3IN7A

Crystal structure of the grb2 sh2 domain in complex with a cyclopropyl-constrained ac-py-q-n-nh2 tripeptide mimic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
99
structure length
99
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule tags Signaling protein/peptide
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 99
sequence length 99
chains with identical sequence C
ec nomenclature
pdb deposition date 2009-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3in7A00
1QADA 1M61A 1BFIA 3WA4A 3PSKA 3N84A 1JYUA 1P13A 1SPSA 2LNXA 3VGOA 1BM2A 1NZLA 2AOAA 4OHIA 1FBVA 1R1PA 3VS0A 3EACA 2PLEA 3T04A 5EHPA 4FL2A 2KNOA 4QSYA 1BKLA 1SKJA 1CJ1A 3TKZA 1O4JA 4TZIA 3C7IA 4DGPA 1IJRA 1PICA 5AULA 2EU0A 2OQ1A 4FBNA 5IBMA 1FU6A 4D8KA 3NHNA 1O4RA 2SRCA 3S8NA 2RORA 1O4EA 1O4MA 1O4CA 4OHDA 1YVLA 1LUMA 1FBZA 2C0IA 4F59A 1O4BA 1Y1UA 2MK2A 2AOBA 2XP1A 1KA7A 2PNAA 2RMXA 1GRIA 4EY0A 1D1ZA 3OV1A 1LKLA 4JEGA 1AYDA 5KAZA 1BG1A 3PLFB 4F5AA 3BUMB 1JU5A 1AB2A 1TZEE 1O4GA 1O41A 2HDXA 4GL9E 1AOTF 2EYYA 1R1SA 4A4CA 3VRRA 1WQUA 3IN7A 3VS3A 2DVJA 1NZVA 2PNBA 1UUSA 5I6VA 3GXWA 3HIZB 5CDWA 1TCEA 1O4PA 1BFJA 4K45A 4ROJA 1SHAA 3VS1A 3PJPA 1LKKA 2C9WA 1NRVA 1BHHB 5GJIA 3OB1B 4U1PA 1A07A 2EYVA 2L3TA 2EYZA 4K44A 4OHEA 1K9AA 1MW4A 2OZOA 4M4ZA 2ECDA 2CI9A 3MAZA 4E93A 4DGXA 1LUIA 5IBSA 4H34A 4P9VA 1O4AA 1JYQA 1O47A 3S9KA 5DC9A 2QMSA 4NWGA 2Y1NA 1KSWA 1QCFA 3PS5A 1QG1E 4NWFA 2IUGA 2YU7A 4EIHA 1X6CA 1O4DA 1FYRA 5AXIA 1LUKA 1F2FA 1BLKA 2H8HA 2C0OA 3QWYA 1A81A 2DX0A 2CS0A 2MQIA 1BLJA 4GPLB 3OB2B 4OHHA 2EO6A 1SHDA 1B47A 1O4FA 2EL8A 1FU5A 2LCTA 3UF4A 1OPKA 2EKXA 2IUIA 2CRHA 1BHFA 1CWEA 3K2MA 1KA6A 4U17A 3BUOB 3VS6A 4P9ZA 3OVEA 3OP0A 3HCKA 1GHUA 1O45A 5DC4A 1O44A 2KK6A 1A1EA 2H5KA 3PQZA 4WWQA 1F1WA 3M7FA 2L6KA 5HKWA 1AD5A 2BBUA 1UURA 1O4LA 1BKMA 2DLZA 4OHLA 1IS0A 2IUHA 1A1BA 3EAZA 3KFJA 1O4KA 2L4KA 2DM0A 1A08A 1RPYA 4F5BA 2H46E 2MRJA 2ABLA 2MRKA 1AYAA 3PSJA 1CWDL 1FMKA 1O49A 3MXCA 1CSYA 3QWXX 2LNWA 1O4OA 1Z3KA 3VROA 2VIFA 2YSXA 3S8LA 5GJHA 2PLDA 5EEQA 1X27A 5J3XA 2Y3AB 2GE9A 1Y57A 2RVFA 5D0JA 4H1OA 2EOBA 1HCTB 3VS7A 3S8OA 4A4BA 1D4WA 1O4IA 5HKYA 2GSBA 3CXLA 1O46A 2CIAA 1G83A 5DF6A 1SHBA 3HHMB 1BHHA 1O4QA 5EELA 1MILA 1RJAA 2JYQA 3GXXA 1XA6A 1CSZA 2HDVA 1R1QA 4XZ0A 3UYOA 3IMDA 2CI8A 1YVHA 1OO4A 2EO3A 1ZFPE 2ETZA 2HCKA 1JWOA 4XZ1A 2RSYA 2K79B 2DCRA 3ZNIA 