4K45A

Auto-inhibition and phosphorylation-induced activation of plc-gamma isozymes
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
102
structure length
102
Chain Sequence
QAESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
pubmed doi rcsb
molecule keywords 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ga
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
total genus 26
structure length 102
sequence length 102
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2013-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4k45A00
2XP1A 1O4EA 2EU0A 2C0IA 2DLYA 1YVLA 4NWFA 3IMDA 1A1AA 2RMXA 5HKWA 1D1ZA 1BHHB 1BLKA 2LQWA 4K2RA 3GQIB 2PTKA 1D4TA 1XA6A 1KC2A 1O4IA 4A4CA 5HKZA 1LCJA 5EELA 2EO6A 1O43A 1LKKA 2H5KA 3HIZB 3VRNA 1BG1A 2HUWA 1A09A 4ROJA 2KK6A 3OB2B 3QWYA 3UYOA 2CS0A 4L1BB 2HDVA 4FL2A 2DX0A 2EYZA 3VRPA 3VRZA 1LUKA 3PSKA 1BFIA 1FYRA 1O4JA 4OHHA 5EHRA 1D4WA 3EAZA 1GHUA 1KA6A 4DGXA 4K44A 1O4NA 2H8HA 4K11A 1MW4A 5AXIA 3OVEA 3VRQA 2DVJA 1O4CA 1O4HA 1OO3A 4E93A 1AOUF 3ZNIA 2MRKA 2C9WA 3BUNB 1HCSB 2C0OA 3S8LA 1O42A 2FO0A 2EL8A 1CJ1A 1O4OA 4F5AA 1LUMA 4EIHA 1OPKA 1RJAA 1FBZA 5D0JA 5IBSA 1PICA 1R1PA 2PNAA 3VRRA 3UF4A 1FU5A 1AD5A 1SHDA 1O4LA 3BUXB 3EACA 5CDWA 3GXXA 1SHAA 2L3TA 1JYRA 4H1OA 3PSJA 3OB1B 3CBLA 4H34A 1HCTB 5EHPA 1MILA 1H9OA 2JYQA 1QADA 3VS2A 4X6SA 1A81A 2K79B 1TCEA 2H46E 1AB2A 2EYYA 3TKZA 2RSYA 1AYAA 1A1CA 2CR4A 1O4PA 5EEQA 2YU7A 2LNWA 2MQIA 3S8NA 2PLEA 1JWOA 1AYBA 3MXYA 3N84A 1SPRA 2OQ1A 5KAZA 4GL9E 1SPSA 5GJHA 4U1PA 3VS4A 4A4BA 1UURA 4EY0A 4OHLA 2ETZA 2IZVA 4P9VA 3VRYA 4K45A 4JEGA 3C7IA 3HCKA 1M61A 1A08A 2L4KA 1WQUA 2AOAA 1A1EA 1CSZA 3US4A 3BUWB 2HCKA 2CBLA 1BM2A 1O4MA 5AULA 2DCRA 2YSXA 1OPLA 2SHPA 3HHMB 1LCKA 2VIFA 3IN8A 1RQQC 1X27A 1BFJA 3PQZA 1FU6A 2MK2A 1NZVA 1SHBA 4OHEA 2CRHA 2RORA 1BHFA 4GWFA 1I3ZA 3QWXX 3PFVA 5DF6A 1R1SA 1QCFA 2MRJA 2HMHA 2EKXA 3S8OA 1KSWA 1BF5A 2ABLA 4LUEA 3MXCA 2OZOA 1NRVA 1IS0A 1F1WA 2EO3A 2PLDA 1LUNA 1ZFPE 3KFJA 4JGHA 1A07A 2CI9A 3VS0A 1X6CA 1QG1E 2DM0A 3OP0A 2C0TA 1O4DA 5DC9A 2Y1NA 3T04A 1JU5A 2RVFA 3WA4A 4GPLB 3VS6A 1BKMA 2QMSA 3OV1A 1O44A 4QSYA 1K9AA 1AYCA 3TL0A 2FCIA 3BKBA 1IJRA 4JE4A 1AOTF 2L6KA 2Y1MA 3VS1A 1JYUA 3VROA 1LKLA 1TZEE 2EOBA 2CIAA 3NHNA 5BO4A 1O4KA 1O4FA 1FMKA 4F5BA 3PLFB 3VGOA 2IUGA 2B3OA 3VS5A 1B47A 5I6VA 4FL3A 4TZIA 4E68A 4WWQA 2AOBA 1O47A 4D8KA 5J3XA 