1O4LA

Crystal structure of sh2 in complex with fragment2.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4lA00
2PNBA 2MQIA 3VRPA 2YSXA 2EOBA 1LCJA 3NHNA 1BLJA 5AXIA 4OHIA 3PS5A 1TZEE 3VS1A 1R1SA 1NZVA 1RQQC 2RMXA 2IUGA 4H34A 1YVLA 1NRVA 1O47A 3VRNA 3S8LA 1A1CA 2ETZA 1BFJA 4GWFA 3VS2A 1ZFPE 4LUDA 2LQNA 4E68A 2DCRA 1OO3A 1X0NA 1O4QA 3PSJA 3VRRA 2C0OA 1O46A 1AOUF 1NZLA 2CBLA 1LKLA 1O44A 3PJPA 3GXWA 4OHEA 4XZ1A 1BFIA 4D8KA 2PTKA 1SHAA 2ABLA 1LKKA 1O4BA 1O4RA 2AOBA 3UF4A 4WWQA 5DF6A 1JU5A 1A08A 1SPRA 3BUOB 1AOTF 5GJIA 1O4PA 3EAZA 5EELA 4OHLA 1SHDA 3BKBA 5AULA 4OHHA 4F5AA 5HKWA 5DC0B 3OB2B 4P9VA 2HCKA 2EYZA 2HDXA 3C7IA 2OZOA 1HCTB 1BLKA 1A81A 2DLYA 1R1PA 1F2FA 5D0JA 4JE4A 5CDWA 1O43A 4U1PA 5HKYA 1OPKA 2LCTA 1KSWA 2Y1MA 1KC2A 2DVJA 2LNWA 5EHRA 3CWGA 3WA4A 1PICA 2IUHA 2HMHA 2PLDA 1D1ZA 3US4A 5GJHA 1G83A 1Y57A 2RVFA 4EIHA 2GE9A 1CSYA 4FBNA 1CSZA 1O4DA 2YU7A 2C0TA 1TCEA 3M7FA 1O4MA 1GHUA 3MXCA 3QWYA 4XZ0A 3K2MA 4K44A 3HHMB 1AD5A 2L3TA 1O4IA 2EO6A 3IN7A 4GPLB 5KAZA 1O4FA 1RJAA 3PLFB 1JYUA 2PNAA 2QMSA 1O4JA 1QADA 1A1BA 1QG1E 2KK6A 1OO4A 1IS0A 3ZNIA 1BHFA 4FL3A 4P9ZA 2EKXA 1FBZA 3PFVA 3TL0A 1KA7A 4F59A 3KFJA 1O4LA 1LCKA 2CIAA 2CI8A 2CRHA 1IJRA 2DM0A 2AOAA 4NWFA 3MXYA 3GXXA 2CS0A 1P13A 1K9AA 4JEGA 1AYDA 3OP0A 5EG3B 3IMDA 5I6VA 1SKJA 1BHHB 2BBUA 1D4TA 2EYYA 1BKLA 1O49A 2XP1A 1BF5A 1LUIA 2OQ1A 2C9WA 3VRZA 1X6CA 2GSBA 1SPSA 3OV1A 1M27A 3VRQA 3VS6A 4DGXA 2MK2A 1FYRA 2RORA 4DGPA 3CXLA 3QWXX 1FU6A 1F1WA 3BUWB 1FMKA 4L1BB 3VGOA 2EO3A 3S8NA 2JYQA 1D4WA 1O42A 1FBVA 1LUNA 4K45A 1KA6A 2SRCA 3MAZA 1FU5A 3CD3A 4K2RA 5IBMA 1O4GA 5BO4A 1O4HA 2LNXA 1AYAA 2HUWA 2KNOA 4X6SA 1Y1UA 1A1AA 4F5BA 2MRJA 2HDVA 1HCSB 3GQIB 3S8OA 4NWGA 1A1EA 3UYOA 3T04A 4JGHA 1BMBA 2MC1A 2FCIA 3CBLA 3HIZB 3OVEA 3S9KA 1O48A 2EYVA 2CI9A 4OHDA 4TZIA 2PLEA 2Y1NA 1BM2A 4FL2A 3N84A 5DC9A 1BKMA 1SHBA 2IUIA 4U17A 1UURA 1JYRA 3EACA 2H5KA 1Z3KA 1RPYA 3N8MA 2H8HA 2FO0A 2VIFA 3VS7A 5HKZA 1A07A 1BHHA 2L4KA 1MW4A 3HCKA 2SHPA 3PQZA 3VS4A 5DC4A 2C0IA 4H1OA 1B47A 1M61A 2LQWA 1GRIA 4K11A 2DLZA 3OB1B 1O41A 2RSYA 4M4ZA 2H46E 1O45A 1AYCA 1WQUA 1CWDL 3TKZA 1CJ1A 3VS5A 5J3XA 1O4NA 1OPLA 5EHPA 1BG1A 1AB2A 1H9OA 1A09A 2K7AB 3VS0A 1FHSA 4A4CA 2Y3AB 2CR4A 4LUEA 5EEQA 5IBSA 2MRKA 2ECDA 2DX0A 4QSYA 1I3ZA 2IZVA 3VS3A 1XA6A 1QCFA 3BUXB 1UUSA 1AYBA 4E93A 1YVHA 1O4OA 1CWEA 1X27A 1O4CA 2AUGA 3IMJA 4EY0A 2EU0A 3IN8A 3VROA 1JWOA 3N7YA 2K79B 1MILA 1O4KA 4GL9E 3VRYA 2EL8A 2B3OA 1LUKA 1JYQA 1LUMA 1O4AA 3PSKA 2L6KA 1O4EA 4ROJA 3BUNB 3BUMB 1R1QA 4A4BA
