1O46A

Crystal structure of sh2 in complex with ru90395.
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 25
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o46A00
3OP0A 1SHBA 2EU0A 3TKZA 3HCKA 4NWGA 1OO3A 5HKWA 4QSYA 5GJHA 1JU5A 3VGOA 2B3OA 3US4A 3VRNA 2DLYA 2MQIA 1O4NA 2KK6A 2CBLA 1O46A 1O43A 1CWEA 4H1OA 2HCKA 1MW4A 5EHRA 2SRCA 1AB2A 1QCFA 1WQUA 1O4BA 1O49A 1X27A 3VS2A 4F59A 5D0JA 4JGHA 3BKBA 3VS1A 2EYVA 3CXLA 2RMXA 5HKZA 5BO4A 2DVJA 5EEQA 1IJRA 3UYOA 1BHFA 2IZVA 2ECDA 2AUGA 3IMDA 4FL2A 5AXIA 4ROJA 4OHDA 1UURA 1TCEA 2FCIA 1LUIA 1Y57A 2PLDA 2CS0A 3HHMB 2SHPA 2LNXA 1AYAA 4P9ZA 1O4QA 4A4BA 1CSZA 5DC0B 1AYBA 2LNWA 3PQZA 5HKYA 5KAZA 1O4IA 1O4KA 1SHDA 3VRRA 3UF4A 1QADA 2GE9A 1BM2A 2AOAA 1FU6A 1M27A 2Y1MA 3PLFB 1GHUA 2IUIA 3BUMB 1SKJA 1NZLA 1BLJA 4K45A 1ZFPE 2DLZA 5DF6A 4K2RA 3S8OA 1KA7A 2LQWA 4GWFA 1O4FA 2EYZA 5J3XA 1O4HA 2H46E 1BMBA 3OB2B 1A81A 2K79B 2RVFA 1D4TA 1LKLA 4XZ0A 2GSBA 1AYDA 2Y1NA 3GQIB 5IBSA 1HCSB 1LCKA 1BHHB 2QMSA 1O4LA 2CI9A 1OO4A 1OPLA 3VS7A 1BKLA 2EKXA 3VRQA 3EAZA 1UUSA 4E68A 3C7IA 2EO3A 2K7AB 2OQ1A 3PSKA 1HCTB 4OHHA 3VS4A 4A4CA 1A07A 1O4CA 1X0NA 4H34A 1O48A 1RPYA 4JE4A 3EACA 2C0IA 2MRKA 4TZIA 3OV1A 1P13A 1O4PA 3OB1B 5GJIA 3PFVA 3VS6A 4EY0A 3CBLA 3KFJA 2RORA 3WA4A 4DGPA 3VS0A 1BHHA 3BUXB 3CWGA 2VIFA 4X6SA 1D1ZA 2BBUA 3CD3A 2HMHA 5IBMA 3VS5A 1BKMA 1QG1E 2CI8A 2IUHA 2EOBA 1O4AA 1MILA 4E93A 5DC4A 1FHSA 3T04A 3S8LA 1M61A 3BUNB 2DCRA 1LUKA 1CSYA 3VRYA 4OHIA 1BG1A 4WWQA 1F2FA 2PNAA 3PJPA 2L4KA 1AD5A 4D8KA 2IUGA 3MAZA 2H5KA 2ABLA 1O4MA 1RQQC 1KA6A 3M7FA 2LQNA 1G83A 4K44A 4K11A 1A1EA 3K2MA 1A1CA 2EL8A 3N84A 1YVHA 4NWFA 1O4EA 1H9OA 2RSYA 1FBVA 2C0OA 4GL9E 1IS0A 4JEGA 1R1SA 5EHPA 1FYRA 3QWXX 3PSJA 2C0TA 4U1PA 1PICA 3VROA 1Z3KA 1AOTF 1O47A 2XP1A 3S9KA 1SHAA 2DX0A 1O4GA 2LCTA 3VS3A 3VRZA 1R1QA 1LKKA 1O4OA 2HUWA 1SPSA 1I3ZA 1X6CA 4FBNA 4FL3A 2HDXA 1TZEE 3PS5A 3MXCA 1A08A 2ETZA 2H8HA 2HDVA 2PNBA 1BFIA 3GXWA 2OZOA 2FO0A 1BLKA 1O44A 5AULA 4OHEA 2EYYA 3BUWB 1K9AA 1RJAA 2CIAA 4EIHA 2CRHA 2AOBA 4U17A 1FU5A 1A09A 1B47A 1LUMA 1BF5A 2L3TA 5DC9A 2PLEA 1LUNA 1YVLA 2MRJA 4F5BA 1AYCA 1LCJA 1R1PA 3IMJA 2Y3AB 1O45A 1JYRA 3N7YA 1O41A 1JYQA 5EELA 3N8MA 4GPLB 5CDWA 1O4JA 4DGXA 3IN8A 2PTKA 3S8NA 3ZNIA 3OVEA 1FMKA 1FBZA 3NHNA 2MC1A 3BUOB 3IN7A 1O4RA 2DM0A 3GXXA 1F1WA 1CJ1A 1CWDL 4F5AA 2L6KA 1JWOA 2EO6A 3QWYA 1XA6A 2CR4A 4L1BB 1O42A 1D4WA 5EG3B 3VRPA 1A1BA 1A1AA 4LUDA 1BFJA 4XZ1A 2JYQA 4M4ZA 2YSXA 4LUEA 1KSWA 1OPKA 2KNOA 3HIZB 1Y1UA 1AOUF 2C9WA 2YU7A 1KC2A 3MXYA 3TL0A 5I6VA 1O4DA 1JYUA 4P9VA 1NZVA 4OHLA 1GRIA 2MK2A 1NRVA 1SPRA
