5DF6A

Crystal structure of ptpn11 tandem sh2 domains in complex with a txnip peptide
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
217
structure length
212
Chain Sequence
RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESKSKVTHVMIRCQKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 56
structure length 212
sequence length 217
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2015-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5df6A01
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5df6A02
1F1WA 1O4HA 3VS7A 4U1PA 1O44A 2MQIA 3OVEA 1O46A 1AYDA 2SHPA 1O4QA 4JE4A 5GJHA 2JYQA 2RSYA 2AUGA 2EKXA 4K45A 4QSYA 1I3ZA 1KC2A 2QMSA 3MXCA 1FU5A 1KA7A 3VS0A 3GXWA 2AOBA 2K7AB 3HHMB 1JWOA 2CBLA 2RVFA 1A81A 3MAZA 1AYBA 2DX0A 3QWXX 1HCTB 1BHHB 3US4A 2Y3AB 5EEQA 3TL0A 2C9WA 3UYOA 1AYAA 2ABLA 3BUNB 2FO0A 1SHAA 1Y1UA 5EELA 1GRIA 2CS0A 4F5BA 1O4IA 4P9VA 1O4FA 3KFJA 1TZEE 3UF4A 1MW4A 1QCFA 3K2MA 1O4BA 3PS5A 1FYRA 2B3OA 2CRHA 1Z3KA 4EIHA 3S9KA 2RORA 4OHIA 3BKBA 1BG1A 1LUMA 4XZ0A 1D4TA 2LNXA 2YU7A 3IN8A 2BBUA 2MK2A 3BUWB 2YSXA 1IS0A 5AULA 3S8NA 2XP1A 2DLYA 4FL3A 3CWGA 1O49A 1O41A 1R1PA 4LUEA 1A1AA 2HMHA 3OP0A 4FBNA 5KAZA 4L1BB 3CBLA 1O47A 2OQ1A 1SKJA 2PNBA 1AB2A 3C7IA 4H1OA 3PQZA 2DM0A 1WQUA 1BMBA 2HCKA 1BM2A 4D8KA 1KA6A 2EYVA 4K2RA 3BUOB 3IN7A 3OB2B 5J3XA 3VS5A 3VS2A 1A1CA 3OV1A 1D1ZA 2EU0A 1H9OA 2IUGA 3T04A 5IBMA 4WWQA 3VRYA 4LUDA 5EHRA 1OO4A 1O4AA 3MXYA 3VROA 1FBVA 5CDWA 2KNOA 4GWFA 1X0NA 1OPLA 1NZVA 1RJAA 3N8MA 3ZNIA 3VRZA 1PICA 5DC0B 1HCSB 3BUXB 2KK6A 2C0IA 1O4NA 1O4MA 2H8HA 2IUHA 3S8OA 2ECDA 3VRNA 4F59A 2OZOA 2SRCA 1CSZA 1K9AA 1JYQA 3PSKA 2EYYA 4E93A 3PLFB 2K79B 4DGXA 1BKLA 2L3TA 4EY0A 2PLDA 1YVHA 1O4RA 3PFVA 2PTKA 1RPYA 2MC1A 2RMXA 1SHDA 1G83A 5HKYA 1R1QA 1CWEA 3CD3A 2EOBA 1A08A 1CSYA 1SPRA 1LUIA 3N84A 3IMJA 2PLEA 2Y1MA 1GHUA 2CIAA 2CI9A 4NWGA 3VS3A 4JEGA 4ROJA 1BLJA 1A1EA 1KSWA 1BF5A 4K44A 1SHBA 2L4KA 1M61A 1NZLA 5DC4A 1NRVA 4OHLA 4F5AA 2VIFA 3PJPA 4OHDA 3HCKA 3NHNA 1BKMA 4FL2A 2LQWA 2EO3A 2LQNA 1JU5A 5DF6A 4M4ZA 1BFIA 3M7FA 5D0JA 2CI8A 1FBZA 2HUWA 1LKLA 1CJ1A 5HKWA 3OB1B 1FHSA 1Y57A 1LUNA 2IUIA 4H34A 5HKZA 2H5KA 1BHFA 1LUKA 4E68A 4TZIA 1O4KA 2MRJA 2LNWA 5AXIA 3BUMB 1UUSA 3VRRA 3QWYA 2H46E 4DGPA 2DCRA 2DLZA 1AYCA 3GXXA 3EACA 1O4EA 3VS1A 1AD5A 4NWFA 1LKKA 1B47A 1X27A 1O45A 1TCEA 3VS4A 3EAZA 1P13A 1CWDL 1O4JA 