4LUDA 3BUOB 5HKYA 4XZ0A 1FBVA 1Y57A 3N8MA 2PNBA 4F59A 1Z3KA 2CI8A 3VS7A 5GJIA 3PS5A 3K2MA 3IMJA 2LNXA 2IUIA 3BUMB 2AUGA 4NWGA 1M27A 3CWGA 1OO4A 1G83A 3IN7A 1O48A 2ECDA 2KNOA 3M7FA 1BKLA 5DC4A 4OHDA 2EYVA 1JYQA 3VS3A 1CSYA 2LCTA 1O4BA 1F2FA 1KA7A 4P9ZA 1YVHA 1BMBA 1NZLA 1FHSA 1SKJA 3N7YA 1O4RA 5DC0B 1O4GA 4OHIA 4U17A 4M4ZA 2Y3AB 1R1QA 2MC1A 3CD3A 1BLJA 1A1BA 1CWDL 1LUIA 3CXLA 2GSBA 3S9KA 3MAZA 1O41A 5IBMA 1UUSA 2SRCA 1O49A 2IUHA 2LQNA 2HDXA 1O4AA 1GRIA 1X0NA 4FBNA 1Y1UA 1P13A 1BHHA 1O46A 1O45A 3PJPA 3GXWA 2K7AB 1AYDA 5EG3B 2DLZA 4DGPA 1CWEA 1O4QA 1RPYA 4XZ1A 2BBUA 2GE9A
chains in the Genus database with same CATH superfamily
2XP1A 1O4EA 2EU0A 2C0IA 2DLYA 1YVLA 4NWFA 3IMDA 1A1AA 2RMXA 5HKWA 1D1ZA 1BHHB 1BLKA 2LQWA 4K2RA 3GQIB 2PTKA 1D4TA 1XA6A 1KC2A 1O4IA 4A4CA 5HKZA 1LCJA 5EELA 2EO6A 1O43A 1LKKA 2H5KA 3HIZB 3VRNA 1BG1A 2HUWA 1A09A 4ROJA 2KK6A 3OB2B 3QWYA 3UYOA 2CS0A 4L1BB 2HDVA 4FL2A 2DX0A 2EYZA 3VRPA 3VRZA 1LUKA 3PSKA 1BFIA 1FYRA 1O4JA 4OHHA 5EHRA 1D4WA 3EAZA 1GHUA 1KA6A 4DGXA 4K44A 1O4NA 2H8HA 4K11A 1MW4A 5AXIA 3OVEA 3VRQA 2DVJA 1O4CA 1O4HA 1OO3A 4E93A 1AOUF 3ZNIA 2MRKA 2C9WA 3BUNB 1HCSB 2C0OA 3S8LA 1O42A 2FO0A 2EL8A 1CJ1A 1O4OA 4F5AA 1LUMA 4EIHA 1OPKA 1RJAA 1FBZA 5D0JA 5IBSA 1PICA 1R1PA 2PNAA 3VRRA 3UF4A 1FU5A 3LYVA 1AD5A 1SHDA 1O4LA 3BUXB 3EACA 5CDWA 3GXXA 1SHAA 2L3TA 1JYRA 4H1OA 3PSJA 3OB1B 3CBLA 4H34A 1HCTB 5EHPA 1MILA 1H9OA 2JYQA 1QADA 3VS2A 4X6SA 1A81A 2K79B 1TCEA 2H46E 1AB2A 2EYYA 3TKZA 2RSYA 1AYAA 1A1CA 2CR4A 1O4PA 5EEQA 2YU7A 2LNWA 2MQIA 3S8NA 2PLEA 1JWOA 1AYBA 3MXYA 3N84A 1SPRA 2OQ1A 5KAZA 4GL9E 1SPSA 5GJHA 4U1PA 3VS4A 4A4BA 1UURA 4EY0A 4OHLA 2ETZA 2IZVA 4P9VA 3VRYA 4K45A 4JEGA 3C7IA 3HCKA 1M61A 1A08A 2L4KA 1WQUA 2AOAA 1A1EA 1CSZA 3US4A 3BUWB 2HCKA 2CBLA 1BM2A 1O4MA 5AULA 2DCRA 2YSXA 1OPLA 2SHPA 3HHMB 1LCKA 2VIFA 3IN8A 1RQQC 1X27A 1BFJA 3PQZA 1FU6A 3K2TA 2MK2A 1NZVA 1SHBA 4OHEA 2CRHA 2RORA 1BHFA 4GWFA 1I3ZA 3QWXX 3PFVA 5DF6A 1R1SA 1QCFA 2MRJA 2HMHA 2EKXA 3S8OA 1KSWA 1BF5A 2ABLA 4LUEA 3MXCA 2OZOA 1NRVA 1IS0A 1F1WA 2EO3A 2PLDA 1LUNA 1ZFPE 3KFJA 4JGHA 1A07A 2CI9A 3VS0A 1X6CA 1QG1E 2DM0A 3OP0A 2C0TA 1O4DA 5DC9A 2Y1NA 3T04A 1JU5A 2RVFA 3WA4A 4GPLB 3VS6A 1BKMA 2QMSA 3OV1A 1O44A 4QSYA 1K9AA 1AYCA 3TL0A 2FCIA 3BKBA 1IJRA 4JE4A 1AOTF 2L6KA 2Y1MA 3VS1A 1JYUA 2LRAA 3VROA 1LKLA 1TZEE 2EOBA 2CIAA 3NHNA 5BO4A 1O4KA 1O4FA 1FMKA 4F5BA 