4X6SA

Grb7 sh2 domain with phosphotyrosine mimetic inhibitor peptide
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
106
structure length
106
Chain Sequence
AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
molecule tags Signaling protein/inhibitor
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 7
total genus 25
structure length 106
sequence length 106
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4x6sA00
1QG1E 3N84A 5EEQA 2XP1A 5IBSA 3BUWB 3CBLA 1BKLA 2YU7A 2CS0A 2HDXA 1B47A 1MILA 2HMHA 2GSBA 4TZIA 1FYRA 1P13A 3K2MA 4F59A 4GWFA 1M27A 2ECDA 1CWEA 1FU6A 1H9OA 4OHIA 1BLJA 2LQWA 5BO4A 1LUMA 1R1QA 3GXXA 3BUNB 1KSWA 1BFIA 2IUIA 2EOBA 2L3TA 1AD5A 1BLKA 1BHHB 1ZFPE 1M61A 1O4JA 1FBZA 4FL2A 1UURA 2JYQA 1AYDA 5I6VA 1JYUA 2C9WA 1BM2A 4P9ZA 1Y57A 3GXWA 1O4GA 4NWGA 2EO6A 3IN7A 2CI8A 1I3ZA 2OZOA 2QMSA 2EYVA 4OHEA 3US4A 1AB2A 1O4BA 2MC1A 2EO3A 1O4MA 3KFJA 1X6CA 3BKBA 2HDVA 2DM0A 2EL8A 2MK2A 5DC0B 1BMBA 1QCFA 2B3OA 2HUWA 3MXCA 2LNWA 1A1EA 1CJ1A 4D8KA 3VRNA 3OB2B 3PFVA 3PLFB 5D0JA 1BHFA 1SPRA 2C0TA 1F1WA 2GE9A 4DGPA 2LQNA 1GHUA 3VS4A 3MXYA 1RJAA 4FL3A 1YVHA 4JE4A 1R1SA 4LUEA 2CR4A 4K2RA 1IS0A 1BF5A 1R1PA 4EIHA 5EHRA 1F2FA 1LUNA 3VS6A 2MQIA 4K11A 1PICA 1O45A 2AOAA 1OPLA 1FHSA 5CDWA 2SRCA 2EYZA 4OHHA 2RVFA 1D4WA 1O4HA 1A1AA 3VRZA 1SKJA 4M4ZA 4XZ1A 3HHMB 4LUDA 2ETZA 1A08A 2K79B 3N7YA 1LUIA 3WA4A 1TCEA 1LKKA 5HKWA 3BUOB 1AOUF 1O49A 2DCRA 3VROA 2H5KA 3VS7A 3VRRA 3M7FA 2AOBA 3QWYA 2IZVA 3EACA 2ABLA 1KC2A 4F5BA 2DX0A 1O4RA 2H8HA 3BUMB 1RQQC 3HCKA 1O4CA 2RSYA 1O43A 1BHHA 3HIZB 1D4TA 1OO3A 1SPSA 5GJIA 2Y1NA 1Z3KA 1KA6A 1AOTF 1O48A 1BFJA 1O44A 3IMJA 1Y1UA 3T04A 4P9VA 4OHLA 1OO4A 1LCJA 1CSYA 2PNBA 1TZEE 1X27A 2EYYA 2CI9A 2CRHA 3ZNIA 1FBVA 5DC4A 3PS5A 1LUKA 4A4CA 1JU5A 3VRYA 2PTKA 1O46A 3VS1A 2IUGA 2L6KA 1X0NA 4GL9E 3N8MA 1LCKA 3OVEA 1HCSB 1SHDA 1BG1A 1O4QA 1SHAA 1SHBA 1O4PA 3BUXB 2HCKA 1O4DA 1A1BA 1JYQA 2LNXA 1O4EA 2K7AB 2PLDA 2Y3AB 4H1OA 4JEGA 1XA6A 1O41A 4U1PA 1BKMA 4A4BA 1NZVA 3UYOA 2SHPA 1A81A 2OQ1A 3QWXX 2BBUA 3OB1B 3VRQA 5AULA 3OP0A 4E93A 1O4KA 4WWQA 2DLZA 2KK6A 2Y1MA 5HKYA 2EKXA 3CXLA 3S8OA 1O42A 1G83A 4H34A 1CWDL 2C0OA 4F5AA 3MAZA 2MRKA 4OHDA 2RORA 3GQIB 1OPKA 2C0IA 2EU0A 2FO0A 5DF6A 1QADA 2IUHA 3S8LA 5EHPA 2CBLA 3VGOA 2FCIA 1LKLA 2PLEA 4XZ0A 3S9KA 4K44A 1FMKA 3IMDA 4ROJA 1O4AA 3VS0A 1O4FA 3S8NA 4FBNA 4QSYA 