1RQQC 2ETZA 1FU6A 1O43A 1QG1E 1XA6A 2GSBA 3HIZB 1JYRA 2EO6A 3PSJA 1F2FA 1MILA 5IBSA 3S8LA 1ZFPE 2L6KA 4P9ZA 5DC9A 1AOUF 1UURA 1O4LA 3TKZA 1BLKA 4OHEA 2Y1NA 4X6SA 3VGOA 4K11A 2GE9A 5EHPA 1OO3A 1FMKA 2HDXA 1A09A 1YVLA 5BO4A 1LCKA 2AOAA 4OHHA 1O42A 1SPSA 1O4DA 2FCIA 3WA4A 2EYZA 4U17A 5EG3B 1X6CA 1IJRA 1A1BA 2CR4A 2PNAA 4A4CA 2HDVA 1O4CA 1O48A 2EL8A 2C0OA 2MRKA 4JGHA 2LCTA 1OPKA 1JYUA 1A07A 1D4WA 4GL9E 2IZVA 3VS6A 3VRPA 1O4PA 3IMDA 1O4OA 1R1SA 3CXLA 1QADA 2C0TA 4A4BA 1M27A 3N7YA 5GJIA 1BFJA 1O4GA 1LCJA 4XZ1A 3VRQA 2DVJA 4GPLB 5I6VA 1BHHA 1AOTF 3GQIB
chains in the Genus database with same CATH superfamily
1F1WA 1O4HA 3VS7A 4U1PA 1O44A 2MQIA 3OVEA 1O46A 1AYDA 2SHPA 1O4QA 4JE4A 5GJHA 2JYQA 2RSYA 2AUGA 2EKXA 4K45A 4QSYA 1I3ZA 1KC2A 2QMSA 3MXCA 1FU5A 1KA7A 3VS0A 3GXWA 2AOBA 2K7AB 3HHMB 1JWOA 2CBLA 2RVFA 1A81A 3MAZA 1AYBA 2DX0A 3QWXX 1HCTB 1BHHB 3US4A 2Y3AB 5EEQA 3TL0A 2C9WA 3UYOA 1AYAA 2ABLA 3BUNB 2FO0A 1SHAA 1Y1UA 5EELA 1GRIA 2CS0A 4F5BA 1O4IA 4P9VA 1O4FA 3KFJA 1TZEE 3UF4A 1MW4A 1QCFA 3K2MA 1O4BA 3PS5A 1FYRA 2B3OA 2CRHA 1Z3KA 4EIHA 3S9KA 2RORA 4OHIA 3BKBA 1BG1A 1LUMA 4XZ0A 1D4TA 2LNXA 2YU7A 3IN8A 2BBUA 2MK2A 3BUWB 2YSXA 1IS0A 5AULA 3S8NA 2XP1A 2DLYA 4FL3A 3CWGA 1O49A 1O41A 1R1PA 4LUEA 1A1AA 2HMHA 3OP0A 4FBNA 5KAZA 4L1BB 3CBLA 1O47A 2OQ1A 1SKJA 2PNBA 3K2TA 1AB2A 3C7IA 4H1OA 3PQZA 2DM0A 1WQUA 1BMBA 2HCKA 1BM2A 4D8KA 1KA6A 2EYVA 4K2RA 3BUOB 3IN7A 3OB2B 5J3XA 3VS5A 3VS2A 1A1CA 3OV1A 1D1ZA 2EU0A 1H9OA 2IUGA 3T04A 5IBMA 4WWQA 3VRYA 4LUDA 5EHRA 1OO4A 1O4AA 3MXYA 3VROA 1FBVA 5CDWA 2KNOA 4GWFA 1X0NA 1OPLA 1NZVA 1RJAA 3N8MA 3ZNIA 3VRZA 1PICA 5DC0B 1HCSB 3BUXB 2KK6A 2C0IA 1O4NA 1O4MA 2H8HA 2IUHA 3S8OA 2ECDA 3VRNA 4F59A 2OZOA 2SRCA 1CSZA 1K9AA 1JYQA 3PSKA 2EYYA 4E93A 3PLFB 2K79B 4DGXA 1BKLA 2L3TA 4EY0A 2PLDA 1YVHA 1O4RA 3PFVA 2PTKA 1RPYA 2MC1A 2RMXA 1SHDA 1G83A 5HKYA 1R1QA 1CWEA 3CD3A 2EOBA 1A08A 1CSYA 1SPRA 1LUIA 3N84A 3IMJA 2PLEA 2Y1MA 1GHUA 2CIAA 2CI9A 4NWGA 3VS3A 4JEGA 4ROJA 1BLJA 1A1EA 1KSWA 1BF5A 4K44A 1SHBA 2L4KA 1M61A 1NZLA 5DC4A 1NRVA 4OHLA 4F5AA 2VIFA 3PJPA 4OHDA 3HCKA 3NHNA 1BKMA 4FL2A 2LQWA 2EO3A 2LQNA 1JU5A 5DF6A 4M4ZA 1BFIA 3M7FA 5D0JA 2CI8A 1FBZA 2HUWA 1LKLA 1CJ1A 5HKWA 3OB1B 1FHSA 1Y57A 1LUNA 2IUIA 4H34A 5HKZA 2H5KA 1BHFA 1LUKA 4E68A 4TZIA 1O4KA 2MRJA 2LNWA 5AXIA 3BUMB 1UUSA 3VRRA 3QWYA 2H46E 4DGPA 2DCRA 2DLZA 1AYCA 3GXXA 3EACA 