1JYRA

Xray structure of grb2 sh2 domain complexed with a phosphorylated peptide
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
96
structure length
96
Chain Sequence
GSMAWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
pubmed doi rcsb
molecule tags Signaling protein/inhibitor
source organism Homo sapiens
molecule keywords GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
total genus 24
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2001-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1jyrA00
1CWEA 2Y3AB 1CSZA 3UF4A 1FBVA 1BLJA 3VRRA 1BHHA 4QSYA 1KA7A 5EHPA 2DX0A 3BUOB 2EYVA 2HUWA 2AUGA 4K45A 3PJPA 2IUHA 1X6CA 1SHAA 1NZLA 2PNAA 1RQQC 1O4RA 1O49A 1BKMA 4FL3A 1PICA 2YSXA 1Y57A 4GWFA 1BM2A 3NHNA 4TZIA 1X27A 1LUMA 4NWGA 1CSYA 1O4GA 1A07A 2XP1A 2RVFA 2DLYA 1O4BA 1Y1UA 4XZ1A 1R1QA 3S9KA 1FU5A 2KNOA 2EL8A 2BBUA 3VS6A 3PSKA 1O4EA 1M61A 1YVLA 2L3TA 3VS5A 5CDWA 1F1WA 1O4PA 1LUKA 1FBZA 3UYOA 1K9AA 1O4IA 2AOAA 4WWQA 3BUNB 3IMJA 1A1EA 5GJIA 1GRIA 1HCSB 1A1BA 4F59A 3CWGA 3BUWB 1BHHB 2L4KA 1O4OA 3CBLA 3GXWA 3IMDA 4P9VA 3EACA 1I3ZA 2EU0A 3HCKA 1A1AA 1KSWA 5EEQA 3T04A 3K2MA 1O4DA 2CR4A 1RJAA 1O44A 4OHLA 3KFJA 4U1PA 3ZNIA 1LUNA 3VS1A 3S8NA 4FBNA 2LQNA 1O4CA 2JYQA 1BMBA 1A09A 2FO0A 5EHRA 5KAZA 1WQUA 5J3XA 1H9OA 3BUMB 2PLDA 3HHMB 3VRYA 2IUGA 1FU6A 1A1CA 3TKZA 2HMHA 1LCKA 3GQIB 2Y1NA 5I6VA 2EO3A 3N8MA 5DC4A 1SPSA 2PLEA 3MXCA 1UURA 4OHIA 3IN8A 3VS0A 2MK2A 1QADA 1M27A 2KK6A 5DF6A 1F2FA 1SHDA 1BLKA 4K44A 3N7YA 2LNXA 4LUEA 4DGPA 2CIAA 1SPRA 1BFJA 1AYAA 2DVJA 4EIHA 2CS0A 1O4KA 1O4NA 1O4JA 1D4WA 5IBSA 4GPLB 3VRNA 2OZOA 4JEGA 2EKXA 2DCRA 2H46E 2PTKA 1AB2A 1CWDL 3CD3A 1Z3KA 5AXIA 2L6KA 3PSJA 1AOUF 4E93A 3OB1B 2YU7A 2C0IA 2EYZA 1O45A 2QMSA 3VRQA 2B3OA 3VS4A 1O47A 4OHDA 2MRKA 1UUSA 1FMKA 1XA6A 5AULA 1O4HA 2MRJA 2IZVA 3VGOA 1TCEA 4JGHA 2RORA 3OVEA 2LQWA 1HCTB 1JYQA 5HKZA 2AOBA 2RMXA 2OQ1A 3CXLA 4X6SA 1LKLA 4H34A 1AYCA 5GJHA 4K11A 2SHPA 4M4ZA 2Y1MA 1O48A 2GSBA 1O4LA 3BKBA 1NRVA 1AOTF 2LNWA 2PNBA 1BG1A 1RPYA 1P13A 2DM0A 1A81A 4D8KA 1JYUA 4ROJA 1LCJA 4OHEA 1LUIA 3QWYA 4F5AA 1OO4A 4NWFA 4OHHA 3VS7A 2VIFA 3OV1A 3VS3A 3PFVA 3WA4A 1TZEE 3MXYA 1O43A 2H5KA 1FHSA 2DLZA 1OO3A 4F5BA 2RSYA 2C0OA 2GE9A 1QCFA 4U17A 2K79B 5DC9A 1BF5A 2ETZA 2C0TA 5HKYA 2HDXA 3MAZA 1MILA 1D1ZA 1D4TA 1LKKA 1OPLA 3VROA 4H1OA 1GHUA 1O4MA 2HDVA 2IUIA 1CJ1A 2CI9A 