3IMDA

Crystal structure of the grb2 sh2 domain in complex with a flexible ac-py-q-n-nh2 tripeptide mimic
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
101
structure length
101
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
pubmed doi rcsb
molecule keywords Growth factor receptor-bound protein 2
molecule tags Signaling protein/peptide
source organism Homo sapiens
total genus 23
structure length 101
sequence length 101
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3imdA00
2AOBA 5HKZA 4D8KA 5GJHA 3S8LA 3IN7A 5GJIA 3S9KA 3PQZA 2C9WA 2GSBA 5HKYA 2MRJA 4H1OA 2ECDA 1QG1E 1O4GA 5AXIA 2SRCA 2C0IA 1NRVA 3ZNIA 3TL0A 1CJ1A 2LCTA 2Y3AB 1CSYA 2DLYA 3TKZA 4GWFA 4U1PA 1BHFA 3VRYA 2OQ1A 1K9AA 2L6KA 3BUOB 2PTKA 1AD5A 5BO4A 2CI8A 1FU5A 2L3TA 5CDWA 4E68A 3MXYA 2MC1A 3VS2A 2MK2A 3BUMB 1X6CA 1KA6A 5EHPA 2ETZA 3PSKA 2XP1A 1BF5A 1AYDA 1TCEA 1BKMA 2PLEA 3EAZA 1H9OA 4OHDA 5DC4A 3K2MA 1R1QA 2PLDA 3MAZA 4ROJA 1BKLA 1Y57A 1IJRA 1JWOA 1O49A 4FL2A 1QCFA 3PSJA 1AYBA 3OVEA 3VRRA 1FMKA 1FBVA 1O4OA 1RPYA 2HDVA 2Y1NA 4LUDA 1NZLA 3MXCA 1RQQC 1BLJA 2EU0A 1O46A 4TZIA 1BM2A 2EYYA 2SHPA 2IZVA 3VS5A 1LKLA 1A81A 1A1EA 1O4HA 1R1PA 2AOAA 1O43A 1O4QA 1LUMA 4JE4A 1I3ZA 4OHLA 1O42A 3US4A 4QSYA 1UUSA 1O4JA 3OB2B 2CIAA 3C7IA 1M27A 4K45A 4NWFA 1D4WA 1OPLA 4U17A 4GPLB 4EY0A 2MRKA 1BHHA 1ZFPE 1O4DA 1BLKA 4P9ZA 1LUNA 4JGHA 3VS7A 2IUIA 1SPRA 1O4LA 3VRPA 4F59A 1SHBA 3S8OA 1BHHB 1F2FA 1FHSA 4DGXA 2EYZA 4FL3A 1LCKA 1JYUA 2DX0A 2VIFA 1TZEE 4OHEA 3VS1A 2PNBA 3HIZB 3OP0A 2AUGA 1OPKA 4L1BB 1LKKA 4XZ1A 1BG1A 3NHNA 3BUWB 2K7AB 1F1WA 1O4FA 5IBMA 4X6SA 1MW4A 1BFJA 1A1AA 3WA4A 1KSWA 1O4IA 1O41A 3T04A 1A1BA 4DGPA 2QMSA 1G83A 1MILA 3OB1B 5D0JA 4GL9E 2ABLA 3UF4A 2IUGA 3QWXX 3VRQA 4E93A 1UURA 5J3XA 3CWGA 1O48A 3CBLA 1AB2A 2B3OA 2KNOA 1YVHA 1AYCA 2CI9A 2EO6A 3VS0A 3CD3A 2CBLA 4K2RA 1SKJA 1O44A 3EACA 2IUHA 1CSZA 3M7FA 3VRZA 2FO0A 3IMDA 3N8MA 1B47A 1P13A 2OZOA 1O4AA 3PJPA 5KAZA 1O4CA 1M61A 1X27A 2HCKA 1CWDL 2DCRA 1D4TA 2EO3A 2RSYA 1AOTF 2RORA 3GQIB 4EIHA 1BFIA 1O4NA 5HKWA 1OO3A 2LNWA 1O45A 1Z3KA 4F5AA 1A08A 1WQUA 5DC9A 2YSXA 1X0NA 2EKXA 3QWYA 1JYRA 1YVLA 4OHHA 1CWEA 3BUXB 3HHMB 2HDXA 2H5KA 3VS6A 2DVJA 1IS0A 1R1SA 2C0TA 5EELA 4K44A 1FYRA 3VS3A 1PICA 2DM0A 2FCIA 2LQWA 4LUEA 3BKBA 1QADA 1O4PA 3HCKA 1A07A 2HMHA 4A4BA 3CXLA 2GE9A 2H46E 5EEQA 1D1ZA 3IMJA 1GHUA 2KK6A 2H8HA 4WWQA 1RJAA 3VGOA 1Y1UA 1OO4A 1HCSB 1AYAA 1SPSA 5IBSA 1KC2A 5EG3B 2LQNA 2C0OA 1O4MA 3VS4A 4F5BA 2PNAA 1AOUF 1SHDA 1O4EA 1A1CA 2CR4A 2EYVA 2L4KA 4K11A 3IN8A 1XA6A 2HUWA 3PS5A 3S8NA 1SHAA 5I6VA 2K79B 3KFJA 1FU6A 4A4CA 1O47A 3UYOA 2RVFA 3VRNA 1GRIA 3VROA 4M4ZA 1FBZA 3PFVA 5EHRA 3N84A 1KA7A 5AULA 1JU5A 4NWGA 4JEGA 4P9VA 3OV1A 4FBNA 3GXXA 1BMBA 2EL8A 1LUKA 2BBUA 3GXWA 3PLFB 1LUIA 1O4KA 5DF6A 2EOBA 5DC0B 3N7YA 3BUNB 4H34A 4XZ0A 1LCJA 2CRHA 1O4RA 1A09A 2DLZA 1NZVA 1O4BA 2JYQA 2CS0A 2MQIA 2RMXA 1JYQA 2LNXA 2Y1MA 4OHIA 2YU7A 1HCTB
chains in the Genus database with same CATH superfamily
2AOBA 5HKZA 4D8KA 5GJHA 3S8LA 3IN7A 5GJIA 3S9KA 3PQZA 2C9WA 2GSBA 5HKYA 2MRJA 4H1OA 2ECDA 1QG1E 1O4GA 5AXIA 2SRCA 2C0IA 1NRVA 3ZNIA 3TL0A 1CJ1A 2LCTA 2Y3AB 1CSYA 2DLYA 3TKZA 4GWFA 4U1PA 1BHFA 3VRYA 2OQ1A 1K9AA 2L6KA 3BUOB 2PTKA 1AD5A 5BO4A 2CI8A 1FU5A 2L3TA 5CDWA 4E68A 3MXYA 2MC1A 3VS2A 2MK2A 3BUMB 1X6CA 1KA6A 5EHPA 2ETZA 3PSKA 2XP1A 1BF5A 1AYDA 1TCEA 1BKMA 2PLEA 3EAZA 1H9OA 4OHDA 5DC4A 3K2MA 1R1QA 2PLDA 3MAZA 4ROJA 1BKLA 1Y57A 1IJRA 1JWOA 1O49A 4FL2A 1QCFA 3PSJA 1AYBA 3OVEA 3VRRA 1FMKA 1FBVA 1O4OA 1RPYA 2HDVA 2KGYA 2Y1NA 4LUDA 1NZLA 3MXCA 1RQQC 1BLJA 2EU0A 1O46A 4TZIA 1BM2A 2EYYA 2SHPA 2IZVA 3VS5A 1LKLA 1A81A 1A1EA 1O4HA 1R1PA 2AOAA 1O43A 1O4QA 1LUMA 4JE4A 1I3ZA 4OHLA 1O42A 3US4A 4QSYA 1UUSA 1O4JA 3OB2B 2CIAA 3C7IA 1M27A 4K45A 4NWFA 1D4WA 1OPLA 4U17A 4GPLB 4EY0A 2MRKA 1BHHA 1ZFPE 1O4DA 1BLKA 4P9ZA 1LUNA 4JGHA 3VS7A 2IUIA 1SPRA 1O4LA 3VRPA 4F59A 1SHBA 3S8OA 1BHHB 1F2FA 1FHSA 4DGXA 2EYZA 4FL3A 1LCKA 1JYUA 3LYVA 2DX0A 2VIFA 1TZEE 4OHEA 3VS1A 2PNBA 3HIZB 3OP0A 2AUGA 1OPKA 4L1BB 1LKKA 4XZ1A 1BG1A 3NHNA 3BUWB 2K7AB 1F1WA 1O4FA 5IBMA 4X6SA 1MW4A 1BFJA 1A1AA 3WA4A 1KSWA 1O4IA 1O41A 3T04A 1A1BA 4DGPA 2QMSA 1G83A 1MILA 3OB1B 5D0JA 4GL9E 2ABLA 3UF4A 2IUGA 3QWXX 3VRQA 4E93A 1UURA 5J3XA 3CWGA 1O48A 3CBLA 1AB2A 2B3OA 2KNOA 1YVHA 1AYCA 2CI9A 2EO6A 3VS0A 3CD3A 2CBLA 4K2RA 1SKJA 1O44A 3EACA 2IUHA 1CSZA 3M7FA 3VRZA 2FO0A 3IMDA 3N8MA 1B47A 1P13A 2OZOA 1O4AA 3PJPA 5KAZA 1O4CA 1M61A 1X27A 2HCKA 1CWDL 2DCRA 1D4TA 2EO3A 2RSYA 1AOTF 2RORA 3GQIB 4EIHA 1BFIA 1O4NA 5HKWA 1OO3A 2LNWA 1O45A 1Z3KA 4F5AA 1A08A 1WQUA 2YSXA 1X0NA 2EKXA 3QWYA 5DC9A 1JYRA 1YVLA 4OHHA 1CWEA 3BUXB 3HHMB 2HDXA 2H5KA 3VS6A 2DVJA 1IS0A 1R1SA 2C0TA 5EELA 4K44A 1FYRA 3VS3A 1PICA 2DM0A 2FCIA 2LQWA 4LUEA 3BKBA 