MQI A;  1G83 A;  4OHD A;  4K44 A;  3GQI B;  1O41 A;  3MXY A;  1JWO A;  3IMD A;  4JE4 A;  4EIH A;  1O4P A;  4JGH A;  3HIZ B;  5EHR A;  1O4N A;  4P9Z A;  4OHL A;  2YU7 A;  5HKZ A;  3UYO A;  4FL2 A;  5AXI A;  1O4G A;  4A4B A;  3CBL A;  2AOB A;  1RQQ C;  1O4M A;  1QAD A;  1O4B A;  3GXX A;  2MC1 A;  1JYR A;  1YVL A;  1O42 A;  3BUO B;  5J3X A;  2FO0 A;  2PNB A;  3CWG A;  1F1W A;  3S8N A;  3OP0 A;  2OZO A;  2EYV A;  1D4T A;  4H34 A;  2L4K A;  2KK6 A;  2L3T A;  3PLF B;  3BUN B;  1BHH B;  1LKK A;  1AOT F;  3PS5 A;  4OHE A;  1K9A A;  2Y3A B;  2LCT A;  3KFJ A;  1OPL A;  1SPR A;  3UF4 A;  1BLK A;  1OPK A;  4GWF A;  2EO6 A;  1O47 A;  3VS6 A;  5EG3 B;  1RPY A;  2H8H A;  2SHP A;  3CXL A;  5KAZ A;  1TZE E;  1A08 A;  2CR4 A;  4DGP A;  4ROJ A;  1LCK A;  3C7I A;  2JYQ A;  1CWE A;  1BG1 A;  3N84 A;  1A07 A;  2H46 E;  1MIL A;  4LUE A;  1RJA A;  3HHM B;  3VRY A;  2H5K A;  4NWF A;  3NHN A;  1LUI A;  2DCR A;  4M4Z A;  4F5B A;  2VIF A;  3TL0 A;  1FBV A;  2IZV A;  3S8L A;  5IBM A;  2RMX A;  2Y1M A;  1GRI A;  1NRV A;  5DF6 A;  1AYD A;  3BKB A;  3PSK A;  4K11 A;  5GJH A;  3TKZ A;  5DC4 A;  1QG1 E;  3N7Y A;  4OHH A;  4EY0 A;  4D8K A;  2ETZ A;  1Z3K A;  3VGO A;  1O4K A;  1FU5 A;  1O4J A;  4L1B B;  1KA6 A;  1FBZ A;  1OO3 A;  4GL9 E;  5HKW A;  2CS0 A;  1WQU A;  3VS7 A;  1O4O A;  2ABL A;  2CBL A;  1BMB A;  1O4I A;  2HMH A;  1NZL A;  3VS2 A;  1KSW A;  1X0N A;  2EO3 A;  2C0I A;  1O4R A;  1HCT B;  4K2R A;  1NZV A;  3BUX B;  1MW4 A;  1A09 A;  4FL3 A;  1LKL A;  1BFJ A;  2ROR A;  1BFI A;  1O45 A;  2MK2 A;  3PFV A;  3OV1 A;  3BUM B;  4QSY A;  5BO4 A;  4JEG A;  5EEQ A;  2CI8 A;  1Y57 A;  3CD3 A;  1XA6 A;  2MRK A;  1HCS B;  4X6S A;  1LUN A;  3HCK A;  1BF5 A;  1O44 A;  1P13 A;  1TCE A;  1B47 A;  1O4D A;  3OB2 B;  2FCI A;  2EYY A;  2RSY A;  4E93 A;  2KNO A;  1BM2 A;  1R1P A;  1UUS A;  2HDV A;  2BBU A;  1SKJ A;  3OVE A;  1R1S A;  5EEL A;  2AOA A;  1O4E A;  4U17 A;  3K2M A;  2PLD A;  2EU0 A;  2DLY A;  2DX0 A;  4H1O A;  2ECD A;  1LUM A;  4P9V A;  1SPS A;  1D4W A;  3WA4 A;  3IN7 A;  1H9O A;  3IN8 A;  2DLZ A;  1X27 A;  3VRO A;  2CIA A;  2GE9 A;  2DM0 A;  2LQN A;  5D0J A;  3IMJ A;  1A1C A;  4WWQ A;  2CI9 A;  1O49 A;  4U1P A;  1O48 A;  2CRH A;  3PJP A;  1BHF A;  3QWX X;  3VS5 A;  3EAC A;  2SRC A;  1A1B A;  4E68 A;  2GSB A;  2K79 B;  1O43 A;  4F5A A;  2LNX A;  1O4Q A;  3T04 A;  4FBN A;  3VRN A;  2EL8 A;  5HKY A;  1A81 A;  1AOU F;  2IUH A;  1FMK A;  1F2F A;  2IUG A;  1BLJ A;  1LCJ A;  1SHD A; 