1O4EA 3VS1A 1AD5A 4NWFA 1LKKA 1B47A 1X27A 1O45A 1TCEA 3VS4A 3EAZA 1P13A 1CWDL 1O4JA 1RQQC 2ETZA 1FU6A 1O43A 1QG1E 1XA6A 2GSBA 3HIZB 1JYRA 2EO6A 3PSJA 1F2FA 1MILA 5IBSA 3S8LA 1ZFPE 2L6KA 4P9ZA 5DC9A 1AOUF 1UURA 1O4LA 3TKZA 1BLKA 4OHEA 2Y1NA 4X6SA 3VGOA 4K11A 2GE9A 5EHPA 1OO3A 1FMKA 2HDXA 1A09A 1YVLA 5BO4A 1LCKA 2AOAA 4OHHA 1O42A 1SPSA 1O4DA 2FCIA 3WA4A 2EYZA 4U17A 5EG3B 1X6CA 1IJRA 1A1BA 2CR4A 2PNAA 4A4CA 2HDVA 1O4CA 1O48A 2EL8A 2C0OA 3LYVA 2LRAA 2MRKA 4JGHA 2LCTA 1OPKA 1JYUA 1A07A 1D4WA 4GL9E 2IZVA 3VS6A 3VRPA 1O4PA 3IMDA 1O4OA 1R1SA 3CXLA 1QADA 2C0TA 4A4BA 1M27A 3N7YA 5GJIA 1BFJA 2KGYA 1O4GA 1LCJA 4XZ1A 3VRQA 2DVJA 4GPLB 5I6VA 1BHHA 1AOTF 3GQIB
chains in the Genus database with same CATH topology
1F1WA 1O4HA 3VS7A 4U1PA 1O44A 2MQIA 3OVEA 1O46A 1AYDA 2SHPA 1O4QA 4JE4A 5GJHA 2JYQA 2RSYA 2AUGA 2EKXA 4K45A 4QSYA 1I3ZA 1KC2A 2QMSA 3MXCA 1FU5A 1KA7A 3VS0A 3GXWA 2AOBA 2K7AB 3HHMB 1JWOA 2CBLA 2RVFA 1A81A 3MAZA 1AYBA 2DX0A 3QWXX 1HCTB 1BHHB 3US4A 2Y3AB 5EEQA 3TL0A 2C9WA 3UYOA 1AYAA 2ABLA 3BUNB 2FO0A 1SHAA 1Y1UA 5EELA 1GRIA 2CS0A 4F5BA 1O4IA 4P9VA 1O4FA 3KFJA 1TZEE 3UF4A 1MW4A 1QCFA 3K2MA 1O4BA 3PS5A 1FYRA 2B3OA 2CRHA 1Z3KA 4EIHA 3S9KA 2RORA 4OHIA 3BKBA 1BG1A 1LUMA 4XZ0A 1D4TA 2LNXA 2YU7A 3IN8A 2BBUA 2MK2A 3BUWB 2YSXA 1IS0A 5AULA 3S8NA 2XP1A 2DLYA 4FL3A 3CWGA 1O49A 1O41A 1R1PA 4LUEA 1A1AA 2HMHA 3OP0A 4FBNA 5KAZA 4L1BB 3CBLA 1O47A 2OQ1A 1SKJA 2PNBA 1AB2A 3C7IA 4H1OA 3PQZA 2DM0A 1WQUA 1BMBA 2HCKA 1BM2A 4D8KA 1KA6A 2EYVA 4K2RA 3BUOB 3IN7A 3OB2B 5J3XA 3VS5A 3VS2A 1A1CA 3OV1A 1D1ZA 2EU0A 1H9OA 2IUGA 3T04A 5IBMA 4WWQA 3VRYA 4LUDA 5EHRA 1OO4A 1O4AA 3MXYA 3VROA 1FBVA 5CDWA 2KNOA 4GWFA 1X0NA 1OPLA 1NZVA 1RJAA 3N8MA 3ZNIA 3VRZA 1PICA 5DC0B 1HCSB 3BUXB 2KK6A 2C0IA 1O4NA 1O4MA 2H8HA 2IUHA 3S8OA 2ECDA 3VRNA 4F59A 2OZOA 2SRCA 1CSZA 1K9AA 1JYQA 3PSKA 2EYYA 4E93A 3PLFB 2K79B 4DGXA 1BKLA 2L3TA 4EY0A 2PLDA 1YVHA 1O4RA 3PFVA 2PTKA 1RPYA 2MC1A 2RMXA 1SHDA 1G83A 5HKYA 1R1QA 1CWEA 3CD3A 2EOBA 1A08A 1CSYA 1SPRA 1LUIA 3N84A 3IMJA 2PLEA 2Y1MA 1GHUA 2CIAA 2CI9A 4NWGA 3VS3A 4JEGA 4ROJA 1BLJA 1A1EA 1KSWA 1BF5A 4K44A 1SHBA 2L4KA 1M61A 1NZLA 5DC4A 1NRVA 4OHLA 4F5AA 2VIFA 3PJPA 4OHDA 3HCKA 3NHNA 1BKMA 4FL2A 2LQWA 2EO3A 2LQNA 1JU5A 5DF6A 4M4ZA 1BFIA 3M7FA 5D0JA 2CI8A 1FBZA 2HUWA 1LKLA 1CJ1A 5HKWA 3OB1B 1FHSA 1Y57A 1LUNA 2IUIA 4H34A 5HKZA 2H5KA 1BHFA 1LUKA 4E68A 4TZIA 