3VS2A 4U17A 4X6SA 2MRJA 3PSJA 3EAZA 3CWGA 5EG3B 1O4LA 1A07A 2KNOA 3IN8A 2CIAA 1O4OA 4JGHA 1AYCA 1A1CA 3VRPA 2L4KA 4E68A 1O4IA 3VS5A 2RMXA 2YSXA 5EELA 5AXIA 3UF4A 5IBMA 1A09A 1CSZA 3PJPA 5DC9A 3CD3A 1NRVA 2DVJA 2PNAA 1D1ZA 1NZLA 1KA7A 1MW4A 2DLYA 3TL0A 1UUSA 1AYBA 1JYRA 5HKZA 5GJHA 2LCTA 4EY0A 1YVLA 1K9AA 5KAZA 4NWFA 3TKZA 2VIFA 5J3XA 1IJRA 3VS3A 4DGXA 1WQUA 3NHNA 3PQZA 3C7IA 4K45A 1O47A 1JWOA 2H46E 4L1BB 1O4NA 2AUGA 4GPLB 1RPYA 1GRIA 3PSKA 3OV1A 1AYAA 1HCTB 1FU5A
chains in the Genus database with same CATH superfamily
1QG1E 3N84A 5EEQA 2XP1A 5IBSA 3BUWB 3CBLA 1BKLA 2YU7A 2CS0A 2HDXA 1B47A 1MILA 2HMHA 2GSBA 4TZIA 1FYRA 1P13A 3K2MA 4F59A 4GWFA 1M27A 2ECDA 1CWEA 1FU6A 1H9OA 4OHIA 1BLJA 2LQWA 5BO4A 1LUMA 1R1QA 3GXXA 3BUNB 1KSWA 1BFIA 2IUIA 2EOBA 2L3TA 1AD5A 1BLKA 1BHHB 1ZFPE 1M61A 1O4JA 1FBZA 4FL2A 1UURA 2JYQA 1AYDA 5I6VA 1JYUA 2C9WA 1BM2A 4P9ZA 1Y57A 3GXWA 1O4GA 4NWGA 2EO6A 3IN7A 2CI8A 1I3ZA 2OZOA 2QMSA 2EYVA 4OHEA 3US4A 1AB2A 1O4BA 2MC1A 2EO3A 1O4MA 3KFJA 1X6CA 3BKBA 2HDVA 2DM0A 2EL8A 2MK2A 5DC0B 1BMBA 1QCFA 2B3OA 2HUWA 3MXCA 2LNWA 1A1EA 1CJ1A 4D8KA 3VRNA 3OB2B 3PFVA 3PLFB 1BHFA 5D0JA 1SPRA 2C0TA 1F1WA 2GE9A 4DGPA 2LQNA 1GHUA 3VS4A 3MXYA 1RJAA 4FL3A 1YVHA 4JE4A 1R1SA 4LUEA 2CR4A 4K2RA 1IS0A 1BF5A 1R1PA 4EIHA 5EHRA 1F2FA 1LUNA 3VS6A 2MQIA 4K11A 1PICA 1O45A 2AOAA 1OPLA 1FHSA 5CDWA 2SRCA 2EYZA 4OHHA 2RVFA 1D4WA 1O4HA 1A1AA 3VRZA 1SKJA 4M4ZA 4XZ1A 3HHMB 4LUDA 2ETZA 1A08A 2K79B 3N7YA 1LUIA 3WA4A 1TCEA 1LKKA 5HKWA 3BUOB 1AOUF 1O49A 2DCRA 3VROA 2H5KA 3VS7A 3VRRA 3M7FA 2AOBA 3QWYA 2IZVA 3EACA 2ABLA 1KC2A 4F5BA 2DX0A 1O4RA 2H8HA 3BUMB 3HCKA 1RQQC 1O4CA 2RSYA 1O43A 1BHHA 3HIZB 1D4TA 1OO3A 1SPSA 5GJIA 2Y1NA 1Z3KA 1KA6A 1AOTF 1O48A 1BFJA 1O44A 3IMJA 1Y1UA 3T04A 4P9VA 4OHLA 1OO4A 1LCJA 1CSYA 2PNBA 1TZEE 1X27A 2EYYA 2CI9A 2CRHA 3ZNIA 1FBVA 5DC4A 3PS5A 1LUKA 4A4CA 1JU5A 3VRYA 2PTKA 1O46A 3VS1A 2IUGA 2L6KA 1X0NA 4GL9E 3N8MA 1LCKA 3OVEA 1HCSB 1SHDA 1BG1A 1O4QA 1SHAA 1SHBA 1O4PA 3BUXB 2HCKA 1O4DA 1A1BA 1JYQA 2LNXA 1O4EA 2K7AB 2PLDA 2Y3AB 4H1OA 4JEGA 1XA6A 1O41A 4U1PA 1BKMA 4A4BA 1NZVA 3K2TA 3UYOA 2SHPA 1A81A 2OQ1A 3QWXX 2BBUA 3OB1B 3VRQA 5AULA 3OP0A 4E93A 1O4KA 4WWQA 2DLZA 2KK6A 2Y1MA 5HKYA 2EKXA 3CXLA 3S8OA 1O42A 1G83A 4H34A 1CWDL 2C0OA 4F5AA 3MAZA 2MRKA 4OHDA 2RORA 3GQIB 1OPKA 2C0IA 2EU0A 2FO0A 5DF6A 1QADA 2IUHA 3S8LA 5EHPA 2CBLA 