1I3ZA 1O43A 3CD3A 1AYBA 3VRQA 3VRZA 3IN8A 5DC0B 1RQQC 2AUGA 3TL0A 1JYRA 2Y1MA 2LQNA 3US4A 2K7AB 2CBLA 1LCJA 1H9OA 2IZVA 2PTKA 2B3OA 2LQWA 3VRPA 2DLYA 4LUDA 3MXYA 4E68A 1A1AA 1M27A 3CWGA 4JGHA 1LCKA 1X0NA 3VS4A 3VRNA 2SHPA 1LUNA 2MC1A 1AOUF 3CBLA 4K11A 3N8MA 1OPLA 3PFVA 5EHRA 4GWFA 1OO3A 4FL3A 5BO4A 4LUEA 2HMHA 1A1CA 4L1BB 3BUXB 1SPRA 1O4HA 3BUNB 3VS2A 1FHSA 2FCIA 3VS5A 3GQIB 1BF5A 1AYCA 1KC2A 2C0TA 1O42A 2HUWA 3IMJA 3VRYA 5EG3B 2CR4A 1A09A 2FO0A 4K2RA 1BMBA 3N7YA 3BKBA 4JE4A 1O4NA 5HKZA 1HCSB 1D4TA 1O48A 4X6SA 3BUWB
chains in the Genus database with same CATH superfamily
1QADA 1M61A 1BFIA 3WA4A 3PSKA 3N84A 1JYUA 1P13A 1SPSA 2LNXA 3VGOA 1BM2A 1NZLA 2AOAA 4OHIA 1FBVA 1R1PA 3VS0A 3EACA 2PLEA 3T04A 5EHPA 4FL2A 2KNOA 4QSYA 1BKLA 1SKJA 1CJ1A 3TKZA 1O4JA 4TZIA 3C7IA 4DGPA 1IJRA 1PICA 5AULA 2EU0A 2OQ1A 4FBNA 5IBMA 1FU6A 4D8KA 3NHNA 1O4RA 2SRCA 3S8NA 2RORA 1O4EA 1O4MA 1O4CA 3LYVA 1YVLA 4OHDA 1LUMA 1FBZA 2C0IA 4F59A 1O4BA 1Y1UA 2MK2A 2AOBA 2XP1A 1KA7A 2PNAA 2RMXA 1GRIA 4EY0A 1D1ZA 3OV1A 1LKLA 4JEGA 1AYDA 5KAZA 1BG1A 3PLFB 4F5AA 3BUMB 1JU5A 1AB2A 1TZEE 1O4GA 1O41A 2HDXA 4GL9E 1AOTF 2EYYA 1R1SA 4A4CA 3VRRA 1WQUA 3IN7A 3VS3A 2DVJA 1NZVA 2PNBA 1UUSA 5I6VA 3GXWA 3HIZB 5CDWA 1TCEA 1O4PA 1BFJA 4K45A 4ROJA 1SHAA 3VS1A 3PJPA 1LKKA 2C9WA 1NRVA 1BHHB 5GJIA 3OB1B 4U1PA 1A07A 2EYVA 2L3TA 2EYZA 4K44A 4OHEA 1K9AA 1MW4A 2OZOA 4M4ZA 3K2TA 2ECDA 2CI9A 3MAZA 4E93A 4DGXA 1LUIA 5IBSA 4H34A 4P9VA 1O4AA 1JYQA 1O47A 3S9KA 5DC9A 2QMSA 4NWGA 2Y1NA 1KSWA 1QCFA 3PS5A 1QG1E 4NWFA 2IUGA 2YU7A 4EIHA 1X6CA 1O4DA 1FYRA 5AXIA 1LUKA 1F2FA 1BLKA 2H8HA 2C0OA 3QWYA 1A81A 2DX0A 2CS0A 2MQIA 1BLJA 4GPLB 3OB2B 4OHHA 2EO6A 1SHDA 1B47A 1O4FA 2EL8A 1FU5A 2LCTA 3UF4A 1OPKA 2EKXA 2IUIA 2CRHA 1BHFA 1CWEA 2LRAA 3K2MA 1KA6A 4U17A 3BUOB 3VS6A 4P9ZA 3OVEA 3OP0A 3HCKA 1GHUA 1O45A 5DC4A 1O44A 2KK6A 1A1EA 2H5KA 3PQZA 4WWQA 1F1WA 3M7FA 2L6KA 5HKWA 1AD5A 2BBUA 1UURA 1O4LA 1BKMA 2DLZA 4OHLA 1IS0A 2IUHA 1A1BA 3EAZA 3KFJA 1O4KA 2L4KA 2DM0A 1A08A 1RPYA 4F5BA 2H46E 2MRJA 2ABLA 2MRKA 1AYAA 3PSJA 1CWDL 1FMKA 1O49A 3MXCA 1CSYA 3QWXX 2LNWA 1O4OA 1Z3KA 3VROA 2VIFA 2YSXA 3S8LA 5GJHA 2PLDA 5EEQA 1X27A 5J3XA 2Y3AB 2GE9A 1Y57A 2RVFA 5D0JA 4H1OA 2EOBA 1HCTB 3VS7A 3S8OA 4A4BA 1D4WA 1O4IA 5HKYA 2GSBA 3CXLA 1O46A 2CIAA 1G83A 5DF6A 1SHBA 3HHMB 1BHHA 1O4QA 5EELA 1MILA 1RJAA 2JYQA 3GXXA 1XA6A 1CSZA 2HDVA 