1Z3KA

Structural insight into the binding diversity between the tyr-phosphorylated human ephrinbs and nck2 sh2 domain
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
98
structure length
98
Chain Sequence
REWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPIFTSEHGEKLYLVRALQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domain.
pubmed doi rcsb
molecule tags Structural genomics, unknown function
source organism Homo sapiens
molecule keywords Cytoplasmic protein NCK2
total genus 6
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 2005-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1z3kA00
1LCKA 5CDWA 4XZ1A 1WQUA 1R1PA 2H5KA 1AYDA 3PLFB 4GL9E 5DC4A 1AYAA 1D4WA 2LQNA 2RVFA 5IBSA 1AB2A 1X6CA 3VGOA 1JU5A 4JE4A 4WWQA 1GHUA 1O44A 5HKZA 2HDVA 3IN8A 1O4MA 2FCIA 1OO3A 2L4KA 1O4QA 2PNAA 2Y3AB 4P9ZA 4F5AA 1O4DA 4FL3A 3N8MA 5DC0B 3NHNA 3US4A 1SHAA 2L6KA 1UURA 4FL2A 1O42A 1KSWA 1O4HA 1ZFPE 3T04A 2C0OA 2EKXA 4EY0A 3BKBA 1KA6A 3TKZA 1O4EA 1G83A 2AOBA 5EELA 2K7AB 1LUMA 1QG1E 2LNXA 5I6VA 4NWFA 3CBLA 1O4NA 2DLZA 3BUOB 3HIZB 3VS0A 1A1EA 3QWYA 2BBUA 2C0IA 2DLYA 1NZLA 1I3ZA 2MC1A 1RJAA 3VS7A 1CSZA 1BMBA 1O4PA 1IS0A 3GQIB 1QCFA 5DF6A 1BM2A 4NWGA 1O4OA 2EYVA 1O4GA 2ETZA 2CR4A 3HHMB 3OB2B 5J3XA 2LCTA 2CBLA 2MK2A 4GWFA 1AOUF 3CXLA 3VS6A 2DCRA 2PLEA 1FBZA 1O45A 2L3TA 1A81A 1BG1A 2CI8A 3BUWB 2RSYA 2C9WA 3VRQA 4DGPA 1FBVA 3BUNB 1BHHA 2AOAA 1O4AA 5HKWA 1H9OA 4EIHA 1CJ1A 1CSYA 2EOBA 4OHDA 1TZEE 2DX0A 2ABLA 2K79B 3C7IA 4U1PA 2DVJA 4X6SA 3PJPA 1PICA 4GPLB 4L1BB 3VROA 2GE9A 2Y1NA 2EYZA 2EO6A 2Y1MA 5EG3B 1BF5A 1JYQA 1XA6A 3PQZA 3K2MA 3OV1A 4K44A 1R1SA 5GJHA 1O47A 2QMSA 5EEQA 5EHPA 3WA4A 3PSJA 3IN7A 3MXCA 2YSXA 1BLJA 4A4BA 2CI9A 3S8LA 3UYOA 5BO4A 1BFIA 4P9VA 1AOTF 2PNBA 1AYCA 1FMKA 3IMDA 3BUXB 1FU5A 2H46E 1AD5A 1A07A 1KA7A 2OZOA 3VRYA 5IBMA 1IJRA 1LKKA 3KFJA 2RORA 4DGXA 5AXIA 4JGHA 1YVLA 1O4KA 1JYRA 4K45A 1A08A 2HCKA 1OPKA 1O4RA 3VS2A 3EAZA 2OQ1A 1YVHA 3HCKA 1D1ZA 2HDXA 5GJIA 4K2RA 1SHDA 1BKLA 1SPRA 2SRCA 4E93A 1BKMA 2CRHA 2IZVA 1D4TA 5DC9A 1AYBA 1FU6A 1O4BA 1SHBA 3S8OA 4H34A 3GXXA 2HUWA 4LUDA 2VIFA 1HCTB 1NRVA 2RMXA 3ZNIA 1P13A 3VRRA 3VS4A 2C0TA 2EYYA 1O4IA 2ECDA 2KNOA 1SKJA 4K11A 1FHSA 3GXWA 4QSYA 5AULA 4OHLA 4F59A 3IMJA 1Y1UA 3N84A 1B47A 2EO3A 3OB1B 1M61A 1Y57A 4H1OA 3PSKA 1A1BA 1HCSB 3EACA 1O4CA 1O4FA 1R1QA 1MILA 4U17A 1BLKA 3VS1A 4OHEA 4D8KA 