3MXCA

Structures of grb2-sh2 domain and aicd peptide complexes reveal a conformational switch and their functional implications.
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
98
structure length
98
Chain Sequence
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 24
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 2010-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 3mxcA00
1NZVA 4WWQA 2K79B 4DGPA 5HKYA 4K44A 1AYBA 1A1EA 1BLJA 1X0NA 1O45A 3VRYA 1D4WA 2VIFA 3BUMB 3OB2B 1IS0A 1LCKA 1LUIA 2L3TA 2FCIA 2HDXA 2RSYA 4GPLB 2RVFA 4QSYA 2MK2A 3PS5A 2XP1A 2EYZA 1FBZA 2AOAA 3HIZB 2SHPA 3EAZA 2GSBA 2EO6A 2YSXA 2C0OA 4NWGA 4OHHA 2CBLA 3VRRA 2HMHA 5I6VA 1BF5A 1A08A 3VS7A 5AULA 1BFIA 1UUSA 1AB2A 3VS5A 3QWXX 1NRVA 4K45A 2FO0A 5DC4A 4GWFA 2DM0A 4FL2A 1MILA 1HCTB 4OHDA 3BKBA 1JWOA 1O4BA 4JE4A 1CWDL 3K2MA 3S8OA 2DX0A 2RMXA 3N8MA 1TZEE 3BUNB 1JU5A 1OPLA 2H46E 2L4KA 3S9KA 2EOBA 2BBUA 5GJIA 4U1PA 2AUGA 3EACA 1MW4A 3OB1B 1BHHB 2CR4A 5EHRA 4LUDA 3NHNA 5CDWA 1BKLA 2L6KA 3OVEA 4EY0A 1LKLA 4K11A 3GQIB 4F5BA 1O42A 2CS0A 4E93A 1F1WA 1O4KA 1D4TA 2PNAA 1BHHA 1CWEA 2CIAA 3VS4A 1SHDA 3VROA 5EELA 1O4DA 2ETZA 2LQWA 5EHPA 2KNOA 3IMJA 3PFVA 4NWFA 1HCSB 2LNXA 1JYQA 1O4JA 3PJPA 1O4GA 2CI9A 2DVJA 1G83A 2PLEA 1X27A 1QCFA 3VS6A 2C9WA 1AYDA 1RPYA 1SPRA 3CD3A 4JEGA 1O4OA 3US4A 1A07A 2EU0A 1O46A 4EIHA 3OV1A 3TL0A 3VS0A 3CBLA 4P9VA 1O4LA 2MRKA 5HKWA 2DCRA 3VGOA 4F59A 4H1OA 1Z3KA 4D8KA 1SKJA 1BFJA 1CSZA 1BLKA 4ROJA 2YU7A 1CSYA 1GHUA 5DC9A 4DGXA 1KA6A 3MXCA 2RORA 2IUIA 4JGHA 2Y1NA 2DLYA 4OHIA 1Y57A 1FMKA 2OZOA 1O4CA 2PNBA 1CJ1A 1OPKA 1O43A 4F5AA 1AD5A 3VS2A 1XA6A 2ECDA 3GXWA 5D0JA 5IBMA 1TCEA 2Y1MA 1M61A 2CI8A 2EKXA 1RJAA 1FYRA 2EYYA 1LUNA 3C7IA 3GXXA 3T04A 4X6SA 1BKMA 1O4NA 1GRIA 1RQQC 5AXIA 4XZ1A 1KC2A 4U17A 2LCTA 1B47A 1O4EA 2EO3A 3VRPA 2C0IA 2IUGA 3MAZA 4OHLA 1I3ZA 1A1AA 4XZ0A 5DC0B 5IBSA 3BUXB 2IUHA 1FBVA 5BO4A 