1OO3A

P395s mutant of the p85 regulatory subunit of the n-terminal src homology 2 domain of pi3-kinase
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
111
structure length
111
Chain Sequence
GMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKSIKIFHRDGKYGFSDSLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear magnetic resonance structure of the P395S mutant of the N-SH2 domain of the p85 subunit of PI3 kinase: an SH2 domain with altered specificity
pubmed doi rcsb
molecule tags Protein binding
source organism Bos taurus
molecule keywords Phosphatidylinositol 3-kinase regulatory alpha subunit
total genus 16
structure length 111
sequence length 111
ec nomenclature
pdb deposition date 2003-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1oo3A00
3IN8A 4LUEA 1F2FA 4EY0A 4NWFA 2CRHA 1P13A 1O4LA 1BHFA 1AOUF 1A08A 5DC4A 1F1WA 4EIHA 4FL3A 2HCKA 1BF5A 2EYZA 3N8MA 1SKJA 3VRQA 1G83A 3VGOA 1CSYA 1LCJA 1JYQA 3S9KA 1A1CA 1AYDA 3PQZA 2IUGA 4OHIA 2GE9A 2DVJA 4JE4A 2RVFA 5DF6A 2L3TA 4OHEA 1TCEA 2Y1NA 1O4QA 2MK2A 3WA4A 2Y1MA 3VS5A 4E93A 1OPLA 5KAZA 2DCRA 5GJIA 1X27A 2H5KA 3QWYA 3ZNIA 4L1BB 1AYAA 2YSXA 1O4MA 2C9WA 1O48A 2C0TA 1B47A 2JYQA 4K11A 3M7FA 4K45A 2ECDA 2FCIA 2XP1A 1FBZA 3BUNB 1HCTB 3VRNA 1BHHB 3MAZA 3PFVA 1SHBA 1Z3KA 1O41A 1YVHA 2QMSA 4F5AA 1I3ZA 1O4PA 2EL8A 1A09A 4K44A 3IMJA 1ZFPE 2B3OA 1WQUA 1A1BA 2DLZA 1A81A 2SHPA 2HDXA 2MRJA 5HKWA 2AOAA 1Y57A 2BBUA 4H1OA 2HDVA 1LUMA 1K9AA 1LCKA 1JYRA 2SRCA 1KA6A 3PS5A 1O47A 1O4FA 1FMKA 1LKKA 1OO4A 3IN7A 2EO6A 3OV1A 4WWQA 4P9ZA 3S8OA 2LQWA 3UF4A 3CXLA 3MXYA 5I6VA 1HCSB 1SPRA 4F5BA 1O43A 4ROJA 2RMXA 1AOTF 1QG1E 5IBSA 4GPLB 1O4DA 1X0NA 3S8NA 1NZVA 1M27A 2LQNA 1BKMA 3HCKA 4FBNA 1UURA 1BLJA 2L4KA 1KC2A 2LNXA 1GHUA 3PLFB 1O45A 3PSKA 1O4CA 1BM2A 2HUWA 5HKYA 1NZLA 4JEGA 5EEQA 1M61A 3TL0A 2OZOA 1O4BA 3N84A 1FHSA 2CS0A 1XA6A 2OQ1A 1LUIA 3VS3A 1KA7A 3CD3A 4U17A 3VS4A 4DGXA 1LUNA 1O4NA 1O4JA 4GL9E 1AYCA 5AULA 4OHDA 1OO3A 1SHDA 2H46E 3NHNA 1Y1UA 5HKZA 2K79B 3PSJA 1D4WA 4TZIA 2EOBA 3OB2B 1O4AA 1O4OA 4D8KA 2YU7A 1O4HA 3PJPA 2IZVA 3OB1B 1GRIA 4OHHA 3BKBA 2PLEA 2PNAA 1FU6A 5BO4A 5DC0B 1UUSA 3GXXA 2EO3A 4XZ0A 3VS6A 3IMDA 1BKLA 3HHMB 3BUXB 2IUIA 4M4ZA 2FO0A 1FU5A 3EAZA 1O4GA 1RQQC 2MRKA 2C0OA 1JYUA 1O4RA 1FBVA 1JWOA 3VRPA 1LKLA 5DC9A 5EG3B 2CR4A 1BLKA 1A07A 1AYBA 1OPKA 1QADA 2C0IA 2DLYA 1CSZA 2DX0A 3KFJA 5CDWA 2EYYA 4OHLA 