1O4KA 2MRJA 2LNWA 5AXIA 3BUMB 1UUSA 3VRRA 3QWYA 2H46E 4DGPA 2DCRA 2DLZA 1AYCA 3GXXA 3EACA 1O4EA 3VS1A 1AD5A 4NWFA 1LKKA 1B47A 1X27A 1O45A 1TCEA 3VS4A 3EAZA 1P13A 1CWDL 1O4JA 1RQQC 2ETZA 1FU6A 1O43A 1QG1E 1XA6A 2GSBA 3HIZB 1JYRA 2EO6A 3PSJA 1F2FA 1MILA 5IBSA 3S8LA 1ZFPE 2L6KA 4P9ZA 5DC9A 1AOUF 1UURA 1O4LA 3TKZA 1BLKA 4OHEA 2Y1NA 4X6SA 3VGOA 4K11A 2GE9A 5EHPA 1OO3A 1FMKA 2HDXA 1A09A 1YVLA 5BO4A 1LCKA 2AOAA 4OHHA 1O42A 1SPSA 1O4DA 2FCIA 3WA4A 2EYZA 4U17A 5EG3B 1X6CA 1IJRA 1A1BA 2CR4A 2PNAA 4A4CA 2HDVA 1O4CA 1O48A 2EL8A 2C0OA 2MRKA 4JGHA 2LCTA 1OPKA 1JYUA 1A07A 1D4WA 4GL9E 2IZVA 3VS6A 3VRPA 1O4PA 3IMDA 1O4OA 1R1SA 3CXLA 1QADA 2C0TA 4A4BA 1M27A 3N7YA 5GJIA 1BFJA 1O4GA 1LCJA 4XZ1A 3VRQA 2DVJA 4GPLB 5I6VA 1BHHA 1AOTF 3GQIB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F1W A;  1O4H A;  3VS7 A;  4U1P A;  1O44 A;  2MQI A;  3OVE A;  1O46 A;  1AYD A;  2SHP A;  1O4Q A;  4JE4 A;  5GJH A;  2JYQ A;  2RSY A;  2AUG A;  2EKX A;  4K45 A;  4QSY A;  1I3Z A;  1KC2 A;  2QMS A;  3MXC A;  1FU5 A;  1KA7 A;  3VS0 A;  3GXW A;  2AOB A;  2K7A B;  3HHM B;  1JWO A;  2CBL A;  2RVF A;  1A81 A;  3MAZ A;  1AYB A;  2DX0 A;  3QWX X;  1HCT B;  1BHH B;  3US4 A;  2Y3A B;  5EEQ A;  3TL0 A;  2C9W A;  3UYO A;  1AYA A;  2ABL A;  3BUN B;  2FO0 A;  1SHA A;  1Y1U A;  5EEL A;  1GRI A;  2CS0 A;  4F5B A;  1O4I A;  4P9V A;  1O4F A;  3KFJ A;  1TZE E;  3UF4 A;  1MW4 A;  1QCF A;  3K2M A;  1O4B A;  3PS5 A;  1FYR A;  2B3O A;  2CRH A;  1Z3K A;  4EIH A;  3S9K A;  2ROR A;  4OHI A;  3BKB A;  1BG1 A;  1LUM A;  4XZ0 A;  1D4T A;  2LNX A;  2YU7 A;  3IN8 A;  2BBU A;  2MK2 A;  3BUW B;  2YSX A;  1IS0 A;  5AUL A;  3S8N A;  2XP1 A;  2DLY A;  4FL3 A;  3CWG A;  1O49 A;  1O41 A;  1R1P A;  4LUE A;  1A1A A;  2HMH A;  3OP0 A;  4FBN A;  5KAZ A;  4L1B B;  3CBL A;  1O47 A;  2OQ1 A;  1SKJ A;  2PNB A;  1AB2 A;  3C7I A;  4H1O A;  3PQZ A;  2DM0 A;  1WQU A;  1BMB A;  2HCK A;  1BM2 A;  4D8K A;  1KA6 A;  2EYV A;  4K2R A;  3BUO B;  3IN7 A;  3OB2 B;  5J3X A;  3VS5 A;  3VS2 A;  1A1C A;  3OV1 A;  1D1Z A;  2EU0 A;  1H9O A;  2IUG A;  3T04 A;  5IBM A;  4WWQ A;  3VRY A;  4LUD A;  5EHR A;  1OO4 A;  1O4A A;  3MXY A;  3VRO A;  1FBV A;  5CDW A;  2KNO A;  4GWF A;  1X0N A;  1OPL A;  1NZV A;  1RJA A;  3N8M A;  3ZNI A;  3VRZ A;  1PIC A;  5DC0 B;  1HCS B;  3BUX B;  2KK6 A;  2C0I A;  1O4N A;  1O4M A;  2H8H A;  2IUH A;  