1FBZA

Structure-based design of a novel, osteoclast-selective, nonpeptide src sh2 inhibitor with in vivo anti-resorptive activity
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
104
structure length
104
Chain Sequence
b'EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFCLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK
publication title Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 20
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2000-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1fbzA00
1KC2A 3HIZB 5AXIA 4LUDA 3NHNA 1BG1A 1YVHA 1QADA 2ABLA 1KSWA 5DF6A 4OHHA 2K7AB 1AYAA 3QWYA 3CXLA 1JYRA 4DGXA 2IZVA 2H5KA 1D4TA 2LCTA 1LKLA 1D1ZA 4FL2A 5AULA 1FMKA 1BM2A 1ZFPE 2EYZA 3PSJA 1AYBA 3OP0A 1A1BA 1JU5A 4GWFA 1TCEA 2FCIA 1SHBA 5CDWA 5KAZA 1O41A 3VRPA 1M61A 1H9OA 4GL9E 1K9AA 1SPRA 1MILA 1WQUA 1O4PA 3TL0A 2YU7A 2SRCA 3CWGA 1LKKA 1B47A 4F59A 3MXCA 3WA4A 1O43A 1HCTB 1HCSB 3M7FA 1R1SA 1X6CA 4U17A 5EEQA 4OHIA 4LUEA 1BLKA 1O44A 1O4GA 2RORA 4K44A 3N7YA 2LQNA 2EKXA 1A81A 4FBNA 3VS5A 2PNBA 3N8MA 4F5BA 2AOBA 2EU0A 1O45A 4ROJA 2GSBA 2CRHA 4EY0A 2AUGA 2PTKA 2C0OA 3K2MA 2CIAA 5EHRA 3VGOA 1CWDL 3GXXA 1OO3A 1FYRA 1AB2A 2LNXA 3VS1A 2DCRA 5HKWA 2ECDA 3TKZA 1NZVA 1AOUF 2KNOA 3S8LA 4EIHA 3OB2B 1BKMA 1CJ1A 2L6KA 1BMBA 2EO3A 4M4ZA 1SHAA 3IN7A 3IMJA 1OPLA 3CBLA 2DX0A 4WWQA 1O46A 2FO0A 5HKYA 3N84A 4K45A 2CBLA 2AOAA 1RPYA 4L1BB 3VS6A 1O4LA 1O4MA 2MRKA 4NWGA 5EELA 3VS0A 5J3XA 2OZOA 4OHDA 1Z3KA 3PLFB 5IBSA 2DM0A 3IMDA 5HKZA 3OB1B 3OVEA 5D0JA 2IUHA 4X6SA 2EYVA 2DLZA 2H8HA 4OHLA 1LUNA 2IUIA 3BUNB 2MRJA 1QCFA 1O4BA 1A07A 3US4A 2HCKA 2C9WA 1RQQC 2JYQA 4K11A 1BLJA 4XZ0A 2Y1MA 4K2RA 1X0NA 3EACA 2BBUA 2MC1A 1FU6A 1KA6A 1O4FA 4E93A 3EAZA 3PSKA 4TZIA 1OPKA 4D8KA 1O4JA 4XZ1A 2RSYA 3PFVA 4H34A 2HDVA 2L4KA 3VS3A 3C7IA 4JGHA 3CD3A 1SKJA 1NRVA 1AYCA 1O42A 5DC4A 1M27A 1I3ZA 5I6VA 1AYDA 1R1QA 1LUMA 1LCKA 1BF5A 2IUGA 2QMSA 2HDXA 1IJRA 1RJAA 1FU5A 2L3TA 5GJHA 4H1OA 4DGPA 1O4OA 3S9KA 2RVFA 1LCJA 3GXWA 5IBMA 1JYQA 2Y3AB 1A1EA 1O4NA 1UURA 2SHPA 3QWXX 5EHPA 3BUWB 1BKLA 1Y57A 1D4WA 1P13A 1KA7A 1A09A 1MW4A 4P9VA 1O48A 4OHEA 4A4CA 3UF4A 1BHHB 1O47A 3VRRA 2CI8A 1GRIA 4JEGA 1FBVA 3UYOA 4U1PA 3BUXB 2H46E 2YSXA 3BUOB 2OQ1A 2LQWA 2LNWA 3VS4A 4F5AA 1O4AA 3S8NA 1O4CA 1AD5A 3VROA 2EO6A 3GQIB 3PJPA 1SHDA 2K79B 4GPLB 1X27A 1GHUA 1YVLA 1O4IA 5EG3B 3HCKA 1OO4A 