chains in the Genus database with same CATH superfamily
2PNBA 2MQIA 3VRPA 2YSXA 2EOBA 1LCJA 3NHNA 1BLJA 5AXIA 4OHIA 3PS5A 1TZEE 3VS1A 1R1SA 1NZVA 1RQQC 2RMXA 2IUGA 4H34A 1YVLA 1NRVA 1O47A 3VRNA 3S8LA 1A1CA 2ETZA 1BFJA 4GWFA 3VS2A 1ZFPE 4LUDA 2LQNA 4E68A 2DCRA 1OO3A 1X0NA 1O4QA 3PSJA 3VRRA 2C0OA 1O46A 1AOUF 1NZLA 2CBLA 1LKLA 1O44A 3PJPA 3GXWA 4OHEA 4XZ1A 1BFIA 4D8KA 2KGYA 2PTKA 1SHAA 2ABLA 1LKKA 1O4BA 1O4RA 2AOBA 3UF4A 4WWQA 5DF6A 1JU5A 1A08A 1SPRA 3BUOB 1AOTF 5GJIA 1O4PA 3EAZA 3LYVA 5EELA 4OHLA 1SHDA 3BKBA 5AULA 4OHHA 4F5AA 5HKWA 5DC0B 3OB2B 4P9VA 2HCKA 2EYZA 2HDXA 3C7IA 2OZOA 1HCTB 1BLKA 1A81A 2DLYA 1R1PA 1F2FA 5D0JA 4JE4A 5CDWA 1O43A 4U1PA 5HKYA 1OPKA 2LCTA 1KSWA 2Y1MA 1KC2A 2DVJA 2LNWA 5EHRA 3CWGA 3WA4A 1PICA 2IUHA 2HMHA 2PLDA 1D1ZA 3US4A 5GJHA 1G83A 1Y57A 2RVFA 4EIHA 2GE9A 1CSYA 4FBNA 1CSZA 1O4DA 2YU7A 2C0TA 1TCEA 3M7FA 1O4MA 1GHUA 3MXCA 3QWYA 4XZ0A 3K2MA 4K44A 3HHMB 1AD5A 2L3TA 1O4IA 2EO6A 3IN7A 4GPLB 5KAZA 1O4FA 1RJAA 3PLFB 2LRAA 1JYUA 2PNAA 2QMSA 1O4JA 1QADA 1A1BA 1QG1E 2KK6A 1OO4A 1IS0A 3ZNIA 1BHFA 4FL3A 4P9ZA 2EKXA 1FBZA 3PFVA 3TL0A 1KA7A 4F59A 3KFJA 1O4LA 1LCKA 2CIAA 2CI8A 2CRHA 1IJRA 2DM0A 2AOAA 4NWFA 3MXYA 3K2TA 3GXXA 2CS0A 1P13A 1K9AA 4JEGA 1AYDA 3OP0A 5EG3B 3IMDA 5I6VA 1SKJA 1BHHB 2BBUA 1D4TA 2EYYA 1BKLA 1O49A 2XP1A 1BF5A 1LUIA 2OQ1A 2C9WA 3VRZA 1X6CA 2GSBA 1SPSA 3OV1A 1M27A 3VRQA 3VS6A 4DGXA 2MK2A 1FYRA 2RORA 4DGPA 3CXLA 3QWXX 1FU6A 1F1WA 3BUWB 1FMKA 4L1BB 3VGOA 2EO3A 3S8NA 2JYQA 1D4WA 1O42A 1FBVA 1LUNA 4K45A 1KA6A 2SRCA 3MAZA 1FU5A 3CD3A 4K2RA 5IBMA 1O4GA 5BO4A 1O4HA 2LNXA 1AYAA 2HUWA 2KNOA 4X6SA 1Y1UA 1A1AA 4F5BA 2MRJA 2HDVA 1HCSB 3GQIB 3S8OA 4NWGA 1A1EA 3UYOA 3T04A 4JGHA 1BMBA 2MC1A 2FCIA 3CBLA 3HIZB 3OVEA 3S9KA 1O48A 2EYVA 2CI9A 4OHDA 4TZIA 2PLEA 2Y1NA 1BM2A 4FL2A 3N84A 5DC9A 1BKMA 1SHBA 2IUIA 4U17A 1UURA 1JYRA 3EACA 2H5KA 1Z3KA 1RPYA 3N8MA 2H8HA 2FO0A 2VIFA 3VS7A 5HKZA 1A07A 1BHHA 2L4KA 1MW4A 3HCKA 2SHPA 3PQZA 3VS4A 5DC4A 2C0IA 4H1OA 1B47A 1M61A 2LQWA 1GRIA 4K11A 2DLZA 3OB1B 1O41A 2RSYA 4M4ZA 2H46E 1O45A 1AYCA 1WQUA 1CWDL 3TKZA 1CJ1A 3VS5A 5J3XA 1O4NA 1OPLA 5EHPA 