1O44A

Crystal structure of sh2 in complex with ru85052
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
molecule tags Signaling protein
source organism Homo sapiens
total genus 24
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o44A00
4TZIA 5BO4A 1O4OA 5GJHA 3TKZA 3CWGA 3IN7A 3PFVA 4U1PA 4H1OA 1AD5A 3VS7A 2RMXA 3CXLA 4OHLA 1TCEA 4EIHA 1KC2A 3HHMB 3N8MA 1SHAA 4K11A 4P9ZA 2HUWA 1LCJA 1LCKA 2FO0A 2H5KA 2QMSA 2MQIA 5EELA 1F2FA 4LUDA 1O4DA 1JU5A 1BMBA 4ROJA 2HDXA 4EY0A 1BLJA 1CWDL 1HCTB 3MXYA 3T04A 1FYRA 1FBVA 2AUGA 5AXIA 2VIFA 1JYRA 4D8KA 4GL9E 1D1ZA 1BKMA 1OPLA 2LQWA 3MXCA 5IBSA 1NZVA 2SRCA 1I3ZA 1KA6A 2CRHA 3S8NA 1RQQC 3BUOB 1LUIA 2DLYA 2ETZA 3M7FA 3OB2B 3OVEA 3CBLA 3IN8A 2HMHA 1O47A 2YSXA 1BLKA 1O43A 1B47A 1AYAA 2C9WA 2PNBA 2EKXA 1X6CA 1LUMA 1AB2A 1O45A 5DC9A 5DF6A 2C0OA 1GHUA 1QCFA 2SHPA 1O4IA 4FL3A 1XA6A 4WWQA 1GRIA 1BHFA 3VRPA 1LKLA 3QWYA 1SKJA 4NWGA 2CS0A 2DX0A 5I6VA 2EO6A 3EAZA 1RJAA 1AOUF 1F1WA 3VRZA 1O48A 2C0IA 1H9OA 3GQIB 3PSKA 2H8HA 4GWFA 2L3TA 2PLEA 2RVFA 2YU7A 1TZEE 1SPSA 1A1AA 1MILA 2C0TA 2JYQA 3IMJA 1O49A 1O4QA 3BUNB 4JE4A 4X6SA 2MK2A 1YVHA 4LUEA 1UUSA 3NHNA 1O42A 4P9VA 2IUHA 1A1EA 2IUGA 2DM0A 3GXWA 4FBNA 2DCRA 1O4GA 1A08A 2L6KA 5HKZA 3PS5A 2CI9A 3HIZB 2MC1A 2HCKA 3PQZA 2IUIA 3KFJA 1O4NA 4M4ZA 1AYCA 1M61A 1O4PA 5HKYA 1G83A 1D4TA 4U17A 2K7AB 1X0NA 5EHPA 3VS4A 1OPKA 1SPRA 4E68A 5EEQA 1O4CA 2EL8A 3VROA 2DVJA 3BKBA 1BM2A 1BF5A 4FL2A 1BKLA 4JEGA 4A4BA 2MRJA 3VGOA 1SHDA 1SHBA 1RPYA 2IZVA 1AYBA 1CSYA 3PJPA 5D0JA 2FCIA 3UF4A 1Y57A 2ECDA 2EOBA 2OZOA 5KAZA 1BFIA 1IJRA 2L4KA 2AOAA 1R1SA 1A81A 1R1PA 3S8LA 3GXXA 2EYZA 2LQNA 1JYUA 1O4HA 1JYQA 1O4LA 2OQ1A 1JWOA 1R1QA 1AOTF 2BBUA 3EACA 1MW4A 1O4RA 1UURA 2KK6A 2GSBA 4XZ1A 3S9KA 4QSYA 1HCSB 1FHSA 5CDWA 3BUWB 3CD3A 1O4MA 5EHRA 1D4WA 1FMKA 2B3OA 2DLZA 4K45A 5DC4A 1X27A 1Y1UA 3TL0A 1WQUA 1O44A 1K9AA 1LUNA 4NWFA 4JGHA 2LNWA 3OV1A 3VRQA 1QG1E 4XZ0A 4OHEA 4F5BA 3C7IA 2EO3A 1KA7A 3US4A 3PSJA 2XP1A 3N7YA 4F59A 3PLFB 1ZFPE 4OHIA 2Y3AB 1O4BA 2CIAA 3VS3A 2K79B 1NZLA 2HDVA 1IS0A 3N84A 1QADA 1YVLA 1A07A 5HKWA 1AYDA 4GPLB 1O4EA 3VS0A 1BHHB 2EU0A 4OHHA 1O4KA 5J3XA 4H34A 3UYOA 2PTKA 1LKKA 3WA4A 1A1CA 2PNAA 1BFJA 1O4JA 1O41A 5EG3B 2CI8A 3ZNIA 2LCTA 1KSWA 2MRKA 1M27A 3S8OA 1A1BA 3VS1A 3QWXX 1LUKA 3IMDA 1CJ1A 2KNOA 2LNXA 3VRNA 4DGXA 2EYVA 5IBMA 4DGPA 5AULA 3VS2A 1FBZA 2GE9A 3OP0A 2Y1NA 2AOBA 1NRVA 5DC0B 5GJIA 2ABLA 3VS6A 1CWEA 1BHHA 2H46E 1PICA 1FU6A 1Z3KA 3K2MA 1FU5A 2PLDA 4K44A 1P13A 1A09A 2Y1MA 1CSZA 4K2RA 3VRRA 4A4CA 1BG1A 1O4FA 3HCKA 4F5AA 3VRYA 3OB1B 2CBLA 4L1BB 3BUXB 1O4AA 4OHDA 3VS5A 1OO3A 2RSYA 4E93A 1OO4A 3BUMB 3MAZA 2CR4A 2EYYA 1O46A 2RORA
