1O4EA

Crystal structure of sh2 in complex with ru78299.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
molecule tags Signaling protein
source organism Homo sapiens
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4eA00
1OO3A 3MXYA 5DC0B 1BKLA 2VIFA 2EYVA 1A07A 1JYUA 2MQIA 2IUGA 5GJHA 3PSKA 2EYYA 1FYRA 2K79B 4U17A 1JYRA 2LCTA 2AOAA 2RSYA 1HCSB 1CJ1A 5HKWA 1QCFA 5EHPA 1A09A 1AB2A 4XZ0A 2LQWA 1AYCA 4NWGA 3VRPA 1M27A 4JGHA 3OB1B 3GQIB 3VS4A 3T04A 1AYDA 1OPKA 5I6VA 1D1ZA 3VS5A 1O46A 2PTKA 1Z3KA 4E68A 4ROJA 1F1WA 1YVHA 2FCIA 2CI8A 3BUMB 2MRKA 1O4EA 2L6KA 1YVLA 1SHDA 3S8NA 2HMHA 5KAZA 5D0JA 1KA7A 5IBMA 1BG1A 2CI9A 2L4KA 2XP1A 5EELA 1O4DA 1A1EA 1CSYA 4GWFA 2FO0A 2AOBA 3NHNA 4K2RA 2IUIA 2YU7A 2EOBA 3EACA 1D4TA 1A08A 3GXWA 3QWXX 2DLZA 4H34A 1A1AA 1OPLA 3MXCA 1FU5A 2CRHA 2RMXA 3PLFB 2HDXA 1GRIA 1AYAA 1BHHA 2ABLA 1O4MA 3OVEA 2HDVA 2EU0A 4QSYA 2IZVA 3BKBA 2DVJA 4FL2A 4K45A 2L3TA 2EKXA 2Y3AB 1LCKA 2C0IA 4P9ZA 4K11A 2ECDA 3N7YA 4LUEA 1AD5A 4NWFA 1O47A 3S8OA 4LUDA 2OQ1A 1CSZA 1FBVA 3PQZA 4FBNA 3IMDA 1M61A 3VS2A 2CS0A 1RPYA 1F2FA 1BHHB 4D8KA 3CD3A 4H1OA 2CBLA 1LCJA 4X6SA 1KSWA 3CWGA 2OZOA 1X6CA 1ZFPE 2IUHA 4WWQA 5BO4A 1R1SA 1X0NA 2KNOA 3UF4A 3VS3A 2BBUA 2LQNA 4F59A 2EYZA 3US4A 1AOUF 2QMSA 3PS5A 4L1BB 4A4BA 2PNBA 4JEGA 3S8LA 2KK6A 2AUGA 3BUNB 1BKMA 3OP0A 5DC4A 1FMKA 3VS6A 1BHFA 4GPLB 2K7AB 4OHLA 3TKZA 2LNXA 2ETZA 1G83A 4TZIA 2B3OA 1O4KA 1XA6A 4OHDA 4U1PA 1LUNA 1SHBA 1A81A 1O43A 3OB2B 1O4JA 4JE4A 3PJPA 4DGPA 1LUKA 3WA4A 4P9VA 1BMBA 1LUMA 3VRQA 1CWDL 4OHIA 2Y1NA 1BFJA 2PLEA 1LKLA 5IBSA 1O45A 3VS1A 1WQUA 3HHMB 1KC2A 1O4FA 3HCKA 4OHEA 2MK2A 2H5KA 1O4GA 2EO3A 2GSBA 1BM2A 1O4OA 3BUWB 3C7IA 3UYOA 1IS0A 1O4NA 2Y1MA 3M7FA 3MAZA 3TL0A 2H46E 2SRCA 1O42A 3IMJA 3K2MA 1A1BA 2PNAA 1O4HA 2DM0A 3QWYA 2EL8A 1FBZA 2DX0A 2RVFA 1A1CA 1R1QA 2DLYA 5J3XA 1O4IA 1JU5A 5AULA 3KFJA 5EHRA 3S9KA 4OHHA 4GL9E 2H8HA 2HUWA 1O4QA 1AYBA 2GE9A 4FL3A 2JYQA 1LUIA 2RORA 5DC9A 1O4AA 1O41A 1X27A 1UURA 1TZEE 1FU6A 2C0OA 1H9OA 1O48A 4M4ZA 4DGXA 3N84A 5HKYA 1LKKA 1MW4A 1O4LA 2MRJA 2PLDA 1O4CA 1O49A 1SPRA 1O44A 3GXXA 1OO4A 1CWEA 3OV1A 3IN8A 1QADA 1I3ZA 4F5AA 3VRZA 1GHUA 1D4WA 3CBLA 3CXLA 1QG1E 1K9AA 3HIZB 1PICA 5GJIA 3PSJA 1NRVA 2C0TA 3EAZA 2MC1A 2C9WA 3VRRA 1RJAA 2CR4A 1IJRA 3ZNIA 1P13A 4K44A 4EIHA 1B47A 1RQQC 3BUXB 1HCTB 3VRNA 1KA6A 4EY0A 1FHSA 1SHAA 2CIAA 5AXIA 3VROA 1MILA 4XZ1A 5HKZA 1AOTF 1BFIA 3VRYA 3IN7A 3VS7A 1BF5A 1Y57A 1O4BA 1JWOA 1NZLA 1O4PA 1SPSA 2HCKA 4E93A 1TCEA 1BLKA 1O4RA 1SKJA 5EEQA 1R1PA 1NZVA 1JYQA 2SHPA 4A4CA 2YSXA 5EG3B 3PFVA 5CDWA 4F5BA 1Y1UA 5DF6A 2LNWA 3VS0A 1BLJA 2DCRA 3VGOA 2EO6A 3BUOB 1UUSA 3N8MA
