1O4MA

Crystal structure of sh2 in complex with malonicacid.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 27
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4mA00
3N8MA 4FBNA 1FYRA 1A08A 3PSJA 1O4BA 1X27A 1NRVA 1LKKA 2C0OA 3CBLA 3CXLA 3QWYA 4F5AA 3VGOA 2EO6A 3TKZA 3VS4A 1SPSA 3TL0A 1A1BA 1HCTB 2EKXA 1TCEA 3VS2A 1H9OA 4JGHA 3HHMB 1I3ZA 2MRJA 1Z3KA 3CD3A 1R1SA 1NZLA 2HCKA 1A1EA 2EYZA 3N84A 1B47A 1O4QA 2L4KA 1CSYA 5AXIA 2CI9A 2OQ1A 3S8NA 4QSYA 1O48A 5DF6A 1AYAA 1GRIA 1BLJA 2EYVA 2DVJA 4GWFA 2B3OA 2Y1NA 1O47A 2Y3AB 1F1WA 3IN7A 1O4LA 3PLFB 2LNXA 3EAZA 2HUWA 1O4OA 2PLEA 1SPRA 2MRKA 1OO4A 4DGXA 1AYDA 2IUIA 4U17A 1A09A 3HIZB 3BUOB 4LUDA 2SHPA 5IBSA 1FHSA 3IMDA 4OHHA 2PNBA 1O4IA 1M27A 4A4BA 2LQWA 2JYQA 4H34A 2PLDA 1O43A 2CI8A 2GSBA 3C7IA 3GQIB 1MW4A 4EY0A 4H1OA 2VIFA 3VS7A 4DGPA 1LUMA 2LQNA 3VS1A 3ZNIA 1O4FA 2HDVA 3MAZA 1LUNA 3KFJA 2DCRA 1JU5A 3VS6A 5KAZA 1BG1A 3VRPA 3UF4A 3VRYA 1FMKA 4ROJA 1AYBA 1K9AA 4EIHA 2IZVA 5EHRA 4M4ZA 3WA4A 3VRNA 5CDWA 1QCFA 5BO4A 2LNWA 1OPLA 3VRZA 2AOAA 1BF5A 1BHFA 2DM0A 2DLZA 1BLKA 1AYCA 1WQUA 2CRHA 2CR4A 1FU5A 1RPYA 1HCSB 1O41A 1LKLA 1SHAA 4FL3A 2EYYA 4FL2A 1O49A 3VS3A 2ABLA 1O4KA 3K2MA 3PFVA 1O46A 4JE4A 1FU6A 5HKZA 4L1BB 3S9KA 4F5BA 1D4TA 3NHNA 3PSKA 2RVFA 5HKYA 5AULA 1IS0A 5D0JA 1O4EA 1CSZA 2KNOA 5I6VA 3BUMB 4D8KA 1O45A 4U1PA 2PNAA 3BUWB 4P9ZA 1JYQA 5DC4A 4XZ0A 2MQIA 2K79B 3VRQA 1O4DA 1PICA 4K2RA 4K11A 2EL8A 2EO3A 3VRRA 1CWDL 3EACA 3QWXX 1Y1UA 3BKBA 3M7FA 1BHHA 1O4MA 4E93A 1UURA 1LCKA 1A81A 2C0TA 2SRCA 1BFJA 1KSWA 2QMSA 1CJ1A 5IBMA 2IUGA 4E68A 2LCTA 1XA6A 1JYRA 1FBVA 1BKMA 4OHDA 4K44A 4TZIA 3VROA 2PTKA 1UUSA 5GJIA 2RMXA 3OVEA 1BM2A 1M61A 4OHLA 3MXYA 3OV1A 5DC0B 3IN8A 1BKLA 3N7YA 1AD5A 1NZVA 1SHBA 3T04A 1R1PA 2DX0A 1KA7A 1O4AA 1SKJA 2Y1MA 5DC9A 3MXCA 2C0IA 4P9VA 1RQQC 3BUNB 1O4PA 2CIAA 2FCIA 1TZEE 1O42A 4GL9E 2CBLA 3GXXA 1ZFPE 4NWGA 2H8HA 2HDXA 2CS0A 4GPLB 4OHIA 3VS0A 2FO0A 4OHEA 1X6CA 1O4HA 1LCJA 3OP0A 1AOUF 3HCKA 3CWGA 2XP1A 2MK2A 1A1AA 1BMBA 1P13A 4JEGA 1SHDA 3PS5A 2EOBA 4XZ1A 3OB2B 1O4JA 2KK6A 4LUEA 5EEQA 2L6KA 1OO3A 2ETZA 2OZOA 1RJAA 5EG3B 1O4CA 1QG1E 2C9WA 3PJPA 2EU0A 2YSXA 1MILA 5EELA 1JYUA 2YU7A 1A1CA 3GXWA 1X0NA 4F59A 2DLYA 1JWOA 1GHUA 3US4A 2MC1A 5GJHA 1G83A 5HKWA 1AB2A 1CWEA 1KA6A 1BHHB 2L3TA 3OB1B 2HMHA 1YVHA 1KC2A 3IMJA 1QADA 2RSYA 2AUGA 5EHPA 4NWFA 2IUHA 1R1QA 2ECDA 1D4WA 1F2FA 2H46E 1LUKA 1BFIA 2AOBA 2RORA 1O44A 1O4RA 2H5KA 3UYOA 3PQZA 2GE9A 1LUIA 4A4CA 1A07A 1AOTF 4K45A 5J3XA 2BBUA 4X6SA 3S8OA 1OPKA 3S8LA 3BUXB 1D1ZA 4WWQA 3VS5A 1Y57A 1O4NA 1YVLA 1O4GA 1FBZA 2K7AB 1IJRA