#chains in the Genus database with same CATH topology
 4GPL B;  1FYR A;  2B3O A;  2PNA A;  3GXW A;  1OO4 A;  3MAZ A;  1SHA A;  4F59 A;  1O4A A;  1FHS A;  3ZNI A;  5I6V A;  3QWY A;  2RVF A;  1JYU A;  1GHU A;  4DGX A;  3PQZ A;  1IJR A;  1AD5 A;  1O4C A;  1Y1U A;  4OHI A;  3VRP A;  3N8M A;  1BHH A;  2EYZ A;  1LUK A;  2PTK A;  1AB2 A;  2C9W A;  1X6C A;  2LQW A;  1CSY A;  1YVH A;  1IS0 A;  1O46 A;  1BKL A;  1M27 A;  1KC2 A;  1R1Q A;  2MRJ A;  1CWD L;  2IUI A;  2PLE A;  5AUL A;  1CSZ A;  3PSJ A;  4A4C A;  5DC9 A;  4XZ1 A;  1PIC A;  2HDX A;  3S8O A;  4K45 A;  3VS1 A;  3VRZ A;  3M7F A;  3BUW B;  1KA7 A;  1A1E A;  1BKM A;  2EOB A;  3OB1 B;  2QMS A;  2DVJ A;  2XP1 A;  4TZI A;  1D1Z A;  5IBS A;  5GJI A;  1A1A A;  1O4F A;  4LUD A;  3S9K A;  2HCK A;  2LNW A;  3VRQ A;  3MXC A;  2C0O A;  3VS0 A;  3VS3 A;  2OQ1 A;  4XZ0 A;  1I3Z A;  5DC0 B;  3VS4 A;  2C0T A;  1M61 A;  3EAZ A;  1AYA A;  1ZFP E;  5EHP A;  5CDW A;  2K7A B;  2YSX A;  1UUR A;  2HUW A;  1FU6 A;  1O4H A;  4NWG A;  3VRR A;  1QCF A;  1CJ1 A;  1SHB A;  3US4 A;  1O4L A;  2AUG A;  2EKX A;  1AYB A;  2L6K A;  1JU5 A;  1JYQ A;  2Y1N A;  1AYC A;  2MQI A;  1G83 A;  4OHD A;  4K44 A;  3GQI B;  1O41 A;  3MXY A;  1JWO A;  3IMD A;  4JE4 A;  4EIH A;  1O4P A;  4JGH A;  3HIZ B;  5EHR A;  1O4N A;  4P9Z A;  4OHL A;  2YU7 A;  5HKZ A;  3UYO A;  4FL2 A;  5AXI A;  1O4G A;  4A4B A;  3CBL A;  2AOB A;  1RQQ C;  1O4M A;  1QAD A;  1O4B A;  3GXX A;  2MC1 A;  1JYR A;  1YVL A;  1O42 A;  3BUO B;  5J3X A;  2FO0 A;  2PNB A;  3CWG A;  1F1W A;  3S8N A;  3OP0 A;  2OZO A;  2EYV A;  1D4T A;  4H34 A;  2L4K A;  2KK6 A;  2L3T A;  3PLF B;  3BUN B;  1BHH B;  1LKK A;  1AOT F;  3PS5 A;  4OHE A;  1K9A A;  2Y3A B;  2LCT A;  3KFJ A;  1OPL A;  1SPR A;  3LYV A;  3UF4 A;  1BLK A;  1OPK A;  4GWF A;  2EO6 A;  1O47 A;  3VS6 A;  5EG3 B;  1RPY A;  2H8H A;  2SHP A;  3CXL A;  5KAZ A;  1TZE E;  1A08 A;  2CR4 A;  4DGP A;  4ROJ A;  1LCK A;  3C7I A;  2JYQ A;  1CWE A;  1BG1 A;  3N84 A;  1A07 A;  2H46 E;  1MIL A;  4LUE A;  1RJA A;  3HHM B;  3VRY A;  2H5K A;  4NWF A;  3NHN A;  1LUI A;  2DCR A;  4M4Z A;  4F5B A;  2VIF A;  3TL0 A;  1FBV A;  2IZV A;  3S8L A;  5IBM A;  2RMX A;  2Y1M A;  1GRI A;  1NRV A;  5DF6 A;  1AYD A;  3BKB A;  3PSK A;  4K11 A;  5GJH A;  3TKZ A;  5DC4 A;  1QG1 E;  3N7Y A;  4OHH A;  4EY0 A;  4D8K A;  2ETZ A;  1Z3K A;  3VGO A;  1O4K A;  1FU5 A;  1O4J A;  4L1B B;  1KA6 A;  1FBZ A;  1OO3 A;  2LRA A;  4GL9 E;  5HKW A;  2CS0 A;  