3VGOA 2FCIA 1LKLA 2PLEA 4XZ0A 3S9KA 4K44A 1FMKA 3IMDA 4ROJA 1O4AA 3VS0A 3LYVA 1O4FA 3S8NA 4FBNA 4QSYA 3VS2A 4U17A 4X6SA 2MRJA 3PSJA 3EAZA 3CWGA 5EG3B 1O4LA 1A07A 2KNOA 3IN8A 2CIAA 1O4OA 4JGHA 1AYCA 1A1CA 2LRAA 3VRPA 2L4KA 4E68A 1O4IA 3VS5A 2RMXA 2YSXA 5EELA 5AXIA 3UF4A 5IBMA 1A09A 1CSZA 3PJPA 5DC9A 3CD3A 1NRVA 2DVJA 2PNAA 1D1ZA 1NZLA 1KA7A 1MW4A 2DLYA 3TL0A 1UUSA 1AYBA 1JYRA 5HKZA 5GJHA 2LCTA 4EY0A 1YVLA 1K9AA 5KAZA 4NWFA 3TKZA 2VIFA 5J3XA 1IJRA 3VS3A 4DGXA 1WQUA 3NHNA 3PQZA 3C7IA 4K45A 2KGYA 1O47A 1JWOA 2H46E 4L1BB 1O4NA 2AUGA 4GPLB 1RPYA 1GRIA 3PSKA 3OV1A 1AYAA 1HCTB 1FU5A
chains in the Genus database with same CATH topology
1QG1E 3N84A 5EEQA 2XP1A 5IBSA 3BUWB 3CBLA 1BKLA 2YU7A 2CS0A 2HDXA 1B47A 1MILA 2HMHA 2GSBA 4TZIA 1FYRA 1P13A 3K2MA 4F59A 4GWFA 1M27A 2ECDA 1CWEA 1FU6A 1H9OA 4OHIA 1BLJA 2LQWA 5BO4A 1LUMA 1R1QA 3GXXA 3BUNB 1KSWA 1BFIA 2IUIA 2EOBA 2L3TA 1AD5A 1BLKA 1BHHB 1ZFPE 1M61A 1O4JA 1FBZA 4FL2A 1UURA 2JYQA 1AYDA 5I6VA 1JYUA 2C9WA 1BM2A 4P9ZA 1Y57A 3GXWA 1O4GA 4NWGA 2EO6A 3IN7A 2CI8A 1I3ZA 2OZOA 2QMSA 2EYVA 4OHEA 3US4A 1AB2A 1O4BA 2MC1A 2EO3A 1O4MA 3KFJA 1X6CA 3BKBA 2HDVA 2DM0A 2EL8A 2MK2A 5DC0B 1BMBA 1QCFA 2B3OA 2HUWA 3MXCA 2LNWA 1A1EA 1CJ1A 4D8KA 3VRNA 3OB2B 3PFVA 3PLFB 5D0JA 1BHFA 1SPRA 2C0TA 1F1WA 2GE9A 4DGPA 2LQNA 1GHUA 3VS4A 3MXYA 1RJAA 4FL3A 1YVHA 4JE4A 1R1SA 4LUEA 2CR4A 4K2RA 1IS0A 1BF5A 1R1PA 4EIHA 5EHRA 1F2FA 1LUNA 3VS6A 2MQIA 4K11A 1PICA 1O45A 2AOAA 1OPLA 1FHSA 5CDWA 2SRCA 2EYZA 4OHHA 2RVFA 1D4WA 1O4HA 1A1AA 3VRZA 1SKJA 4M4ZA 4XZ1A 3HHMB 4LUDA 2ETZA 1A08A 2K79B 3N7YA 1LUIA 3WA4A 1TCEA 1LKKA 5HKWA 3BUOB 1AOUF 1O49A 2DCRA 3VROA 2H5KA 3VS7A 3VRRA 3M7FA 2AOBA 3QWYA 2IZVA 3EACA 2ABLA 1KC2A 4F5BA 2DX0A 1O4RA 2H8HA 3BUMB 1RQQC 3HCKA 1O4CA 2RSYA 1O43A 1BHHA 3HIZB 1D4TA 1OO3A 1SPSA 5GJIA 2Y1NA 1Z3KA 1KA6A 1AOTF 1O48A 1BFJA 1O44A 3IMJA 1Y1UA 3T04A 4P9VA 4OHLA 1OO4A 1LCJA 1CSYA 2PNBA 1TZEE 1X27A 2EYYA 2CI9A 2CRHA 3ZNIA 1FBVA 5DC4A 3PS5A 1LUKA 4A4CA 1JU5A 3VRYA 2PTKA 1O46A 3VS1A 2IUGA 2L6KA 1X0NA 4GL9E 3N8MA 1LCKA 3OVEA 1HCSB 1SHDA 1BG1A 1O4QA 1SHAA 1SHBA 1O4PA 3BUXB 2HCKA 1O4DA 1A1BA 1JYQA 2LNXA 1O4EA 2K7AB 2PLDA 2Y3AB 4H1OA 4JEGA 1XA6A 1O41A 4U1PA 1BKMA 4A4BA 1NZVA 3UYOA 2SHPA 1A81A 2OQ1A 3QWXX 2BBUA 3OB1B 3VRQA 5AULA 3OP0A 4E93A 1O4KA 4WWQA 2DLZA 2KK6A 2Y1MA 5HKYA 2EKXA 3CXLA 3S8OA 1O42A 1G83A 4H34A 