chains in the Genus database with same CATH superfamily
3N8MA 4FBNA 1FYRA 1A08A 3PSJA 1O4BA 1X27A 2KGYA 1NRVA 1LKKA 2C0OA 3CBLA 3CXLA 3QWYA 4F5AA 3VGOA 2EO6A 3TKZA 3VS4A 1SPSA 3TL0A 1A1BA 1HCTB 2EKXA 1TCEA 3VS2A 1H9OA 4JGHA 3HHMB 1I3ZA 2MRJA 1Z3KA 3CD3A 1R1SA 1NZLA 2HCKA 1A1EA 2EYZA 3N84A 1B47A 1O4QA 2L4KA 1CSYA 5AXIA 2CI9A 2OQ1A 3S8NA 4QSYA 1O48A 5DF6A 1AYAA 1GRIA 1BLJA 2EYVA 2DVJA 4GWFA 2B3OA 2Y1NA 1O47A 2Y3AB 1F1WA 3IN7A 1O4LA 3PLFB 2LNXA 3EAZA 2HUWA 1O4OA 2PLEA 1SPRA 2MRKA 1OO4A 4DGXA 1AYDA 2IUIA 4U17A 1A09A 3HIZB 3BUOB 4LUDA 2SHPA 5IBSA 1FHSA 3IMDA 4OHHA 2PNBA 1O4IA 1M27A 4A4BA 2LQWA 2JYQA 4H34A 2PLDA 1O43A 2CI8A 2GSBA 3C7IA 3GQIB 1MW4A 4EY0A 4H1OA 2VIFA 3VS7A 4DGPA 1LUMA 2LQNA 3VS1A 3ZNIA 1O4FA 2HDVA 3MAZA 1LUNA 3KFJA 2DCRA 1JU5A 3VS6A 5KAZA 1BG1A 3VRPA 3UF4A 3VRYA 1FMKA 4ROJA 1AYBA 1K9AA 4EIHA 2IZVA 5EHRA 4M4ZA 3WA4A 3VRNA 5CDWA 1QCFA 5BO4A 2LNWA 1OPLA 3VRZA 2AOAA 1BF5A 1BHFA 2DM0A 2DLZA 1BLKA 1AYCA 1WQUA 2CRHA 2CR4A 1FU5A 1RPYA 1HCSB 1O41A 1LKLA 1SHAA 4FL3A 2EYYA 4FL2A 1O49A 3VS3A 2ABLA 1O4KA 3K2MA 3PFVA 1O46A 4JE4A 1FU6A 5HKZA 4L1BB 3S9KA 4F5BA 1D4TA 3NHNA 3PSKA 2RVFA 5HKYA 5AULA 1IS0A 5D0JA 1O4EA 1CSZA 2KNOA 5I6VA 3BUMB 4D8KA 1O45A 4U1PA 2PNAA 3BUWB 4P9ZA 1JYQA 5DC4A 4XZ0A 2MQIA 2K79B 3VRQA 1O4DA 1PICA 4K2RA 4K11A 2EL8A 2EO3A 3VRRA 1CWDL 3EACA 3QWXX 1Y1UA 3BKBA 3M7FA 1BHHA 1O4MA 4E93A 1UURA 1LCKA 3K2TA 1A81A 2C0TA 2SRCA 1BFJA 1KSWA 2QMSA 1CJ1A 5IBMA 2IUGA 4E68A 2LCTA 1XA6A 1JYRA 1FBVA 1BKMA 4OHDA 4K44A 4TZIA 3VROA 2PTKA 1UUSA 5GJIA 2RMXA 3OVEA 1BM2A 1M61A 4OHLA 3MXYA 3OV1A 5DC0B 3IN8A 1BKLA 3N7YA 1AD5A 1NZVA 1SHBA 3T04A 1R1PA 2DX0A 1KA7A 1O4AA 1SKJA 2Y1MA 5DC9A 3MXCA 2C0IA 4P9VA 1RQQC 3BUNB 1O4PA 2CIAA 2FCIA 1TZEE 1O42A 4GL9E 2CBLA 3GXXA 1ZFPE 4NWGA 2H8HA 2HDXA 2CS0A 4GPLB 4OHIA 3VS0A 2FO0A 4OHEA 1X6CA 1O4HA 1LCJA 3OP0A 1AOUF 3HCKA 3CWGA 2XP1A 2MK2A 1A1AA 1BMBA 1P13A 4JEGA 1SHDA 3PS5A 2EOBA 4XZ1A 3OB2B 1O4JA 2KK6A 4LUEA 5EEQA 2L6KA 1OO3A 2LRAA 2ETZA 2OZOA 1RJAA 5EG3B 1O4CA 1QG1E 2C9WA 3PJPA 2EU0A 2YSXA 1MILA 5EELA 1JYUA 2YU7A 1A1CA 