3PLFB 3VGOA 2IUGA 2B3OA 3VS5A 1B47A 5I6VA 4FL3A 4TZIA 4E68A 4WWQA 2AOBA 1O47A 4D8KA 5J3XA 4LUDA 3BUOB 5HKYA 4XZ0A 1FBVA 1Y57A 3N8MA 2PNBA 4F59A 1Z3KA 2CI8A 3VS7A 5GJIA 3PS5A 3K2MA 3IMJA 2LNXA 2IUIA 3BUMB 2AUGA 4NWGA 1M27A 3CWGA 1OO4A 1G83A 3IN7A 1O48A 2ECDA 2KNOA 3M7FA 1BKLA 5DC4A 4OHDA 2EYVA 1JYQA 3VS3A 1CSYA 2LCTA 1O4BA 1F2FA 1KA7A 4P9ZA 1YVHA 1BMBA 1NZLA 1FHSA 1SKJA 3N7YA 1O4RA 5DC0B 1O4GA 4OHIA 4U17A 4M4ZA 2Y3AB 1R1QA 2MC1A 3CD3A 1BLJA 1A1BA 1CWDL 1LUIA 3CXLA 2GSBA 3S9KA 3MAZA 1O41A 5IBMA 1UUSA 2SRCA 1O49A 2IUHA 2LQNA 2HDXA 1O4AA 1GRIA 1X0NA 4FBNA 1Y1UA 1P13A 1BHHA 1O46A 2KGYA 1O45A 3PJPA 3GXWA 2K7AB 1AYDA 5EG3B 2DLZA 4DGPA 1CWEA 1O4QA 1RPYA 4XZ1A 2BBUA 2GE9A
chains in the Genus database with same CATH topology
2XP1A 1O4EA 2EU0A 2C0IA 2DLYA 1YVLA 4NWFA 3IMDA 1A1AA 2RMXA 5HKWA 1D1ZA 1BHHB 1BLKA 2LQWA 4K2RA 3GQIB 2PTKA 1D4TA 1XA6A 1KC2A 1O4IA 4A4CA 5HKZA 1LCJA 5EELA 2EO6A 1O43A 1LKKA 2H5KA 3HIZB 3VRNA 1BG1A 2HUWA 1A09A 4ROJA 2KK6A 3OB2B 3QWYA 3UYOA 2CS0A 4L1BB 2HDVA 4FL2A 2DX0A 2EYZA 3VRPA 3VRZA 1LUKA 3PSKA 1BFIA 1FYRA 1O4JA 4OHHA 5EHRA 1D4WA 3EAZA 1GHUA 1KA6A 4DGXA 4K44A 1O4NA 2H8HA 4K11A 1MW4A 5AXIA 3OVEA 3VRQA 2DVJA 1O4CA 1O4HA 1OO3A 4E93A 1AOUF 3ZNIA 2MRKA 2C9WA 3BUNB 1HCSB 2C0OA 3S8LA 1O42A 2FO0A 2EL8A 1CJ1A 1O4OA 4F5AA 1LUMA 4EIHA 1OPKA 1RJAA 1FBZA 5D0JA 5IBSA 1PICA 1R1PA 2PNAA 3VRRA 3UF4A 1FU5A 1AD5A 1SHDA 1O4LA 3BUXB 3EACA 5CDWA 3GXXA 1SHAA 2L3TA 1JYRA 4H1OA 3PSJA 3OB1B 3CBLA 4H34A 1HCTB 5EHPA 1MILA 1H9OA 2JYQA 1QADA 3VS2A 4X6SA 1A81A 2K79B 1TCEA 2H46E 1AB2A 2EYYA 3TKZA 2RSYA 1AYAA 1A1CA 2CR4A 1O4PA 5EEQA 2YU7A 2LNWA 2MQIA 3S8NA 2PLEA 1JWOA 1AYBA 3MXYA 3N84A 1SPRA 2OQ1A 5KAZA 4GL9E 1SPSA 5GJHA 4U1PA 3VS4A 4A4BA 1UURA 4EY0A 4OHLA 2ETZA 2IZVA 4P9VA 3VRYA 4K45A 4JEGA 3C7IA 3HCKA 1M61A 1A08A 2L4KA 1WQUA 2AOAA 1A1EA 1CSZA 3US4A 3BUWB 2HCKA 2CBLA 1BM2A 1O4MA 5AULA 2DCRA 2YSXA 1OPLA 2SHPA 3HHMB 1LCKA 2VIFA 3IN8A 1RQQC 1X27A 1BFJA 3PQZA 1FU6A 2MK2A 1NZVA 1SHBA 4OHEA 2CRHA 2RORA 1BHFA 4GWFA 1I3ZA 3QWXX 3PFVA 5DF6A 1R1SA 1QCFA 2MRJA 2HMHA 2EKXA 3S8OA 1KSWA 1BF5A 2ABLA 4LUEA 3MXCA 2OZOA 1NRVA 1IS0A 1F1WA 2EO3A 2PLDA 1LUNA 1ZFPE 3KFJA 4JGHA 1A07A 2CI9A 3VS0A 1X6CA 1QG1E 2DM0A 3OP0A 2C0TA 1O4DA 5DC9A 2Y1NA 3T04A 1JU5A 2RVFA 3WA4A 4GPLB 3VS6A 1BKMA 2QMSA 3OV1A 1O44A 4QSYA 1K9AA 1AYCA 3TL0A 2FCIA 3BKBA 1IJRA 4JE4A 1AOTF 2L6KA 