chains in the Genus database with same CATH superfamily
1OO3A 3MXYA 5DC0B 1BKLA 2VIFA 2EYVA 1A07A 1JYUA 2MQIA 2IUGA 5GJHA 3PSKA 2EYYA 1FYRA 2K79B 4U17A 1JYRA 2LCTA 2AOAA 2RSYA 1HCSB 1CJ1A 5HKWA 1QCFA 5EHPA 1A09A 1AB2A 4XZ0A 2LQWA 1AYCA 4NWGA 3VRPA 1M27A 4JGHA 3OB1B 3GQIB 3VS4A 3T04A 1AYDA 1OPKA 5I6VA 1D1ZA 3VS5A 1O46A 2PTKA 1Z3KA 4E68A 4ROJA 1F1WA 1YVHA 2FCIA 2CI8A 3BUMB 2MRKA 1O4EA 2L6KA 1YVLA 1SHDA 3S8NA 2HMHA 5KAZA 5D0JA 1KA7A 5IBMA 1BG1A 2CI9A 2L4KA 2XP1A 5EELA 1O4DA 1A1EA 1CSYA 4GWFA 2FO0A 2AOBA 3NHNA 4K2RA 2IUIA 2YU7A 2EOBA 3EACA 1D4TA 1A08A 3GXWA 3QWXX 2DLZA 4H34A 1A1AA 1OPLA 3MXCA 1FU5A 2CRHA 2RMXA 3PLFB 2HDXA 1GRIA 1AYAA 1BHHA 2ABLA 1O4MA 3OVEA 2HDVA 2EU0A 4QSYA 2IZVA 3BKBA 2DVJA 4FL2A 4K45A 2L3TA 2EKXA 2Y3AB 1LCKA 2C0IA 4P9ZA 4K11A 2ECDA 3N7YA 4LUEA 1AD5A 4NWFA 1O47A 3S8OA 4LUDA 2OQ1A 1CSZA 1FBVA 3PQZA 4FBNA 3IMDA 1M61A 3VS2A 2CS0A 1RPYA 1F2FA 1BHHB 4D8KA 3CD3A 4H1OA 2CBLA 1LCJA 4X6SA 1KSWA 3CWGA 2OZOA 1X6CA 1ZFPE 2IUHA 4WWQA 5BO4A 1R1SA 1X0NA 2KNOA 3UF4A 3VS3A 2BBUA 2LQNA 4F59A 2EYZA 3US4A 1AOUF 2QMSA 3PS5A 4L1BB 4A4BA 2PNBA 4JEGA 3S8LA 2KK6A 2AUGA 3BUNB 1BKMA 3OP0A 5DC4A 1FMKA 3VS6A 1BHFA 4GPLB 2K7AB 4OHLA 3TKZA 2LNXA 2ETZA 1G83A 4TZIA 2B3OA 1O4KA 1XA6A 4OHDA 4U1PA 1LUNA 1SHBA 1A81A 1O43A 3OB2B 1O4JA 4JE4A 3PJPA 4DGPA 1LUKA 3WA4A 4P9VA 1BMBA 1LUMA 3VRQA 1CWDL 4OHIA 2Y1NA 1BFJA 2PLEA 1LKLA 5IBSA 1O45A 3VS1A 1WQUA 3HHMB 1KC2A 1O4FA 3HCKA 4OHEA 2MK2A 2H5KA 1O4GA 2EO3A 2GSBA 1BM2A 1O4OA 3BUWB 3C7IA 3UYOA 1IS0A 1O4NA 2Y1MA 3M7FA 3MAZA 3TL0A 2H46E 2SRCA 1O42A 3IMJA 3K2MA 1A1BA 2PNAA 1O4HA 2DM0A 3QWYA 2EL8A 1FBZA 3LYVA 2DX0A 2RVFA 1A1CA 1R1QA 2DLYA 5J3XA 1O4IA 1JU5A 5AULA 3KFJA 5EHRA 3S9KA 4OHHA 4GL9E 2H8HA 2HUWA 1O4QA 1AYBA 2GE9A 4FL3A 2JYQA 1LUIA 2RORA 5DC9A 1O4AA 1O41A 1X27A 1UURA 1TZEE 1FU6A 2C0OA 1H9OA 1O48A 4M4ZA 4DGXA 3N84A 5HKYA 1LKKA 1MW4A 1O4LA 2MRJA 2PLDA 1O4CA 1O49A 1SPRA 1O44A 3GXXA 1OO4A 1CWEA 3OV1A 3IN8A 1QADA 1I3ZA 4F5AA 3VRZA 1GHUA 1D4WA 3CBLA 3CXLA 1QG1E 1K9AA 3HIZB 2KGYA 1PICA 