1BG1A 1AB2A 1H9OA 1A09A 2K7AB 3VS0A 1FHSA 4A4CA 2Y3AB 2CR4A 4LUEA 5EEQA 5IBSA 2MRKA 2ECDA 2DX0A 4QSYA 1I3ZA 2IZVA 3VS3A 1XA6A 1QCFA 3BUXB 1UUSA 1AYBA 4E93A 1YVHA 1O4OA 1CWEA 1X27A 1O4CA 2AUGA 3IMJA 4EY0A 2EU0A 3IN8A 3VROA 1JWOA 3N7YA 2K79B 1MILA 1O4KA 4GL9E 3VRYA 2EL8A 2B3OA 1LUKA 1JYQA 1LUMA 1O4AA 3PSKA 2L6KA 1O4EA 4ROJA 3BUNB 3BUMB 1R1QA 4A4BA
chains in the Genus database with same CATH topology
2PNBA 2MQIA 3VRPA 2YSXA 2EOBA 1LCJA 3NHNA 1BLJA 5AXIA 4OHIA 3PS5A 1TZEE 3VS1A 1R1SA 1NZVA 1RQQC 2RMXA 2IUGA 4H34A 1YVLA 1NRVA 1O47A 3VRNA 3S8LA 1A1CA 2ETZA 1BFJA 4GWFA 3VS2A 1ZFPE 4LUDA 2LQNA 4E68A 2DCRA 1OO3A 1X0NA 1O4QA 3PSJA 3VRRA 2C0OA 1O46A 1AOUF 1NZLA 2CBLA 1LKLA 1O44A 3PJPA 3GXWA 4OHEA 4XZ1A 1BFIA 4D8KA 2PTKA 1SHAA 2ABLA 1LKKA 1O4BA 1O4RA 2AOBA 3UF4A 4WWQA 5DF6A 1JU5A 1A08A 1SPRA 3BUOB 1AOTF 5GJIA 1O4PA 3EAZA 5EELA 4OHLA 1SHDA 3BKBA 5AULA 4OHHA 4F5AA 5HKWA 5DC0B 3OB2B 4P9VA 2HCKA 2EYZA 2HDXA 3C7IA 2OZOA 1HCTB 1BLKA 1A81A 2DLYA 1R1PA 1F2FA 5D0JA 4JE4A 5CDWA 1O43A 4U1PA 5HKYA 1OPKA 2LCTA 1KSWA 2Y1MA 1KC2A 2DVJA 2LNWA 5EHRA 3CWGA 3WA4A 1PICA 2IUHA 2HMHA 2PLDA 1D1ZA 3US4A 5GJHA 1G83A 1Y57A 2RVFA 4EIHA 2GE9A 1CSYA 4FBNA 1CSZA 1O4DA 2YU7A 2C0TA 1TCEA 3M7FA 1O4MA 1GHUA 3MXCA 3QWYA 4XZ0A 3K2MA 4K44A 3HHMB 1AD5A 2L3TA 1O4IA 2EO6A 3IN7A 4GPLB 5KAZA 1O4FA 1RJAA 3PLFB 1JYUA 2PNAA 2QMSA 1O4JA 1QADA 1A1BA 1QG1E 2KK6A 1OO4A 1IS0A 3ZNIA 1BHFA 4FL3A 4P9ZA 2EKXA 1FBZA 3PFVA 3TL0A 1KA7A 4F59A 3KFJA 1O4LA 1LCKA 2CIAA 2CI8A 2CRHA 1IJRA 2DM0A 2AOAA 4NWFA 3MXYA 3GXXA 2CS0A 1P13A 1K9AA 4JEGA 1AYDA 3OP0A 5EG3B 3IMDA 5I6VA 1SKJA 1BHHB 2BBUA 1D4TA 2EYYA 1BKLA 1O49A 2XP1A 1BF5A 1LUIA 2OQ1A 2C9WA 3VRZA 1X6CA 2GSBA 1SPSA 3OV1A 1M27A 3VRQA 3VS6A 4DGXA 2MK2A 1FYRA 2RORA 4DGPA 3CXLA 3QWXX 1FU6A 1F1WA 3BUWB 1FMKA 4L1BB 3VGOA 2EO3A 3S8NA 2JYQA 1D4WA 1O42A 1FBVA 1LUNA 4K45A 1KA6A 2SRCA 3MAZA 1FU5A 3CD3A 4K2RA 5IBMA 1O4GA 5BO4A 1O4HA 2LNXA 1AYAA 2HUWA 2KNOA 4X6SA 1Y1UA 1A1AA 4F5BA 2MRJA 2HDVA 1HCSB 3GQIB 3S8OA 4NWGA 1A1EA 3UYOA 3T04A 4JGHA 1BMBA 2MC1A 2FCIA 3CBLA 3HIZB 3OVEA 3S9KA 1O48A 2EYVA 2CI9A 4OHDA 4TZIA 2PLEA 2Y1NA 1BM2A 4FL2A 3N84A 5DC9A 1BKMA 1SHBA 2IUIA 4U17A 1UURA 1JYRA 3EACA 2H5KA 1Z3KA 1RPYA 3N8MA 2H8HA 2FO0A 2VIFA 3VS7A 5HKZA 1A07A 1BHHA 2L4KA 1MW4A 3HCKA 2SHPA 3PQZA 3VS4A 5DC4A 2C0IA 4H1OA 1B47A 