1R1QA 4XZ0A 3UYOA 3IMDA 2CI8A 1YVHA 1OO4A 2EO3A 1ZFPE 2ETZA 2HCKA 1JWOA 4XZ1A 2RSYA 2K79B 2DCRA 3ZNIA 1I3ZA 1O43A 3CD3A 1AYBA 3VRQA 3VRZA 3IN8A 5DC0B 1RQQC 2AUGA 3TL0A 1JYRA 2Y1MA 2LQNA 3US4A 2K7AB 2CBLA 1LCJA 1H9OA 2IZVA 2PTKA 2B3OA 2LQWA 3VRPA 2DLYA 4LUDA 3MXYA 4E68A 1A1AA 1M27A 3CWGA 4JGHA 1LCKA 1X0NA 3VS4A 3VRNA 2SHPA 1LUNA 2MC1A 1AOUF 3CBLA 4K11A 3N8MA 1OPLA 3PFVA 5EHRA 4GWFA 2KGYA 1OO3A 4FL3A 5BO4A 4LUEA 2HMHA 1A1CA 4L1BB 3BUXB 1SPRA 1O4HA 3BUNB 3VS2A 1FHSA 2FCIA 3VS5A 3GQIB 1BF5A 1AYCA 1KC2A 2C0TA 1O42A 2HUWA 3IMJA 3VRYA 5EG3B 2CR4A 1A09A 2FO0A 4K2RA 1BMBA 3N7YA 3BKBA 4JE4A 1O4NA 5HKZA 1HCSB 1D4TA 1O48A 4X6SA 3BUWB
chains in the Genus database with same CATH topology
1QADA 1M61A 1BFIA 3WA4A 3PSKA 3N84A 1JYUA 1P13A 1SPSA 2LNXA 3VGOA 1BM2A 1NZLA 2AOAA 4OHIA 1FBVA 1R1PA 3VS0A 3EACA 2PLEA 3T04A 5EHPA 4FL2A 2KNOA 4QSYA 1BKLA 1SKJA 1CJ1A 3TKZA 1O4JA 4TZIA 3C7IA 4DGPA 1IJRA 1PICA 5AULA 2EU0A 2OQ1A 4FBNA 5IBMA 1FU6A 4D8KA 3NHNA 1O4RA 2SRCA 3S8NA 2RORA 1O4EA 1O4MA 1O4CA 4OHDA 1YVLA 1LUMA 1FBZA 2C0IA 4F59A 1O4BA 1Y1UA 2MK2A 2AOBA 2XP1A 1KA7A 2PNAA 2RMXA 1GRIA 4EY0A 1D1ZA 3OV1A 1LKLA 4JEGA 1AYDA 5KAZA 1BG1A 3PLFB 4F5AA 3BUMB 1JU5A 1AB2A 1TZEE 1O4GA 1O41A 2HDXA 4GL9E 1AOTF 2EYYA 1R1SA 4A4CA 3VRRA 1WQUA 3IN7A 3VS3A 2DVJA 1NZVA 2PNBA 1UUSA 5I6VA 3GXWA 3HIZB 5CDWA 1TCEA 1O4PA 1BFJA 4K45A 4ROJA 1SHAA 3VS1A 3PJPA 1LKKA 2C9WA 1NRVA 1BHHB 5GJIA 3OB1B 4U1PA 1A07A 2EYVA 2L3TA 2EYZA 4K44A 4OHEA 1K9AA 1MW4A 2OZOA 4M4ZA 2ECDA 2CI9A 3MAZA 4E93A 4DGXA 1LUIA 5IBSA 4H34A 4P9VA 1O4AA 1JYQA 1O47A 3S9KA 5DC9A 2QMSA 4NWGA 2Y1NA 1KSWA 1QCFA 3PS5A 1QG1E 4NWFA 2IUGA 2YU7A 4EIHA 1X6CA 1O4DA 1FYRA 5AXIA 1LUKA 1F2FA 1BLKA 2H8HA 2C0OA 3QWYA 1A81A 2DX0A 2CS0A 2MQIA 1BLJA 4GPLB 3OB2B 4OHHA 2EO6A 1SHDA 1B47A 1O4FA 2EL8A 1FU5A 2LCTA 3UF4A 1OPKA 2EKXA 2IUIA 2CRHA 1BHFA 1CWEA 3K2MA 1KA6A 4U17A 3BUOB 3VS6A 4P9ZA 3OVEA 3OP0A 3HCKA 1GHUA 1O45A 5DC4A 1O44A 2KK6A 1A1EA 2H5KA 3PQZA 4WWQA 1F1WA 3M7FA 2L6KA 5HKWA 1AD5A 2BBUA 1UURA 1O4LA 1BKMA 2DLZA 4OHLA 1IS0A 2IUHA 1A1BA 3EAZA 3KFJA 1O4KA 2L4KA 2DM0A 1A08A 1RPYA 4F5BA 2H46E 2MRJA 2ABLA 2MRKA 1AYAA 3PSJA 1CWDL 1FMKA 1O49A 3MXCA 1CSYA 3QWXX 2LNWA 1O4OA 1Z3KA 3VROA 2VIFA 2YSXA 3S8LA 5GJHA 2PLDA 5EEQA 1X27A 5J3XA 2Y3AB 2GE9A 1Y57A 2RVFA 5D0JA 4H1OA 2EOBA 1HCTB 3VS7A 3S8OA 4A4BA 1D4WA 1O4IA 5HKYA 2GSBA 3CXLA 1O46A 2CIAA 