3VRZA 5EELA 2MQIA 3S8OA 3S8LA 5HKWA 5IBMA 3US4A 3N84A 2HCKA 2ABLA 4A4BA 1SHBA 1R1PA 1OPKA 1AYBA 1AYDA 2EYYA 1X0NA 4K2RA 1B47A 1O42A 2C9WA 1AD5A 1R1SA 5BO4A 1JWOA 2ECDA 1IS0A 4EY0A 4LUDA 2H8HA 1YVHA 1KA6A 4JE4A 5D0JA 1O4AA 3GXXA 1G83A 1BHFA 2LCTA 4E68A 4P9ZA 4L1BB 3BUXB 1SKJA 1BKLA 2FCIA 1BFIA 5EG3B 1O41A 1O46A 1IJRA 2CI8A 1NZVA 1FYRA 3M7FA 3TL0A 2EOBA 1KC2A 3QWXX 1QG1E 1O4FA 3VS2A 3PS5A 3HIZB 3VRPA 1A08A 3OB2B 1JU5A 4GL9E 3OP0A 1MW4A 1ZFPE 2SRCA 3PQZA 5DC0B 4A4CA 3IN7A 1JYRA 2CBLA 3C7IA 1O4QA 2EO6A 3PLFB 2MC1A 4FL2A 3EAZA 2CRHA 4DGXA 2K7AB 4XZ0A
chains in the Genus database with same CATH superfamily
1CWEA 2Y3AB 1CSZA 3UF4A 1FBVA 1BLJA 3VRRA 1BHHA 4QSYA 1KA7A 5EHPA 2DX0A 3BUOB 3LYVA 2EYVA 2HUWA 2AUGA 4K45A 3PJPA 2IUHA 1X6CA 1SHAA 1NZLA 2PNAA 1RQQC 1O4RA 1O49A 1BKMA 4FL3A 1PICA 2YSXA 1Y57A 4GWFA 1BM2A 3NHNA 4TZIA 1X27A 1LUMA 4NWGA 1CSYA 1O4GA 1A07A 2XP1A 2RVFA 2DLYA 1O4BA 1Y1UA 4XZ1A 1R1QA 3S9KA 1FU5A 2KNOA 2EL8A 2BBUA 3VS6A 3PSKA 1O4EA 1M61A 1YVLA 2L3TA 3VS5A 5CDWA 1F1WA 1O4PA 1LUKA 1FBZA 3UYOA 1K9AA 1O4IA 2AOAA 4WWQA 3BUNB 3IMJA 1A1EA 5GJIA 1GRIA 1HCSB 1A1BA 4F59A 3CWGA 3BUWB 1BHHB 2L4KA 1O4OA 3CBLA 3GXWA 3IMDA 4P9VA 3EACA 1I3ZA 2EU0A 3HCKA 1A1AA 1KSWA 5EEQA 3T04A 3K2MA 1O4DA 2CR4A 1RJAA 1O44A 4OHLA 3KFJA 4U1PA 3ZNIA 1LUNA 3VS1A 3S8NA 4FBNA 2LQNA 1O4CA 2JYQA 1BMBA 1A09A 2FO0A 5EHRA 5KAZA 1WQUA 5J3XA 1H9OA 3BUMB 2PLDA 3HHMB 3VRYA 2IUGA 1FU6A 1A1CA 3TKZA 2HMHA 1LCKA 3GQIB 2Y1NA 5I6VA 2EO3A 3N8MA 5DC4A 1SPSA 2PLEA 3K2TA 3MXCA 1UURA 4OHIA 3IN8A 3VS0A 2MK2A 1QADA 1M27A 2KK6A 5DF6A 1F2FA 1SHDA 1BLKA 4K44A 3N7YA 2LNXA 4LUEA 4DGPA 2CIAA 1SPRA 1BFJA 1AYAA 2DVJA 4EIHA 2CS0A 1O4KA 1O4NA 1O4JA 1D4WA 5IBSA 4GPLB 3VRNA 2OZOA 4JEGA 2EKXA 2DCRA 2H46E 2PTKA 1AB2A 1CWDL 3CD3A 1Z3KA 5AXIA 2L6KA 3PSJA 1AOUF 4E93A 3OB1B 2YU7A 2C0IA 2EYZA 1O45A 2QMSA 3VRQA 2B3OA 3VS4A 1O47A 4OHDA 2MRKA 1UUSA 1FMKA 1XA6A 5AULA 1O4HA 2MRJA 2IZVA 3VGOA 1TCEA 4JGHA 2RORA 3OVEA 2LQWA 1HCTB 1JYQA 5HKZA 2AOBA 2RMXA 2OQ1A 3CXLA 4X6SA 1LKLA 4H34A 1AYCA 5GJHA 4K11A 2SHPA 4M4ZA 2Y1MA 1O48A 2GSBA 1O4LA 3BKBA 1NRVA 1AOTF 2LNWA 2PNBA 1BG1A 1RPYA 1P13A 2DM0A 1A81A 4D8KA 1JYUA 4ROJA 1LCJA 4OHEA 1LUIA 3QWYA 4F5AA 1OO4A 4NWFA 4OHHA 3VS7A 2VIFA 3OV1A 3VS3A 3PFVA 3WA4A 1TZEE 3MXYA 1O43A 2KGYA 2H5KA 1FHSA 2DLZA 1OO3A 4F5BA 2RSYA 2C0OA 2GE9A 1QCFA 4U17A 2K79B 5DC9A 1BF5A 2ETZA 2C0TA 