1O4DA

Crystal structure of sh2 in complex with ru78262.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4dA00
4NWGA 1LCKA 3VRNA 2MRJA 3EAZA 2MQIA 1O4RA 4P9ZA 1JYQA 5CDWA 1MW4A 2SHPA 4K44A 5GJHA 2GE9A 3OB1B 2EOBA 1FBVA 2HDXA 4GWFA 2C0OA 1X27A 2MRKA 4E93A 3CBLA 2KK6A 2ECDA 5I6VA 2LNWA 1OPLA 1NZLA 2EKXA 1LCJA 1SHBA 2Y3AB 1O48A 2LNXA 2YU7A 1BKLA 3VS0A 2RSYA 2Y1NA 3S9KA 3HIZB 1NRVA 3UF4A 1KC2A 2ETZA 4JE4A 3S8OA 1O4PA 5DC4A 2IZVA 3HCKA 5HKWA 3HHMB 1JYUA 1ZFPE 1BHHB 4P9VA 1AOTF 1QCFA 5DC9A 3BUXB 4U17A 1K9AA 3BUMB 1AB2A 1O4HA 1YVHA 3PFVA 3EACA 1BKMA 2XP1A 2EYVA 1O45A 1A1AA 3OV1A 1O46A 1CJ1A 3VRPA 2OQ1A 1O4MA 1AYAA 1XA6A 2EYZA 3C7IA 3GXWA 2C9WA 1I3ZA 2AUGA 1B47A 1KSWA 2PLDA 1BHHA 1IJRA 2PNAA 4NWFA 1O4JA 2CS0A 2IUIA 3MXYA 3CD3A 1CSYA 2DX0A 1AYCA 2H5KA 3N84A 1LUIA 2LQWA 3S8LA 2Y1MA 3IN8A 2IUHA 5D0JA 1Y57A 3MAZA 3VS6A 1RJAA 2PNBA 1YVLA 3TL0A 2EL8A 4LUDA 4DGXA 2AOBA 1CWEA 1BFJA 5EELA 4L1BB 1UURA 1A1CA 3VS7A 1O4CA 2LQNA 4OHIA 5KAZA 1AYDA 4XZ0A 2OZOA 2CRHA 2DVJA 1AYBA 5IBSA 4K11A 4F5AA 1O4OA 2EO3A 4TZIA 1SKJA 5DC0B 5AXIA 2L6KA 1TZEE 3PSKA 4D8KA 1O43A 1H9OA 3MXCA 4X6SA 1SHDA 4FL2A 3PS5A 3BUWB 3OB2B 3PLFB 1O42A 1PICA 1O44A 2LCTA 1IS0A 2L3TA 1MILA 1A1EA 3VRQA 5EHPA 4A4BA 3VGOA 1BF5A 4U1PA 1A1BA 3BUOB 1O4AA 1A09A 1KA7A 1O4DA 2C0TA 1O49A 1O4IA 4EIHA 3IMJA 4F5BA 1JU5A 1FHSA 1SPRA 1CWDL 4OHLA 1O4EA 2K7AB 1LKLA 1O4FA 1LUNA 2EYYA 1O4KA 2K79B 3S8NA 1F2FA 1X0NA 4M4ZA 5GJIA 4DGPA 2EO6A 3GXXA 1BLKA 3VS1A 4QSYA 1Y1UA 1O4QA 1X6CA 1O4NA 1FBZA 2DLYA 5EHRA 1M27A 3WA4A 3QWXX 2MK2A 3CXLA 2CBLA 5EG3B 1R1QA 1F1WA 2ABLA 1HCTB 1P13A 1NZVA 3BUNB 3PSJA 3K2MA 1OPKA 1LUMA 4A4CA 2B3OA 2RORA 1BG1A 3PQZA 1O41A 4OHHA 2GSBA 1FMKA 1O4BA 2DCRA 1G83A 1RPYA 3VS2A 2IUGA 2RVFA 2CI9A 3KFJA 1SHAA 2FCIA 2PTKA 3NHNA 4WWQA 5HKYA 1SPSA 3PJPA 2L4KA 1AD5A 1WQUA 1O4LA 1FU5A 1QG1E 3VS4A 1R1PA 2HCKA 1BMBA 2CIAA 2AOAA 5IBMA 2DM0A 2BBUA 1GHUA 4F59A 4H34A 2QMSA 4FBNA 1OO4A 5EEQA 1JWOA 3VRYA 4ROJA 2C0IA 4FL3A 1BLJA 2CI8A 5J3XA 2EU0A 4GPLB 1A08A 1FU6A 2JYQA 4K45A 4JEGA 4E68A 1HCSB 5AULA 2CR4A 2HDVA 3TKZA 3BKBA 1GRIA 4OHDA 1BHFA 2SRCA 4OHEA 2HMHA 1OO3A 2HUWA 1FYRA 1KA6A 1JYRA 3OP0A 3VS5A 1RQQC 4EY0A 2VIFA 4H1OA 1D1ZA 5HKZA 1AOUF 4K2RA 2FO0A 1BM2A 3OVEA 3VRZA 3N8MA 1UUSA 3N7YA 5DF6A 3US4A 4LUEA 2PLEA 3T04A 4GL9E 1LKKA 2DLZA 2YSXA 2MC1A 1O47A 1O4GA 3IN7A 3VROA 1LUKA 3UYOA 1D4WA 3M7FA 3ZNIA 1Z3KA 3VRRA 1QADA 2H8HA 1CSZA 1A81A 2KNOA 2RMXA 1A07A 1D4TA 4XZ1A 3QWYA 1BFIA 5BO4A 4JGHA 3VS3A 1M61A 1TCEA 3CWGA 1R1SA 3GQIB 2H46E 3IMDA