3GXWA 1X0NA 4F59A 2DLYA 1JWOA 1GHUA 3US4A 2MC1A 5GJHA 1G83A 5HKWA 1AB2A 1CWEA 1KA6A 1BHHB 2L3TA 3OB1B 2HMHA 1YVHA 1KC2A 3IMJA 1QADA 2RSYA 2AUGA 5EHPA 4NWFA 2IUHA 1R1QA 2ECDA 3LYVA 1D4WA 1F2FA 2H46E 1LUKA 1BFIA 2AOBA 2RORA 1O44A 1O4RA 2H5KA 3UYOA 3PQZA 2GE9A 1LUIA 4A4CA 1A07A 1AOTF 4K45A 5J3XA 2BBUA 4X6SA 3S8OA 1OPKA 3S8LA 3BUXB 1D1ZA 4WWQA 3VS5A 1Y57A 1O4NA 1YVLA 1O4GA 1FBZA 2K7AB 1IJRA
chains in the Genus database with same CATH topology
3N8MA 4FBNA 1FYRA 1A08A 3PSJA 1O4BA 1X27A 1NRVA 1LKKA 2C0OA 3CBLA 3CXLA 3QWYA 4F5AA 3VGOA 2EO6A 3TKZA 3VS4A 1SPSA 3TL0A 1A1BA 1HCTB 2EKXA 1TCEA 3VS2A 1H9OA 4JGHA 3HHMB 1I3ZA 2MRJA 1Z3KA 3CD3A 1R1SA 1NZLA 2HCKA 1A1EA 2EYZA 3N84A 1B47A 1O4QA 2L4KA 1CSYA 5AXIA 2CI9A 2OQ1A 3S8NA 4QSYA 1O48A 5DF6A 1AYAA 1GRIA 1BLJA 2EYVA 2DVJA 4GWFA 2B3OA 2Y1NA 1O47A 2Y3AB 1F1WA 3IN7A 1O4LA 3PLFB 2LNXA 3EAZA 2HUWA 1O4OA 2PLEA 1SPRA 2MRKA 1OO4A 4DGXA 1AYDA 2IUIA 4U17A 1A09A 3HIZB 3BUOB 4LUDA 2SHPA 5IBSA 1FHSA 3IMDA 4OHHA 2PNBA 1O4IA 1M27A 4A4BA 2LQWA 2JYQA 4H34A 2PLDA 1O43A 2CI8A 2GSBA 3C7IA 3GQIB 1MW4A 4EY0A 4H1OA 2VIFA 3VS7A 4DGPA 1LUMA 2LQNA 3VS1A 3ZNIA 1O4FA 2HDVA 3MAZA 1LUNA 3KFJA 2DCRA 1JU5A 3VS6A 5KAZA 1BG1A 3VRPA 3UF4A 3VRYA 1FMKA 4ROJA 1AYBA 1K9AA 4EIHA 2IZVA 5EHRA 4M4ZA 3WA4A 3VRNA 5CDWA 1QCFA 5BO4A 2LNWA 1OPLA 3VRZA 2AOAA 1BF5A 1BHFA 2DM0A 2DLZA 1BLKA 1AYCA 1WQUA 2CRHA 2CR4A 1FU5A 1RPYA 1HCSB 1O41A 1LKLA 1SHAA 4FL3A 2EYYA 4FL2A 1O49A 3VS3A 2ABLA 1O4KA 3K2MA 3PFVA 1O46A 4JE4A 1FU6A 5HKZA 4L1BB 3S9KA 4F5BA 1D4TA 3NHNA 3PSKA 2RVFA 5HKYA 5AULA 1IS0A 5D0JA 1O4EA 1CSZA 2KNOA 5I6VA 3BUMB 4D8KA 1O45A 4U1PA 2PNAA 3BUWB 4P9ZA 1JYQA 5DC4A 4XZ0A 2MQIA 2K79B 3VRQA 1O4DA 1PICA 4K2RA 4K11A 2EL8A 2EO3A 3VRRA 1CWDL 3EACA 3QWXX 1Y1UA 3BKBA 3M7FA 1BHHA 1O4MA 4E93A 1UURA 1LCKA 1A81A 2C0TA 2SRCA 1BFJA 1KSWA 2QMSA 1CJ1A 5IBMA 2IUGA 4E68A 2LCTA 1XA6A 1JYRA 1FBVA 1BKMA 4OHDA 4K44A 4TZIA 3VROA 2PTKA 1UUSA 5GJIA 2RMXA 3OVEA 1BM2A 1M61A 4OHLA 3MXYA 3OV1A 5DC0B 3IN8A 1BKLA 3N7YA 1AD5A 1NZVA 1SHBA 3T04A 1R1PA 2DX0A 1KA7A 1O4AA 1SKJA 2Y1MA 5DC9A 3MXCA 2C0IA 4P9VA 1RQQC 3BUNB 1O4PA 2CIAA 2FCIA 1TZEE 1O42A 4GL9E 2CBLA 3GXXA 1ZFPE 4NWGA 2H8HA 2HDXA 2CS0A 4GPLB 4OHIA 3VS0A 2FO0A 4OHEA 1X6CA 1O4HA 1LCJA 3OP0A 1AOUF 3HCKA 3CWGA 2XP1A 2MK2A 1A1AA 1BMBA 1P13A 4JEGA 1SHDA 3PS5A 2EOBA 4XZ1A 3OB2B 