1WQU A;  3VS7 A;  1O4O A;  2ABL A;  2CBL A;  1BMB A;  1O4I A;  2HMH A;  1NZL A;  3VS2 A;  1KSW A;  1X0N A;  2EO3 A;  2C0I A;  1O4R A;  1HCT B;  4K2R A;  1NZV A;  3BUX B;  1MW4 A;  1A09 A;  4FL3 A;  1LKL A;  1BFJ A;  2ROR A;  1BFI A;  1O45 A;  2MK2 A;  3PFV A;  3OV1 A;  3BUM B;  4QSY A;  5BO4 A;  4JEG A;  5EEQ A;  2CI8 A;  1Y57 A;  3CD3 A;  1XA6 A;  2MRK A;  2KGY A;  1HCS B;  4X6S A;  1LUN A;  3HCK A;  1BF5 A;  1O44 A;  1P13 A;  1TCE A;  1B47 A;  1O4D A;  3OB2 B;  2FCI A;  2EYY A;  2RSY A;  4E93 A;  2KNO A;  1BM2 A;  1R1P A;  1UUS A;  2HDV A;  2BBU A;  1SKJ A;  3OVE A;  1R1S A;  5EEL A;  2AOA A;  1O4E A;  4U17 A;  3K2M A;  2PLD A;  2EU0 A;  2DLY A;  2DX0 A;  4H1O A;  2ECD A;  1LUM A;  4P9V A;  1SPS A;  1D4W A;  3WA4 A;  3IN7 A;  1H9O A;  3IN8 A;  2DLZ A;  1X27 A;  3VRO A;  2CIA A;  2GE9 A;  2DM0 A;  2LQN A;  5D0J A;  3K2T A;  3IMJ A;  1A1C A;  4WWQ A;  2CI9 A;  1O49 A;  4U1P A;  1O48 A;  2CRH A;  3PJP A;  1BHF A;  3QWX X;  3VS5 A;  3EAC A;  2SRC A;  1A1B A;  4E68 A;  2GSB A;  2K79 B;  1O43 A;  4F5A A;  2LNX A;  1O4Q A;  3T04 A;  4FBN A;  3VRN A;  2EL8 A;  5HKY A;  1A81 A;  1AOU F;  2IUH A;  1FMK A;  1F2F A;  2IUG A;  1BLJ A;  1LCJ A;  1SHD A; 
#chains in the Genus database with same CATH homology
 4GPL B;  1FYR A;  2B3O A;  2PNA A;  3GXW A;  1OO4 A;  3MAZ A;  1SHA A;  4F59 A;  1O4A A;  1FHS A;  3ZNI A;  5I6V A;  3QWY A;  2RVF A;  1JYU A;  1GHU A;  4DGX A;  3PQZ A;  1IJR A;  1AD5 A;  1O4C A;  1Y1U A;  4OHI A;  3VRP A;  3N8M A;  1BHH A;  2EYZ A;  1LUK A;  2PTK A;  1AB2 A;  2C9W A;  1X6C A;  2LQW A;  1CSY A;  1YVH A;  1IS0 A;  1O46 A;  1BKL A;  1M27 A;  1KC2 A;  1R1Q A;  2MRJ A;  1CWD L;  2IUI A;  2PLE A;  5AUL A;  1CSZ A;  3PSJ A;  4A4C A;  5DC9 A;  4XZ1 A;  1PIC A;  2HDX A;  3S8O A;  4K45 A;  3VS1 A;  3VRZ A;  3M7F A;  3BUW B;  1KA7 A;  1A1E A;  1BKM A;  2EOB A;  3OB1 B;  2QMS A;  2DVJ A;  2XP1 A;  4TZI A;  1D1Z A;  5IBS A;  5GJI A;  1A1A A;  1O4F A;  4LUD A;  3S9K A;  2HCK A;  2LNW A;  3VRQ A;  3MXC A;  2C0O A;  3VS0 A;  3VS3 A;  2OQ1 A;  4XZ0 A;  1I3Z A;  5DC0 B;  3VS4 A;  2C0T A;  1M61 A;  3EAZ A;  1AYA A;  1ZFP E;  5EHP A;  5CDW A;  2K7A B;  2YSX A;  1UUR A;  2HUW A;  1FU6 A;  1O4H A;  4NWG A;  3VRR A;  1QCF A;  1CJ1 A;  1SHB A;  3US4 A;  1O4L A;  2AUG A;  2EKX A;  1AYB A;  2L6K A;  1JU5 A;  1JYQ A;  2Y1N A;  1AYC A;  2MQI A;  1G83 A;  4OHD A;  4K44 A;  3GQI B;  1O41 A;  3MXY A;  1JWO A;  3IMD A;  4JE4 A;  4EIH A;  1O4P A;  4JGH