chains in the Genus database with same CATH superfamily
4NWGA 1LCKA 3VRNA 2MRJA 3EAZA 2MQIA 1O4RA 4P9ZA 1JYQA 5CDWA 1MW4A 2SHPA 4K44A 5GJHA 2GE9A 3OB1B 2EOBA 1FBVA 2HDXA 4GWFA 2C0OA 1X27A 2MRKA 4E93A 3CBLA 2KK6A 2ECDA 5I6VA 2LNWA 1OPLA 1NZLA 2EKXA 1LCJA 1SHBA 2Y3AB 1O48A 2LNXA 2YU7A 1BKLA 3VS0A 2RSYA 2Y1NA 3S9KA 3HIZB 1NRVA 3UF4A 1KC2A 2ETZA 4JE4A 3S8OA 1O4PA 5DC4A 2IZVA 3HCKA 5HKWA 3HHMB 1JYUA 1ZFPE 1BHHB 4P9VA 1AOTF 1QCFA 5DC9A 3BUXB 4U17A 1K9AA 3BUMB 1AB2A 1O4HA 1YVHA 3PFVA 3EACA 1BKMA 2XP1A 2EYVA 1O45A 1A1AA 3OV1A 1O46A 1CJ1A 3VRPA 2OQ1A 1O4MA 1AYAA 1XA6A 2EYZA 3C7IA 3GXWA 2C9WA 1I3ZA 2AUGA 1B47A 1KSWA 2PLDA 1BHHA 1IJRA 2PNAA 4NWFA 1O4JA 2CS0A 2IUIA 3MXYA 3CD3A 1CSYA 2DX0A 1AYCA 2H5KA 3N84A 1LUIA 2LQWA 3S8LA 2Y1MA 3IN8A 2IUHA 5D0JA 1Y57A 3MAZA 3VS6A 1RJAA 2PNBA 1YVLA 3TL0A 2EL8A 4LUDA 4DGXA 2AOBA 1CWEA 1BFJA 5EELA 4L1BB 2LRAA 1UURA 1A1CA 3VS7A 1O4CA 2LQNA 4OHIA 5KAZA 1AYDA 4XZ0A 2OZOA 2CRHA 2DVJA 1AYBA 5IBSA 4K11A 4F5AA 1O4OA 2EO3A 4TZIA 1SKJA 5DC0B 5AXIA 2L6KA 1TZEE 3PSKA 4D8KA 1O43A 1H9OA 3MXCA 4X6SA 1SHDA 4FL2A 3PS5A 3BUWB 3OB2B 3PLFB 1O42A 1PICA 1O44A 2LCTA 1IS0A 2L3TA 1MILA 1A1EA 3VRQA 5EHPA 4A4BA 3VGOA 1BF5A 4U1PA 1A1BA 3BUOB 1O4AA 1A09A 1KA7A 1O4DA 2C0TA 1O49A 1O4IA 4EIHA 3IMJA 4F5BA 1JU5A 1FHSA 1SPRA 1CWDL 4OHLA 1O4EA 2K7AB 1LKLA 1O4FA 1LUNA 2EYYA 1O4KA 2K79B 3S8NA 1F2FA 1X0NA 4M4ZA 5GJIA 4DGPA 2EO6A 3GXXA 1BLKA 3VS1A 4QSYA 1Y1UA 1O4QA 1X6CA 1O4NA 1FBZA 2DLYA 5EHRA 1M27A 3WA4A 3QWXX 2MK2A 3CXLA 2CBLA 5EG3B 1R1QA 1F1WA 2ABLA 1HCTB 1P13A 1NZVA 3BUNB 3PSJA 3K2MA 1OPKA 1LUMA 4A4CA 2B3OA 2RORA 1BG1A 3PQZA 1O41A 4OHHA 2GSBA 1FMKA 1O4BA 2DCRA 1G83A 1RPYA 3VS2A 2IUGA 2RVFA 2CI9A 3KFJA 1SHAA 2FCIA 2PTKA 3NHNA 4WWQA 5HKYA 1SPSA 3PJPA 2L4KA 1AD5A 1WQUA 1O4LA 1FU5A 1QG1E 3VS4A 1R1PA 2HCKA 1BMBA 2CIAA 2AOAA 5IBMA 2DM0A 2BBUA 1GHUA 4F59A 4H34A 2QMSA 4FBNA 1OO4A 5EEQA 1JWOA 3VRYA 4ROJA 2C0IA 4FL3A 1BLJA 2CI8A 5J3XA 3LYVA 2EU0A 4GPLB 1A08A 1FU6A 2JYQA 4K45A 4JEGA 4E68A 1HCSB 5AULA 2CR4A 2HDVA 3TKZA 3BKBA 1GRIA 4OHDA 1BHFA 2SRCA 4OHEA 2HMHA 1OO3A 2HUWA 1FYRA 1KA6A 1JYRA 3OP0A 3VS5A 1RQQC 4EY0A 