5GJIA 3PSJA 1NRVA 2C0TA 3EAZA 2MC1A 2C9WA 3VRRA 1RJAA 2CR4A 1IJRA 3ZNIA 3K2TA 1P13A 4K44A 4EIHA 1B47A 1RQQC 3BUXB 1HCTB 3VRNA 1KA6A 4EY0A 1FHSA 1SHAA 2CIAA 5AXIA 3VROA 1MILA 4XZ1A 5HKZA 1AOTF 1BFIA 3VRYA 3IN7A 3VS7A 1BF5A 1Y57A 1O4BA 1JWOA 2LRAA 1NZLA 1O4PA 1SPSA 2HCKA 4E93A 1TCEA 1BLKA 1O4RA 1SKJA 5EEQA 1R1PA 1NZVA 1JYQA 2SHPA 4A4CA 2YSXA 5EG3B 3PFVA 5CDWA 4F5BA 1Y1UA 5DF6A 2LNWA 3VS0A 1BLJA 2DCRA 3VGOA 2EO6A 3BUOB 1UUSA 3N8MA
chains in the Genus database with same CATH topology
1OO3A 3MXYA 5DC0B 1BKLA 2VIFA 2EYVA 1A07A 1JYUA 2MQIA 2IUGA 5GJHA 3PSKA 2EYYA 1FYRA 2K79B 4U17A 1JYRA 2LCTA 2AOAA 2RSYA 1HCSB 1CJ1A 5HKWA 1QCFA 5EHPA 1A09A 1AB2A 4XZ0A 2LQWA 1AYCA 4NWGA 3VRPA 1M27A 4JGHA 3OB1B 3GQIB 3VS4A 3T04A 1AYDA 1OPKA 5I6VA 1D1ZA 3VS5A 1O46A 2PTKA 1Z3KA 4E68A 4ROJA 1F1WA 1YVHA 2FCIA 2CI8A 3BUMB 2MRKA 1O4EA 2L6KA 1YVLA 1SHDA 3S8NA 2HMHA 5KAZA 5D0JA 1KA7A 5IBMA 1BG1A 2CI9A 2L4KA 2XP1A 5EELA 1O4DA 1A1EA 1CSYA 4GWFA 2FO0A 2AOBA 3NHNA 4K2RA 2IUIA 2YU7A 2EOBA 3EACA 1D4TA 1A08A 3GXWA 3QWXX 2DLZA 4H34A 1A1AA 1OPLA 3MXCA 1FU5A 2CRHA 2RMXA 3PLFB 2HDXA 1GRIA 1AYAA 1BHHA 2ABLA 1O4MA 3OVEA 2HDVA 2EU0A 4QSYA 2IZVA 3BKBA 2DVJA 4FL2A 4K45A 2L3TA 2EKXA 2Y3AB 1LCKA 2C0IA 4P9ZA 4K11A 2ECDA 3N7YA 4LUEA 1AD5A 4NWFA 1O47A 3S8OA 4LUDA 2OQ1A 1CSZA 1FBVA 3PQZA 4FBNA 3IMDA 1M61A 3VS2A 2CS0A 1RPYA 1F2FA 1BHHB 4D8KA 3CD3A 4H1OA 2CBLA 1LCJA 4X6SA 1KSWA 3CWGA 2OZOA 1X6CA 1ZFPE 2IUHA 4WWQA 5BO4A 1R1SA 1X0NA 2KNOA 3UF4A 3VS3A 2BBUA 2LQNA 4F59A 2EYZA 3US4A 1AOUF 2QMSA 3PS5A 4L1BB 4A4BA 2PNBA 4JEGA 3S8LA 2KK6A 2AUGA 3BUNB 1BKMA 3OP0A 5DC4A 1FMKA 3VS6A 1BHFA 4GPLB 2K7AB 4OHLA 3TKZA 2LNXA 2ETZA 1G83A 4TZIA 2B3OA 1O4KA 1XA6A 4OHDA 4U1PA 1LUNA 1SHBA 1A81A 1O43A 3OB2B 1O4JA 4JE4A 3PJPA 4DGPA 1LUKA 3WA4A 4P9VA 1BMBA 1LUMA 3VRQA 1CWDL 4OHIA 2Y1NA 1BFJA 2PLEA 1LKLA 5IBSA 1O45A 3VS1A 1WQUA 3HHMB 1KC2A 1O4FA 3HCKA 4OHEA 2MK2A 2H5KA 1O4GA 2EO3A 2GSBA 1BM2A 1O4OA 3BUWB 3C7IA 3UYOA 1IS0A 1O4NA 2Y1MA 3M7FA 3MAZA 3TL0A 2H46E 2SRCA 1O42A 3IMJA 3K2MA 1A1BA 2PNAA 1O4HA 2DM0A 3QWYA 2EL8A 1FBZA 2DX0A 2RVFA 1A1CA 1R1QA 2DLYA 5J3XA 1O4IA 1JU5A 5AULA 3KFJA 5EHRA 3S9KA 4OHHA 4GL9E 2H8HA 2HUWA 1O4QA 1AYBA 2GE9A 4FL3A 2JYQA 1LUIA 2RORA 5DC9A 1O4AA 1O41A 1X27A 1UURA 1TZEE 1FU6A 2C0OA 1H9OA 1O48A 4M4ZA 4DGXA 3N84A 5HKYA 1LKKA 1MW4A 1O4LA 2MRJA 2PLDA 