2Y1MA 3VS1A 1JYUA 3VROA 1LKLA 1TZEE 2EOBA 2CIAA 3NHNA 5BO4A 1O4KA 1O4FA 1FMKA 4F5BA 3PLFB 3VGOA 2IUGA 2B3OA 3VS5A 1B47A 5I6VA 4FL3A 4TZIA 4E68A 4WWQA 2AOBA 1O47A 4D8KA 5J3XA 4LUDA 3BUOB 5HKYA 4XZ0A 1FBVA 1Y57A 3N8MA 2PNBA 4F59A 1Z3KA 2CI8A 3VS7A 5GJIA 3PS5A 3K2MA 3IMJA 2LNXA 2IUIA 3BUMB 2AUGA 4NWGA 1M27A 3CWGA 1OO4A 1G83A 3IN7A 1O48A 2ECDA 2KNOA 3M7FA 1BKLA 5DC4A 4OHDA 2EYVA 1JYQA 3VS3A 1CSYA 2LCTA 1O4BA 1F2FA 1KA7A 4P9ZA 1YVHA 1BMBA 1NZLA 1FHSA 1SKJA 3N7YA 1O4RA 5DC0B 1O4GA 4OHIA 4U17A 4M4ZA 2Y3AB 1R1QA 2MC1A 3CD3A 1BLJA 1A1BA 1CWDL 1LUIA 3CXLA 2GSBA 3S9KA 3MAZA 1O41A 5IBMA 1UUSA 2SRCA 1O49A 2IUHA 2LQNA 2HDXA 1O4AA 1GRIA 1X0NA 4FBNA 1Y1UA 1P13A 1BHHA 1O46A 1O45A 3PJPA 3GXWA 2K7AB 1AYDA 5EG3B 2DLZA 4DGPA 1CWEA 1O4QA 1RPYA 4XZ1A 2BBUA 2GE9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XP1 A;  1O4E A;  2EU0 A;  2C0I A;  2DLY A;  1YVL A;  4NWF A;  3IMD A;  1A1A A;  2RMX A;  5HKW A;  1D1Z A;  1BHH B;  1BLK A;  2LQW A;  4K2R A;  3GQI B;  2PTK A;  1D4T A;  1XA6 A;  1KC2 A;  1O4I A;  4A4C A;  5HKZ A;  1LCJ A;  5EEL A;  2EO6 A;  1O43 A;  1LKK A;  2H5K A;  3HIZ B;  3VRN A;  1BG1 A;  2HUW A;  1A09 A;  4ROJ A;  2KK6 A;  3OB2 B;  3QWY A;  3UYO A;  2CS0 A;  4L1B B;  2HDV A;  4FL2 A;  2DX0 A;  2EYZ A;  3VRP A;  3VRZ A;  1LUK A;  3PSK A;  1BFI A;  1FYR A;  1O4J A;  4OHH A;  5EHR A;  1D4W A;  3EAZ A;  1GHU A;  1KA6 A;  4DGX A;  4K44 A;  1O4N A;  2H8H A;  4K11 A;  1MW4 A;  5AXI A;  3OVE A;  3VRQ A;  2DVJ A;  1O4C A;  1O4H A;  1OO3 A;  4E93 A;  1AOU F;  3ZNI A;  2MRK A;  2C9W A;  3BUN B;  1HCS B;  2C0O A;  3S8L A;  1O42 A;  2FO0 A;  2EL8 A;  1CJ1 A;  1O4O A;  4F5A A;  1LUM A;  4EIH A;  1OPK A;  1RJA A;  1FBZ A;  5D0J A;  5IBS A;  1PIC A;  1R1P A;  2PNA A;  3VRR A;  3UF4 A;  1FU5 A;  1AD5 A;  1SHD A;  1O4L A;  3BUX B;  3EAC A;  5CDW A;  3GXX A;  1SHA A;  2L3T A;  1JYR A;  4H1O A;  3PSJ A;  3OB1 B;  3CBL A;  4H34 A;  1HCT B;  5EHP A;  1MIL A;  1H9O A;  2JYQ A;  1QAD A;  3VS2 A;  4X6S A;  1A81 A;  2K79 B;  1TCE A;  2H46 E;  1AB2 A;  2EYY A;  3TKZ A;  2RSY A;  1AYA A;  1A1C A;  2CR4 A;  1O4P A;  5EEQ A;  2YU7 A;  2LNW A;  2MQI A;  3S8N A;  2PLE A;  1JWO A;  1AYB A;  3MXY A;  3N84 A;  1SPR A;  2OQ1 A;  5KAZ A;  4GL9 E;  1SPS A;  5GJH A;  4U1P A;  3VS4 A;  4A4B A;  1UUR A;  4EY0 A;  4OHL A;  2ETZ A;  2IZV A;  4P9V A;  3VRY A;  4K45 A;  4JEG A;  