1BFJA 3VRQA 1F2FA 5GJIA 1BFIA 3IN8A 1R1PA 1CSYA 2C0IA 1BHFA 1CWEA 3KFJA 3HHMB 3BKBA 1F1WA 1O49A 2B3OA 2KK6A 1A1CA 3ZNIA 2PLEA 2C0TA 1O4DA 1G83A 2CI9A 2DVJA 3MXYA 2HMHA 4A4BA 1IS0A 1A1AA 1O4HA 1Y1UA 1NZLA 1PICA 2RMXA 3S8OA 1BHHA 1LUIA 2CR4A 2GE9A 1O4KA 1JWOA 2CS0A 1XA6A 5BO4A 3VRNA 2Y1NA 3OV1A 2EOBA 2MQIA 1QG1E 2EL8A 2HUWA 2DLYA 4JE4A 3VS7A 1A08A 1LUKA 4FL3A 3VRZA 2ETZA 3VS2A 1SPSA 3BUMB 1O4EA 2PNAA 2EYYA 4NWFA 1FBZA 1UUSA 4E68A 1O4QA 5DC9A 4P9ZA 1O4RA 3PQZA 1FHSA 3T04A 1TZEE 1CSZA 2VIFA 4QSYA 1AOTF 3PS5A 3MAZA 3VRYA 2PLDA 2XP1A 5DC0B 2MK2A 1JYUA
chains in the Genus database with same CATH superfamily
1KC2A 3HIZB 5AXIA 4LUDA 3NHNA 1BG1A 1YVHA 1QADA 2ABLA 1KSWA 5DF6A 4OHHA 2K7AB 1AYAA 3QWYA 3CXLA 1JYRA 4DGXA 2IZVA 2H5KA 1D4TA 2LCTA 1LKLA 1D1ZA 4FL2A 5AULA 1FMKA 1BM2A 1ZFPE 2EYZA 3PSJA 1AYBA 3OP0A 1A1BA 1JU5A 4GWFA 1TCEA 2FCIA 1SHBA 5CDWA 5KAZA 1O41A 3VRPA 1M61A 1H9OA 4GL9E 1K9AA 1SPRA 1MILA 1WQUA 1O4PA 3TL0A 2YU7A 2SRCA 3CWGA 1LKKA 1B47A 4F59A 3MXCA 3WA4A 1O43A 1HCTB 1HCSB 3M7FA 1R1SA 1X6CA 4U17A 5EEQA 4OHIA 4LUEA 1BLKA 1O44A 3LYVA 1O4GA 2RORA 4K44A 3N7YA 2LQNA 2EKXA 1A81A 4FBNA 3VS5A 2PNBA 3N8MA 4F5BA 2AOBA 2EU0A 2KGYA 1O45A 4ROJA 2GSBA 2CRHA 4EY0A 2AUGA 2PTKA 2C0OA 3K2MA 2CIAA 5EHRA 3VGOA 1CWDL 3GXXA 1OO3A 1FYRA 1AB2A 2LNXA 3VS1A 2DCRA 5HKWA 2ECDA 3TKZA 1NZVA 1AOUF 2KNOA 3S8LA 4EIHA 3OB2B 1BKMA 1CJ1A 2L6KA 1BMBA 2EO3A 4M4ZA 1SHAA 3IN7A 3IMJA 1OPLA 3CBLA 2DX0A 4WWQA 1O46A 2FO0A 5HKYA 3N84A 4K45A 2CBLA 2AOAA 1RPYA 4L1BB 3VS6A 1O4LA 1O4MA 2MRKA 4NWGA 5EELA 3VS0A 5J3XA 2OZOA 4OHDA 1Z3KA 3PLFB 5IBSA 2DM0A 3IMDA 5HKZA 3OB1B 3OVEA 5D0JA 2IUHA 4X6SA 2EYVA 2DLZA 2H8HA 4OHLA 1LUNA 2IUIA 3BUNB 2MRJA 1QCFA 1O4BA 1A07A 3US4A 2HCKA 2C9WA 1RQQC 2JYQA 4K11A 1BLJA 4XZ0A 2Y1MA 4K2RA 1X0NA 3EACA 2BBUA 2MC1A 1FU6A 1KA6A 1O4FA 4E93A 3EAZA 3PSKA 4TZIA 1OPKA 4D8KA 1O4JA 4XZ1A 2RSYA 3PFVA 4H34A 2HDVA 2L4KA 3VS3A 3C7IA 4JGHA 3CD3A 1SKJA 1NRVA 1AYCA 1O42A 5DC4A 1M27A 1I3ZA 5I6VA 2LRAA 1AYDA 1R1QA 1LUMA 1LCKA 1BF5A 2IUGA 2QMSA 2HDXA 1IJRA 1RJAA 1FU5A 2L3TA 5GJHA 4H1OA 4DGPA 1O4OA 3S9KA 2RVFA 1LCJA 3GXWA 5IBMA 1JYQA 2Y3AB 1A1EA 1O4NA 1UURA 2SHPA 3QWXX 5EHPA 3BUWB 1BKLA 1Y57A 1D4WA 1P13A 1KA7A 1A09A 1MW4A 4P9VA 1O48A 4OHEA 4A4CA 3UF4A 1BHHB 1O47A 3VRRA 2CI8A 1GRIA 4JEGA 1FBVA 3UYOA 4U1PA 3BUXB 2H46E 2YSXA 3BUOB 2OQ1A 2LQWA 2LNWA 3VS4A 4F5AA 1O4AA 