3HCKA 3PQZA 1AYCA 1Y1UA 1OO4A 2H5KA 1A1CA 3CWGA 4A4BA 2H8HA 2KK6A 3UF4A 1FU6A 2DLZA 2OQ1A 1NZLA 3TKZA 1O47A 3VRQA 3IN8A 1BM2A 1ZFPE 1O48A 3HHMB 4E68A 3WA4A 1WQUA 3IMDA 2Y3AB 2LNWA 2HDVA 1O4PA 4M4ZA 3UYOA 4FL3A 2PLDA 3MXYA 1LKKA 1SPSA 5GJHA 1R1QA 2K7AB 1OO3A 2JYQA 4K2RA 2CRHA 2MQIA 4H34A 1AYAA 3PSKA 1O4AA 1PICA 1LUMA 1A81A 1FU5A 2QMSA 2LQNA 5EEQA 4A4CA 1AOTF 2HCKA 1A1BA 3ZNIA 3PLFB 1M27A 1JYUA 1QADA 5EG3B 1O44A 1R1SA 1YVHA 2EYVA 3N7YA 1P13A 2PTKA 1K9AA 5KAZA 1D1ZA 1KSWA 2MC1A 4P9ZA 2IZVA 2SRCA 1O4IA 1O41A 1LCJA 3M7FA 4LUEA 3N84A 3VS1A 4GL9E 3PSJA 2B3OA 1QG1E 1IJRA 1SHBA 1AOUF 2ABLA 3BUWB 4OHEA 3VS3A 1O4RA 1O4FA 5DF6A 3VRNA 3KFJA 3QWYA 3S8LA 1H9OA 1BHFA 3CXLA 5HKZA 1FHSA 1O4MA 1O4HA 1SHAA 2GE9A 3VRZA 1UURA 1O4QA 2HUWA 3BUOB 1O49A 2EL8A 2AOBA 3S8NA 3OP0A 1KA7A 4TZIA 1JYRA 1LUKA 2MRJA 1X6CA 1R1PA 1BG1A 1A09A 2C0TA 3IN7A 4L1BB 1BMBA 4FBNA 1YVLA 5J3XA 1F2FA
chains in the Genus database with same CATH superfamily
1NZVA 4WWQA 2K79B 4DGPA 5HKYA 4K44A 1AYBA 1A1EA 1BLJA 1X0NA 1O45A 3VRYA 1D4WA 2VIFA 3BUMB 3K2TA 3OB2B 1IS0A 1LCKA 1LUIA 2L3TA 2FCIA 2HDXA 2RSYA 4GPLB 2RVFA 4QSYA 2MK2A 3PS5A 2XP1A 2EYZA 1FBZA 2AOAA 3HIZB 2SHPA 3EAZA 2GSBA 2EO6A 2YSXA 2C0OA 4NWGA 4OHHA 2CBLA 3VRRA 2HMHA 5I6VA 1BF5A 1A08A 3VS7A 5AULA 1BFIA 1UUSA 1AB2A 3VS5A 3QWXX 1NRVA 4K45A 2FO0A 5DC4A 4GWFA 2DM0A 4FL2A 1MILA 1HCTB 4OHDA 3BKBA 1JWOA 1O4BA 4JE4A 1CWDL 3K2MA 3S8OA 2DX0A 2RMXA 3N8MA 1TZEE 3BUNB 1JU5A 1OPLA 2H46E 2L4KA 3S9KA 2EOBA 2BBUA 5GJIA 4U1PA 2AUGA 3EACA 1MW4A 3OB1B 1BHHB 2CR4A 5EHRA 4LUDA 3NHNA 5CDWA 1BKLA 2L6KA 3OVEA 4EY0A 1LKLA 4K11A 3GQIB 4F5BA 1O42A 2CS0A 4E93A 1F1WA 1O4KA 1D4TA 2PNAA 1BHHA 1CWEA 2CIAA 3VS4A 1SHDA 3VROA 5EELA 1O4DA 2ETZA 2LQWA 5EHPA 2KNOA 3IMJA 3PFVA 4NWFA 1HCSB 2LNXA 1JYQA 1O4JA 3PJPA 1O4GA 2CI9A 2DVJA 1G83A 2PLEA 1X27A 1QCFA 3VS6A 2C9WA 1AYDA 1RPYA 1SPRA 3CD3A 4JEGA 1O4OA 3US4A 1A07A 2EU0A 1O46A 