5HKYA 2HDXA 3MAZA 1MILA 1D1ZA 1D4TA 1LKKA 1OPLA 3VROA 4H1OA 1GHUA 1O4MA 2HDVA 2IUIA 1CJ1A 2CI9A 3VRZA 5EELA 2MQIA 3S8OA 3S8LA 5HKWA 5IBMA 3US4A 3N84A 2HCKA 2ABLA 4A4BA 1SHBA 1R1PA 1OPKA 1AYBA 1AYDA 2EYYA 1X0NA 4K2RA 2LRAA 1B47A 1O42A 2C9WA 1AD5A 1R1SA 5BO4A 1JWOA 2ECDA 1IS0A 4EY0A 4LUDA 2H8HA 1YVHA 1KA6A 4JE4A 5D0JA 1O4AA 3GXXA 1G83A 1BHFA 2LCTA 4E68A 4P9ZA 4L1BB 3BUXB 1SKJA 1BKLA 2FCIA 1BFIA 5EG3B 1O41A 1O46A 1IJRA 2CI8A 1NZVA 1FYRA 3M7FA 3TL0A 2EOBA 1KC2A 3QWXX 1QG1E 1O4FA 3VS2A 3PS5A 3HIZB 3VRPA 1A08A 3OB2B 1JU5A 4GL9E 3OP0A 1MW4A 1ZFPE 2SRCA 3PQZA 5DC0B 4A4CA 3IN7A 1JYRA 2CBLA 3C7IA 1O4QA 2EO6A 3PLFB 2MC1A 4FL2A 3EAZA 2CRHA 4DGXA 2K7AB 4XZ0A
chains in the Genus database with same CATH topology
1CWEA 2Y3AB 1CSZA 3UF4A 1FBVA 1BLJA 3VRRA 1BHHA 4QSYA 1KA7A 5EHPA 2DX0A 3BUOB 2EYVA 2HUWA 2AUGA 4K45A 3PJPA 2IUHA 1X6CA 1SHAA 1NZLA 2PNAA 1RQQC 1O4RA 1O49A 1BKMA 4FL3A 1PICA 2YSXA 1Y57A 4GWFA 1BM2A 3NHNA 4TZIA 1X27A 1LUMA 4NWGA 1CSYA 1O4GA 1A07A 2XP1A 2RVFA 2DLYA 1O4BA 1Y1UA 4XZ1A 1R1QA 3S9KA 1FU5A 2KNOA 2EL8A 2BBUA 3VS6A 3PSKA 1O4EA 1M61A 1YVLA 2L3TA 3VS5A 5CDWA 1F1WA 1O4PA 1LUKA 1FBZA 3UYOA 1K9AA 1O4IA 2AOAA 4WWQA 3BUNB 3IMJA 1A1EA 5GJIA 1GRIA 1HCSB 1A1BA 4F59A 3CWGA 3BUWB 1BHHB 2L4KA 1O4OA 3CBLA 3GXWA 3IMDA 4P9VA 3EACA 1I3ZA 2EU0A 3HCKA 1A1AA 1KSWA 5EEQA 3T04A 3K2MA 1O4DA 2CR4A 1RJAA 1O44A 4OHLA 3KFJA 4U1PA 3ZNIA 1LUNA 3VS1A 3S8NA 4FBNA 2LQNA 1O4CA 2JYQA 1BMBA 1A09A 2FO0A 5EHRA 5KAZA 1WQUA 5J3XA 1H9OA 3BUMB 2PLDA 3HHMB 3VRYA 2IUGA 1FU6A 1A1CA 3TKZA 2HMHA 1LCKA 3GQIB 2Y1NA 5I6VA 2EO3A 3N8MA 5DC4A 1SPSA 2PLEA 3MXCA 1UURA 4OHIA 3IN8A 3VS0A 2MK2A 1QADA 1M27A 2KK6A 5DF6A 1F2FA 1SHDA 1BLKA 4K44A 3N7YA 2LNXA 4LUEA 4DGPA 2CIAA 1SPRA 1BFJA 1AYAA 2DVJA 4EIHA 2CS0A 1O4KA 1O4NA 1O4JA 1D4WA 5IBSA 4GPLB 3VRNA 2OZOA 4JEGA 2EKXA 2DCRA 2H46E 2PTKA 1AB2A 1CWDL 3CD3A 1Z3KA 5AXIA 2L6KA 3PSJA 1AOUF 4E93A 3OB1B 2YU7A 2C0IA 2EYZA 1O45A 2QMSA 3VRQA 2B3OA 3VS4A 1O47A 4OHDA 2MRKA 1UUSA 1FMKA 1XA6A 5AULA 1O4HA 2MRJA 2IZVA 3VGOA 1TCEA 4JGHA 2RORA 3OVEA 2LQWA 1HCTB 1JYQA 5HKZA 2AOBA 2RMXA 2OQ1A 3CXLA 4X6SA 1LKLA 4H34A 1AYCA 5GJHA 4K11A 2SHPA 4M4ZA 2Y1MA 1O48A 2GSBA 1O4LA 3BKBA 1NRVA 1AOTF 2LNWA 2PNBA 1BG1A 1RPYA 1P13A 2DM0A 1A81A 4D8KA 1JYUA 4ROJA 1LCJA 4OHEA 1LUIA 3QWYA 4F5AA 1OO4A 4NWFA 4OHHA 3VS7A 2VIFA 3OV1A 3VS3A 3PFVA 3WA4A 1TZEE 3MXYA 1O43A 2H5KA 