4P9VA 2ETZA 3CBLA 2KNOA 1O4KA 1O49A 2K7AB 2Y3AB 5AXIA 1BG1A 4GWFA 1TZEE 3S8LA 1AB2A 2EU0A 1PICA 4H34A 1YVLA 3BUOB 3US4A 2KK6A 1LUKA 2LCTA 5D0JA 1NRVA 4DGPA 2RORA 5J3XA 5GJHA 1RJAA 2PNBA 1R1PA 1SPSA 2EYVA 3OP0A 3GQIB 1A1EA 1D1ZA 2LNWA 4E68A 1O42A 1D4TA 3K2MA 1O4EA 2PLDA 2MQIA 1IS0A 1R1QA 2MC1A 3VRZA 1AD5A 2EKXA 2PTKA 5EHRA 1BFJA 2HMHA 2H8HA 4K2RA 3VRRA 3BUMB 1O44A 4F59A 2GSBA 3HIZB 4U1PA 4LUDA 1O4IA 3CWGA 2AOBA 5EELA 3VROA 2CIAA 1BFIA 4FL2A 3GXWA 2RSYA 4A4CA 4JGHA 4A4BA 3UYOA 1X6CA 3QWXX 3T04A 3VS2A 1BMBA 3VRYA 1A1AA 3BUWB 1KSWA 3TKZA 3VS7A 4NWGA 3VS0A 1BHHA 3MXCA 5IBMA 2DM0A 4X6SA 2CI9A 3EACA 5EHPA 1RPYA 2VIFA 1H9OA 2L6KA 1MW4A 2CI8A 3OVEA 2CBLA 1CJ1A 3VS1A 1FYRA 2ABLA 1CWDL 4XZ1A 1CWEA 2IUHA 1O46A 1IJRA 1SHAA 3N7YA 1MILA 4QSYA 1R1SA 1JU5A 1QCFA 3C7IA 2AUGA
chains in the Genus database with same CATH superfamily
3IN8A 4LUEA 1F2FA 4EY0A 4NWFA 2CRHA 1P13A 1O4LA 1BHFA 1AOUF 1A08A 5DC4A 1F1WA 4EIHA 4FL3A 2HCKA 1BF5A 2EYZA 3N8MA 1SKJA 3VRQA 1G83A 3VGOA 1CSYA 1LCJA 1JYQA 3S9KA 1A1CA 1AYDA 3PQZA 2IUGA 4OHIA 2GE9A 2DVJA 4JE4A 2RVFA 5DF6A 2L3TA 4OHEA 1TCEA 2Y1NA 1O4QA 2MK2A 3WA4A 2Y1MA 3VS5A 4E93A 1OPLA 5KAZA 2DCRA 5GJIA 1X27A 2H5KA 3QWYA 3ZNIA 4L1BB 1AYAA 2YSXA 1O4MA 2C9WA 1O48A 2C0TA 1B47A 2JYQA 4K11A 3M7FA 4K45A 2ECDA 2FCIA 2XP1A 1FBZA 3BUNB 1HCTB 3VRNA 1BHHB 3MAZA 3PFVA 1SHBA 1Z3KA 2KGYA 1O41A 1YVHA 2QMSA 4F5AA 1I3ZA 1O4PA 2EL8A 1A09A 4K44A 3IMJA 1ZFPE 2B3OA 1WQUA 1A1BA 2DLZA 1A81A 2SHPA 2HDXA 2MRJA 5HKWA 2AOAA 1Y57A 2BBUA 4H1OA 2HDVA 1LUMA 1K9AA 1LCKA 1JYRA 2SRCA 1KA6A 3PS5A 1O47A 1O4FA 1FMKA 1LKKA 1OO4A 3IN7A 2EO6A 3OV1A 4WWQA 4P9ZA 3S8OA 2LQWA 3K2TA 3UF4A 3CXLA 3MXYA 5I6VA 1HCSB 1SPRA 4F5BA 1O43A 4ROJA 2RMXA 1AOTF 1QG1E 5IBSA 4GPLB 1O4DA 1X0NA 3S8NA 1NZVA 1M27A 2LQNA 1BKMA 3HCKA 4FBNA 1UURA 1BLJA 2L4KA 1KC2A 2LNXA 1GHUA 3PLFB 1O45A 3PSKA 1O4CA 1BM2A 2HUWA 5HKYA 1NZLA 4JEGA 5EEQA 1M61A 3TL0A 2OZOA 1O4BA 3N84A 1FHSA 2CS0A 1XA6A 2OQ1A 1LUIA 3VS3A 1KA7A 3CD3A 4U17A 3VS4A 4DGXA 1LUNA 1O4NA 1O4JA 4GL9E 1AYCA 5AULA 4OHDA 1OO3A 1SHDA 2H46E 3NHNA 1Y1UA 5HKZA 2K79B 3PSJA 1D4WA 4TZIA 2EOBA 3OB2B 1O4AA 1O4OA 4D8KA 2YU7A 1O4HA 3PJPA 2IZVA 3OB1B 1GRIA 4OHHA 3BKBA 2PLEA 2PNAA 1FU6A 5BO4A 5DC0B 1UUSA 3GXXA 2EO3A 4XZ0A 3VS6A 3IMDA 1BKLA 3HHMB 3BUXB 2IUIA 4M4ZA 2FO0A 1FU5A 3EAZA 1O4GA 1RQQC 2MRKA 2C0OA 1JYUA 1O4RA 1FBVA 1JWOA 3VRPA 1LKLA 5DC9A 5EG3B 2CR4A 1BLKA 1A07A 1AYBA 