3S8NA 1O4CA 1AD5A 3VROA 2EO6A 3GQIB 3PJPA 1SHDA 2K79B 4GPLB 1X27A 1GHUA 1YVLA 3K2TA 1O4IA 5EG3B 3HCKA 1OO4A 1BFJA 3VRQA 1F2FA 5GJIA 1BFIA 3IN8A 1R1PA 1CSYA 2C0IA 1BHFA 1CWEA 3KFJA 3HHMB 3BKBA 1F1WA 1O49A 2B3OA 2KK6A 1A1CA 3ZNIA 2PLEA 2C0TA 1O4DA 1G83A 2CI9A 2DVJA 3MXYA 2HMHA 4A4BA 1IS0A 1A1AA 1O4HA 1Y1UA 1NZLA 1PICA 2RMXA 3S8OA 1BHHA 1LUIA 2CR4A 2GE9A 1O4KA 1JWOA 2CS0A 1XA6A 5BO4A 3VRNA 2Y1NA 3OV1A 2EOBA 2MQIA 1QG1E 2EL8A 2HUWA 2DLYA 4JE4A 3VS7A 1A08A 1LUKA 4FL3A 3VRZA 2ETZA 3VS2A 1SPSA 3BUMB 1O4EA 2PNAA 2EYYA 4NWFA 1FBZA 1UUSA 4E68A 1O4QA 5DC9A 4P9ZA 1O4RA 3PQZA 1FHSA 3T04A 1TZEE 1CSZA 2VIFA 4QSYA 1AOTF 3PS5A 3MAZA 3VRYA 2PLDA 2XP1A 5DC0B 2MK2A 1JYUA
chains in the Genus database with same CATH topology
1KC2A 3HIZB 5AXIA 4LUDA 3NHNA 1BG1A 1YVHA 1QADA 2ABLA 1KSWA 5DF6A 4OHHA 2K7AB 1AYAA 3QWYA 3CXLA 1JYRA 4DGXA 2IZVA 2H5KA 1D4TA 2LCTA 1LKLA 1D1ZA 4FL2A 5AULA 1FMKA 1BM2A 1ZFPE 2EYZA 3PSJA 1AYBA 3OP0A 1A1BA 1JU5A 4GWFA 1TCEA 2FCIA 1SHBA 5CDWA 5KAZA 1O41A 3VRPA 1M61A 1H9OA 4GL9E 1K9AA 1SPRA 1MILA 1WQUA 1O4PA 3TL0A 2YU7A 2SRCA 3CWGA 1LKKA 1B47A 4F59A 3MXCA 3WA4A 1O43A 1HCTB 1HCSB 3M7FA 1R1SA 1X6CA 4U17A 5EEQA 4OHIA 4LUEA 1BLKA 1O44A 1O4GA 2RORA 4K44A 3N7YA 2LQNA 2EKXA 1A81A 4FBNA 3VS5A 2PNBA 3N8MA 4F5BA 2AOBA 2EU0A 1O45A 4ROJA 2GSBA 2CRHA 4EY0A 2AUGA 2PTKA 2C0OA 3K2MA 2CIAA 5EHRA 3VGOA 1CWDL 3GXXA 1OO3A 1FYRA 1AB2A 2LNXA 3VS1A 2DCRA 5HKWA 2ECDA 3TKZA 1NZVA 1AOUF 2KNOA 3S8LA 4EIHA 3OB2B 1BKMA 1CJ1A 2L6KA 1BMBA 2EO3A 4M4ZA 1SHAA 3IN7A 3IMJA 1OPLA 3CBLA 2DX0A 4WWQA 1O46A 2FO0A 5HKYA 3N84A 4K45A 2CBLA 2AOAA 1RPYA 4L1BB 3VS6A 1O4LA 1O4MA 2MRKA 4NWGA 5EELA 3VS0A 5J3XA 2OZOA 4OHDA 1Z3KA 3PLFB 5IBSA 2DM0A 3IMDA 5HKZA 3OB1B 3OVEA 5D0JA 2IUHA 4X6SA 2EYVA 2DLZA 2H8HA 4OHLA 1LUNA 2IUIA 3BUNB 2MRJA 1QCFA 1O4BA 1A07A 3US4A 2HCKA 2C9WA 1RQQC 2JYQA 4K11A 1BLJA 4XZ0A 2Y1MA 4K2RA 1X0NA 3EACA 2BBUA 2MC1A 1FU6A 1KA6A 1O4FA 4E93A 3EAZA 3PSKA 4TZIA 1OPKA 4D8KA 1O4JA 4XZ1A 2RSYA 3PFVA 4H34A 2HDVA 2L4KA 3VS3A 3C7IA 4JGHA 3CD3A 1SKJA 1NRVA 1AYCA 1O42A 5DC4A 1M27A 1I3ZA 5I6VA 1AYDA 1R1QA 1LUMA 1LCKA 1BF5A 2IUGA 2QMSA 2HDXA 1IJRA 1RJAA 1FU5A 2L3TA 5GJHA 4H1OA 4DGPA 1O4OA 3S9KA 2RVFA 1LCJA 3GXWA 5IBMA 1JYQA 2Y3AB 1A1EA 1O4NA 1UURA 2SHPA 3QWXX 5EHPA 3BUWB 1BKLA 1Y57A 1D4WA 1P13A 1KA7A 1A09A 1MW4A 4P9VA 1O48A 4OHEA 4A4CA 3UF4A 1BHHB 1O47A 3VRRA 2CI8A 1GRIA 4JEGA 