1G83A 5DF6A 1SHBA 3HHMB 1BHHA 1O4QA 5EELA 1MILA 1RJAA 2JYQA 3GXXA 1XA6A 1CSZA 2HDVA 1R1QA 4XZ0A 3UYOA 3IMDA 2CI8A 1YVHA 1OO4A 2EO3A 1ZFPE 2ETZA 2HCKA 1JWOA 4XZ1A 2RSYA 2K79B 2DCRA 3ZNIA 1I3ZA 1O43A 3CD3A 1AYBA 3VRQA 3VRZA 3IN8A 5DC0B 1RQQC 2AUGA 3TL0A 1JYRA 2Y1MA 2LQNA 3US4A 2K7AB 2CBLA 1LCJA 1H9OA 2IZVA 2PTKA 2B3OA 2LQWA 3VRPA 2DLYA 4LUDA 3MXYA 4E68A 1A1AA 1M27A 3CWGA 4JGHA 1LCKA 1X0NA 3VS4A 3VRNA 2SHPA 1LUNA 2MC1A 1AOUF 3CBLA 4K11A 3N8MA 1OPLA 3PFVA 5EHRA 4GWFA 1OO3A 4FL3A 5BO4A 4LUEA 2HMHA 1A1CA 4L1BB 3BUXB 1SPRA 1O4HA 3BUNB 3VS2A 1FHSA 2FCIA 3VS5A 3GQIB 1BF5A 1AYCA 1KC2A 2C0TA 1O42A 2HUWA 3IMJA 3VRYA 5EG3B 2CR4A 1A09A 2FO0A 4K2RA 1BMBA 3N7YA 3BKBA 4JE4A 1O4NA 5HKZA 1HCSB 1D4TA 1O48A 4X6SA 3BUWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QAD A;  1M61 A;  1BFI A;  3WA4 A;  3PSK A;  3N84 A;  1JYU A;  1P13 A;  1SPS A;  2LNX A;  3VGO A;  1BM2 A;  1NZL A;  2AOA A;  4OHI A;  1FBV A;  1R1P A;  3VS0 A;  3EAC A;  2PLE A;  3T04 A;  5EHP A;  4FL2 A;  2KNO A;  4QSY A;  1BKL A;  1SKJ A;  1CJ1 A;  3TKZ A;  1O4J A;  4TZI A;  3C7I A;  4DGP A;  1IJR A;  1PIC A;  5AUL A;  2EU0 A;  2OQ1 A;  4FBN A;  5IBM A;  1FU6 A;  4D8K A;  3NHN A;  1O4R A;  2SRC A;  3S8N A;  2ROR A;  1O4E A;  1O4M A;  1O4C A;  4OHD A;  1YVL A;  1LUM A;  1FBZ A;  2C0I A;  4F59 A;  1O4B A;  1Y1U A;  2MK2 A;  2AOB A;  2XP1 A;  1KA7 A;  2PNA A;  2RMX A;  1GRI A;  4EY0 A;  1D1Z A;  3OV1 A;  1LKL A;  4JEG A;  1AYD A;  5KAZ A;  1BG1 A;  3PLF B;  4F5A A;  3BUM B;  1JU5 A;  1AB2 A;  1TZE E;  1O4G A;  1O41 A;  2HDX A;  4GL9 E;  1AOT F;  2EYY A;  1R1S A;  4A4C A;  3VRR A;  1WQU A;  3IN7 A;  3VS3 A;  2DVJ A;  1NZV A;  2PNB A;  1UUS A;  5I6V A;  3GXW A;  3HIZ B;  5CDW A;  1TCE A;  1O4P A;  1BFJ A;  4K45 A;  4ROJ A;  1SHA A;  3VS1 A;  3PJP A;  1LKK A;  2C9W A;  1NRV A;  1BHH B;  5GJI A;  3OB1 B;  4U1P A;  1A07 A;  2EYV A;  2L3T A;  2EYZ A;  4K44 A;  4OHE A;  1K9A A;  1MW4 A;  2OZO A;  4M4Z A;  2ECD A;  2CI9 A;  3MAZ A;  4E93 A;  4DGX A;  1LUI A;  5IBS A;  4H34 A;  4P9V A;  1O4A A;  1JYQ A;  1O47 A;  3S9K A;  5DC9 A;  2QMS A;  4NWG A;  2Y1N A;  1KSW A;  1QCF A;  3PS5 A;  1QG1 E;  4NWF A;  2IUG A;  2YU7 A;  4EIH A;  1X6C A;  1O4D A;  1FYR A;  5AXI A;  1LUK A;  1F2F A;  1BLK A;  2H8H A;  2C0O A;  3QWY A;  1A81 A;  2DX0 A;  2CS0 A;  2MQI A;  1BLJ A;  4GPL B;  3OB2 B;  4OHH