1CWDL 2C0OA 4F5AA 3MAZA 2MRKA 4OHDA 2RORA 3GQIB 1OPKA 2C0IA 2EU0A 2FO0A 5DF6A 1QADA 2IUHA 3S8LA 5EHPA 2CBLA 3VGOA 2FCIA 1LKLA 2PLEA 4XZ0A 3S9KA 4K44A 1FMKA 3IMDA 4ROJA 1O4AA 3VS0A 1O4FA 3S8NA 4FBNA 4QSYA 3VS2A 4U17A 4X6SA 2MRJA 3PSJA 3EAZA 3CWGA 5EG3B 1O4LA 1A07A 2KNOA 3IN8A 2CIAA 1O4OA 4JGHA 1AYCA 1A1CA 3VRPA 2L4KA 4E68A 1O4IA 3VS5A 2RMXA 2YSXA 5EELA 5AXIA 3UF4A 5IBMA 1A09A 1CSZA 3PJPA 5DC9A 3CD3A 1NRVA 2DVJA 2PNAA 1D1ZA 1NZLA 1KA7A 1MW4A 2DLYA 3TL0A 1UUSA 1AYBA 1JYRA 5HKZA 5GJHA 2LCTA 4EY0A 1YVLA 1K9AA 5KAZA 4NWFA 3TKZA 2VIFA 5J3XA 1IJRA 3VS3A 4DGXA 1WQUA 3NHNA 3PQZA 3C7IA 4K45A 1O47A 1JWOA 2H46E 4L1BB 1O4NA 2AUGA 4GPLB 1RPYA 1GRIA 3PSKA 3OV1A 1AYAA 1HCTB 1FU5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QG1 E;  3N84 A;  5EEQ A;  2XP1 A;  5IBS A;  3BUW B;  3CBL A;  1BKL A;  2YU7 A;  2CS0 A;  2HDX A;  1B47 A;  1MIL A;  2HMH A;  2GSB A;  4TZI A;  1FYR A;  1P13 A;  3K2M A;  4F59 A;  4GWF A;  1M27 A;  2ECD A;  1CWE A;  1FU6 A;  1H9O A;  4OHI A;  1BLJ A;  2LQW A;  5BO4 A;  1LUM A;  1R1Q A;  3GXX A;  3BUN B;  1KSW A;  1BFI A;  2IUI A;  2EOB A;  2L3T A;  1AD5 A;  1BLK A;  1BHH B;  1ZFP E;  1M61 A;  1O4J A;  1FBZ A;  4FL2 A;  1UUR A;  2JYQ A;  1AYD A;  5I6V A;  1JYU A;  2C9W A;  1BM2 A;  4P9Z A;  1Y57 A;  3GXW A;  1O4G A;  4NWG A;  2EO6 A;  3IN7 A;  2CI8 A;  1I3Z A;  2OZO A;  2QMS A;  2EYV A;  4OHE A;  3US4 A;  1AB2 A;  1O4B A;  2MC1 A;  2EO3 A;  1O4M A;  3KFJ A;  1X6C A;  3BKB A;  2HDV A;  2DM0 A;  2EL8 A;  2MK2 A;  5DC0 B;  1BMB A;  1QCF A;  2B3O A;  2HUW A;  3MXC A;  2LNW A;  1A1E A;  1CJ1 A;  4D8K A;  3VRN A;  3OB2 B;  3PFV A;  3PLF B;  5D0J A;  1BHF A;  1SPR A;  2C0T A;  1F1W A;  2GE9 A;  4DGP A;  2LQN A;  1GHU A;  3VS4 A;  3MXY A;  1RJA A;  4FL3 A;  1YVH A;  4JE4 A;  1R1S A;  4LUE A;  2CR4 A;  4K2R A;  1IS0 A;  1BF5 A;  1R1P A;  4EIH A;  5EHR A;  1F2F A;  1LUN A;  3VS6 A;  2MQI A;  4K11 A;  1PIC A;  1O45 A;  2AOA A;  1OPL A;  1FHS A;  5CDW A;  2SRC A;  2EYZ A;  4OHH A;  2RVF A;  1D4W A;  1O4H A;  1A1A A;  3VRZ A;  1SKJ A;  4M4Z A;  4XZ1 A;  3HHM B;  4LUD A;  2ETZ A;  1A08 A;  2K79 B;  3N7Y A;  1LUI A;  3WA4 A;  1TCE A;  1LKK A;  5HKW A;  3BUO B;  1AOU F;  1O49 A;  2DCR A;  3VRO A;  2H5K A;  3VS7 A;  3VRR A;  3M7F A;  2AOB A;  3QWY A;  2IZV A;  3EAC A;  2ABL A;  1KC2 A;  4F5B A;  2DX0 A;  1O4R A;  2H8H A;  