1QADA 1O4PA 3HCKA 1A07A 2HMHA 4A4BA 3CXLA 2GE9A 2H46E 5EEQA 1D1ZA 3IMJA 1GHUA 2KK6A 2H8HA 4WWQA 1RJAA 3K2TA 3VGOA 1Y1UA 1OO4A 1HCSB 1AYAA 1SPSA 5IBSA 1KC2A 5EG3B 2LQNA 2C0OA 1O4MA 3VS4A 4F5BA 2PNAA 1AOUF 1SHDA 1O4EA 1A1CA 2CR4A 2EYVA 2L4KA 2LRAA 4K11A 3IN8A 1XA6A 2HUWA 3PS5A 3S8NA 1SHAA 5I6VA 2K79B 3KFJA 1FU6A 4A4CA 1O47A 3UYOA 2RVFA 3VRNA 1GRIA 3VROA 4M4ZA 1FBZA 3PFVA 5EHRA 3N84A 1KA7A 5AULA 1JU5A 4NWGA 4JEGA 4P9VA 3OV1A 4FBNA 3GXXA 1BMBA 2EL8A 1LUKA 2BBUA 3GXWA 3PLFB 1LUIA 1O4KA 5DF6A 2EOBA 5DC0B 3N7YA 3BUNB 4H34A 4XZ0A 1LCJA 2CRHA 1O4RA 1A09A 2DLZA 1NZVA 1O4BA 2JYQA 2CS0A 2MQIA 2RMXA 1JYQA 2LNXA 2Y1MA 4OHIA 2YU7A 1HCTB
chains in the Genus database with same CATH topology
2AOBA 5HKZA 4D8KA 5GJHA 3S8LA 3IN7A 5GJIA 3S9KA 3PQZA 2C9WA 2GSBA 5HKYA 2MRJA 4H1OA 2ECDA 1QG1E 1O4GA 5AXIA 2SRCA 2C0IA 1NRVA 3ZNIA 3TL0A 1CJ1A 2LCTA 2Y3AB 1CSYA 2DLYA 3TKZA 4GWFA 4U1PA 1BHFA 3VRYA 2OQ1A 1K9AA 2L6KA 3BUOB 2PTKA 1AD5A 5BO4A 2CI8A 1FU5A 2L3TA 5CDWA 4E68A 3MXYA 2MC1A 3VS2A 2MK2A 3BUMB 1X6CA 1KA6A 5EHPA 2ETZA 3PSKA 2XP1A 1BF5A 1AYDA 1TCEA 1BKMA 2PLEA 3EAZA 1H9OA 4OHDA 5DC4A 3K2MA 1R1QA 2PLDA 3MAZA 4ROJA 1BKLA 1Y57A 1IJRA 1JWOA 1O49A 4FL2A 1QCFA 3PSJA 1AYBA 3OVEA 3VRRA 1FMKA 1FBVA 1O4OA 1RPYA 2HDVA 2Y1NA 4LUDA 1NZLA 3MXCA 1RQQC 1BLJA 2EU0A 1O46A 4TZIA 1BM2A 2EYYA 2SHPA 2IZVA 3VS5A 1LKLA 1A81A 1A1EA 1O4HA 1R1PA 2AOAA 1O43A 1O4QA 1LUMA 4JE4A 1I3ZA 4OHLA 1O42A 3US4A 4QSYA 1UUSA 1O4JA 3OB2B 2CIAA 3C7IA 1M27A 4K45A 4NWFA 1D4WA 1OPLA 4U17A 4GPLB 4EY0A 2MRKA 1BHHA 1ZFPE 1O4DA 1BLKA 4P9ZA 1LUNA 4JGHA 3VS7A 2IUIA 1SPRA 1O4LA 3VRPA 4F59A 1SHBA 3S8OA 1BHHB 1F2FA 1FHSA 4DGXA 2EYZA 4FL3A 1LCKA 1JYUA 2DX0A 2VIFA 1TZEE 4OHEA 3VS1A 2PNBA 3HIZB 3OP0A 2AUGA 1OPKA 4L1BB 1LKKA 4XZ1A 1BG1A 3NHNA 3BUWB 2K7AB 1F1WA 1O4FA 5IBMA 4X6SA 1MW4A 1BFJA 1A1AA 3WA4A 1KSWA 1O4IA 1O41A 3T04A 1A1BA 4DGPA 2QMSA 1G83A 1MILA 3OB1B 5D0JA 4GL9E 2ABLA 3UF4A 2IUGA 3QWXX 3VRQA 4E93A 1UURA 5J3XA 3CWGA 1O48A 3CBLA 1AB2A 2B3OA 2KNOA 1YVHA 1AYCA 2CI9A 2EO6A 3VS0A 3CD3A 2CBLA 4K2RA 1SKJA 1O44A 3EACA 2IUHA 1CSZA 3M7FA 3VRZA 2FO0A 3IMDA 3N8MA 1B47A 1P13A 2OZOA 1O4AA 3PJPA 5KAZA 1O4CA 1M61A 1X27A 2HCKA 1CWDL 2DCRA 1D4TA 2EO3A 2RSYA 1AOTF 2RORA 3GQIB 4EIHA 1BFIA 1O4NA 5HKWA 1OO3A 2LNWA 1O45A 1Z3KA 4F5AA 1A08A 1WQUA 5DC9A 2YSXA 1X0NA 2EKXA 3QWYA 1JYRA 1YVLA 4OHHA 1CWEA 3BUXB 3HHMB 2HDXA 