1RQQC

Crystal structure of the insulin receptor kinase in complex with the sh2 domain of aps
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
85
structure length
83
Chain Sequence
LELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGQCHVQHLWFQSVFDMLRHF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
pubmed doi rcsb
molecule keywords Insulin receptor
molecule tags Transferase/signaling protein
source organism Homo sapiens
total genus 26
structure length 83
sequence length 85
chains with identical sequence D
ec nomenclature
pdb deposition date 2003-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1rqqC00
3BUOB 3PQZA 1A1CA 2CRHA 1BHFA 2QMSA 1R1SA 1TZEE 1O4PA 3TKZA 2CI9A 2SHPA 3N84A 4E68A 2IUIA 4OHDA 4FBNA 3IMJA 3MXCA 1BM2A 1RQQC 3OV1A 3VRZA 3US4A 2H5KA 4OHLA 2LQWA 4OHEA 2KK6A 2JYQA 2RORA 1FU6A 4X6SA 3VGOA 1KC2A 4F59A 2LCTA 2ETZA 2DM0A 1RJAA 3VS5A 1FBZA 1SHAA 5EEQA 1O4KA 1R1QA 2AUGA 1Z3KA 1PICA 2C0IA 4K44A 4F5AA 1BG1A 3OB2B 2PNBA 3T04A 4NWFA 1BFIA 1OPKA 1O4JA 1JWOA 2CR4A 2ABLA 2EKXA 4K2RA 3WA4A 3VS3A 1JYQA 4GPLB 3VS6A 2PTKA 1BFJA 2FCIA 2EL8A 3PSKA 1IS0A 2DCRA 1LUMA 1CWDL 2H8HA 2GE9A 3VS4A 5GJHA 2LQNA 1D4WA 4OHIA 3BUMB 3KFJA 1FYRA 1KA7A 1O4EA 1HCSB 1BKLA 3PJPA 3TL0A 1O4GA 3QWYA 4XZ0A 5GJIA 3K2MA 1R1PA 3BUXB 3S8NA 1O46A 1UUSA 4EY0A 3PSJA 2HDVA 1BMBA 2KNOA 1GHUA 1O4AA 2EO3A 2DLZA 4U1PA 1O48A 3CXLA 1RPYA 1A1BA 4M4ZA 2CI8A 3MAZA 2EYVA 1KSWA 1OO3A 2HMHA 5EG3B 1I3ZA 4A4BA 2MQIA 1D4TA 1MILA 1MW4A 1CJ1A 1O4BA 3MXYA 4FL3A 1FBVA 1A1EA 2HDXA 4FL2A 1NZLA 3IMDA 5DF6A 4QSYA 4P9ZA 3GXWA 3PLFB 2LNWA 3N7YA 2EU0A 1X0NA 4A4CA 3HIZB 1FU5A 1CSYA 4GL9E 1G83A 3UF4A 1B47A 2SRCA 1CSZA 3VRNA 2MC1A 1O43A 2PLEA 4JEGA 2CBLA 3IN7A 2Y3AB 3C7IA 1LCKA 2K79B 2IZVA 3ZNIA 2Y1NA 1O42A 2CS0A 4GWFA 1NRVA 1Y57A 2YSXA 3NHNA 5AXIA 4TZIA 2MRKA 1YVLA 1F1WA 5HKYA 1JYRA 3VRQA 2IUHA 2MRJA 1P13A 1JU5A 2AOAA 1LUIA 1D1ZA 2BBUA 1JYUA 3BUNB 2EYYA 3CWGA 5IBSA 5KAZA 4K45A 2YU7A 2PLDA 4DGXA 3OVEA 3VROA 5J3XA 5D0JA 1X6CA 1AD5A 1GRIA 1K9AA 1QG1E 1SHBA 2DX0A 1OPLA 1TCEA 1O47A 2HUWA 2DLYA 5EELA 3N8MA 2IUGA 5I6VA 1M61A 1O4QA 5AULA 4NWGA 3VS7A 2MK2A 1A08A 3OP0A 4P9VA 3PFVA 3UYOA 1O4DA 1AYCA 1O45A 4D8KA 2AOBA 2GSBA 1O44A 1FMKA 3EAZA 3M7FA 3S8LA 1LUNA 1O4RA 1BHHB 2RSYA 4EIHA 1IJRA 1AOTF 2OZOA 2OQ1A 1O4IA 1A1AA 2EO6A 3OB1B 1O4OA 2L6KA 3BUWB 5BO4A 4K11A 1O4HA 1BKMA 1A81A 1XA6A 4U17A 