1FHSA 2DLZA 1OO3A 4F5BA 2RSYA 2C0OA 2GE9A 1QCFA 4U17A 2K79B 5DC9A 1BF5A 2ETZA 2C0TA 5HKYA 2HDXA 3MAZA 1MILA 1D1ZA 1D4TA 1LKKA 1OPLA 3VROA 4H1OA 1GHUA 1O4MA 2HDVA 2IUIA 1CJ1A 2CI9A 3VRZA 5EELA 2MQIA 3S8OA 3S8LA 5HKWA 5IBMA 3US4A 3N84A 2HCKA 2ABLA 4A4BA 1SHBA 1R1PA 1OPKA 1AYBA 1AYDA 2EYYA 1X0NA 4K2RA 1B47A 1O42A 2C9WA 1AD5A 1R1SA 5BO4A 1JWOA 2ECDA 1IS0A 4EY0A 4LUDA 2H8HA 1YVHA 1KA6A 4JE4A 5D0JA 1O4AA 3GXXA 1G83A 1BHFA 2LCTA 4E68A 4P9ZA 4L1BB 3BUXB 1SKJA 1BKLA 2FCIA 1BFIA 5EG3B 1O41A 1O46A 1IJRA 2CI8A 1NZVA 1FYRA 3M7FA 3TL0A 2EOBA 1KC2A 3QWXX 1QG1E 1O4FA 3VS2A 3PS5A 3HIZB 3VRPA 1A08A 3OB2B 1JU5A 4GL9E 3OP0A 1MW4A 1ZFPE 2SRCA 3PQZA 5DC0B 4A4CA 3IN7A 1JYRA 2CBLA 3C7IA 1O4QA 2EO6A 3PLFB 2MC1A 4FL2A 3EAZA 2CRHA 4DGXA 2K7AB 4XZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CWE A;  2Y3A B;  1CSZ A;  3UF4 A;  1FBV A;  1BLJ A;  3VRR A;  1BHH A;  4QSY A;  1KA7 A;  5EHP A;  2DX0 A;  3BUO B;  2EYV A;  2HUW A;  2AUG A;  4K45 A;  3PJP A;  2IUH A;  1X6C A;  1SHA A;  1NZL A;  2PNA A;  1RQQ C;  1O4R A;  1O49 A;  1BKM A;  4FL3 A;  1PIC A;  2YSX A;  1Y57 A;  4GWF A;  1BM2 A;  3NHN A;  4TZI A;  1X27 A;  1LUM A;  4NWG A;  1CSY A;  1O4G A;  1A07 A;  2XP1 A;  2RVF A;  2DLY A;  1O4B A;  1Y1U A;  4XZ1 A;  1R1Q A;  3S9K A;  1FU5 A;  2KNO A;  2EL8 A;  2BBU A;  3VS6 A;  3PSK A;  1O4E A;  1M61 A;  1YVL A;  2L3T A;  3VS5 A;  5CDW A;  1F1W A;  1O4P A;  1LUK A;  1FBZ A;  3UYO A;  1K9A A;  1O4I A;  2AOA A;  4WWQ A;  3BUN B;  3IMJ A;  1A1E A;  5GJI A;  1GRI A;  1HCS B;  1A1B A;  4F59 A;  3CWG A;  3BUW B;  1BHH B;  2L4K A;  1O4O A;  3CBL A;  3GXW A;  3IMD A;  4P9V A;  3EAC A;  1I3Z A;  2EU0 A;  3HCK A;  1A1A A;  1KSW A;  5EEQ A;  3T04 A;  3K2M A;  1O4D A;  2CR4 A;  1RJA A;  1O44 A;  4OHL A;  3KFJ A;  4U1P A;  3ZNI A;  1LUN A;  3VS1 A;  3S8N A;  4FBN A;  2LQN A;  1O4C A;  2JYQ A;  1BMB A;  1A09 A;  2FO0 A;  5EHR A;  5KAZ A;  1WQU A;  5J3X A;  1H9O A;  3BUM B;  2PLD A;  3HHM B;  3VRY A;  2IUG A;  1FU6 A;  1A1C A;  3TKZ A;  2HMH A;  1LCK A;  3GQI B;  2Y1N A;  5I6V A;  2EO3 A;  3N8M A;  5DC4 A;  1SPS A;  2PLE A;  3MXC A;  1UUR A;  4OHI A;  3IN8 A;  3VS0 A;  2MK2 A;  1QAD A;  1M27 A;  2KK6 A;  5DF6 A;  1F2F A;  1SHD A;  1BLK A;  4K44 A;  3N7Y A;  2LNX A;  4LUE A;  4DGP A;  2CIA A;  1SPR A;  1BFJ A;  1AYA A;  2DVJ A;  4EIH A;  2CS0 A;  1O4K A;  1O4N A;  1O4J A;  