chains in the Genus database with same CATH superfamily
3OP0A 1SHBA 2LRAA 2EU0A 3TKZA 3HCKA 4NWGA 1OO3A 5HKWA 4QSYA 5GJHA 1JU5A 3VGOA 2B3OA 3US4A 3VRNA 2DLYA 2MQIA 1O4NA 2KK6A 2CBLA 1O46A 1O43A 1CWEA 4H1OA 2HCKA 1MW4A 5EHRA 2SRCA 1AB2A 1QCFA 1WQUA 1O4BA 1O49A 1X27A 3VS2A 4F59A 5D0JA 4JGHA 3BKBA 3VS1A 2EYVA 3CXLA 2RMXA 5HKZA 5BO4A 2DVJA 5EEQA 1IJRA 3UYOA 1BHFA 2IZVA 2ECDA 2AUGA 3IMDA 4FL2A 5AXIA 4ROJA 4OHDA 1UURA 1TCEA 2FCIA 1LUIA 1Y57A 2PLDA 3LYVA 2CS0A 3HHMB 2SHPA 2LNXA 1AYAA 4P9ZA 1O4QA 4A4BA 1CSZA 5DC0B 1AYBA 2LNWA 3PQZA 5HKYA 5KAZA 1O4IA 1O4KA 1SHDA 3VRRA 3UF4A 1QADA 2GE9A 1BM2A 2AOAA 1FU6A 1M27A 2Y1MA 3PLFB 1GHUA 2IUIA 3BUMB 1SKJA 1NZLA 1BLJA 4K45A 1ZFPE 2DLZA 5DF6A 4K2RA 3S8OA 1KA7A 2LQWA 4GWFA 1O4FA 2EYZA 5J3XA 1O4HA 2H46E 1BMBA 3OB2B 1A81A 2K79B 2RVFA 1D4TA 1LKLA 4XZ0A 2GSBA 1AYDA 2Y1NA 3GQIB 5IBSA 1HCSB 1LCKA 1BHHB 2QMSA 1O4LA 2CI9A 1OO4A 1OPLA 3VS7A 1BKLA 2EKXA 3VRQA 3EAZA 1UUSA 4E68A 3C7IA 2EO3A 2K7AB 2OQ1A 3PSKA 1HCTB 4OHHA 3VS4A 4A4CA 1A07A 1O4CA 1X0NA 4H34A 1O48A 1RPYA 4JE4A 3EACA 2C0IA 2MRKA 4TZIA 3OV1A 1P13A 1O4PA 3OB1B 5GJIA 3PFVA 3VS6A 4EY0A 3CBLA 3KFJA 2RORA 3WA4A 4DGPA 3VS0A 1BHHA 3BUXB 3CWGA 2VIFA 4X6SA 1D1ZA 2BBUA 3CD3A 2HMHA 5IBMA 3VS5A 1BKMA 1QG1E 2CI8A 2IUHA 2EOBA 1O4AA 1MILA 4E93A 5DC4A 1FHSA 3T04A 3S8LA 1M61A 3BUNB 2DCRA 1LUKA 1CSYA 3VRYA 4OHIA 1BG1A 4WWQA 1F2FA 2PNAA 3PJPA 2L4KA 1AD5A 4D8KA 2IUGA 3MAZA 2H5KA 2ABLA 1O4MA 1RQQC 1KA6A 3M7FA 2LQNA 1G83A 4K44A 4K11A 1A1EA 3K2MA 1A1CA 2EL8A 3N84A 1YVHA 4NWFA 1O4EA 1H9OA 2RSYA 1FBVA 2C0OA 4GL9E 1IS0A 4JEGA 1R1SA 5EHPA 1FYRA 3QWXX 3PSJA 2C0TA 4U1PA 1PICA 3VROA 1Z3KA 1AOTF 1O47A 2XP1A 3S9KA 1SHAA 2DX0A 1O4GA 2LCTA 3VS3A 3VRZA 1R1QA 1LKKA 1O4OA 2HUWA 1SPSA 1I3ZA 1X6CA 4FBNA 4FL3A 2HDXA 1TZEE 3PS5A 3MXCA 1A08A 2ETZA 2H8HA 2HDVA 2PNBA 1BFIA 3GXWA 2OZOA 2FO0A 1BLKA 1O44A 5AULA 4OHEA 2EYYA 3BUWB 1K9AA 1RJAA 2CIAA 4EIHA 2CRHA 2AOBA 4U17A 1FU5A 1A09A 1B47A 1LUMA 1BF5A 2L3TA 5DC9A 2PLEA 1LUNA 1YVLA 2MRJA 4F5BA 1AYCA 1LCJA 1R1PA 3IMJA 2Y3AB 1O45A 1JYRA 3N7YA 1O41A 1JYQA 5EELA 3N8MA 