4EIHA 3OV1A 3TL0A 3VS0A 3CBLA 4P9VA 1O4LA 2MRKA 5HKWA 2DCRA 3VGOA 4F59A 4H1OA 1Z3KA 4D8KA 1SKJA 1BFJA 1CSZA 1BLKA 4ROJA 2YU7A 1CSYA 1GHUA 5DC9A 4DGXA 1KA6A 3MXCA 2RORA 2IUIA 4JGHA 2Y1NA 2DLYA 4OHIA 1Y57A 2KGYA 1FMKA 2OZOA 1O4CA 2PNBA 1CJ1A 1OPKA 1O43A 4F5AA 1AD5A 3VS2A 1XA6A 2ECDA 3GXWA 5D0JA 5IBMA 1TCEA 2Y1MA 1M61A 2CI8A 2EKXA 1RJAA 1FYRA 2EYYA 1LUNA 3C7IA 3GXXA 3T04A 4X6SA 1BKMA 1O4NA 1GRIA 1RQQC 5AXIA 4XZ1A 1KC2A 4U17A 2LCTA 1B47A 1O4EA 2EO3A 3VRPA 2C0IA 2IUGA 3MAZA 4OHLA 1I3ZA 1A1AA 4XZ0A 5DC0B 5IBSA 3BUXB 2IUHA 1FBVA 5BO4A 3HCKA 3PQZA 1AYCA 1Y1UA 1OO4A 2H5KA 1A1CA 3CWGA 4A4BA 2H8HA 2KK6A 3UF4A 1FU6A 2DLZA 2OQ1A 1NZLA 3TKZA 1O47A 3VRQA 3IN8A 1BM2A 1ZFPE 1O48A 3HHMB 4E68A 3WA4A 1WQUA 3IMDA 2Y3AB 2LNWA 2HDVA 1O4PA 4M4ZA 3UYOA 4FL3A 2PLDA 3MXYA 1LKKA 1SPSA 5GJHA 1R1QA 2K7AB 1OO3A 2JYQA 4K2RA 2CRHA 2MQIA 4H34A 1AYAA 3PSKA 1O4AA 1PICA 1LUMA 1A81A 1FU5A 2QMSA 2LQNA 5EEQA 4A4CA 1AOTF 2HCKA 1A1BA 3ZNIA 3PLFB 1M27A 1JYUA 1QADA 5EG3B 1O44A 1R1SA 1YVHA 2EYVA 3N7YA 1P13A 2PTKA 1K9AA 5KAZA 1D1ZA 1KSWA 2MC1A 4P9ZA 2IZVA 2SRCA 2LRAA 1O4IA 1O41A 1LCJA 3M7FA 4LUEA 3N84A 3VS1A 4GL9E 3PSJA 2B3OA 1QG1E 1IJRA 1SHBA 1AOUF 2ABLA 3BUWB 4OHEA 3VS3A 1O4RA 1O4FA 5DF6A 3VRNA 3KFJA 3QWYA 3S8LA 3LYVA 1H9OA 1BHFA 3CXLA 5HKZA 1FHSA 1O4MA 1O4HA 1SHAA 2GE9A 3VRZA 1UURA 1O4QA 2HUWA 3BUOB 1O49A 2EL8A 2AOBA 3S8NA 3OP0A 1KA7A 4TZIA 1JYRA 1LUKA 2MRJA 1X6CA 1R1PA 1BG1A 1A09A 2C0TA 3IN7A 4L1BB 1BMBA 4FBNA 1YVLA 5J3XA 1F2FA
chains in the Genus database with same CATH topology
1NZVA 4WWQA 2K79B 4DGPA 5HKYA 4K44A 1AYBA 1A1EA 1BLJA 1X0NA 1O45A 3VRYA 1D4WA 2VIFA 3BUMB 3OB2B 1IS0A 1LCKA 1LUIA 2L3TA 2FCIA 2HDXA 2RSYA 4GPLB 2RVFA 4QSYA 2MK2A 3PS5A 2XP1A 2EYZA 1FBZA 2AOAA 3HIZB 2SHPA 3EAZA 2GSBA 2EO6A 2YSXA 2C0OA 4NWGA 4OHHA 2CBLA 3VRRA 2HMHA 5I6VA 1BF5A 1A08A 3VS7A 5AULA 1BFIA 1UUSA 1AB2A 3VS5A 3QWXX 1NRVA 4K45A 2FO0A 5DC4A 4GWFA 2DM0A 