1D4W A;  5IBS A;  4GPL B;  3VRN A;  2OZO A;  4JEG A;  2EKX A;  2DCR A;  2H46 E;  2PTK A;  1AB2 A;  1CWD L;  3CD3 A;  1Z3K A;  5AXI A;  2L6K A;  3PSJ A;  1AOU F;  4E93 A;  3OB1 B;  2YU7 A;  2C0I A;  2EYZ A;  1O45 A;  2QMS A;  3VRQ A;  2B3O A;  3VS4 A;  1O47 A;  4OHD A;  2MRK A;  1UUS A;  1FMK A;  1XA6 A;  5AUL A;  1O4H A;  2MRJ A;  2IZV A;  3VGO A;  1TCE A;  4JGH A;  2ROR A;  3OVE A;  2LQW A;  1HCT B;  1JYQ A;  5HKZ A;  2AOB A;  2RMX A;  2OQ1 A;  3CXL A;  4X6S A;  1LKL A;  4H34 A;  1AYC A;  5GJH A;  4K11 A;  2SHP A;  4M4Z A;  2Y1M A;  1O48 A;  2GSB A;  1O4L A;  3BKB A;  1NRV A;  1AOT F;  2LNW A;  2PNB A;  1BG1 A;  1RPY A;  1P13 A;  2DM0 A;  1A81 A;  4D8K A;  1JYU A;  4ROJ A;  1LCJ A;  4OHE A;  1LUI A;  3QWY A;  4F5A A;  1OO4 A;  4NWF A;  4OHH A;  3VS7 A;  2VIF A;  3OV1 A;  3VS3 A;  3PFV A;  3WA4 A;  1TZE E;  3MXY A;  1O43 A;  2H5K A;  1FHS A;  2DLZ A;  1OO3 A;  4F5B A;  2RSY A;  2C0O A;  2GE9 A;  1QCF A;  4U17 A;  2K79 B;  5DC9 A;  1BF5 A;  2ETZ A;  2C0T A;  5HKY A;  2HDX A;  3MAZ A;  1MIL A;  1D1Z A;  1D4T A;  1LKK A;  1OPL A;  3VRO A;  4H1O A;  1GHU A;  1O4M A;  2HDV A;  2IUI A;  1CJ1 A;  2CI9 A;  3VRZ A;  5EEL A;  2MQI A;  3S8O A;  3S8L A;  5HKW A;  5IBM A;  3US4 A;  3N84 A;  2HCK A;  2ABL A;  4A4B A;  1SHB A;  1R1P A;  1OPK A;  1AYB A;  1AYD A;  2EYY A;  1X0N A;  4K2R A;  1B47 A;  1O42 A;  2C9W A;  1AD5 A;  1R1S A;  5BO4 A;  1JWO A;  2ECD A;  1IS0 A;  4EY0 A;  4LUD A;  2H8H A;  1YVH A;  1KA6 A;  4JE4 A;  5D0J A;  1O4A A;  3GXX A;  1G83 A;  1BHF A;  2LCT A;  4E68 A;  4P9Z A;  4L1B B;  3BUX B;  1SKJ A;  1BKL A;  2FCI A;  1BFI A;  5EG3 B;  1O41 A;  1O46 A;  1IJR A;  2CI8 A;  1NZV A;  1FYR A;  3M7F A;  3TL0 A;  2EOB A;  1KC2 A;  3QWX X;  1QG1 E;  1O4F A;  3VS2 A;  3PS5 A;  3HIZ B;  3VRP A;  1A08 A;  3OB2 B;  1JU5 A;  4GL9 E;  3OP0 A;  1MW4 A;  1ZFP E;  2SRC A;  3PQZ A;  5DC0 B;  4A4C A;  3IN7 A;  1JYR A;  2CBL A;  3C7I A;  1O4Q A;  2EO6 A;  3PLF B;  2MC1 A;  4FL2 A;  3EAZ A;  2CRH A;  4DGX A;  2K7A B;  4XZ0 A; 
#chains in the Genus database with same CATH topology