1O4CA 1O49A 1SPRA 1O44A 3GXXA 1OO4A 1CWEA 3OV1A 3IN8A 1QADA 1I3ZA 4F5AA 3VRZA 1GHUA 1D4WA 3CBLA 3CXLA 1QG1E 1K9AA 3HIZB 1PICA 5GJIA 3PSJA 1NRVA 2C0TA 3EAZA 2MC1A 2C9WA 3VRRA 1RJAA 2CR4A 1IJRA 3ZNIA 1P13A 4K44A 4EIHA 1B47A 1RQQC 3BUXB 1HCTB 3VRNA 1KA6A 4EY0A 1FHSA 1SHAA 2CIAA 5AXIA 3VROA 1MILA 4XZ1A 5HKZA 1AOTF 1BFIA 3VRYA 3IN7A 3VS7A 1BF5A 1Y57A 1O4BA 1JWOA 1NZLA 1O4PA 1SPSA 2HCKA 4E93A 1TCEA 1BLKA 1O4RA 1SKJA 5EEQA 1R1PA 1NZVA 1JYQA 2SHPA 4A4CA 2YSXA 5EG3B 3PFVA 5CDWA 4F5BA 1Y1UA 5DF6A 2LNWA 3VS0A 1BLJA 2DCRA 3VGOA 2EO6A 3BUOB 1UUSA 3N8MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OO3 A;  3MXY A;  5DC0 B;  1BKL A;  2VIF A;  2EYV A;  1A07 A;  1JYU A;  2MQI A;  2IUG A;  5GJH A;  3PSK A;  2EYY A;  1FYR A;  2K79 B;  4U17 A;  1JYR A;  2LCT A;  2AOA A;  2RSY A;  1HCS B;  1CJ1 A;  5HKW A;  1QCF A;  5EHP A;  1A09 A;  1AB2 A;  4XZ0 A;  2LQW A;  1AYC A;  4NWG A;  3VRP A;  1M27 A;  4JGH A;  3OB1 B;  3GQI B;  3VS4 A;  3T04 A;  1AYD A;  1OPK A;  5I6V A;  1D1Z A;  3VS5 A;  1O46 A;  2PTK A;  1Z3K A;  4E68 A;  4ROJ A;  1F1W A;  1YVH A;  2FCI A;  2CI8 A;  3BUM B;  2MRK A;  1O4E A;  2L6K A;  1YVL A;  1SHD A;  3S8N A;  2HMH A;  5KAZ A;  5D0J A;  1KA7 A;  5IBM A;  1BG1 A;  2CI9 A;  2L4K A;  2XP1 A;  5EEL A;  1O4D A;  1A1E A;  1CSY A;  4GWF A;  2FO0 A;  2AOB A;  3NHN A;  4K2R A;  2IUI A;  2YU7 A;  2EOB A;  3EAC A;  1D4T A;  1A08 A;  3GXW A;  3QWX X;  2DLZ A;  4H34 A;  1A1A A;  1OPL A;  3MXC A;  1FU5 A;  2CRH A;  2RMX A;  3PLF B;  2HDX A;  1GRI A;  1AYA A;  1BHH A;  2ABL A;  1O4M A;  3OVE A;  2HDV A;  2EU0 A;  4QSY A;  2IZV A;  3BKB A;  2DVJ A;  4FL2 A;  4K45 A;  2L3T A;  2EKX A;  2Y3A B;  1LCK A;  2C0I A;  4P9Z A;  4K11 A;  2ECD A;  3N7Y A;  4LUE A;  1AD5 A;  4NWF A;  1O47 A;  3S8O A;  4LUD A;  2OQ1 A;  1CSZ A;  1FBV A;  3PQZ A;  4FBN A;  3IMD A;  1M61 A;  3VS2 A;  2CS0 A;  1RPY A;  1F2F A;  1BHH B;  4D8K A;  3CD3 A;  4H1O A;  2CBL A;  1LCJ A;  4X6S A;  1KSW A;  3CWG A;  2OZO A;  1X6C A;  1ZFP E;  2IUH A;  4WWQ A;  5BO4 A;  1R1S A;  1X0N A;  2KNO A;  3UF4 A;  3VS3 A;  2BBU A;  2LQN A;  4F59 A;  2EYZ A;  3US4 A;  1AOU F;  2QMS A;  3PS5 A;  4L1B B;  4A4B A;  2PNB A;  4JEG A;  3S8L A;  2KK6 A;  2AUG A;  3BUN B;  1BKM A;  3OP0 A;  5DC4 A;  1FMK A;  3VS6 A;  1BHF A;  4GPL B;  2K7A B;  4OHL A;  3TKZ A;  