4FL2A 1MILA 1HCTB 4OHDA 3BKBA 1JWOA 1O4BA 4JE4A 1CWDL 3K2MA 3S8OA 2DX0A 2RMXA 3N8MA 1TZEE 3BUNB 1JU5A 1OPLA 2H46E 2L4KA 3S9KA 2EOBA 2BBUA 5GJIA 4U1PA 2AUGA 3EACA 1MW4A 3OB1B 1BHHB 2CR4A 5EHRA 4LUDA 3NHNA 5CDWA 1BKLA 2L6KA 3OVEA 4EY0A 1LKLA 4K11A 3GQIB 4F5BA 1O42A 2CS0A 4E93A 1F1WA 1O4KA 1D4TA 2PNAA 1BHHA 1CWEA 2CIAA 3VS4A 1SHDA 3VROA 5EELA 1O4DA 2ETZA 2LQWA 5EHPA 2KNOA 3IMJA 3PFVA 4NWFA 1HCSB 2LNXA 1JYQA 1O4JA 3PJPA 1O4GA 2CI9A 2DVJA 1G83A 2PLEA 1X27A 1QCFA 3VS6A 2C9WA 1AYDA 1RPYA 1SPRA 3CD3A 4JEGA 1O4OA 3US4A 1A07A 2EU0A 1O46A 4EIHA 3OV1A 3TL0A 3VS0A 3CBLA 4P9VA 1O4LA 2MRKA 5HKWA 2DCRA 3VGOA 4F59A 4H1OA 1Z3KA 4D8KA 1SKJA 1BFJA 1CSZA 1BLKA 4ROJA 2YU7A 1CSYA 1GHUA 5DC9A 4DGXA 1KA6A 3MXCA 2RORA 2IUIA 4JGHA 2Y1NA 2DLYA 4OHIA 1Y57A 1FMKA 2OZOA 1O4CA 2PNBA 1CJ1A 1OPKA 1O43A 4F5AA 1AD5A 3VS2A 1XA6A 2ECDA 3GXWA 5D0JA 5IBMA 1TCEA 2Y1MA 1M61A 2CI8A 2EKXA 1RJAA 1FYRA 2EYYA 1LUNA 3C7IA 3GXXA 3T04A 4X6SA 1BKMA 1O4NA 1GRIA 1RQQC 5AXIA 4XZ1A 1KC2A 4U17A 2LCTA 1B47A 1O4EA 2EO3A 3VRPA 2C0IA 2IUGA 3MAZA 4OHLA 1I3ZA 1A1AA 4XZ0A 5DC0B 5IBSA 3BUXB 2IUHA 1FBVA 5BO4A 3HCKA 3PQZA 1AYCA 1Y1UA 1OO4A 2H5KA 1A1CA 3CWGA 4A4BA 2H8HA 2KK6A 3UF4A 1FU6A 2DLZA 2OQ1A 1NZLA 3TKZA 1O47A 3VRQA 3IN8A 1BM2A 1ZFPE 1O48A 3HHMB 4E68A 3WA4A 1WQUA 3IMDA 2Y3AB 2LNWA 2HDVA 1O4PA 4M4ZA 3UYOA 4FL3A 2PLDA 3MXYA 1LKKA 1SPSA 5GJHA 1R1QA 2K7AB 1OO3A 2JYQA 4K2RA 2CRHA 2MQIA 4H34A 1AYAA 3PSKA 1O4AA 1PICA 1LUMA 1A81A 1FU5A 2QMSA 2LQNA 5EEQA 4A4CA 1AOTF 2HCKA 1A1BA 3ZNIA 3PLFB 1M27A 1JYUA 1QADA 5EG3B 1O44A 1R1SA 1YVHA 2EYVA 3N7YA 1P13A 2PTKA 1K9AA 5KAZA 1D1ZA 1KSWA 2MC1A 4P9ZA 2IZVA 2SRCA 1O4IA 1O41A 1LCJA 3M7FA 4LUEA 3N84A 3VS1A 4GL9E 3PSJA 2B3OA 1QG1E 1IJRA 1SHBA 1AOUF 2ABLA 3BUWB 4OHEA 3VS3A 1O4RA 1O4FA 5DF6A 3VRNA 3KFJA 3QWYA 3S8LA 1H9OA 1BHFA 3CXLA 5HKZA 1FHSA 1O4MA 1O4HA 1SHAA 2GE9A 3VRZA 1UURA 1O4QA 2HUWA 3BUOB 1O49A 2EL8A 2AOBA 3S8NA 