 1CWE A;  2Y3A B;  1CSZ A;  3UF4 A;  1FBV A;  1BLJ A;  3VRR A;  1BHH A;  4QSY A;  1KA7 A;  5EHP A;  2DX0 A;  3BUO B;  3LYV A;  2EYV A;  2HUW A;  2AUG A;  4K45 A;  3PJP A;  2IUH A;  1X6C A;  1SHA A;  1NZL A;  2PNA A;  1RQQ C;  1O4R A;  1O49 A;  1BKM A;  4FL3 A;  1PIC A;  2YSX A;  1Y57 A;  4GWF A;  1BM2 A;  3NHN A;  4TZI A;  1X27 A;  1LUM A;  4NWG A;  1CSY A;  1O4G A;  1A07 A;  2XP1 A;  2RVF A;  2DLY A;  1O4B A;  1Y1U A;  4XZ1 A;  1R1Q A;  3S9K A;  1FU5 A;  2KNO A;  2EL8 A;  2BBU A;  3VS6 A;  3PSK A;  1O4E A;  1M61 A;  1YVL A;  2L3T A;  3VS5 A;  5CDW A;  1F1W A;  1O4P A;  1LUK A;  1FBZ A;  3UYO A;  1K9A A;  1O4I A;  2AOA A;  4WWQ A;  3BUN B;  3IMJ A;  1A1E A;  5GJI A;  1GRI A;  1HCS B;  1A1B A;  4F59 A;  3CWG A;  3BUW B;  1BHH B;  2L4K A;  1O4O A;  3CBL A;  3GXW A;  3IMD A;  4P9V A;  3EAC A;  1I3Z A;  2EU0 A;  3HCK A;  1A1A A;  1KSW A;  5EEQ A;  3T04 A;  3K2M A;  1O4D A;  2CR4 A;  1RJA A;  1O44 A;  4OHL A;  3KFJ A;  4U1P A;  3ZNI A;  1LUN A;  3VS1 A;  3S8N A;  4FBN A;  2LQN A;  1O4C A;  2JYQ A;  1BMB A;  1A09 A;  2FO0 A;  5EHR A;  5KAZ A;  1WQU A;  5J3X A;  1H9O A;  3BUM B;  2PLD A;  3HHM B;  3VRY A;  2IUG A;  1FU6 A;  1A1C A;  3TKZ A;  2HMH A;  1LCK A;  3GQI B;  2Y1N A;  5I6V A;  2EO3 A;  3N8M A;  5DC4 A;  1SPS A;  2PLE A;  3K2T A;  3MXC A;  1UUR A;  4OHI A;  3IN8 A;  3VS0 A;  2MK2 A;  1QAD A;  1M27 A;  2KK6 A;  5DF6 A;  1F2F A;  1SHD A;  1BLK A;  4K44 A;  3N7Y A;  2LNX A;  4LUE A;  4DGP A;  2CIA A;  1SPR A;  1BFJ A;  1AYA A;  2DVJ A;  4EIH A;  2CS0 A;  1O4K A;  1O4N A;  1O4J A;  1D4W A;  5IBS A;  4GPL B;  3VRN A;  2OZO A;  4JEG A;  2EKX A;  2DCR A;  2H46 E;  2PTK A;  1AB2 A;  1CWD L;  3CD3 A;  1Z3K A;  5AXI A;  2L6K A;  3PSJ A;  1AOU F;  4E93 A;  3OB1 B;  2YU7 A;  2C0I A;  2EYZ A;  1O45 A;  2QMS A;  3VRQ A;  2B3O A;  3VS4 A;  1O47 A;  4OHD A;  2MRK A;  1UUS A;  1FMK A;  1XA6 A;  5AUL A;  1O4H A;  2MRJ A;  2IZV A;  3VGO A;  1TCE A;  4JGH A;  2ROR A;  3OVE A;  2LQW A;  1HCT B;  1JYQ A;  5HKZ A;  2AOB A;  2RMX A;  2OQ1 A;  3CXL A;  4X6S A;  1LKL A;  4H34 A;  1AYC A;  5GJH A;  4K11 A;  2SHP A;  4M4Z A;  2Y1M A;  1O48 A;  2GSB A;  1O4L A;  3BKB A;  1NRV A;  1AOT F;  2LNW A;  2PNB A;  1BG1 A;  1RPY A;  1P13 A;  2DM0 A;  1A81 A;  4D8K A;  1JYU A;  4ROJ A;  1LCJ A;  4OHE A;  1LUI A;  3QWY A;  4F5A A;  1OO4 A;  4NWF A;  4OHH A;  3VS7 A;  2VIF A;  3OV1 A;  3VS3 A;  3PFV A;  3WA4 A;  1TZE E;  3MXY A;  1O43 A;  2KGY A;  2H5K A;  1FHS A;  2DLZ A;  1OO3 A;  4F5B A;  2RSY A;  2C0O A;  2GE9 A;  1QCF A;  4U17 A;  2K79 B;  5DC9 A;  1BF5 A;  2ETZ A;  2C0T A;  5HKY A;  2HDX A;  3MAZ A;  1MIL A;  1D1Z