chains in the Genus database with same CATH superfamily
4TZIA 5BO4A 1O4OA 5GJHA 3TKZA 3CWGA 3IN7A 3PFVA 4U1PA 4H1OA 1AD5A 2KGYA 3VS7A 2RMXA 3CXLA 4OHLA 1TCEA 4EIHA 1KC2A 3HHMB 3N8MA 1SHAA 4K11A 4P9ZA 2HUWA 1LCJA 1LCKA 2FO0A 2H5KA 2QMSA 2MQIA 5EELA 1F2FA 4LUDA 1O4DA 1JU5A 1BMBA 4ROJA 2HDXA 4EY0A 1BLJA 1CWDL 1HCTB 3MXYA 3T04A 1FYRA 1FBVA 2AUGA 5AXIA 2VIFA 1JYRA 4D8KA 4GL9E 1D1ZA 1BKMA 1OPLA 2LQWA 3MXCA 5IBSA 1NZVA 2SRCA 1I3ZA 1KA6A 2CRHA 3S8NA 1RQQC 3BUOB 1LUIA 2DLYA 2ETZA 3M7FA 3OB2B 3OVEA 3CBLA 3IN8A 2HMHA 1O47A 2YSXA 1BLKA 1O43A 1B47A 1AYAA 2C9WA 2PNBA 2EKXA 1X6CA 1LUMA 1AB2A 1O45A 5DC9A 5DF6A 2C0OA 1GHUA 1QCFA 2SHPA 1O4IA 4FL3A 1XA6A 4WWQA 1GRIA 1BHFA 3VRPA 1LKLA 3QWYA 1SKJA 4NWGA 2CS0A 2DX0A 5I6VA 2EO6A 3EAZA 1RJAA 1AOUF 1F1WA 3VRZA 1O48A 2C0IA 1H9OA 3GQIB 3PSKA 2H8HA 4GWFA 2L3TA 2PLEA 2RVFA 2YU7A 1TZEE 1SPSA 1A1AA 1MILA 2C0TA 2JYQA 3IMJA 1O49A 1O4QA 3BUNB 4JE4A 4X6SA 2MK2A 1YVHA 4LUEA 1UUSA 3NHNA 1O42A 4P9VA 2IUHA 1A1EA 2IUGA 2DM0A 3GXWA 4FBNA 2DCRA 1O4GA 1A08A 2L6KA 5HKZA 3PS5A 2CI9A 3HIZB 2MC1A 2HCKA 3PQZA 2IUIA 3KFJA 1O4NA 4M4ZA 1AYCA 1M61A 1O4PA 5HKYA 1G83A 1D4TA 4U17A 2K7AB 1X0NA 5EHPA 3VS4A 1OPKA 1SPRA 4E68A 5EEQA 1O4CA 2EL8A 3VROA 2DVJA 3BKBA 1BM2A 1BF5A 4FL2A 1BKLA 4JEGA 4A4BA 2MRJA 3VGOA 1SHDA 1SHBA 1RPYA 2IZVA 1AYBA 1CSYA 3PJPA 5D0JA 2FCIA 3UF4A 1Y57A 2ECDA 2EOBA 2OZOA 5KAZA 1BFIA 1IJRA 2L4KA 2AOAA 1R1SA 1A81A 1R1PA 3S8LA 3GXXA 2EYZA 2LQNA 1JYUA 1O4HA 1JYQA 1O4LA 2OQ1A 1JWOA 1R1QA 1AOTF 2BBUA 3EACA 1MW4A 1O4RA 1UURA 2KK6A 2GSBA 4XZ1A 3S9KA 4QSYA 1HCSB 1FHSA 5CDWA 3BUWB 3CD3A 1O4MA 5EHRA 1D4WA 1FMKA 2B3OA 2DLZA 4K45A 5DC4A 1X27A 1Y1UA 3TL0A 1WQUA 1O44A 1K9AA 1LUNA 4NWFA 4JGHA 2LNWA 3OV1A 3VRQA 1QG1E 4XZ0A 4OHEA 4F5BA 3C7IA 2EO3A 1KA7A 3US4A 3PSJA 2XP1A 3N7YA 4F59A 3PLFB 1ZFPE 4OHIA 2Y3AB 1O4BA 2CIAA 3VS3A 2K79B 1NZLA 2HDVA 1IS0A 3N84A 1QADA 1YVLA 1A07A 5HKWA 1AYDA 2LRAA 4GPLB 1O4EA 3VS0A 1BHHB 2EU0A 4OHHA 1O4KA 3LYVA 5J3XA 4H34A 3UYOA 2PTKA 1LKKA 3WA4A 1A1CA 2PNAA 1BFJA 1O4JA 