1OPKA 1QADA 2C0IA 2DLYA 1CSZA 2DX0A 3KFJA 5CDWA 2EYYA 4OHLA 4P9VA 2ETZA 3CBLA 2KNOA 1O4KA 1O49A 2K7AB 2Y3AB 5AXIA 1BG1A 4GWFA 1TZEE 3S8LA 1AB2A 2EU0A 1PICA 4H34A 1YVLA 3BUOB 3US4A 2KK6A 1LUKA 2LCTA 5D0JA 1NRVA 4DGPA 2RORA 5J3XA 5GJHA 1RJAA 2PNBA 1R1PA 1SPSA 2EYVA 3OP0A 3GQIB 1A1EA 1D1ZA 2LNWA 4E68A 1O42A 1D4TA 3K2MA 1O4EA 2PLDA 2MQIA 1IS0A 1R1QA 2MC1A 3VRZA 1AD5A 2EKXA 2PTKA 5EHRA 1BFJA 2HMHA 2H8HA 4K2RA 3VRRA 3BUMB 1O44A 4F59A 2GSBA 3HIZB 4U1PA 4LUDA 1O4IA 3CWGA 2AOBA 5EELA 3VROA 2CIAA 1BFIA 4FL2A 3GXWA 2RSYA 2LRAA 4A4CA 4JGHA 4A4BA 3UYOA 1X6CA 3QWXX 3T04A 3VS2A 1BMBA 3VRYA 1A1AA 3BUWB 1KSWA 3TKZA 3VS7A 4NWGA 3VS0A 1BHHA 3MXCA 5IBMA 2DM0A 4X6SA 2CI9A 3EACA 5EHPA 1RPYA 2VIFA 1H9OA 2L6KA 1MW4A 2CI8A 3OVEA 2CBLA 1CJ1A 3VS1A 1FYRA 2ABLA 1CWDL 3LYVA 4XZ1A 1CWEA 2IUHA 1O46A 1IJRA 1SHAA 3N7YA 1MILA 4QSYA 1R1SA 1JU5A 1QCFA 3C7IA 2AUGA
chains in the Genus database with same CATH topology
3IN8A 4LUEA 1F2FA 4EY0A 4NWFA 2CRHA 1P13A 1O4LA 1BHFA 1AOUF 1A08A 5DC4A 1F1WA 4EIHA 4FL3A 2HCKA 1BF5A 2EYZA 3N8MA 1SKJA 3VRQA 1G83A 3VGOA 1CSYA 1LCJA 1JYQA 3S9KA 1A1CA 1AYDA 3PQZA 2IUGA 4OHIA 2GE9A 2DVJA 4JE4A 2RVFA 5DF6A 2L3TA 4OHEA 1TCEA 2Y1NA 1O4QA 2MK2A 3WA4A 2Y1MA 3VS5A 4E93A 1OPLA 5KAZA 2DCRA 5GJIA 1X27A 2H5KA 3QWYA 3ZNIA 4L1BB 1AYAA 2YSXA 1O4MA 2C9WA 1O48A 2C0TA 1B47A 2JYQA 4K11A 3M7FA 4K45A 2ECDA 2FCIA 2XP1A 1FBZA 3BUNB 1HCTB 3VRNA 1BHHB 3MAZA 3PFVA 1SHBA 1Z3KA 1O41A 1YVHA 2QMSA 4F5AA 1I3ZA 1O4PA 2EL8A 1A09A 4K44A 3IMJA 1ZFPE 2B3OA 1WQUA 1A1BA 2DLZA 1A81A 2SHPA 2HDXA 2MRJA 5HKWA 2AOAA 1Y57A 2BBUA 4H1OA 2HDVA 1LUMA 1K9AA 1LCKA 1JYRA 2SRCA 1KA6A 3PS5A 1O47A 1O4FA 1FMKA 1LKKA 1OO4A 3IN7A 2EO6A 3OV1A 4WWQA 4P9ZA 3S8OA 2LQWA 3UF4A 3CXLA 3MXYA 5I6VA 1HCSB 1SPRA 4F5BA 1O43A 4ROJA 2RMXA 1AOTF 1QG1E 5IBSA 4GPLB 1O4DA 1X0NA 3S8NA 1NZVA 1M27A 2LQNA 1BKMA 3HCKA 4FBNA 1UURA 1BLJA 2L4KA 1KC2A 2LNXA 1GHUA 3PLFB 1O45A 3PSKA 1O4CA 1BM2A 2HUWA 5HKYA 1NZLA 4JEGA 5EEQA 1M61A 3TL0A 2OZOA 1O4BA 3N84A 1FHSA 2CS0A 1XA6A 2OQ1A 1LUIA 3VS3A 1KA7A 3CD3A 4U17A 3VS4A 4DGXA 1LUNA 1O4NA 1O4JA 4GL9E 1AYCA 5AULA 4OHDA 1OO3A 1SHDA 2H46E 3NHNA 1Y1UA 5HKZA 2K79B 3PSJA 1D4WA 4TZIA 2EOBA 3OB2B 1O4AA 1O4OA 4D8KA 2YU7A 1O4HA 3PJPA 2IZVA 3OB1B 1GRIA 4OHHA 3BKBA 2PLEA 2PNAA 1FU6A 5BO4A 5DC0B 1UUSA 3GXXA 2EO3A 4XZ0A 3VS6A 3IMDA 1BKLA 3HHMB 3BUXB 2IUIA 4M4ZA 2FO0A 1FU5A 3EAZA 1O4GA 1RQQC 2MRKA 2C0OA 1JYUA 1O4RA 1FBVA 