A;  1D4T A;  1LKK A;  1OPL A;  3VRO A;  4H1O A;  1GHU A;  1O4M A;  2HDV A;  2IUI A;  1CJ1 A;  2CI9 A;  3VRZ A;  5EEL A;  2MQI A;  3S8O A;  3S8L A;  5HKW A;  5IBM A;  3US4 A;  3N84 A;  2HCK A;  2ABL A;  4A4B A;  1SHB A;  1R1P A;  1OPK A;  1AYB A;  1AYD A;  2EYY A;  1X0N A;  4K2R A;  2LRA A;  1B47 A;  1O42 A;  2C9W A;  1AD5 A;  1R1S A;  5BO4 A;  1JWO A;  2ECD A;  1IS0 A;  4EY0 A;  4LUD A;  2H8H A;  1YVH A;  1KA6 A;  4JE4 A;  5D0J A;  1O4A A;  3GXX A;  1G83 A;  1BHF A;  2LCT A;  4E68 A;  4P9Z A;  4L1B B;  3BUX B;  1SKJ A;  1BKL A;  2FCI A;  1BFI A;  5EG3 B;  1O41 A;  1O46 A;  1IJR A;  2CI8 A;  1NZV A;  1FYR A;  3M7F A;  3TL0 A;  2EOB A;  1KC2 A;  3QWX X;  1QG1 E;  1O4F A;  3VS2 A;  3PS5 A;  3HIZ B;  3VRP A;  1A08 A;  3OB2 B;  1JU5 A;  4GL9 E;  3OP0 A;  1MW4 A;  1ZFP E;  2SRC A;  3PQZ A;  5DC0 B;  4A4C A;  3IN7 A;  1JYR A;  2CBL A;  3C7I A;  1O4Q A;  2EO6 A;  3PLF B;  2MC1 A;  4FL2 A;  3EAZ A;  2CRH A;  4DGX A;  2K7A B;  4XZ0 A; 
#chains in the Genus database with same CATH homology
 1CWE A;  2Y3A B;  1CSZ A;  3UF4 A;  1FBV A;  1BLJ A;  3VRR A;  1BHH A;  4QSY A;  1KA7 A;  5EHP A;  2DX0 A;  3BUO B;  2EYV A;  2HUW A;  2AUG A;  4K45 A;  3PJP A;  2IUH A;  1X6C A;  1SHA A;  1NZL A;  2PNA A;  1RQQ C;  1O4R A;  1O49 A;  1BKM A;  4FL3 A;  1PIC A;  2YSX A;  1Y57 A;  4GWF A;  1BM2 A;  3NHN A;  4TZI A;  1X27 A;  1LUM A;  4NWG A;  1CSY A;  1O4G A;  1A07 A;  2XP1 A;  2RVF A;  2DLY A;  1O4B A;  1Y1U A;  4XZ1 A;  1R1Q A;  3S9K A;  1FU5 A;  2KNO A;  2EL8 A;  2BBU A;  3VS6 A;  3PSK A;  1O4E A;  1M61 A;  1YVL A;  2L3T A;  3VS5 A;  5CDW A;  1F1W A;  1O4P A;  1LUK A;  1FBZ A;  3UYO A;  1K9A A;  1O4I A;  2AOA A;  4WWQ A;  3BUN B;  3IMJ A;  1A1E A;  5GJI A;  1GRI A;  1HCS B;  1A1B A;  4F59 A;  3CWG A;  3BUW B;  1BHH B;  2L4K A;  1O4O A;  3CBL A;  3GXW A;  3IMD A;  4P9V A;  3EAC A;  1I3Z A;  2EU0 A;  3HCK A;  1A1A A;  1KSW A;  5EEQ A;  3T04 A;  3K2M A;  1O4D A;  2CR4 A;  1RJA A;  1O44 A;  4OHL A;  3KFJ A;  4U1P A;  3ZNI A;  1LUN A;  3VS1 A;  3S8N A;  4FBN A;  2LQN A;  1O4C A;  2JYQ A;  1BMB A;  1A09 A;  2FO0 A;  5EHR A;  5KAZ A;  1WQU A;  5J3X A;  1H9O A;  3BUM B;  2PLD A;  3HHM B;  3VRY A;  2IUG A;  1FU6 A;  1A1C A;  3TKZ A;  2HMH A;  1LCK A;  3GQI B;  2Y1N A;  5I6V A;  2EO3 A;  3N8M A;  5DC4 A;  1SPS A;  2PLE A;  3MXC A;  1UUR A;  4OHI A;  3IN8 