5EELA

Grb7 sh2 with bicyclic peptide inhibitor
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
104
structure length
104
Chain Sequence
HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 7
molecule tags Signaling protein/peptide
source organism Homo sapiens
total genus 26
structure length 104
sequence length 104
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2015-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5eelA00
1MW4A 1X27A 4TZIA 2EYYA 1R1SA 3VS1A 4P9ZA 1AYDA 1G83A 4LUDA 2ETZA 3GXWA 2HDXA 1X6CA 1SPSA 2FCIA 5EHRA 2PLEA 4JE4A 3PQZA 2IUIA 2GSBA 1QCFA 1A1AA 1BMBA 3PSJA 1KSWA 5EEQA 3HIZB 4OHEA 2HDVA 4K11A 5EHPA 2B3OA 1BHHB 2LCTA 3N7YA 2LNWA 1BLKA 1O4DA 1Z3KA 1O44A 4NWGA 3IN8A 4A4BA 1O45A 3VRYA 5IBMA 1R1QA 4GWFA 1AYAA 1SHAA 3IN7A 4FL2A 3S9KA 4OHHA 1BLJA 1NRVA 1D4TA 1O4OA 4GPLB 3US4A 2JYQA 3VS4A 2KK6A 1OO3A 3T04A 2DLYA 3QWYA 1RQQC 1O4QA 5J3XA 1A09A 2EKXA 1LKLA 1LCJA 3UYOA 5HKYA 4OHIA 3HHMB 3VS0A 2MQIA 3N8MA 3OV1A 1JWOA 3VRZA 1O43A 1ZFPE 5DC9A 1MILA 2PTKA 3PFVA 5BO4A 1O4CA 4F59A 1A1CA 2EL8A 3VS7A 2LNXA 1FYRA 2RVFA 3ZNIA 2FO0A 1AB2A 2H5KA 5CDWA 3N84A 4EIHA 1IS0A 3BUWB 1FU6A 3VS2A 4DGPA 1A81A 1UURA 4GL9E 3VRNA 1Y57A 2C0TA 2EYZA 1BFIA 1CSYA 1AYCA 2HUWA 1H9OA 2BBUA 4FBNA 5HKZA 5D0JA 1P13A 3S8LA 4EY0A 1O42A 1LUKA 1O4LA 2HCKA 1O4BA 2MRJA 1CJ1A 3TKZA 2YU7A 4H34A 2CR4A 2PNAA 3OP0A 2MRKA 1LUIA 5AXIA 3MXCA 4K45A 1O4MA 2RORA 1O4PA 3C7IA 1O4HA 4K44A 3M7FA 5DC0B 2XP1A 1NZLA 3OB1B 1OO4A 3VGOA 1KC2A 2LQNA 4OHLA 1XA6A 4M4ZA 2DLZA 4F5AA 3GQIB 1PICA 1GRIA 1O4GA 1D4WA 1BHFA 4OHDA 2C0IA 2EYVA 3K2MA 1I3ZA 3CBLA 1O4FA 4A4CA 2QMSA 4L1BB 3QWXX 4FL3A 5EG3B 2DM0A 3VROA 1F1WA 3VRQA 1CWDL 1JYUA 3VS5A 3OVEA 1B47A 4U1PA 3BKBA 1LUMA 4P9VA 2H8HA 4NWFA 2IUGA 1O46A 2RMXA 2AUGA 1AYBA 2IZVA 2RSYA 1BF5A 4F5BA 3UF4A 2AOAA 4QSYA 1FBZA 2K79B 3IMDA 1GHUA 5HKWA 3VRRA 2L4KA 1TCEA 3PSKA 2AOBA 1O4IA 1O48A 1JYRA 3PLFB 3BUXB 3GXXA 2EOBA 3VRPA 1HCSB 1SHBA 1HCTB 3CD3A 3KFJA 3WA4A 1SPRA 1RPYA 2SHPA 5KAZA 3MXYA 4XZ1A 1A07A 1AD5A 4DGXA 1O41A 1O4JA 4K2RA 2CI8A 2DCRA 1M27A 3BUNB 3EAZA 1QG1E 1BKLA 4U17A 4E93A 1X0NA 2MK2A 1KA7A 1AOTF 1M61A 1SHDA 2CIAA 2DVJA 1Y1UA 1OPKA 1OPLA 2EO3A 2Y1MA 2H46E 2PLDA 4WWQA 2CBLA 2L6KA 1A08A 1JYQA 1O4AA 4LUEA 1KA6A 1JU5A 3EACA 1BHHA 1FMKA 1LUNA 3HCKA 2IUHA 3OB2B 2CS0A 1K9AA 5I6VA 3S8NA 1O49A 5DF6A 1F2FA 1FU5A 2LQWA 1CSZA 