1FBVA 3UYOA 4U1PA 3BUXB 2H46E 2YSXA 3BUOB 2OQ1A 2LQWA 2LNWA 3VS4A 4F5AA 1O4AA 3S8NA 1O4CA 1AD5A 3VROA 2EO6A 3GQIB 3PJPA 1SHDA 2K79B 4GPLB 1X27A 1GHUA 1YVLA 1O4IA 5EG3B 3HCKA 1OO4A 1BFJA 3VRQA 1F2FA 5GJIA 1BFIA 3IN8A 1R1PA 1CSYA 2C0IA 1BHFA 1CWEA 3KFJA 3HHMB 3BKBA 1F1WA 1O49A 2B3OA 2KK6A 1A1CA 3ZNIA 2PLEA 2C0TA 1O4DA 1G83A 2CI9A 2DVJA 3MXYA 2HMHA 4A4BA 1IS0A 1A1AA 1O4HA 1Y1UA 1NZLA 1PICA 2RMXA 3S8OA 1BHHA 1LUIA 2CR4A 2GE9A 1O4KA 1JWOA 2CS0A 1XA6A 5BO4A 3VRNA 2Y1NA 3OV1A 2EOBA 2MQIA 1QG1E 2EL8A 2HUWA 2DLYA 4JE4A 3VS7A 1A08A 1LUKA 4FL3A 3VRZA 2ETZA 3VS2A 1SPSA 3BUMB 1O4EA 2PNAA 2EYYA 4NWFA 1FBZA 1UUSA 4E68A 1O4QA 5DC9A 4P9ZA 1O4RA 3PQZA 1FHSA 3T04A 1TZEE 1CSZA 2VIFA 4QSYA 1AOTF 3PS5A 3MAZA 3VRYA 2PLDA 2XP1A 5DC0B 2MK2A 1JYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KC2 A;  3HIZ B;  5AXI A;  4LUD A;  3NHN A;  1BG1 A;  1YVH A;  1QAD A;  2ABL A;  1KSW A;  5DF6 A;  4OHH A;  2K7A B;  1AYA A;  3QWY A;  3CXL A;  1JYR A;  4DGX A;  2IZV A;  2H5K A;  1D4T A;  2LCT A;  1LKL A;  1D1Z A;  4FL2 A;  5AUL A;  1FMK A;  1BM2 A;  1ZFP E;  2EYZ A;  3PSJ A;  1AYB A;  3OP0 A;  1A1B A;  1JU5 A;  4GWF A;  1TCE A;  2FCI A;  1SHB A;  5CDW A;  5KAZ A;  1O41 A;  3VRP A;  1M61 A;  1H9O A;  4GL9 E;  1K9A A;  1SPR A;  1MIL A;  1WQU A;  1O4P A;  3TL0 A;  2YU7 A;  2SRC A;  3CWG A;  1LKK A;  1B47 A;  4F59 A;  3MXC A;  3WA4 A;  1O43 A;  1HCT B;  1HCS B;  3M7F A;  1R1S A;  1X6C A;  4U17 A;  5EEQ A;  4OHI A;  4LUE A;  1BLK A;  1O44 A;  1O4G A;  2ROR A;  4K44 A;  3N7Y A;  2LQN A;  2EKX A;  1A81 A;  4FBN A;  3VS5 A;  2PNB A;  3N8M A;  4F5B A;  2AOB A;  2EU0 A;  1O45 A;  4ROJ A;  2GSB A;  2CRH A;  4EY0 A;  2AUG A;  2PTK A;  2C0O A;  3K2M A;  2CIA A;  5EHR A;  3VGO A;  1CWD L;  3GXX A;  1OO3 A;  1FYR A;  1AB2 A;  2LNX A;  3VS1 A;  2DCR A;  5HKW A;  2ECD A;  3TKZ A;  1NZV A;  1AOU F;  2KNO A;  3S8L A;  4EIH A;  3OB2 B;  1BKM A;  1CJ1 A;  2L6K A;  1BMB A;  2EO3 A;  4M4Z A;  1SHA A;  3IN7 A;  3IMJ A;  1OPL A;  3CBL A;  2DX0 A;  4WWQ A;  1O46 A;  2FO0 A;  5HKY A;  3N84 A;  4K45 A;  2CBL A;  2AOA A;  1RPY A;  4L1B B;  3VS6 A;  1O4L A;  1O4M A;  2MRK A;  4NWG A;  5EEL A;  3VS0 A;  5J3X A;  2OZO A;  4OHD A;  1Z3K A;  3PLF B;  5IBS A;  2DM0 A;  3IMD A;  5HKZ A;  3OB1 B;  3OVE A;  5D0J A;  2IUH A;  4X6S A;  2EYV A;  2DLZ A;  2H8H A;  4OHL A;  1LUN A;  2IUI A;  3BUN