A;  3VS0 A;  2MK2 A;  1QAD A;  1M27 A;  2KK6 A;  5DF6 A;  1F2F A;  1SHD A;  1BLK A;  4K44 A;  3N7Y A;  2LNX A;  4LUE A;  4DGP A;  2CIA A;  1SPR A;  1BFJ A;  1AYA A;  2DVJ A;  4EIH A;  2CS0 A;  1O4K A;  1O4N A;  1O4J A;  1D4W A;  5IBS A;  4GPL B;  3VRN A;  2OZO A;  4JEG A;  2EKX A;  2DCR A;  2H46 E;  2PTK A;  1AB2 A;  1CWD L;  3CD3 A;  1Z3K A;  5AXI A;  2L6K A;  3PSJ A;  1AOU F;  4E93 A;  3OB1 B;  2YU7 A;  2C0I A;  2EYZ A;  1O45 A;  2QMS A;  3VRQ A;  2B3O A;  3VS4 A;  1O47 A;  4OHD A;  2MRK A;  1UUS A;  1FMK A;  1XA6 A;  5AUL A;  1O4H A;  2MRJ A;  2IZV A;  3VGO A;  1TCE A;  4JGH A;  2ROR A;  3OVE A;  2LQW A;  1HCT B;  1JYQ A;  5HKZ A;  2AOB A;  2RMX A;  2OQ1 A;  3CXL A;  4X6S A;  1LKL A;  4H34 A;  1AYC A;  5GJH A;  4K11 A;  2SHP A;  4M4Z A;  2Y1M A;  1O48 A;  2GSB A;  1O4L A;  3BKB A;  1NRV A;  1AOT F;  2LNW A;  2PNB A;  1BG1 A;  1RPY A;  1P13 A;  2DM0 A;  1A81 A;  4D8K A;  1JYU A;  4ROJ A;  1LCJ A;  4OHE A;  1LUI A;  3QWY A;  4F5A A;  1OO4 A;  4NWF A;  4OHH A;  3VS7 A;  2VIF A;  3OV1 A;  3VS3 A;  3PFV A;  3WA4 A;  1TZE E;  3MXY A;  1O43 A;  2H5K A;  1FHS A;  2DLZ A;  1OO3 A;  4F5B A;  2RSY A;  2C0O A;  2GE9 A;  1QCF A;  4U17 A;  2K79 B;  5DC9 A;  1BF5 A;  2ETZ A;  2C0T A;  5HKY A;  2HDX A;  3MAZ A;  1MIL A;  1D1Z A;  1D4T A;  1LKK A;  1OPL A;  3VRO A;  4H1O A;  1GHU A;  1O4M A;  2HDV A;  2IUI A;  1CJ1 A;  2CI9 A;  3VRZ A;  5EEL A;  2MQI A;  3S8O A;  3S8L A;  5HKW A;  5IBM A;  3US4 A;  3N84 A;  2HCK A;  2ABL A;  4A4B A;  1SHB A;  1R1P A;  1OPK A;  1AYB A;  1AYD A;  2EYY A;  1X0N A;  4K2R A;  1B47 A;  1O42 A;  2C9W A;  1AD5 A;  1R1S A;  5BO4 A;  1JWO A;  2ECD A;  1IS0 A;  4EY0 A;  4LUD A;  2H8H A;  1YVH A;  1KA6 A;  4JE4 A;  5D0J A;  1O4A A;  3GXX A;  1G83 A;  1BHF A;  2LCT A;  4E68 A;  4P9Z A;  4L1B B;  3BUX B;  1SKJ A;  1BKL A;  2FCI A;  1BFI A;  5EG3 B;  1O41 A;  1O46 A;  1IJR A;  2CI8 A;  1NZV A;  1FYR A;  3M7F A;  3TL0 A;  2EOB A;  1KC2 A;  3QWX X;  1QG1 E;  1O4F A;  3VS2 A;  3PS5 A;  3HIZ B;  3VRP A;  1A08 A;  3OB2 B;  1JU5 A;  4GL9 E;  3OP0 A;  1MW4 A;  1ZFP E;  2SRC A;  3PQZ A;  5DC0 B;  4A4C A;  3IN7 A;  1JYR A;  2CBL A;  3C7I A;  1O4Q A;  2EO6 A;  3PLF B;  2MC1 A;  4FL2 A;  3EAZ A;  2CRH A;  4DGX A;  2K7A B;  4XZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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