1O4FA

Crystal structure of sh2 in complex with ru79073.
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
105
structure length
104
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 25
structure length 104
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4fA00
3VRYA 5DC0B 2Y1NA 2RVFA 1LUIA 1O4JA 1O4NA 2DVJA 2DLZA 2RORA 3C7IA 4FBNA 2YU7A 1H9OA 5BO4A 1MILA 2AUGA 4LUEA 3TKZA 1BM2A 1FYRA 1BHHA 2GE9A 1FU5A 3VS3A 4JEGA 5GJIA 2LQNA 1HCTB 3N84A 2CIAA 3IMDA 2EYVA 1O41A 1BHHB 1B47A 5J3XA 3GQIB 1O4OA 3VS1A 5DC9A 1PICA 3K2MA 1X6CA 3HIZB 3ZNIA 2GSBA 2L6KA 4NWFA 3US4A 1GHUA 2HDXA 1RPYA 2EU0A 1CSYA 4K45A 2DM0A 4K11A 4FL2A 2EOBA 2QMSA 1QG1E 2CRHA 1O4KA 1LKLA 2AOBA 1Y57A 5EELA 1ZFPE 2LNWA 2XP1A 1JYUA 1O4BA 2PLEA 1QCFA 4U17A 5IBSA 3GXWA 1AOUF 3QWYA 2C9WA 3T04A 5AULA 1OO3A 1TCEA 1SKJA 3GXXA 1D4TA 5I6VA 3VS7A 3CWGA 4FL3A 1O4FA 1AYBA 2FO0A 4JGHA 1O4GA 1SHDA 1CWDL 1NRVA 1Y1UA 2C0TA 3MXCA 2PLDA 3N8MA 1A09A 1A08A 4DGXA 4F59A 3OB2B 2OZOA 1A1BA 1SPRA 3OB1B 1O42A 1O4LA 1O45A 2LNXA 4LUDA 1HCSB 1A1AA 2MK2A 3OP0A 1F2FA 3IN7A 1KSWA 4EIHA 2SHPA 4A4CA 1LKKA 1I3ZA 1QADA 2EL8A 2CI9A 2EO3A 3VS2A 2KK6A 3VS0A 1F1WA 4K2RA 3VS5A 1BMBA 3QWXX 1XA6A 3KFJA 1O4IA 1GRIA 3BUNB 4GL9E 4EY0A 2KNOA 2AOAA 5CDWA 3VS6A 2MRJA 1CWEA 3PQZA 2PNAA 1G83A 1X0NA 2CI8A 4H1OA 3S8OA 1O4HA 1SPSA 2MC1A 1O44A 3PSKA 2HCKA 4P9VA 1WQUA 1BLJA 4F5BA 2MRKA 1AB2A 2H5KA 4L1BB 5IBMA 2IUIA 1OPLA 1O4PA 5D0JA 1O4DA 2HDVA 4K44A 1O4MA 3HHMB 4F5AA 2H46E 1KA6A 2HUWA 2L3TA 2K7AB 3M7FA 3MXYA 5AXIA 3OVEA 3S9KA 3PJPA 1O4QA 2ABLA 3UF4A 1P13A 1R1QA 1KC2A 1IS0A 1O43A 2SRCA 2MQIA 3IMJA 1LUMA 4XZ1A 2PNBA 3EAZA 4JE4A 3VGOA 2VIFA 3BUOB 2CR4A 2HMHA 3PSJA 3VRZA 5EEQA 2C0OA 2EYYA 2ECDA 1CJ1A 4TZIA 5HKYA 1O4CA 3UYOA 1AOTF 2YSXA 4OHEA 5EG3B 2EKXA 1SHBA 1A1CA 1AYCA 1O46A 1BF5A 2K79B 2IUGA 2Y1MA 4H34A 1FU6A 4U1PA 1O49A 4E68A 4QSYA 2ETZA 3VRPA 1O4AA 2H8HA 2IZVA 3PS5A 2RMXA 1O4EA 3VRRA 1BHFA 2RSYA 1FBZA 4OHLA 4OHHA 1BFIA 5EHRA 2PTKA 1TZEE 1NZVA 3BUMB 1BFJA 3WA4A 5KAZA 4M4ZA 1SHAA 4DGPA 1RJAA 1LCJA 3VS4A 2C0IA 1OPKA 1YVHA 2CBLA 1K9AA 1FBVA 2CS0A 5HKZA 2L4KA 2DX0A 3CXLA 2LCTA 3BUXB 3HCKA 1AYDA 2B3OA 1UURA 2EO6A 1LCKA 3VRQA 4NWGA 1JU5A 3BUWB 3BKBA 4XZ0A 5GJHA 1A81A 4X6SA 3OV1A 1JWOA 1AD5A 1M61A 4OHDA 1O48A 5HKWA 4P9ZA 3VRNA 2JYQA 1FHSA 1MW4A 4GPLB 2DLYA 2BBUA 1OO4A 5DF6A 1CSZA 3S8NA 1FMKA 3PFVA 1LUKA 3N7YA 2FCIA 3IN8A 1X27A 1RQQC 3NHNA 2LQWA 2Y3AB 3CD3A 2DCRA 5DC4A 1JYRA 3VROA 3TL0A 2OQ1A 1R1SA 1D4WA 4OHIA 1BKMA 4A4BA 5EHPA 2EYZA 1KA7A 1A1EA 1D1ZA 4D8KA 3PLFB 1JYQA 1A07A 4WWQA 1IJRA 1LUNA 1YVLA 1BLKA 1M27A 3EACA 1O47A 2IUHA 4GWFA 4ROJA 1BKLA 1O4RA 3S8LA 1UUSA 1Z3KA 3MAZA 4E93A 1NZLA 3CBLA 1BG1A 1R1PA 1AYAA