B;  2MRJ A;  1QCF A;  1O4B A;  1A07 A;  3US4 A;  2HCK A;  2C9W A;  1RQQ C;  2JYQ A;  4K11 A;  1BLJ A;  4XZ0 A;  2Y1M A;  4K2R A;  1X0N A;  3EAC A;  2BBU A;  2MC1 A;  1FU6 A;  1KA6 A;  1O4F A;  4E93 A;  3EAZ A;  3PSK A;  4TZI A;  1OPK A;  4D8K A;  1O4J A;  4XZ1 A;  2RSY A;  3PFV A;  4H34 A;  2HDV A;  2L4K A;  3VS3 A;  3C7I A;  4JGH A;  3CD3 A;  1SKJ A;  1NRV A;  1AYC A;  1O42 A;  5DC4 A;  1M27 A;  1I3Z A;  5I6V A;  1AYD A;  1R1Q A;  1LUM A;  1LCK A;  1BF5 A;  2IUG A;  2QMS A;  2HDX A;  1IJR A;  1RJA A;  1FU5 A;  2L3T A;  5GJH A;  4H1O A;  4DGP A;  1O4O A;  3S9K A;  2RVF A;  1LCJ A;  3GXW A;  5IBM A;  1JYQ A;  2Y3A B;  1A1E A;  1O4N A;  1UUR A;  2SHP A;  3QWX X;  5EHP A;  3BUW B;  1BKL A;  1Y57 A;  1D4W A;  1P13 A;  1KA7 A;  1A09 A;  1MW4 A;  4P9V A;  1O48 A;  4OHE A;  4A4C A;  3UF4 A;  1BHH B;  1O47 A;  3VRR A;  2CI8 A;  1GRI A;  4JEG A;  1FBV A;  3UYO A;  4U1P A;  3BUX B;  2H46 E;  2YSX A;  3BUO B;  2OQ1 A;  2LQW A;  2LNW A;  3VS4 A;  4F5A A;  1O4A A;  3S8N A;  1O4C A;  1AD5 A;  3VRO A;  2EO6 A;  3GQI B;  3PJP A;  1SHD A;  2K79 B;  4GPL B;  1X27 A;  1GHU A;  1YVL A;  1O4I A;  5EG3 B;  3HCK A;  1OO4 A;  1BFJ A;  3VRQ A;  1F2F A;  5GJI A;  1BFI A;  3IN8 A;  1R1P A;  1CSY A;  2C0I A;  1BHF A;  1CWE A;  3KFJ A;  3HHM B;  3BKB A;  1F1W A;  1O49 A;  2B3O A;  2KK6 A;  1A1C A;  3ZNI A;  2PLE A;  2C0T A;  1O4D A;  1G83 A;  2CI9 A;  2DVJ A;  3MXY A;  2HMH A;  4A4B A;  1IS0 A;  1A1A A;  1O4H A;  1Y1U A;  1NZL A;  1PIC A;  2RMX A;  3S8O A;  1BHH A;  1LUI A;  2CR4 A;  2GE9 A;  1O4K A;  1JWO A;  2CS0 A;  1XA6 A;  5BO4 A;  3VRN A;  2Y1N A;  3OV1 A;  2EOB A;  2MQI A;  1QG1 E;  2EL8 A;  2HUW A;  2DLY A;  4JE4 A;  3VS7 A;  1A08 A;  1LUK A;  4FL3 A;  3VRZ A;  2ETZ A;  3VS2 A;  1SPS A;  3BUM B;  1O4E A;  2PNA A;  2EYY A;  4NWF A;  1FBZ A;  1UUS A;  4E68 A;  1O4Q A;  5DC9 A;  4P9Z A;  1O4R A;  3PQZ A;  1FHS A;  3T04 A;  1TZE E;  1CSZ A;  2VIF A;  4QSY A;  1AOT F;  3PS5 A;  3MAZ A;  3VRY A;  2PLD A;  2XP1 A;  5DC0 B;  2MK2 A;  1JYU A; 
#chains in the Genus database with same CATH topology