2YSXA 3IMJA 3VS3A 1NZVA 2VIFA 1CWEA 4XZ0A 2K7AB 1D1ZA 1UUSA 3PJPA 1TZEE 1AOUF 3BUMB 3MAZA 3S8OA 2SRCA 1FBVA 4X6SA 1BG1A 2Y3AB 1LCKA 4ROJA 1O4RA 1A1BA 2CRHA 5DC4A 1BM2A 2Y1NA 2PNBA 5GJHA 1A1EA 2ABLA 1O47A 3CXLA 3TL0A 1O4NA 1RJAA 2EU0A 1WQUA 3CWGA 2HMHA 1O4EA 3NHNA 2GE9A 2DX0A 1QADA 3PS5A 5GJIA 2EO6A 1O4KA 1FHSA 1YVLA 2OQ1A 4JEGA 2C0OA 5AULA 5EELA 1LKKA 1YVHA 1BFJA 2MC1A 4D8KA 1SKJA 4H1OA 4JGHA 2CI9A 2KNOA 3BUOB 2L3TA 2C9WA 1IJRA 1R1PA 1BKMA 2ECDA 5IBSA 4E68A 3VS6A 2OZOA
chains in the Genus database with same CATH superfamily
1MW4A 1X27A 4TZIA 2EYYA 1R1SA 3VS1A 4P9ZA 1AYDA 1G83A 4LUDA 2ETZA 3GXWA 2HDXA 1X6CA 1SPSA 2FCIA 5EHRA 2PLEA 4JE4A 3PQZA 2IUIA 2GSBA 1QCFA 1A1AA 1BMBA 3PSJA 1KSWA 5EEQA 3HIZB 4OHEA 2HDVA 4K11A 5EHPA 2B3OA 1BHHB 2LCTA 3N7YA 2LNWA 1BLKA 1O4DA 1Z3KA 1O44A 4NWGA 3IN8A 4A4BA 1O45A 3VRYA 5IBMA 1R1QA 4GWFA 1AYAA 1SHAA 3IN7A 4FL2A 3S9KA 4OHHA 1BLJA 1NRVA 1D4TA 1O4OA 4GPLB 3US4A 2JYQA 3VS4A 2KK6A 1OO3A 3T04A 2DLYA 3QWYA 1RQQC 1O4QA 5J3XA 1A09A 2EKXA 1LKLA 1LCJA 3UYOA 5HKYA 4OHIA 3HHMB 3VS0A 2MQIA 3N8MA 3OV1A 1JWOA 3VRZA 1O43A 1ZFPE 5DC9A 1MILA 2PTKA 3PFVA 5BO4A 1O4CA 4F59A 1A1CA 2EL8A 3K2TA 3VS7A 2LNXA 1FYRA 2RVFA 3ZNIA 2FO0A 1AB2A 2H5KA 5CDWA 3LYVA 3N84A 4EIHA 1IS0A 3BUWB 1FU6A 3VS2A 4DGPA 1A81A 1UURA 4GL9E 3VRNA 1Y57A 2C0TA 2EYZA 1BFIA 1CSYA 1AYCA 2HUWA 1H9OA 2BBUA 4FBNA 5HKZA 5D0JA 1P13A 3S8LA 4EY0A 1O42A 1LUKA 1O4LA 2HCKA 1O4BA 2MRJA 1CJ1A 3TKZA 2YU7A 4H34A 2CR4A 2PNAA 3OP0A 2MRKA 1LUIA 5AXIA 3MXCA 4K45A 1O4MA 2RORA 1O4PA 3C7IA 1O4HA 4K44A 3M7FA 5DC0B 2XP1A 1NZLA 3OB1B 1OO4A 3VGOA 1KC2A 2LQNA 4OHLA 1XA6A 4M4ZA 2DLZA 4F5AA 3GQIB 1PICA 1GRIA 1O4GA 1D4WA 1BHFA 4OHDA 2C0IA 2EYVA 3K2MA 1I3ZA 3CBLA 1O4FA 4A4CA 2QMSA 4L1BB 3QWXX 4FL3A 5EG3B 2DM0A 3VROA 1F1WA 3VRQA 1CWDL 1JYUA 3VS5A 3OVEA 1B47A 2KGYA 3BKBA 1LUMA 4U1PA 4P9VA 2H8HA 4NWFA 2IUGA 1O46A 2RMXA 2AUGA 1AYBA 2IZVA 2RSYA 1BF5A 4F5BA 3UF4A 2AOAA 4QSYA 1FBZA 2K79B 3IMDA 1GHUA 5HKWA 3VRRA 2L4KA 1TCEA 3PSKA 2AOBA 1O4IA 1O48A 1JYRA 3PLFB 3BUXB 3GXXA 2EOBA 3VRPA 1HCSB 1SHBA 1HCTB 3CD3A 3KFJA 3WA4A 1SPRA 1RPYA 2SHPA 5KAZA 3MXYA 4XZ1A 1A07A 1AD5A 4DGXA 1O41A 1O4JA 4K2RA 2CI8A 2DCRA 1M27A 3BUNB 3EAZA 1QG1E 1BKLA 4U17A 4E93A 1X0NA 2MK2A 1KA7A 1AOTF 1M61A 1SHDA 2CIAA 2DVJA 1Y1UA 1OPKA 1OPLA 2EO3A 2Y1MA 2H46E 2PLDA 4WWQA 2CBLA 2L6KA 1A08A 1JYQA 1O4AA 4LUEA 1KA6A 