1LKKA 4LUEA 2B3OA 3VS2A 3S8OA 1LUKA 1QCFA 1BLKA 1O4NA 4OHHA 1OO4A 3QWXX 5IBMA 2HCKA 3HCKA 4JGHA 1BHHA 2Y1MA 4F5BA 1F2FA 1AYBA 1A09A 2VIFA 1KA6A 1LKLA 1O4CA 5EHRA 2ECDA 3IN8A 1A07A 3HHMB 1WQUA 1H9OA 3VRRA 1O4FA 2EOBA 3VRYA 4E93A 4WWQA 2H46E 1X27A 2C0TA 4H34A 3CD3A 1QADA 2XP1A 1HCTB 3S9KA 1SPSA 1YVHA 3EACA 2EYZA 1BLJA 5HKWA 1M27A 3GXXA 1SHDA 1AOUF 5DC0B 1O49A 2FO0A 2RVFA 1O4MA 1AYAA 4JE4A 1BF5A 2L3TA 1Y1UA 5HKZA 1ZFPE 4DGPA 3BKBA 1CWEA 2C0OA 2CIAA 2RMXA 4L1BB 3VS0A 4ROJA 5DC4A 3CBLA 4XZ1A 1O4LA 1SKJA 3PS5A 1FHSA 1LCJA 1O41A 2K7AB 5DC9A 2PNAA 1SPRA 2C9WA 1UURA 2DVJA 4LUDA 5EHPA 1AYDA 3GQIB 1NZVA 2L4KA 3VRPA 4H1OA 5CDWA 1AB2A 3VS1A 2LNXA
chains in the Genus database with same CATH superfamily
3BUOB 3PQZA 1A1CA 2CRHA 1BHFA 2QMSA 1R1SA 1TZEE 1O4PA 3TKZA 2CI9A 2SHPA 3N84A 4E68A 2IUIA 4OHDA 4FBNA 3IMJA 3MXCA 1BM2A 1RQQC 3K2TA 3OV1A 3VRZA 3US4A 2H5KA 4OHLA 2LQWA 4OHEA 2KK6A 2JYQA 2RORA 1FU6A 4X6SA 3VGOA 1KC2A 4F59A 2LCTA 2ETZA 2DM0A 1RJAA 3VS5A 1FBZA 1SHAA 5EEQA 1O4KA 1R1QA 2AUGA 1Z3KA 1PICA 2C0IA 4K44A 4F5AA 1BG1A 3OB2B 2PNBA 3T04A 4NWFA 1BFIA 1OPKA 1O4JA 1JWOA 2CR4A 2ABLA 2EKXA 4K2RA 3WA4A 3VS3A 1JYQA 4GPLB 3VS6A 2PTKA 1BFJA 2FCIA 2EL8A 3PSKA 1IS0A 2DCRA 1LUMA 1CWDL 2H8HA 2GE9A 3VS4A 5GJHA 2LQNA 1D4WA 4OHIA 3BUMB 3KFJA 1FYRA 1KA7A 1O4EA 1HCSB 1BKLA 3PJPA 3TL0A 1O4GA 3QWYA 4XZ0A 5GJIA 3K2MA 1R1PA 3BUXB 3S8NA 1O46A 1UUSA 4EY0A 3PSJA 2HDVA 1BMBA 2KNOA 1GHUA 1O4AA 2EO3A 2DLZA 4U1PA 1O48A 3CXLA 1RPYA 1A1BA 4M4ZA 2CI8A 3MAZA 2EYVA 1KSWA 1OO3A 2HMHA 5EG3B 1I3ZA 4A4BA 2MQIA 1D4TA 1MILA 1MW4A 1CJ1A 1O4BA 3MXYA 4FL3A 1FBVA 1A1EA 2HDXA 4FL2A 1NZLA 3IMDA 5DF6A 4QSYA 4P9ZA 3GXWA 3PLFB 2LNWA 3N7YA 2EU0A 1X0NA 4A4CA 3HIZB 1FU5A 1CSYA 4GL9E 1G83A 3UF4A 1B47A 2SRCA 1CSZA 3VRNA 2MC1A 1O43A 2PLEA 4JEGA 2CBLA 3IN7A 2Y3AB 3C7IA 1LCKA 2K79B 2IZVA 3ZNIA 2Y1NA 1O42A 2CS0A 4GWFA 1NRVA 1Y57A 2YSXA 3NHNA 5AXIA 4TZIA 2MRKA 1YVLA 1F1WA 5HKYA 1JYRA 3VRQA 2IUHA 2MRJA 1P13A 1JU5A 2AOAA 1LUIA 1D1ZA 2BBUA 1JYUA 3BUNB 2EYYA 3CWGA 5IBSA 5KAZA 4K45A 2YU7A 2PLDA 4DGXA 3OVEA 3VROA 5J3XA 5D0JA 1X6CA 1AD5A 1GRIA 1K9AA 1QG1E 1SHBA 2DX0A 1OPLA 1TCEA 1O47A 2HUWA 2DLYA 5EELA 3N8MA 2IUGA 5I6VA 1M61A 1O4QA 5AULA 4NWGA 3VS7A 2MK2A 1A08A 3OP0A 4P9VA 3PFVA 3UYOA 1O4DA 1AYCA 1O45A 4D8KA 2AOBA 2GSBA 2LRAA 1O44A 1FMKA 3EAZA 3M7FA 3S8LA 1LUNA 1O4RA 1BHHB 2RSYA 4EIHA 1IJRA 1AOTF 2OZOA 2OQ1A 1O4IA 