chains in the Genus database with same CATH superfamily
3VRYA 5DC0B 2Y1NA 2RVFA 1LUIA 1O4JA 1O4NA 2DVJA 2DLZA 2RORA 3C7IA 4FBNA 2YU7A 1H9OA 5BO4A 1MILA 2AUGA 4LUEA 3TKZA 1BM2A 1FYRA 1BHHA 2GE9A 1FU5A 3VS3A 4JEGA 5GJIA 2LQNA 1HCTB 3N84A 2CIAA 3IMDA 2EYVA 1O41A 1BHHB 1B47A 5J3XA 3GQIB 1O4OA 3VS1A 5DC9A 1PICA 3K2MA 1X6CA 3HIZB 3ZNIA 2GSBA 2L6KA 4NWFA 3US4A 1GHUA 2HDXA 1RPYA 2EU0A 1CSYA 4K45A 2DM0A 4K11A 4FL2A 2EOBA 2QMSA 1QG1E 2CRHA 1O4KA 1LKLA 2AOBA 1Y57A 5EELA 1ZFPE 2LNWA 2XP1A 1JYUA 1O4BA 2PLEA 1QCFA 4U17A 5IBSA 3GXWA 1AOUF 3QWYA 2C9WA 3T04A 5AULA 1OO3A 1TCEA 1SKJA 3GXXA 1D4TA 5I6VA 3VS7A 3CWGA 4FL3A 1O4FA 1AYBA 2FO0A 4JGHA 1O4GA 1SHDA 1CWDL 1NRVA 1Y1UA 2C0TA 3MXCA 2PLDA 3N8MA 1A09A 1A08A 4DGXA 4F59A 3OB2B 2OZOA 1A1BA 1SPRA 3OB1B 1O42A 1O4LA 1O45A 2LNXA 4LUDA 1HCSB 1A1AA 2MK2A 3OP0A 1F2FA 3IN7A 1KSWA 4EIHA 2SHPA 4A4CA 1LKKA 3LYVA 1I3ZA 1QADA 2EL8A 2CI9A 2EO3A 3VS2A 2KK6A 3VS0A 1F1WA 4K2RA 3VS5A 1BMBA 3QWXX 1XA6A 3KFJA 1O4IA 1GRIA 3BUNB 4GL9E 4EY0A 2KNOA 2AOAA 5CDWA 3VS6A 2MRJA 1CWEA 3PQZA 2PNAA 1G83A 1X0NA 2CI8A 4H1OA 3S8OA 1O4HA 1SPSA 2MC1A 1O44A 3PSKA 2HCKA 4P9VA 1WQUA 1BLJA 4F5BA 2MRKA 1AB2A 2H5KA 4L1BB 5IBMA 2IUIA 1OPLA 1O4PA 5D0JA 1O4DA 2HDVA 4K44A 1O4MA 3HHMB 4F5AA 2H46E 1KA6A 2HUWA 2L3TA 2K7AB 3M7FA 3MXYA 5AXIA 3OVEA 3S9KA 3PJPA 1O4QA 2ABLA 3UF4A 1P13A 1R1QA 1KC2A 1IS0A 1O43A 2SRCA 2MQIA 3IMJA 1LUMA 4XZ1A 2PNBA 2KGYA 3EAZA 4JE4A 3VGOA 2VIFA 3BUOB 2CR4A 2HMHA 3PSJA 3VRZA 5EEQA 2C0OA 2EYYA 2ECDA 1CJ1A 4TZIA 5HKYA 1O4CA 3UYOA 1AOTF 2YSXA 4OHEA 5EG3B 2EKXA 1SHBA 1A1CA 1AYCA 1O46A 1BF5A 2K79B 2IUGA 2Y1MA 4H34A 1FU6A 4U1PA 1O49A 4E68A 4QSYA 2ETZA 3VRPA 1O4AA 2H8HA 2IZVA 3PS5A 2RMXA 1O4EA 3VRRA 1BHFA 2RSYA 1FBZA 4OHLA 4OHHA 1BFIA 5EHRA 2PTKA 1TZEE 1NZVA 3BUMB 1BFJA 3WA4A 5KAZA 4M4ZA 1SHAA 4DGPA 1RJAA 1LCJA 3VS4A 2C0IA 1OPKA 1YVHA 2CBLA 1K9AA 1FBVA 2CS0A 5HKZA 2L4KA 2DX0A 3CXLA 2LCTA 3BUXB 3HCKA 1AYDA 2B3OA 2LRAA 1UURA 2EO6A 1LCKA 3VRQA 4NWGA 1JU5A 3BUWB 3BKBA 4XZ0A 5GJHA 