1JU5A 3EACA 1BHHA 1FMKA 1LUNA 3HCKA 2IUHA 3OB2B 2CS0A 1K9AA 5I6VA 3S8NA 1O49A 5DF6A 1F2FA 1FU5A 2LQWA 1CSZA 2YSXA 3IMJA 3VS3A 1NZVA 2VIFA 1CWEA 4XZ0A 2K7AB 1D1ZA 1UUSA 3PJPA 1TZEE 1AOUF 3BUMB 3MAZA 3S8OA 2SRCA 1FBVA 4X6SA 1BG1A 2Y3AB 1LCKA 4ROJA 1O4RA 2LRAA 1A1BA 2CRHA 5DC4A 1BM2A 2Y1NA 2PNBA 5GJHA 1A1EA 2ABLA 1O47A 3CXLA 3TL0A 1O4NA 1RJAA 2EU0A 1WQUA 3CWGA 2HMHA 1O4EA 3NHNA 2GE9A 2DX0A 1QADA 3PS5A 5GJIA 2EO6A 1O4KA 1FHSA 1YVLA 2OQ1A 4JEGA 2C0OA 5AULA 5EELA 1LKKA 1YVHA 1BFJA 2MC1A 4D8KA 1SKJA 4H1OA 4JGHA 2CI9A 2KNOA 3BUOB 2L3TA 2C9WA 1IJRA 1R1PA 1BKMA 2ECDA 5IBSA 4E68A 3VS6A 2OZOA
chains in the Genus database with same CATH topology
1MW4A 1X27A 4TZIA 2EYYA 1R1SA 3VS1A 4P9ZA 1AYDA 1G83A 4LUDA 2ETZA 3GXWA 2HDXA 1X6CA 1SPSA 2FCIA 5EHRA 2PLEA 4JE4A 3PQZA 2IUIA 2GSBA 1QCFA 1A1AA 1BMBA 3PSJA 1KSWA 5EEQA 3HIZB 4OHEA 2HDVA 4K11A 5EHPA 2B3OA 1BHHB 2LCTA 3N7YA 2LNWA 1BLKA 1O4DA 1Z3KA 1O44A 4NWGA 3IN8A 4A4BA 1O45A 3VRYA 5IBMA 1R1QA 4GWFA 1AYAA 1SHAA 3IN7A 4FL2A 3S9KA 4OHHA 1BLJA 1NRVA 1D4TA 1O4OA 4GPLB 3US4A 2JYQA 3VS4A 2KK6A 1OO3A 3T04A 2DLYA 3QWYA 1RQQC 1O4QA 5J3XA 1A09A 2EKXA 1LKLA 1LCJA 3UYOA 5HKYA 4OHIA 3HHMB 3VS0A 2MQIA 3N8MA 3OV1A 1JWOA 3VRZA 1O43A 1ZFPE 5DC9A 1MILA 2PTKA 3PFVA 5BO4A 1O4CA 4F59A 1A1CA 2EL8A 3VS7A 2LNXA 1FYRA 2RVFA 3ZNIA 2FO0A 1AB2A 2H5KA 5CDWA 3N84A 4EIHA 1IS0A 3BUWB 1FU6A 3VS2A 4DGPA 1A81A 1UURA 4GL9E 3VRNA 1Y57A 2C0TA 2EYZA 1BFIA 1CSYA 1AYCA 2HUWA 1H9OA 2BBUA 4FBNA 5HKZA 5D0JA 1P13A 3S8LA 4EY0A 1O42A 1LUKA 1O4LA 2HCKA 1O4BA 2MRJA 1CJ1A 3TKZA 2YU7A 4H34A 2CR4A 2PNAA 3OP0A 2MRKA 1LUIA 5AXIA 3MXCA 4K45A 1O4MA 2RORA 1O4PA 3C7IA 1O4HA 4K44A 3M7FA 5DC0B 2XP1A 1NZLA 3OB1B 1OO4A 3VGOA 1KC2A 2LQNA 4OHLA 1XA6A 4M4ZA 2DLZA 4F5AA 3GQIB 1PICA 1GRIA 1O4GA 1D4WA 1BHFA 4OHDA 2C0IA 2EYVA 3K2MA 1I3ZA 3CBLA 1O4FA 4A4CA 2QMSA 4L1BB 3QWXX 4FL3A 5EG3B 2DM0A 3VROA 1F1WA 3VRQA 1CWDL 1JYUA 3VS5A 3OVEA 1B47A 4U1PA 3BKBA 1LUMA 4P9VA 2H8HA 4NWFA 2IUGA 1O46A 2RMXA 2AUGA 1AYBA 2IZVA 2RSYA 1BF5A 4F5BA 3UF4A 2AOAA 4QSYA 1FBZA 2K79B 3IMDA 1GHUA 5HKWA 3VRRA 2L4KA 1TCEA 3PSKA 2AOBA 1O4IA 1O48A 1JYRA 3PLFB 3BUXB 3GXXA 2EOBA 3VRPA 1HCSB 1SHBA 1HCTB 3CD3A 3KFJA 3WA4A 1SPRA 1RPYA 2SHPA 5KAZA 3MXYA 4XZ1A 1A07A 1AD5A 4DGXA 1O41A 1O4JA 4K2RA 2CI8A 2DCRA 1M27A 3BUNB 3EAZA 1QG1E 1BKLA 4U17A 4E93A 1X0NA 2MK2A 1KA7A 1AOTF 1M61A 1SHDA 2CIAA 