4GPLB 5CDWA 1O4JA 4DGXA 3IN8A 2PTKA 3S8NA 3ZNIA 3OVEA 1FMKA 1FBZA 3NHNA 2MC1A 3BUOB 3IN7A 1O4RA 2KGYA 2DM0A 3GXXA 1F1WA 1CJ1A 1CWDL 4F5AA 2L6KA 1JWOA 2EO6A 3QWYA 1XA6A 2CR4A 4L1BB 1O42A 3K2TA 1D4WA 5EG3B 3VRPA 1A1BA 1A1AA 4LUDA 1BFJA 4XZ1A 2JYQA 4M4ZA 2YSXA 4LUEA 1KSWA 1OPKA 2KNOA 3HIZB 1Y1UA 1AOUF 2C9WA 2YU7A 1KC2A 3MXYA 3TL0A 5I6VA 1O4DA 1JYUA 4P9VA 1NZVA 4OHLA 1GRIA 2MK2A 1NRVA 1SPRA
chains in the Genus database with same CATH topology
3OP0A 1SHBA 2EU0A 3TKZA 3HCKA 4NWGA 1OO3A 5HKWA 4QSYA 5GJHA 1JU5A 3VGOA 2B3OA 3US4A 3VRNA 2DLYA 2MQIA 1O4NA 2KK6A 2CBLA 1O46A 1O43A 1CWEA 4H1OA 2HCKA 1MW4A 5EHRA 2SRCA 1AB2A 1QCFA 1WQUA 1O4BA 1O49A 1X27A 3VS2A 4F59A 5D0JA 4JGHA 3BKBA 3VS1A 2EYVA 3CXLA 2RMXA 5HKZA 5BO4A 2DVJA 5EEQA 1IJRA 3UYOA 1BHFA 2IZVA 2ECDA 2AUGA 3IMDA 4FL2A 5AXIA 4ROJA 4OHDA 1UURA 1TCEA 2FCIA 1LUIA 1Y57A 2PLDA 2CS0A 3HHMB 2SHPA 2LNXA 1AYAA 4P9ZA 1O4QA 4A4BA 1CSZA 5DC0B 1AYBA 2LNWA 3PQZA 5HKYA 5KAZA 1O4IA 1O4KA 1SHDA 3VRRA 3UF4A 1QADA 2GE9A 1BM2A 2AOAA 1FU6A 1M27A 2Y1MA 3PLFB 1GHUA 2IUIA 3BUMB 1SKJA 1NZLA 1BLJA 4K45A 1ZFPE 2DLZA 5DF6A 4K2RA 3S8OA 1KA7A 2LQWA 4GWFA 1O4FA 2EYZA 5J3XA 1O4HA 2H46E 1BMBA 3OB2B 1A81A 2K79B 2RVFA 1D4TA 1LKLA 4XZ0A 2GSBA 1AYDA 2Y1NA 3GQIB 5IBSA 1HCSB 1LCKA 1BHHB 2QMSA 1O4LA 2CI9A 1OO4A 1OPLA 3VS7A 1BKLA 2EKXA 3VRQA 3EAZA 1UUSA 4E68A 3C7IA 2EO3A 2K7AB 2OQ1A 3PSKA 1HCTB 4OHHA 3VS4A 4A4CA 1A07A 1O4CA 1X0NA 4H34A 1O48A 1RPYA 4JE4A 3EACA 2C0IA 2MRKA 4TZIA 3OV1A 1P13A 1O4PA 3OB1B 5GJIA 3PFVA 3VS6A 4EY0A 3CBLA 3KFJA 2RORA 3WA4A 4DGPA 3VS0A 1BHHA 3BUXB 3CWGA 2VIFA 4X6SA 1D1ZA 2BBUA 3CD3A 2HMHA 5IBMA 3VS5A 1BKMA 1QG1E 2CI8A 2IUHA 2EOBA 1O4AA 1MILA 4E93A 5DC4A 1FHSA 3T04A 3S8LA 1M61A 3BUNB 2DCRA 1LUKA 1CSYA 3VRYA 4OHIA 1BG1A 4WWQA 1F2FA 2PNAA 3PJPA 2L4KA 1AD5A 4D8KA 2IUGA 3MAZA 2H5KA 2ABLA 1O4MA 1RQQC 1KA6A 3M7FA 2LQNA 1G83A 4K44A 4K11A 1A1EA 3K2MA 1A1CA 2EL8A 3N84A 1YVHA 4NWFA 1O4EA 1H9OA 2RSYA 1FBVA 2C0OA 4GL9E 1IS0A 4JEGA 1R1SA 5EHPA 1FYRA 3QWXX 3PSJA 2C0TA 4U1PA 1PICA 3VROA 1Z3KA 1AOTF 1O47A 2XP1A 3S9KA 1SHAA 2DX0A 1O4GA 2LCTA 3VS3A 3VRZA 1R1QA 1LKKA 1O4OA 2HUWA 1SPSA 1I3ZA 1X6CA 4FBNA 4FL3A 2HDXA 1TZEE 3PS5A 3MXCA 1A08A 2ETZA 2H8HA 2HDVA 2PNBA 1BFIA 3GXWA 2OZOA 2FO0A 1BLKA 1O44A 5AULA 4OHEA 2EYYA 3BUWB 1K9AA 1RJAA 2CIAA 4EIHA 2CRHA 2AOBA 4U17A 1FU5A 1A09A 