1O41A 5EG3B 2CI8A 3ZNIA 2LCTA 1KSWA 2MRKA 1M27A 3S8OA 1A1BA 3VS1A 3QWXX 1LUKA 3IMDA 1CJ1A 2KNOA 2LNXA 3VRNA 4DGXA 2EYVA 5IBMA 4DGPA 5AULA 3VS2A 1FBZA 2GE9A 3OP0A 2Y1NA 2AOBA 1NRVA 5DC0B 5GJIA 2ABLA 3VS6A 1CWEA 1BHHA 2H46E 1PICA 1FU6A 1Z3KA 3K2MA 1FU5A 2PLDA 4K44A 1P13A 1A09A 2Y1MA 1CSZA 4K2RA 3VRRA 4A4CA 1BG1A 1O4FA 3HCKA 4F5AA 3VRYA 3OB1B 2CBLA 4L1BB 3BUXB 1O4AA 4OHDA 3VS5A 1OO3A 2RSYA 4E93A 1OO4A 3BUMB 3MAZA 2CR4A 2EYYA 1O46A 3K2TA 2RORA
chains in the Genus database with same CATH topology
4TZIA 5BO4A 1O4OA 5GJHA 3TKZA 3CWGA 3IN7A 3PFVA 4U1PA 4H1OA 1AD5A 3VS7A 2RMXA 3CXLA 4OHLA 1TCEA 4EIHA 1KC2A 3HHMB 3N8MA 1SHAA 4K11A 4P9ZA 2HUWA 1LCJA 1LCKA 2FO0A 2H5KA 2QMSA 2MQIA 5EELA 1F2FA 4LUDA 1O4DA 1JU5A 1BMBA 4ROJA 2HDXA 4EY0A 1BLJA 1CWDL 1HCTB 3MXYA 3T04A 1FYRA 1FBVA 2AUGA 5AXIA 2VIFA 1JYRA 4D8KA 4GL9E 1D1ZA 1BKMA 1OPLA 2LQWA 3MXCA 5IBSA 1NZVA 2SRCA 1I3ZA 1KA6A 2CRHA 3S8NA 1RQQC 3BUOB 1LUIA 2DLYA 2ETZA 3M7FA 3OB2B 3OVEA 3CBLA 3IN8A 2HMHA 1O47A 2YSXA 1BLKA 1O43A 1B47A 1AYAA 2C9WA 2PNBA 2EKXA 1X6CA 1LUMA 1AB2A 1O45A 5DC9A 5DF6A 2C0OA 1GHUA 1QCFA 2SHPA 1O4IA 4FL3A 1XA6A 4WWQA 1GRIA 1BHFA 3VRPA 1LKLA 3QWYA 1SKJA 4NWGA 2CS0A 2DX0A 5I6VA 2EO6A 3EAZA 1RJAA 1AOUF 1F1WA 3VRZA 1O48A 2C0IA 1H9OA 3GQIB 3PSKA 2H8HA 4GWFA 2L3TA 2PLEA 2RVFA 2YU7A 1TZEE 1SPSA 1A1AA 1MILA 2C0TA 2JYQA 3IMJA 1O49A 1O4QA 3BUNB 4JE4A 4X6SA 2MK2A 1YVHA 4LUEA 1UUSA 3NHNA 1O42A 4P9VA 2IUHA 1A1EA 2IUGA 2DM0A 3GXWA 4FBNA 2DCRA 1O4GA 1A08A 2L6KA 5HKZA 3PS5A 2CI9A 3HIZB 2MC1A 2HCKA 3PQZA 2IUIA 3KFJA 1O4NA 4M4ZA 1AYCA 1M61A 1O4PA 5HKYA 1G83A 1D4TA 4U17A 2K7AB 1X0NA 5EHPA 3VS4A 1OPKA 1SPRA 4E68A 5EEQA 1O4CA 2EL8A 3VROA 2DVJA 3BKBA 1BM2A 1BF5A 4FL2A 1BKLA 4JEGA 4A4BA 2MRJA 3VGOA 1SHDA 1SHBA 1RPYA 2IZVA 1AYBA 1CSYA 3PJPA 5D0JA 2FCIA 3UF4A 1Y57A 2ECDA 2EOBA 2OZOA 5KAZA 1BFIA 1IJRA 2L4KA 2AOAA 1R1SA 1A81A 1R1PA 3S8LA 3GXXA 2EYZA 2LQNA 1JYUA 1O4HA 1JYQA 1O4LA 2OQ1A 1JWOA 1R1QA 1AOTF 2BBUA 3EACA 1MW4A 1O4RA 1UURA 2KK6A 2GSBA 4XZ1A 3S9KA 4QSYA 1HCSB 1FHSA 5CDWA 3BUWB 3CD3A 1O4MA 5EHRA 1D4WA 1FMKA 2B3OA 2DLZA 4K45A 5DC4A 1X27A 1Y1UA 3TL0A 1WQUA 1O44A 1K9AA 1LUNA 4NWFA 4JGHA 2LNWA 3OV1A 3VRQA 1QG1E 4XZ0A 4OHEA 4F5BA 3C7IA 2EO3A 1KA7A 3US4A 3PSJA 2XP1A 3N7YA 4F59A 3PLFB 1ZFPE 4OHIA 2Y3AB 1O4BA 2CIAA 3VS3A 2K79B 1NZLA 2HDVA 1IS0A 3N84A 1QADA 1YVLA 1A07A 