2VIFA 4H1OA 1D1ZA 5HKZA 1AOUF 4K2RA 2FO0A 1BM2A 3OVEA 3VRZA 3N8MA 1UUSA 3N7YA 5DF6A 3US4A 4LUEA 2PLEA 3T04A 4GL9E 1LKKA 2DLZA 2YSXA 2MC1A 1O47A 1O4GA 3IN7A 3K2TA 3VROA 1LUKA 3UYOA 1D4WA 3M7FA 3ZNIA 1Z3KA 3VRRA 1QADA 2H8HA 1CSZA 1A81A 2KNOA 2RMXA 1A07A 1D4TA 4XZ1A 3QWYA 1BFIA 5BO4A 4JGHA 2KGYA 3VS3A 1M61A 1TCEA 3CWGA 1R1SA 3GQIB 2H46E 3IMDA
chains in the Genus database with same CATH topology
4NWGA 1LCKA 3VRNA 2MRJA 3EAZA 2MQIA 1O4RA 4P9ZA 1JYQA 5CDWA 1MW4A 2SHPA 4K44A 5GJHA 2GE9A 3OB1B 2EOBA 1FBVA 2HDXA 4GWFA 2C0OA 1X27A 2MRKA 4E93A 3CBLA 2KK6A 2ECDA 5I6VA 2LNWA 1OPLA 1NZLA 2EKXA 1LCJA 1SHBA 2Y3AB 1O48A 2LNXA 2YU7A 1BKLA 3VS0A 2RSYA 2Y1NA 3S9KA 3HIZB 1NRVA 3UF4A 1KC2A 2ETZA 4JE4A 3S8OA 1O4PA 5DC4A 2IZVA 3HCKA 5HKWA 3HHMB 1JYUA 1ZFPE 1BHHB 4P9VA 1AOTF 1QCFA 5DC9A 3BUXB 4U17A 1K9AA 3BUMB 1AB2A 1O4HA 1YVHA 3PFVA 3EACA 1BKMA 2XP1A 2EYVA 1O45A 1A1AA 3OV1A 1O46A 1CJ1A 3VRPA 2OQ1A 1O4MA 1AYAA 1XA6A 2EYZA 3C7IA 3GXWA 2C9WA 1I3ZA 2AUGA 1B47A 1KSWA 2PLDA 1BHHA 1IJRA 2PNAA 4NWFA 1O4JA 2CS0A 2IUIA 3MXYA 3CD3A 1CSYA 2DX0A 1AYCA 2H5KA 3N84A 1LUIA 2LQWA 3S8LA 2Y1MA 3IN8A 2IUHA 5D0JA 1Y57A 3MAZA 3VS6A 1RJAA 2PNBA 1YVLA 3TL0A 2EL8A 4LUDA 4DGXA 2AOBA 1CWEA 1BFJA 5EELA 4L1BB 1UURA 1A1CA 3VS7A 1O4CA 2LQNA 4OHIA 5KAZA 1AYDA 4XZ0A 2OZOA 2CRHA 2DVJA 1AYBA 5IBSA 4K11A 4F5AA 1O4OA 2EO3A 4TZIA 1SKJA 5DC0B 5AXIA 2L6KA 1TZEE 3PSKA 4D8KA 1O43A 1H9OA 3MXCA 4X6SA 1SHDA 4FL2A 3PS5A 3BUWB 3OB2B 3PLFB 1O42A 1PICA 1O44A 2LCTA 1IS0A 2L3TA 1MILA 1A1EA 3VRQA 5EHPA 4A4BA 3VGOA 1BF5A 4U1PA 1A1BA 3BUOB 1O4AA 1A09A 1KA7A 1O4DA 2C0TA 1O49A 1O4IA 4EIHA 3IMJA 4F5BA 1JU5A 1FHSA 1SPRA 1CWDL 4OHLA 1O4EA 2K7AB 1LKLA 1O4FA 1LUNA 2EYYA 1O4KA 2K79B 3S8NA 1F2FA 1X0NA 4M4ZA 5GJIA 4DGPA 2EO6A 3GXXA 1BLKA 3VS1A 4QSYA 1Y1UA 1O4QA 1X6CA 1O4NA 1FBZA 2DLYA 5EHRA 1M27A 3WA4A 3QWXX 2MK2A 3CXLA 2CBLA 5EG3B 1R1QA 1F1WA 2ABLA 1HCTB 1P13A 1NZVA 3BUNB 3PSJA 3K2MA 1OPKA 1LUMA 4A4CA 2B3OA 2RORA 1BG1A 3PQZA 1O41A 4OHHA 2GSBA 1FMKA 1O4BA 2DCRA 1G83A 1RPYA 3VS2A 2IUGA 2RVFA 2CI9A 3KFJA 1SHAA 2FCIA 2PTKA 3NHNA 4WWQA 5HKYA 1SPSA 3PJPA 2L4KA 1AD5A 1WQUA 1O4LA 1FU5A 1QG1E 3VS4A 1R1PA 2HCKA 1BMBA 2CIAA 2AOAA 5IBMA 2DM0A 2BBUA 1GHUA 4F59A 4H34A 2QMSA 4FBNA 1OO4A 5EEQA 1JWOA 3VRYA 4ROJA 2C0IA 4FL3A 1BLJA 2CI8A 5J3XA 2EU0A 4GPLB 1A08A 1FU6A 2JYQA 