2DVJA 1Y1UA 1OPKA 1OPLA 2EO3A 2Y1MA 2H46E 2PLDA 4WWQA 2CBLA 2L6KA 1A08A 1JYQA 1O4AA 4LUEA 1KA6A 1JU5A 3EACA 1BHHA 1FMKA 1LUNA 3HCKA 2IUHA 3OB2B 2CS0A 1K9AA 5I6VA 3S8NA 1O49A 5DF6A 1F2FA 1FU5A 2LQWA 1CSZA 2YSXA 3IMJA 3VS3A 1NZVA 2VIFA 1CWEA 4XZ0A 2K7AB 1D1ZA 1UUSA 3PJPA 1TZEE 1AOUF 3BUMB 3MAZA 3S8OA 2SRCA 1FBVA 4X6SA 1BG1A 2Y3AB 1LCKA 4ROJA 1O4RA 1A1BA 2CRHA 5DC4A 1BM2A 2Y1NA 2PNBA 5GJHA 1A1EA 2ABLA 1O47A 3CXLA 3TL0A 1O4NA 1RJAA 2EU0A 1WQUA 3CWGA 2HMHA 1O4EA 3NHNA 2GE9A 2DX0A 1QADA 3PS5A 5GJIA 2EO6A 1O4KA 1FHSA 1YVLA 2OQ1A 4JEGA 2C0OA 5AULA 5EELA 1LKKA 1YVHA 1BFJA 2MC1A 4D8KA 1SKJA 4H1OA 4JGHA 2CI9A 2KNOA 3BUOB 2L3TA 2C9WA 1IJRA 1R1PA 1BKMA 2ECDA 5IBSA 4E68A 3VS6A 2OZOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MW4 A;  1X27 A;  4TZI A;  2EYY A;  1R1S A;  3VS1 A;  4P9Z A;  1AYD A;  1G83 A;  4LUD A;  2ETZ A;  3GXW A;  2HDX A;  1X6C A;  1SPS A;  2FCI A;  5EHR A;  2PLE A;  4JE4 A;  3PQZ A;  2IUI A;  2GSB A;  1QCF A;  1A1A A;  1BMB A;  3PSJ A;  1KSW A;  5EEQ A;  3HIZ B;  4OHE A;  2HDV A;  4K11 A;  5EHP A;  2B3O A;  1BHH B;  2LCT A;  3N7Y A;  2LNW A;  1BLK A;  1O4D A;  1Z3K A;  1O44 A;  4NWG A;  3IN8 A;  4A4B A;  1O45 A;  3VRY A;  5IBM A;  1R1Q A;  4GWF A;  1AYA A;  1SHA A;  3IN7 A;  4FL2 A;  3S9K A;  4OHH A;  1BLJ A;  1NRV A;  1D4T A;  1O4O A;  4GPL B;  3US4 A;  2JYQ A;  3VS4 A;  2KK6 A;  1OO3 A;  3T04 A;  2DLY A;  3QWY A;  1RQQ C;  1O4Q A;  5J3X A;  1A09 A;  2EKX A;  1LKL A;  1LCJ A;  3UYO A;  5HKY A;  4OHI A;  3HHM B;  3VS0 A;  2MQI A;  3N8M A;  3OV1 A;  1JWO A;  3VRZ A;  1O43 A;  1ZFP E;  5DC9 A;  1MIL A;  2PTK A;  3PFV A;  5BO4 A;  1O4C A;  4F59 A;  1A1C A;  2EL8 A;  3VS7 A;  2LNX A;  1FYR A;  2RVF A;  3ZNI A;  2FO0 A;  1AB2 A;  2H5K A;  5CDW A;  3N84 A;  4EIH A;  1IS0 A;  3BUW B;  1FU6 A;  3VS2 A;  4DGP A;  1A81 A;  1UUR A;  4GL9 E;  3VRN A;  1Y57 A;  2C0T A;  2EYZ A;  1BFI A;  1CSY A;  1AYC A;  2HUW A;  1H9O A;  2BBU A;  4FBN A;  5HKZ A;  5D0J A;  1P13 A;  3S8L A;  4EY0 A;  1O42 A;  1LUK A;  1O4L A;  2HCK A;  1O4B A;  2MRJ A;  1CJ1 A;  3TKZ A;  2YU7 A;  4H34 A;  2CR4 A;  2PNA A;  3OP0 A;  2MRK A;  1LUI A;  5AXI A;  3MXC A;  4K45 A;  1O4M A;  2ROR A;  1O4P A;  3C7I A;  1O4H A;  4K44 A;  3M7F A;  5DC0 B;  2XP1 A;  1NZL A;  3OB1 B;  1OO4 A;  3VGO A;  1KC2 A;  2LQN A;  4OHL A;  1XA6 A;  4M4Z A;  2DLZ A;  4F5A