1M61A 2LQWA 1GRIA 4K11A 2DLZA 3OB1B 1O41A 2RSYA 4M4ZA 2H46E 1O45A 1AYCA 1WQUA 1CWDL 3TKZA 1CJ1A 3VS5A 5J3XA 1O4NA 1OPLA 5EHPA 1BG1A 1AB2A 1H9OA 1A09A 2K7AB 3VS0A 1FHSA 4A4CA 2Y3AB 2CR4A 4LUEA 5EEQA 5IBSA 2MRKA 2ECDA 2DX0A 4QSYA 1I3ZA 2IZVA 3VS3A 1XA6A 1QCFA 3BUXB 1UUSA 1AYBA 4E93A 1YVHA 1O4OA 1CWEA 1X27A 1O4CA 2AUGA 3IMJA 4EY0A 2EU0A 3IN8A 3VROA 1JWOA 3N7YA 2K79B 1MILA 1O4KA 4GL9E 3VRYA 2EL8A 2B3OA 1LUKA 1JYQA 1LUMA 1O4AA 3PSKA 2L6KA 1O4EA 4ROJA 3BUNB 3BUMB 1R1QA 4A4BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PNB A;  2MQI A;  3VRP A;  2YSX A;  2EOB A;  1LCJ A;  3NHN A;  1BLJ A;  5AXI A;  4OHI A;  3PS5 A;  1TZE E;  3VS1 A;  1R1S A;  1NZV A;  1RQQ C;  2RMX A;  2IUG A;  4H34 A;  1YVL A;  1NRV A;  1O47 A;  3VRN A;  3S8L A;  1A1C A;  2ETZ A;  1BFJ A;  4GWF A;  3VS2 A;  1ZFP E;  4LUD A;  2LQN A;  4E68 A;  2DCR A;  1OO3 A;  1X0N A;  1O4Q A;  3PSJ A;  3VRR A;  2C0O A;  1O46 A;  1AOU F;  1NZL A;  2CBL A;  1LKL A;  1O44 A;  3PJP A;  3GXW A;  4OHE A;  4XZ1 A;  1BFI A;  4D8K A;  2PTK A;  1SHA A;  2ABL A;  1LKK A;  1O4B A;  1O4R A;  2AOB A;  3UF4 A;  4WWQ A;  5DF6 A;  1JU5 A;  1A08 A;  1SPR A;  3BUO B;  1AOT F;  5GJI A;  1O4P A;  3EAZ A;  5EEL A;  4OHL A;  1SHD A;  3BKB A;  5AUL A;  4OHH A;  4F5A A;  5HKW A;  5DC0 B;  3OB2 B;  4P9V A;  2HCK A;  2EYZ A;  2HDX A;  3C7I A;  2OZO A;  1HCT B;  1BLK A;  1A81 A;  2DLY A;  1R1P A;  1F2F A;  5D0J A;  4JE4 A;  5CDW A;  1O43 A;  4U1P A;  5HKY A;  1OPK A;  2LCT A;  1KSW A;  2Y1M A;  1KC2 A;  2DVJ A;  2LNW A;  5EHR A;  3CWG A;  3WA4 A;  1PIC A;  2IUH A;  2HMH A;  2PLD A;  1D1Z A;  3US4 A;  5GJH A;  1G83 A;  1Y57 A;  2RVF A;  4EIH A;  2GE9 A;  1CSY A;  4FBN A;  1CSZ A;  1O4D A;  2YU7 A;  2C0T A;  1TCE A;  3M7F A;  1O4M A;  1GHU A;  3MXC A;  3QWY A;  4XZ0 A;  3K2M A;  4K44 A;  3HHM B;  1AD5 A;  2L3T A;  1O4I A;  2EO6 A;  3IN7 A;  4GPL B;  5KAZ A;  1O4F A;  1RJA A;  3PLF B;  1JYU A;  2PNA A;  2QMS A;  1O4J A;  1QAD A;  1A1B A;  1QG1 E;  2KK6 A;  1OO4 A;  1IS0 A;  3ZNI A;  1BHF A;  4FL3 A;  4P9Z A;  2EKX A;  1FBZ A;  3PFV A;  3TL0 A;  1KA7 A;  4F59 A;  3KFJ A;  1O4L A;  1LCK A;  2CIA A;  2CI8 A;  2CRH A;  1IJR A;  2DM0 A;  2AOA A;  4NWF A;  3MXY A;  3GXX A;  2CS0 A;  1P13 A;  1K9A A;  4JEG A;  1AYD A;  3OP0 A;  5EG3 B;  3IMD A;  5I6V A;  1SKJ A;  1BHH B;  2BBU A;  1D4T A;  2EYY A;  1BKL A;  1O49 A;  2XP1 A;  1BF5 A;  1LUI A;  2OQ1 A;  2C9W A;  3VRZ A;  1X6C A;  2GSB A;  1SPS A;  3OV1 A;  1M27 A;  3VRQ A;  3VS6 A;  4DGX A;  2MK2 A;  1FYR A;  2ROR A;  4DGP A;  3CXL A;  3QWX X;  1FU6 A;  1F1W A;  3BUW B;  1FMK A;  4L1B B;  3VGO A;  2EO3 A;  3S8N A;  2JYQ A;  1D4W A;  1O42 A;  1FBV A;  1LUN A;  4K45 A;  1KA6 A;  2SRC A;  3MAZ A;  1FU5 A;  3CD3 A;  4K2R A;  5IBM A;  1O4G A;  5BO4 A;  1O4H A;  2LNX A;  1AYA A;  2HUW A;  2KNO A;  4X6S A;  1Y1U A;  1A1A A;  4F5B A;  2MRJ A;  2HDV A;  1HCS B;  3GQI B;  3S8O A;  4NWG A;  1A1E A;  3UYO A;  3T04 A;  4JGH A;  1BMB A;  2MC1 A;  2FCI A;  3CBL A;  3HIZ B;  3OVE A;  3S9K A;  1O48 A;  2EYV A;  2CI9 A;  4OHD A;  4TZI A;  2PLE A;  2Y1N A;  1BM2 A;  4FL2 A;  3N84 A;  5DC9 A;  1BKM A;  1SHB A;  2IUI A;  4U17 A;  1UUR A;  1JYR A;  3EAC A;  2H5K A;  1Z3K A;  1RPY A;  3N8M A;  2H8H A;  2FO0 A;  2VIF A;  3VS7 A;  5HKZ A;  1A07 A;  1BHH A;  2L4K A;  1MW4 A;  3HCK A;  2SHP A;  3PQZ A;  3VS4 A;  5DC4 A;  2C0I A;  4H1O A;  1B47 A;  1M61 A;  2LQW A;  1GRI A;  4K11 A;  2DLZ A;  3OB1 B;  1O41 A;  2RSY A;  4M4Z A;  2H46 E;  1O45 A;  1AYC A;  1WQU A;  1CWD L;  3TKZ A;  1CJ1 A;  3VS5 A;  5J3X A;  1O4N A;  1OPL A;  5EHP A;  1BG1 A;  1AB2 A;  1H9O A;  1A09 A;  2K7A B;  3VS0 A;  1FHS A;  4A4C A;  2Y3A B;  2CR4 A;  4LUE A;  5EEQ A;  5IBS A;  2MRK A;  2ECD A;  2DX0 A;  4QSY A;  1I3Z A;  2IZV A;  3VS3 A;  1XA6 A;  1QCF A;  3BUX B;  1UUS A;  1AYB A;  4E93 A;  1YVH A;  1O4O A;  1CWE A;  1X27 A;  1O4C A;  2AUG A;  3IMJ A;  4EY0 A;  2EU0 A;  3IN8 A;  3VRO A;  1JWO A;  3N7Y A;  2K79 B;  1MIL A;  1O4K A;  4GL9 E;  3VRY A;  2EL8 A;  2B3O A;  1LUK A;  1JYQ A;  1LUM A;  1O4A A;  3PSK A;  2L6K A;  1O4E A;  4ROJ A;  3BUN B;  3BUM B;  1R1Q A;  4A4B A; 
#chains in the Genus database with same CATH topology
 2PNB A;  2MQI A;  3VRP A;  2YSX A;  2EOB A;  1LCJ A;  3NHN A;  1BLJ A;  5AXI A;  4OHI A;  3PS5 A;  1TZE E;  3VS1 A;  1R1S A;  1NZV A;  1RQQ C;  2RMX A;  2IUG A;  4H34 A;  1YVL A;  1NRV A;  1O47 A;  3VRN A;  3S8L A;  1A1C A;  2ETZ A;  1BFJ A;  4GWF A;  3VS2 A;  1ZFP E;  4LUD A;  2LQN A;  4E68 A;  2DCR A;  1OO3 A;  1X0N A;  1O4Q A;  3PSJ A;  3VRR A;  2C0O A;  1O46 A;  1AOU F;  1NZL A;  2CBL A;  1LKL A;  1O44 A;  