1A81A 4X6SA 3OV1A 1JWOA 1AD5A 1M61A 4OHDA 1O48A 3K2TA 5HKWA 4P9ZA 3VRNA 2JYQA 1FHSA 1MW4A 4GPLB 2DLYA 2BBUA 1OO4A 5DF6A 1CSZA 3S8NA 1FMKA 3PFVA 1LUKA 3N7YA 2FCIA 3IN8A 1X27A 1RQQC 3NHNA 2LQWA 2Y3AB 3CD3A 2DCRA 5DC4A 1JYRA 3VROA 3TL0A 2OQ1A 1R1SA 1D4WA 4OHIA 1BKMA 4A4BA 5EHPA 2EYZA 1KA7A 1A1EA 1D1ZA 4D8KA 3PLFB 1JYQA 1A07A 4WWQA 1IJRA 1LUNA 1YVLA 1BLKA 1M27A 3EACA 1O47A 2IUHA 4GWFA 4ROJA 1BKLA 1O4RA 3S8LA 1UUSA 1Z3KA 3MAZA 4E93A 1NZLA 3CBLA 1BG1A 1R1PA 1AYAA
chains in the Genus database with same CATH topology
3VRYA 5DC0B 2Y1NA 2RVFA 1LUIA 1O4JA 1O4NA 2DVJA 2DLZA 2RORA 3C7IA 4FBNA 2YU7A 1H9OA 5BO4A 1MILA 2AUGA 4LUEA 3TKZA 1BM2A 1FYRA 1BHHA 2GE9A 1FU5A 3VS3A 4JEGA 5GJIA 2LQNA 1HCTB 3N84A 2CIAA 3IMDA 2EYVA 1O41A 1BHHB 1B47A 5J3XA 3GQIB 1O4OA 3VS1A 5DC9A 1PICA 3K2MA 1X6CA 3HIZB 3ZNIA 2GSBA 2L6KA 4NWFA 3US4A 1GHUA 2HDXA 1RPYA 2EU0A 1CSYA 4K45A 2DM0A 4K11A 4FL2A 2EOBA 2QMSA 1QG1E 2CRHA 1O4KA 1LKLA 2AOBA 1Y57A 5EELA 1ZFPE 2LNWA 2XP1A 1JYUA 1O4BA 2PLEA 1QCFA 4U17A 5IBSA 3GXWA 1AOUF 3QWYA 2C9WA 3T04A 5AULA 1OO3A 1TCEA 1SKJA 3GXXA 1D4TA 5I6VA 3VS7A 3CWGA 4FL3A 1O4FA 1AYBA 2FO0A 4JGHA 1O4GA 1SHDA 1CWDL 1NRVA 1Y1UA 2C0TA 3MXCA 2PLDA 3N8MA 1A09A 1A08A 4DGXA 4F59A 3OB2B 2OZOA 1A1BA 1SPRA 3OB1B 1O42A 1O4LA 1O45A 2LNXA 4LUDA 1HCSB 1A1AA 2MK2A 3OP0A 1F2FA 3IN7A 1KSWA 4EIHA 2SHPA 4A4CA 1LKKA 1I3ZA 1QADA 2EL8A 2CI9A 2EO3A 3VS2A 2KK6A 3VS0A 1F1WA 4K2RA 3VS5A 1BMBA 3QWXX 1XA6A 3KFJA 1O4IA 1GRIA 3BUNB 4GL9E 4EY0A 2KNOA 2AOAA 5CDWA 3VS6A 2MRJA 1CWEA 3PQZA 2PNAA 1G83A 1X0NA 2CI8A 4H1OA 3S8OA 1O4HA 1SPSA 2MC1A 1O44A 3PSKA 2HCKA 4P9VA 1WQUA 1BLJA 4F5BA 2MRKA 1AB2A 2H5KA 4L1BB 5IBMA 2IUIA 1OPLA 1O4PA 5D0JA 1O4DA 2HDVA 4K44A 1O4MA 3HHMB 4F5AA 2H46E 1KA6A 2HUWA 2L3TA 2K7AB 3M7FA 3MXYA 5AXIA 3OVEA 3S9KA 3PJPA 1O4QA 2ABLA 3UF4A 1P13A 1R1QA 1KC2A 1IS0A 1O43A 2SRCA 2MQIA 3IMJA 1LUMA 4XZ1A 2PNBA 3EAZA 4JE4A 3VGOA 2VIFA 3BUOB 2CR4A 2HMHA 3PSJA 3VRZA 5EEQA 2C0OA 2EYYA 2ECDA 1CJ1A 4TZIA 5HKYA 1O4CA 3UYOA 1AOTF 2YSXA 4OHEA 5EG3B 2EKXA 1SHBA 1A1CA 1AYCA 1O46A 1BF5A 2K79B 2IUGA 2Y1MA 4H34A 1FU6A 4U1PA 1O49A 4E68A 4QSYA 2ETZA 3VRPA 1O4AA 2H8HA 2IZVA 3PS5A 2RMXA 1O4EA 3VRRA 1BHFA 2RSYA 1FBZA 4OHLA 4OHHA 1BFIA 5EHRA 2PTKA 1TZEE 1NZVA 3BUMB 1BFJA 3WA4A 5KAZA 4M4ZA 1SHAA 4DGPA 1RJAA 1LCJA 3VS4A 2C0IA 1OPKA 1YVHA 2CBLA 1K9AA 1FBVA 2CS0A 