4K45A 4JEGA 4E68A 1HCSB 5AULA 2CR4A 2HDVA 3TKZA 3BKBA 1GRIA 4OHDA 1BHFA 2SRCA 4OHEA 2HMHA 1OO3A 2HUWA 1FYRA 1KA6A 1JYRA 3OP0A 3VS5A 1RQQC 4EY0A 2VIFA 4H1OA 1D1ZA 5HKZA 1AOUF 4K2RA 2FO0A 1BM2A 3OVEA 3VRZA 3N8MA 1UUSA 3N7YA 5DF6A 3US4A 4LUEA 2PLEA 3T04A 4GL9E 1LKKA 2DLZA 2YSXA 2MC1A 1O47A 1O4GA 3IN7A 3VROA 1LUKA 3UYOA 1D4WA 3M7FA 3ZNIA 1Z3KA 3VRRA 1QADA 2H8HA 1CSZA 1A81A 2KNOA 2RMXA 1A07A 1D4TA 4XZ1A 3QWYA 1BFIA 5BO4A 4JGHA 3VS3A 1M61A 1TCEA 3CWGA 1R1SA 3GQIB 2H46E 3IMDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NWG A;  1LCK A;  3VRN A;  2MRJ A;  3EAZ A;  2MQI A;  1O4R A;  4P9Z A;  1JYQ A;  5CDW A;  1MW4 A;  2SHP A;  4K44 A;  5GJH A;  2GE9 A;  3OB1 B;  2EOB A;  1FBV A;  2HDX A;  4GWF A;  2C0O A;  1X27 A;  2MRK A;  4E93 A;  3CBL A;  2KK6 A;  2ECD A;  5I6V A;  2LNW A;  1OPL A;  1NZL A;  2EKX A;  1LCJ A;  1SHB A;  2Y3A B;  1O48 A;  2LNX A;  2YU7 A;  1BKL A;  3VS0 A;  2RSY A;  2Y1N A;  3S9K A;  3HIZ B;  1NRV A;  3UF4 A;  1KC2 A;  2ETZ A;  4JE4 A;  3S8O A;  1O4P A;  5DC4 A;  2IZV A;  3HCK A;  5HKW A;  3HHM B;  1JYU A;  1ZFP E;  1BHH B;  4P9V A;  1AOT F;  1QCF A;  5DC9 A;  3BUX B;  4U17 A;  1K9A A;  3BUM B;  1AB2 A;  1O4H A;  1YVH A;  3PFV A;  3EAC A;  1BKM A;  2XP1 A;  2EYV A;  1O45 A;  1A1A A;  3OV1 A;  1O46 A;  1CJ1 A;  3VRP A;  2OQ1 A;  1O4M A;  1AYA A;  1XA6 A;  2EYZ A;  3C7I A;  3GXW A;  2C9W A;  1I3Z A;  2AUG A;  1B47 A;  1KSW A;  2PLD A;  1BHH A;  1IJR A;  2PNA A;  4NWF A;  1O4J A;  2CS0 A;  2IUI A;  3MXY A;  3CD3 A;  1CSY A;  2DX0 A;  1AYC A;  2H5K A;  3N84 A;  1LUI A;  2LQW A;  3S8L A;  2Y1M A;  3IN8 A;  2IUH A;  5D0J A;  1Y57 A;  3MAZ A;  3VS6 A;  1RJA A;  2PNB A;  1YVL A;  3TL0 A;  2EL8 A;  4LUD A;  4DGX A;  2AOB A;  1CWE A;  1BFJ A;  5EEL A;  4L1B B;  1UUR A;  1A1C A;  3VS7 A;  1O4C A;  2LQN A;  4OHI A;  5KAZ A;  1AYD A;  4XZ0 A;  2OZO A;  2CRH A;  2DVJ A;  1AYB A;  5IBS A;  4K11 A;  4F5A A;  1O4O A;  2EO3 A;  4TZI A;  1SKJ A;  5DC0 B;  5AXI A;  2L6K A;  1TZE E;  3PSK A;  4D8K A;  1O43 A;  1H9O A;  3MXC A;  4X6S A;  1SHD A;  4FL2 A;  3PS5 A;  3BUW B;  3OB2 B;  3PLF B;  1O42 A;  1PIC A;  1O44 A;  2LCT A;  1IS0 A;  2L3T A;  1MIL A;  1A1E A;  3VRQ A;  5EHP A;  4A4B A;  3VGO A;  1BF5 A;  4U1P A;  1A1B A;  3BUO B;  1O4A A;  1A09 A;  1KA7 A;  1O4D A;  2C0T A;  1O49 A;  1O4I A;  4EIH A;  3IMJ A;  4F5B A;  1JU5 A;  1FHS A;  1SPR A;  1CWD L;  4OHL A;  1O4E A;  2K7A B;  1LKL A;  1O4F A;  1LUN A;  2EYY A;  1O4K A;  2K79 B;  3S8N A;  1F2F A;  1X0N A;  4M4Z A;  5GJI A;  4DGP A;  2EO6 A;  3GXX A;  1BLK A;  3VS1 A;  4QSY A;  1Y1U A;  1O4Q A;  1X6C A;  1O4N A;  1FBZ A;  2DLY A;  5EHR A;  1M27 A;  3WA4 A;  3QWX X;  2MK2 A;  3CXL A;  2CBL A;  5EG3 B;  1R1Q A;  1F1W A;  2ABL A;  1HCT B;  1P13 A;  1NZV A;  3BUN B;  3PSJ A;  3K2M A;  1OPK A;  1LUM A;  4A4C A;  2B3O A;  2ROR A;  1BG1 A;  3PQZ A;  1O41 A;  4OHH A;  2GSB A;  1FMK A;  1O4B A;  2DCR A;  1G83 A;  1RPY A;  3VS2 A;  2IUG A;  2RVF A;  2CI9 A;  3KFJ A;  1SHA A;  2FCI A;  2PTK A;  3NHN A;  4WWQ A;  5HKY A;  1SPS A;  3PJP A;  2L4K A;  1AD5 A;  1WQU A;  1O4L A;  1FU5 A;  1QG1 E;  3VS4 A;  1R1P A;  2HCK A;  1BMB A;  2CIA A;  2AOA A;  5IBM A;  2DM0 A;  2BBU A;  1GHU A;  4F59 A;  4H34 A;  2QMS A;  4FBN A;  1OO4 A;  5EEQ A;  1JWO A;  3VRY A;  4ROJ A;  2C0I A;  4FL3 A;  1BLJ A;  2CI8 A;  5J3X A;  2EU0 A;  4GPL B;  1A08 A;  1FU6 A;  2JYQ A;  4K45 A;  4JEG A;  4E68 A;  1HCS B;  5AUL A;  2CR4 A;  2HDV A;  3TKZ A;  3BKB A;  1GRI A;  4OHD A;  1BHF A;  2SRC A;  4OHE A;  2HMH A;  1OO3 A;  2HUW A;  1FYR A;  1KA6 A;  1JYR A;  3OP0 A;  3VS5 A;  1RQQ C;  4EY0 A;  2VIF A;  4H1O A;  1D1Z A;  5HKZ A;  1AOU F;  4K2R A;  2FO0 A;  1BM2 A;  3OVE A;  3VRZ A;  3N8M A;  1UUS A;  3N7Y A;  5DF6 A;  3US4 A;  4LUE A;  2PLE A;  3T04 A;  4GL9 E;  1LKK A;  2DLZ A;  2YSX A;  2MC1 A;  1O47 A;  1O4G A;  3IN7 A;  3VRO A;  1LUK A;  3UYO A;  1D4W A;  3M7F A;  3ZNI A;  1Z3K A;  3VRR A;  1QAD A;  2H8H A;  1CSZ A;  1A81 A;  2KNO A;  2RMX A;  1A07 A;  1D4T A;  4XZ1 A;  3QWY A;  1BFI A;  5BO4 A;  4JGH A;  3VS3 A;  1M61 A;  1TCE A;  3CWG A;  1R1S A;  3GQI B;  2H46 E;  3IMD A; 
#chains in the Genus database with same CATH topology
 4NWG A;  1LCK A;  3VRN A;  2MRJ A;  3EAZ A;  2MQI A;  1O4R A;  4P9Z A;  1JYQ A;  5CDW A;  1MW4 A;  2SHP A;  4K44 A;  5GJH A;  2GE9 A;  3OB1 B;  2EOB A;  1FBV A;  2HDX A;  4GWF A;  2C0O A;  1X27 A;  2MRK A;  4E93 A;  3CBL A;  2KK6 A;  2ECD A;  5I6V A;  2LNW A;  1OPL A;  1NZL A;  2EKX A;  1LCJ A;  1SHB A;  2Y3A B;  1O48 A;  2LNX A;  2YU7 A;  1BKL A;  3VS0 A;  2RSY A;  2Y1N A;  3S9K A;  3HIZ B;  1NRV A;  3UF4 A;  