1A1AA 2EO6A 3OB1B 1O4OA 2L6KA 3BUWB 5BO4A 4K11A 1O4HA 1BKMA 1A81A 1XA6A 4U17A 1LKKA 4LUEA 2B3OA 3VS2A 3S8OA 1LUKA 1QCFA 1BLKA 1O4NA 4OHHA 1OO4A 3QWXX 5IBMA 2HCKA 3HCKA 4JGHA 3LYVA 1BHHA 2Y1MA 4F5BA 1F2FA 1AYBA 1A09A 2VIFA 1KA6A 1LKLA 1O4CA 5EHRA 2ECDA 3IN8A 1A07A 3HHMB 1WQUA 1H9OA 3VRRA 1O4FA 2EOBA 3VRYA 4E93A 4WWQA 2H46E 1X27A 2C0TA 4H34A 3CD3A 1QADA 2XP1A 1HCTB 3S9KA 1SPSA 1YVHA 3EACA 2EYZA 1BLJA 5HKWA 1M27A 3GXXA 1SHDA 1AOUF 5DC0B 1O49A 2FO0A 2RVFA 1O4MA 1AYAA 4JE4A 1BF5A 2L3TA 1Y1UA 5HKZA 1ZFPE 4DGPA 3BKBA 1CWEA 2C0OA 2CIAA 2RMXA 4L1BB 3VS0A 4ROJA 2KGYA 5DC4A 3CBLA 4XZ1A 1O4LA 1SKJA 3PS5A 1FHSA 1LCJA 1O41A 2K7AB 5DC9A 2PNAA 1SPRA 2C9WA 1UURA 2DVJA 4LUDA 5EHPA 1AYDA 3GQIB 1NZVA 2L4KA 3VRPA 4H1OA 5CDWA 1AB2A 3VS1A 2LNXA
chains in the Genus database with same CATH topology
3BUOB 3PQZA 1A1CA 2CRHA 1BHFA 2QMSA 1R1SA 1TZEE 1O4PA 3TKZA 2CI9A 2SHPA 3N84A 4E68A 2IUIA 4OHDA 4FBNA 3IMJA 3MXCA 1BM2A 1RQQC 3OV1A 3VRZA 3US4A 2H5KA 4OHLA 2LQWA 4OHEA 2KK6A 2JYQA 2RORA 1FU6A 4X6SA 3VGOA 1KC2A 4F59A 2LCTA 2ETZA 2DM0A 1RJAA 3VS5A 1FBZA 1SHAA 5EEQA 1O4KA 1R1QA 2AUGA 1Z3KA 1PICA 2C0IA 4K44A 4F5AA 1BG1A 3OB2B 2PNBA 3T04A 4NWFA 1BFIA 1OPKA 1O4JA 1JWOA 2CR4A 2ABLA 2EKXA 4K2RA 3WA4A 3VS3A 1JYQA 4GPLB 3VS6A 2PTKA 1BFJA 2FCIA 2EL8A 3PSKA 1IS0A 2DCRA 1LUMA 1CWDL 2H8HA 2GE9A 3VS4A 5GJHA 2LQNA 1D4WA 4OHIA 3BUMB 3KFJA 1FYRA 1KA7A 1O4EA 1HCSB 1BKLA 3PJPA 3TL0A 1O4GA 3QWYA 4XZ0A 5GJIA 3K2MA 1R1PA 3BUXB 3S8NA 1O46A 1UUSA 4EY0A 3PSJA 2HDVA 1BMBA 2KNOA 1GHUA 1O4AA 2EO3A 2DLZA 4U1PA 1O48A 3CXLA 1RPYA 1A1BA 4M4ZA 2CI8A 3MAZA 2EYVA 1KSWA 1OO3A 2HMHA 5EG3B 1I3ZA 4A4BA 2MQIA 1D4TA 1MILA 1MW4A 1CJ1A 1O4BA 3MXYA 4FL3A 1FBVA 1A1EA 2HDXA 4FL2A 1NZLA 3IMDA 5DF6A 4QSYA 4P9ZA 3GXWA 3PLFB 2LNWA 3N7YA 2EU0A 1X0NA 4A4CA 3HIZB 1FU5A 1CSYA 4GL9E 1G83A 3UF4A 1B47A 2SRCA 1CSZA 3VRNA 2MC1A 1O43A 2PLEA 4JEGA 2CBLA 3IN7A 2Y3AB 3C7IA 1LCKA 2K79B 2IZVA 3ZNIA 2Y1NA 1O42A 2CS0A 4GWFA 1NRVA 1Y57A 2YSXA 3NHNA 5AXIA 4TZIA 2MRKA 1YVLA 1F1WA 5HKYA 1JYRA 3VRQA 2IUHA 2MRJA 1P13A 1JU5A 2AOAA 1LUIA 1D1ZA 2BBUA 1JYUA 3BUNB 2EYYA 3CWGA 5IBSA 5KAZA 4K45A 2YU7A 2PLDA 4DGXA 3OVEA 3VROA 5J3XA 5D0JA 1X6CA 1AD5A 1GRIA 1K9AA 1QG1E 1SHBA 2DX0A 1OPLA 1TCEA 1O47A 2HUWA 2DLYA 5EELA 3N8MA 2IUGA 5I6VA 1M61A 1O4QA 5AULA 4NWGA 3VS7A 2MK2A 1A08A 3OP0A 4P9VA 3PFVA 3UYOA 1O4DA 1AYCA 1O45A 4D8KA 2AOBA 2GSBA 1O44A 1FMKA 3EAZA 