3S8O A;  2ECD A;  3VRN A;  4F59 A;  2OZO A;  2SRC A;  1CSZ A;  1K9A A;  1JYQ A;  3PSK A;  2EYY A;  4E93 A;  3PLF B;  2K79 B;  4DGX A;  1BKL A;  2L3T A;  4EY0 A;  2PLD A;  1YVH A;  1O4R A;  3PFV A;  2PTK A;  1RPY A;  2MC1 A;  2RMX A;  1SHD A;  1G83 A;  5HKY A;  1R1Q A;  1CWE A;  3CD3 A;  2EOB A;  1A08 A;  1CSY A;  1SPR A;  1LUI A;  3N84 A;  3IMJ A;  2PLE A;  2Y1M A;  1GHU A;  2CIA A;  2CI9 A;  4NWG A;  3VS3 A;  4JEG A;  4ROJ A;  1BLJ A;  1A1E A;  1KSW A;  1BF5 A;  4K44 A;  1SHB A;  2L4K A;  1M61 A;  1NZL A;  5DC4 A;  1NRV A;  4OHL A;  4F5A A;  2VIF A;  3PJP A;  4OHD A;  3HCK A;  3NHN A;  1BKM A;  4FL2 A;  2LQW A;  2EO3 A;  2LQN A;  1JU5 A;  5DF6 A;  4M4Z A;  1BFI A;  3M7F A;  5D0J A;  2CI8 A;  1FBZ A;  2HUW A;  1LKL A;  1CJ1 A;  5HKW A;  3OB1 B;  1FHS A;  1Y57 A;  1LUN A;  2IUI A;  4H34 A;  5HKZ A;  2H5K A;  1BHF A;  1LUK A;  4E68 A;  4TZI A;  1O4K A;  2MRJ A;  2LNW A;  5AXI A;  3BUM B;  1UUS A;  3VRR A;  3QWY A;  2H46 E;  4DGP A;  2DCR A;  2DLZ A;  1AYC A;  3GXX A;  3EAC A;  1O4E A;  3VS1 A;  1AD5 A;  4NWF A;  1LKK A;  1B47 A;  1X27 A;  1O45 A;  1TCE A;  3VS4 A;  3EAZ A;  1P13 A;  1CWD L;  1O4J A;  1RQQ C;  2ETZ A;  1FU6 A;  1O43 A;  1QG1 E;  1XA6 A;  2GSB A;  3HIZ B;  1JYR A;  2EO6 A;  3PSJ A;  1F2F A;  1MIL A;  5IBS A;  3S8L A;  1ZFP E;  2L6K A;  4P9Z A;  5DC9 A;  1AOU F;  1UUR A;  1O4L A;  3TKZ A;  1BLK A;  4OHE A;  2Y1N A;  4X6S A;  3VGO A;  4K11 A;  2GE9 A;  5EHP A;  1OO3 A;  1FMK A;  2HDX A;  1A09 A;  1YVL A;  5BO4 A;  1LCK A;  2AOA A;  4OHH A;  1O42 A;  1SPS A;  1O4D A;  2FCI A;  3WA4 A;  2EYZ A;  4U17 A;  5EG3 B;  1X6C A;  1IJR A;  1A1B A;  2CR4 A;  2PNA A;  4A4C A;  2HDV A;  1O4C A;  1O48 A;  2EL8 A;  2C0O A;  2MRK A;  4JGH A;  2LCT A;  1OPK A;  1JYU A;  1A07 A;  1D4W A;  4GL9 E;  2IZV A;  3VS6 A;  3VRP A;  1O4P A;  3IMD A;  1O4O A;  1R1S A;  3CXL A;  1QAD A;  2C0T A;  4A4B A;  1M27 A;  3N7Y A;  5GJI A;  1BFJ A;  1O4G A;  1LCJ A;  4XZ1 A;  3VRQ A;  2DVJ A;  4GPL B;  5I6V A;  1BHH A;  1AOT F;  3GQI B; 
#chains in the Genus database with same CATH topology