3BUM B;  1RQQ C;  3HCK A;  1O4C A;  2RSY A;  1O43 A;  1BHH A;  3HIZ B;  1D4T A;  1OO3 A;  1SPS A;  5GJI A;  2Y1N A;  1Z3K A;  1KA6 A;  1AOT F;  1O48 A;  1BFJ A;  1O44 A;  3IMJ A;  1Y1U A;  3T04 A;  4P9V A;  4OHL A;  1OO4 A;  1LCJ A;  1CSY A;  2PNB A;  1TZE E;  1X27 A;  2EYY A;  2CI9 A;  2CRH A;  3ZNI A;  1FBV A;  5DC4 A;  3PS5 A;  1LUK A;  4A4C A;  1JU5 A;  3VRY A;  2PTK A;  1O46 A;  3VS1 A;  2IUG A;  2L6K A;  1X0N A;  4GL9 E;  3N8M A;  1LCK A;  3OVE A;  1HCS B;  1SHD A;  1BG1 A;  1O4Q A;  1SHA A;  1SHB A;  1O4P A;  3BUX B;  2HCK A;  1O4D A;  1A1B A;  1JYQ A;  2LNX A;  1O4E A;  2K7A B;  2PLD A;  2Y3A B;  4H1O A;  4JEG A;  1XA6 A;  1O41 A;  4U1P A;  1BKM A;  4A4B A;  1NZV A;  3UYO A;  2SHP A;  1A81 A;  2OQ1 A;  3QWX X;  2BBU A;  3OB1 B;  3VRQ A;  5AUL A;  3OP0 A;  4E93 A;  1O4K A;  4WWQ A;  2DLZ A;  2KK6 A;  2Y1M A;  5HKY A;  2EKX A;  3CXL A;  3S8O A;  1O42 A;  1G83 A;  4H34 A;  1CWD L;  2C0O A;  4F5A A;  3MAZ A;  2MRK A;  4OHD A;  2ROR A;  3GQI B;  1OPK A;  2C0I A;  2EU0 A;  2FO0 A;  5DF6 A;  1QAD A;  2IUH A;  3S8L A;  5EHP A;  2CBL A;  3VGO A;  2FCI A;  1LKL A;  2PLE A;  4XZ0 A;  3S9K A;  4K44 A;  1FMK A;  3IMD A;  4ROJ A;  1O4A A;  3VS0 A;  1O4F A;  3S8N A;  4FBN A;  4QSY A;  3VS2 A;  4U17 A;  4X6S A;  2MRJ A;  3PSJ A;  3EAZ A;  3CWG A;  5EG3 B;  1O4L A;  1A07 A;  2KNO A;  3IN8 A;  2CIA A;  1O4O A;  4JGH A;  1AYC A;  1A1C A;  3VRP A;  2L4K A;  4E68 A;  1O4I A;  3VS5 A;  2RMX A;  2YSX A;  5EEL A;  5AXI A;  3UF4 A;  5IBM A;  1A09 A;  1CSZ A;  3PJP A;  5DC9 A;  3CD3 A;  1NRV A;  2DVJ A;  2PNA A;  1D1Z A;  1NZL A;  1KA7 A;  1MW4 A;  2DLY A;  3TL0 A;  1UUS A;  1AYB A;  1JYR A;  5HKZ A;  5GJH A;  2LCT A;  4EY0 A;  1YVL A;  1K9A A;  5KAZ A;  4NWF A;  3TKZ A;  2VIF A;  5J3X A;  1IJR A;  3VS3 A;  4DGX A;  1WQU A;  3NHN A;  3PQZ A;  3C7I A;  4K45 A;  1O47 A;  1JWO A;  2H46 E;  4L1B B;  1O4N A;  2AUG A;  4GPL B;  1RPY A;  1GRI A;  3PSK A;  3OV1 A;  1AYA A;  1HCT B;  1FU5 A; 
#chains in the Genus database with same CATH topology