1JWOA 3VRPA 1LKLA 5DC9A 5EG3B 2CR4A 1BLKA 1A07A 1AYBA 1OPKA 1QADA 2C0IA 2DLYA 1CSZA 2DX0A 3KFJA 5CDWA 2EYYA 4OHLA 4P9VA 2ETZA 3CBLA 2KNOA 1O4KA 1O49A 2K7AB 2Y3AB 5AXIA 1BG1A 4GWFA 1TZEE 3S8LA 1AB2A 2EU0A 1PICA 4H34A 1YVLA 3BUOB 3US4A 2KK6A 1LUKA 2LCTA 5D0JA 1NRVA 4DGPA 2RORA 5J3XA 5GJHA 1RJAA 2PNBA 1R1PA 1SPSA 2EYVA 3OP0A 3GQIB 1A1EA 1D1ZA 2LNWA 4E68A 1O42A 1D4TA 3K2MA 1O4EA 2PLDA 2MQIA 1IS0A 1R1QA 2MC1A 3VRZA 1AD5A 2EKXA 2PTKA 5EHRA 1BFJA 2HMHA 2H8HA 4K2RA 3VRRA 3BUMB 1O44A 4F59A 2GSBA 3HIZB 4U1PA 4LUDA 1O4IA 3CWGA 2AOBA 5EELA 3VROA 2CIAA 1BFIA 4FL2A 3GXWA 2RSYA 4A4CA 4JGHA 4A4BA 3UYOA 1X6CA 3QWXX 3T04A 3VS2A 1BMBA 3VRYA 1A1AA 3BUWB 1KSWA 3TKZA 3VS7A 4NWGA 3VS0A 1BHHA 3MXCA 5IBMA 2DM0A 4X6SA 2CI9A 3EACA 5EHPA 1RPYA 2VIFA 1H9OA 2L6KA 1MW4A 2CI8A 3OVEA 2CBLA 1CJ1A 3VS1A 1FYRA 2ABLA 1CWDL 4XZ1A 1CWEA 2IUHA 1O46A 1IJRA 1SHAA 3N7YA 1MILA 4QSYA 1R1SA 1JU5A 1QCFA 3C7IA 2AUGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IN8 A;  4LUE A;  1F2F A;  4EY0 A;  4NWF A;  2CRH A;  1P13 A;  1O4L A;  1BHF A;  1AOU F;  1A08 A;  5DC4 A;  1F1W A;  4EIH A;  4FL3 A;  2HCK A;  1BF5 A;  2EYZ A;  3N8M A;  1SKJ A;  3VRQ A;  1G83 A;  3VGO A;  1CSY A;  1LCJ A;  1JYQ A;  3S9K A;  1A1C A;  1AYD A;  3PQZ A;  2IUG A;  4OHI A;  2GE9 A;  2DVJ A;  4JE4 A;  2RVF A;  5DF6 A;  2L3T A;  4OHE A;  1TCE A;  2Y1N A;  1O4Q A;  2MK2 A;  3WA4 A;  2Y1M A;  3VS5 A;  4E93 A;  1OPL A;  5KAZ A;  2DCR A;  5GJI A;  1X27 A;  2H5K A;  3QWY A;  3ZNI A;  4L1B B;  1AYA A;  2YSX A;  1O4M A;  2C9W A;  1O48 A;  2C0T A;  1B47 A;  2JYQ A;  4K11 A;  3M7F A;  4K45 A;  2ECD A;  2FCI A;  2XP1 A;  1FBZ A;  3BUN B;  1HCT B;  3VRN A;  1BHH B;  3MAZ A;  3PFV A;  1SHB A;  1Z3K A;  1O41 A;  1YVH A;  2QMS A;  4F5A A;  1I3Z A;  1O4P A;  2EL8 A;  1A09 A;  4K44 A;  3IMJ A;  1ZFP E;  2B3O A;  1WQU A;  1A1B A;  2DLZ A;  1A81 A;  2SHP A;  2HDX A;  2MRJ A;  5HKW A;  2AOA A;  1Y57 A;  2BBU A;  4H1O A;  2HDV A;  1LUM A;  1K9A A;  1LCK A;  1JYR A;  2SRC A;  1KA6 A;  3PS5 A;  1O47 A;  1O4F A;  1FMK A;  1LKK A;  1OO4 A;  3IN7 A;  2EO6 A;  3OV1 A;  4WWQ A;  4P9Z A;  3S8O A;  2LQW A;  3UF4 A;  3CXL A;  3MXY A;  5I6V A;  1HCS B;  1SPR A;  4F5B A;  1O43 A;  4ROJ A;  2RMX A;  1AOT F;  1QG1 E;  5IBS A;  4GPL B;  1O4D A;  1X0N A;  3S8N A;  1NZV A;  1M27 A;  2LQN A;  1BKM A;  3HCK A;  4FBN A;  1UUR A;  1BLJ A;  2L4K A;  1KC2 A;  2LNX A;  