3C7I A;  3HCK A;  1M61 A;  1A08 A;  2L4K A;  1WQU A;  2AOA A;  1A1E A;  1CSZ A;  3US4 A;  3BUW B;  2HCK A;  2CBL A;  1BM2 A;  1O4M A;  5AUL A;  2DCR A;  2YSX A;  1OPL A;  2SHP A;  3HHM B;  1LCK A;  2VIF A;  3IN8 A;  1RQQ C;  1X27 A;  1BFJ A;  3PQZ A;  1FU6 A;  2MK2 A;  1NZV A;  1SHB A;  4OHE A;  2CRH A;  2ROR A;  1BHF A;  4GWF A;  1I3Z A;  3QWX X;  3PFV A;  5DF6 A;  1R1S A;  1QCF A;  2MRJ A;  2HMH A;  2EKX A;  3S8O A;  1KSW A;  1BF5 A;  2ABL A;  4LUE A;  3MXC A;  2OZO A;  1NRV A;  1IS0 A;  1F1W A;  2EO3 A;  2PLD A;  1LUN A;  1ZFP E;  3KFJ A;  4JGH A;  1A07 A;  2CI9 A;  3VS0 A;  1X6C A;  1QG1 E;  2DM0 A;  3OP0 A;  2C0T A;  1O4D A;  5DC9 A;  2Y1N A;  3T04 A;  1JU5 A;  2RVF A;  3WA4 A;  4GPL B;  3VS6 A;  1BKM A;  2QMS A;  3OV1 A;  1O44 A;  4QSY A;  1K9A A;  1AYC A;  3TL0 A;  2FCI A;  3BKB A;  1IJR A;  4JE4 A;  1AOT F;  2L6K A;  2Y1M A;  3VS1 A;  1JYU A;  3VRO A;  1LKL A;  1TZE E;  2EOB A;  2CIA A;  3NHN A;  5BO4 A;  1O4K A;  1O4F A;  1FMK A;  4F5B A;  3PLF B;  3VGO A;  2IUG A;  2B3O A;  3VS5 A;  1B47 A;  5I6V A;  4FL3 A;  4TZI A;  4E68 A;  4WWQ A;  2AOB A;  1O47 A;  4D8K A;  5J3X A;  4LUD A;  3BUO B;  5HKY A;  4XZ0 A;  1FBV A;  1Y57 A;  3N8M A;  2PNB A;  4F59 A;  1Z3K A;  2CI8 A;  3VS7 A;  5GJI A;  3PS5 A;  3K2M A;  3IMJ A;  2LNX A;  2IUI A;  3BUM B;  2AUG A;  4NWG A;  1M27 A;  3CWG A;  1OO4 A;  1G83 A;  3IN7 A;  1O48 A;  2ECD A;  2KNO A;  3M7F A;  1BKL A;  5DC4 A;  4OHD A;  2EYV A;  1JYQ A;  3VS3 A;  1CSY A;  2LCT A;  1O4B A;  1F2F A;  1KA7 A;  4P9Z A;  1YVH A;  1BMB A;  1NZL A;  1FHS A;  1SKJ A;  3N7Y A;  1O4R A;  5DC0 B;  1O4G A;  4OHI A;  4U17 A;  4M4Z A;  2Y3A B;  1R1Q A;  2MC1 A;  3CD3 A;  1BLJ A;  1A1B A;  1CWD L;  1LUI A;  3CXL A;  2GSB A;  3S9K A;  3MAZ A;  1O41 A;  5IBM A;  1UUS A;  2SRC A;  1O49 A;  2IUH A;  2LQN A;  2HDX A;  1O4A A;  1GRI A;  1X0N A;  4FBN A;  1Y1U A;  1P13 A;  1BHH A;  1O46 A;  1O45 A;  3PJP A;  3GXW A;  2K7A B;  1AYD A;  5EG3 B;  2DLZ A;  4DGP A;  1CWE A;  1O4Q A;  1RPY A;  4XZ1 A;  2BBU A;  2GE9 A; 
#chains in the Genus database with same CATH topology