2H5KA 3VS6A 2DVJA 1IS0A 1R1SA 2C0TA 5EELA 4K44A 1FYRA 3VS3A 1PICA 2DM0A 2FCIA 2LQWA 4LUEA 3BKBA 1QADA 1O4PA 3HCKA 1A07A 2HMHA 4A4BA 3CXLA 2GE9A 2H46E 5EEQA 1D1ZA 3IMJA 1GHUA 2KK6A 2H8HA 4WWQA 1RJAA 3VGOA 1Y1UA 1OO4A 1HCSB 1AYAA 1SPSA 5IBSA 1KC2A 5EG3B 2LQNA 2C0OA 1O4MA 3VS4A 4F5BA 2PNAA 1AOUF 1SHDA 1O4EA 1A1CA 2CR4A 2EYVA 2L4KA 4K11A 3IN8A 1XA6A 2HUWA 3PS5A 3S8NA 1SHAA 5I6VA 2K79B 3KFJA 1FU6A 4A4CA 1O47A 3UYOA 2RVFA 3VRNA 1GRIA 3VROA 4M4ZA 1FBZA 3PFVA 5EHRA 3N84A 1KA7A 5AULA 1JU5A 4NWGA 4JEGA 4P9VA 3OV1A 4FBNA 3GXXA 1BMBA 2EL8A 1LUKA 2BBUA 3GXWA 3PLFB 1LUIA 1O4KA 5DF6A 2EOBA 5DC0B 3N7YA 3BUNB 4H34A 4XZ0A 1LCJA 2CRHA 1O4RA 1A09A 2DLZA 1NZVA 1O4BA 2JYQA 2CS0A 2MQIA 2RMXA 1JYQA 2LNXA 2Y1MA 4OHIA 2YU7A 1HCTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AOB A;  5HKZ A;  4D8K A;  5GJH A;  3S8L A;  3IN7 A;  5GJI A;  3S9K A;  3PQZ A;  2C9W A;  2GSB A;  5HKY A;  2MRJ A;  4H1O A;  2ECD A;  1QG1 E;  1O4G A;  5AXI A;  2SRC A;  2C0I A;  1NRV A;  3ZNI A;  3TL0 A;  1CJ1 A;  2LCT A;  2Y3A B;  1CSY A;  2DLY A;  3TKZ A;  4GWF A;  4U1P A;  1BHF A;  3VRY A;  2OQ1 A;  1K9A A;  2L6K A;  3BUO B;  2PTK A;  1AD5 A;  5BO4 A;  2CI8 A;  1FU5 A;  2L3T A;  5CDW A;  4E68 A;  3MXY A;  2MC1 A;  3VS2 A;  2MK2 A;  3BUM B;  1X6C A;  1KA6 A;  5EHP A;  2ETZ A;  3PSK A;  2XP1 A;  1BF5 A;  1AYD A;  1TCE A;  1BKM A;  2PLE A;  3EAZ A;  1H9O A;  4OHD A;  5DC4 A;  3K2M A;  1R1Q A;  2PLD A;  3MAZ A;  4ROJ A;  1BKL A;  1Y57 A;  1IJR A;  1JWO A;  1O49 A;  4FL2 A;  1QCF A;  3PSJ A;  1AYB A;  3OVE A;  3VRR A;  1FMK A;  1FBV A;  1O4O A;  1RPY A;  2HDV A;  2Y1N A;  4LUD A;  1NZL A;  3MXC A;  1RQQ C;  1BLJ A;  2EU0 A;  1O46 A;  4TZI A;  1BM2 A;  2EYY A;  2SHP A;  2IZV A;  3VS5 A;  1LKL A;  1A81 A;  1A1E A;  1O4H A;  1R1P A;  2AOA A;  1O43 A;  1O4Q A;  1LUM A;  4JE4 A;  1I3Z A;  4OHL A;  1O42 A;  3US4 A;  4QSY A;  1UUS A;  1O4J A;  3OB2 B;  2CIA A;  3C7I A;  1M27 A;  4K45 A;  4NWF A;  1D4W A;  1OPL A;  4U17 A;  4GPL B;  4EY0 A;  2MRK A;  1BHH A;  1ZFP E;  1O4D A;  1BLK A;  4P9Z A;  1LUN A;  4JGH A;  3VS7 A;  2IUI A;  1SPR A;  1O4L A;  3VRP A;  4F59 A;  1SHB A;  3S8O A;  1BHH B;  1F2F A;  1FHS A;  4DGX A;  2EYZ A;  4FL3 A;  1LCK A;  1JYU A;  2DX0 A;  2VIF A;  1TZE E;  4OHE A;  3VS1 A;  2PNB A;  3HIZ B;  3OP0 A;  2AUG A;  1OPK A;  4L1B B;  1LKK A;  4XZ1 A;  1BG1 A;  3NHN