3OP0A 1KA7A 4TZIA 1JYRA 1LUKA 2MRJA 1X6CA 1R1PA 1BG1A 1A09A 2C0TA 3IN7A 4L1BB 1BMBA 4FBNA 1YVLA 5J3XA 1F2FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NZV A;  4WWQ A;  2K79 B;  4DGP A;  5HKY A;  4K44 A;  1AYB A;  1A1E A;  1BLJ A;  1X0N A;  1O45 A;  3VRY A;  1D4W A;  2VIF A;  3BUM B;  3OB2 B;  1IS0 A;  1LCK A;  1LUI A;  2L3T A;  2FCI A;  2HDX A;  2RSY A;  4GPL B;  2RVF A;  4QSY A;  2MK2 A;  3PS5 A;  2XP1 A;  2EYZ A;  1FBZ A;  2AOA A;  3HIZ B;  2SHP A;  3EAZ A;  2GSB A;  2EO6 A;  2YSX A;  2C0O A;  4NWG A;  4OHH A;  2CBL A;  3VRR A;  2HMH A;  5I6V A;  1BF5 A;  1A08 A;  3VS7 A;  5AUL A;  1BFI A;  1UUS A;  1AB2 A;  3VS5 A;  3QWX X;  1NRV A;  4K45 A;  2FO0 A;  5DC4 A;  4GWF A;  2DM0 A;  4FL2 A;  1MIL A;  1HCT B;  4OHD A;  3BKB A;  1JWO A;  1O4B A;  4JE4 A;  1CWD L;  3K2M A;  3S8O A;  2DX0 A;  2RMX A;  3N8M A;  1TZE E;  3BUN B;  1JU5 A;  1OPL A;  2H46 E;  2L4K A;  3S9K A;  2EOB A;  2BBU A;  5GJI A;  4U1P A;  2AUG A;  3EAC A;  1MW4 A;  3OB1 B;  1BHH B;  2CR4 A;  5EHR A;  4LUD A;  3NHN A;  5CDW A;  1BKL A;  2L6K A;  3OVE A;  4EY0 A;  1LKL A;  4K11 A;  3GQI B;  4F5B A;  1O42 A;  2CS0 A;  4E93 A;  1F1W A;  1O4K A;  1D4T A;  2PNA A;  1BHH A;  1CWE A;  2CIA A;  3VS4 A;  1SHD A;  3VRO A;  5EEL A;  1O4D A;  2ETZ A;  2LQW A;  5EHP A;  2KNO A;  3IMJ A;  3PFV A;  4NWF A;  1HCS B;  2LNX A;  1JYQ A;  1O4J A;  3PJP A;  1O4G A;  2CI9 A;  2DVJ A;  1G83 A;  2PLE A;  1X27 A;  1QCF A;  3VS6 A;  2C9W A;  1AYD A;  1RPY A;  1SPR A;  3CD3 A;  4JEG A;  1O4O A;  3US4 A;  1A07 A;  2EU0 A;  1O46 A;  4EIH A;  3OV1 A;  3TL0 A;  3VS0 A;  3CBL A;  4P9V A;  1O4L A;  2MRK A;  5HKW A;  2DCR A;  3VGO A;  4F59 A;  4H1O A;  1Z3K A;  4D8K A;  1SKJ A;  1BFJ A;  1CSZ A;  1BLK A;  4ROJ A;  2YU7 A;  1CSY A;  1GHU A;  5DC9 A;  4DGX A;  1KA6 A;  3MXC A;  2ROR A;  2IUI A;  4JGH A;  2Y1N A;  2DLY A;  4OHI A;  1Y57 A;  1FMK A;  2OZO A;  