 1KC2 A;  3HIZ B;  5AXI A;  4LUD A;  3NHN A;  1BG1 A;  1YVH A;  1QAD A;  2ABL A;  1KSW A;  5DF6 A;  4OHH A;  2K7A B;  1AYA A;  3QWY A;  3CXL A;  1JYR A;  4DGX A;  2IZV A;  2H5K A;  1D4T A;  2LCT A;  1LKL A;  1D1Z A;  4FL2 A;  5AUL A;  1FMK A;  1BM2 A;  1ZFP E;  2EYZ A;  3PSJ A;  1AYB A;  3OP0 A;  1A1B A;  1JU5 A;  4GWF A;  1TCE A;  2FCI A;  1SHB A;  5CDW A;  5KAZ A;  1O41 A;  3VRP A;  1M61 A;  1H9O A;  4GL9 E;  1K9A A;  1SPR A;  1MIL A;  1WQU A;  1O4P A;  3TL0 A;  2YU7 A;  2SRC A;  3CWG A;  1LKK A;  1B47 A;  4F59 A;  3MXC A;  3WA4 A;  1O43 A;  1HCT B;  1HCS B;  3M7F A;  1R1S A;  1X6C A;  4U17 A;  5EEQ A;  4OHI A;  4LUE A;  1BLK A;  1O44 A;  3LYV A;  1O4G A;  2ROR A;  4K44 A;  3N7Y A;  2LQN A;  2EKX A;  1A81 A;  4FBN A;  3VS5 A;  2PNB A;  3N8M A;  4F5B A;  2AOB A;  2EU0 A;  2KGY A;  1O45 A;  4ROJ A;  2GSB A;  2CRH A;  4EY0 A;  2AUG A;  2PTK A;  2C0O A;  3K2M A;  2CIA A;  5EHR A;  3VGO A;  1CWD L;  3GXX A;  1OO3 A;  1FYR A;  1AB2 A;  2LNX A;  3VS1 A;  2DCR A;  5HKW A;  2ECD A;  3TKZ A;  1NZV A;  1AOU F;  2KNO A;  3S8L A;  4EIH A;  3OB2 B;  1BKM A;  1CJ1 A;  2L6K A;  1BMB A;  2EO3 A;  4M4Z A;  1SHA A;  3IN7 A;  3IMJ A;  1OPL A;  3CBL A;  2DX0 A;  4WWQ A;  1O46 A;  2FO0 A;  5HKY A;  3N84 A;  4K45 A;  2CBL A;  2AOA A;  1RPY A;  4L1B B;  3VS6 A;  1O4L A;  1O4M A;  2MRK A;  4NWG A;  5EEL A;  3VS0 A;  5J3X A;  2OZO A;  4OHD A;  1Z3K A;  3PLF B;  5IBS A;  2DM0 A;  3IMD A;  5HKZ A;  3OB1 B;  3OVE A;  5D0J A;  2IUH A;  4X6S A;  2EYV A;  2DLZ A;  2H8H A;  4OHL A;  1LUN A;  2IUI A;  3BUN B;  2MRJ A;  1QCF A;  1O4B A;  1A07 A;  3US4 A;  2HCK A;  2C9W A;  1RQQ C;  2JYQ A;  4K11 A;  1BLJ A;  4XZ0 A;  2Y1M A;  4K2R A;  1X0N A;  3EAC A;  2BBU A;  2MC1 A;  1FU6 A;  1KA6 A;  1O4F A;  4E93 A;  3EAZ A;  3PSK A;  4TZI A;  1OPK A;  4D8K A;  1O4J A;  4XZ1 A;  2RSY A;  3PFV A;  4H34 A;  2HDV A;  2L4K A;  3VS3 A;  3C7I A;  4JGH A;  3CD3 A;  1SKJ A;  1NRV A;  1AYC A;  1O42 A;  5DC4 A;  1M27 A;  1I3Z A;  5I6V A;  2LRA A;  1AYD A;  1R1Q A;  1LUM A;  1LCK A;  1BF5 A;  2IUG A;  2QMS A;  2HDX A;  1IJR A;  1RJA A;  1FU5 A;  2L3T A;  5GJH A;  4H1O A;  4DGP A;  1O4O A;  3S9K A;  2RVF A;  1LCJ A;  3GXW A;  5IBM A;  1JYQ A;  2Y3A B;  1A1E A;  1O4N A;  1UUR A;  2SHP A;  3QWX X;  5EHP A;  3BUW B;  1BKL A;  1Y57 A;  1D4W A;  1P13 A;  1KA7 A;  1A09 A;  1MW4 A;  4P9V A;  1O48 A;  4OHE A;  4A4C A;  3UF4 A;  1BHH B;  1O47 A;  3VRR A;  2CI8 A;  1GRI A;  4JEG A;  1FBV A;  3UYO A;  4U1P A;  3BUX B;  2H46 E;  2YSX A;  3BUO B;  2OQ1 A;  2LQW A;  2LNW A;  3VS4 A;  4F5A A;  1O4A A;  3S8N A;  1O4C A;  1AD5 A;  3VRO A;  2EO6 A;  3GQI