A;  3BUW B;  2K7A B;  1F1W A;  1O4F A;  5IBM A;  4X6S A;  1MW4 A;  1BFJ A;  1A1A A;  3WA4 A;  1KSW A;  1O4I A;  1O41 A;  3T04 A;  1A1B A;  4DGP A;  2QMS A;  1G83 A;  1MIL A;  3OB1 B;  5D0J A;  4GL9 E;  2ABL A;  3UF4 A;  2IUG A;  3QWX X;  3VRQ A;  4E93 A;  1UUR A;  5J3X A;  3CWG A;  1O48 A;  3CBL A;  1AB2 A;  2B3O A;  2KNO A;  1YVH A;  1AYC A;  2CI9 A;  2EO6 A;  3VS0 A;  3CD3 A;  2CBL A;  4K2R A;  1SKJ A;  1O44 A;  3EAC A;  2IUH A;  1CSZ A;  3M7F A;  3VRZ A;  2FO0 A;  3IMD A;  3N8M A;  1B47 A;  1P13 A;  2OZO A;  1O4A A;  3PJP A;  5KAZ A;  1O4C A;  1M61 A;  1X27 A;  2HCK A;  1CWD L;  2DCR A;  1D4T A;  2EO3 A;  2RSY A;  1AOT F;  2ROR A;  3GQI B;  4EIH A;  1BFI A;  1O4N A;  5HKW A;  1OO3 A;  2LNW A;  1O45 A;  1Z3K A;  4F5A A;  1A08 A;  1WQU A;  5DC9 A;  2YSX A;  1X0N A;  2EKX A;  3QWY A;  1JYR A;  1YVL A;  4OHH A;  1CWE A;  3BUX B;  3HHM B;  2HDX A;  2H5K A;  3VS6 A;  2DVJ A;  1IS0 A;  1R1S A;  2C0T A;  5EEL A;  4K44 A;  1FYR A;  3VS3 A;  1PIC A;  2DM0 A;  2FCI A;  2LQW A;  4LUE A;  3BKB A;  1QAD A;  1O4P A;  3HCK A;  1A07 A;  2HMH A;  4A4B A;  3CXL A;  2GE9 A;  2H46 E;  5EEQ A;  1D1Z A;  3IMJ A;  1GHU A;  2KK6 A;  2H8H A;  4WWQ A;  1RJA A;  3VGO A;  1Y1U A;  1OO4 A;  1HCS B;  1AYA A;  1SPS A;  5IBS A;  1KC2 A;  5EG3 B;  2LQN A;  2C0O A;  1O4M A;  3VS4 A;  4F5B A;  2PNA A;  1AOU F;  1SHD A;  1O4E A;  1A1C A;  2CR4 A;  2EYV A;  2L4K A;  4K11 A;  3IN8 A;  1XA6 A;  2HUW A;  3PS5 A;  3S8N A;  1SHA A;  5I6V A;  2K79 B;  3KFJ A;  1FU6 A;  4A4C A;  1O47 A;  3UYO A;  2RVF A;  3VRN A;  1GRI A;  3VRO A;  4M4Z A;  1FBZ A;  3PFV A;  5EHR A;  3N84 A;  1KA7 A;  5AUL A;  1JU5 A;  4NWG A;  4JEG A;  4P9V A;  3OV1 A;  4FBN A;  3GXX A;  1BMB A;  2EL8 A;  1LUK A;  2BBU A;  3GXW A;  3PLF B;  1LUI A;  1O4K A;  5DF6 A;  2EOB A;  5DC0 B;  3N7Y A;  3BUN B;  4H34 A;  4XZ0 A;  1LCJ A;  2CRH A;  1O4R A;  1A09 A;  2DLZ A;  1NZV A;  1O4B A;  2JYQ A;  2CS0 A;  2MQI A;  2RMX A;  1JYQ A;  2LNX A;  2Y1M A;  4OHI A;  2YU7 A;  1HCT B; 
#chains in the Genus database with same CATH topology