1B47A 1LUMA 1BF5A 2L3TA 5DC9A 2PLEA 1LUNA 1YVLA 2MRJA 4F5BA 1AYCA 1LCJA 1R1PA 3IMJA 2Y3AB 1O45A 1JYRA 3N7YA 1O41A 1JYQA 5EELA 3N8MA 4GPLB 5CDWA 1O4JA 4DGXA 3IN8A 2PTKA 3S8NA 3ZNIA 3OVEA 1FMKA 1FBZA 3NHNA 2MC1A 3BUOB 3IN7A 1O4RA 2DM0A 3GXXA 1F1WA 1CJ1A 1CWDL 4F5AA 2L6KA 1JWOA 2EO6A 3QWYA 1XA6A 2CR4A 4L1BB 1O42A 1D4WA 5EG3B 3VRPA 1A1BA 1A1AA 4LUDA 1BFJA 4XZ1A 2JYQA 4M4ZA 2YSXA 4LUEA 1KSWA 1OPKA 2KNOA 3HIZB 1Y1UA 1AOUF 2C9WA 2YU7A 1KC2A 3MXYA 3TL0A 5I6VA 1O4DA 1JYUA 4P9VA 1NZVA 4OHLA 1GRIA 2MK2A 1NRVA 1SPRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OP0 A;  1SHB A;  2EU0 A;  3TKZ A;  3HCK A;  4NWG A;  1OO3 A;  5HKW A;  4QSY A;  5GJH A;  1JU5 A;  3VGO A;  2B3O A;  3US4 A;  3VRN A;  2DLY A;  2MQI A;  1O4N A;  2KK6 A;  2CBL A;  1O46 A;  1O43 A;  1CWE A;  4H1O A;  2HCK A;  1MW4 A;  5EHR A;  2SRC A;  1AB2 A;  1QCF A;  1WQU A;  1O4B A;  1O49 A;  1X27 A;  3VS2 A;  4F59 A;  5D0J A;  4JGH A;  3BKB A;  3VS1 A;  2EYV A;  3CXL A;  2RMX A;  5HKZ A;  5BO4 A;  2DVJ A;  5EEQ A;  1IJR A;  3UYO A;  1BHF A;  2IZV A;  2ECD A;  2AUG A;  3IMD A;  4FL2 A;  5AXI A;  4ROJ A;  4OHD A;  1UUR A;  1TCE A;  2FCI A;  1LUI A;  1Y57 A;  2PLD A;  2CS0 A;  3HHM B;  2SHP A;  2LNX A;  1AYA A;  4P9Z A;  1O4Q A;  4A4B A;  1CSZ A;  5DC0 B;  1AYB A;  2LNW A;  3PQZ A;  5HKY A;  5KAZ A;  1O4I A;  1O4K A;  1SHD A;  3VRR A;  3UF4 A;  1QAD A;  2GE9 A;  1BM2 A;  2AOA A;  1FU6 A;  1M27 A;  2Y1M A;  3PLF B;  1GHU A;  2IUI A;  3BUM B;  1SKJ A;  1NZL A;  1BLJ A;  4K45 A;  1ZFP E;  2DLZ A;  5DF6 A;  4K2R A;  3S8O A;  1KA7 A;  2LQW A;  4GWF A;  1O4F A;  2EYZ A;  5J3X A;  1O4H A;  2H46 E;  1BMB A;  3OB2 B;  1A81 A;  2K79 B;  2RVF A;  1D4T A;  1LKL A;  4XZ0 A;  2GSB A;  1AYD A;  2Y1N A;  3GQI B;  5IBS A;  1HCS B;  1LCK A;  1BHH B;  2QMS A;  1O4L A;  2CI9 A;  1OO4 A;  1OPL A;  3VS7 A;  1BKL A;  2EKX A;  3VRQ A;  3EAZ A;  1UUS A;  4E68 A;  3C7I A;  2EO3 A;  2K7A B;  2OQ1 A;  3PSK A;  1HCT B;  4OHH A;  3VS4 A;  4A4C A;  1A07 A;  1O4C A;  1X0N A;  4H34 A;  1O48 A;  1RPY A;  4JE4 A;  3EAC A;  2C0I A;  2MRK A;  4TZI A;  3OV1 A;  1P13 A;  1O4P A;  3OB1 B;  5GJI A;  3PFV A;  3VS6 A;  4EY0 A;  3CBL A;  3KFJ A;  2ROR A;  3WA4 A;  4DGP A;  3VS0 A;  1BHH A;  3BUX B;  3CWG A;  2VIF A;  4X6S A;  1D1Z A;  2BBU A;  3CD3 A;  2HMH A;  5IBM A;  3VS5 