A;  3HIZ B;  5EHR A;  1O4N A;  4P9Z A;  4OHL A;  2YU7 A;  5HKZ A;  3UYO A;  4FL2 A;  5AXI A;  1O4G A;  4A4B A;  3CBL A;  2AOB A;  1RQQ C;  1O4M A;  1QAD A;  1O4B A;  3GXX A;  2MC1 A;  1JYR A;  1YVL A;  1O42 A;  3BUO B;  5J3X A;  2FO0 A;  2PNB A;  3CWG A;  1F1W A;  3S8N A;  3OP0 A;  2OZO A;  2EYV A;  1D4T A;  4H34 A;  2L4K A;  2KK6 A;  2L3T A;  3PLF B;  3BUN B;  1BHH B;  1LKK A;  1AOT F;  3PS5 A;  4OHE A;  1K9A A;  2Y3A B;  2LCT A;  3KFJ A;  1OPL A;  1SPR A;  3UF4 A;  1BLK A;  1OPK A;  4GWF A;  2EO6 A;  1O47 A;  3VS6 A;  5EG3 B;  1RPY A;  2H8H A;  2SHP A;  3CXL A;  5KAZ A;  1TZE E;  1A08 A;  2CR4 A;  4DGP A;  4ROJ A;  1LCK A;  3C7I A;  2JYQ A;  1CWE A;  1BG1 A;  3N84 A;  1A07 A;  2H46 E;  1MIL A;  4LUE A;  1RJA A;  3HHM B;  3VRY A;  2H5K A;  4NWF A;  3NHN A;  1LUI A;  2DCR A;  4M4Z A;  4F5B A;  2VIF A;  3TL0 A;  1FBV A;  2IZV A;  3S8L A;  5IBM A;  2RMX A;  2Y1M A;  1GRI A;  1NRV A;  5DF6 A;  1AYD A;  3BKB A;  3PSK A;  4K11 A;  5GJH A;  3TKZ A;  5DC4 A;  1QG1 E;  3N7Y A;  4OHH A;  4EY0 A;  4D8K A;  2ETZ A;  1Z3K A;  3VGO A;  1O4K A;  1FU5 A;  1O4J A;  4L1B B;  1KA6 A;  1FBZ A;  1OO3 A;  4GL9 E;  5HKW A;  2CS0 A;  1WQU A;  3VS7 A;  1O4O A;  2ABL A;  2CBL A;  1BMB A;  1O4I A;  2HMH A;  1NZL A;  3VS2 A;  1KSW A;  1X0N A;  2EO3 A;  2C0I A;  1O4R A;  1HCT B;  4K2R A;  1NZV A;  3BUX B;  1MW4 A;  1A09 A;  4FL3 A;  1LKL A;  1BFJ A;  2ROR A;  1BFI A;  1O45 A;  2MK2 A;  3PFV A;  3OV1 A;  3BUM B;  4QSY A;  5BO4 A;  4JEG A;  5EEQ A;  2CI8 A;  1Y57 A;  3CD3 A;  1XA6 A;  2MRK A;  1HCS B;  4X6S A;  1LUN A;  3HCK A;  1BF5 A;  1O44 A;  1P13 A;  1TCE A;  1B47 A;  1O4D A;  3OB2 B;  2FCI A;  2EYY A;  2RSY A;  4E93 A;  2KNO A;  1BM2 A;  1R1P A;  1UUS A;  2HDV A;  2BBU A;  1SKJ A;  3OVE A;  1R1S A;  5EEL A;  2AOA A;  1O4E A;  4U17 A;  3K2M A;  2PLD A;  2EU0 A;  2DLY A;  2DX0 A;  4H1O A;  2ECD A;  1LUM A;  4P9V A;  1SPS A;  1D4W A;  3WA4 A;  3IN7 A;  1H9O A;  3IN8 A;  2DLZ A;  1X27 A;  3VRO A;  2CIA A;  2GE9 A;  2DM0 A;  2LQN A;  5D0J A;  3IMJ A;  1A1C A;  4WWQ A;  2CI9 A;  1O49 A;  4U1P A;  1O48 A;  2CRH A;  3PJP A;  1BHF A;  3QWX X;  3VS5 A;  3EAC A;  2SRC A;  1A1B A;  4E68 A;  2GSB A;  2K79 B;  1O43 A;  4F5A A;  2LNX A;  1O4Q A;  3T04 A;  4FBN A;  3VRN A;  2EL8 A;  5HKY A;  1A81 A;  1AOU F;  2IUH A;  1FMK A;  1F2F A;  2IUG A;  1BLJ A;  1LCJ A;  1SHD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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