1GHU A;  3PLF B;  1O45 A;  3PSK A;  1O4C A;  1BM2 A;  2HUW A;  5HKY A;  1NZL A;  4JEG A;  5EEQ A;  1M61 A;  3TL0 A;  2OZO A;  1O4B A;  3N84 A;  1FHS A;  2CS0 A;  1XA6 A;  2OQ1 A;  1LUI A;  3VS3 A;  1KA7 A;  3CD3 A;  4U17 A;  3VS4 A;  4DGX A;  1LUN A;  1O4N A;  1O4J A;  4GL9 E;  1AYC A;  5AUL A;  4OHD A;  1OO3 A;  1SHD A;  2H46 E;  3NHN A;  1Y1U A;  5HKZ A;  2K79 B;  3PSJ A;  1D4W A;  4TZI A;  2EOB A;  3OB2 B;  1O4A A;  1O4O A;  4D8K A;  2YU7 A;  1O4H A;  3PJP A;  2IZV A;  3OB1 B;  1GRI A;  4OHH A;  3BKB A;  2PLE A;  2PNA A;  1FU6 A;  5BO4 A;  5DC0 B;  1UUS A;  3GXX A;  2EO3 A;  4XZ0 A;  3VS6 A;  3IMD A;  1BKL A;  3HHM B;  3BUX B;  2IUI A;  4M4Z A;  2FO0 A;  1FU5 A;  3EAZ A;  1O4G A;  1RQQ C;  2MRK A;  2C0O A;  1JYU A;  1O4R A;  1FBV A;  1JWO A;  3VRP A;  1LKL A;  5DC9 A;  5EG3 B;  2CR4 A;  1BLK A;  1A07 A;  1AYB A;  1OPK A;  1QAD A;  2C0I A;  2DLY A;  1CSZ A;  2DX0 A;  3KFJ A;  5CDW A;  2EYY A;  4OHL A;  4P9V A;  2ETZ A;  3CBL A;  2KNO A;  1O4K A;  1O49 A;  2K7A B;  2Y3A B;  5AXI A;  1BG1 A;  4GWF A;  1TZE E;  3S8L A;  1AB2 A;  2EU0 A;  1PIC A;  4H34 A;  1YVL A;  3BUO B;  3US4 A;  2KK6 A;  1LUK A;  2LCT A;  5D0J A;  1NRV A;  4DGP A;  2ROR A;  5J3X A;  5GJH A;  1RJA A;  2PNB A;  1R1P A;  1SPS A;  2EYV A;  3OP0 A;  3GQI B;  1A1E A;  1D1Z A;  2LNW A;  4E68 A;  1O42 A;  1D4T A;  3K2M A;  1O4E A;  2PLD A;  2MQI A;  1IS0 A;  1R1Q A;  2MC1 A;  3VRZ A;  1AD5 A;  2EKX A;  2PTK A;  5EHR A;  1BFJ A;  2HMH A;  2H8H A;  4K2R A;  3VRR A;  3BUM B;  1O44 A;  4F59 A;  2GSB A;  3HIZ B;  4U1P A;  4LUD A;  1O4I A;  3CWG A;  2AOB A;  5EEL A;  3VRO A;  2CIA A;  1BFI A;  4FL2 A;  3GXW A;  2RSY A;  4A4C A;  4JGH A;  4A4B A;  3UYO A;  1X6C A;  3QWX X;  3T04 A;  3VS2 A;  1BMB A;  3VRY A;  1A1A A;  3BUW B;  1KSW A;  3TKZ A;  3VS7 A;  4NWG A;  3VS0 A;  1BHH A;  3MXC A;  5IBM A;  2DM0 A;  4X6S A;  2CI9 A;  3EAC A;  5EHP A;  1RPY A;  2VIF A;  1H9O A;  2L6K A;  1MW4 A;  2CI8 A;  3OVE A;  2CBL A;  1CJ1 A;  3VS1 A;  1FYR A;  2ABL A;  1CWD L;  4XZ1 A;  1CWE A;  2IUH A;  1O46 A;  1IJR A;  1SHA A;  3N7Y A;  1MIL A;  4QSY A;  1R1S A;  1JU5 A;  1QCF A;  3C7I A;  2AUG A; 
#chains in the Genus database with same CATH topology