1O4C A;  2PNB A;  1CJ1 A;  1OPK A;  1O43 A;  4F5A A;  1AD5 A;  3VS2 A;  1XA6 A;  2ECD A;  3GXW A;  5D0J A;  5IBM A;  1TCE A;  2Y1M A;  1M61 A;  2CI8 A;  2EKX A;  1RJA A;  1FYR A;  2EYY A;  1LUN A;  3C7I A;  3GXX A;  3T04 A;  4X6S A;  1BKM A;  1O4N A;  1GRI A;  1RQQ C;  5AXI A;  4XZ1 A;  1KC2 A;  4U17 A;  2LCT A;  1B47 A;  1O4E A;  2EO3 A;  3VRP A;  2C0I A;  2IUG A;  3MAZ A;  4OHL A;  1I3Z A;  1A1A A;  4XZ0 A;  5DC0 B;  5IBS A;  3BUX B;  2IUH A;  1FBV A;  5BO4 A;  3HCK A;  3PQZ A;  1AYC A;  1Y1U A;  1OO4 A;  2H5K A;  1A1C A;  3CWG A;  4A4B A;  2H8H A;  2KK6 A;  3UF4 A;  1FU6 A;  2DLZ A;  2OQ1 A;  1NZL A;  3TKZ A;  1O47 A;  3VRQ A;  3IN8 A;  1BM2 A;  1ZFP E;  1O48 A;  3HHM B;  4E68 A;  3WA4 A;  1WQU A;  3IMD A;  2Y3A B;  2LNW A;  2HDV A;  1O4P A;  4M4Z A;  3UYO A;  4FL3 A;  2PLD A;  3MXY A;  1LKK A;  1SPS A;  5GJH A;  1R1Q A;  2K7A B;  1OO3 A;  2JYQ A;  4K2R A;  2CRH A;  2MQI A;  4H34 A;  1AYA A;  3PSK A;  1O4A A;  1PIC A;  1LUM A;  1A81 A;  1FU5 A;  2QMS A;  2LQN A;  5EEQ A;  4A4C A;  1AOT F;  2HCK A;  1A1B A;  3ZNI A;  3PLF B;  1M27 A;  1JYU A;  1QAD A;  5EG3 B;  1O44 A;  1R1S A;  1YVH A;  2EYV A;  3N7Y A;  1P13 A;  2PTK A;  1K9A A;  5KAZ A;  1D1Z A;  1KSW A;  2MC1 A;  4P9Z A;  2IZV A;  2SRC A;  1O4I A;  1O41 A;  1LCJ A;  3M7F A;  4LUE A;  3N84 A;  3VS1 A;  4GL9 E;  3PSJ A;  2B3O A;  1QG1 E;  1IJR A;  1SHB A;  1AOU F;  2ABL A;  3BUW B;  4OHE A;  3VS3 A;  1O4R A;  1O4F A;  5DF6 A;  3VRN A;  3KFJ A;  3QWY A;  3S8L A;  1H9O A;  1BHF A;  3CXL A;  5HKZ A;  1FHS A;  1O4M A;  1O4H A;  1SHA A;  2GE9 A;  3VRZ A;  1UUR A;  1O4Q A;  2HUW A;  3BUO B;  1O49 A;  2EL8 A;  2AOB A;  3S8N A;  3OP0 A;  1KA7 A;  4TZI A;  1JYR A;  1LUK A;  2MRJ A;  1X6C A;  1R1P A;  1BG1 A;  1A09 A;  2C0T A;  3IN7 A;  4L1B B;  1BMB A;  4FBN A;  1YVL A;  5J3X A;  1F2F A; 
#chains in the Genus database with same CATH topology