5HKZA 2L4KA 2DX0A 3CXLA 2LCTA 3BUXB 3HCKA 1AYDA 2B3OA 1UURA 2EO6A 1LCKA 3VRQA 4NWGA 1JU5A 3BUWB 3BKBA 4XZ0A 5GJHA 1A81A 4X6SA 3OV1A 1JWOA 1AD5A 1M61A 4OHDA 1O48A 5HKWA 4P9ZA 3VRNA 2JYQA 1FHSA 1MW4A 4GPLB 2DLYA 2BBUA 1OO4A 5DF6A 1CSZA 3S8NA 1FMKA 3PFVA 1LUKA 3N7YA 2FCIA 3IN8A 1X27A 1RQQC 3NHNA 2LQWA 2Y3AB 3CD3A 2DCRA 5DC4A 1JYRA 3VROA 3TL0A 2OQ1A 1R1SA 1D4WA 4OHIA 1BKMA 4A4BA 5EHPA 2EYZA 1KA7A 1A1EA 1D1ZA 4D8KA 3PLFB 1JYQA 1A07A 4WWQA 1IJRA 1LUNA 1YVLA 1BLKA 1M27A 3EACA 1O47A 2IUHA 4GWFA 4ROJA 1BKLA 1O4RA 3S8LA 1UUSA 1Z3KA 3MAZA 4E93A 1NZLA 3CBLA 1BG1A 1R1PA 1AYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VRY A;  5DC0 B;  2Y1N A;  2RVF A;  1LUI A;  1O4J A;  1O4N A;  2DVJ A;  2DLZ A;  2ROR A;  3C7I A;  4FBN A;  2YU7 A;  1H9O A;  5BO4 A;  1MIL A;  2AUG A;  4LUE A;  3TKZ A;  1BM2 A;  1FYR A;  1BHH A;  2GE9 A;  1FU5 A;  3VS3 A;  4JEG A;  5GJI A;  2LQN A;  1HCT B;  3N84 A;  2CIA A;  3IMD A;  2EYV A;  1O41 A;  1BHH B;  1B47 A;  5J3X A;  3GQI B;  1O4O A;  3VS1 A;  5DC9 A;  1PIC A;  3K2M A;  1X6C A;  3HIZ B;  3ZNI A;  2GSB A;  2L6K A;  4NWF A;  3US4 A;  1GHU A;  2HDX A;  1RPY A;  2EU0 A;  1CSY A;  4K45 A;  2DM0 A;  4K11 A;  4FL2 A;  2EOB A;  2QMS A;  1QG1 E;  2CRH A;  1O4K A;  1LKL A;  2AOB A;  1Y57 A;  5EEL A;  1ZFP E;  2LNW A;  2XP1 A;  1JYU A;  1O4B A;  2PLE A;  1QCF A;  4U17 A;  5IBS A;  3GXW A;  1AOU F;  3QWY A;  2C9W A;  3T04 A;  5AUL A;  1OO3 A;  1TCE A;  1SKJ A;  3GXX A;  1D4T A;  5I6V A;  3VS7 A;  3CWG A;  4FL3 A;  1O4F A;  1AYB A;  2FO0 A;  4JGH A;  1O4G A;  1SHD A;  1CWD L;  1NRV A;  1Y1U A;  2C0T A;  3MXC A;  2PLD A;  3N8M A;  1A09 A;  1A08 A;  4DGX A;  4F59 A;  3OB2 B;  2OZO A;  1A1B A;  1SPR A;  3OB1 B;  1O42 A;  1O4L A;  1O45 A;  2LNX A;  4LUD A;  1HCS B;  1A1A A;  2MK2 A;  3OP0 A;  1F2F A;  3IN7 A;  1KSW A;  4EIH A;  2SHP A;  4A4C A;  1LKK A;  1I3Z A;  1QAD A;  2EL8 A;  2CI9 A;  2EO3 A;  3VS2 A;  2KK6 A;  3VS0 A;  1F1W A;  4K2R A;  3VS5 A;  1BMB A;  3QWX X;  1XA6 A;  3KFJ A;  1O4I A;  1GRI A;  3BUN B;  4GL9 E;  4EY0 A;  2KNO A;  2AOA A;  5CDW A;  3VS6 A;  2MRJ A;  1CWE A;  3PQZ A;  2PNA A;  1G83 A;  1X0N A;  2CI8 A;  4H1O A;  3S8O A;  1O4H A;  1SPS A;  2MC1 A;  1O44 A;  3PSK A;  2HCK A;  4P9V A;  1WQU A;  1BLJ A;  4F5B A;  2MRK A;  1AB2 A;  2H5K A;  4L1B B;  5IBM A;  2IUI A;  