 2XP1 A;  1O4E A;  2EU0 A;  2C0I A;  2DLY A;  1YVL A;  4NWF A;  3IMD A;  1A1A A;  2RMX A;  5HKW A;  1D1Z A;  1BHH B;  1BLK A;  2LQW A;  4K2R A;  3GQI B;  2PTK A;  1D4T A;  1XA6 A;  1KC2 A;  1O4I A;  4A4C A;  5HKZ A;  1LCJ A;  5EEL A;  2EO6 A;  1O43 A;  1LKK A;  2H5K A;  3HIZ B;  3VRN A;  1BG1 A;  2HUW A;  1A09 A;  4ROJ A;  2KK6 A;  3OB2 B;  3QWY A;  3UYO A;  2CS0 A;  4L1B B;  2HDV A;  4FL2 A;  2DX0 A;  2EYZ A;  3VRP A;  3VRZ A;  1LUK A;  3PSK A;  1BFI A;  1FYR A;  1O4J A;  4OHH A;  5EHR A;  1D4W A;  3EAZ A;  1GHU A;  1KA6 A;  4DGX A;  4K44 A;  1O4N A;  2H8H A;  4K11 A;  1MW4 A;  5AXI A;  3OVE A;  3VRQ A;  2DVJ A;  1O4C A;  1O4H A;  1OO3 A;  4E93 A;  1AOU F;  3ZNI A;  2MRK A;  2C9W A;  3BUN B;  1HCS B;  2C0O A;  3S8L A;  1O42 A;  2FO0 A;  2EL8 A;  1CJ1 A;  1O4O A;  4F5A A;  1LUM A;  4EIH A;  1OPK A;  1RJA A;  1FBZ A;  5D0J A;  5IBS A;  1PIC A;  1R1P A;  2PNA A;  3VRR A;  3UF4 A;  1FU5 A;  3LYV A;  1AD5 A;  1SHD A;  1O4L A;  3BUX B;  3EAC A;  5CDW A;  3GXX A;  1SHA A;  2L3T A;  1JYR A;  4H1O A;  3PSJ A;  3OB1 B;  3CBL A;  4H34 A;  1HCT B;  5EHP A;  1MIL A;  1H9O A;  2JYQ A;  1QAD A;  3VS2 A;  4X6S A;  1A81 A;  2K79 B;  1TCE A;  2H46 E;  1AB2 A;  2EYY A;  3TKZ A;  2RSY A;  1AYA A;  1A1C A;  2CR4 A;  1O4P A;  5EEQ A;  2YU7 A;  2LNW A;  2MQI A;  3S8N A;  2PLE A;  1JWO A;  1AYB A;  3MXY A;  3N84 A;  1SPR A;  2OQ1 A;  5KAZ A;  4GL9 E;  1SPS A;  5GJH A;  4U1P A;  3VS4 A;  4A4B A;  1UUR A;  4EY0 A;  4OHL A;  2ETZ A;  2IZV A;  4P9V A;  3VRY A;  4K45 A;  4JEG A;  3C7I A;  3HCK A;  1M61 A;  1A08 A;  2L4K A;  1WQU A;  2AOA A;  1A1E A;  1CSZ A;  3US4 A;  3BUW B;  2HCK A;  2CBL A;  1BM2 A;  1O4M A;  5AUL A;  2DCR A;  2YSX A;  1OPL A;  2SHP A;  3HHM B;  1LCK A;  2VIF A;  3IN8 A;  1RQQ C;  1X27 A;  1BFJ A;  3PQZ A;  1FU6 A;  3K2T A;  2MK2 A;  1NZV A;  1SHB A;  4OHE A;  2CRH A;  2ROR A;  1BHF A;  4GWF A;  1I3Z A;  3QWX X;  3PFV A;  5DF6 A;  1R1S A;  1QCF A;  2MRJ A;  2HMH A;  2EKX A;  3S8O A;  1KSW A;  1BF5 A;  2ABL A;  4LUE A;  3MXC A;  2OZO A;  1NRV A;  1IS0 A;  1F1W A;  2EO3 A;  2PLD A;  1LUN A;  1ZFP E;  3KFJ A;  4JGH A;  1A07 A;  2CI9 A;  3VS0 A;  1X6C A;  1QG1 E;  2DM0 A;  3OP0 A;  2C0T A;  1O4D A;  5DC9 A;  2Y1N A;  3T04 A;  1JU5 A;  2RVF A;  3WA4 A;  4GPL B;  3VS6 A;  1BKM A;  2QMS A;  3OV1 A;  1O44 A;  4QSY A;  1K9A A;  1AYC A;  3TL0 A;  2FCI A;  3BKB A;  1IJR A;  4JE4 A;  1AOT F;  2L6K A;  2Y1M A;  3VS1 A;  1JYU A;  2LRA A;  3VRO A;  1LKL A;  1TZE E;  2EOB A;  2CIA A;  3NHN A;  5BO4 A;  1O4K A;  1O4F A;  1FMK A;  4F5B A;  3PLF B;  3VGO A;  2IUG A;  2B3O A;  3VS5 A;  1B47 A;  5I6V