2LNX A;  2ETZ A;  1G83 A;  4TZI A;  2B3O A;  1O4K A;  1XA6 A;  4OHD A;  4U1P A;  1LUN A;  1SHB A;  1A81 A;  1O43 A;  3OB2 B;  1O4J A;  4JE4 A;  3PJP A;  4DGP A;  1LUK A;  3WA4 A;  4P9V A;  1BMB A;  1LUM A;  3VRQ A;  1CWD L;  4OHI A;  2Y1N A;  1BFJ A;  2PLE A;  1LKL A;  5IBS A;  1O45 A;  3VS1 A;  1WQU A;  3HHM B;  1KC2 A;  1O4F A;  3HCK A;  4OHE A;  2MK2 A;  2H5K A;  1O4G A;  2EO3 A;  2GSB A;  1BM2 A;  1O4O A;  3BUW B;  3C7I A;  3UYO A;  1IS0 A;  1O4N A;  2Y1M A;  3M7F A;  3MAZ A;  3TL0 A;  2H46 E;  2SRC A;  1O42 A;  3IMJ A;  3K2M A;  1A1B A;  2PNA A;  1O4H A;  2DM0 A;  3QWY A;  2EL8 A;  1FBZ A;  2DX0 A;  2RVF A;  1A1C A;  1R1Q A;  2DLY A;  5J3X A;  1O4I A;  1JU5 A;  5AUL A;  3KFJ A;  5EHR A;  3S9K A;  4OHH A;  4GL9 E;  2H8H A;  2HUW A;  1O4Q A;  1AYB A;  2GE9 A;  4FL3 A;  2JYQ A;  1LUI A;  2ROR A;  5DC9 A;  1O4A A;  1O41 A;  1X27 A;  1UUR A;  1TZE E;  1FU6 A;  2C0O A;  1H9O A;  1O48 A;  4M4Z A;  4DGX A;  3N84 A;  5HKY A;  1LKK A;  1MW4 A;  1O4L A;  2MRJ A;  2PLD A;  1O4C A;  1O49 A;  1SPR A;  1O44 A;  3GXX A;  1OO4 A;  1CWE A;  3OV1 A;  3IN8 A;  1QAD A;  1I3Z A;  4F5A A;  3VRZ A;  1GHU A;  1D4W A;  3CBL A;  3CXL A;  1QG1 E;  1K9A A;  3HIZ B;  1PIC A;  5GJI A;  3PSJ A;  1NRV A;  2C0T A;  3EAZ A;  2MC1 A;  2C9W A;  3VRR A;  1RJA A;  2CR4 A;  1IJR A;  3ZNI A;  1P13 A;  4K44 A;  4EIH A;  1B47 A;  1RQQ C;  3BUX B;  1HCT B;  3VRN A;  1KA6 A;  4EY0 A;  1FHS A;  1SHA A;  2CIA A;  5AXI A;  3VRO A;  1MIL A;  4XZ1 A;  5HKZ A;  1AOT F;  1BFI A;  3VRY A;  3IN7 A;  3VS7 A;  1BF5 A;  1Y57 A;  1O4B A;  1JWO A;  1NZL A;  1O4P A;  1SPS A;  2HCK A;  4E93 A;  1TCE A;  1BLK A;  1O4R A;  1SKJ A;  5EEQ A;  1R1P A;  1NZV A;  1JYQ A;  2SHP A;  4A4C A;  2YSX A;  5EG3 B;  3PFV A;  5CDW A;  4F5B A;  1Y1U A;  5DF6 A;  2LNW A;  3VS0 A;  1BLJ A;  2DCR A;  3VGO A;  2EO6 A;  3BUO B;  1UUS A;  3N8M A; 
#chains in the Genus database with same CATH topology
 1OO3 A;  3MXY A;  5DC0 B;  1BKL A;  2VIF A;  2EYV A;  1A07 A;  1JYU A;  2MQI A;  2IUG A;  5GJH A;  3PSK A;  2EYY A;  1FYR A;  2K79 B;  4U17 A;  1JYR A;  2LCT A;  2AOA A;  2RSY A;  1HCS B;  1CJ1 A;  5HKW A;  1QCF A;  5EHP A;  1A09 A;  1AB2 A;  4XZ0 A;  2LQW A;  1AYC A;  4NWG A;  3VRP A;  1M27 A;  4JGH A;  3OB1 B;  3GQI B;  3VS4 A;  3T04 A;  1AYD A;  1OPK A;  5I6V A;  1D1Z