1QADA 2MRKA 1NZVA 3M7FA 2HMHA 1JWOA 3VS5A 4LUEA 2SHPA 1TCEA 3N7YA 2JYQA 2IUIA 1GRIA 3TL0A 3BUMB 2GSBA 3UF4A 3CWGA 1A1CA 5HKYA 1BHFA 1M27A 2AUGA 1BFJA 4F5BA 2DM0A 3S9KA 1O4JA 2EU0A 2B3OA 1LUIA 4XZ0A 2IUHA 1O43A 3VRPA 1KC2A 1OPLA 2MQIA 3CD3A 3QWXX 1F2FA 1O41A 1O48A 2XP1A 2CIAA 5KAZA 1CWDL 2PLDA 4ROJA 1A1AA 4A4CA 5D0JA 1Z3KA 2MRJA 1LKLA 4FBNA 4OHIA 2LNWA 1A09A 1LUNA 2H8HA 4JEGA 1LCJA 2IUGA 1JYUA 1O4LA 4M4ZA 1X27A 1K9AA 2EL8A 1LUKA 1O49A 1UUSA 3MAZA 1OO4A 1RQQC 3OVEA 4OHHA 1CWEA 1RPYA 2KK6A 1X0NA 1F1WA 2PTKA 3MXYA 3VRZA 4E68A 1O46A 3PS5A 3OP0A 2FO0A 3VS3A 3PFVA 2CS0A 1SPSA 3S8NA 2YU7A 4TZIA 1FYRA 3VRNA 2LQWA 5EHRA 1MW4A 1BHHB
chains in the Genus database with same CATH superfamily
1LCKA 5CDWA 4XZ1A 1WQUA 1R1PA 2H5KA 1AYDA 3PLFB 4GL9E 5DC4A 1AYAA 1D4WA 2LQNA 2RVFA 5IBSA 1AB2A 1X6CA 3VGOA 1JU5A 4JE4A 4WWQA 1GHUA 1O44A 5HKZA 3K2TA 2HDVA 3IN8A 1O4MA 2FCIA 1OO3A 2L4KA 1O4QA 2PNAA 2Y3AB 4P9ZA 4F5AA 1O4DA 4FL3A 3N8MA 5DC0B 3NHNA 3US4A 1SHAA 2L6KA 1UURA 4FL2A 1O42A 1KSWA 1O4HA 1ZFPE 3T04A 2C0OA 2EKXA 4EY0A 3BKBA 1KA6A 3TKZA 1O4EA 1G83A 2AOBA 5EELA 2K7AB 1LUMA 1QG1E 2LNXA 5I6VA 4NWFA 3CBLA 1O4NA 2DLZA 3BUOB 3HIZB 3VS0A 1A1EA 3QWYA 2BBUA 2C0IA 2DLYA 1NZLA 1I3ZA 2MC1A 1RJAA 3VS7A 1CSZA 1BMBA 1O4PA 1IS0A 3GQIB 1QCFA 5DF6A 1BM2A 4NWGA 1O4OA 2EYVA 1O4GA 2ETZA 2CR4A 3HHMB 3OB2B 5J3XA 2LCTA 2CBLA 2MK2A 4GWFA 1AOUF 3CXLA 3VS6A 2DCRA 2PLEA 1FBZA 1O45A 2L3TA 1A81A 1BG1A 2CI8A 3BUWB 2RSYA 2C9WA 3VRQA 4DGPA 1FBVA 3BUNB 1BHHA 2AOAA 1O4AA 5HKWA 1H9OA 4EIHA 1CJ1A 1CSYA 2EOBA 4OHDA 1TZEE 2DX0A 2ABLA 2K79B 3C7IA 3LYVA 4U1PA 2DVJA 2KGYA 4X6SA 3PJPA 1PICA 4GPLB 4L1BB 3VROA 2GE9A 2Y1NA 2EYZA 2EO6A 2Y1MA 5EG3B 1BF5A 1JYQA 1XA6A 3PQZA 3K2MA 3OV1A 4K44A 1R1SA 5GJHA 1O47A 2QMSA 5EEQA 5EHPA 3WA4A 3PSJA 3IN7A 3MXCA 2YSXA 1BLJA 4A4BA 2CI9A 3S8LA 3UYOA 5BO4A 1BFIA 4P9VA 1AOTF 2PNBA 1AYCA 1FMKA 3IMDA 3BUXB 1FU5A 2H46E 1AD5A 1A07A 1KA7A 2OZOA 3VRYA 5IBMA 1IJRA 1LKKA 3KFJA 2RORA 4DGXA 5AXIA 4JGHA 1YVLA 1O4KA 1JYRA 4K45A 1A08A 2HCKA 1OPKA 1O4RA 3VS2A 3EAZA 2OQ1A 1YVHA 3HCKA 1D1ZA 2HDXA 5GJIA 4K2RA 1SHDA 1BKLA 1SPRA 2SRCA 4E93A 1BKMA 2CRHA 2IZVA 1D4TA 5DC9A 1AYBA 1FU6A 1O4BA 1SHBA 3S8OA 4H34A 3GXXA 2HUWA 4LUDA 2VIFA 1HCTB 1NRVA 2RMXA 3ZNIA 1P13A 3VRRA 3VS4A 2C0TA 2EYYA 1O4IA 2ECDA 2KNOA 1SKJA 4K11A 1FHSA 3GXWA 4QSYA 5AULA 4OHLA 4F59A 3IMJA 1Y1UA 3N84A 1B47A 2EO3A 3OB1B 1M61A 