 1QG1 E;  3N84 A;  5EEQ A;  2XP1 A;  5IBS A;  3BUW B;  3CBL A;  1BKL A;  2YU7 A;  2CS0 A;  2HDX A;  1B47 A;  1MIL A;  2HMH A;  2GSB A;  4TZI A;  1FYR A;  1P13 A;  3K2M A;  4F59 A;  4GWF A;  1M27 A;  2ECD A;  1CWE A;  1FU6 A;  1H9O A;  4OHI A;  1BLJ A;  2LQW A;  5BO4 A;  1LUM A;  1R1Q A;  3GXX A;  3BUN B;  1KSW A;  1BFI A;  2IUI A;  2EOB A;  2L3T A;  1AD5 A;  1BLK A;  1BHH B;  1ZFP E;  1M61 A;  1O4J A;  1FBZ A;  4FL2 A;  1UUR A;  2JYQ A;  1AYD A;  5I6V A;  1JYU A;  2C9W A;  1BM2 A;  4P9Z A;  1Y57 A;  3GXW A;  1O4G A;  4NWG A;  2EO6 A;  3IN7 A;  2CI8 A;  1I3Z A;  2OZO A;  2QMS A;  2EYV A;  4OHE A;  3US4 A;  1AB2 A;  1O4B A;  2MC1 A;  2EO3 A;  1O4M A;  3KFJ A;  1X6C A;  3BKB A;  2HDV A;  2DM0 A;  2EL8 A;  2MK2 A;  5DC0 B;  1BMB A;  1QCF A;  2B3O A;  2HUW A;  3MXC A;  2LNW A;  1A1E A;  1CJ1 A;  4D8K A;  3VRN A;  3OB2 B;  3PFV A;  3PLF B;  1BHF A;  5D0J A;  1SPR A;  2C0T A;  1F1W A;  2GE9 A;  4DGP A;  2LQN A;  1GHU A;  3VS4 A;  3MXY A;  1RJA A;  4FL3 A;  1YVH A;  4JE4 A;  1R1S A;  4LUE A;  2CR4 A;  4K2R A;  1IS0 A;  1BF5 A;  1R1P A;  4EIH A;  5EHR A;  1F2F A;  1LUN A;  3VS6 A;  2MQI A;  4K11 A;  1PIC A;  1O45 A;  2AOA A;  1OPL A;  1FHS A;  5CDW A;  2SRC A;  2EYZ A;  4OHH A;  2RVF A;  1D4W A;  1O4H A;  1A1A A;  3VRZ A;  1SKJ A;  4M4Z A;  4XZ1 A;  3HHM B;  4LUD A;  2ETZ A;  1A08 A;  2K79 B;  3N7Y A;  1LUI A;  3WA4 A;  1TCE A;  1LKK A;  5HKW A;  3BUO B;  1AOU F;  1O49 A;  2DCR A;  3VRO A;  2H5K A;  3VS7 A;  3VRR A;  3M7F A;  2AOB A;  3QWY A;  2IZV A;  3EAC A;  2ABL A;  1KC2 A;  4F5B A;  2DX0 A;  1O4R A;  2H8H A;  3BUM B;  3HCK A;  1RQQ C;  1O4C A;  2RSY A;  1O43 A;  1BHH A;  3HIZ B;  1D4T A;  1OO3 A;  1SPS A;  5GJI A;  2Y1N A;  1Z3K A;  1KA6 A;  1AOT F;  1O48 A;  1BFJ A;  1O44 A;  3IMJ A;  1Y1U A;  3T04 A;  4P9V A;  4OHL A;  1OO4 A;  1LCJ A;  1CSY A;  2PNB A;  1TZE E;  1X27 A;  2EYY A;  2CI9 A;  2CRH A;  3ZNI A;  1FBV A;  5DC4 A;  3PS5 A;  1LUK A;  4A4C A;  1JU5 A;  3VRY A;  2PTK A;  1O46 A;  3VS1 A;  2IUG A;  2L6K A;  1X0N A;  4GL9 E;  3N8M A;  1LCK A;  3OVE A;  1HCS B;  1SHD A;  1BG1 A;  1O4Q A;  1SHA A;  1SHB A;  1O4P A;  3BUX B;  2HCK A;  1O4D A;  1A1B A;  1JYQ A;  2LNX A;  1O4E A;  2K7A B;  2PLD A;  2Y3A B;  4H1O A;  4JEG A;  1XA6 A;  1O41 A;  4U1P A;  1BKM A;  4A4B A;  1NZV A;  3K2T A;  3UYO A;  2SHP A;  1A81 A;  2OQ1 A;  3QWX X;  2BBU A;  3OB1 B;  3VRQ A;  5AUL A;  3OP0 A;  4E93 A;  1O4K A;  4WWQ A;  2DLZ A;  2KK6 A;  2Y1M A;  5HKY A;  2EKX A;  3CXL A;  3S8O A;  1O42 A;  1G83 A;  4H34 A;  1CWD L;  2C0O A;  4F5A A;  3MAZ A;  2MRK A;  4OHD A;  2ROR A;  3GQI B;  1OPK A;  2C0I A;  2EU0 A;  2FO0 A;  5DF6 A;  