A;  2EO6 A;  1SHD A;  1B47 A;  1O4F A;  2EL8 A;  1FU5 A;  2LCT A;  3UF4 A;  1OPK A;  2EKX A;  2IUI A;  2CRH A;  1BHF A;  1CWE A;  3K2M A;  1KA6 A;  4U17 A;  3BUO B;  3VS6 A;  4P9Z A;  3OVE A;  3OP0 A;  3HCK A;  1GHU A;  1O45 A;  5DC4 A;  1O44 A;  2KK6 A;  1A1E A;  2H5K A;  3PQZ A;  4WWQ A;  1F1W A;  3M7F A;  2L6K A;  5HKW A;  1AD5 A;  2BBU A;  1UUR A;  1O4L A;  1BKM A;  2DLZ A;  4OHL A;  1IS0 A;  2IUH A;  1A1B A;  3EAZ A;  3KFJ A;  1O4K A;  2L4K A;  2DM0 A;  1A08 A;  1RPY A;  4F5B A;  2H46 E;  2MRJ A;  2ABL A;  2MRK A;  1AYA A;  3PSJ A;  1CWD L;  1FMK A;  1O49 A;  3MXC A;  1CSY A;  3QWX X;  2LNW A;  1O4O A;  1Z3K A;  3VRO A;  2VIF A;  2YSX A;  3S8L A;  5GJH A;  2PLD A;  5EEQ A;  1X27 A;  5J3X A;  2Y3A B;  2GE9 A;  1Y57 A;  2RVF A;  5D0J A;  4H1O A;  2EOB A;  1HCT B;  3VS7 A;  3S8O A;  4A4B A;  1D4W A;  1O4I A;  5HKY A;  2GSB A;  3CXL A;  1O46 A;  2CIA A;  1G83 A;  5DF6 A;  1SHB A;  3HHM B;  1BHH A;  1O4Q A;  5EEL A;  1MIL A;  1RJA A;  2JYQ A;  3GXX A;  1XA6 A;  1CSZ A;  2HDV A;  1R1Q A;  4XZ0 A;  3UYO A;  3IMD A;  2CI8 A;  1YVH A;  1OO4 A;  2EO3 A;  1ZFP E;  2ETZ A;  2HCK A;  1JWO A;  4XZ1 A;  2RSY A;  2K79 B;  2DCR A;  3ZNI A;  1I3Z A;  1O43 A;  3CD3 A;  1AYB A;  3VRQ A;  3VRZ A;  3IN8 A;  5DC0 B;  1RQQ C;  2AUG A;  3TL0 A;  1JYR A;  2Y1M A;  2LQN A;  3US4 A;  2K7A B;  2CBL A;  1LCJ A;  1H9O A;  2IZV A;  2PTK A;  2B3O A;  2LQW A;  3VRP A;  2DLY A;  4LUD A;  3MXY A;  4E68 A;  1A1A A;  1M27 A;  3CWG A;  4JGH A;  1LCK A;  1X0N A;  3VS4 A;  3VRN A;  2SHP A;  1LUN A;  2MC1 A;  1AOU F;  3CBL A;  4K11 A;  3N8M A;  1OPL A;  3PFV A;  5EHR A;  4GWF A;  1OO3 A;  4FL3 A;  5BO4 A;  4LUE A;  2HMH A;  1A1C A;  4L1B B;  3BUX B;  1SPR A;  1O4H A;  3BUN B;  3VS2 A;  1FHS A;  2FCI A;  3VS5 A;  3GQI B;  1BF5 A;  1AYC A;  1KC2 A;  2C0T A;  1O42 A;  2HUW A;  3IMJ A;  3VRY A;  5EG3 B;  2CR4 A;  1A09 A;  2FO0 A;  4K2R A;  1BMB A;  3N7Y A;  3BKB A;  4JE4 A;  1O4N A;  5HKZ A;  1HCS B;  1D4T A;  1O48 A;  4X6S A;  3BUW B; 
#chains in the Genus database with same CATH topology