 1F1W A;  1O4H A;  3VS7 A;  4U1P A;  1O44 A;  2MQI A;  3OVE A;  1O46 A;  1AYD A;  2SHP A;  1O4Q A;  4JE4 A;  5GJH A;  2JYQ A;  2RSY A;  2AUG A;  2EKX A;  4K45 A;  4QSY A;  1I3Z A;  1KC2 A;  2QMS A;  3MXC A;  1FU5 A;  1KA7 A;  3VS0 A;  3GXW A;  2AOB A;  2K7A B;  3HHM B;  1JWO A;  2CBL A;  2RVF A;  1A81 A;  3MAZ A;  1AYB A;  2DX0 A;  3QWX X;  1HCT B;  1BHH B;  3US4 A;  2Y3A B;  5EEQ A;  3TL0 A;  2C9W A;  3UYO A;  1AYA A;  2ABL A;  3BUN B;  2FO0 A;  1SHA A;  1Y1U A;  5EEL A;  1GRI A;  2CS0 A;  4F5B A;  1O4I A;  4P9V A;  1O4F A;  3KFJ A;  1TZE E;  3UF4 A;  1MW4 A;  1QCF A;  3K2M A;  1O4B A;  3PS5 A;  1FYR A;  2B3O A;  2CRH A;  1Z3K A;  4EIH A;  3S9K A;  2ROR A;  4OHI A;  3BKB A;  1BG1 A;  1LUM A;  4XZ0 A;  1D4T A;  2LNX A;  2YU7 A;  3IN8 A;  2BBU A;  2MK2 A;  3BUW B;  2YSX A;  1IS0 A;  5AUL A;  3S8N A;  2XP1 A;  2DLY A;  4FL3 A;  3CWG A;  1O49 A;  1O41 A;  1R1P A;  4LUE A;  1A1A A;  2HMH A;  3OP0 A;  4FBN A;  5KAZ A;  4L1B B;  3CBL A;  1O47 A;  2OQ1 A;  1SKJ A;  2PNB A;  3K2T A;  1AB2 A;  3C7I A;  4H1O A;  3PQZ A;  2DM0 A;  1WQU A;  1BMB A;  2HCK A;  1BM2 A;  4D8K A;  1KA6 A;  2EYV A;  4K2R A;  3BUO B;  3IN7 A;  3OB2 B;  5J3X A;  3VS5 A;  3VS2 A;  1A1C A;  3OV1 A;  1D1Z A;  2EU0 A;  1H9O A;  2IUG A;  3T04 A;  5IBM A;  4WWQ A;  3VRY A;  4LUD A;  5EHR A;  1OO4 A;  1O4A A;  3MXY A;  3VRO A;  1FBV A;  5CDW A;  2KNO A;  4GWF A;  1X0N A;  1OPL A;  1NZV A;  1RJA A;  3N8M A;  3ZNI A;  3VRZ A;  1PIC A;  5DC0 B;  1HCS B;  3BUX B;  2KK6 A;  2C0I A;  1O4N A;  1O4M A;  2H8H A;  2IUH A;  3S8O A;  2ECD A;  3VRN A;  4F59 A;  2OZO A;  2SRC A;  1CSZ A;  1K9A A;  1JYQ A;  3PSK A;  2EYY A;  4E93 A;  3PLF B;  2K79 B;  4DGX A;  1BKL A;  2L3T A;  4EY0 A;  2PLD A;  1YVH A;  1O4R A;  3PFV A;  2PTK A;  1RPY A;  2MC1 A;  2RMX A;  1SHD A;  1G83 A;  5HKY A;  1R1Q A;  1CWE A;  3CD3 A;  2EOB A;  1A08 A;  1CSY A;  1SPR A;  1LUI A;  3N84 A;  3IMJ A;  2PLE A;  2Y1M A;  1GHU A;  2CIA A;  2CI9 A;  4NWG A;  3VS3 A;  4JEG A;  4ROJ A;  1BLJ A;  1A1E A;  1KSW A;  1BF5 A;  4K44 A;  1SHB A;  2L4K A;  1M61 A;  1NZL A;  5DC4 A;  1NRV A;  4OHL A;  4F5A A;  2VIF A;  3PJP A;  4OHD A;  3HCK A;  3NHN A;  1BKM A;  4FL2 A;  2LQW A;  2EO3 A;  2LQN A;  1JU5 A;  5DF6 A;  4M4Z A;  1BFI A;  3M7F A;  5D0J A;  2CI8 A;  1FBZ A;  2HUW A;  1LKL A;  1CJ1 A;  5HKW A;  3OB1 B;  1FHS A;  1Y57 A;  1LUN A;  2IUI A;  4H34 A;  5HKZ A;  2H5K A;  1BHF A;  1LUK A;  4E68 A;  4TZI A;  1O4K A;  2MRJ A;  2LNW A;  5AXI A;  3BUM B;  1UUS A;  3VRR A;  3QWY A;  2H46 E;  4DGP A;  2DCR A;  2DLZ A;  1AYC A;  3GXX A;  3EAC A;  1O4E A;  3VS1 A;  1AD5 A;  4NWF A;  1LKK