A;  1BKM A;  1QG1 E;  2CI8 A;  2IUH A;  2EOB A;  1O4A A;  1MIL A;  4E93 A;  5DC4 A;  1FHS A;  3T04 A;  3S8L A;  1M61 A;  3BUN B;  2DCR A;  1LUK A;  1CSY A;  3VRY A;  4OHI A;  1BG1 A;  4WWQ A;  1F2F A;  2PNA A;  3PJP A;  2L4K A;  1AD5 A;  4D8K A;  2IUG A;  3MAZ A;  2H5K A;  2ABL A;  1O4M A;  1RQQ C;  1KA6 A;  3M7F A;  2LQN A;  1G83 A;  4K44 A;  4K11 A;  1A1E A;  3K2M A;  1A1C A;  2EL8 A;  3N84 A;  1YVH A;  4NWF A;  1O4E A;  1H9O A;  2RSY A;  1FBV A;  2C0O A;  4GL9 E;  1IS0 A;  4JEG A;  1R1S A;  5EHP A;  1FYR A;  3QWX X;  3PSJ A;  2C0T A;  4U1P A;  1PIC A;  3VRO A;  1Z3K A;  1AOT F;  1O47 A;  2XP1 A;  3S9K A;  1SHA A;  2DX0 A;  1O4G A;  2LCT A;  3VS3 A;  3VRZ A;  1R1Q A;  1LKK A;  1O4O A;  2HUW A;  1SPS A;  1I3Z A;  1X6C A;  4FBN A;  4FL3 A;  2HDX A;  1TZE E;  3PS5 A;  3MXC A;  1A08 A;  2ETZ A;  2H8H A;  2HDV A;  2PNB A;  1BFI A;  3GXW A;  2OZO A;  2FO0 A;  1BLK A;  1O44 A;  5AUL A;  4OHE A;  2EYY A;  3BUW B;  1K9A A;  1RJA A;  2CIA A;  4EIH A;  2CRH A;  2AOB A;  4U17 A;  1FU5 A;  1A09 A;  1B47 A;  1LUM A;  1BF5 A;  2L3T A;  5DC9 A;  2PLE A;  1LUN A;  1YVL A;  2MRJ A;  4F5B A;  1AYC A;  1LCJ A;  1R1P A;  3IMJ A;  2Y3A B;  1O45 A;  1JYR A;  3N7Y A;  1O41 A;  1JYQ A;  5EEL A;  3N8M A;  4GPL B;  5CDW A;  1O4J A;  4DGX A;  3IN8 A;  2PTK A;  3S8N A;  3ZNI A;  3OVE A;  1FMK A;  1FBZ A;  3NHN A;  2MC1 A;  3BUO B;  3IN7 A;  1O4R A;  2DM0 A;  3GXX A;  1F1W A;  1CJ1 A;  1CWD L;  4F5A A;  2L6K A;  1JWO A;  2EO6 A;  3QWY A;  1XA6 A;  2CR4 A;  4L1B B;  1O42 A;  1D4W A;  5EG3 B;  3VRP A;  1A1B A;  1A1A A;  4LUD A;  1BFJ A;  4XZ1 A;  2JYQ A;  4M4Z A;  2YSX A;  4LUE A;  1KSW A;  1OPK A;  2KNO A;  3HIZ B;  1Y1U A;  1AOU F;  2C9W A;  2YU7 A;  1KC2 A;  3MXY A;  3TL0 A;  5I6V A;  1O4D A;  1JYU A;  4P9V A;  1NZV A;  4OHL A;  1GRI A;  2MK2 A;  1NRV A;  1SPR A; 
#chains in the Genus database with same CATH topology
 3OP0 A;  1SHB A;  2LRA A;  2EU0 A;  3TKZ A;  3HCK A;  4NWG A;  1OO3 A;  5HKW A;  4QSY A;  5GJH A;  1JU5 A;  3VGO A;  2B3O A;  3US4 A;  3VRN A;  2DLY A;  2MQI A;  1O4N A;  2KK6 A;  2CBL A;  1O46 A;  1O43 A;  1CWE A;  4H1O A;  2HCK A;  1MW4 A;  5EHR A;  2SRC A;  1AB2 A;  1QCF A;  1WQU A;  1O4B A;  1O49 A;  1X27 A;  3VS2 A;  4F59 A;  5D0J A;  4JGH A;  3BKB A;  3VS1 A;  2EYV A;  3CXL A;  2RMX A;  