1Y57A 4H1OA 3PSKA 1A1BA 1HCSB 3EACA 1O4CA 1O4FA 1R1QA 1MILA 4U17A 1BLKA 2LRAA 3VS1A 4OHEA 4D8KA 1QADA 2MRKA 1NZVA 3M7FA 2HMHA 1JWOA 3VS5A 4LUEA 2SHPA 1TCEA 3N7YA 2JYQA 2IUIA 1GRIA 3TL0A 3BUMB 2GSBA 3UF4A 3CWGA 1A1CA 5HKYA 1BHFA 1M27A 2AUGA 1BFJA 4F5BA 2DM0A 3S9KA 1O4JA 2EU0A 2B3OA 1LUIA 4XZ0A 2IUHA 1O43A 3VRPA 1KC2A 1OPLA 2MQIA 3CD3A 3QWXX 1F2FA 1O41A 1O48A 2XP1A 2CIAA 5KAZA 1CWDL 2PLDA 4ROJA 1A1AA 4A4CA 5D0JA 1Z3KA 2MRJA 1LKLA 4FBNA 4OHIA 2LNWA 1A09A 1LUNA 2H8HA 4JEGA 1LCJA 2IUGA 1JYUA 1O4LA 4M4ZA 1X27A 1K9AA 2EL8A 1LUKA 1O49A 1UUSA 3MAZA 1OO4A 1RQQC 3OVEA 4OHHA 1CWEA 1RPYA 2KK6A 1X0NA 1F1WA 2PTKA 3MXYA 3VRZA 4E68A 1O46A 3PS5A 3OP0A 2FO0A 3VS3A 3PFVA 2CS0A 1SPSA 3S8NA 2YU7A 4TZIA 1FYRA 3VRNA 2LQWA 5EHRA 1MW4A 1BHHB
chains in the Genus database with same CATH topology
1LCKA 5CDWA 4XZ1A 1WQUA 1R1PA 2H5KA 1AYDA 3PLFB 4GL9E 5DC4A 1AYAA 1D4WA 2LQNA 2RVFA 5IBSA 1AB2A 1X6CA 3VGOA 1JU5A 4JE4A 4WWQA 1GHUA 1O44A 5HKZA 2HDVA 3IN8A 1O4MA 2FCIA 1OO3A 2L4KA 1O4QA 2PNAA 2Y3AB 4P9ZA 4F5AA 1O4DA 4FL3A 3N8MA 5DC0B 3NHNA 3US4A 1SHAA 2L6KA 1UURA 4FL2A 1O42A 1KSWA 1O4HA 1ZFPE 3T04A 2C0OA 2EKXA 4EY0A 3BKBA 1KA6A 3TKZA 1O4EA 1G83A 2AOBA 5EELA 2K7AB 1LUMA 1QG1E 2LNXA 5I6VA 4NWFA 3CBLA 1O4NA 2DLZA 3BUOB 3HIZB 3VS0A 1A1EA 3QWYA 2BBUA 2C0IA 2DLYA 1NZLA 1I3ZA 2MC1A 1RJAA 3VS7A 1CSZA 1BMBA 1O4PA 1IS0A 3GQIB 1QCFA 5DF6A 1BM2A 4NWGA 1O4OA 2EYVA 1O4GA 2ETZA 2CR4A 3HHMB 3OB2B 5J3XA 2LCTA 2CBLA 2MK2A 4GWFA 1AOUF 3CXLA 3VS6A 2DCRA 2PLEA 1FBZA 1O45A 2L3TA 1A81A 1BG1A 2CI8A 3BUWB 2RSYA 2C9WA 3VRQA 4DGPA 1FBVA 3BUNB 1BHHA 2AOAA 1O4AA 5HKWA 1H9OA 4EIHA 1CJ1A 1CSYA 2EOBA 4OHDA 1TZEE 2DX0A 2ABLA 2K79B 3C7IA 4U1PA 2DVJA 4X6SA 3PJPA 1PICA 4GPLB 4L1BB 3VROA 2GE9A 2Y1NA 2EYZA 2EO6A 2Y1MA 5EG3B 1BF5A 1JYQA 1XA6A 3PQZA 3K2MA 3OV1A 4K44A 1R1SA 5GJHA 1O47A 2QMSA 5EEQA 5EHPA 3WA4A 3PSJA 3IN7A 3MXCA 2YSXA 1BLJA 4A4BA 2CI9A 3S8LA 3UYOA 5BO4A 1BFIA 4P9VA 1AOTF 2PNBA 1AYCA 1FMKA 3IMDA 3BUXB 1FU5A 2H46E 1AD5A 1A07A 1KA7A 2OZOA 3VRYA 5IBMA 1IJRA 1LKKA 3KFJA 2RORA 4DGXA 5AXIA 4JGHA 1YVLA 1O4KA 1JYRA 4K45A 1A08A 2HCKA 1OPKA 1O4RA 3VS2A 3EAZA 2OQ1A 1YVHA 3HCKA 1D1ZA 2HDXA 5GJIA 4K2RA 1SHDA 1BKLA 1SPRA 2SRCA 4E93A 1BKMA 2CRHA 2IZVA 1D4TA 5DC9A 1AYBA 1FU6A 1O4BA 1SHBA 3S8OA 4H34A 3GXXA 2HUWA 4LUDA 2VIFA 1HCTB 1NRVA 2RMXA 3ZNIA 1P13A 3VRRA 3VS4A 2C0TA 2EYYA 1O4IA 2ECDA 2KNOA 1SKJA 4K11A 1FHSA 3GXWA 