1KC2 A;  2ETZ A;  4JE4 A;  3S8O A;  1O4P A;  5DC4 A;  2IZV A;  3HCK A;  5HKW A;  3HHM B;  1JYU A;  1ZFP E;  1BHH B;  4P9V A;  1AOT F;  1QCF A;  5DC9 A;  3BUX B;  4U17 A;  1K9A A;  3BUM B;  1AB2 A;  1O4H A;  1YVH A;  3PFV A;  3EAC A;  1BKM A;  2XP1 A;  2EYV A;  1O45 A;  1A1A A;  3OV1 A;  1O46 A;  1CJ1 A;  3VRP A;  2OQ1 A;  1O4M A;  1AYA A;  1XA6 A;  2EYZ A;  3C7I A;  3GXW A;  2C9W A;  1I3Z A;  2AUG A;  1B47 A;  1KSW A;  2PLD A;  1BHH A;  1IJR A;  2PNA A;  4NWF A;  1O4J A;  2CS0 A;  2IUI A;  3MXY A;  3CD3 A;  1CSY A;  2DX0 A;  1AYC A;  2H5K A;  3N84 A;  1LUI A;  2LQW A;  3S8L A;  2Y1M A;  3IN8 A;  2IUH A;  5D0J A;  1Y57 A;  3MAZ A;  3VS6 A;  1RJA A;  2PNB A;  1YVL A;  3TL0 A;  2EL8 A;  4LUD A;  4DGX A;  2AOB A;  1CWE A;  1BFJ A;  5EEL A;  4L1B B;  2LRA A;  1UUR A;  1A1C A;  3VS7 A;  1O4C A;  2LQN A;  4OHI A;  5KAZ A;  1AYD A;  4XZ0 A;  2OZO A;  2CRH A;  2DVJ A;  1AYB A;  5IBS A;  4K11 A;  4F5A A;  1O4O A;  2EO3 A;  4TZI A;  1SKJ A;  5DC0 B;  5AXI A;  2L6K A;  1TZE E;  3PSK A;  4D8K A;  1O43 A;  1H9O A;  3MXC A;  4X6S A;  1SHD A;  4FL2 A;  3PS5 A;  3BUW B;  3OB2 B;  3PLF B;  1O42 A;  1PIC A;  1O44 A;  2LCT A;  1IS0 A;  2L3T A;  1MIL A;  1A1E A;  3VRQ A;  5EHP A;  4A4B A;  3VGO A;  1BF5 A;  4U1P A;  1A1B A;  3BUO B;  1O4A A;  1A09 A;  1KA7 A;  1O4D A;  2C0T A;  1O49 A;  1O4I A;  4EIH A;  3IMJ A;  4F5B A;  1JU5 A;  1FHS A;  1SPR A;  1CWD L;  4OHL A;  1O4E A;  2K7A B;  1LKL A;  1O4F A;  1LUN A;  2EYY A;  1O4K A;  2K79 B;  3S8N A;  1F2F A;  1X0N A;  4M4Z A;  5GJI A;  4DGP A;  2EO6 A;  3GXX A;  1BLK A;  3VS1 A;  4QSY A;  1Y1U A;  1O4Q A;  1X6C A;  1O4N A;  1FBZ A;  2DLY A;  5EHR A;  1M27 A;  3WA4 A;  3QWX X;  2MK2 A;  3CXL A;  2CBL A;  5EG3 B;  1R1Q A;  1F1W A;  2ABL A;  1HCT B;  1P13 A;  1NZV A;  3BUN B;  3PSJ A;  3K2M A;  1OPK A;  1LUM A;  4A4C A;  2B3O A;  2ROR A;  1BG1 A;  3PQZ A;  1O41 A;  4OHH A;  2GSB A;  1FMK A;  1O4B A;  2DCR A;  1G83 A;  1RPY A;  3VS2 A;  2IUG A;  2RVF A;  2CI9 A;  3KFJ A;  1SHA A;  2FCI A;  2PTK A;  3NHN A;  4WWQ A;  5HKY A;  1SPS A;  3PJP A;  2L4K A;  1AD5 A;  1WQU A;  1O4L A;  1FU5 A;  1QG1 E;  3VS4 A;  1R1P A;  2HCK A;  1BMB A;  2CIA A;  2AOA A;  5IBM A;  2DM0 A;  2BBU A;  1GHU A;  4F59 A;  4H34 A;  2QMS A;  4FBN A;  1OO4 A;  5EEQ A;  1JWO A;  3VRY A;  