B;  3PJP A;  1SHD A;  2K79 B;  4GPL B;  1X27 A;  1GHU A;  1YVL A;  3K2T A;  1O4I A;  5EG3 B;  3HCK A;  1OO4 A;  1BFJ A;  3VRQ A;  1F2F A;  5GJI A;  1BFI A;  3IN8 A;  1R1P A;  1CSY A;  2C0I A;  1BHF A;  1CWE A;  3KFJ A;  3HHM B;  3BKB A;  1F1W A;  1O49 A;  2B3O A;  2KK6 A;  1A1C A;  3ZNI A;  2PLE A;  2C0T A;  1O4D A;  1G83 A;  2CI9 A;  2DVJ A;  3MXY A;  2HMH A;  4A4B A;  1IS0 A;  1A1A A;  1O4H A;  1Y1U A;  1NZL A;  1PIC A;  2RMX A;  3S8O A;  1BHH A;  1LUI A;  2CR4 A;  2GE9 A;  1O4K A;  1JWO A;  2CS0 A;  1XA6 A;  5BO4 A;  3VRN A;  2Y1N A;  3OV1 A;  2EOB A;  2MQI A;  1QG1 E;  2EL8 A;  2HUW A;  2DLY A;  4JE4 A;  3VS7 A;  1A08 A;  1LUK A;  4FL3 A;  3VRZ A;  2ETZ A;  3VS2 A;  1SPS A;  3BUM B;  1O4E A;  2PNA A;  2EYY A;  4NWF A;  1FBZ A;  1UUS A;  4E68 A;  1O4Q A;  5DC9 A;  4P9Z A;  1O4R A;  3PQZ A;  1FHS A;  3T04 A;  1TZE E;  1CSZ A;  2VIF A;  4QSY A;  1AOT F;  3PS5 A;  3MAZ A;  3VRY A;  2PLD A;  2XP1 A;  5DC0 B;  2MK2 A;  1JYU A; 
#chains in the Genus database with same CATH homology
 1KC2 A;  3HIZ B;  5AXI A;  4LUD A;  3NHN A;  1BG1 A;  1YVH A;  1QAD A;  2ABL A;  1KSW A;  5DF6 A;  4OHH A;  2K7A B;  1AYA A;  3QWY A;  3CXL A;  1JYR A;  4DGX A;  2IZV A;  2H5K A;  1D4T A;  2LCT A;  1LKL A;  1D1Z A;  4FL2 A;  5AUL A;  1FMK A;  1BM2 A;  1ZFP E;  2EYZ A;  3PSJ A;  1AYB A;  3OP0 A;  1A1B A;  1JU5 A;  4GWF A;  1TCE A;  2FCI A;  1SHB A;  5CDW A;  5KAZ A;  1O41 A;  3VRP A;  1M61 A;  1H9O A;  4GL9 E;  1K9A A;  1SPR A;  1MIL A;  1WQU A;  1O4P A;  3TL0 A;  2YU7 A;  2SRC A;  3CWG A;  1LKK A;  1B47 A;  4F59 A;  3MXC A;  3WA4 A;  1O43 A;  1HCT B;  1HCS B;  3M7F A;  1R1S A;  1X6C A;  4U17 A;  5EEQ A;  4OHI A;  4LUE A;  1BLK A;  1O44 A;  1O4G A;  2ROR A;  4K44 A;  3N7Y A;  2LQN A;  2EKX A;  1A81 A;  4FBN A;  3VS5 A;  2PNB A;  3N8M A;  4F5B A;  2AOB A;  2EU0 A;  1O45 A;  4ROJ A;  2GSB A;  2CRH A;  4EY0 A;  2AUG A;  2PTK A;  2C0O A;  3K2M A;  2CIA A;  5EHR A;  3VGO A;  1CWD L;  3GXX A;  1OO3 A;  1FYR A;  1AB2 A;  2LNX A;  3VS1 A;  2DCR A;  5HKW A;  2ECD A;  3TKZ A;  1NZV A;  1AOU F;  2KNO A;  3S8L A;  4EIH A;  3OB2 B;  1BKM A;  1CJ1 A;  2L6K A;  1BMB A;  2EO3 A;  4M4Z A;  1SHA A;  3IN7 A;  3IMJ A;  1OPL A;  3CBL A;  2DX0 A;  4WWQ A;  1O46 A;  2FO0 A;  5HKY A;  3N84 A;  4K45 A;  2CBL A;  2AOA A;  1RPY A;  4L1B B;  3VS6 A;  1O4L A;  1O4M A;  2MRK