4QSYA 5AULA 4OHLA 4F59A 3IMJA 1Y1UA 3N84A 1B47A 2EO3A 3OB1B 1M61A 1Y57A 4H1OA 3PSKA 1A1BA 1HCSB 3EACA 1O4CA 1O4FA 1R1QA 1MILA 4U17A 1BLKA 3VS1A 4OHEA 4D8KA 1QADA 2MRKA 1NZVA 3M7FA 2HMHA 1JWOA 3VS5A 4LUEA 2SHPA 1TCEA 3N7YA 2JYQA 2IUIA 1GRIA 3TL0A 3BUMB 2GSBA 3UF4A 3CWGA 1A1CA 5HKYA 1BHFA 1M27A 2AUGA 1BFJA 4F5BA 2DM0A 3S9KA 1O4JA 2EU0A 2B3OA 1LUIA 4XZ0A 2IUHA 1O43A 3VRPA 1KC2A 1OPLA 2MQIA 3CD3A 3QWXX 1F2FA 1O41A 1O48A 2XP1A 2CIAA 5KAZA 1CWDL 2PLDA 4ROJA 1A1AA 4A4CA 5D0JA 1Z3KA 2MRJA 1LKLA 4FBNA 4OHIA 2LNWA 1A09A 1LUNA 2H8HA 4JEGA 1LCJA 2IUGA 1JYUA 1O4LA 4M4ZA 1X27A 1K9AA 2EL8A 1LUKA 1O49A 1UUSA 3MAZA 1OO4A 1RQQC 3OVEA 4OHHA 1CWEA 1RPYA 2KK6A 1X0NA 1F1WA 2PTKA 3MXYA 3VRZA 4E68A 1O46A 3PS5A 3OP0A 2FO0A 3VS3A 3PFVA 2CS0A 1SPSA 3S8NA 2YU7A 4TZIA 1FYRA 3VRNA 2LQWA 5EHRA 1MW4A 1BHHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LCK A;  5CDW A;  4XZ1 A;  1WQU A;  1R1P A;  2H5K A;  1AYD A;  3PLF B;  4GL9 E;  5DC4 A;  1AYA A;  1D4W A;  2LQN A;  2RVF A;  5IBS A;  1AB2 A;  1X6C A;  3VGO A;  1JU5 A;  4JE4 A;  4WWQ A;  1GHU A;  1O44 A;  5HKZ A;  2HDV A;  3IN8 A;  1O4M A;  2FCI A;  1OO3 A;  2L4K A;  1O4Q A;  2PNA A;  2Y3A B;  4P9Z A;  4F5A A;  1O4D A;  4FL3 A;  3N8M A;  5DC0 B;  3NHN A;  3US4 A;  1SHA A;  2L6K A;  1UUR A;  4FL2 A;  1O42 A;  1KSW A;  1O4H A;  1ZFP E;  3T04 A;  2C0O A;  2EKX A;  4EY0 A;  3BKB A;  1KA6 A;  3TKZ A;  1O4E A;  1G83 A;  2AOB A;  5EEL A;  2K7A B;  1LUM A;  1QG1 E;  2LNX A;  5I6V A;  4NWF A;  3CBL A;  1O4N A;  2DLZ A;  3BUO B;  3HIZ B;  3VS0 A;  1A1E A;  3QWY A;  2BBU A;  2C0I A;  2DLY A;  1NZL A;  1I3Z A;  2MC1 A;  1RJA A;  3VS7 A;  1CSZ A;  1BMB A;  1O4P A;  1IS0 A;  3GQI B;  1QCF A;  5DF6 A;  1BM2 A;  4NWG A;  1O4O A;  2EYV A;  1O4G A;  2ETZ A;  2CR4 A;  3HHM B;  3OB2 B;  5J3X A;  2LCT A;  2CBL A;  2MK2 A;  4GWF A;  1AOU F;  3CXL A;  3VS6 A;  2DCR A;  2PLE A;  1FBZ A;  1O45 A;  2L3T A;  1A81 A;  1BG1 A;  2CI8 A;  3BUW B;  2RSY A;  2C9W A;  3VRQ A;  4DGP A;  1FBV A;  3BUN B;  1BHH A;  2AOA A;  1O4A A;  5HKW A;  1H9O A;  4EIH A;  1CJ1 A;  1CSY A;  2EOB A;  4OHD A;  1TZE E;  2DX0 A;  2ABL A;  2K79 B;  3C7I A;  4U1P A;  2DVJ A;  4X6S A;  3PJP A;  1PIC A;  4GPL B;  4L1B B;  3VRO A;  2GE9 A;  2Y1N A;  2EYZ A;  2EO6 A;  2Y1M A;  5EG3 B;  1BF5 A;  1JYQ A;  1XA6 A;  3PQZ A;  3K2M A;  3OV1 A;  4K44 A;  1R1S A;  5GJH A;  1O47 