 3IN8 A;  4LUE A;  1F2F A;  4EY0 A;  4NWF A;  2CRH A;  1P13 A;  1O4L A;  1BHF A;  1AOU F;  1A08 A;  5DC4 A;  1F1W A;  4EIH A;  4FL3 A;  2HCK A;  1BF5 A;  2EYZ A;  3N8M A;  1SKJ A;  3VRQ A;  1G83 A;  3VGO A;  1CSY A;  1LCJ A;  1JYQ A;  3S9K A;  1A1C A;  1AYD A;  3PQZ A;  2IUG A;  4OHI A;  2GE9 A;  2DVJ A;  4JE4 A;  2RVF A;  5DF6 A;  2L3T A;  4OHE A;  1TCE A;  2Y1N A;  1O4Q A;  2MK2 A;  3WA4 A;  2Y1M A;  3VS5 A;  4E93 A;  1OPL A;  5KAZ A;  2DCR A;  5GJI A;  1X27 A;  2H5K A;  3QWY A;  3ZNI A;  4L1B B;  1AYA A;  2YSX A;  1O4M A;  2C9W A;  1O48 A;  2C0T A;  1B47 A;  2JYQ A;  4K11 A;  3M7F A;  4K45 A;  2ECD A;  2FCI A;  2XP1 A;  1FBZ A;  3BUN B;  1HCT B;  3VRN A;  1BHH B;  3MAZ A;  3PFV A;  1SHB A;  1Z3K A;  2KGY A;  1O41 A;  1YVH A;  2QMS A;  4F5A A;  1I3Z A;  1O4P A;  2EL8 A;  1A09 A;  4K44 A;  3IMJ A;  1ZFP E;  2B3O A;  1WQU A;  1A1B A;  2DLZ A;  1A81 A;  2SHP A;  2HDX A;  2MRJ A;  5HKW A;  2AOA A;  1Y57 A;  2BBU A;  4H1O A;  2HDV A;  1LUM A;  1K9A A;  1LCK A;  1JYR A;  2SRC A;  1KA6 A;  3PS5 A;  1O47 A;  1O4F A;  1FMK A;  1LKK A;  1OO4 A;  3IN7 A;  2EO6 A;  3OV1 A;  4WWQ A;  4P9Z A;  3S8O A;  2LQW A;  3K2T A;  3UF4 A;  3CXL A;  3MXY A;  5I6V A;  1HCS B;  1SPR A;  4F5B A;  1O43 A;  4ROJ A;  2RMX A;  1AOT F;  1QG1 E;  5IBS A;  4GPL B;  1O4D A;  1X0N A;  3S8N A;  1NZV A;  1M27 A;  2LQN A;  1BKM A;  3HCK A;  4FBN A;  1UUR A;  1BLJ A;  2L4K A;  1KC2 A;  2LNX A;  1GHU A;  3PLF B;  1O45 A;  3PSK A;  1O4C A;  1BM2 A;  2HUW A;  5HKY A;  1NZL A;  4JEG A;  5EEQ A;  1M61 A;  3TL0 A;  2OZO A;  1O4B A;  3N84 A;  1FHS A;  2CS0 A;  1XA6 A;  2OQ1 A;  1LUI A;  3VS3 A;  1KA7 A;  3CD3 A;  4U17 A;  3VS4 A;  4DGX A;  1LUN A;  1O4N A;  1O4J A;  4GL9 E;  1AYC A;  5AUL A;  4OHD A;  1OO3 A;  1SHD A;  2H46 E;  3NHN A;  1Y1U A;  5HKZ A;  2K79 B;  3PSJ A;  1D4W A;  4TZI A;  2EOB A;  3OB2 B;  1O4A A;  1O4O A;  4D8K A;  2YU7 A;  1O4H A;  3PJP A;  2IZV A;  3OB1 B;  1GRI A;  4OHH A;  3BKB A;  2PLE A;  2PNA A;  1FU6 A;  5BO4 A;  5DC0 B;  1UUS A;  3GXX A;  2EO3 A;  4XZ0 A;  3VS6 A;  3IMD A;  1BKL A;  3HHM B;  3BUX B;  2IUI A;  4M4Z A;  2FO0 A;  1FU5 A;  3EAZ A;  1O4G A;  1RQQ C;  2MRK A;  2C0O A;  1JYU A;  1O4R A;  1FBV A;  1JWO A;  3VRP A;  1LKL A;  5DC9 A;  5EG3 B;  2CR4 A;  1BLK A;  1A07 A;  1AYB A;  1OPK A;  1QAD A;  2C0I A;  2DLY A;  1CSZ A;  2DX0 A;  3KFJ A;  5CDW A;  2EYY A;  4OHL A;  4P9V A;  2ETZ A;  3CBL A;  2KNO A;  1O4K A;  1O49 A;  2K7A B;  2Y3A B;  5AXI A;  1BG1 A;  4GWF A;  1TZE E;  3S8L A;  1AB2 A;  2EU0 A;  1PIC A;  4H34 A;  1YVL A;  3BUO