A;  3VS5 A;  1O46 A;  2PTK A;  1Z3K A;  4E68 A;  4ROJ A;  1F1W A;  1YVH A;  2FCI A;  2CI8 A;  3BUM B;  2MRK A;  1O4E A;  2L6K A;  1YVL A;  1SHD A;  3S8N A;  2HMH A;  5KAZ A;  5D0J A;  1KA7 A;  5IBM A;  1BG1 A;  2CI9 A;  2L4K A;  2XP1 A;  5EEL A;  1O4D A;  1A1E A;  1CSY A;  4GWF A;  2FO0 A;  2AOB A;  3NHN A;  4K2R A;  2IUI A;  2YU7 A;  2EOB A;  3EAC A;  1D4T A;  1A08 A;  3GXW A;  3QWX X;  2DLZ A;  4H34 A;  1A1A A;  1OPL A;  3MXC A;  1FU5 A;  2CRH A;  2RMX A;  3PLF B;  2HDX A;  1GRI A;  1AYA A;  1BHH A;  2ABL A;  1O4M A;  3OVE A;  2HDV A;  2EU0 A;  4QSY A;  2IZV A;  3BKB A;  2DVJ A;  4FL2 A;  4K45 A;  2L3T A;  2EKX A;  2Y3A B;  1LCK A;  2C0I A;  4P9Z A;  4K11 A;  2ECD A;  3N7Y A;  4LUE A;  1AD5 A;  4NWF A;  1O47 A;  3S8O A;  4LUD A;  2OQ1 A;  1CSZ A;  1FBV A;  3PQZ A;  4FBN A;  3IMD A;  1M61 A;  3VS2 A;  2CS0 A;  1RPY A;  1F2F A;  1BHH B;  4D8K A;  3CD3 A;  4H1O A;  2CBL A;  1LCJ A;  4X6S A;  1KSW A;  3CWG A;  2OZO A;  1X6C A;  1ZFP E;  2IUH A;  4WWQ A;  5BO4 A;  1R1S A;  1X0N A;  2KNO A;  3UF4 A;  3VS3 A;  2BBU A;  2LQN A;  4F59 A;  2EYZ A;  3US4 A;  1AOU F;  2QMS A;  3PS5 A;  4L1B B;  4A4B A;  2PNB A;  4JEG A;  3S8L A;  2KK6 A;  2AUG A;  3BUN B;  1BKM A;  3OP0 A;  5DC4 A;  1FMK A;  3VS6 A;  1BHF A;  4GPL B;  2K7A B;  4OHL A;  3TKZ A;  2LNX A;  2ETZ A;  1G83 A;  4TZI A;  2B3O A;  1O4K A;  1XA6 A;  4OHD A;  4U1P A;  1LUN A;  1SHB A;  1A81 A;  1O43 A;  3OB2 B;  1O4J A;  4JE4 A;  3PJP A;  4DGP A;  1LUK A;  3WA4 A;  4P9V A;  1BMB A;  1LUM A;  3VRQ A;  1CWD L;  4OHI A;  2Y1N A;  1BFJ A;  2PLE A;  1LKL A;  5IBS A;  1O45 A;  3VS1 A;  1WQU A;  3HHM B;  1KC2 A;  1O4F A;  3HCK A;  4OHE A;  2MK2 A;  2H5K A;  1O4G A;  2EO3 A;  2GSB A;  1BM2 A;  1O4O A;  3BUW B;  3C7I A;  3UYO A;  1IS0 A;  1O4N A;  2Y1M A;  3M7F A;  3MAZ A;  3TL0 A;  2H46 E;  2SRC A;  1O42 A;  3IMJ A;  3K2M A;  1A1B A;  2PNA A;  1O4H A;  2DM0 A;  3QWY A;  2EL8 A;  1FBZ A;  3LYV A;  2DX0 A;  2RVF A;  1A1C A;  1R1Q A;  2DLY A;  5J3X A;  1O4I A;  1JU5 A;  5AUL A;  3KFJ A;  5EHR A;  3S9K A;  4OHH A;  4GL9 E;  2H8H A;  2HUW A;  1O4Q A;  1AYB A;  2GE9 A;  4FL3 A;  2JYQ A;  1LUI A;  2ROR A;  5DC9 A;  1O4A A;  1O41 A;  1X27 A;  1UUR A;  1TZE E;  1FU6 A;  2C0O A;  1H9O A;  1O48 A;  4M4Z A;  4DGX A;  3N84 A;  5HKY A;  1LKK A;  1MW4 A;  1O4L