3PJP A;  3GXW A;  4OHE A;  4XZ1 A;  1BFI A;  4D8K A;  2KGY A;  2PTK A;  1SHA A;  2ABL A;  1LKK A;  1O4B A;  1O4R A;  2AOB A;  3UF4 A;  4WWQ A;  5DF6 A;  1JU5 A;  1A08 A;  1SPR A;  3BUO B;  1AOT F;  5GJI A;  1O4P A;  3EAZ A;  3LYV A;  5EEL A;  4OHL A;  1SHD A;  3BKB A;  5AUL A;  4OHH A;  4F5A A;  5HKW A;  5DC0 B;  3OB2 B;  4P9V A;  2HCK A;  2EYZ A;  2HDX A;  3C7I A;  2OZO A;  1HCT B;  1BLK A;  1A81 A;  2DLY A;  1R1P A;  1F2F A;  5D0J A;  4JE4 A;  5CDW A;  1O43 A;  4U1P A;  5HKY A;  1OPK A;  2LCT A;  1KSW A;  2Y1M A;  1KC2 A;  2DVJ A;  2LNW A;  5EHR A;  3CWG A;  3WA4 A;  1PIC A;  2IUH A;  2HMH A;  2PLD A;  1D1Z A;  3US4 A;  5GJH A;  1G83 A;  1Y57 A;  2RVF A;  4EIH A;  2GE9 A;  1CSY A;  4FBN A;  1CSZ A;  1O4D A;  2YU7 A;  2C0T A;  1TCE A;  3M7F A;  1O4M A;  1GHU A;  3MXC A;  3QWY A;  4XZ0 A;  3K2M A;  4K44 A;  3HHM B;  1AD5 A;  2L3T A;  1O4I A;  2EO6 A;  3IN7 A;  4GPL B;  5KAZ A;  1O4F A;  1RJA A;  3PLF B;  2LRA A;  1JYU A;  2PNA A;  2QMS A;  1O4J A;  1QAD A;  1A1B A;  1QG1 E;  2KK6 A;  1OO4 A;  1IS0 A;  3ZNI A;  1BHF A;  4FL3 A;  4P9Z A;  2EKX A;  1FBZ A;  3PFV A;  3TL0 A;  1KA7 A;  4F59 A;  3KFJ A;  1O4L A;  1LCK A;  2CIA A;  2CI8 A;  2CRH A;  1IJR A;  2DM0 A;  2AOA A;  4NWF A;  3MXY A;  3K2T A;  3GXX A;  2CS0 A;  1P13 A;  1K9A A;  4JEG A;  1AYD A;  3OP0 A;  5EG3 B;  3IMD A;  5I6V A;  1SKJ A;  1BHH B;  2BBU A;  1D4T A;  2EYY A;  1BKL A;  1O49 A;  2XP1 A;  1BF5 A;  1LUI A;  2OQ1 A;  2C9W A;  3VRZ A;  1X6C A;  2GSB A;  1SPS A;  3OV1 A;  1M27 A;  3VRQ A;  3VS6 A;  4DGX A;  2MK2 A;  1FYR A;  2ROR A;  4DGP A;  3CXL A;  3QWX X;  1FU6 A;  1F1W A;  3BUW B;  1FMK A;  4L1B B;  3VGO A;  2EO3 A;  3S8N A;  2JYQ A;  1D4W A;  1O42 A;  1FBV A;  1LUN A;  4K45 A;  1KA6 A;  2SRC A;  3MAZ A;  1FU5 A;  3CD3 A;  4K2R A;  5IBM A;  1O4G A;  5BO4 A;  1O4H A;  2LNX A;  1AYA A;  2HUW A;  2KNO A;  4X6S A;  1Y1U A;  1A1A A;  4F5B A;  2MRJ A;  2HDV A;  1HCS B;  3GQI B;  3S8O A;  4NWG A;  1A1E A;  3UYO A;  3T04 A;  4JGH A;  1BMB A;  2MC1 A;  2FCI A;  3CBL A;  3HIZ B;  3OVE A;  3S9K A;  1O48 A;  2EYV A;  2CI9 A;  4OHD A;  4TZI A;  2PLE A;  2Y1N A;  1BM2 A;  4FL2 A;  3N84 A;  5DC9 A;  1BKM A;  1SHB A;  2IUI A;  4U17 A;  1UUR A;  1JYR A;  3EAC A;  2H5K A;  1Z3K A;  1RPY A;  3N8M A;  2H8H A;  2FO0 A;  2VIF A;  