 1NZV A;  4WWQ A;  2K79 B;  4DGP A;  5HKY A;  4K44 A;  1AYB A;  1A1E A;  1BLJ A;  1X0N A;  1O45 A;  3VRY A;  1D4W A;  2VIF A;  3BUM B;  3K2T A;  3OB2 B;  1IS0 A;  1LCK A;  1LUI A;  2L3T A;  2FCI A;  2HDX A;  2RSY A;  4GPL B;  2RVF A;  4QSY A;  2MK2 A;  3PS5 A;  2XP1 A;  2EYZ A;  1FBZ A;  2AOA A;  3HIZ B;  2SHP A;  3EAZ A;  2GSB A;  2EO6 A;  2YSX A;  2C0O A;  4NWG A;  4OHH A;  2CBL A;  3VRR A;  2HMH A;  5I6V A;  1BF5 A;  1A08 A;  3VS7 A;  5AUL A;  1BFI A;  1UUS A;  1AB2 A;  3VS5 A;  3QWX X;  1NRV A;  4K45 A;  2FO0 A;  5DC4 A;  4GWF A;  2DM0 A;  4FL2 A;  1MIL A;  1HCT B;  4OHD A;  3BKB A;  1JWO A;  1O4B A;  4JE4 A;  1CWD L;  3K2M A;  3S8O A;  2DX0 A;  2RMX A;  3N8M A;  1TZE E;  3BUN B;  1JU5 A;  1OPL A;  2H46 E;  2L4K A;  3S9K A;  2EOB A;  2BBU A;  5GJI A;  4U1P A;  2AUG A;  3EAC A;  1MW4 A;  3OB1 B;  1BHH B;  2CR4 A;  5EHR A;  4LUD A;  3NHN A;  5CDW A;  1BKL A;  2L6K A;  3OVE A;  4EY0 A;  1LKL A;  4K11 A;  3GQI B;  4F5B A;  1O42 A;  2CS0 A;  4E93 A;  1F1W A;  1O4K A;  1D4T A;  2PNA A;  1BHH A;  1CWE A;  2CIA A;  3VS4 A;  1SHD A;  3VRO A;  5EEL A;  1O4D A;  2ETZ A;  2LQW A;  5EHP A;  2KNO A;  3IMJ A;  3PFV A;  4NWF A;  1HCS B;  2LNX A;  1JYQ A;  1O4J A;  3PJP A;  1O4G A;  2CI9 A;  2DVJ A;  1G83 A;  2PLE A;  1X27 A;  1QCF A;  3VS6 A;  2C9W A;  1AYD A;  1RPY A;  1SPR A;  3CD3 A;  4JEG A;  1O4O A;  3US4 A;  1A07 A;  2EU0 A;  1O46 A;  4EIH A;  3OV1 A;  3TL0 A;  3VS0 A;  3CBL A;  4P9V A;  1O4L A;  2MRK A;  5HKW A;  2DCR A;  3VGO A;  4F59 A;  4H1O A;  1Z3K A;  4D8K A;  1SKJ A;  1BFJ A;  1CSZ A;  1BLK A;  4ROJ A;  2YU7 A;  1CSY A;  1GHU A;  5DC9 A;  4DGX A;  1KA6 A;  3MXC A;  2ROR A;  2IUI A;  4JGH A;  2Y1N A;  2DLY A;  4OHI A;  1Y57 A;  2KGY A;  1FMK A;  2OZO A;  1O4C A;  2PNB A;  1CJ1 A;  1OPK A;  1O43 A;  4F5A A;  1AD5 A;  3VS2 A;  1XA6 A;  2ECD A;  3GXW A;  5D0J A;  5IBM A;  1TCE A;  2Y1M A;  1M61 