A;  3GQI B;  1PIC A;  1GRI A;  1O4G A;  1D4W A;  1BHF A;  4OHD A;  2C0I A;  2EYV A;  3K2M A;  1I3Z A;  3CBL A;  1O4F A;  4A4C A;  2QMS A;  4L1B B;  3QWX X;  4FL3 A;  5EG3 B;  2DM0 A;  3VRO A;  1F1W A;  3VRQ A;  1CWD L;  1JYU A;  3VS5 A;  3OVE A;  1B47 A;  4U1P A;  3BKB A;  1LUM A;  4P9V A;  2H8H A;  4NWF A;  2IUG A;  1O46 A;  2RMX A;  2AUG A;  1AYB A;  2IZV A;  2RSY A;  1BF5 A;  4F5B A;  3UF4 A;  2AOA A;  4QSY A;  1FBZ A;  2K79 B;  3IMD A;  1GHU A;  5HKW A;  3VRR A;  2L4K A;  1TCE A;  3PSK A;  2AOB A;  1O4I A;  1O48 A;  1JYR A;  3PLF B;  3BUX B;  3GXX A;  2EOB A;  3VRP A;  1HCS B;  1SHB A;  1HCT B;  3CD3 A;  3KFJ A;  3WA4 A;  1SPR A;  1RPY A;  2SHP A;  5KAZ A;  3MXY A;  4XZ1 A;  1A07 A;  1AD5 A;  4DGX A;  1O41 A;  1O4J A;  4K2R A;  2CI8 A;  2DCR A;  1M27 A;  3BUN B;  3EAZ A;  1QG1 E;  1BKL A;  4U17 A;  4E93 A;  1X0N A;  2MK2 A;  1KA7 A;  1AOT F;  1M61 A;  1SHD A;  2CIA A;  2DVJ A;  1Y1U A;  1OPK A;  1OPL A;  2EO3 A;  2Y1M A;  2H46 E;  2PLD A;  4WWQ A;  2CBL A;  2L6K A;  1A08 A;  1JYQ A;  1O4A A;  4LUE A;  1KA6 A;  1JU5 A;  3EAC A;  1BHH A;  1FMK A;  1LUN A;  3HCK A;  2IUH A;  3OB2 B;  2CS0 A;  1K9A A;  5I6V A;  3S8N A;  1O49 A;  5DF6 A;  1F2F A;  1FU5 A;  2LQW A;  1CSZ A;  2YSX A;  3IMJ A;  3VS3 A;  1NZV A;  2VIF A;  1CWE A;  4XZ0 A;  2K7A B;  1D1Z A;  1UUS A;  3PJP A;  1TZE E;  1AOU F;  3BUM B;  3MAZ A;  3S8O A;  2SRC A;  1FBV A;  4X6S A;  1BG1 A;  2Y3A B;  1LCK A;  4ROJ A;  1O4R A;  1A1B A;  2CRH A;  5DC4 A;  1BM2 A;  2Y1N A;  2PNB A;  5GJH A;  1A1E A;  2ABL A;  1O47 A;  3CXL A;  3TL0 A;  1O4N A;  1RJA A;  2EU0 A;  1WQU A;  3CWG A;  2HMH A;  1O4E A;  3NHN A;  2GE9 A;  2DX0 A;  1QAD A;  3PS5 A;  5GJI A;  2EO6 A;  1O4K A;  1FHS A;  1YVL A;  2OQ1 A;  4JEG A;  2C0O A;  5AUL A;  5EEL A;  1LKK A;  1YVH A;  1BFJ A;  2MC1 A;  4D8K A;  1SKJ A;  4H1O A;  4JGH A;  2CI9 A;  2KNO A;  3BUO B;  2L3T A;  2C9W A;  1IJR A;  1R1P A;  1BKM A;  2ECD A;  5IBS A;  4E68 A;  3VS6 A;  2OZO A; 
#chains in the Genus database with same CATH topology