1OPL A;  1O4P A;  5D0J A;  1O4D A;  2HDV A;  4K44 A;  1O4M A;  3HHM B;  4F5A A;  2H46 E;  1KA6 A;  2HUW A;  2L3T A;  2K7A B;  3M7F A;  3MXY A;  5AXI A;  3OVE A;  3S9K A;  3PJP A;  1O4Q A;  2ABL A;  3UF4 A;  1P13 A;  1R1Q A;  1KC2 A;  1IS0 A;  1O43 A;  2SRC A;  2MQI A;  3IMJ A;  1LUM A;  4XZ1 A;  2PNB A;  3EAZ A;  4JE4 A;  3VGO A;  2VIF A;  3BUO B;  2CR4 A;  2HMH A;  3PSJ A;  3VRZ A;  5EEQ A;  2C0O A;  2EYY A;  2ECD A;  1CJ1 A;  4TZI A;  5HKY A;  1O4C A;  3UYO A;  1AOT F;  2YSX A;  4OHE A;  5EG3 B;  2EKX A;  1SHB A;  1A1C A;  1AYC A;  1O46 A;  1BF5 A;  2K79 B;  2IUG A;  2Y1M A;  4H34 A;  1FU6 A;  4U1P A;  1O49 A;  4E68 A;  4QSY A;  2ETZ A;  3VRP A;  1O4A A;  2H8H A;  2IZV A;  3PS5 A;  2RMX A;  1O4E A;  3VRR A;  1BHF A;  2RSY A;  1FBZ A;  4OHL A;  4OHH A;  1BFI A;  5EHR A;  2PTK A;  1TZE E;  1NZV A;  3BUM B;  1BFJ A;  3WA4 A;  5KAZ A;  4M4Z A;  1SHA A;  4DGP A;  1RJA A;  1LCJ A;  3VS4 A;  2C0I A;  1OPK A;  1YVH A;  2CBL A;  1K9A A;  1FBV A;  2CS0 A;  5HKZ A;  2L4K A;  2DX0 A;  3CXL A;  2LCT A;  3BUX B;  3HCK A;  1AYD A;  2B3O A;  1UUR A;  2EO6 A;  1LCK A;  3VRQ A;  4NWG A;  1JU5 A;  3BUW B;  3BKB A;  4XZ0 A;  5GJH A;  1A81 A;  4X6S A;  3OV1 A;  1JWO A;  1AD5 A;  1M61 A;  4OHD A;  1O48 A;  5HKW A;  4P9Z A;  3VRN A;  2JYQ A;  1FHS A;  1MW4 A;  4GPL B;  2DLY A;  2BBU A;  1OO4 A;  5DF6 A;  1CSZ A;  3S8N A;  1FMK A;  3PFV A;  1LUK A;  3N7Y A;  2FCI A;  3IN8 A;  1X27 A;  1RQQ C;  3NHN A;  2LQW A;  2Y3A B;  3CD3 A;  2DCR A;  5DC4 A;  1JYR A;  3VRO A;  3TL0 A;  2OQ1 A;  1R1S A;  1D4W A;  4OHI A;  1BKM A;  4A4B A;  5EHP A;  2EYZ A;  1KA7 A;  1A1E A;  1D1Z A;  4D8K A;  3PLF B;  1JYQ A;  1A07 A;  4WWQ A;  1IJR A;  1LUN A;  1YVL A;  1BLK A;  1M27 A;  3EAC A;  1O47 A;  2IUH A;  4GWF A;  4ROJ A;  1BKL A;  1O4R A;  3S8L A;  1UUS A;  1Z3K A;  3MAZ A;  4E93 A;  1NZL A;  3CBL A;  1BG1 A;  1R1P A;  1AYA A; 
#chains in the Genus database with same CATH topology
 3VRY A;  5DC0 B;  2Y1N A;  2RVF A;  1LUI A;  1O4J A;  1O4N A;  2DVJ A;  2DLZ A;  2ROR A;  3C7I A;  4FBN A;  2YU7 A;  1H9O A;  5BO4 A;  1MIL A;  2AUG A;  4LUE A;  3TKZ A;  1BM2 A;  1FYR A;  1BHH A;  2GE9 A;  1FU5 A;  3VS3 A;  4JEG A;  5GJI A;  2LQN A;  1HCT B;  3N84 A;  2CIA A;  3IMD A;  2EYV A;  1O41 A;  1BHH B;  1B47 A;  5J3X A;  3GQI B;  1O4O A;  3VS1 