A;  2MRJ A;  2PLD A;  1O4C A;  1O49 A;  1SPR A;  1O44 A;  3GXX A;  1OO4 A;  1CWE A;  3OV1 A;  3IN8 A;  1QAD A;  1I3Z A;  4F5A A;  3VRZ A;  1GHU A;  1D4W A;  3CBL A;  3CXL A;  1QG1 E;  1K9A A;  3HIZ B;  2KGY A;  1PIC A;  5GJI A;  3PSJ A;  1NRV A;  2C0T A;  3EAZ A;  2MC1 A;  2C9W A;  3VRR A;  1RJA A;  2CR4 A;  1IJR A;  3ZNI A;  3K2T A;  1P13 A;  4K44 A;  4EIH A;  1B47 A;  1RQQ C;  3BUX B;  1HCT B;  3VRN A;  1KA6 A;  4EY0 A;  1FHS A;  1SHA A;  2CIA A;  5AXI A;  3VRO A;  1MIL A;  4XZ1 A;  5HKZ A;  1AOT F;  1BFI A;  3VRY A;  3IN7 A;  3VS7 A;  1BF5 A;  1Y57 A;  1O4B A;  1JWO A;  2LRA A;  1NZL A;  1O4P A;  1SPS A;  2HCK A;  4E93 A;  1TCE A;  1BLK A;  1O4R A;  1SKJ A;  5EEQ A;  1R1P A;  1NZV A;  1JYQ A;  2SHP A;  4A4C A;  2YSX A;  5EG3 B;  3PFV A;  5CDW A;  4F5B A;  1Y1U A;  5DF6 A;  2LNW A;  3VS0 A;  1BLJ A;  2DCR A;  3VGO A;  2EO6 A;  3BUO B;  1UUS A;  3N8M A; 
#chains in the Genus database with same CATH homology
 1OO3 A;  3MXY A;  5DC0 B;  1BKL A;  2VIF A;  2EYV A;  1A07 A;  1JYU A;  2MQI A;  2IUG A;  5GJH A;  3PSK A;  2EYY A;  1FYR A;  2K79 B;  4U17 A;  1JYR A;  2LCT A;  2AOA A;  2RSY A;  1HCS B;  1CJ1 A;  5HKW A;  1QCF A;  5EHP A;  1A09 A;  1AB2 A;  4XZ0 A;  2LQW A;  1AYC A;  4NWG A;  3VRP A;  1M27 A;  4JGH A;  3OB1 B;  3GQI B;  3VS4 A;  3T04 A;  1AYD A;  1OPK A;  5I6V A;  1D1Z A;  3VS5 A;  1O46 A;  2PTK A;  1Z3K A;  4E68 A;  4ROJ A;  1F1W A;  1YVH A;  2FCI A;  2CI8 A;  3BUM B;  2MRK A;  1O4E A;  2L6K A;  1YVL A;  1SHD A;  3S8N A;  2HMH A;  5KAZ A;  5D0J A;  1KA7 A;  5IBM A;  1BG1 A;  2CI9 A;  2L4K A;  2XP1 A;  5EEL A;  1O4D A;  1A1E A;  1CSY A;  4GWF A;  2FO0 A;  2AOB A;  3NHN A;  4K2R A;  2IUI A;  2YU7 A;  2EOB A;  3EAC A;  1D4T A;  1A08 A;  3GXW A;  3QWX X;  2DLZ A;  4H34 A;  1A1A A;  1OPL A;  3MXC A;  1FU5 A;  2CRH A;  2RMX A;  3PLF B;  2HDX A;  1GRI A;  1AYA A;  1BHH A;  2ABL A;  1O4M A;  3OVE A;  2HDV A;  2EU0 A;  4QSY A;  2IZV A;  3BKB A;  2DVJ A;  4FL2 A;  4K45 A;  2L3T A;  2EKX A;  2Y3A B;  1LCK A;  2C0I A;  4P9Z A;  4K11 A;  2ECD A;  3N7Y A;  4LUE A;  1AD5 A;  4NWF A;  1O47 A;  3S8O A;  4LUD A;  2OQ1 A;  1CSZ A;  1FBV A;  3PQZ A;  4FBN A;  3IMD A;  1M61 A;  3VS2 A;  2CS0 A;  1RPY A;  1F2F A;  1BHH B;  4D8K A;  3CD3 A;  4H1O A;  2CBL A;  1LCJ A;  4X6S A;  1KSW A;  3CWG A;  2OZO A;  