5HKZ A;  5BO4 A;  2DVJ A;  5EEQ A;  1IJR A;  3UYO A;  1BHF A;  2IZV A;  2ECD A;  2AUG A;  3IMD A;  4FL2 A;  5AXI A;  4ROJ A;  4OHD A;  1UUR A;  1TCE A;  2FCI A;  1LUI A;  1Y57 A;  2PLD A;  3LYV A;  2CS0 A;  3HHM B;  2SHP A;  2LNX A;  1AYA A;  4P9Z A;  1O4Q A;  4A4B A;  1CSZ A;  5DC0 B;  1AYB A;  2LNW A;  3PQZ A;  5HKY A;  5KAZ A;  1O4I A;  1O4K A;  1SHD A;  3VRR A;  3UF4 A;  1QAD A;  2GE9 A;  1BM2 A;  2AOA A;  1FU6 A;  1M27 A;  2Y1M A;  3PLF B;  1GHU A;  2IUI A;  3BUM B;  1SKJ A;  1NZL A;  1BLJ A;  4K45 A;  1ZFP E;  2DLZ A;  5DF6 A;  4K2R A;  3S8O A;  1KA7 A;  2LQW A;  4GWF A;  1O4F A;  2EYZ A;  5J3X A;  1O4H A;  2H46 E;  1BMB A;  3OB2 B;  1A81 A;  2K79 B;  2RVF A;  1D4T A;  1LKL A;  4XZ0 A;  2GSB A;  1AYD A;  2Y1N A;  3GQI B;  5IBS A;  1HCS B;  1LCK A;  1BHH B;  2QMS A;  1O4L A;  2CI9 A;  1OO4 A;  1OPL A;  3VS7 A;  1BKL A;  2EKX A;  3VRQ A;  3EAZ A;  1UUS A;  4E68 A;  3C7I A;  2EO3 A;  2K7A B;  2OQ1 A;  3PSK A;  1HCT B;  4OHH A;  3VS4 A;  4A4C A;  1A07 A;  1O4C A;  1X0N A;  4H34 A;  1O48 A;  1RPY A;  4JE4 A;  3EAC A;  2C0I A;  2MRK A;  4TZI A;  3OV1 A;  1P13 A;  1O4P A;  3OB1 B;  5GJI A;  3PFV A;  3VS6 A;  4EY0 A;  3CBL A;  3KFJ A;  2ROR A;  3WA4 A;  4DGP A;  3VS0 A;  1BHH A;  3BUX B;  3CWG A;  2VIF A;  4X6S A;  1D1Z A;  2BBU A;  3CD3 A;  2HMH A;  5IBM A;  3VS5 A;  1BKM A;  1QG1 E;  2CI8 A;  2IUH A;  2EOB A;  1O4A A;  1MIL A;  4E93 A;  5DC4 A;  1FHS A;  3T04 A;  3S8L A;  1M61 A;  3BUN B;  2DCR A;  1LUK A;  1CSY A;  3VRY A;  4OHI A;  1BG1 A;  4WWQ A;  1F2F A;  2PNA A;  3PJP A;  2L4K A;  1AD5 A;  4D8K A;  2IUG A;  3MAZ A;  2H5K A;  2ABL A;  1O4M A;  1RQQ C;  1KA6 A;  3M7F A;  2LQN A;  1G83 A;  4K44 A;  4K11 A;  1A1E A;  3K2M A;  1A1C A;  2EL8 A;  3N84 A;  1YVH A;  4NWF A;  1O4E A;  1H9O A;  2RSY A;  1FBV A;  2C0O A;  4GL9 E;  1IS0 A;  4JEG A;  1R1S A;  5EHP A;  1FYR A;  3QWX X;  3PSJ A;  2C0T A;  4U1P A;  1PIC A;  3VRO A;  1Z3K A;  1AOT F;  1O47 A;  2XP1 A;  3S9K A;  1SHA A;  2DX0 A;  1O4G A;  2LCT A;  3VS3 A;  3VRZ A;  1R1Q A;  1LKK A;  1O4O A;  2HUW A;  1SPS A;  1I3Z A;  1X6C A;  4FBN A;  4FL3 A;  2HDX A;  1TZE E;  3PS5 A;  3MXC A;  1A08 A;  2ETZ A;  2H8H A;  2HDV A;  2PNB A;  1BFI A;  3GXW A;  2OZO A;  2FO0 A;  1BLK A;  1O44 A;  5AUL A;  4OHE A;  2EYY A;  3BUW B;  1K9A A;  1RJA