5HKWA 1AYDA 4GPLB 1O4EA 3VS0A 1BHHB 2EU0A 4OHHA 1O4KA 5J3XA 4H34A 3UYOA 2PTKA 1LKKA 3WA4A 1A1CA 2PNAA 1BFJA 1O4JA 1O41A 5EG3B 2CI8A 3ZNIA 2LCTA 1KSWA 2MRKA 1M27A 3S8OA 1A1BA 3VS1A 3QWXX 1LUKA 3IMDA 1CJ1A 2KNOA 2LNXA 3VRNA 4DGXA 2EYVA 5IBMA 4DGPA 5AULA 3VS2A 1FBZA 2GE9A 3OP0A 2Y1NA 2AOBA 1NRVA 5DC0B 5GJIA 2ABLA 3VS6A 1CWEA 1BHHA 2H46E 1PICA 1FU6A 1Z3KA 3K2MA 1FU5A 2PLDA 4K44A 1P13A 1A09A 2Y1MA 1CSZA 4K2RA 3VRRA 4A4CA 1BG1A 1O4FA 3HCKA 4F5AA 3VRYA 3OB1B 2CBLA 4L1BB 3BUXB 1O4AA 4OHDA 3VS5A 1OO3A 2RSYA 4E93A 1OO4A 3BUMB 3MAZA 2CR4A 2EYYA 1O46A 2RORA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TZI A;  5BO4 A;  1O4O A;  5GJH A;  3TKZ A;  3CWG A;  3IN7 A;  3PFV A;  4U1P A;  4H1O A;  1AD5 A;  3VS7 A;  2RMX A;  3CXL A;  4OHL A;  1TCE A;  4EIH A;  1KC2 A;  3HHM B;  3N8M A;  1SHA A;  4K11 A;  4P9Z A;  2HUW A;  1LCJ A;  1LCK A;  2FO0 A;  2H5K A;  2QMS A;  2MQI A;  5EEL A;  1F2F A;  4LUD A;  1O4D A;  1JU5 A;  1BMB A;  4ROJ A;  2HDX A;  4EY0 A;  1BLJ A;  1CWD L;  1HCT B;  3MXY A;  3T04 A;  1FYR A;  1FBV A;  2AUG A;  5AXI A;  2VIF A;  1JYR A;  4D8K A;  4GL9 E;  1D1Z A;  1BKM A;  1OPL A;  2LQW A;  3MXC A;  5IBS A;  1NZV A;  2SRC A;  1I3Z A;  1KA6 A;  2CRH A;  3S8N A;  1RQQ C;  3BUO B;  1LUI A;  2DLY A;  2ETZ A;  3M7F A;  3OB2 B;  3OVE A;  3CBL A;  3IN8 A;  2HMH A;  1O47 A;  2YSX A;  1BLK A;  1O43 A;  1B47 A;  1AYA A;  2C9W A;  2PNB A;  2EKX A;  1X6C A;  1LUM A;  1AB2 A;  1O45 A;  5DC9 A;  5DF6 A;  2C0O A;  1GHU A;  1QCF A;  2SHP A;  1O4I A;  4FL3 A;  1XA6 A;  4WWQ A;  1GRI A;  1BHF A;  3VRP A;  1LKL A;  3QWY A;  1SKJ A;  4NWG A;  2CS0 A;  2DX0 A;  5I6V A;  2EO6 A;  3EAZ A;  1RJA A;  1AOU F;  1F1W A;  3VRZ A;  1O48 A;  2C0I A;  1H9O A;  3GQI B;  3PSK A;  2H8H A;  4GWF A;  2L3T A;  2PLE A;  2RVF A;  2YU7 A;  1TZE E;  1SPS A;  1A1A A;  1MIL A;  2C0T A;  2JYQ A;  3IMJ A;  1O49 A;  1O4Q A;  3BUN B;  4JE4 A;  4X6S A;  2MK2 A;  1YVH A;  4LUE A;  1UUS A;  3NHN A;  1O42 A;  4P9V A;  2IUH A;  1A1E A;  2IUG A;  2DM0 A;  3GXW A;  4FBN A;  2DCR A;  1O4G A;  1A08 A;  2L6K A;  5HKZ A;  3PS5 A;  2CI9 A;  3HIZ B;  2MC1 A;  2HCK A;  3PQZ A;  2IUI A;  3KFJ A;  1O4N A;  4M4Z A;  1AYC A;  1M61 A;  1O4P A;  5HKY A;  1G83 A;  1D4T A;  4U17 A;  2K7A B;  1X0N A;  5EHP A;  3VS4 A;  1OPK A;  1SPR A;  4E68 A;  5EEQ A;  1O4C