1O4JA 2KK6A 4LUEA 5EEQA 2L6KA 1OO3A 2ETZA 2OZOA 1RJAA 5EG3B 1O4CA 1QG1E 2C9WA 3PJPA 2EU0A 2YSXA 1MILA 5EELA 1JYUA 2YU7A 1A1CA 3GXWA 1X0NA 4F59A 2DLYA 1JWOA 1GHUA 3US4A 2MC1A 5GJHA 1G83A 5HKWA 1AB2A 1CWEA 1KA6A 1BHHB 2L3TA 3OB1B 2HMHA 1YVHA 1KC2A 3IMJA 1QADA 2RSYA 2AUGA 5EHPA 4NWFA 2IUHA 1R1QA 2ECDA 1D4WA 1F2FA 2H46E 1LUKA 1BFIA 2AOBA 2RORA 1O44A 1O4RA 2H5KA 3UYOA 3PQZA 2GE9A 1LUIA 4A4CA 1A07A 1AOTF 4K45A 5J3XA 2BBUA 4X6SA 3S8OA 1OPKA 3S8LA 3BUXB 1D1ZA 4WWQA 3VS5A 1Y57A 1O4NA 1YVLA 1O4GA 1FBZA 2K7AB 1IJRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N8M A;  4FBN A;  1FYR A;  1A08 A;  3PSJ A;  1O4B A;  1X27 A;  1NRV A;  1LKK A;  2C0O A;  3CBL A;  3CXL A;  3QWY A;  4F5A A;  3VGO A;  2EO6 A;  3TKZ A;  3VS4 A;  1SPS A;  3TL0 A;  1A1B A;  1HCT B;  2EKX A;  1TCE A;  3VS2 A;  1H9O A;  4JGH A;  3HHM B;  1I3Z A;  2MRJ A;  1Z3K A;  3CD3 A;  1R1S A;  1NZL A;  2HCK A;  1A1E A;  2EYZ A;  3N84 A;  1B47 A;  1O4Q A;  2L4K A;  1CSY A;  5AXI A;  2CI9 A;  2OQ1 A;  3S8N A;  4QSY A;  1O48 A;  5DF6 A;  1AYA A;  1GRI A;  1BLJ A;  2EYV A;  2DVJ A;  4GWF A;  2B3O A;  2Y1N A;  1O47 A;  2Y3A B;  1F1W A;  3IN7 A;  1O4L A;  3PLF B;  2LNX A;  3EAZ A;  2HUW A;  1O4O A;  2PLE A;  1SPR A;  2MRK A;  1OO4 A;  4DGX A;  1AYD A;  2IUI A;  4U17 A;  1A09 A;  3HIZ B;  3BUO B;  4LUD A;  2SHP A;  5IBS A;  1FHS A;  3IMD A;  4OHH A;  2PNB A;  1O4I A;  1M27 A;  4A4B A;  2LQW A;  2JYQ A;  4H34 A;  2PLD A;  1O43 A;  2CI8 A;  2GSB A;  3C7I A;  3GQI B;  1MW4 A;  4EY0 A;  4H1O A;  2VIF A;  3VS7 A;  4DGP A;  1LUM A;  2LQN A;  3VS1 A;  3ZNI A;  1O4F A;  2HDV A;  3MAZ A;  1LUN A;  3KFJ A;  2DCR A;  1JU5 A;  3VS6 A;  5KAZ A;  1BG1 A;  3VRP A;  3UF4 A;  3VRY A;  1FMK A;  4ROJ A;  1AYB A;  1K9A A;  4EIH A;  2IZV A;  5EHR A;  4M4Z A;  3WA4 A;  3VRN A;  5CDW A;  1QCF A;  5BO4 A;  2LNW A;  1OPL A;  3VRZ A;  2AOA A;  1BF5 A;  1BHF A;  2DM0 A;  2DLZ A;  1BLK A;  1AYC A;  1WQU A;  2CRH A;  2CR4 A;  1FU5 A;  1RPY A;  1HCS B;  1O41 A;  1LKL A;  1SHA A;  4FL3 A;  2EYY A;  4FL2 A;  1O49 A;  3VS3 A;  2ABL A;  1O4K A;  3K2M A;  3PFV A;  1O46 A;  4JE4 A;  1FU6 A;  5HKZ A;  4L1B B;  3S9K A;  4F5B A;  1D4T A;  3NHN A;  3PSK A;  2RVF A;  5HKY A;  5AUL A;  1IS0 A;  5D0J A;  1O4E A;  1CSZ A;  2KNO A;  5I6V A;  3BUM B;  4D8K A;  1O45 A;  4U1P A;  