A;  5DC9 A;  1PIC A;  3K2M A;  1X6C A;  3HIZ B;  3ZNI A;  2GSB A;  2L6K A;  4NWF A;  3US4 A;  1GHU A;  2HDX A;  1RPY A;  2EU0 A;  1CSY A;  4K45 A;  2DM0 A;  4K11 A;  4FL2 A;  2EOB A;  2QMS A;  1QG1 E;  2CRH A;  1O4K A;  1LKL A;  2AOB A;  1Y57 A;  5EEL A;  1ZFP E;  2LNW A;  2XP1 A;  1JYU A;  1O4B A;  2PLE A;  1QCF A;  4U17 A;  5IBS A;  3GXW A;  1AOU F;  3QWY A;  2C9W A;  3T04 A;  5AUL A;  1OO3 A;  1TCE A;  1SKJ A;  3GXX A;  1D4T A;  5I6V A;  3VS7 A;  3CWG A;  4FL3 A;  1O4F A;  1AYB A;  2FO0 A;  4JGH A;  1O4G A;  1SHD A;  1CWD L;  1NRV A;  1Y1U A;  2C0T A;  3MXC A;  2PLD A;  3N8M A;  1A09 A;  1A08 A;  4DGX A;  4F59 A;  3OB2 B;  2OZO A;  1A1B A;  1SPR A;  3OB1 B;  1O42 A;  1O4L A;  1O45 A;  2LNX A;  4LUD A;  1HCS B;  1A1A A;  2MK2 A;  3OP0 A;  1F2F A;  3IN7 A;  1KSW A;  4EIH A;  2SHP A;  4A4C A;  1LKK A;  3LYV A;  1I3Z A;  1QAD A;  2EL8 A;  2CI9 A;  2EO3 A;  3VS2 A;  2KK6 A;  3VS0 A;  1F1W A;  4K2R A;  3VS5 A;  1BMB A;  3QWX X;  1XA6 A;  3KFJ A;  1O4I A;  1GRI A;  3BUN B;  4GL9 E;  4EY0 A;  2KNO A;  2AOA A;  5CDW A;  3VS6 A;  2MRJ A;  1CWE A;  3PQZ A;  2PNA A;  1G83 A;  1X0N A;  2CI8 A;  4H1O A;  3S8O A;  1O4H A;  1SPS A;  2MC1 A;  1O44 A;  3PSK A;  2HCK A;  4P9V A;  1WQU A;  1BLJ A;  4F5B A;  2MRK A;  1AB2 A;  2H5K A;  4L1B B;  5IBM A;  2IUI A;  1OPL A;  1O4P A;  5D0J A;  1O4D A;  2HDV A;  4K44 A;  1O4M A;  3HHM B;  4F5A A;  2H46 E;  1KA6 A;  2HUW A;  2L3T A;  2K7A B;  3M7F A;  3MXY A;  5AXI A;  3OVE A;  3S9K A;  3PJP A;  1O4Q A;  2ABL A;  3UF4 A;  1P13 A;  1R1Q A;  1KC2 A;  1IS0 A;  1O43 A;  2SRC A;  2MQI A;  3IMJ A;  1LUM A;  4XZ1 A;  2PNB A;  2KGY A;  3EAZ A;  4JE4 A;  3VGO A;  2VIF A;  3BUO B;  2CR4 A;  2HMH A;  3PSJ A;  3VRZ A;  5EEQ A;  2C0O A;  2EYY A;  2ECD A;  1CJ1 A;  4TZI A;  5HKY A;  1O4C A;  3UYO A;  1AOT F;  2YSX A;  4OHE A;  5EG3 B;  2EKX A;  1SHB A;  1A1C A;  1AYC A;  1O46 A;  1BF5 A;  2K79 B;  2IUG A;  2Y1M A;  4H34 A;  1FU6 A;  4U1P A;  1O49 A;  4E68 A;  4QSY A;  2ETZ A;  3VRP A;  1O4A A;  2H8H A;  2IZV A;  3PS5 A;  2RMX A;  1O4E A;  3VRR A;  1BHF A;  2RSY A;  1FBZ A;  4OHL A;  4OHH A;  1BFI A;  5EHR A;  2PTK A;  1TZE E;  1NZV A;  3BUM B;  1BFJ A;  3WA4 A;  5KAZ A;  4M4Z A;  1SHA A;  4DGP A;  1RJA A;  1LCJ A;  3VS4 A;  2C0I A;  1OPK A;  1YVH A;  2CBL A;  1K9A A;  1FBV A;  2CS0 