A;  2EL8 A;  3VRO A;  2DVJ A;  3BKB A;  1BM2 A;  1BF5 A;  4FL2 A;  1BKL A;  4JEG A;  4A4B A;  2MRJ A;  3VGO A;  1SHD A;  1SHB A;  1RPY A;  2IZV A;  1AYB A;  1CSY A;  3PJP A;  5D0J A;  2FCI A;  3UF4 A;  1Y57 A;  2ECD A;  2EOB A;  2OZO A;  5KAZ A;  1BFI A;  1IJR A;  2L4K A;  2AOA A;  1R1S A;  1A81 A;  1R1P A;  3S8L A;  3GXX A;  2EYZ A;  2LQN A;  1JYU A;  1O4H A;  1JYQ A;  1O4L A;  2OQ1 A;  1JWO A;  1R1Q A;  1AOT F;  2BBU A;  3EAC A;  1MW4 A;  1O4R A;  1UUR A;  2KK6 A;  2GSB A;  4XZ1 A;  3S9K A;  4QSY A;  1HCS B;  1FHS A;  5CDW A;  3BUW B;  3CD3 A;  1O4M A;  5EHR A;  1D4W A;  1FMK A;  2B3O A;  2DLZ A;  4K45 A;  5DC4 A;  1X27 A;  1Y1U A;  3TL0 A;  1WQU A;  1O44 A;  1K9A A;  1LUN A;  4NWF A;  4JGH A;  2LNW A;  3OV1 A;  3VRQ A;  1QG1 E;  4XZ0 A;  4OHE A;  4F5B A;  3C7I A;  2EO3 A;  1KA7 A;  3US4 A;  3PSJ A;  2XP1 A;  3N7Y A;  4F59 A;  3PLF B;  1ZFP E;  4OHI A;  2Y3A B;  1O4B A;  2CIA A;  3VS3 A;  2K79 B;  1NZL A;  2HDV A;  1IS0 A;  3N84 A;  1QAD A;  1YVL A;  1A07 A;  5HKW A;  1AYD A;  4GPL B;  1O4E A;  3VS0 A;  1BHH B;  2EU0 A;  4OHH A;  1O4K A;  5J3X A;  4H34 A;  3UYO A;  2PTK A;  1LKK A;  3WA4 A;  1A1C A;  2PNA A;  1BFJ A;  1O4J A;  1O41 A;  5EG3 B;  2CI8 A;  3ZNI A;  2LCT A;  1KSW A;  2MRK A;  1M27 A;  3S8O A;  1A1B A;  3VS1 A;  3QWX X;  1LUK A;  3IMD A;  1CJ1 A;  2KNO A;  2LNX A;  3VRN A;  4DGX A;  2EYV A;  5IBM A;  4DGP A;  5AUL A;  3VS2 A;  1FBZ A;  2GE9 A;  3OP0 A;  2Y1N A;  2AOB A;  1NRV A;  5DC0 B;  5GJI A;  2ABL A;  3VS6 A;  1CWE A;  1BHH A;  2H46 E;  1PIC A;  1FU6 A;  1Z3K A;  3K2M A;  1FU5 A;  2PLD A;  4K44 A;  1P13 A;  1A09 A;  2Y1M A;  1CSZ A;  4K2R A;  3VRR A;  4A4C A;  1BG1 A;  1O4F A;  3HCK A;  4F5A A;  3VRY A;  3OB1 B;  2CBL A;  4L1B B;  3BUX B;  1O4A A;  4OHD A;  3VS5 A;  1OO3 A;  2RSY A;  4E93 A;  1OO4 A;  3BUM B;  3MAZ A;  2CR4 A;  2EYY A;  1O46 A;  2ROR A; 
#chains in the Genus database with same CATH topology
 4TZI A;  5BO4 A;  1O4O A;  5GJH A;  3TKZ A;  3CWG A;  3IN7 A;  3PFV A;  4U1P A;  4H1O A;  1AD5 A;  2KGY A;  3VS7 A;  2RMX A;  3CXL A;  4OHL A;  1TCE A;  4EIH A;  1KC2 A;  3HHM B;  3N8M A;  1SHA A;  4K11 A;  4P9Z A;  2HUW A;  1LCJ A;  1LCK A;  2FO0 A;  2H5K A;  2QMS A;  2MQI A;  5EEL A;  1F2F A;  4LUD A;  1O4D A;  1JU5 A;  1BMB A;  4ROJ A;  2HDX A;  4EY0 A;  1BLJ A;  1CWD L;  1HCT B;  3MXY A;  3T04 A;  1FYR A;  1FBV A;  2AUG A;  5AXI A;  2VIF A;  1JYR A;  4D8K A;  4GL9 E;  1D1Z A;  1BKM A;  1OPL A;  2LQW A;  3MXC A;  5IBS A;  1NZV A;  2SRC A;  1I3Z A;  1KA6 A;  2CRH A;  3S8N A;  1RQQ C;  3BUO B;  1LUI A;  2DLY A;  2ETZ A;  3M7F A;  3OB2 B;  3OVE A;  3CBL A;  3IN8 A;  2HMH A;  1O47 A;  2YSX A;  1BLK A;  1O43 A;  1B47 A;  1AYA A;  2C9W A;  2PNB A;  2EKX A;  1X6C A;  1LUM A;  1AB2 A;  1O45 A;  5DC9 A;  5DF6 A;  2C0O A;  1GHU A;  1QCF A;  2SHP A;  1O4I A;  4FL3 A;  1XA6 A;  4WWQ A;  1GRI A;  1BHF A;  3VRP A;  1LKL A;  3QWY A;  1SKJ A;  4NWG A;  2CS0 A;  2DX0 A;  5I6V A;  2EO6 A;  3EAZ A;  1RJA A;  1AOU F;  1F1W A;  3VRZ A;  1O48 A;  2C0I A;  1H9O A;  3GQI B;  3PSK A;  2H8H A;  4GWF A;  2L3T A;  2PLE A;  2RVF A;  2YU7 A;  1TZE E;  1SPS A;  1A1A A;  1MIL A;  2C0T A;  2JYQ A;  3IMJ A;  1O49 A;  1O4Q A;  3BUN B;  4JE4 A;  4X6S A;  2MK2 A;  1YVH A;  4LUE A;  1UUS A;  3NHN A;  1O42 A;  4P9V A;  2IUH A;  1A1E A;  2IUG A;  2DM0 A;  3GXW A;  4FBN A;  2DCR A;  1O4G A;  1A08 A;  2L6K A;  5HKZ A;  3PS5 A;  2CI9 A;  3HIZ B;  2MC1 A;  2HCK A;  3PQZ A;  2IUI A;  3KFJ A;  1O4N A;  4M4Z A;  1AYC A;  1M61 A;  1O4P A;  5HKY A;  1G83 A;  1D4T A;  4U17 A;  2K7A B;  1X0N A;  5EHP A;  3VS4 A;  1OPK A;  1SPR A;  4E68 A;  5EEQ A;  1O4C A;  2EL8 A;  3VRO A;  2DVJ A;  3BKB A;  1BM2 A;  1BF5 A;  4FL2 A;  1BKL A;  4JEG A;  4A4B A;  2MRJ A;  3VGO A;  1SHD A;  1SHB A;  1RPY A;  2IZV A;  1AYB A;  1CSY A;  3PJP A;  5D0J A;  2FCI A;  3UF4 A;  1Y57 A;  2ECD A;  2EOB A;  2OZO A;  5KAZ A;  1BFI A;  1IJR A;  2L4K A;  2AOA A;  1R1S A;  1A81 A;  1R1P A;  3S8L A;  3GXX A;  2EYZ A;  2LQN A;  1JYU A;  1O4H A;  1JYQ A;  1O4L A;  2OQ1 A;  1JWO A;  1R1Q A;  1AOT F;  2BBU A;  3EAC A;  1MW4 A;  1O4R A;  1UUR A;  2KK6 A;  2GSB A;  4XZ1 A;  3S9K A;  4QSY A;  1HCS B;  1FHS A;  5CDW A;  3BUW B;  3CD3 A;  1O4M A;  5EHR A;  1D4W A;  1FMK A;  2B3O A;  2DLZ A;  4K45 A;  5DC4 A;  1X27 A;  1Y1U A;  3TL0 A;  1WQU A;  1O44 A;  1K9A A;  1LUN A;  4NWF A;  4JGH A;  2LNW A;  3OV1 A;  3VRQ A;  1QG1 E;  4XZ0 A;  4OHE A;  4F5B A;  3C7I A;  2EO3 A;  1KA7 A;  3US4 A;  3PSJ A;  2XP1 A;  3N7Y A;  4F59 A;  3PLF B;  1ZFP E;  4OHI A;  2Y3A B;  1O4B A;  2CIA A;  3VS3 A;  2K79 B;  1NZL A;  2HDV A;  1IS0 A;  3N84 A;  1QAD A;  