3VS7 A;  5HKZ A;  1A07 A;  1BHH A;  2L4K A;  1MW4 A;  3HCK A;  2SHP A;  3PQZ A;  3VS4 A;  5DC4 A;  2C0I A;  4H1O A;  1B47 A;  1M61 A;  2LQW A;  1GRI A;  4K11 A;  2DLZ A;  3OB1 B;  1O41 A;  2RSY A;  4M4Z A;  2H46 E;  1O45 A;  1AYC A;  1WQU A;  1CWD L;  3TKZ A;  1CJ1 A;  3VS5 A;  5J3X A;  1O4N A;  1OPL A;  5EHP A;  1BG1 A;  1AB2 A;  1H9O A;  1A09 A;  2K7A B;  3VS0 A;  1FHS A;  4A4C A;  2Y3A B;  2CR4 A;  4LUE A;  5EEQ A;  5IBS A;  2MRK A;  2ECD A;  2DX0 A;  4QSY A;  1I3Z A;  2IZV A;  3VS3 A;  1XA6 A;  1QCF A;  3BUX B;  1UUS A;  1AYB A;  4E93 A;  1YVH A;  1O4O A;  1CWE A;  1X27 A;  1O4C A;  2AUG A;  3IMJ A;  4EY0 A;  2EU0 A;  3IN8 A;  3VRO A;  1JWO A;  3N7Y A;  2K79 B;  1MIL A;  1O4K A;  4GL9 E;  3VRY A;  2EL8 A;  2B3O A;  1LUK A;  1JYQ A;  1LUM A;  1O4A A;  3PSK A;  2L6K A;  1O4E A;  4ROJ A;  3BUN B;  3BUM B;  1R1Q A;  4A4B A; 
#chains in the Genus database with same CATH homology
 2PNB A;  2MQI A;  3VRP A;  2YSX A;  2EOB A;  1LCJ A;  3NHN A;  1BLJ A;  5AXI A;  4OHI A;  3PS5 A;  1TZE E;  3VS1 A;  1R1S A;  1NZV A;  1RQQ C;  2RMX A;  2IUG A;  4H34 A;  1YVL A;  1NRV A;  1O47 A;  3VRN A;  3S8L A;  1A1C A;  2ETZ A;  1BFJ A;  4GWF A;  3VS2 A;  1ZFP E;  4LUD A;  2LQN A;  4E68 A;  2DCR A;  1OO3 A;  1X0N A;  1O4Q A;  3PSJ A;  3VRR A;  2C0O A;  1O46 A;  1AOU F;  1NZL A;  2CBL A;  1LKL A;  1O44 A;  3PJP A;  3GXW A;  4OHE A;  4XZ1 A;  1BFI A;  4D8K A;  2PTK A;  1SHA A;  2ABL A;  1LKK A;  1O4B A;  1O4R A;  2AOB A;  3UF4 A;  4WWQ A;  5DF6 A;  1JU5 A;  1A08 A;  1SPR A;  3BUO B;  1AOT F;  5GJI A;  1O4P A;  3EAZ A;  5EEL A;  4OHL A;  1SHD A;  3BKB A;  5AUL A;  4OHH A;  4F5A A;  5HKW A;  5DC0 B;  3OB2 B;  4P9V A;  2HCK A;  2EYZ A;  2HDX A;  3C7I A;  2OZO A;  1HCT B;  1BLK A;  1A81 A;  2DLY A;  1R1P A;  1F2F A;  5D0J A;  4JE4 A;  5CDW A;  1O43 A;  4U1P A;  5HKY A;  1OPK A;  2LCT A;  1KSW A;  2Y1M A;  1KC2 A;  2DVJ A;  2LNW A;  5EHR A;  3CWG A;  3WA4 A;  1PIC A;  2IUH A;  2HMH A;  2PLD A;  1D1Z A;  3US4 A;  5GJH A;  1G83 A;  1Y57 A;  2RVF A;  4EIH A;  2GE9 A;  1CSY A;  4FBN A;  1CSZ A;  1O4D A;  2YU7 A;  2C0T A;  1TCE A;  3M7F A;  1O4M A;  1GHU A;  3MXC A;  3QWY A;  4XZ0 A;  3K2M A;  4K44 A;  3HHM B;  1AD5 A;  2L3T A;  1O4I A;  2EO6 A;  3IN7 A;  4GPL B;  5KAZ A;  1O4F A;  1RJA A;  3PLF B;  1JYU