A;  2CIA A;  4EIH A;  2CRH A;  2AOB A;  4U17 A;  1FU5 A;  1A09 A;  1B47 A;  1LUM A;  1BF5 A;  2L3T A;  5DC9 A;  2PLE A;  1LUN A;  1YVL A;  2MRJ A;  4F5B A;  1AYC A;  1LCJ A;  1R1P A;  3IMJ A;  2Y3A B;  1O45 A;  1JYR A;  3N7Y A;  1O41 A;  1JYQ A;  5EEL A;  3N8M A;  4GPL B;  5CDW A;  1O4J A;  4DGX A;  3IN8 A;  2PTK A;  3S8N A;  3ZNI A;  3OVE A;  1FMK A;  1FBZ A;  3NHN A;  2MC1 A;  3BUO B;  3IN7 A;  1O4R A;  2KGY A;  2DM0 A;  3GXX A;  1F1W A;  1CJ1 A;  1CWD L;  4F5A A;  2L6K A;  1JWO A;  2EO6 A;  3QWY A;  1XA6 A;  2CR4 A;  4L1B B;  1O42 A;  3K2T A;  1D4W A;  5EG3 B;  3VRP A;  1A1B A;  1A1A A;  4LUD A;  1BFJ A;  4XZ1 A;  2JYQ A;  4M4Z A;  2YSX A;  4LUE A;  1KSW A;  1OPK A;  2KNO A;  3HIZ B;  1Y1U A;  1AOU F;  2C9W A;  2YU7 A;  1KC2 A;  3MXY A;  3TL0 A;  5I6V A;  1O4D A;  1JYU A;  4P9V A;  1NZV A;  4OHL A;  1GRI A;  2MK2 A;  1NRV A;  1SPR A; 
#chains in the Genus database with same CATH homology
 3OP0 A;  1SHB A;  2EU0 A;  3TKZ A;  3HCK A;  4NWG A;  1OO3 A;  5HKW A;  4QSY A;  5GJH A;  1JU5 A;  3VGO A;  2B3O A;  3US4 A;  3VRN A;  2DLY A;  2MQI A;  1O4N A;  2KK6 A;  2CBL A;  1O46 A;  1O43 A;  1CWE A;  4H1O A;  2HCK A;  1MW4 A;  5EHR A;  2SRC A;  1AB2 A;  1QCF A;  1WQU A;  1O4B A;  1O49 A;  1X27 A;  3VS2 A;  4F59 A;  5D0J A;  4JGH A;  3BKB A;  3VS1 A;  2EYV A;  3CXL A;  2RMX A;  5HKZ A;  5BO4 A;  2DVJ A;  5EEQ A;  1IJR A;  3UYO A;  1BHF A;  2IZV A;  2ECD A;  2AUG A;  3IMD A;  4FL2 A;  5AXI A;  4ROJ A;  4OHD A;  1UUR A;  1TCE A;  2FCI A;  1LUI A;  1Y57 A;  2PLD A;  2CS0 A;  3HHM B;  2SHP A;  2LNX A;  1AYA A;  4P9Z A;  1O4Q A;  4A4B A;  1CSZ A;  5DC0 B;  1AYB A;  2LNW A;  3PQZ A;  5HKY A;  5KAZ A;  1O4I A;  1O4K A;  1SHD A;  3VRR A;  3UF4 A;  1QAD A;  2GE9 A;  1BM2 A;  2AOA A;  1FU6 A;  1M27 A;  2Y1M A;  3PLF B;  1GHU A;  2IUI A;  3BUM B;  1SKJ A;  1NZL A;  1BLJ A;  4K45 A;  1ZFP E;  2DLZ A;  5DF6 A;  4K2R A;  3S8O A;  1KA7 A;  2LQW A;  4GWF A;  1O4F A;  2EYZ A;  5J3X A;  1O4H A;  2H46 E;  1BMB A;  3OB2 B;  1A81 A;  2K79 B;  2RVF A;  1D4T A;  1LKL A;  4XZ0 A;  2GSB A;  1AYD A;  2Y1N A;  3GQI B;  5IBS A;  1HCS B;  1LCK A;  1BHH B;  2QMS A;  1O4L A;  2CI9 A;  1OO4 A;  1OPL A;  3VS7 A;  1BKL A;  2EKX A;  3VRQ A;  3EAZ A;  1UUS A;  4E68 A;  3C7I A;  2EO3 A;  2K7A B;  2OQ1 A;  3PSK A;  1HCT