A;  2QMS A;  5EEQ A;  5EHP A;  3WA4 A;  3PSJ A;  3IN7 A;  3MXC A;  2YSX A;  1BLJ A;  4A4B A;  2CI9 A;  3S8L A;  3UYO A;  5BO4 A;  1BFI A;  4P9V A;  1AOT F;  2PNB A;  1AYC A;  1FMK A;  3IMD A;  3BUX B;  1FU5 A;  2H46 E;  1AD5 A;  1A07 A;  1KA7 A;  2OZO A;  3VRY A;  5IBM A;  1IJR A;  1LKK A;  3KFJ A;  2ROR A;  4DGX A;  5AXI A;  4JGH A;  1YVL A;  1O4K A;  1JYR A;  4K45 A;  1A08 A;  2HCK A;  1OPK A;  1O4R A;  3VS2 A;  3EAZ A;  2OQ1 A;  1YVH A;  3HCK A;  1D1Z A;  2HDX A;  5GJI A;  4K2R A;  1SHD A;  1BKL A;  1SPR A;  2SRC A;  4E93 A;  1BKM A;  2CRH A;  2IZV A;  1D4T A;  5DC9 A;  1AYB A;  1FU6 A;  1O4B A;  1SHB A;  3S8O A;  4H34 A;  3GXX A;  2HUW A;  4LUD A;  2VIF A;  1HCT B;  1NRV A;  2RMX A;  3ZNI A;  1P13 A;  3VRR A;  3VS4 A;  2C0T A;  2EYY A;  1O4I A;  2ECD A;  2KNO A;  1SKJ A;  4K11 A;  1FHS A;  3GXW A;  4QSY A;  5AUL A;  4OHL A;  4F59 A;  3IMJ A;  1Y1U A;  3N84 A;  1B47 A;  2EO3 A;  3OB1 B;  1M61 A;  1Y57 A;  4H1O A;  3PSK A;  1A1B A;  1HCS B;  3EAC A;  1O4C A;  1O4F A;  1R1Q A;  1MIL A;  4U17 A;  1BLK A;  3VS1 A;  4OHE A;  4D8K A;  1QAD A;  2MRK A;  1NZV A;  3M7F A;  2HMH A;  1JWO A;  3VS5 A;  4LUE A;  2SHP A;  1TCE A;  3N7Y A;  2JYQ A;  2IUI A;  1GRI A;  3TL0 A;  3BUM B;  2GSB A;  3UF4 A;  3CWG A;  1A1C A;  5HKY A;  1BHF A;  1M27 A;  2AUG A;  1BFJ A;  4F5B A;  2DM0 A;  3S9K A;  1O4J A;  2EU0 A;  2B3O A;  1LUI A;  4XZ0 A;  2IUH A;  1O43 A;  3VRP A;  1KC2 A;  1OPL A;  2MQI A;  3CD3 A;  3QWX X;  1F2F A;  1O41 A;  1O48 A;  2XP1 A;  2CIA A;  5KAZ A;  1CWD L;  2PLD A;  4ROJ A;  1A1A A;  4A4C A;  5D0J A;  1Z3K A;  2MRJ A;  1LKL A;  4FBN A;  4OHI A;  2LNW A;  1A09 A;  1LUN A;  2H8H A;  4JEG A;  1LCJ A;  2IUG A;  1JYU A;  1O4L A;  4M4Z A;  1X27 A;  1K9A A;  2EL8 A;  1LUK A;  1O49 A;  1UUS A;  3MAZ A;  1OO4 A;  1RQQ C;  3OVE A;  4OHH A;  1CWE A;  1RPY A;  2KK6 A;  1X0N A;  1F1W A;  2PTK A;  3MXY A;  3VRZ A;  4E68 A;  1O46 A;  3PS5 A;  3OP0 A;  2FO0 A;  3VS3 A;  3PFV A;  2CS0 A;  1SPS A;  3S8N A;  2YU7 A;  4TZI A;  1FYR A;  3VRN A;  2LQW A;  5EHR A;  1MW4 A;  1BHH B; 
#chains in the Genus database with same CATH topology