A;  2PNA A;  2QMS A;  1O4J A;  1QAD A;  1A1B A;  1QG1 E;  2KK6 A;  1OO4 A;  1IS0 A;  3ZNI A;  1BHF A;  4FL3 A;  4P9Z A;  2EKX A;  1FBZ A;  3PFV A;  3TL0 A;  1KA7 A;  4F59 A;  3KFJ A;  1O4L A;  1LCK A;  2CIA A;  2CI8 A;  2CRH A;  1IJR A;  2DM0 A;  2AOA A;  4NWF A;  3MXY A;  3GXX A;  2CS0 A;  1P13 A;  1K9A A;  4JEG A;  1AYD A;  3OP0 A;  5EG3 B;  3IMD A;  5I6V A;  1SKJ A;  1BHH B;  2BBU A;  1D4T A;  2EYY A;  1BKL A;  1O49 A;  2XP1 A;  1BF5 A;  1LUI A;  2OQ1 A;  2C9W A;  3VRZ A;  1X6C A;  2GSB A;  1SPS A;  3OV1 A;  1M27 A;  3VRQ A;  3VS6 A;  4DGX A;  2MK2 A;  1FYR A;  2ROR A;  4DGP A;  3CXL A;  3QWX X;  1FU6 A;  1F1W A;  3BUW B;  1FMK A;  4L1B B;  3VGO A;  2EO3 A;  3S8N A;  2JYQ A;  1D4W A;  1O42 A;  1FBV A;  1LUN A;  4K45 A;  1KA6 A;  2SRC A;  3MAZ A;  1FU5 A;  3CD3 A;  4K2R A;  5IBM A;  1O4G A;  5BO4 A;  1O4H A;  2LNX A;  1AYA A;  2HUW A;  2KNO A;  4X6S A;  1Y1U A;  1A1A A;  4F5B A;  2MRJ A;  2HDV A;  1HCS B;  3GQI B;  3S8O A;  4NWG A;  1A1E A;  3UYO A;  3T04 A;  4JGH A;  1BMB A;  2MC1 A;  2FCI A;  3CBL A;  3HIZ B;  3OVE A;  3S9K A;  1O48 A;  2EYV A;  2CI9 A;  4OHD A;  4TZI A;  2PLE A;  2Y1N A;  1BM2 A;  4FL2 A;  3N84 A;  5DC9 A;  1BKM A;  1SHB A;  2IUI A;  4U17 A;  1UUR A;  1JYR A;  3EAC A;  2H5K A;  1Z3K A;  1RPY A;  3N8M A;  2H8H A;  2FO0 A;  2VIF A;  3VS7 A;  5HKZ A;  1A07 A;  1BHH A;  2L4K A;  1MW4 A;  3HCK A;  2SHP A;  3PQZ A;  3VS4 A;  5DC4 A;  2C0I A;  4H1O A;  1B47 A;  1M61 A;  2LQW A;  1GRI A;  4K11 A;  2DLZ A;  3OB1 B;  1O41 A;  2RSY A;  4M4Z A;  2H46 E;  1O45 A;  1AYC A;  1WQU A;  1CWD L;  3TKZ A;  1CJ1 A;  3VS5 A;  5J3X A;  1O4N A;  1OPL A;  5EHP A;  1BG1 A;  1AB2 A;  1H9O A;  1A09 A;  2K7A B;  3VS0 A;  1FHS A;  4A4C A;  2Y3A B;  2CR4 A;  4LUE A;  5EEQ A;  5IBS A;  2MRK A;  2ECD A;  2DX0 A;  4QSY A;  1I3Z A;  2IZV A;  3VS3 A;  1XA6 A;  1QCF A;  3BUX B;  1UUS A;  1AYB A;  4E93 A;  1YVH A;  1O4O A;  1CWE A;  1X27 A;  1O4C A;  2AUG A;  3IMJ A;  4EY0 A;  2EU0 A;  3IN8 A;  3VRO A;  1JWO A;  3N7Y A;  2K79 B;  1MIL A;  1O4K A;  4GL9 E;  3VRY A;  2EL8 A;  2B3O A;  1LUK A;  1JYQ A;  1LUM A;  1O4A A;  3PSK A;  2L6K A;  1O4E A;  4ROJ A;  3BUN B;  3BUM B;  1R1Q A;  4A4B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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