A;  4FL3 A;  4TZI A;  4E68 A;  4WWQ A;  2AOB A;  1O47 A;  4D8K A;  5J3X A;  4LUD A;  3BUO B;  5HKY A;  4XZ0 A;  1FBV A;  1Y57 A;  3N8M A;  2PNB A;  4F59 A;  1Z3K A;  2CI8 A;  3VS7 A;  5GJI A;  3PS5 A;  3K2M A;  3IMJ A;  2LNX A;  2IUI A;  3BUM B;  2AUG A;  4NWG A;  1M27 A;  3CWG A;  1OO4 A;  1G83 A;  3IN7 A;  1O48 A;  2ECD A;  2KNO A;  3M7F A;  1BKL A;  5DC4 A;  4OHD A;  2EYV A;  1JYQ A;  3VS3 A;  1CSY A;  2LCT A;  1O4B A;  1F2F A;  1KA7 A;  4P9Z A;  1YVH A;  1BMB A;  1NZL A;  1FHS A;  1SKJ A;  3N7Y A;  1O4R A;  5DC0 B;  1O4G A;  4OHI A;  4U17 A;  4M4Z A;  2Y3A B;  1R1Q A;  2MC1 A;  3CD3 A;  1BLJ A;  1A1B A;  1CWD L;  1LUI A;  3CXL A;  2GSB A;  3S9K A;  3MAZ A;  1O41 A;  5IBM A;  1UUS A;  2SRC A;  1O49 A;  2IUH A;  2LQN A;  2HDX A;  1O4A A;  1GRI A;  1X0N A;  4FBN A;  1Y1U A;  1P13 A;  1BHH A;  1O46 A;  2KGY A;  1O45 A;  3PJP A;  3GXW A;  2K7A B;  1AYD A;  5EG3 B;  2DLZ A;  4DGP A;  1CWE A;  1O4Q A;  1RPY A;  4XZ1 A;  2BBU A;  2GE9 A; 
#chains in the Genus database with same CATH homology
 2XP1 A;  1O4E A;  2EU0 A;  2C0I A;  2DLY A;  1YVL A;  4NWF A;  3IMD A;  1A1A A;  2RMX A;  5HKW A;  1D1Z A;  1BHH B;  1BLK A;  2LQW A;  4K2R A;  3GQI B;  2PTK A;  1D4T A;  1XA6 A;  1KC2 A;  1O4I A;  4A4C A;  5HKZ A;  1LCJ A;  5EEL A;  2EO6 A;  1O43 A;  1LKK A;  2H5K A;  3HIZ B;  3VRN A;  1BG1 A;  2HUW A;  1A09 A;  4ROJ A;  2KK6 A;  3OB2 B;  3QWY A;  3UYO A;  2CS0 A;  4L1B B;  2HDV A;  4FL2 A;  2DX0 A;  2EYZ A;  3VRP A;  3VRZ A;  1LUK A;  3PSK A;  1BFI A;  1FYR A;  1O4J A;  4OHH A;  5EHR A;  1D4W A;  3EAZ A;  1GHU A;  1KA6 A;  4DGX A;  4K44 A;  1O4N A;  2H8H A;  4K11 A;  1MW4 A;  5AXI A;  3OVE A;  3VRQ A;  2DVJ A;  1O4C A;  1O4H A;  1OO3 A;  4E93 A;  1AOU F;  3ZNI A;  2MRK A;  2C9W A;  3BUN B;  1HCS B;  2C0O A;  3S8L A;  1O42 A;  2FO0 A;  2EL8 A;  1CJ1 A;  1O4O A;  4F5A A;  1LUM A;  4EIH A;  1OPK A;  1RJA A;  1FBZ A;  5D0J A;  5IBS A;  1PIC A;  1R1P A;  2PNA A;  3VRR A;  3UF4 A;  1FU5 A;  1AD5 A;  1SHD A;  1O4L A;  3BUX B;  3EAC A;  5CDW A;  3GXX A;  1SHA A;  2L3T A;  1JYR A;  4H1O A;  3PSJ A;  3OB1 B;  3CBL A;  4H34 A;  1HCT B;  5EHP A;  1MIL A;  1H9O A;  2JYQ A;  1QAD A;  3VS2 A;  4X6S A;  1A81 A;  2K79 B;  1TCE A;  2H46 E;  1AB2 A;  2EYY A;  3TKZ A;  2RSY A;  1AYA A;  1A1C A;  2CR4 A;  1O4P A;  5EEQ A;  2YU7 A;  2LNW A;  2MQI A;  3S8N A;  2PLE