 2AOB A;  5HKZ A;  4D8K A;  5GJH A;  3S8L A;  3IN7 A;  5GJI A;  3S9K A;  3PQZ A;  2C9W A;  2GSB A;  5HKY A;  2MRJ A;  4H1O A;  2ECD A;  1QG1 E;  1O4G A;  5AXI A;  2SRC A;  2C0I A;  1NRV A;  3ZNI A;  3TL0 A;  1CJ1 A;  2LCT A;  2Y3A B;  1CSY A;  2DLY A;  3TKZ A;  4GWF A;  4U1P A;  1BHF A;  3VRY A;  2OQ1 A;  1K9A A;  2L6K A;  3BUO B;  2PTK A;  1AD5 A;  5BO4 A;  2CI8 A;  1FU5 A;  2L3T A;  5CDW A;  4E68 A;  3MXY A;  2MC1 A;  3VS2 A;  2MK2 A;  3BUM B;  1X6C A;  1KA6 A;  5EHP A;  2ETZ A;  3PSK A;  2XP1 A;  1BF5 A;  1AYD A;  1TCE A;  1BKM A;  2PLE A;  3EAZ A;  1H9O A;  4OHD A;  5DC4 A;  3K2M A;  1R1Q A;  2PLD A;  3MAZ A;  4ROJ A;  1BKL A;  1Y57 A;  1IJR A;  1JWO A;  1O49 A;  4FL2 A;  1QCF A;  3PSJ A;  1AYB A;  3OVE A;  3VRR A;  1FMK A;  1FBV A;  1O4O A;  1RPY A;  2HDV A;  2KGY A;  2Y1N A;  4LUD A;  1NZL A;  3MXC A;  1RQQ C;  1BLJ A;  2EU0 A;  1O46 A;  4TZI A;  1BM2 A;  2EYY A;  2SHP A;  2IZV A;  3VS5 A;  1LKL A;  1A81 A;  1A1E A;  1O4H A;  1R1P A;  2AOA A;  1O43 A;  1O4Q A;  1LUM A;  4JE4 A;  1I3Z A;  4OHL A;  1O42 A;  3US4 A;  4QSY A;  1UUS A;  1O4J A;  3OB2 B;  2CIA A;  3C7I A;  1M27 A;  4K45 A;  4NWF A;  1D4W A;  1OPL A;  4U17 A;  4GPL B;  4EY0 A;  2MRK A;  1BHH A;  1ZFP E;  1O4D A;  1BLK A;  4P9Z A;  1LUN A;  4JGH A;  3VS7 A;  2IUI A;  1SPR A;  1O4L A;  3VRP A;  4F59 A;  1SHB A;  3S8O A;  1BHH B;  1F2F A;  1FHS A;  4DGX A;  2EYZ A;  4FL3 A;  1LCK A;  1JYU A;  3LYV A;  2DX0 A;  2VIF A;  1TZE E;  4OHE A;  3VS1 A;  2PNB A;  3HIZ B;  3OP0 A;  2AUG A;  1OPK A;  4L1B B;  1LKK A;  4XZ1 A;  1BG1 A;  3NHN A;  3BUW B;  2K7A B;  1F1W A;  1O4F A;  5IBM A;  4X6S A;  1MW4 A;  1BFJ A;  1A1A A;  3WA4 A;  1KSW A;  1O4I A;  1O41 A;  3T04 A;  1A1B A;  4DGP A;  2QMS A;  1G83 A;  1MIL A;  3OB1 B;  5D0J A;  4GL9 E;  2ABL A;  3UF4 A;  2IUG A;  3QWX X;  3VRQ A;  4E93 A;  1UUR A;  5J3X A;  3CWG A;  1O48 A;  3CBL A;  1AB2 A;  2B3O A;  2KNO A;  1YVH A;  1AYC A;  2CI9 A;  2EO6 A;  3VS0 A;  3CD3 A;  2CBL A;  4K2R A;  1SKJ A;  1O44 A;  3EAC A;  2IUH A;  1CSZ A;  3M7F A;  3VRZ A;  2FO0 A;  3IMD A;  3N8M A;  1B47 A;  1P13 A;  2OZO A;  1O4A A;  3PJP A;  5KAZ A;  1O4C A;  1M61 A;  1X27 A;  2HCK A;  1CWD L;  2DCR A;  1D4T A;  2EO3 A;  2RSY A;  1AOT F;  2ROR A;  3GQI B;  4EIH A;  1BFI A;  1O4N A;  5HKW A;  1OO3 A;  2LNW A;  1O45 A;  1Z3K A;  4F5A A;  1A08 A;  1WQU A;  2YSX A;  1X0N A;  2EKX A;  3QWY A;  5DC9 A;  1JYR A;  1YVL A;  4OHH A;  1CWE A;  3BUX B;  3HHM B;  2HDX A;  2H5K A;  3VS6 A;  2DVJ A;  1IS0 A;  1R1S A;  2C0T A;  5EEL A;  4K44 A;  1FYR A;  3VS3 A;  1PIC A;  2DM0 A;  2FCI A;  2LQW A;  4LUE A;  3BKB A;  1QAD A;  1O4P