1YVL A;  1A07 A;  5HKW A;  1AYD A;  2LRA A;  4GPL B;  1O4E A;  3VS0 A;  1BHH B;  2EU0 A;  4OHH A;  1O4K A;  3LYV A;  5J3X A;  4H34 A;  3UYO A;  2PTK A;  1LKK A;  3WA4 A;  1A1C A;  2PNA A;  1BFJ A;  1O4J A;  1O41 A;  5EG3 B;  2CI8 A;  3ZNI A;  2LCT A;  1KSW A;  2MRK A;  1M27 A;  3S8O A;  1A1B A;  3VS1 A;  3QWX X;  1LUK A;  3IMD A;  1CJ1 A;  2KNO A;  2LNX A;  3VRN A;  4DGX A;  2EYV A;  5IBM A;  4DGP A;  5AUL A;  3VS2 A;  1FBZ A;  2GE9 A;  3OP0 A;  2Y1N A;  2AOB A;  1NRV A;  5DC0 B;  5GJI A;  2ABL A;  3VS6 A;  1CWE A;  1BHH A;  2H46 E;  1PIC A;  1FU6 A;  1Z3K A;  3K2M A;  1FU5 A;  2PLD A;  4K44 A;  1P13 A;  1A09 A;  2Y1M A;  1CSZ A;  4K2R A;  3VRR A;  4A4C A;  1BG1 A;  1O4F A;  3HCK A;  4F5A A;  3VRY A;  3OB1 B;  2CBL A;  4L1B B;  3BUX B;  1O4A A;  4OHD A;  3VS5 A;  1OO3 A;  2RSY A;  4E93 A;  1OO4 A;  3BUM B;  3MAZ A;  2CR4 A;  2EYY A;  1O46 A;  3K2T A;  2ROR A; 
#chains in the Genus database with same CATH homology
 4TZI A;  5BO4 A;  1O4O A;  5GJH A;  3TKZ A;  3CWG A;  3IN7 A;  3PFV A;  4U1P A;  4H1O A;  1AD5 A;  3VS7 A;  2RMX A;  3CXL A;  4OHL A;  1TCE A;  4EIH A;  1KC2 A;  3HHM B;  3N8M A;  1SHA A;  4K11 A;  4P9Z A;  2HUW A;  1LCJ A;  1LCK A;  2FO0 A;  2H5K A;  2QMS A;  2MQI A;  5EEL A;  1F2F A;  4LUD A;  1O4D A;  1JU5 A;  1BMB A;  4ROJ A;  2HDX A;  4EY0 A;  1BLJ A;  1CWD L;  1HCT B;  3MXY A;  3T04 A;  1FYR A;  1FBV A;  2AUG A;  5AXI A;  2VIF A;  1JYR A;  4D8K A;  4GL9 E;  1D1Z A;  1BKM A;  1OPL A;  2LQW A;  3MXC A;  5IBS A;  1NZV A;  2SRC A;  1I3Z A;  1KA6 A;  2CRH A;  3S8N A;  1RQQ C;  3BUO B;  1LUI A;  2DLY A;  2ETZ A;  3M7F A;  3OB2 B;  3OVE A;  3CBL A;  3IN8 A;  2HMH A;  1O47 A;  2YSX A;  1BLK A;  1O43 A;  1B47 A;  1AYA A;  2C9W A;  2PNB A;  2EKX A;  1X6C A;  1LUM A;  1AB2 A;  1O45 A;  5DC9 A;  5DF6 A;  2C0O A;  1GHU A;  1QCF A;  2SHP A;  1O4I A;  4FL3 A;  1XA6 A;  4WWQ A;  1GRI A;  1BHF A;  3VRP A;  1LKL A;  3QWY A;  1SKJ A;  4NWG A;  2CS0 A;  2DX0 A;  5I6V A;  2EO6 A;  3EAZ A;  1RJA A;  1AOU F;  1F1W A;  3VRZ A;  1O48 A;  2C0I A;  1H9O A;  3GQI B;  3PSK A;  2H8H A;  4GWF A;  2L3T A;  2PLE A;  2RVF A;  2YU7 A;  1TZE E;  1SPS A;  1A1A A;  1MIL A;  2C0T A;  2JYQ A;  3IMJ A;  1O49 A;  1O4Q A;  3BUN B;  4JE4 A;  4X6S A;  2MK2 A;  1YVH A;  4LUE A;  1UUS A;  3NHN A;  1O42 A;  4P9V A;  2IUH