1X6C A;  1ZFP E;  2IUH A;  4WWQ A;  5BO4 A;  1R1S A;  1X0N A;  2KNO A;  3UF4 A;  3VS3 A;  2BBU A;  2LQN A;  4F59 A;  2EYZ A;  3US4 A;  1AOU F;  2QMS A;  3PS5 A;  4L1B B;  4A4B A;  2PNB A;  4JEG A;  3S8L A;  2KK6 A;  2AUG A;  3BUN B;  1BKM A;  3OP0 A;  5DC4 A;  1FMK A;  3VS6 A;  1BHF A;  4GPL B;  2K7A B;  4OHL A;  3TKZ A;  2LNX A;  2ETZ A;  1G83 A;  4TZI A;  2B3O A;  1O4K A;  1XA6 A;  4OHD A;  4U1P A;  1LUN A;  1SHB A;  1A81 A;  1O43 A;  3OB2 B;  1O4J A;  4JE4 A;  3PJP A;  4DGP A;  1LUK A;  3WA4 A;  4P9V A;  1BMB A;  1LUM A;  3VRQ A;  1CWD L;  4OHI A;  2Y1N A;  1BFJ A;  2PLE A;  1LKL A;  5IBS A;  1O45 A;  3VS1 A;  1WQU A;  3HHM B;  1KC2 A;  1O4F A;  3HCK A;  4OHE A;  2MK2 A;  2H5K A;  1O4G A;  2EO3 A;  2GSB A;  1BM2 A;  1O4O A;  3BUW B;  3C7I A;  3UYO A;  1IS0 A;  1O4N A;  2Y1M A;  3M7F A;  3MAZ A;  3TL0 A;  2H46 E;  2SRC A;  1O42 A;  3IMJ A;  3K2M A;  1A1B A;  2PNA A;  1O4H A;  2DM0 A;  3QWY A;  2EL8 A;  1FBZ A;  2DX0 A;  2RVF A;  1A1C A;  1R1Q A;  2DLY A;  5J3X A;  1O4I A;  1JU5 A;  5AUL A;  3KFJ A;  5EHR A;  3S9K A;  4OHH A;  4GL9 E;  2H8H A;  2HUW A;  1O4Q A;  1AYB A;  2GE9 A;  4FL3 A;  2JYQ A;  1LUI A;  2ROR A;  5DC9 A;  1O4A A;  1O41 A;  1X27 A;  1UUR A;  1TZE E;  1FU6 A;  2C0O A;  1H9O A;  1O48 A;  4M4Z A;  4DGX A;  3N84 A;  5HKY A;  1LKK A;  1MW4 A;  1O4L A;  2MRJ A;  2PLD A;  1O4C A;  1O49 A;  1SPR A;  1O44 A;  3GXX A;  1OO4 A;  1CWE A;  3OV1 A;  3IN8 A;  1QAD A;  1I3Z A;  4F5A A;  3VRZ A;  1GHU A;  1D4W A;  3CBL A;  3CXL A;  1QG1 E;  1K9A A;  3HIZ B;  1PIC A;  5GJI A;  3PSJ A;  1NRV A;  2C0T A;  3EAZ A;  2MC1 A;  2C9W A;  3VRR A;  1RJA A;  2CR4 A;  1IJR A;  3ZNI A;  1P13 A;  4K44 A;  4EIH A;  1B47 A;  1RQQ C;  3BUX B;  1HCT B;  3VRN A;  1KA6 A;  4EY0 A;  1FHS A;  1SHA A;  2CIA A;  5AXI A;  3VRO A;  1MIL A;  4XZ1 A;  5HKZ A;  1AOT F;  1BFI A;  3VRY A;  3IN7 A;  3VS7 A;  1BF5 A;  1Y57 A;  1O4B A;  1JWO A;  1NZL A;  1O4P A;  1SPS A;  2HCK A;  4E93 A;  1TCE A;  1BLK A;  1O4R A;  1SKJ A;  5EEQ A;  1R1P A;  1NZV A;  1JYQ A;  2SHP A;  4A4C A;  2YSX A;  5EG3 B;  3PFV A;  5CDW A;  4F5B A;  1Y1U A;  5DF6 A;  2LNW A;  3VS0 A;  1BLJ A;  2DCR A;  3VGO A;  2EO6 A;  3BUO B;  1UUS A;  3N8M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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