 1MW4 A;  1X27 A;  4TZI A;  2EYY A;  1R1S A;  3VS1 A;  4P9Z A;  1AYD A;  1G83 A;  4LUD A;  2ETZ A;  3GXW A;  2HDX A;  1X6C A;  1SPS A;  2FCI A;  5EHR A;  2PLE A;  4JE4 A;  3PQZ A;  2IUI A;  2GSB A;  1QCF A;  1A1A A;  1BMB A;  3PSJ A;  1KSW A;  5EEQ A;  3HIZ B;  4OHE A;  2HDV A;  4K11 A;  5EHP A;  2B3O A;  1BHH B;  2LCT A;  3N7Y A;  2LNW A;  1BLK A;  1O4D A;  1Z3K A;  1O44 A;  4NWG A;  3IN8 A;  4A4B A;  1O45 A;  3VRY A;  5IBM A;  1R1Q A;  4GWF A;  1AYA A;  1SHA A;  3IN7 A;  4FL2 A;  3S9K A;  4OHH A;  1BLJ A;  1NRV A;  1D4T A;  1O4O A;  4GPL B;  3US4 A;  2JYQ A;  3VS4 A;  2KK6 A;  1OO3 A;  3T04 A;  2DLY A;  3QWY A;  1RQQ C;  1O4Q A;  5J3X A;  1A09 A;  2EKX A;  1LKL A;  1LCJ A;  3UYO A;  5HKY A;  4OHI A;  3HHM B;  3VS0 A;  2MQI A;  3N8M A;  3OV1 A;  1JWO A;  3VRZ A;  1O43 A;  1ZFP E;  5DC9 A;  1MIL A;  2PTK A;  3PFV A;  5BO4 A;  1O4C A;  4F59 A;  1A1C A;  2EL8 A;  3K2T A;  3VS7 A;  2LNX A;  1FYR A;  2RVF A;  3ZNI A;  2FO0 A;  1AB2 A;  2H5K A;  5CDW A;  3LYV A;  3N84 A;  4EIH A;  1IS0 A;  3BUW B;  1FU6 A;  3VS2 A;  4DGP A;  1A81 A;  1UUR A;  4GL9 E;  3VRN A;  1Y57 A;  2C0T A;  2EYZ A;  1BFI A;  1CSY A;  1AYC A;  2HUW A;  1H9O A;  2BBU A;  4FBN A;  5HKZ A;  5D0J A;  1P13 A;  3S8L A;  4EY0 A;  1O42 A;  1LUK A;  1O4L A;  2HCK A;  1O4B A;  2MRJ A;  1CJ1 A;  3TKZ A;  2YU7 A;  4H34 A;  2CR4 A;  2PNA A;  3OP0 A;  2MRK A;  1LUI A;  5AXI A;  3MXC A;  4K45 A;  1O4M A;  2ROR A;  1O4P A;  3C7I A;  1O4H A;  4K44 A;  3M7F A;  5DC0 B;  2XP1 A;  1NZL A;  3OB1 B;  1OO4 A;  3VGO A;  1KC2 A;  2LQN A;  4OHL A;  1XA6 A;  4M4Z A;  2DLZ A;  4F5A A;  3GQI B;  1PIC A;  1GRI A;  1O4G A;  1D4W A;  1BHF A;  4OHD A;  2C0I A;  2EYV A;  3K2M A;  1I3Z A;  3CBL A;  1O4F A;  4A4C A;  2QMS A;  4L1B B;  3QWX X;  4FL3 A;  5EG3 B;  2DM0 A;  3VRO A;  1F1W A;  3VRQ A;  1CWD L;  1JYU A;  3VS5 A;  3OVE A;  1B47 A;  2KGY A;  3BKB A;  1LUM A;  4U1P A;  4P9V A;  2H8H A;  4NWF A;  2IUG A;  1O46 A;  2RMX A;  2AUG A;  1AYB A;  2IZV A;  2RSY A;  1BF5 A;  4F5B A;  3UF4 A;  2AOA A;  4QSY A;  1FBZ A;  2K79 B;  3IMD A;  1GHU A;  5HKW A;  3VRR A;  2L4K A;  1TCE A;  3PSK A;  2AOB A;  1O4I A;  1O48 A;  1JYR A;  3PLF B;  3BUX B;  3GXX A;  2EOB A;  3VRP A;  1HCS B;  1SHB A;  1HCT B;  3CD3 A;  3KFJ A;  3WA4 A;  1SPR A;  1RPY A;  2SHP A;  5KAZ A;  3MXY A;  4XZ1 A;  1A07 A;  1AD5 A;  4DGX A;  1O41 A;  1O4J A;  4K2R A;  2CI8 A;  2DCR A;  1M27 A;  3BUN B;  3EAZ A;  1QG1 E;  1BKL A;  4U17 A;  4E93 A;  1X0N A;  2MK2 A;  1KA7 A;  1AOT F;  1M61 A;  1SHD A;  2CIA A;  2DVJ A;  1Y1U A;  1OPK A;  1OPL A;  2EO3 A;  2Y1M A;  2H46 E;  2PLD A;  4WWQ A;  2CBL A;  2L6K A;  1A08 A;  