2PNA A;  3BUW B;  4P9Z A;  1JYQ A;  5DC4 A;  4XZ0 A;  2MQI A;  2K79 B;  3VRQ A;  1O4D A;  1PIC A;  4K2R A;  4K11 A;  2EL8 A;  2EO3 A;  3VRR A;  1CWD L;  3EAC A;  3QWX X;  1Y1U A;  3BKB A;  3M7F A;  1BHH A;  1O4M A;  4E93 A;  1UUR A;  1LCK A;  1A81 A;  2C0T A;  2SRC A;  1BFJ A;  1KSW A;  2QMS A;  1CJ1 A;  5IBM A;  2IUG A;  4E68 A;  2LCT A;  1XA6 A;  1JYR A;  1FBV A;  1BKM A;  4OHD A;  4K44 A;  4TZI A;  3VRO A;  2PTK A;  1UUS A;  5GJI A;  2RMX A;  3OVE A;  1BM2 A;  1M61 A;  4OHL A;  3MXY A;  3OV1 A;  5DC0 B;  3IN8 A;  1BKL A;  3N7Y A;  1AD5 A;  1NZV A;  1SHB A;  3T04 A;  1R1P A;  2DX0 A;  1KA7 A;  1O4A A;  1SKJ A;  2Y1M A;  5DC9 A;  3MXC A;  2C0I A;  4P9V A;  1RQQ C;  3BUN B;  1O4P A;  2CIA A;  2FCI A;  1TZE E;  1O42 A;  4GL9 E;  2CBL A;  3GXX A;  1ZFP E;  4NWG A;  2H8H A;  2HDX A;  2CS0 A;  4GPL B;  4OHI A;  3VS0 A;  2FO0 A;  4OHE A;  1X6C A;  1O4H A;  1LCJ A;  3OP0 A;  1AOU F;  3HCK A;  3CWG A;  2XP1 A;  2MK2 A;  1A1A A;  1BMB A;  1P13 A;  4JEG A;  1SHD A;  3PS5 A;  2EOB A;  4XZ1 A;  3OB2 B;  1O4J A;  2KK6 A;  4LUE A;  5EEQ A;  2L6K A;  1OO3 A;  2ETZ A;  2OZO A;  1RJA A;  5EG3 B;  1O4C A;  1QG1 E;  2C9W A;  3PJP A;  2EU0 A;  2YSX A;  1MIL A;  5EEL A;  1JYU A;  2YU7 A;  1A1C A;  3GXW A;  1X0N A;  4F59 A;  2DLY A;  1JWO A;  1GHU A;  3US4 A;  2MC1 A;  5GJH A;  1G83 A;  5HKW A;  1AB2 A;  1CWE A;  1KA6 A;  1BHH B;  2L3T A;  3OB1 B;  2HMH A;  1YVH A;  1KC2 A;  3IMJ A;  1QAD A;  2RSY A;  2AUG A;  5EHP A;  4NWF A;  2IUH A;  1R1Q A;  2ECD A;  1D4W A;  1F2F A;  2H46 E;  1LUK A;  1BFI A;  2AOB A;  2ROR A;  1O44 A;  1O4R A;  2H5K A;  3UYO A;  3PQZ A;  2GE9 A;  1LUI A;  4A4C A;  1A07 A;  1AOT F;  4K45 A;  5J3X A;  2BBU A;  4X6S A;  3S8O A;  1OPK A;  3S8L A;  3BUX B;  1D1Z A;  4WWQ A;  3VS5 A;  1Y57 A;  1O4N A;  1YVL A;  1O4G A;  1FBZ A;  2K7A B;  1IJR A; 
#chains in the Genus database with same CATH topology
 3N8M A;  4FBN A;  1FYR A;  1A08 A;  3PSJ A;  1O4B A;  1X27 A;  2KGY A;  1NRV A;  1LKK A;  2C0O A;  3CBL A;  3CXL A;  3QWY A;  4F5A A;  3VGO A;  2EO6 A;  3TKZ A;  3VS4 A;  1SPS A;  3TL0 A;  1A1B A;  1HCT B;  2EKX A;  1TCE A;  3VS2 A;  1H9O A;  4JGH A;  3HHM B;  1I3Z A;  2MRJ A;  1Z3K A;  3CD3 A;  1R1S A;  1NZL A;  2HCK A;  1A1E A;  2EYZ A;  3N84 A;  1B47 A;  1O4Q A;  2L4K A;  1CSY A;  5AXI