3M7FA 3S8LA 1LUNA 1O4RA 1BHHB 2RSYA 4EIHA 1IJRA 1AOTF 2OZOA 2OQ1A 1O4IA 1A1AA 2EO6A 3OB1B 1O4OA 2L6KA 3BUWB 5BO4A 4K11A 1O4HA 1BKMA 1A81A 1XA6A 4U17A 1LKKA 4LUEA 2B3OA 3VS2A 3S8OA 1LUKA 1QCFA 1BLKA 1O4NA 4OHHA 1OO4A 3QWXX 5IBMA 2HCKA 3HCKA 4JGHA 1BHHA 2Y1MA 4F5BA 1F2FA 1AYBA 1A09A 2VIFA 1KA6A 1LKLA 1O4CA 5EHRA 2ECDA 3IN8A 1A07A 3HHMB 1WQUA 1H9OA 3VRRA 1O4FA 2EOBA 3VRYA 4E93A 4WWQA 2H46E 1X27A 2C0TA 4H34A 3CD3A 1QADA 2XP1A 1HCTB 3S9KA 1SPSA 1YVHA 3EACA 2EYZA 1BLJA 5HKWA 1M27A 3GXXA 1SHDA 1AOUF 5DC0B 1O49A 2FO0A 2RVFA 1O4MA 1AYAA 4JE4A 1BF5A 2L3TA 1Y1UA 5HKZA 1ZFPE 4DGPA 3BKBA 1CWEA 2C0OA 2CIAA 2RMXA 4L1BB 3VS0A 4ROJA 5DC4A 3CBLA 4XZ1A 1O4LA 1SKJA 3PS5A 1FHSA 1LCJA 1O41A 2K7AB 5DC9A 2PNAA 1SPRA 2C9WA 1UURA 2DVJA 4LUDA 5EHPA 1AYDA 3GQIB 1NZVA 2L4KA 3VRPA 4H1OA 5CDWA 1AB2A 3VS1A 2LNXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BUO B;  3PQZ A;  1A1C A;  2CRH A;  1BHF A;  2QMS A;  1R1S A;  1TZE E;  1O4P A;  3TKZ A;  2CI9 A;  2SHP A;  3N84 A;  4E68 A;  2IUI A;  4OHD A;  4FBN A;  3IMJ A;  3MXC A;  1BM2 A;  1RQQ C;  3OV1 A;  3VRZ A;  3US4 A;  2H5K A;  4OHL A;  2LQW A;  4OHE A;  2KK6 A;  2JYQ A;  2ROR A;  1FU6 A;  4X6S A;  3VGO A;  1KC2 A;  4F59 A;  2LCT A;  2ETZ A;  2DM0 A;  1RJA A;  3VS5 A;  1FBZ A;  1SHA A;  5EEQ A;  1O4K A;  1R1Q A;  2AUG A;  1Z3K A;  1PIC A;  2C0I A;  4K44 A;  4F5A A;  1BG1 A;  3OB2 B;  2PNB A;  3T04 A;  4NWF A;  1BFI A;  1OPK A;  1O4J A;  1JWO A;  2CR4 A;  2ABL A;  2EKX A;  4K2R A;  3WA4 A;  3VS3 A;  1JYQ A;  4GPL B;  3VS6 A;  2PTK A;  1BFJ A;  2FCI A;  2EL8 A;  3PSK A;  1IS0 A;  2DCR A;  1LUM A;  1CWD L;  2H8H A;  2GE9 A;  3VS4 A;  5GJH A;  2LQN A;  1D4W A;  4OHI A;  3BUM B;  3KFJ A;  1FYR A;  1KA7 A;  1O4E A;  1HCS B;  1BKL A;  3PJP A;  3TL0 A;  1O4G A;  3QWY A;  4XZ0 A;  5GJI A;  3K2M A;  1R1P A;  3BUX B;  3S8N A;  1O46 A;  1UUS A;  4EY0 A;  3PSJ A;  2HDV A;  1BMB A;  2KNO A;  1GHU A;  1O4A A;  2EO3 A;  2DLZ A;  4U1P A;  1O48 A;  3CXL A;  1RPY A;  1A1B A;  4M4Z A;  2CI8 A;  3MAZ A;  2EYV A;  1KSW A;  1OO3 A;  2HMH A;  5EG3 B;  1I3Z A;  4A4B A;  2MQI A;  1D4T A;  1MIL A;  1MW4 A;  1CJ1 A;  1O4B A;  3MXY A;  4FL3 A;  1FBV A;  1A1E A;  2HDX A;  4FL2 A;  1NZL A;  3IMD A;  5DF6 A;  4QSY A;  4P9Z A;  3GXW A;  3PLF B;  2LNW A;  3N7Y A;  2EU0 A;  1X0N A;  4A4C A;  3HIZ B;  1FU5 A;  1CSY A;  4GL9 E;  1G83 A;  3UF4 A;  