A;  1B47 A;  1X27 A;  1O45 A;  1TCE A;  3VS4 A;  3EAZ A;  1P13 A;  1CWD L;  1O4J A;  1RQQ C;  2ETZ A;  1FU6 A;  1O43 A;  1QG1 E;  1XA6 A;  2GSB A;  3HIZ B;  1JYR A;  2EO6 A;  3PSJ A;  1F2F A;  1MIL A;  5IBS A;  3S8L A;  1ZFP E;  2L6K A;  4P9Z A;  5DC9 A;  1AOU F;  1UUR A;  1O4L A;  3TKZ A;  1BLK A;  4OHE A;  2Y1N A;  4X6S A;  3VGO A;  4K11 A;  2GE9 A;  5EHP A;  1OO3 A;  1FMK A;  2HDX A;  1A09 A;  1YVL A;  5BO4 A;  1LCK A;  2AOA A;  4OHH A;  1O42 A;  1SPS A;  1O4D A;  2FCI A;  3WA4 A;  2EYZ A;  4U17 A;  5EG3 B;  1X6C A;  1IJR A;  1A1B A;  2CR4 A;  2PNA A;  4A4C A;  2HDV A;  1O4C A;  1O48 A;  2EL8 A;  2C0O A;  3LYV A;  2LRA A;  2MRK A;  4JGH A;  2LCT A;  1OPK A;  1JYU A;  1A07 A;  1D4W A;  4GL9 E;  2IZV A;  3VS6 A;  3VRP A;  1O4P A;  3IMD A;  1O4O A;  1R1S A;  3CXL A;  1QAD A;  2C0T A;  4A4B A;  1M27 A;  3N7Y A;  5GJI A;  1BFJ A;  2KGY A;  1O4G A;  1LCJ A;  4XZ1 A;  3VRQ A;  2DVJ A;  4GPL B;  5I6V A;  1BHH A;  1AOT F;  3GQI B; 
#chains in the Genus database with same CATH homology
 1F1W A;  1O4H A;  3VS7 A;  4U1P A;  1O44 A;  2MQI A;  3OVE A;  1O46 A;  1AYD A;  2SHP A;  1O4Q A;  4JE4 A;  5GJH A;  2JYQ A;  2RSY A;  2AUG A;  2EKX A;  4K45 A;  4QSY A;  1I3Z A;  1KC2 A;  2QMS A;  3MXC A;  1FU5 A;  1KA7 A;  3VS0 A;  3GXW A;  2AOB A;  2K7A B;  3HHM B;  1JWO A;  2CBL A;  2RVF A;  1A81 A;  3MAZ A;  1AYB A;  2DX0 A;  3QWX X;  1HCT B;  1BHH B;  3US4 A;  2Y3A B;  5EEQ A;  3TL0 A;  2C9W A;  3UYO A;  1AYA A;  2ABL A;  3BUN B;  2FO0 A;  1SHA A;  1Y1U A;  5EEL A;  1GRI A;  2CS0 A;  4F5B A;  1O4I A;  4P9V A;  1O4F A;  3KFJ A;  1TZE E;  3UF4 A;  1MW4 A;  1QCF A;  3K2M A;  1O4B A;  3PS5 A;  1FYR A;  2B3O A;  2CRH A;  1Z3K A;  4EIH A;  3S9K A;  2ROR A;  4OHI A;  3BKB A;  1BG1 A;  1LUM A;  4XZ0 A;  1D4T A;  2LNX A;  2YU7 A;  3IN8 A;  2BBU A;  2MK2 A;  3BUW B;  2YSX A;  1IS0 A;  5AUL A;  3S8N A;  2XP1 A;  2DLY A;  4FL3 A;  3CWG A;  1O49 A;  1O41 A;  1R1P A;  4LUE A;  1A1A A;  2HMH A;  3OP0 A;  4FBN A;  5KAZ A;  4L1B B;  3CBL A;  1O47 A;  2OQ1 A;  1SKJ A;  2PNB A;  1AB2 A;  3C7I A;  4H1O A;  3PQZ A;  2DM0 A;  1WQU A;  1BMB A;  2HCK A;  1BM2 A;  4D8K A;  1KA6 A;  2EYV A;  4K2R A;  3BUO B;  3IN7 A;  3OB2 B;  5J3X A;  3VS5 A;  3VS2 A;  1A1C A;  3OV1 A;  1D1Z A;  2EU0 A;  1H9O A;  2IUG A;  3T04 A;  5IBM A;  4WWQ A;  3VRY A;  4LUD A;  5EHR A;  1OO4 A;  