4ROJ A;  2C0I A;  4FL3 A;  1BLJ A;  2CI8 A;  5J3X A;  3LYV A;  2EU0 A;  4GPL B;  1A08 A;  1FU6 A;  2JYQ A;  4K45 A;  4JEG A;  4E68 A;  1HCS B;  5AUL A;  2CR4 A;  2HDV A;  3TKZ A;  3BKB A;  1GRI A;  4OHD A;  1BHF A;  2SRC A;  4OHE A;  2HMH A;  1OO3 A;  2HUW A;  1FYR A;  1KA6 A;  1JYR A;  3OP0 A;  3VS5 A;  1RQQ C;  4EY0 A;  2VIF A;  4H1O A;  1D1Z A;  5HKZ A;  1AOU F;  4K2R A;  2FO0 A;  1BM2 A;  3OVE A;  3VRZ A;  3N8M A;  1UUS A;  3N7Y A;  5DF6 A;  3US4 A;  4LUE A;  2PLE A;  3T04 A;  4GL9 E;  1LKK A;  2DLZ A;  2YSX A;  2MC1 A;  1O47 A;  1O4G A;  3IN7 A;  3K2T A;  3VRO A;  1LUK A;  3UYO A;  1D4W A;  3M7F A;  3ZNI A;  1Z3K A;  3VRR A;  1QAD A;  2H8H A;  1CSZ A;  1A81 A;  2KNO A;  2RMX A;  1A07 A;  1D4T A;  4XZ1 A;  3QWY A;  1BFI A;  5BO4 A;  4JGH A;  2KGY A;  3VS3 A;  1M61 A;  1TCE A;  3CWG A;  1R1S A;  3GQI B;  2H46 E;  3IMD A; 
#chains in the Genus database with same CATH homology
 4NWG A;  1LCK A;  3VRN A;  2MRJ A;  3EAZ A;  2MQI A;  1O4R A;  4P9Z A;  1JYQ A;  5CDW A;  1MW4 A;  2SHP A;  4K44 A;  5GJH A;  2GE9 A;  3OB1 B;  2EOB A;  1FBV A;  2HDX A;  4GWF A;  2C0O A;  1X27 A;  2MRK A;  4E93 A;  3CBL A;  2KK6 A;  2ECD A;  5I6V A;  2LNW A;  1OPL A;  1NZL A;  2EKX A;  1LCJ A;  1SHB A;  2Y3A B;  1O48 A;  2LNX A;  2YU7 A;  1BKL A;  3VS0 A;  2RSY A;  2Y1N A;  3S9K A;  3HIZ B;  1NRV A;  3UF4 A;  1KC2 A;  2ETZ A;  4JE4 A;  3S8O A;  1O4P A;  5DC4 A;  2IZV A;  3HCK A;  5HKW A;  3HHM B;  1JYU A;  1ZFP E;  1BHH B;  4P9V A;  1AOT F;  1QCF A;  5DC9 A;  3BUX B;  4U17 A;  1K9A A;  3BUM B;  1AB2 A;  1O4H A;  1YVH A;  3PFV A;  3EAC A;  1BKM A;  2XP1 A;  2EYV A;  1O45 A;  1A1A A;  3OV1 A;  1O46 A;  1CJ1 A;  3VRP A;  2OQ1 A;  1O4M A;  1AYA A;  1XA6 A;  2EYZ A;  3C7I A;  3GXW A;  2C9W A;  1I3Z A;  2AUG A;  1B47 A;  1KSW A;  2PLD A;  1BHH A;  1IJR A;  2PNA A;  4NWF A;  1O4J A;  2CS0 A;  2IUI A;  3MXY A;  3CD3 A;  1CSY A;  2DX0 A;  1AYC A;  2H5K A;  3N84 A;  1LUI A;  2LQW A;  3S8L A;  2Y1M A;  3IN8 A;  2IUH A;  5D0J A;  1Y57 A;  3MAZ A;  3VS6 A;  1RJA A;  2PNB A;  1YVL A;  3TL0 A;  2EL8 A;  4LUD A;  4DGX A;  2AOB A;  1CWE A;  1BFJ A;  5EEL A;  4L1B B;  1UUR A;  1A1C A;  3VS7 A;  1O4C A;  2LQN A;  4OHI A;  5KAZ A;  1AYD A;  4XZ0 A;  2OZO A;  2CRH A;  2DVJ A;  1AYB A;  5IBS A;  4K11 A;  4F5A A;  1O4O