A;  2CI9 A;  2OQ1 A;  3S8N A;  4QSY A;  1O48 A;  5DF6 A;  1AYA A;  1GRI A;  1BLJ A;  2EYV A;  2DVJ A;  4GWF A;  2B3O A;  2Y1N A;  1O47 A;  2Y3A B;  1F1W A;  3IN7 A;  1O4L A;  3PLF B;  2LNX A;  3EAZ A;  2HUW A;  1O4O A;  2PLE A;  1SPR A;  2MRK A;  1OO4 A;  4DGX A;  1AYD A;  2IUI A;  4U17 A;  1A09 A;  3HIZ B;  3BUO B;  4LUD A;  2SHP A;  5IBS A;  1FHS A;  3IMD A;  4OHH A;  2PNB A;  1O4I A;  1M27 A;  4A4B A;  2LQW A;  2JYQ A;  4H34 A;  2PLD A;  1O43 A;  2CI8 A;  2GSB A;  3C7I A;  3GQI B;  1MW4 A;  4EY0 A;  4H1O A;  2VIF A;  3VS7 A;  4DGP A;  1LUM A;  2LQN A;  3VS1 A;  3ZNI A;  1O4F A;  2HDV A;  3MAZ A;  1LUN A;  3KFJ A;  2DCR A;  1JU5 A;  3VS6 A;  5KAZ A;  1BG1 A;  3VRP A;  3UF4 A;  3VRY A;  1FMK A;  4ROJ A;  1AYB A;  1K9A A;  4EIH A;  2IZV A;  5EHR A;  4M4Z A;  3WA4 A;  3VRN A;  5CDW A;  1QCF A;  5BO4 A;  2LNW A;  1OPL A;  3VRZ A;  2AOA A;  1BF5 A;  1BHF A;  2DM0 A;  2DLZ A;  1BLK A;  1AYC A;  1WQU A;  2CRH A;  2CR4 A;  1FU5 A;  1RPY A;  1HCS B;  1O41 A;  1LKL A;  1SHA A;  4FL3 A;  2EYY A;  4FL2 A;  1O49 A;  3VS3 A;  2ABL A;  1O4K A;  3K2M A;  3PFV A;  1O46 A;  4JE4 A;  1FU6 A;  5HKZ A;  4L1B B;  3S9K A;  4F5B A;  1D4T A;  3NHN A;  3PSK A;  2RVF A;  5HKY A;  5AUL A;  1IS0 A;  5D0J A;  1O4E A;  1CSZ A;  2KNO A;  5I6V A;  3BUM B;  4D8K A;  1O45 A;  4U1P A;  2PNA A;  3BUW B;  4P9Z A;  1JYQ A;  5DC4 A;  4XZ0 A;  2MQI A;  2K79 B;  3VRQ A;  1O4D A;  1PIC A;  4K2R A;  4K11 A;  2EL8 A;  2EO3 A;  3VRR A;  1CWD L;  3EAC A;  3QWX X;  1Y1U A;  3BKB A;  3M7F A;  1BHH A;  1O4M A;  4E93 A;  1UUR A;  1LCK A;  3K2T A;  1A81 A;  2C0T A;  2SRC A;  1BFJ A;  1KSW A;  2QMS A;  1CJ1 A;  5IBM A;  2IUG A;  4E68 A;  2LCT A;  1XA6 A;  1JYR A;  1FBV A;  1BKM A;  4OHD A;  4K44 A;  4TZI A;  3VRO A;  2PTK A;  1UUS A;  5GJI A;  2RMX A;  3OVE A;  1BM2 A;  1M61 A;  4OHL A;  3MXY A;  3OV1 A;  5DC0 B;  3IN8 A;  1BKL A;  3N7Y A;  1AD5 A;  1NZV A;  1SHB A;  3T04 A;  1R1P A;  2DX0 A;  1KA7 A;  1O4A A;  1SKJ A;  2Y1M A;  5DC9 A;  3MXC A;  2C0I A;  4P9V A;  1RQQ C;  3BUN B;  1O4P A;  2CIA A;  2FCI A;  1TZE E;  1O42 A;  4GL9 E;  2CBL A;  3GXX A;  1ZFP E;  4NWG A;  2H8H A;  2HDX A;  2CS0 A;  4GPL B;  4OHI A;  3VS0 A;  2FO0 A;  4OHE A;  1X6C A;  1O4H A;  1LCJ A;  3OP0 A;  1AOU F;  3HCK A;  3CWG A;  2XP1 A;  2MK2 A;  1A1A A;  