 1LCK A;  5CDW A;  4XZ1 A;  1WQU A;  1R1P A;  2H5K A;  1AYD A;  3PLF B;  4GL9 E;  5DC4 A;  1AYA A;  1D4W A;  2LQN A;  2RVF A;  5IBS A;  1AB2 A;  1X6C A;  3VGO A;  1JU5 A;  4JE4 A;  4WWQ A;  1GHU A;  1O44 A;  5HKZ A;  3K2T A;  2HDV A;  3IN8 A;  1O4M A;  2FCI A;  1OO3 A;  2L4K A;  1O4Q A;  2PNA A;  2Y3A B;  4P9Z A;  4F5A A;  1O4D A;  4FL3 A;  3N8M A;  5DC0 B;  3NHN A;  3US4 A;  1SHA A;  2L6K A;  1UUR A;  4FL2 A;  1O42 A;  1KSW A;  1O4H A;  1ZFP E;  3T04 A;  2C0O A;  2EKX A;  4EY0 A;  3BKB A;  1KA6 A;  3TKZ A;  1O4E A;  1G83 A;  2AOB A;  5EEL A;  2K7A B;  1LUM A;  1QG1 E;  2LNX A;  5I6V A;  4NWF A;  3CBL A;  1O4N A;  2DLZ A;  3BUO B;  3HIZ B;  3VS0 A;  1A1E A;  3QWY A;  2BBU A;  2C0I A;  2DLY A;  1NZL A;  1I3Z A;  2MC1 A;  1RJA A;  3VS7 A;  1CSZ A;  1BMB A;  1O4P A;  1IS0 A;  3GQI B;  1QCF A;  5DF6 A;  1BM2 A;  4NWG A;  1O4O A;  2EYV A;  1O4G A;  2ETZ A;  2CR4 A;  3HHM B;  3OB2 B;  5J3X A;  2LCT A;  2CBL A;  2MK2 A;  4GWF A;  1AOU F;  3CXL A;  3VS6 A;  2DCR A;  2PLE A;  1FBZ A;  1O45 A;  2L3T A;  1A81 A;  1BG1 A;  2CI8 A;  3BUW B;  2RSY A;  2C9W A;  3VRQ A;  4DGP A;  1FBV A;  3BUN B;  1BHH A;  2AOA A;  1O4A A;  5HKW A;  1H9O A;  4EIH A;  1CJ1 A;  1CSY A;  2EOB A;  4OHD A;  1TZE E;  2DX0 A;  2ABL A;  2K79 B;  3C7I A;  3LYV A;  4U1P A;  2DVJ A;  2KGY A;  4X6S A;  3PJP A;  1PIC A;  4GPL B;  4L1B B;  3VRO A;  2GE9 A;  2Y1N A;  2EYZ A;  2EO6 A;  2Y1M A;  5EG3 B;  1BF5 A;  1JYQ A;  1XA6 A;  3PQZ A;  3K2M A;  3OV1 A;  4K44 A;  1R1S A;  5GJH A;  1O47 A;  2QMS A;  5EEQ A;  5EHP A;  3WA4 A;  3PSJ A;  3IN7 A;  3MXC A;  2YSX A;  1BLJ A;  4A4B A;  2CI9 A;  3S8L A;  3UYO A;  5BO4 A;  1BFI A;  4P9V A;  1AOT F;  2PNB A;  1AYC A;  1FMK A;  3IMD A;  3BUX B;  1FU5 A;  2H46 E;  1AD5 A;  1A07 A;  1KA7 A;  2OZO A;  3VRY A;  5IBM A;  1IJR A;  1LKK A;  3KFJ A;  2ROR A;  4DGX A;  5AXI A;  4JGH A;  1YVL A;  1O4K A;  1JYR A;  4K45 A;  1A08 A;  2HCK A;  1OPK A;  1O4R A;  3VS2 A;  3EAZ A;  2OQ1 A;  1YVH A;  3HCK A;  1D1Z A;  2HDX A;  5GJI A;  4K2R A;  1SHD A;  1BKL A;  1SPR A;  2SRC A;  4E93 A;  1BKM A;  2CRH A;  2IZV A;  1D4T A;  5DC9 A;  1AYB A;  1FU6 A;  1O4B A;  1SHB A;  3S8O A;  4H34 A;  3GXX A;  2HUW A;  4LUD A;  2VIF A;  1HCT B;  1NRV A;  2RMX A;  3ZNI A;  1P13 A;  3VRR A;  3VS4 A;  2C0T A;  2EYY A;  1O4I A;  2ECD A;  2KNO A;  1SKJ A;  4K11 A;  1FHS A;  3GXW A;  4QSY A;  5AUL A;  4OHL A;  4F59 A;  3IMJ A;  1Y1U A;  3N84 A;  1B47 A;  2EO3 A;  3OB1 B;  1M61 A;  1Y57 A;  4H1O A;  3PSK A;  1A1B A;  1HCS B;  3EAC A;  1O4C A;  1O4F A;  1R1Q A;  1MIL A;  4U17 A;  1BLK A;  2LRA A;  3VS1 A;  