A;  1A1E A;  2IUG A;  2DM0 A;  3GXW A;  4FBN A;  2DCR A;  1O4G A;  1A08 A;  2L6K A;  5HKZ A;  3PS5 A;  2CI9 A;  3HIZ B;  2MC1 A;  2HCK A;  3PQZ A;  2IUI A;  3KFJ A;  1O4N A;  4M4Z A;  1AYC A;  1M61 A;  1O4P A;  5HKY A;  1G83 A;  1D4T A;  4U17 A;  2K7A B;  1X0N A;  5EHP A;  3VS4 A;  1OPK A;  1SPR A;  4E68 A;  5EEQ A;  1O4C A;  2EL8 A;  3VRO A;  2DVJ A;  3BKB A;  1BM2 A;  1BF5 A;  4FL2 A;  1BKL A;  4JEG A;  4A4B A;  2MRJ A;  3VGO A;  1SHD A;  1SHB A;  1RPY A;  2IZV A;  1AYB A;  1CSY A;  3PJP A;  5D0J A;  2FCI A;  3UF4 A;  1Y57 A;  2ECD A;  2EOB A;  2OZO A;  5KAZ A;  1BFI A;  1IJR A;  2L4K A;  2AOA A;  1R1S A;  1A81 A;  1R1P A;  3S8L A;  3GXX A;  2EYZ A;  2LQN A;  1JYU A;  1O4H A;  1JYQ A;  1O4L A;  2OQ1 A;  1JWO A;  1R1Q A;  1AOT F;  2BBU A;  3EAC A;  1MW4 A;  1O4R A;  1UUR A;  2KK6 A;  2GSB A;  4XZ1 A;  3S9K A;  4QSY A;  1HCS B;  1FHS A;  5CDW A;  3BUW B;  3CD3 A;  1O4M A;  5EHR A;  1D4W A;  1FMK A;  2B3O A;  2DLZ A;  4K45 A;  5DC4 A;  1X27 A;  1Y1U A;  3TL0 A;  1WQU A;  1O44 A;  1K9A A;  1LUN A;  4NWF A;  4JGH A;  2LNW A;  3OV1 A;  3VRQ A;  1QG1 E;  4XZ0 A;  4OHE A;  4F5B A;  3C7I A;  2EO3 A;  1KA7 A;  3US4 A;  3PSJ A;  2XP1 A;  3N7Y A;  4F59 A;  3PLF B;  1ZFP E;  4OHI A;  2Y3A B;  1O4B A;  2CIA A;  3VS3 A;  2K79 B;  1NZL A;  2HDV A;  1IS0 A;  3N84 A;  1QAD A;  1YVL A;  1A07 A;  5HKW A;  1AYD A;  4GPL B;  1O4E A;  3VS0 A;  1BHH B;  2EU0 A;  4OHH A;  1O4K A;  5J3X A;  4H34 A;  3UYO A;  2PTK A;  1LKK A;  3WA4 A;  1A1C A;  2PNA A;  1BFJ A;  1O4J A;  1O41 A;  5EG3 B;  2CI8 A;  3ZNI A;  2LCT A;  1KSW A;  2MRK A;  1M27 A;  3S8O A;  1A1B A;  3VS1 A;  3QWX X;  1LUK A;  3IMD A;  1CJ1 A;  2KNO A;  2LNX A;  3VRN A;  4DGX A;  2EYV A;  5IBM A;  4DGP A;  5AUL A;  3VS2 A;  1FBZ A;  2GE9 A;  3OP0 A;  2Y1N A;  2AOB A;  1NRV A;  5DC0 B;  5GJI A;  2ABL A;  3VS6 A;  1CWE A;  1BHH A;  2H46 E;  1PIC A;  1FU6 A;  1Z3K A;  3K2M A;  1FU5 A;  2PLD A;  4K44 A;  1P13 A;  1A09 A;  2Y1M A;  1CSZ A;  4K2R A;  3VRR A;  4A4C A;  1BG1 A;  1O4F A;  3HCK A;  4F5A A;  3VRY A;  3OB1 B;  2CBL A;  4L1B B;  3BUX B;  1O4A A;  4OHD A;  3VS5 A;  1OO3 A;  2RSY A;  4E93 A;  1OO4 A;  3BUM B;  3MAZ A;  2CR4 A;  2EYY A;  1O46 A;  2ROR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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