1B47 A;  2SRC A;  1CSZ A;  3VRN A;  2MC1 A;  1O43 A;  2PLE A;  4JEG A;  2CBL A;  3IN7 A;  2Y3A B;  3C7I A;  1LCK A;  2K79 B;  2IZV A;  3ZNI A;  2Y1N A;  1O42 A;  2CS0 A;  4GWF A;  1NRV A;  1Y57 A;  2YSX A;  3NHN A;  5AXI A;  4TZI A;  2MRK A;  1YVL A;  1F1W A;  5HKY A;  1JYR A;  3VRQ A;  2IUH A;  2MRJ A;  1P13 A;  1JU5 A;  2AOA A;  1LUI A;  1D1Z A;  2BBU A;  1JYU A;  3BUN B;  2EYY A;  3CWG A;  5IBS A;  5KAZ A;  4K45 A;  2YU7 A;  2PLD A;  4DGX A;  3OVE A;  3VRO A;  5J3X A;  5D0J A;  1X6C A;  1AD5 A;  1GRI A;  1K9A A;  1QG1 E;  1SHB A;  2DX0 A;  1OPL A;  1TCE A;  1O47 A;  2HUW A;  2DLY A;  5EEL A;  3N8M A;  2IUG A;  5I6V A;  1M61 A;  1O4Q A;  5AUL A;  4NWG A;  3VS7 A;  2MK2 A;  1A08 A;  3OP0 A;  4P9V A;  3PFV A;  3UYO A;  1O4D A;  1AYC A;  1O45 A;  4D8K A;  2AOB A;  2GSB A;  1O44 A;  1FMK A;  3EAZ A;  3M7F A;  3S8L A;  1LUN A;  1O4R A;  1BHH B;  2RSY A;  4EIH A;  1IJR A;  1AOT F;  2OZO A;  2OQ1 A;  1O4I A;  1A1A A;  2EO6 A;  3OB1 B;  1O4O A;  2L6K A;  3BUW B;  5BO4 A;  4K11 A;  1O4H A;  1BKM A;  1A81 A;  1XA6 A;  4U17 A;  1LKK A;  4LUE A;  2B3O A;  3VS2 A;  3S8O A;  1LUK A;  1QCF A;  1BLK A;  1O4N A;  4OHH A;  1OO4 A;  3QWX X;  5IBM A;  2HCK A;  3HCK A;  4JGH A;  1BHH A;  2Y1M A;  4F5B A;  1F2F A;  1AYB A;  1A09 A;  2VIF A;  1KA6 A;  1LKL A;  1O4C A;  5EHR A;  2ECD A;  3IN8 A;  1A07 A;  3HHM B;  1WQU A;  1H9O A;  3VRR A;  1O4F A;  2EOB A;  3VRY A;  4E93 A;  4WWQ A;  2H46 E;  1X27 A;  2C0T A;  4H34 A;  3CD3 A;  1QAD A;  2XP1 A;  1HCT B;  3S9K A;  1SPS A;  1YVH A;  3EAC A;  2EYZ A;  1BLJ A;  5HKW A;  1M27 A;  3GXX A;  1SHD A;  1AOU F;  5DC0 B;  1O49 A;  2FO0 A;  2RVF A;  1O4M A;  1AYA A;  4JE4 A;  1BF5 A;  2L3T A;  1Y1U A;  5HKZ A;  1ZFP E;  4DGP A;  3BKB A;  1CWE A;  2C0O A;  2CIA A;  2RMX A;  4L1B B;  3VS0 A;  4ROJ A;  5DC4 A;  3CBL A;  4XZ1 A;  1O4L A;  1SKJ A;  3PS5 A;  1FHS A;  1LCJ A;  1O41 A;  2K7A B;  5DC9 A;  2PNA A;  1SPR A;  2C9W A;  1UUR A;  2DVJ A;  4LUD A;  5EHP A;  1AYD A;  3GQI B;  1NZV A;  2L4K A;  3VRP A;  4H1O A;  5CDW A;  1AB2 A;  3VS1 A;  2LNX A; 
#chains in the Genus database with same CATH topology