1JYQ A;  1O4A A;  4LUE A;  1KA6 A;  1JU5 A;  3EAC A;  1BHH A;  1FMK A;  1LUN A;  3HCK A;  2IUH A;  3OB2 B;  2CS0 A;  1K9A A;  5I6V A;  3S8N A;  1O49 A;  5DF6 A;  1F2F A;  1FU5 A;  2LQW A;  1CSZ A;  2YSX A;  3IMJ A;  3VS3 A;  1NZV A;  2VIF A;  1CWE A;  4XZ0 A;  2K7A B;  1D1Z A;  1UUS A;  3PJP A;  1TZE E;  1AOU F;  3BUM B;  3MAZ A;  3S8O A;  2SRC A;  1FBV A;  4X6S A;  1BG1 A;  2Y3A B;  1LCK A;  4ROJ A;  1O4R A;  2LRA A;  1A1B A;  2CRH A;  5DC4 A;  1BM2 A;  2Y1N A;  2PNB A;  5GJH A;  1A1E A;  2ABL A;  1O47 A;  3CXL A;  3TL0 A;  1O4N A;  1RJA A;  2EU0 A;  1WQU A;  3CWG A;  2HMH A;  1O4E A;  3NHN A;  2GE9 A;  2DX0 A;  1QAD A;  3PS5 A;  5GJI A;  2EO6 A;  1O4K A;  1FHS A;  1YVL A;  2OQ1 A;  4JEG A;  2C0O A;  5AUL A;  5EEL A;  1LKK A;  1YVH A;  1BFJ A;  2MC1 A;  4D8K A;  1SKJ A;  4H1O A;  4JGH A;  2CI9 A;  2KNO A;  3BUO B;  2L3T A;  2C9W A;  1IJR A;  1R1P A;  1BKM A;  2ECD A;  5IBS A;  4E68 A;  3VS6 A;  2OZO A; 
#chains in the Genus database with same CATH homology
 1MW4 A;  1X27 A;  4TZI A;  2EYY A;  1R1S A;  3VS1 A;  4P9Z A;  1AYD A;  1G83 A;  4LUD A;  2ETZ A;  3GXW A;  2HDX A;  1X6C A;  1SPS A;  2FCI A;  5EHR A;  2PLE A;  4JE4 A;  3PQZ A;  2IUI A;  2GSB A;  1QCF A;  1A1A A;  1BMB A;  3PSJ A;  1KSW A;  5EEQ A;  3HIZ B;  4OHE A;  2HDV A;  4K11 A;  5EHP A;  2B3O A;  1BHH B;  2LCT A;  3N7Y A;  2LNW A;  1BLK A;  1O4D A;  1Z3K A;  1O44 A;  4NWG A;  3IN8 A;  4A4B A;  1O45 A;  3VRY A;  5IBM A;  1R1Q A;  4GWF A;  1AYA A;  1SHA A;  3IN7 A;  4FL2 A;  3S9K A;  4OHH A;  1BLJ A;  1NRV A;  1D4T A;  1O4O A;  4GPL B;  3US4 A;  2JYQ A;  3VS4 A;  2KK6 A;  1OO3 A;  3T04 A;  2DLY A;  3QWY A;  1RQQ C;  1O4Q A;  5J3X A;  1A09 A;  2EKX A;  1LKL A;  1LCJ A;  3UYO A;  5HKY A;  4OHI A;  3HHM B;  3VS0 A;  2MQI A;  3N8M A;  3OV1 A;  1JWO A;  3VRZ A;  1O43 A;  1ZFP E;  5DC9 A;  1MIL A;  2PTK A;  3PFV A;  5BO4 A;  1O4C A;  4F59 A;  1A1C A;  2EL8 A;  3VS7 A;  2LNX A;  1FYR A;  2RVF A;  3ZNI A;  2FO0 A;  1AB2 A;  2H5K A;  5CDW A;  3N84 A;  4EIH A;  1IS0 A;  3BUW B;  1FU6 A;  3VS2 A;  4DGP A;  1A81 A;  1UUR A;  4GL9 E;  3VRN A;  1Y57 A;  2C0T A;  2EYZ A;  1BFI A;  1CSY A;  1AYC A;  2HUW A;  1H9O A;  2BBU A;  4FBN A;  5HKZ A;  5D0J A;  1P13 A;  3S8L A;  4EY0 A;  1O42 A;  1LUK A;  1O4L A;  2HCK A;  1O4B A;  2MRJ A;  1CJ1 A;  3TKZ A;  2YU7 A;  4H34 A;  