1BMB A;  1P13 A;  4JEG A;  1SHD A;  3PS5 A;  2EOB A;  4XZ1 A;  3OB2 B;  1O4J A;  2KK6 A;  4LUE A;  5EEQ A;  2L6K A;  1OO3 A;  2LRA A;  2ETZ A;  2OZO A;  1RJA A;  5EG3 B;  1O4C A;  1QG1 E;  2C9W A;  3PJP A;  2EU0 A;  2YSX A;  1MIL A;  5EEL A;  1JYU A;  2YU7 A;  1A1C A;  3GXW A;  1X0N A;  4F59 A;  2DLY A;  1JWO A;  1GHU A;  3US4 A;  2MC1 A;  5GJH A;  1G83 A;  5HKW A;  1AB2 A;  1CWE A;  1KA6 A;  1BHH B;  2L3T A;  3OB1 B;  2HMH A;  1YVH A;  1KC2 A;  3IMJ A;  1QAD A;  2RSY A;  2AUG A;  5EHP A;  4NWF A;  2IUH A;  1R1Q A;  2ECD A;  3LYV A;  1D4W A;  1F2F A;  2H46 E;  1LUK A;  1BFI A;  2AOB A;  2ROR A;  1O44 A;  1O4R A;  2H5K A;  3UYO A;  3PQZ A;  2GE9 A;  1LUI A;  4A4C A;  1A07 A;  1AOT F;  4K45 A;  5J3X A;  2BBU A;  4X6S A;  3S8O A;  1OPK A;  3S8L A;  3BUX B;  1D1Z A;  4WWQ A;  3VS5 A;  1Y57 A;  1O4N A;  1YVL A;  1O4G A;  1FBZ A;  2K7A B;  1IJR A; 
#chains in the Genus database with same CATH homology
 3N8M A;  4FBN A;  1FYR A;  1A08 A;  3PSJ A;  1O4B A;  1X27 A;  1NRV A;  1LKK A;  2C0O A;  3CBL A;  3CXL A;  3QWY A;  4F5A A;  3VGO A;  2EO6 A;  3TKZ A;  3VS4 A;  1SPS A;  3TL0 A;  1A1B A;  1HCT B;  2EKX A;  1TCE A;  3VS2 A;  1H9O A;  4JGH A;  3HHM B;  1I3Z A;  2MRJ A;  1Z3K A;  3CD3 A;  1R1S A;  1NZL A;  2HCK A;  1A1E A;  2EYZ A;  3N84 A;  1B47 A;  1O4Q A;  2L4K A;  1CSY A;  5AXI A;  2CI9 A;  2OQ1 A;  3S8N A;  4QSY A;  1O48 A;  5DF6 A;  1AYA A;  1GRI A;  1BLJ A;  2EYV A;  2DVJ A;  4GWF A;  2B3O A;  2Y1N A;  1O47 A;  2Y3A B;  1F1W A;  3IN7 A;  1O4L A;  3PLF B;  2LNX A;  3EAZ A;  2HUW A;  1O4O A;  2PLE A;  1SPR A;  2MRK A;  1OO4 A;  4DGX A;  1AYD A;  2IUI A;  4U17 A;  1A09 A;  3HIZ B;  3BUO B;  4LUD A;  2SHP A;  5IBS A;  1FHS A;  3IMD A;  4OHH A;  2PNB A;  1O4I A;  1M27 A;  4A4B A;  2LQW A;  2JYQ A;  4H34 A;  2PLD A;  1O43 A;  2CI8 A;  2GSB A;  3C7I A;  3GQI B;  1MW4 A;  4EY0 A;  4H1O A;  2VIF A;  3VS7 A;  4DGP A;  1LUM A;  2LQN A;  3VS1 A;  3ZNI A;  1O4F A;  2HDV A;  3MAZ A;  1LUN A;  3KFJ A;  2DCR A;  1JU5 A;  3VS6 A;  5KAZ A;  1BG1 A;  3VRP A;  3UF4 A;  3VRY A;  1FMK A;  4ROJ A;  1AYB A;  1K9A A;  4EIH A;  2IZV A;  5EHR A;  4M4Z A;  3WA4 A;  3VRN A;  5CDW A;  1QCF A;  5BO4 A;  2LNW A;  1OPL A;  3VRZ A;  2AOA A;  1BF5 A;  1BHF A;  2DM0 A;  2DLZ A;  1BLK A;  1AYC A;  1WQU A;  2CRH A;  2CR4 