 3BUO B;  3PQZ A;  1A1C A;  2CRH A;  1BHF A;  2QMS A;  1R1S A;  1TZE E;  1O4P A;  3TKZ A;  2CI9 A;  2SHP A;  3N84 A;  4E68 A;  2IUI A;  4OHD A;  4FBN A;  3IMJ A;  3MXC A;  1BM2 A;  1RQQ C;  3K2T A;  3OV1 A;  3VRZ A;  3US4 A;  2H5K A;  4OHL A;  2LQW A;  4OHE A;  2KK6 A;  2JYQ A;  2ROR A;  1FU6 A;  4X6S A;  3VGO A;  1KC2 A;  4F59 A;  2LCT A;  2ETZ A;  2DM0 A;  1RJA A;  3VS5 A;  1FBZ A;  1SHA A;  5EEQ A;  1O4K A;  1R1Q A;  2AUG A;  1Z3K A;  1PIC A;  2C0I A;  4K44 A;  4F5A A;  1BG1 A;  3OB2 B;  2PNB A;  3T04 A;  4NWF A;  1BFI A;  1OPK A;  1O4J A;  1JWO A;  2CR4 A;  2ABL A;  2EKX A;  4K2R A;  3WA4 A;  3VS3 A;  1JYQ A;  4GPL B;  3VS6 A;  2PTK A;  1BFJ A;  2FCI A;  2EL8 A;  3PSK A;  1IS0 A;  2DCR A;  1LUM A;  1CWD L;  2H8H A;  2GE9 A;  3VS4 A;  5GJH A;  2LQN A;  1D4W A;  4OHI A;  3BUM B;  3KFJ A;  1FYR A;  1KA7 A;  1O4E A;  1HCS B;  1BKL A;  3PJP A;  3TL0 A;  1O4G A;  3QWY A;  4XZ0 A;  5GJI A;  3K2M A;  1R1P A;  3BUX B;  3S8N A;  1O46 A;  1UUS A;  4EY0 A;  3PSJ A;  2HDV A;  1BMB A;  2KNO A;  1GHU A;  1O4A A;  2EO3 A;  2DLZ A;  4U1P A;  1O48 A;  3CXL A;  1RPY A;  1A1B A;  4M4Z A;  2CI8 A;  3MAZ A;  2EYV A;  1KSW A;  1OO3 A;  2HMH A;  5EG3 B;  1I3Z A;  4A4B A;  2MQI A;  1D4T A;  1MIL A;  1MW4 A;  1CJ1 A;  1O4B A;  3MXY A;  4FL3 A;  1FBV A;  1A1E A;  2HDX A;  4FL2 A;  1NZL A;  3IMD A;  5DF6 A;  4QSY A;  4P9Z A;  3GXW A;  3PLF B;  2LNW A;  3N7Y A;  2EU0 A;  1X0N A;  4A4C A;  3HIZ B;  1FU5 A;  1CSY A;  4GL9 E;  1G83 A;  3UF4 A;  1B47 A;  2SRC A;  1CSZ A;  3VRN A;  2MC1 A;  1O43 A;  2PLE A;  4JEG A;  2CBL A;  3IN7 A;  2Y3A B;  3C7I A;  1LCK A;  2K79 B;  2IZV A;  3ZNI A;  2Y1N A;  1O42 A;  2CS0 A;  4GWF A;  1NRV A;  1Y57 A;  2YSX A;  3NHN A;  5AXI A;  4TZI A;  2MRK A;  1YVL A;  1F1W A;  5HKY A;  1JYR A;  3VRQ A;  2IUH A;  2MRJ A;  1P13 A;  1JU5 A;  2AOA A;  1LUI A;  1D1Z A;  2BBU A;  1JYU A;  3BUN B;  2EYY A;  3CWG A;  5IBS A;  5KAZ A;  4K45 A;  2YU7 A;  2PLD A;  4DGX A;  3OVE A;  3VRO A;  5J3X A;  5D0J A;  1X6C A;  1AD5 A;  1GRI A;  1K9A A;  1QG1 E;  1SHB A;  2DX0 A;  1OPL A;  1TCE A;  1O47 A;  2HUW A;  2DLY A;  5EEL A;  3N8M A;  2IUG A;  5I6V A;  1M61 A;  1O4Q A;  5AUL A;  4NWG A;  3VS7 A;  2MK2 A;  1A08 A;  3OP0 A;  4P9V A;  3PFV A;  3UYO A;  1O4D A;  1AYC A;  1O45 A;  4D8K A;  2AOB A;  2GSB A;  2LRA A;  1O44 A;  1FMK A;  3EAZ A;  3M7F A;  3S8L A;  1LUN A;  1O4R A;  1BHH B;  2RSY A;  4EIH A;  1IJR A;  1AOT F;  2OZO A;  2OQ1 A;  1O4I A;  1A1A A;  2EO6 A;  3OB1 B;  1O4O A;  2L6K A;  3BUW B;  5BO4 A;  4K11 A;  1O4H A;  1BKM A;  1A81 A;  1XA6 A;  4U17 A;  1LKK A;  4LUE