 1QAD A;  1M61 A;  1BFI A;  3WA4 A;  3PSK A;  3N84 A;  1JYU A;  1P13 A;  1SPS A;  2LNX A;  3VGO A;  1BM2 A;  1NZL A;  2AOA A;  4OHI A;  1FBV A;  1R1P A;  3VS0 A;  3EAC A;  2PLE A;  3T04 A;  5EHP A;  4FL2 A;  2KNO A;  4QSY A;  1BKL A;  1SKJ A;  1CJ1 A;  3TKZ A;  1O4J A;  4TZI A;  3C7I A;  4DGP A;  1IJR A;  1PIC A;  5AUL A;  2EU0 A;  2OQ1 A;  4FBN A;  5IBM A;  1FU6 A;  4D8K A;  3NHN A;  1O4R A;  2SRC A;  3S8N A;  2ROR A;  1O4E A;  1O4M A;  1O4C A;  3LYV A;  1YVL A;  4OHD A;  1LUM A;  1FBZ A;  2C0I A;  4F59 A;  1O4B A;  1Y1U A;  2MK2 A;  2AOB A;  2XP1 A;  1KA7 A;  2PNA A;  2RMX A;  1GRI A;  4EY0 A;  1D1Z A;  3OV1 A;  1LKL A;  4JEG A;  1AYD A;  5KAZ A;  1BG1 A;  3PLF B;  4F5A A;  3BUM B;  1JU5 A;  1AB2 A;  1TZE E;  1O4G A;  1O41 A;  2HDX A;  4GL9 E;  1AOT F;  2EYY A;  1R1S A;  4A4C A;  3VRR A;  1WQU A;  3IN7 A;  3VS3 A;  2DVJ A;  1NZV A;  2PNB A;  1UUS A;  5I6V A;  3GXW A;  3HIZ B;  5CDW A;  1TCE A;  1O4P A;  1BFJ A;  4K45 A;  4ROJ A;  1SHA A;  3VS1 A;  3PJP A;  1LKK A;  2C9W A;  1NRV A;  1BHH B;  5GJI A;  3OB1 B;  4U1P A;  1A07 A;  2EYV A;  2L3T A;  2EYZ A;  4K44 A;  4OHE A;  1K9A A;  1MW4 A;  2OZO A;  4M4Z A;  3K2T A;  2ECD A;  2CI9 A;  3MAZ A;  4E93 A;  4DGX A;  1LUI A;  5IBS A;  4H34 A;  4P9V A;  1O4A A;  1JYQ A;  1O47 A;  3S9K A;  5DC9 A;  2QMS A;  4NWG A;  2Y1N A;  1KSW A;  1QCF A;  3PS5 A;  1QG1 E;  4NWF A;  2IUG A;  2YU7 A;  4EIH A;  1X6C A;  1O4D A;  1FYR A;  5AXI A;  1LUK A;  1F2F A;  1BLK A;  2H8H A;  2C0O A;  3QWY A;  1A81 A;  2DX0 A;  2CS0 A;  2MQI A;  1BLJ A;  4GPL B;  3OB2 B;  4OHH A;  2EO6 A;  1SHD A;  1B47 A;  1O4F A;  2EL8 A;  1FU5 A;  2LCT A;  3UF4 A;  1OPK A;  2EKX A;  2IUI A;  2CRH A;  1BHF A;  1CWE A;  2LRA A;  3K2M A;  1KA6 A;  4U17 A;  3BUO B;  3VS6 A;  4P9Z A;  3OVE A;  3OP0 A;  3HCK A;  1GHU A;  1O45 A;  5DC4 A;  1O44 A;  2KK6 A;  1A1E A;  2H5K A;  3PQZ A;  4WWQ A;  1F1W A;  3M7F A;  2L6K A;  5HKW A;  1AD5 A;  2BBU A;  1UUR A;  1O4L A;  1BKM A;  2DLZ A;  4OHL A;  1IS0 A;  2IUH A;  1A1B A;  3EAZ A;  3KFJ A;  1O4K A;  2L4K A;  2DM0 A;  1A08 A;  1RPY A;  4F5B A;  2H46 E;  2MRJ A;  2ABL A;  2MRK A;  1AYA A;  3PSJ A;  1CWD L;  1FMK A;  1O49 A;  3MXC A;  1CSY A;  3QWX X;  2LNW A;  1O4O A;  1Z3K A;  3VRO A;  2VIF A;  2YSX A;  3S8L A;  5GJH A;  2PLD A;  5EEQ A;  1X27 A;  5J3X A;  2Y3A B;  2GE9 A;  1Y57 A;  2RVF A;  5D0J A;  4H1O A;  2EOB A;  1HCT B;  3VS7 A;  3S8O A;  4A4B A;  1D4W A;  1O4I A;  5HKY A;  2GSB A;  3CXL A;  1O46 A;  2CIA A;  1G83 A;  5DF6 A;  1SHB A;  3HHM B;  1BHH A;  1O4Q A;  5EEL A;  1MIL A;  1RJA A;  2JYQ A;  3GXX A;  1XA6 A;  1CSZ A;  2HDV A;  1R1Q A;  4XZ0 