B;  3US4 A;  2KK6 A;  1LUK A;  2LCT A;  5D0J A;  1NRV A;  4DGP A;  2ROR A;  5J3X A;  5GJH A;  1RJA A;  2PNB A;  1R1P A;  1SPS A;  2EYV A;  3OP0 A;  3GQI B;  1A1E A;  1D1Z A;  2LNW A;  4E68 A;  1O42 A;  1D4T A;  3K2M A;  1O4E A;  2PLD A;  2MQI A;  1IS0 A;  1R1Q A;  2MC1 A;  3VRZ A;  1AD5 A;  2EKX A;  2PTK A;  5EHR A;  1BFJ A;  2HMH A;  2H8H A;  4K2R A;  3VRR A;  3BUM B;  1O44 A;  4F59 A;  2GSB A;  3HIZ B;  4U1P A;  4LUD A;  1O4I A;  3CWG A;  2AOB A;  5EEL A;  3VRO A;  2CIA A;  1BFI A;  4FL2 A;  3GXW A;  2RSY A;  2LRA A;  4A4C A;  4JGH A;  4A4B A;  3UYO A;  1X6C A;  3QWX X;  3T04 A;  3VS2 A;  1BMB A;  3VRY A;  1A1A A;  3BUW B;  1KSW A;  3TKZ A;  3VS7 A;  4NWG A;  3VS0 A;  1BHH A;  3MXC A;  5IBM A;  2DM0 A;  4X6S A;  2CI9 A;  3EAC A;  5EHP A;  1RPY A;  2VIF A;  1H9O A;  2L6K A;  1MW4 A;  2CI8 A;  3OVE A;  2CBL A;  1CJ1 A;  3VS1 A;  1FYR A;  2ABL A;  1CWD L;  3LYV A;  4XZ1 A;  1CWE A;  2IUH A;  1O46 A;  1IJR A;  1SHA A;  3N7Y A;  1MIL A;  4QSY A;  1R1S A;  1JU5 A;  1QCF A;  3C7I A;  2AUG A; 
#chains in the Genus database with same CATH homology
 3IN8 A;  4LUE A;  1F2F A;  4EY0 A;  4NWF A;  2CRH A;  1P13 A;  1O4L A;  1BHF A;  1AOU F;  1A08 A;  5DC4 A;  1F1W A;  4EIH A;  4FL3 A;  2HCK A;  1BF5 A;  2EYZ A;  3N8M A;  1SKJ A;  3VRQ A;  1G83 A;  3VGO A;  1CSY A;  1LCJ A;  1JYQ A;  3S9K A;  1A1C A;  1AYD A;  3PQZ A;  2IUG A;  4OHI A;  2GE9 A;  2DVJ A;  4JE4 A;  2RVF A;  5DF6 A;  2L3T A;  4OHE A;  1TCE A;  2Y1N A;  1O4Q A;  2MK2 A;  3WA4 A;  2Y1M A;  3VS5 A;  4E93 A;  1OPL A;  5KAZ A;  2DCR A;  5GJI A;  1X27 A;  2H5K A;  3QWY A;  3ZNI A;  4L1B B;  1AYA A;  2YSX A;  1O4M A;  2C9W A;  1O48 A;  2C0T A;  1B47 A;  2JYQ A;  4K11 A;  3M7F A;  4K45 A;  2ECD A;  2FCI A;  2XP1 A;  1FBZ A;  3BUN B;  1HCT B;  3VRN A;  1BHH B;  3MAZ A;  3PFV A;  1SHB A;  1Z3K A;  1O41 A;  1YVH A;  2QMS A;  4F5A A;  1I3Z A;  1O4P A;  2EL8 A;  1A09 A;  4K44 A;  3IMJ A;  1ZFP E;  2B3O A;  1WQU A;  1A1B A;  2DLZ A;  1A81 A;  2SHP A;  2HDX A;  2MRJ A;  5HKW A;  2AOA A;  1Y57 A;  2BBU A;  4H1O A;  2HDV A;  1LUM A;  1K9A A;  1LCK A;  1JYR A;  2SRC A;  1KA6 A;  3PS5 A;  1O47 A;  1O4F A;  1FMK A;  1LKK A;  1OO4 A;  3IN7 A;  2EO6 A;  3OV1 A;  4WWQ A;  4P9Z A;  3S8O A;  2LQW A;  3UF4 A;  3CXL A;  3MXY A;  5I6V A;  1HCS B;  1SPR A;  4F5B A;  1O43 A;  4ROJ A;  2RMX A;  1AOT F;  1QG1 E;  5IBS A;  4GPL B;  1O4D