A;  3HCK A;  1A07 A;  2HMH A;  4A4B A;  3CXL A;  2GE9 A;  2H46 E;  5EEQ A;  1D1Z A;  3IMJ A;  1GHU A;  2KK6 A;  2H8H A;  4WWQ A;  1RJA A;  3K2T A;  3VGO A;  1Y1U A;  1OO4 A;  1HCS B;  1AYA A;  1SPS A;  5IBS A;  1KC2 A;  5EG3 B;  2LQN A;  2C0O A;  1O4M A;  3VS4 A;  4F5B A;  2PNA A;  1AOU F;  1SHD A;  1O4E A;  1A1C A;  2CR4 A;  2EYV A;  2L4K A;  2LRA A;  4K11 A;  3IN8 A;  1XA6 A;  2HUW A;  3PS5 A;  3S8N A;  1SHA A;  5I6V A;  2K79 B;  3KFJ A;  1FU6 A;  4A4C A;  1O47 A;  3UYO A;  2RVF A;  3VRN A;  1GRI A;  3VRO A;  4M4Z A;  1FBZ A;  3PFV A;  5EHR A;  3N84 A;  1KA7 A;  5AUL A;  1JU5 A;  4NWG A;  4JEG A;  4P9V A;  3OV1 A;  4FBN A;  3GXX A;  1BMB A;  2EL8 A;  1LUK A;  2BBU A;  3GXW A;  3PLF B;  1LUI A;  1O4K A;  5DF6 A;  2EOB A;  5DC0 B;  3N7Y A;  3BUN B;  4H34 A;  4XZ0 A;  1LCJ A;  2CRH A;  1O4R A;  1A09 A;  2DLZ A;  1NZV A;  1O4B A;  2JYQ A;  2CS0 A;  2MQI A;  2RMX A;  1JYQ A;  2LNX A;  2Y1M A;  4OHI A;  2YU7 A;  1HCT B; 
#chains in the Genus database with same CATH homology
 2AOB A;  5HKZ A;  4D8K A;  5GJH A;  3S8L A;  3IN7 A;  5GJI A;  3S9K A;  3PQZ A;  2C9W A;  2GSB A;  5HKY A;  2MRJ A;  4H1O A;  2ECD A;  1QG1 E;  1O4G A;  5AXI A;  2SRC A;  2C0I A;  1NRV A;  3ZNI A;  3TL0 A;  1CJ1 A;  2LCT A;  2Y3A B;  1CSY A;  2DLY A;  3TKZ A;  4GWF A;  4U1P A;  1BHF A;  3VRY A;  2OQ1 A;  1K9A A;  2L6K A;  3BUO B;  2PTK A;  1AD5 A;  5BO4 A;  2CI8 A;  1FU5 A;  2L3T A;  5CDW A;  4E68 A;  3MXY A;  2MC1 A;  3VS2 A;  2MK2 A;  3BUM B;  1X6C A;  1KA6 A;  5EHP A;  2ETZ A;  3PSK A;  2XP1 A;  1BF5 A;  1AYD A;  1TCE A;  1BKM A;  2PLE A;  3EAZ A;  1H9O A;  4OHD A;  5DC4 A;  3K2M A;  1R1Q A;  2PLD A;  3MAZ A;  4ROJ A;  1BKL A;  1Y57 A;  1IJR A;  1JWO A;  1O49 A;  4FL2 A;  1QCF A;  3PSJ A;  1AYB A;  3OVE A;  3VRR A;  1FMK A;  1FBV A;  1O4O A;  1RPY A;  2HDV A;  2Y1N A;  4LUD A;  1NZL A;  3MXC A;  1RQQ C;  1BLJ A;  2EU0 A;  1O46 A;  4TZI A;  1BM2 A;  2EYY A;  2SHP A;  2IZV A;  3VS5 A;  1LKL A;  1A81 A;  1A1E A;  1O4H A;  1R1P A;  2AOA A;  1O43 A;  1O4Q A;  1LUM A;  4JE4 A;  1I3Z A;  4OHL A;  1O42 A;  3US4 A;  4QSY A;  1UUS A;  1O4J A;  3OB2 B;  2CIA A;  3C7I A;  1M27 A;  4K45 A;  4NWF A;  1D4W A;  1OPL A;  4U17 A;  4GPL B;  4EY0 A;  2MRK A;  1BHH A;  1ZFP E;  1O4D A;  1BLK A;  4P9Z A;  1LUN A;  4JGH A;  3VS7 A;  2IUI A;  1SPR A;  1O4L A;  3VRP A;  