A;  5HKZ A;  2L4K A;  2DX0 A;  3CXL A;  2LCT A;  3BUX B;  3HCK A;  1AYD A;  2B3O A;  2LRA A;  1UUR A;  2EO6 A;  1LCK A;  3VRQ A;  4NWG A;  1JU5 A;  3BUW B;  3BKB A;  4XZ0 A;  5GJH A;  1A81 A;  4X6S A;  3OV1 A;  1JWO A;  1AD5 A;  1M61 A;  4OHD A;  1O48 A;  3K2T A;  5HKW A;  4P9Z A;  3VRN A;  2JYQ A;  1FHS A;  1MW4 A;  4GPL B;  2DLY A;  2BBU A;  1OO4 A;  5DF6 A;  1CSZ A;  3S8N A;  1FMK A;  3PFV A;  1LUK A;  3N7Y A;  2FCI A;  3IN8 A;  1X27 A;  1RQQ C;  3NHN A;  2LQW A;  2Y3A B;  3CD3 A;  2DCR A;  5DC4 A;  1JYR A;  3VRO A;  3TL0 A;  2OQ1 A;  1R1S A;  1D4W A;  4OHI A;  1BKM A;  4A4B A;  5EHP A;  2EYZ A;  1KA7 A;  1A1E A;  1D1Z A;  4D8K A;  3PLF B;  1JYQ A;  1A07 A;  4WWQ A;  1IJR A;  1LUN A;  1YVL A;  1BLK A;  1M27 A;  3EAC A;  1O47 A;  2IUH A;  4GWF A;  4ROJ A;  1BKL A;  1O4R A;  3S8L A;  1UUS A;  1Z3K A;  3MAZ A;  4E93 A;  1NZL A;  3CBL A;  1BG1 A;  1R1P A;  1AYA A; 
#chains in the Genus database with same CATH homology
 3VRY A;  5DC0 B;  2Y1N A;  2RVF A;  1LUI A;  1O4J A;  1O4N A;  2DVJ A;  2DLZ A;  2ROR A;  3C7I A;  4FBN A;  2YU7 A;  1H9O A;  5BO4 A;  1MIL A;  2AUG A;  4LUE A;  3TKZ A;  1BM2 A;  1FYR A;  1BHH A;  2GE9 A;  1FU5 A;  3VS3 A;  4JEG A;  5GJI A;  2LQN A;  1HCT B;  3N84 A;  2CIA A;  3IMD A;  2EYV A;  1O41 A;  1BHH B;  1B47 A;  5J3X A;  3GQI B;  1O4O A;  3VS1 A;  5DC9 A;  1PIC A;  3K2M A;  1X6C A;  3HIZ B;  3ZNI A;  2GSB A;  2L6K A;  4NWF A;  3US4 A;  1GHU A;  2HDX A;  1RPY A;  2EU0 A;  1CSY A;  4K45 A;  2DM0 A;  4K11 A;  4FL2 A;  2EOB A;  2QMS A;  1QG1 E;  2CRH A;  1O4K A;  1LKL A;  2AOB A;  1Y57 A;  5EEL A;  1ZFP E;  2LNW A;  2XP1 A;  1JYU A;  1O4B A;  2PLE A;  1QCF A;  4U17 A;  5IBS A;  3GXW A;  1AOU F;  3QWY A;  2C9W A;  3T04 A;  5AUL A;  1OO3 A;  1TCE A;  1SKJ A;  3GXX A;  1D4T A;  5I6V A;  3VS7 A;  3CWG A;  4FL3 A;  1O4F A;  1AYB A;  2FO0 A;  4JGH A;  1O4G A;  1SHD A;  1CWD L;  1NRV A;  1Y1U A;  2C0T A;  3MXC A;  2PLD A;  3N8M A;  1A09 A;  1A08 A;  4DGX A;  4F59 A;  3OB2 B;  2OZO A;  1A1B A;  1SPR A;  3OB1 B;  1O42 A;  1O4L A;  1O45 A;  2LNX A;  4LUD A;  1HCS B;  1A1A A;  2MK2 A;  3OP0 A;  1F2F A;  3IN7 A;  1KSW A;  4EIH A;  2SHP A;  4A4C A;  1LKK A;  1I3Z A;  1QAD A;  2EL8 A;  2CI9 A;  2EO3 A;  3VS2 A;  2KK6 A;  3VS0 A;  1F1W A;  4K2R A;  3VS5 A;  1BMB A;  3QWX X;  1XA6 A;  