2CR4 A;  2PNA A;  3OP0 A;  2MRK A;  1LUI A;  5AXI A;  3MXC A;  4K45 A;  1O4M A;  2ROR A;  1O4P A;  3C7I A;  1O4H A;  4K44 A;  3M7F A;  5DC0 B;  2XP1 A;  1NZL A;  3OB1 B;  1OO4 A;  3VGO A;  1KC2 A;  2LQN A;  4OHL A;  1XA6 A;  4M4Z A;  2DLZ A;  4F5A A;  3GQI B;  1PIC A;  1GRI A;  1O4G A;  1D4W A;  1BHF A;  4OHD A;  2C0I A;  2EYV A;  3K2M A;  1I3Z A;  3CBL A;  1O4F A;  4A4C A;  2QMS A;  4L1B B;  3QWX X;  4FL3 A;  5EG3 B;  2DM0 A;  3VRO A;  1F1W A;  3VRQ A;  1CWD L;  1JYU A;  3VS5 A;  3OVE A;  1B47 A;  4U1P A;  3BKB A;  1LUM A;  4P9V A;  2H8H A;  4NWF A;  2IUG A;  1O46 A;  2RMX A;  2AUG A;  1AYB A;  2IZV A;  2RSY A;  1BF5 A;  4F5B A;  3UF4 A;  2AOA A;  4QSY A;  1FBZ A;  2K79 B;  3IMD A;  1GHU A;  5HKW A;  3VRR A;  2L4K A;  1TCE A;  3PSK A;  2AOB A;  1O4I A;  1O48 A;  1JYR A;  3PLF B;  3BUX B;  3GXX A;  2EOB A;  3VRP A;  1HCS B;  1SHB A;  1HCT B;  3CD3 A;  3KFJ A;  3WA4 A;  1SPR A;  1RPY A;  2SHP A;  5KAZ A;  3MXY A;  4XZ1 A;  1A07 A;  1AD5 A;  4DGX A;  1O41 A;  1O4J A;  4K2R A;  2CI8 A;  2DCR A;  1M27 A;  3BUN B;  3EAZ A;  1QG1 E;  1BKL A;  4U17 A;  4E93 A;  1X0N A;  2MK2 A;  1KA7 A;  1AOT F;  1M61 A;  1SHD A;  2CIA A;  2DVJ A;  1Y1U A;  1OPK A;  1OPL A;  2EO3 A;  2Y1M A;  2H46 E;  2PLD A;  4WWQ A;  2CBL A;  2L6K A;  1A08 A;  1JYQ A;  1O4A A;  4LUE A;  1KA6 A;  1JU5 A;  3EAC A;  1BHH A;  1FMK A;  1LUN A;  3HCK A;  2IUH A;  3OB2 B;  2CS0 A;  1K9A A;  5I6V A;  3S8N A;  1O49 A;  5DF6 A;  1F2F A;  1FU5 A;  2LQW A;  1CSZ A;  2YSX A;  3IMJ A;  3VS3 A;  1NZV A;  2VIF A;  1CWE A;  4XZ0 A;  2K7A B;  1D1Z A;  1UUS A;  3PJP A;  1TZE E;  1AOU F;  3BUM B;  3MAZ A;  3S8O A;  2SRC A;  1FBV A;  4X6S A;  1BG1 A;  2Y3A B;  1LCK A;  4ROJ A;  1O4R A;  1A1B A;  2CRH A;  5DC4 A;  1BM2 A;  2Y1N A;  2PNB A;  5GJH A;  1A1E A;  2ABL A;  1O47 A;  3CXL A;  3TL0 A;  1O4N A;  1RJA A;  2EU0 A;  1WQU A;  3CWG A;  2HMH A;  1O4E A;  3NHN A;  2GE9 A;  2DX0 A;  1QAD A;  3PS5 A;  5GJI A;  2EO6 A;  1O4K A;  1FHS A;  1YVL A;  2OQ1 A;  4JEG A;  2C0O A;  5AUL A;  5EEL A;  1LKK A;  1YVH A;  1BFJ A;  2MC1 A;  4D8K A;  1SKJ A;  4H1O A;  4JGH A;  2CI9 A;  2KNO A;  3BUO B;  2L3T A;  2C9W A;  1IJR A;  1R1P A;  1BKM A;  2ECD A;  5IBS A;  4E68 A;  3VS6 A;  2OZO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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