A;  2B3O A;  3VS2 A;  3S8O A;  1LUK A;  1QCF A;  1BLK A;  1O4N A;  4OHH A;  1OO4 A;  3QWX X;  5IBM A;  2HCK A;  3HCK A;  4JGH A;  3LYV A;  1BHH A;  2Y1M A;  4F5B A;  1F2F A;  1AYB A;  1A09 A;  2VIF A;  1KA6 A;  1LKL A;  1O4C A;  5EHR A;  2ECD A;  3IN8 A;  1A07 A;  3HHM B;  1WQU A;  1H9O A;  3VRR A;  1O4F A;  2EOB A;  3VRY A;  4E93 A;  4WWQ A;  2H46 E;  1X27 A;  2C0T A;  4H34 A;  3CD3 A;  1QAD A;  2XP1 A;  1HCT B;  3S9K A;  1SPS A;  1YVH A;  3EAC A;  2EYZ A;  1BLJ A;  5HKW A;  1M27 A;  3GXX A;  1SHD A;  1AOU F;  5DC0 B;  1O49 A;  2FO0 A;  2RVF A;  1O4M A;  1AYA A;  4JE4 A;  1BF5 A;  2L3T A;  1Y1U A;  5HKZ A;  1ZFP E;  4DGP A;  3BKB A;  1CWE A;  2C0O A;  2CIA A;  2RMX A;  4L1B B;  3VS0 A;  4ROJ A;  2KGY A;  5DC4 A;  3CBL A;  4XZ1 A;  1O4L A;  1SKJ A;  3PS5 A;  1FHS A;  1LCJ A;  1O41 A;  2K7A B;  5DC9 A;  2PNA A;  1SPR A;  2C9W A;  1UUR A;  2DVJ A;  4LUD A;  5EHP A;  1AYD A;  3GQI B;  1NZV A;  2L4K A;  3VRP A;  4H1O A;  5CDW A;  1AB2 A;  3VS1 A;  2LNX A; 
#chains in the Genus database with same CATH homology
 3BUO B;  3PQZ A;  1A1C A;  2CRH A;  1BHF A;  2QMS A;  1R1S A;  1TZE E;  1O4P A;  3TKZ A;  2CI9 A;  2SHP A;  3N84 A;  4E68 A;  2IUI A;  4OHD A;  4FBN A;  3IMJ A;  3MXC A;  1BM2 A;  1RQQ C;  3OV1 A;  3VRZ A;  3US4 A;  2H5K A;  4OHL A;  2LQW A;  4OHE A;  2KK6 A;  2JYQ A;  2ROR A;  1FU6 A;  4X6S A;  3VGO A;  1KC2 A;  4F59 A;  2LCT A;  2ETZ A;  2DM0 A;  1RJA A;  3VS5 A;  1FBZ A;  1SHA A;  5EEQ A;  1O4K A;  1R1Q A;  2AUG A;  1Z3K A;  1PIC A;  2C0I A;  4K44 A;  4F5A A;  1BG1 A;  3OB2 B;  2PNB A;  3T04 A;  4NWF A;  1BFI A;  1OPK A;  1O4J A;  1JWO A;  2CR4 A;  2ABL A;  2EKX A;  4K2R A;  3WA4 A;  3VS3 A;  1JYQ A;  4GPL B;  3VS6 A;  2PTK A;  1BFJ A;  2FCI A;  2EL8 A;  3PSK A;  1IS0 A;  2DCR A;  1LUM A;  1CWD L;  2H8H A;  2GE9 A;  3VS4 A;  5GJH A;  2LQN A;  1D4W A;  4OHI A;  3BUM B;  3KFJ A;  1FYR A;  1KA7 A;  1O4E A;  1HCS B;  1BKL A;  3PJP A;  3TL0 A;  1O4G A;  3QWY A;  4XZ0 A;  5GJI A;  3K2M A;  1R1P A;  3BUX B;  3S8N A;  1O46 A;  1UUS A;  4EY0 A;  3PSJ A;  2HDV A;  1BMB A;  2KNO A;  1GHU A;  1O4A A;  2EO3 A;  2DLZ A;  4U1P A;  1O48 A;  3CXL A;  1RPY A;  1A1B A;  4M4Z A;  2CI8 A;  3MAZ A;  2EYV A;  1KSW A;  1OO3 A;  2HMH A;  5EG3 B;  1I3Z A;  4A4B A;  2MQI A;  1D4T A;  1MIL A;  1MW4 A;  1CJ1 A;  1O4B A;  3MXY A;  4FL3 A;  1FBV A;  1A1E A;  2HDX