A;  1X0N A;  3S8N A;  1NZV A;  1M27 A;  2LQN A;  1BKM A;  3HCK A;  4FBN A;  1UUR A;  1BLJ A;  2L4K A;  1KC2 A;  2LNX A;  1GHU A;  3PLF B;  1O45 A;  3PSK A;  1O4C A;  1BM2 A;  2HUW A;  5HKY A;  1NZL A;  4JEG A;  5EEQ A;  1M61 A;  3TL0 A;  2OZO A;  1O4B A;  3N84 A;  1FHS A;  2CS0 A;  1XA6 A;  2OQ1 A;  1LUI A;  3VS3 A;  1KA7 A;  3CD3 A;  4U17 A;  3VS4 A;  4DGX A;  1LUN A;  1O4N A;  1O4J A;  4GL9 E;  1AYC A;  5AUL A;  4OHD A;  1OO3 A;  1SHD A;  2H46 E;  3NHN A;  1Y1U A;  5HKZ A;  2K79 B;  3PSJ A;  1D4W A;  4TZI A;  2EOB A;  3OB2 B;  1O4A A;  1O4O A;  4D8K A;  2YU7 A;  1O4H A;  3PJP A;  2IZV A;  3OB1 B;  1GRI A;  4OHH A;  3BKB A;  2PLE A;  2PNA A;  1FU6 A;  5BO4 A;  5DC0 B;  1UUS A;  3GXX A;  2EO3 A;  4XZ0 A;  3VS6 A;  3IMD A;  1BKL A;  3HHM B;  3BUX B;  2IUI A;  4M4Z A;  2FO0 A;  1FU5 A;  3EAZ A;  1O4G A;  1RQQ C;  2MRK A;  2C0O A;  1JYU A;  1O4R A;  1FBV A;  1JWO A;  3VRP A;  1LKL A;  5DC9 A;  5EG3 B;  2CR4 A;  1BLK A;  1A07 A;  1AYB A;  1OPK A;  1QAD A;  2C0I A;  2DLY A;  1CSZ A;  2DX0 A;  3KFJ A;  5CDW A;  2EYY A;  4OHL A;  4P9V A;  2ETZ A;  3CBL A;  2KNO A;  1O4K A;  1O49 A;  2K7A B;  2Y3A B;  5AXI A;  1BG1 A;  4GWF A;  1TZE E;  3S8L A;  1AB2 A;  2EU0 A;  1PIC A;  4H34 A;  1YVL A;  3BUO B;  3US4 A;  2KK6 A;  1LUK A;  2LCT A;  5D0J A;  1NRV A;  4DGP A;  2ROR A;  5J3X A;  5GJH A;  1RJA A;  2PNB A;  1R1P A;  1SPS A;  2EYV A;  3OP0 A;  3GQI B;  1A1E A;  1D1Z A;  2LNW A;  4E68 A;  1O42 A;  1D4T A;  3K2M A;  1O4E A;  2PLD A;  2MQI A;  1IS0 A;  1R1Q A;  2MC1 A;  3VRZ A;  1AD5 A;  2EKX A;  2PTK A;  5EHR A;  1BFJ A;  2HMH A;  2H8H A;  4K2R A;  3VRR A;  3BUM B;  1O44 A;  4F59 A;  2GSB A;  3HIZ B;  4U1P A;  4LUD A;  1O4I A;  3CWG A;  2AOB A;  5EEL A;  3VRO A;  2CIA A;  1BFI A;  4FL2 A;  3GXW A;  2RSY A;  4A4C A;  4JGH A;  4A4B A;  3UYO A;  1X6C A;  3QWX X;  3T04 A;  3VS2 A;  1BMB A;  3VRY A;  1A1A A;  3BUW B;  1KSW A;  3TKZ A;  3VS7 A;  4NWG A;  3VS0 A;  1BHH A;  3MXC A;  5IBM A;  2DM0 A;  4X6S A;  2CI9 A;  3EAC A;  5EHP A;  1RPY A;  2VIF A;  1H9O A;  2L6K A;  1MW4 A;  2CI8 A;  3OVE A;  2CBL A;  1CJ1 A;  3VS1 A;  1FYR A;  2ABL A;  1CWD L;  4XZ1 A;  1CWE A;  2IUH A;  1O46 A;  1IJR A;  1SHA A;  3N7Y A;  1MIL A;  4QSY A;  1R1S A;  1JU5 A;  1QCF A;  3C7I A;  2AUG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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