A;  4NWG A;  5EEL A;  3VS0 A;  5J3X A;  2OZO A;  4OHD A;  1Z3K A;  3PLF B;  5IBS A;  2DM0 A;  3IMD A;  5HKZ A;  3OB1 B;  3OVE A;  5D0J A;  2IUH A;  4X6S A;  2EYV A;  2DLZ A;  2H8H A;  4OHL A;  1LUN A;  2IUI A;  3BUN B;  2MRJ A;  1QCF A;  1O4B A;  1A07 A;  3US4 A;  2HCK A;  2C9W A;  1RQQ C;  2JYQ A;  4K11 A;  1BLJ A;  4XZ0 A;  2Y1M A;  4K2R A;  1X0N A;  3EAC A;  2BBU A;  2MC1 A;  1FU6 A;  1KA6 A;  1O4F A;  4E93 A;  3EAZ A;  3PSK A;  4TZI A;  1OPK A;  4D8K A;  1O4J A;  4XZ1 A;  2RSY A;  3PFV A;  4H34 A;  2HDV A;  2L4K A;  3VS3 A;  3C7I A;  4JGH A;  3CD3 A;  1SKJ A;  1NRV A;  1AYC A;  1O42 A;  5DC4 A;  1M27 A;  1I3Z A;  5I6V A;  1AYD A;  1R1Q A;  1LUM A;  1LCK A;  1BF5 A;  2IUG A;  2QMS A;  2HDX A;  1IJR A;  1RJA A;  1FU5 A;  2L3T A;  5GJH A;  4H1O A;  4DGP A;  1O4O A;  3S9K A;  2RVF A;  1LCJ A;  3GXW A;  5IBM A;  1JYQ A;  2Y3A B;  1A1E A;  1O4N A;  1UUR A;  2SHP A;  3QWX X;  5EHP A;  3BUW B;  1BKL A;  1Y57 A;  1D4W A;  1P13 A;  1KA7 A;  1A09 A;  1MW4 A;  4P9V A;  1O48 A;  4OHE A;  4A4C A;  3UF4 A;  1BHH B;  1O47 A;  3VRR A;  2CI8 A;  1GRI A;  4JEG A;  1FBV A;  3UYO A;  4U1P A;  3BUX B;  2H46 E;  2YSX A;  3BUO B;  2OQ1 A;  2LQW A;  2LNW A;  3VS4 A;  4F5A A;  1O4A A;  3S8N A;  1O4C A;  1AD5 A;  3VRO A;  2EO6 A;  3GQI B;  3PJP A;  1SHD A;  2K79 B;  4GPL B;  1X27 A;  1GHU A;  1YVL A;  1O4I A;  5EG3 B;  3HCK A;  1OO4 A;  1BFJ A;  3VRQ A;  1F2F A;  5GJI A;  1BFI A;  3IN8 A;  1R1P A;  1CSY A;  2C0I A;  1BHF A;  1CWE A;  3KFJ A;  3HHM B;  3BKB A;  1F1W A;  1O49 A;  2B3O A;  2KK6 A;  1A1C A;  3ZNI A;  2PLE A;  2C0T A;  1O4D A;  1G83 A;  2CI9 A;  2DVJ A;  3MXY A;  2HMH A;  4A4B A;  1IS0 A;  1A1A A;  1O4H A;  1Y1U A;  1NZL A;  1PIC A;  2RMX A;  3S8O A;  1BHH A;  1LUI A;  2CR4 A;  2GE9 A;  1O4K A;  1JWO A;  2CS0 A;  1XA6 A;  5BO4 A;  3VRN A;  2Y1N A;  3OV1 A;  2EOB A;  2MQI A;  1QG1 E;  2EL8 A;  2HUW A;  2DLY A;  4JE4 A;  3VS7 A;  1A08 A;  1LUK A;  4FL3 A;  3VRZ A;  2ETZ A;  3VS2 A;  1SPS A;  3BUM B;  1O4E A;  2PNA A;  2EYY A;  4NWF A;  1FBZ A;  1UUS A;  4E68 A;  1O4Q A;  5DC9 A;  4P9Z A;  1O4R A;  3PQZ A;  1FHS A;  3T04 A;  1TZE E;  1CSZ A;  2VIF A;  4QSY A;  1AOT F;  3PS5 A;  3MAZ A;  3VRY A;  2PLD A;  2XP1 A;  5DC0 B;  2MK2 A;  1JYU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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