4F59 A;  1SHB A;  3S8O A;  1BHH B;  1F2F A;  1FHS A;  4DGX A;  2EYZ A;  4FL3 A;  1LCK A;  1JYU A;  2DX0 A;  2VIF A;  1TZE E;  4OHE A;  3VS1 A;  2PNB A;  3HIZ B;  3OP0 A;  2AUG A;  1OPK A;  4L1B B;  1LKK A;  4XZ1 A;  1BG1 A;  3NHN A;  3BUW B;  2K7A B;  1F1W A;  1O4F A;  5IBM A;  4X6S A;  1MW4 A;  1BFJ A;  1A1A A;  3WA4 A;  1KSW A;  1O4I A;  1O41 A;  3T04 A;  1A1B A;  4DGP A;  2QMS A;  1G83 A;  1MIL A;  3OB1 B;  5D0J A;  4GL9 E;  2ABL A;  3UF4 A;  2IUG A;  3QWX X;  3VRQ A;  4E93 A;  1UUR A;  5J3X A;  3CWG A;  1O48 A;  3CBL A;  1AB2 A;  2B3O A;  2KNO A;  1YVH A;  1AYC A;  2CI9 A;  2EO6 A;  3VS0 A;  3CD3 A;  2CBL A;  4K2R A;  1SKJ A;  1O44 A;  3EAC A;  2IUH A;  1CSZ A;  3M7F A;  3VRZ A;  2FO0 A;  3IMD A;  3N8M A;  1B47 A;  1P13 A;  2OZO A;  1O4A A;  3PJP A;  5KAZ A;  1O4C A;  1M61 A;  1X27 A;  2HCK A;  1CWD L;  2DCR A;  1D4T A;  2EO3 A;  2RSY A;  1AOT F;  2ROR A;  3GQI B;  4EIH A;  1BFI A;  1O4N A;  5HKW A;  1OO3 A;  2LNW A;  1O45 A;  1Z3K A;  4F5A A;  1A08 A;  1WQU A;  5DC9 A;  2YSX A;  1X0N A;  2EKX A;  3QWY A;  1JYR A;  1YVL A;  4OHH A;  1CWE A;  3BUX B;  3HHM B;  2HDX A;  2H5K A;  3VS6 A;  2DVJ A;  1IS0 A;  1R1S A;  2C0T A;  5EEL A;  4K44 A;  1FYR A;  3VS3 A;  1PIC A;  2DM0 A;  2FCI A;  2LQW A;  4LUE A;  3BKB A;  1QAD A;  1O4P A;  3HCK A;  1A07 A;  2HMH A;  4A4B A;  3CXL A;  2GE9 A;  2H46 E;  5EEQ A;  1D1Z A;  3IMJ A;  1GHU A;  2KK6 A;  2H8H A;  4WWQ A;  1RJA A;  3VGO A;  1Y1U A;  1OO4 A;  1HCS B;  1AYA A;  1SPS A;  5IBS A;  1KC2 A;  5EG3 B;  2LQN A;  2C0O A;  1O4M A;  3VS4 A;  4F5B A;  2PNA A;  1AOU F;  1SHD A;  1O4E A;  1A1C A;  2CR4 A;  2EYV A;  2L4K A;  4K11 A;  3IN8 A;  1XA6 A;  2HUW A;  3PS5 A;  3S8N A;  1SHA A;  5I6V A;  2K79 B;  3KFJ A;  1FU6 A;  4A4C A;  1O47 A;  3UYO A;  2RVF A;  3VRN A;  1GRI A;  3VRO A;  4M4Z A;  1FBZ A;  3PFV A;  5EHR A;  3N84 A;  1KA7 A;  5AUL A;  1JU5 A;  4NWG A;  4JEG A;  4P9V A;  3OV1 A;  4FBN A;  3GXX A;  1BMB A;  2EL8 A;  1LUK A;  2BBU A;  3GXW A;  3PLF B;  1LUI A;  1O4K A;  5DF6 A;  2EOB A;  5DC0 B;  3N7Y A;  3BUN B;  4H34 A;  4XZ0 A;  1LCJ A;  2CRH A;  1O4R A;  1A09 A;  2DLZ A;  1NZV A;  1O4B A;  2JYQ A;  2CS0 A;  2MQI A;  2RMX A;  1JYQ A;  2LNX A;  2Y1M A;  4OHI A;  2YU7 A;  1HCT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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