4OHE A;  4D8K A;  1QAD A;  2MRK A;  1NZV A;  3M7F A;  2HMH A;  1JWO A;  3VS5 A;  4LUE A;  2SHP A;  1TCE A;  3N7Y A;  2JYQ A;  2IUI A;  1GRI A;  3TL0 A;  3BUM B;  2GSB A;  3UF4 A;  3CWG A;  1A1C A;  5HKY A;  1BHF A;  1M27 A;  2AUG A;  1BFJ A;  4F5B A;  2DM0 A;  3S9K A;  1O4J A;  2EU0 A;  2B3O A;  1LUI A;  4XZ0 A;  2IUH A;  1O43 A;  3VRP A;  1KC2 A;  1OPL A;  2MQI A;  3CD3 A;  3QWX X;  1F2F A;  1O41 A;  1O48 A;  2XP1 A;  2CIA A;  5KAZ A;  1CWD L;  2PLD A;  4ROJ A;  1A1A A;  4A4C A;  5D0J A;  1Z3K A;  2MRJ A;  1LKL A;  4FBN A;  4OHI A;  2LNW A;  1A09 A;  1LUN A;  2H8H A;  4JEG A;  1LCJ A;  2IUG A;  1JYU A;  1O4L A;  4M4Z A;  1X27 A;  1K9A A;  2EL8 A;  1LUK A;  1O49 A;  1UUS A;  3MAZ A;  1OO4 A;  1RQQ C;  3OVE A;  4OHH A;  1CWE A;  1RPY A;  2KK6 A;  1X0N A;  1F1W A;  2PTK A;  3MXY A;  3VRZ A;  4E68 A;  1O46 A;  3PS5 A;  3OP0 A;  2FO0 A;  3VS3 A;  3PFV A;  2CS0 A;  1SPS A;  3S8N A;  2YU7 A;  4TZI A;  1FYR A;  3VRN A;  2LQW A;  5EHR A;  1MW4 A;  1BHH B; 
#chains in the Genus database with same CATH homology
 1LCK A;  5CDW A;  4XZ1 A;  1WQU A;  1R1P A;  2H5K A;  1AYD A;  3PLF B;  4GL9 E;  5DC4 A;  1AYA A;  1D4W A;  2LQN A;  2RVF A;  5IBS A;  1AB2 A;  1X6C A;  3VGO A;  1JU5 A;  4JE4 A;  4WWQ A;  1GHU A;  1O44 A;  5HKZ A;  2HDV A;  3IN8 A;  1O4M A;  2FCI A;  1OO3 A;  2L4K A;  1O4Q A;  2PNA A;  2Y3A B;  4P9Z A;  4F5A A;  1O4D A;  4FL3 A;  3N8M A;  5DC0 B;  3NHN A;  3US4 A;  1SHA A;  2L6K A;  1UUR A;  4FL2 A;  1O42 A;  1KSW A;  1O4H A;  1ZFP E;  3T04 A;  2C0O A;  2EKX A;  4EY0 A;  3BKB A;  1KA6 A;  3TKZ A;  1O4E A;  1G83 A;  2AOB A;  5EEL A;  2K7A B;  1LUM A;  1QG1 E;  2LNX A;  5I6V A;  4NWF A;  3CBL A;  1O4N A;  2DLZ A;  3BUO B;  3HIZ B;  3VS0 A;  1A1E A;  3QWY A;  2BBU A;  2C0I A;  2DLY A;  1NZL A;  1I3Z A;  2MC1 A;  1RJA A;  3VS7 A;  1CSZ A;  1BMB A;  1O4P A;  1IS0 A;  3GQI B;  1QCF A;  5DF6 A;  1BM2 A;  4NWG A;  1O4O A;  2EYV A;  1O4G A;  2ETZ A;  2CR4 A;  3HHM B;  3OB2 B;  5J3X A;  2LCT A;  2CBL A;  2MK2 A;  4GWF A;  1AOU F;  3CXL A;  3VS6 A;  2DCR A;  2PLE A;  1FBZ A;  1O45 A;  2L3T A;  1A81 A;  1BG1 A;  2CI8 A;  3BUW B;  2RSY A;  2C9W A;  3VRQ A;  4DGP A;  1FBV A;  3BUN B;  1BHH A;  2AOA A;  1O4A A;  5HKW A;  1H9O A;  4EIH A;  1CJ1 A;  1CSY A;  2EOB A;  4OHD A;  1TZE E;  2DX0 A;  2ABL A;  2K79 B;  3C7I A;  4U1P A;  2DVJ A;  4X6S A;  3PJP