A;  4FL2 A;  1NZL A;  3IMD A;  5DF6 A;  4QSY A;  4P9Z A;  3GXW A;  3PLF B;  2LNW A;  3N7Y A;  2EU0 A;  1X0N A;  4A4C A;  3HIZ B;  1FU5 A;  1CSY A;  4GL9 E;  1G83 A;  3UF4 A;  1B47 A;  2SRC A;  1CSZ A;  3VRN A;  2MC1 A;  1O43 A;  2PLE A;  4JEG A;  2CBL A;  3IN7 A;  2Y3A B;  3C7I A;  1LCK A;  2K79 B;  2IZV A;  3ZNI A;  2Y1N A;  1O42 A;  2CS0 A;  4GWF A;  1NRV A;  1Y57 A;  2YSX A;  3NHN A;  5AXI A;  4TZI A;  2MRK A;  1YVL A;  1F1W A;  5HKY A;  1JYR A;  3VRQ A;  2IUH A;  2MRJ A;  1P13 A;  1JU5 A;  2AOA A;  1LUI A;  1D1Z A;  2BBU A;  1JYU A;  3BUN B;  2EYY A;  3CWG A;  5IBS A;  5KAZ A;  4K45 A;  2YU7 A;  2PLD A;  4DGX A;  3OVE A;  3VRO A;  5J3X A;  5D0J A;  1X6C A;  1AD5 A;  1GRI A;  1K9A A;  1QG1 E;  1SHB A;  2DX0 A;  1OPL A;  1TCE A;  1O47 A;  2HUW A;  2DLY A;  5EEL A;  3N8M A;  2IUG A;  5I6V A;  1M61 A;  1O4Q A;  5AUL A;  4NWG A;  3VS7 A;  2MK2 A;  1A08 A;  3OP0 A;  4P9V A;  3PFV A;  3UYO A;  1O4D A;  1AYC A;  1O45 A;  4D8K A;  2AOB A;  2GSB A;  1O44 A;  1FMK A;  3EAZ A;  3M7F A;  3S8L A;  1LUN A;  1O4R A;  1BHH B;  2RSY A;  4EIH A;  1IJR A;  1AOT F;  2OZO A;  2OQ1 A;  1O4I A;  1A1A A;  2EO6 A;  3OB1 B;  1O4O A;  2L6K A;  3BUW B;  5BO4 A;  4K11 A;  1O4H A;  1BKM A;  1A81 A;  1XA6 A;  4U17 A;  1LKK A;  4LUE A;  2B3O A;  3VS2 A;  3S8O A;  1LUK A;  1QCF A;  1BLK A;  1O4N A;  4OHH A;  1OO4 A;  3QWX X;  5IBM A;  2HCK A;  3HCK A;  4JGH A;  1BHH A;  2Y1M A;  4F5B A;  1F2F A;  1AYB A;  1A09 A;  2VIF A;  1KA6 A;  1LKL A;  1O4C A;  5EHR A;  2ECD A;  3IN8 A;  1A07 A;  3HHM B;  1WQU A;  1H9O A;  3VRR A;  1O4F A;  2EOB A;  3VRY A;  4E93 A;  4WWQ A;  2H46 E;  1X27 A;  2C0T A;  4H34 A;  3CD3 A;  1QAD A;  2XP1 A;  1HCT B;  3S9K A;  1SPS A;  1YVH A;  3EAC A;  2EYZ A;  1BLJ A;  5HKW A;  1M27 A;  3GXX A;  1SHD A;  1AOU F;  5DC0 B;  1O49 A;  2FO0 A;  2RVF A;  1O4M A;  1AYA A;  4JE4 A;  1BF5 A;  2L3T A;  1Y1U A;  5HKZ A;  1ZFP E;  4DGP A;  3BKB A;  1CWE A;  2C0O A;  2CIA A;  2RMX A;  4L1B B;  3VS0 A;  4ROJ A;  5DC4 A;  3CBL A;  4XZ1 A;  1O4L A;  1SKJ A;  3PS5 A;  1FHS A;  1LCJ A;  1O41 A;  2K7A B;  5DC9 A;  2PNA A;  1SPR A;  2C9W A;  1UUR A;  2DVJ A;  4LUD A;  5EHP A;  1AYD A;  3GQI B;  1NZV A;  2L4K A;  3VRP A;  4H1O A;  5CDW A;  1AB2 A;  3VS1 A;  2LNX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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