1O4A A;  3MXY A;  3VRO A;  1FBV A;  5CDW A;  2KNO A;  4GWF A;  1X0N A;  1OPL A;  1NZV A;  1RJA A;  3N8M A;  3ZNI A;  3VRZ A;  1PIC A;  5DC0 B;  1HCS B;  3BUX B;  2KK6 A;  2C0I A;  1O4N A;  1O4M A;  2H8H A;  2IUH A;  3S8O A;  2ECD A;  3VRN A;  4F59 A;  2OZO A;  2SRC A;  1CSZ A;  1K9A A;  1JYQ A;  3PSK A;  2EYY A;  4E93 A;  3PLF B;  2K79 B;  4DGX A;  1BKL A;  2L3T A;  4EY0 A;  2PLD A;  1YVH A;  1O4R A;  3PFV A;  2PTK A;  1RPY A;  2MC1 A;  2RMX A;  1SHD A;  1G83 A;  5HKY A;  1R1Q A;  1CWE A;  3CD3 A;  2EOB A;  1A08 A;  1CSY A;  1SPR A;  1LUI A;  3N84 A;  3IMJ A;  2PLE A;  2Y1M A;  1GHU A;  2CIA A;  2CI9 A;  4NWG A;  3VS3 A;  4JEG A;  4ROJ A;  1BLJ A;  1A1E A;  1KSW A;  1BF5 A;  4K44 A;  1SHB A;  2L4K A;  1M61 A;  1NZL A;  5DC4 A;  1NRV A;  4OHL A;  4F5A A;  2VIF A;  3PJP A;  4OHD A;  3HCK A;  3NHN A;  1BKM A;  4FL2 A;  2LQW A;  2EO3 A;  2LQN A;  1JU5 A;  5DF6 A;  4M4Z A;  1BFI A;  3M7F A;  5D0J A;  2CI8 A;  1FBZ A;  2HUW A;  1LKL A;  1CJ1 A;  5HKW A;  3OB1 B;  1FHS A;  1Y57 A;  1LUN A;  2IUI A;  4H34 A;  5HKZ A;  2H5K A;  1BHF A;  1LUK A;  4E68 A;  4TZI A;  1O4K A;  2MRJ A;  2LNW A;  5AXI A;  3BUM B;  1UUS A;  3VRR A;  3QWY A;  2H46 E;  4DGP A;  2DCR A;  2DLZ A;  1AYC A;  3GXX A;  3EAC A;  1O4E A;  3VS1 A;  1AD5 A;  4NWF A;  1LKK A;  1B47 A;  1X27 A;  1O45 A;  1TCE A;  3VS4 A;  3EAZ A;  1P13 A;  1CWD L;  1O4J A;  1RQQ C;  2ETZ A;  1FU6 A;  1O43 A;  1QG1 E;  1XA6 A;  2GSB A;  3HIZ B;  1JYR A;  2EO6 A;  3PSJ A;  1F2F A;  1MIL A;  5IBS A;  3S8L A;  1ZFP E;  2L6K A;  4P9Z A;  5DC9 A;  1AOU F;  1UUR A;  1O4L A;  3TKZ A;  1BLK A;  4OHE A;  2Y1N A;  4X6S A;  3VGO A;  4K11 A;  2GE9 A;  5EHP A;  1OO3 A;  1FMK A;  2HDX A;  1A09 A;  1YVL A;  5BO4 A;  1LCK A;  2AOA A;  4OHH A;  1O42 A;  1SPS A;  1O4D A;  2FCI A;  3WA4 A;  2EYZ A;  4U17 A;  5EG3 B;  1X6C A;  1IJR A;  1A1B A;  2CR4 A;  2PNA A;  4A4C A;  2HDV A;  1O4C A;  1O48 A;  2EL8 A;  2C0O A;  2MRK A;  4JGH A;  2LCT A;  1OPK A;  1JYU A;  1A07 A;  1D4W A;  4GL9 E;  2IZV A;  3VS6 A;  3VRP A;  1O4P A;  3IMD A;  1O4O A;  1R1S A;  3CXL A;  1QAD A;  2C0T A;  4A4B A;  1M27 A;  3N7Y A;  5GJI A;  1BFJ A;  1O4G A;  1LCJ A;  4XZ1 A;  3VRQ A;  2DVJ A;  4GPL B;  5I6V A;  1BHH A;  1AOT F;  3GQI B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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