1QAD A;  2IUH A;  3S8L A;  5EHP A;  2CBL A;  3VGO A;  2FCI A;  1LKL A;  2PLE A;  4XZ0 A;  3S9K A;  4K44 A;  1FMK A;  3IMD A;  4ROJ A;  1O4A A;  3VS0 A;  3LYV A;  1O4F A;  3S8N A;  4FBN A;  4QSY A;  3VS2 A;  4U17 A;  4X6S A;  2MRJ A;  3PSJ A;  3EAZ A;  3CWG A;  5EG3 B;  1O4L A;  1A07 A;  2KNO A;  3IN8 A;  2CIA A;  1O4O A;  4JGH A;  1AYC A;  1A1C A;  2LRA A;  3VRP A;  2L4K A;  4E68 A;  1O4I A;  3VS5 A;  2RMX A;  2YSX A;  5EEL A;  5AXI A;  3UF4 A;  5IBM A;  1A09 A;  1CSZ A;  3PJP A;  5DC9 A;  3CD3 A;  1NRV A;  2DVJ A;  2PNA A;  1D1Z A;  1NZL A;  1KA7 A;  1MW4 A;  2DLY A;  3TL0 A;  1UUS A;  1AYB A;  1JYR A;  5HKZ A;  5GJH A;  2LCT A;  4EY0 A;  1YVL A;  1K9A A;  5KAZ A;  4NWF A;  3TKZ A;  2VIF A;  5J3X A;  1IJR A;  3VS3 A;  4DGX A;  1WQU A;  3NHN A;  3PQZ A;  3C7I A;  4K45 A;  2KGY A;  1O47 A;  1JWO A;  2H46 E;  4L1B B;  1O4N A;  2AUG A;  4GPL B;  1RPY A;  1GRI A;  3PSK A;  3OV1 A;  1AYA A;  1HCT B;  1FU5 A; 
#chains in the Genus database with same CATH homology
 1QG1 E;  3N84 A;  5EEQ A;  2XP1 A;  5IBS A;  3BUW B;  3CBL A;  1BKL A;  2YU7 A;  2CS0 A;  2HDX A;  1B47 A;  1MIL A;  2HMH A;  2GSB A;  4TZI A;  1FYR A;  1P13 A;  3K2M A;  4F59 A;  4GWF A;  1M27 A;  2ECD A;  1CWE A;  1FU6 A;  1H9O A;  4OHI A;  1BLJ A;  2LQW A;  5BO4 A;  1LUM A;  1R1Q A;  3GXX A;  3BUN B;  1KSW A;  1BFI A;  2IUI A;  2EOB A;  2L3T A;  1AD5 A;  1BLK A;  1BHH B;  1ZFP E;  1M61 A;  1O4J A;  1FBZ A;  4FL2 A;  1UUR A;  2JYQ A;  1AYD A;  5I6V A;  1JYU A;  2C9W A;  1BM2 A;  4P9Z A;  1Y57 A;  3GXW A;  1O4G A;  4NWG A;  2EO6 A;  3IN7 A;  2CI8 A;  1I3Z A;  2OZO A;  2QMS A;  2EYV A;  4OHE A;  3US4 A;  1AB2 A;  1O4B A;  2MC1 A;  2EO3 A;  1O4M A;  3KFJ A;  1X6C A;  3BKB A;  2HDV A;  2DM0 A;  2EL8 A;  2MK2 A;  5DC0 B;  1BMB A;  1QCF A;  2B3O A;  2HUW A;  3MXC A;  2LNW A;  1A1E A;  1CJ1 A;  4D8K A;  3VRN A;  3OB2 B;  3PFV A;  3PLF B;  5D0J A;  1BHF A;  1SPR A;  2C0T A;  1F1W A;  2GE9 A;  4DGP A;  2LQN A;  1GHU A;  3VS4 A;  3MXY A;  1RJA A;  4FL3 A;  1YVH A;  4JE4 A;  1R1S A;  4LUE A;  2CR4 A;  4K2R A;  1IS0 A;  1BF5 A;  1R1P A;  4EIH A;  5EHR A;  1F2F A;  1LUN A;  3VS6 A;  2MQI A;  4K11 A;  1PIC A;  1O45 A;  2AOA A;  1OPL A;  1FHS A;  5CDW A;  2SRC A;  2EYZ A;  4OHH A;  2RVF A;  1D4W A;  1O4H A;  1A1A A;  3VRZ A;  1SKJ A;  4M4Z A;  4XZ1 A;  3HHM B;  4LUD A;  