B;  4OHH A;  3VS4 A;  4A4C A;  1A07 A;  1O4C A;  1X0N A;  4H34 A;  1O48 A;  1RPY A;  4JE4 A;  3EAC A;  2C0I A;  2MRK A;  4TZI A;  3OV1 A;  1P13 A;  1O4P A;  3OB1 B;  5GJI A;  3PFV A;  3VS6 A;  4EY0 A;  3CBL A;  3KFJ A;  2ROR A;  3WA4 A;  4DGP A;  3VS0 A;  1BHH A;  3BUX B;  3CWG A;  2VIF A;  4X6S A;  1D1Z A;  2BBU A;  3CD3 A;  2HMH A;  5IBM A;  3VS5 A;  1BKM A;  1QG1 E;  2CI8 A;  2IUH A;  2EOB A;  1O4A A;  1MIL A;  4E93 A;  5DC4 A;  1FHS A;  3T04 A;  3S8L A;  1M61 A;  3BUN B;  2DCR A;  1LUK A;  1CSY A;  3VRY A;  4OHI A;  1BG1 A;  4WWQ A;  1F2F A;  2PNA A;  3PJP A;  2L4K A;  1AD5 A;  4D8K A;  2IUG A;  3MAZ A;  2H5K A;  2ABL A;  1O4M A;  1RQQ C;  1KA6 A;  3M7F A;  2LQN A;  1G83 A;  4K44 A;  4K11 A;  1A1E A;  3K2M A;  1A1C A;  2EL8 A;  3N84 A;  1YVH A;  4NWF A;  1O4E A;  1H9O A;  2RSY A;  1FBV A;  2C0O A;  4GL9 E;  1IS0 A;  4JEG A;  1R1S A;  5EHP A;  1FYR A;  3QWX X;  3PSJ A;  2C0T A;  4U1P A;  1PIC A;  3VRO A;  1Z3K A;  1AOT F;  1O47 A;  2XP1 A;  3S9K A;  1SHA A;  2DX0 A;  1O4G A;  2LCT A;  3VS3 A;  3VRZ A;  1R1Q A;  1LKK A;  1O4O A;  2HUW A;  1SPS A;  1I3Z A;  1X6C A;  4FBN A;  4FL3 A;  2HDX A;  1TZE E;  3PS5 A;  3MXC A;  1A08 A;  2ETZ A;  2H8H A;  2HDV A;  2PNB A;  1BFI A;  3GXW A;  2OZO A;  2FO0 A;  1BLK A;  1O44 A;  5AUL A;  4OHE A;  2EYY A;  3BUW B;  1K9A A;  1RJA A;  2CIA A;  4EIH A;  2CRH A;  2AOB A;  4U17 A;  1FU5 A;  1A09 A;  1B47 A;  1LUM A;  1BF5 A;  2L3T A;  5DC9 A;  2PLE A;  1LUN A;  1YVL A;  2MRJ A;  4F5B A;  1AYC A;  1LCJ A;  1R1P A;  3IMJ A;  2Y3A B;  1O45 A;  1JYR A;  3N7Y A;  1O41 A;  1JYQ A;  5EEL A;  3N8M A;  4GPL B;  5CDW A;  1O4J A;  4DGX A;  3IN8 A;  2PTK A;  3S8N A;  3ZNI A;  3OVE A;  1FMK A;  1FBZ A;  3NHN A;  2MC1 A;  3BUO B;  3IN7 A;  1O4R A;  2DM0 A;  3GXX A;  1F1W A;  1CJ1 A;  1CWD L;  4F5A A;  2L6K A;  1JWO A;  2EO6 A;  3QWY A;  1XA6 A;  2CR4 A;  4L1B B;  1O42 A;  1D4W A;  5EG3 B;  3VRP A;  1A1B A;  1A1A A;  4LUD A;  1BFJ A;  4XZ1 A;  2JYQ A;  4M4Z A;  2YSX A;  4LUE A;  1KSW A;  1OPK A;  2KNO A;  3HIZ B;  1Y1U A;  1AOU F;  2C9W A;  2YU7 A;  1KC2 A;  3MXY A;  3TL0 A;  5I6V A;  1O4D A;  1JYU A;  4P9V A;  1NZV A;  4OHL A;  1GRI A;  2MK2 A;  1NRV A;  1SPR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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