A;  3UYO A;  3IMD A;  2CI8 A;  1YVH A;  1OO4 A;  2EO3 A;  1ZFP E;  2ETZ A;  2HCK A;  1JWO A;  4XZ1 A;  2RSY A;  2K79 B;  2DCR A;  3ZNI A;  1I3Z A;  1O43 A;  3CD3 A;  1AYB A;  3VRQ A;  3VRZ A;  3IN8 A;  5DC0 B;  1RQQ C;  2AUG A;  3TL0 A;  1JYR A;  2Y1M A;  2LQN A;  3US4 A;  2K7A B;  2CBL A;  1LCJ A;  1H9O A;  2IZV A;  2PTK A;  2B3O A;  2LQW A;  3VRP A;  2DLY A;  4LUD A;  3MXY A;  4E68 A;  1A1A A;  1M27 A;  3CWG A;  4JGH A;  1LCK A;  1X0N A;  3VS4 A;  3VRN A;  2SHP A;  1LUN A;  2MC1 A;  1AOU F;  3CBL A;  4K11 A;  3N8M A;  1OPL A;  3PFV A;  5EHR A;  4GWF A;  2KGY A;  1OO3 A;  4FL3 A;  5BO4 A;  4LUE A;  2HMH A;  1A1C A;  4L1B B;  3BUX B;  1SPR A;  1O4H A;  3BUN B;  3VS2 A;  1FHS A;  2FCI A;  3VS5 A;  3GQI B;  1BF5 A;  1AYC A;  1KC2 A;  2C0T A;  1O42 A;  2HUW A;  3IMJ A;  3VRY A;  5EG3 B;  2CR4 A;  1A09 A;  2FO0 A;  4K2R A;  1BMB A;  3N7Y A;  3BKB A;  4JE4 A;  1O4N A;  5HKZ A;  1HCS B;  1D4T A;  1O48 A;  4X6S A;  3BUW B; 
#chains in the Genus database with same CATH homology
 1QAD A;  1M61 A;  1BFI A;  3WA4 A;  3PSK A;  3N84 A;  1JYU A;  1P13 A;  1SPS A;  2LNX A;  3VGO A;  1BM2 A;  1NZL A;  2AOA A;  4OHI A;  1FBV A;  1R1P A;  3VS0 A;  3EAC A;  2PLE A;  3T04 A;  5EHP A;  4FL2 A;  2KNO A;  4QSY A;  1BKL A;  1SKJ A;  1CJ1 A;  3TKZ A;  1O4J A;  4TZI A;  3C7I A;  4DGP A;  1IJR A;  1PIC A;  5AUL A;  2EU0 A;  2OQ1 A;  4FBN A;  5IBM A;  1FU6 A;  4D8K A;  3NHN A;  1O4R A;  2SRC A;  3S8N A;  2ROR A;  1O4E A;  1O4M A;  1O4C A;  4OHD A;  1YVL A;  1LUM A;  1FBZ A;  2C0I A;  4F59 A;  1O4B A;  1Y1U A;  2MK2 A;  2AOB A;  2XP1 A;  1KA7 A;  2PNA A;  2RMX A;  1GRI A;  4EY0 A;  1D1Z A;  3OV1 A;  1LKL A;  4JEG A;  1AYD A;  5KAZ A;  1BG1 A;  3PLF B;  4F5A A;  3BUM B;  1JU5 A;  1AB2 A;  1TZE E;  1O4G A;  1O41 A;  2HDX A;  4GL9 E;  1AOT F;  2EYY A;  1R1S A;  4A4C A;  3VRR A;  1WQU A;  3IN7 A;  3VS3 A;  2DVJ A;  1NZV A;  2PNB A;  1UUS A;  5I6V A;  3GXW A;  3HIZ B;  5CDW A;  1TCE A;  1O4P A;  1BFJ A;  4K45 A;  4ROJ A;  1SHA A;  3VS1 A;  3PJP A;  1LKK A;  2C9W A;  1NRV A;  1BHH B;  5GJI A;  3OB1 B;  4U1P A;  1A07 A;  2EYV A;  2L3T A;  2EYZ A;  4K44 A;  4OHE A;  1K9A A;  1MW4 A;  2OZO A;  4M4Z A;  2ECD A;  2CI9 A;  3MAZ A;  4E93 A;  4DGX A;  1LUI A;  5IBS A;  4H34 A;  4P9V A;  1O4A A;  1JYQ A;  1O47 A;  3S9K A;  5DC9 A;  2QMS A;  4NWG A;  2Y1N A;  