2ETZ A;  1A08 A;  2K79 B;  3N7Y A;  1LUI A;  3WA4 A;  1TCE A;  1LKK A;  5HKW A;  3BUO B;  1AOU F;  1O49 A;  2DCR A;  3VRO A;  2H5K A;  3VS7 A;  3VRR A;  3M7F A;  2AOB A;  3QWY A;  2IZV A;  3EAC A;  2ABL A;  1KC2 A;  4F5B A;  2DX0 A;  1O4R A;  2H8H A;  3BUM B;  1RQQ C;  3HCK A;  1O4C A;  2RSY A;  1O43 A;  1BHH A;  3HIZ B;  1D4T A;  1OO3 A;  1SPS A;  5GJI A;  2Y1N A;  1Z3K A;  1KA6 A;  1AOT F;  1O48 A;  1BFJ A;  1O44 A;  3IMJ A;  1Y1U A;  3T04 A;  4P9V A;  4OHL A;  1OO4 A;  1LCJ A;  1CSY A;  2PNB A;  1TZE E;  1X27 A;  2EYY A;  2CI9 A;  2CRH A;  3ZNI A;  1FBV A;  5DC4 A;  3PS5 A;  1LUK A;  4A4C A;  1JU5 A;  3VRY A;  2PTK A;  1O46 A;  3VS1 A;  2IUG A;  2L6K A;  1X0N A;  4GL9 E;  3N8M A;  1LCK A;  3OVE A;  1HCS B;  1SHD A;  1BG1 A;  1O4Q A;  1SHA A;  1SHB A;  1O4P A;  3BUX B;  2HCK A;  1O4D A;  1A1B A;  1JYQ A;  2LNX A;  1O4E A;  2K7A B;  2PLD A;  2Y3A B;  4H1O A;  4JEG A;  1XA6 A;  1O41 A;  4U1P A;  1BKM A;  4A4B A;  1NZV A;  3UYO A;  2SHP A;  1A81 A;  2OQ1 A;  3QWX X;  2BBU A;  3OB1 B;  3VRQ A;  5AUL A;  3OP0 A;  4E93 A;  1O4K A;  4WWQ A;  2DLZ A;  2KK6 A;  2Y1M A;  5HKY A;  2EKX A;  3CXL A;  3S8O A;  1O42 A;  1G83 A;  4H34 A;  1CWD L;  2C0O A;  4F5A A;  3MAZ A;  2MRK A;  4OHD A;  2ROR A;  3GQI B;  1OPK A;  2C0I A;  2EU0 A;  2FO0 A;  5DF6 A;  1QAD A;  2IUH A;  3S8L A;  5EHP A;  2CBL A;  3VGO A;  2FCI A;  1LKL A;  2PLE A;  4XZ0 A;  3S9K A;  4K44 A;  1FMK A;  3IMD A;  4ROJ A;  1O4A A;  3VS0 A;  1O4F A;  3S8N A;  4FBN A;  4QSY A;  3VS2 A;  4U17 A;  4X6S A;  2MRJ A;  3PSJ A;  3EAZ A;  3CWG A;  5EG3 B;  1O4L A;  1A07 A;  2KNO A;  3IN8 A;  2CIA A;  1O4O A;  4JGH A;  1AYC A;  1A1C A;  3VRP A;  2L4K A;  4E68 A;  1O4I A;  3VS5 A;  2RMX A;  2YSX A;  5EEL A;  5AXI A;  3UF4 A;  5IBM A;  1A09 A;  1CSZ A;  3PJP A;  5DC9 A;  3CD3 A;  1NRV A;  2DVJ A;  2PNA A;  1D1Z A;  1NZL A;  1KA7 A;  1MW4 A;  2DLY A;  3TL0 A;  1UUS A;  1AYB A;  1JYR A;  5HKZ A;  5GJH A;  2LCT A;  4EY0 A;  1YVL A;  1K9A A;  5KAZ A;  4NWF A;  3TKZ A;  2VIF A;  5J3X A;  1IJR A;  3VS3 A;  4DGX A;  1WQU A;  3NHN A;  3PQZ A;  3C7I A;  4K45 A;  1O47 A;  1JWO A;  2H46 E;  4L1B B;  1O4N A;  2AUG A;  4GPL B;  1RPY A;  1GRI A;  3PSK A;  3OV1 A;  1AYA A;  1HCT B;  1FU5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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