A;  1JWO A;  1AYB A;  3MXY A;  3N84 A;  1SPR A;  2OQ1 A;  5KAZ A;  4GL9 E;  1SPS A;  5GJH A;  4U1P A;  3VS4 A;  4A4B A;  1UUR A;  4EY0 A;  4OHL A;  2ETZ A;  2IZV A;  4P9V A;  3VRY A;  4K45 A;  4JEG A;  3C7I A;  3HCK A;  1M61 A;  1A08 A;  2L4K A;  1WQU A;  2AOA A;  1A1E A;  1CSZ A;  3US4 A;  3BUW B;  2HCK A;  2CBL A;  1BM2 A;  1O4M A;  5AUL A;  2DCR A;  2YSX A;  1OPL A;  2SHP A;  3HHM B;  1LCK A;  2VIF A;  3IN8 A;  1RQQ C;  1X27 A;  1BFJ A;  3PQZ A;  1FU6 A;  2MK2 A;  1NZV A;  1SHB A;  4OHE A;  2CRH A;  2ROR A;  1BHF A;  4GWF A;  1I3Z A;  3QWX X;  3PFV A;  5DF6 A;  1R1S A;  1QCF A;  2MRJ A;  2HMH A;  2EKX A;  3S8O A;  1KSW A;  1BF5 A;  2ABL A;  4LUE A;  3MXC A;  2OZO A;  1NRV A;  1IS0 A;  1F1W A;  2EO3 A;  2PLD A;  1LUN A;  1ZFP E;  3KFJ A;  4JGH A;  1A07 A;  2CI9 A;  3VS0 A;  1X6C A;  1QG1 E;  2DM0 A;  3OP0 A;  2C0T A;  1O4D A;  5DC9 A;  2Y1N A;  3T04 A;  1JU5 A;  2RVF A;  3WA4 A;  4GPL B;  3VS6 A;  1BKM A;  2QMS A;  3OV1 A;  1O44 A;  4QSY A;  1K9A A;  1AYC A;  3TL0 A;  2FCI A;  3BKB A;  1IJR A;  4JE4 A;  1AOT F;  2L6K A;  2Y1M A;  3VS1 A;  1JYU A;  3VRO A;  1LKL A;  1TZE E;  2EOB A;  2CIA A;  3NHN A;  5BO4 A;  1O4K A;  1O4F A;  1FMK A;  4F5B A;  3PLF B;  3VGO A;  2IUG A;  2B3O A;  3VS5 A;  1B47 A;  5I6V A;  4FL3 A;  4TZI A;  4E68 A;  4WWQ A;  2AOB A;  1O47 A;  4D8K A;  5J3X A;  4LUD A;  3BUO B;  5HKY A;  4XZ0 A;  1FBV A;  1Y57 A;  3N8M A;  2PNB A;  4F59 A;  1Z3K A;  2CI8 A;  3VS7 A;  5GJI A;  3PS5 A;  3K2M A;  3IMJ A;  2LNX A;  2IUI A;  3BUM B;  2AUG A;  4NWG A;  1M27 A;  3CWG A;  1OO4 A;  1G83 A;  3IN7 A;  1O48 A;  2ECD A;  2KNO A;  3M7F A;  1BKL A;  5DC4 A;  4OHD A;  2EYV A;  1JYQ A;  3VS3 A;  1CSY A;  2LCT A;  1O4B A;  1F2F A;  1KA7 A;  4P9Z A;  1YVH A;  1BMB A;  1NZL A;  1FHS A;  1SKJ A;  3N7Y A;  1O4R A;  5DC0 B;  1O4G A;  4OHI A;  4U17 A;  4M4Z A;  2Y3A B;  1R1Q A;  2MC1 A;  3CD3 A;  1BLJ A;  1A1B A;  1CWD L;  1LUI A;  3CXL A;  2GSB A;  3S9K A;  3MAZ A;  1O41 A;  5IBM A;  1UUS A;  2SRC A;  1O49 A;  2IUH A;  2LQN A;  2HDX A;  1O4A A;  1GRI A;  1X0N A;  4FBN A;  1Y1U A;  1P13 A;  1BHH A;  1O46 A;  1O45 A;  3PJP A;  3GXW A;  2K7A B;  1AYD A;  5EG3 B;  2DLZ A;  4DGP A;  1CWE A;  1O4Q A;  1RPY A;  4XZ1 A;  2BBU A;  2GE9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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