1KSW A;  1QCF A;  3PS5 A;  1QG1 E;  4NWF A;  2IUG A;  2YU7 A;  4EIH A;  1X6C A;  1O4D A;  1FYR A;  5AXI A;  1LUK A;  1F2F A;  1BLK A;  2H8H A;  2C0O A;  3QWY A;  1A81 A;  2DX0 A;  2CS0 A;  2MQI A;  1BLJ A;  4GPL B;  3OB2 B;  4OHH A;  2EO6 A;  1SHD A;  1B47 A;  1O4F A;  2EL8 A;  1FU5 A;  2LCT A;  3UF4 A;  1OPK A;  2EKX A;  2IUI A;  2CRH A;  1BHF A;  1CWE A;  3K2M A;  1KA6 A;  4U17 A;  3BUO B;  3VS6 A;  4P9Z A;  3OVE A;  3OP0 A;  3HCK A;  1GHU A;  1O45 A;  5DC4 A;  1O44 A;  2KK6 A;  1A1E A;  2H5K A;  3PQZ A;  4WWQ A;  1F1W A;  3M7F A;  2L6K A;  5HKW A;  1AD5 A;  2BBU A;  1UUR A;  1O4L A;  1BKM A;  2DLZ A;  4OHL A;  1IS0 A;  2IUH A;  1A1B A;  3EAZ A;  3KFJ A;  1O4K A;  2L4K A;  2DM0 A;  1A08 A;  1RPY A;  4F5B A;  2H46 E;  2MRJ A;  2ABL A;  2MRK A;  1AYA A;  3PSJ A;  1CWD L;  1FMK A;  1O49 A;  3MXC A;  1CSY A;  3QWX X;  2LNW A;  1O4O A;  1Z3K A;  3VRO A;  2VIF A;  2YSX A;  3S8L A;  5GJH A;  2PLD A;  5EEQ A;  1X27 A;  5J3X A;  2Y3A B;  2GE9 A;  1Y57 A;  2RVF A;  5D0J A;  4H1O A;  2EOB A;  1HCT B;  3VS7 A;  3S8O A;  4A4B A;  1D4W A;  1O4I A;  5HKY A;  2GSB A;  3CXL A;  1O46 A;  2CIA A;  1G83 A;  5DF6 A;  1SHB A;  3HHM B;  1BHH A;  1O4Q A;  5EEL A;  1MIL A;  1RJA A;  2JYQ A;  3GXX A;  1XA6 A;  1CSZ A;  2HDV A;  1R1Q A;  4XZ0 A;  3UYO A;  3IMD A;  2CI8 A;  1YVH A;  1OO4 A;  2EO3 A;  1ZFP E;  2ETZ A;  2HCK A;  1JWO A;  4XZ1 A;  2RSY A;  2K79 B;  2DCR A;  3ZNI A;  1I3Z A;  1O43 A;  3CD3 A;  1AYB A;  3VRQ A;  3VRZ A;  3IN8 A;  5DC0 B;  1RQQ C;  2AUG A;  3TL0 A;  1JYR A;  2Y1M A;  2LQN A;  3US4 A;  2K7A B;  2CBL A;  1LCJ A;  1H9O A;  2IZV A;  2PTK A;  2B3O A;  2LQW A;  3VRP A;  2DLY A;  4LUD A;  3MXY A;  4E68 A;  1A1A A;  1M27 A;  3CWG A;  4JGH A;  1LCK A;  1X0N A;  3VS4 A;  3VRN A;  2SHP A;  1LUN A;  2MC1 A;  1AOU F;  3CBL A;  4K11 A;  3N8M A;  1OPL A;  3PFV A;  5EHR A;  4GWF A;  1OO3 A;  4FL3 A;  5BO4 A;  4LUE A;  2HMH A;  1A1C A;  4L1B B;  3BUX B;  1SPR A;  1O4H A;  3BUN B;  3VS2 A;  1FHS A;  2FCI A;  3VS5 A;  3GQI B;  1BF5 A;  1AYC A;  1KC2 A;  2C0T A;  1O42 A;  2HUW A;  3IMJ A;  3VRY A;  5EG3 B;  2CR4 A;  1A09 A;  2FO0 A;  4K2R A;  1BMB A;  3N7Y A;  3BKB A;  4JE4 A;  1O4N A;  5HKZ A;  1HCS B;  1D4T A;  1O48 A;  4X6S A;  3BUW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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