3KFJ A;  1O4I A;  1GRI A;  3BUN B;  4GL9 E;  4EY0 A;  2KNO A;  2AOA A;  5CDW A;  3VS6 A;  2MRJ A;  1CWE A;  3PQZ A;  2PNA A;  1G83 A;  1X0N A;  2CI8 A;  4H1O A;  3S8O A;  1O4H A;  1SPS A;  2MC1 A;  1O44 A;  3PSK A;  2HCK A;  4P9V A;  1WQU A;  1BLJ A;  4F5B A;  2MRK A;  1AB2 A;  2H5K A;  4L1B B;  5IBM A;  2IUI A;  1OPL A;  1O4P A;  5D0J A;  1O4D A;  2HDV A;  4K44 A;  1O4M A;  3HHM B;  4F5A A;  2H46 E;  1KA6 A;  2HUW A;  2L3T A;  2K7A B;  3M7F A;  3MXY A;  5AXI A;  3OVE A;  3S9K A;  3PJP A;  1O4Q A;  2ABL A;  3UF4 A;  1P13 A;  1R1Q A;  1KC2 A;  1IS0 A;  1O43 A;  2SRC A;  2MQI A;  3IMJ A;  1LUM A;  4XZ1 A;  2PNB A;  3EAZ A;  4JE4 A;  3VGO A;  2VIF A;  3BUO B;  2CR4 A;  2HMH A;  3PSJ A;  3VRZ A;  5EEQ A;  2C0O A;  2EYY A;  2ECD A;  1CJ1 A;  4TZI A;  5HKY A;  1O4C A;  3UYO A;  1AOT F;  2YSX A;  4OHE A;  5EG3 B;  2EKX A;  1SHB A;  1A1C A;  1AYC A;  1O46 A;  1BF5 A;  2K79 B;  2IUG A;  2Y1M A;  4H34 A;  1FU6 A;  4U1P A;  1O49 A;  4E68 A;  4QSY A;  2ETZ A;  3VRP A;  1O4A A;  2H8H A;  2IZV A;  3PS5 A;  2RMX A;  1O4E A;  3VRR A;  1BHF A;  2RSY A;  1FBZ A;  4OHL A;  4OHH A;  1BFI A;  5EHR A;  2PTK A;  1TZE E;  1NZV A;  3BUM B;  1BFJ A;  3WA4 A;  5KAZ A;  4M4Z A;  1SHA A;  4DGP A;  1RJA A;  1LCJ A;  3VS4 A;  2C0I A;  1OPK A;  1YVH A;  2CBL A;  1K9A A;  1FBV A;  2CS0 A;  5HKZ A;  2L4K A;  2DX0 A;  3CXL A;  2LCT A;  3BUX B;  3HCK A;  1AYD A;  2B3O A;  1UUR A;  2EO6 A;  1LCK A;  3VRQ A;  4NWG A;  1JU5 A;  3BUW B;  3BKB A;  4XZ0 A;  5GJH A;  1A81 A;  4X6S A;  3OV1 A;  1JWO A;  1AD5 A;  1M61 A;  4OHD A;  1O48 A;  5HKW A;  4P9Z A;  3VRN A;  2JYQ A;  1FHS A;  1MW4 A;  4GPL B;  2DLY A;  2BBU A;  1OO4 A;  5DF6 A;  1CSZ A;  3S8N A;  1FMK A;  3PFV A;  1LUK A;  3N7Y A;  2FCI A;  3IN8 A;  1X27 A;  1RQQ C;  3NHN A;  2LQW A;  2Y3A B;  3CD3 A;  2DCR A;  5DC4 A;  1JYR A;  3VRO A;  3TL0 A;  2OQ1 A;  1R1S A;  1D4W A;  4OHI A;  1BKM A;  4A4B A;  5EHP A;  2EYZ A;  1KA7 A;  1A1E A;  1D1Z A;  4D8K A;  3PLF B;  1JYQ A;  1A07 A;  4WWQ A;  1IJR A;  1LUN A;  1YVL A;  1BLK A;  1M27 A;  3EAC A;  1O47 A;  2IUH A;  4GWF A;  4ROJ A;  1BKL A;  1O4R A;  3S8L A;  1UUS A;  1Z3K A;  3MAZ A;  4E93 A;  1NZL A;  3CBL A;  1BG1 A;  1R1P A;  1AYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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