A;  2EO3 A;  4TZI A;  1SKJ A;  5DC0 B;  5AXI A;  2L6K A;  1TZE E;  3PSK A;  4D8K A;  1O43 A;  1H9O A;  3MXC A;  4X6S A;  1SHD A;  4FL2 A;  3PS5 A;  3BUW B;  3OB2 B;  3PLF B;  1O42 A;  1PIC A;  1O44 A;  2LCT A;  1IS0 A;  2L3T A;  1MIL A;  1A1E A;  3VRQ A;  5EHP A;  4A4B A;  3VGO A;  1BF5 A;  4U1P A;  1A1B A;  3BUO B;  1O4A A;  1A09 A;  1KA7 A;  1O4D A;  2C0T A;  1O49 A;  1O4I A;  4EIH A;  3IMJ A;  4F5B A;  1JU5 A;  1FHS A;  1SPR A;  1CWD L;  4OHL A;  1O4E A;  2K7A B;  1LKL A;  1O4F A;  1LUN A;  2EYY A;  1O4K A;  2K79 B;  3S8N A;  1F2F A;  1X0N A;  4M4Z A;  5GJI A;  4DGP A;  2EO6 A;  3GXX A;  1BLK A;  3VS1 A;  4QSY A;  1Y1U A;  1O4Q A;  1X6C A;  1O4N A;  1FBZ A;  2DLY A;  5EHR A;  1M27 A;  3WA4 A;  3QWX X;  2MK2 A;  3CXL A;  2CBL A;  5EG3 B;  1R1Q A;  1F1W A;  2ABL A;  1HCT B;  1P13 A;  1NZV A;  3BUN B;  3PSJ A;  3K2M A;  1OPK A;  1LUM A;  4A4C A;  2B3O A;  2ROR A;  1BG1 A;  3PQZ A;  1O41 A;  4OHH A;  2GSB A;  1FMK A;  1O4B A;  2DCR A;  1G83 A;  1RPY A;  3VS2 A;  2IUG A;  2RVF A;  2CI9 A;  3KFJ A;  1SHA A;  2FCI A;  2PTK A;  3NHN A;  4WWQ A;  5HKY A;  1SPS A;  3PJP A;  2L4K A;  1AD5 A;  1WQU A;  1O4L A;  1FU5 A;  1QG1 E;  3VS4 A;  1R1P A;  2HCK A;  1BMB A;  2CIA A;  2AOA A;  5IBM A;  2DM0 A;  2BBU A;  1GHU A;  4F59 A;  4H34 A;  2QMS A;  4FBN A;  1OO4 A;  5EEQ A;  1JWO A;  3VRY A;  4ROJ A;  2C0I A;  4FL3 A;  1BLJ A;  2CI8 A;  5J3X A;  2EU0 A;  4GPL B;  1A08 A;  1FU6 A;  2JYQ A;  4K45 A;  4JEG A;  4E68 A;  1HCS B;  5AUL A;  2CR4 A;  2HDV A;  3TKZ A;  3BKB A;  1GRI A;  4OHD A;  1BHF A;  2SRC A;  4OHE A;  2HMH A;  1OO3 A;  2HUW A;  1FYR A;  1KA6 A;  1JYR A;  3OP0 A;  3VS5 A;  1RQQ C;  4EY0 A;  2VIF A;  4H1O A;  1D1Z A;  5HKZ A;  1AOU F;  4K2R A;  2FO0 A;  1BM2 A;  3OVE A;  3VRZ A;  3N8M A;  1UUS A;  3N7Y A;  5DF6 A;  3US4 A;  4LUE A;  2PLE A;  3T04 A;  4GL9 E;  1LKK A;  2DLZ A;  2YSX A;  2MC1 A;  1O47 A;  1O4G A;  3IN7 A;  3VRO A;  1LUK A;  3UYO A;  1D4W A;  3M7F A;  3ZNI A;  1Z3K A;  3VRR A;  1QAD A;  2H8H A;  1CSZ A;  1A81 A;  2KNO A;  2RMX A;  1A07 A;  1D4T A;  4XZ1 A;  3QWY A;  1BFI A;  5BO4 A;  4JGH A;  3VS3 A;  1M61 A;  1TCE A;  3CWG A;  1R1S A;  3GQI B;  2H46 E;  3IMD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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