A;  1PIC A;  4GPL B;  4L1B B;  3VRO A;  2GE9 A;  2Y1N A;  2EYZ A;  2EO6 A;  2Y1M A;  5EG3 B;  1BF5 A;  1JYQ A;  1XA6 A;  3PQZ A;  3K2M A;  3OV1 A;  4K44 A;  1R1S A;  5GJH A;  1O47 A;  2QMS A;  5EEQ A;  5EHP A;  3WA4 A;  3PSJ A;  3IN7 A;  3MXC A;  2YSX A;  1BLJ A;  4A4B A;  2CI9 A;  3S8L A;  3UYO A;  5BO4 A;  1BFI A;  4P9V A;  1AOT F;  2PNB A;  1AYC A;  1FMK A;  3IMD A;  3BUX B;  1FU5 A;  2H46 E;  1AD5 A;  1A07 A;  1KA7 A;  2OZO A;  3VRY A;  5IBM A;  1IJR A;  1LKK A;  3KFJ A;  2ROR A;  4DGX A;  5AXI A;  4JGH A;  1YVL A;  1O4K A;  1JYR A;  4K45 A;  1A08 A;  2HCK A;  1OPK A;  1O4R A;  3VS2 A;  3EAZ A;  2OQ1 A;  1YVH A;  3HCK A;  1D1Z A;  2HDX A;  5GJI A;  4K2R A;  1SHD A;  1BKL A;  1SPR A;  2SRC A;  4E93 A;  1BKM A;  2CRH A;  2IZV A;  1D4T A;  5DC9 A;  1AYB A;  1FU6 A;  1O4B A;  1SHB A;  3S8O A;  4H34 A;  3GXX A;  2HUW A;  4LUD A;  2VIF A;  1HCT B;  1NRV A;  2RMX A;  3ZNI A;  1P13 A;  3VRR A;  3VS4 A;  2C0T A;  2EYY A;  1O4I A;  2ECD A;  2KNO A;  1SKJ A;  4K11 A;  1FHS A;  3GXW A;  4QSY A;  5AUL A;  4OHL A;  4F59 A;  3IMJ A;  1Y1U A;  3N84 A;  1B47 A;  2EO3 A;  3OB1 B;  1M61 A;  1Y57 A;  4H1O A;  3PSK A;  1A1B A;  1HCS B;  3EAC A;  1O4C A;  1O4F A;  1R1Q A;  1MIL A;  4U17 A;  1BLK A;  3VS1 A;  4OHE A;  4D8K A;  1QAD A;  2MRK A;  1NZV A;  3M7F A;  2HMH A;  1JWO A;  3VS5 A;  4LUE A;  2SHP A;  1TCE A;  3N7Y A;  2JYQ A;  2IUI A;  1GRI A;  3TL0 A;  3BUM B;  2GSB A;  3UF4 A;  3CWG A;  1A1C A;  5HKY A;  1BHF A;  1M27 A;  2AUG A;  1BFJ A;  4F5B A;  2DM0 A;  3S9K A;  1O4J A;  2EU0 A;  2B3O A;  1LUI A;  4XZ0 A;  2IUH A;  1O43 A;  3VRP A;  1KC2 A;  1OPL A;  2MQI A;  3CD3 A;  3QWX X;  1F2F A;  1O41 A;  1O48 A;  2XP1 A;  2CIA A;  5KAZ A;  1CWD L;  2PLD A;  4ROJ A;  1A1A A;  4A4C A;  5D0J A;  1Z3K A;  2MRJ A;  1LKL A;  4FBN A;  4OHI A;  2LNW A;  1A09 A;  1LUN A;  2H8H A;  4JEG A;  1LCJ A;  2IUG A;  1JYU A;  1O4L A;  4M4Z A;  1X27 A;  1K9A A;  2EL8 A;  1LUK A;  1O49 A;  1UUS A;  3MAZ A;  1OO4 A;  1RQQ C;  3OVE A;  4OHH A;  1CWE A;  1RPY A;  2KK6 A;  1X0N A;  1F1W A;  2PTK A;  3MXY A;  3VRZ A;  4E68 A;  1O46 A;  3PS5 A;  3OP0 A;  2FO0 A;  3VS3 A;  3PFV A;  2CS0 A;  1SPS A;  3S8N A;  2YU7 A;  4TZI A;  1FYR A;  3VRN A;  2LQW A;  5EHR A;  1MW4 A;  1BHH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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