A;  1FU5 A;  1RPY A;  1HCS B;  1O41 A;  1LKL A;  1SHA A;  4FL3 A;  2EYY A;  4FL2 A;  1O49 A;  3VS3 A;  2ABL A;  1O4K A;  3K2M A;  3PFV A;  1O46 A;  4JE4 A;  1FU6 A;  5HKZ A;  4L1B B;  3S9K A;  4F5B A;  1D4T A;  3NHN A;  3PSK A;  2RVF A;  5HKY A;  5AUL A;  1IS0 A;  5D0J A;  1O4E A;  1CSZ A;  2KNO A;  5I6V A;  3BUM B;  4D8K A;  1O45 A;  4U1P A;  2PNA A;  3BUW B;  4P9Z A;  1JYQ A;  5DC4 A;  4XZ0 A;  2MQI A;  2K79 B;  3VRQ A;  1O4D A;  1PIC A;  4K2R A;  4K11 A;  2EL8 A;  2EO3 A;  3VRR A;  1CWD L;  3EAC A;  3QWX X;  1Y1U A;  3BKB A;  3M7F A;  1BHH A;  1O4M A;  4E93 A;  1UUR A;  1LCK A;  1A81 A;  2C0T A;  2SRC A;  1BFJ A;  1KSW A;  2QMS A;  1CJ1 A;  5IBM A;  2IUG A;  4E68 A;  2LCT A;  1XA6 A;  1JYR A;  1FBV A;  1BKM A;  4OHD A;  4K44 A;  4TZI A;  3VRO A;  2PTK A;  1UUS A;  5GJI A;  2RMX A;  3OVE A;  1BM2 A;  1M61 A;  4OHL A;  3MXY A;  3OV1 A;  5DC0 B;  3IN8 A;  1BKL A;  3N7Y A;  1AD5 A;  1NZV A;  1SHB A;  3T04 A;  1R1P A;  2DX0 A;  1KA7 A;  1O4A A;  1SKJ A;  2Y1M A;  5DC9 A;  3MXC A;  2C0I A;  4P9V A;  1RQQ C;  3BUN B;  1O4P A;  2CIA A;  2FCI A;  1TZE E;  1O42 A;  4GL9 E;  2CBL A;  3GXX A;  1ZFP E;  4NWG A;  2H8H A;  2HDX A;  2CS0 A;  4GPL B;  4OHI A;  3VS0 A;  2FO0 A;  4OHE A;  1X6C A;  1O4H A;  1LCJ A;  3OP0 A;  1AOU F;  3HCK A;  3CWG A;  2XP1 A;  2MK2 A;  1A1A A;  1BMB A;  1P13 A;  4JEG A;  1SHD A;  3PS5 A;  2EOB A;  4XZ1 A;  3OB2 B;  1O4J A;  2KK6 A;  4LUE A;  5EEQ A;  2L6K A;  1OO3 A;  2ETZ A;  2OZO A;  1RJA A;  5EG3 B;  1O4C A;  1QG1 E;  2C9W A;  3PJP A;  2EU0 A;  2YSX A;  1MIL A;  5EEL A;  1JYU A;  2YU7 A;  1A1C A;  3GXW A;  1X0N A;  4F59 A;  2DLY A;  1JWO A;  1GHU A;  3US4 A;  2MC1 A;  5GJH A;  1G83 A;  5HKW A;  1AB2 A;  1CWE A;  1KA6 A;  1BHH B;  2L3T A;  3OB1 B;  2HMH A;  1YVH A;  1KC2 A;  3IMJ A;  1QAD A;  2RSY A;  2AUG A;  5EHP A;  4NWF A;  2IUH A;  1R1Q A;  2ECD A;  1D4W A;  1F2F A;  2H46 E;  1LUK A;  1BFI A;  2AOB A;  2ROR A;  1O44 A;  1O4R A;  2H5K A;  3UYO A;  3PQZ A;  2GE9 A;  1LUI A;  4A4C A;  1A07 A;  1AOT F;  4K45 A;  5J3X A;  2BBU A;  4X6S A;  3S8O A;  1OPK A;  3S8L A;  3BUX B;  1D1Z A;  4WWQ A;  3VS5 A;  1Y57 A;  1O4N A;  1YVL A;  1O4G A;  1FBZ A;  2K7A B;  1IJR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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