A;  2CI8 A;  2EKX A;  1RJA A;  1FYR A;  2EYY A;  1LUN A;  3C7I A;  3GXX A;  3T04 A;  4X6S A;  1BKM A;  1O4N A;  1GRI A;  1RQQ C;  5AXI A;  4XZ1 A;  1KC2 A;  4U17 A;  2LCT A;  1B47 A;  1O4E A;  2EO3 A;  3VRP A;  2C0I A;  2IUG A;  3MAZ A;  4OHL A;  1I3Z A;  1A1A A;  4XZ0 A;  5DC0 B;  5IBS A;  3BUX B;  2IUH A;  1FBV A;  5BO4 A;  3HCK A;  3PQZ A;  1AYC A;  1Y1U A;  1OO4 A;  2H5K A;  1A1C A;  3CWG A;  4A4B A;  2H8H A;  2KK6 A;  3UF4 A;  1FU6 A;  2DLZ A;  2OQ1 A;  1NZL A;  3TKZ A;  1O47 A;  3VRQ A;  3IN8 A;  1BM2 A;  1ZFP E;  1O48 A;  3HHM B;  4E68 A;  3WA4 A;  1WQU A;  3IMD A;  2Y3A B;  2LNW A;  2HDV A;  1O4P A;  4M4Z A;  3UYO A;  4FL3 A;  2PLD A;  3MXY A;  1LKK A;  1SPS A;  5GJH A;  1R1Q A;  2K7A B;  1OO3 A;  2JYQ A;  4K2R A;  2CRH A;  2MQI A;  4H34 A;  1AYA A;  3PSK A;  1O4A A;  1PIC A;  1LUM A;  1A81 A;  1FU5 A;  2QMS A;  2LQN A;  5EEQ A;  4A4C A;  1AOT F;  2HCK A;  1A1B A;  3ZNI A;  3PLF B;  1M27 A;  1JYU A;  1QAD A;  5EG3 B;  1O44 A;  1R1S A;  1YVH A;  2EYV A;  3N7Y A;  1P13 A;  2PTK A;  1K9A A;  5KAZ A;  1D1Z A;  1KSW A;  2MC1 A;  4P9Z A;  2IZV A;  2SRC A;  2LRA A;  1O4I A;  1O41 A;  1LCJ A;  3M7F A;  4LUE A;  3N84 A;  3VS1 A;  4GL9 E;  3PSJ A;  2B3O A;  1QG1 E;  1IJR A;  1SHB A;  1AOU F;  2ABL A;  3BUW B;  4OHE A;  3VS3 A;  1O4R A;  1O4F A;  5DF6 A;  3VRN A;  3KFJ A;  3QWY A;  3S8L A;  3LYV A;  1H9O A;  1BHF A;  3CXL A;  5HKZ A;  1FHS A;  1O4M A;  1O4H A;  1SHA A;  2GE9 A;  3VRZ A;  1UUR A;  1O4Q A;  2HUW A;  3BUO B;  1O49 A;  2EL8 A;  2AOB A;  3S8N A;  3OP0 A;  1KA7 A;  4TZI A;  1JYR A;  1LUK A;  2MRJ A;  1X6C A;  1R1P A;  1BG1 A;  1A09 A;  2C0T A;  3IN7 A;  4L1B B;  1BMB A;  4FBN A;  1YVL A;  5J3X A;  1F2F A; 
#chains in the Genus database with same CATH homology
 1NZV A;  4WWQ A;  2K79 B;  4DGP A;  5HKY A;  4K44 A;  1AYB A;  1A1E A;  1BLJ A;  1X0N A;  1O45 A;  3VRY A;  1D4W A;  2VIF A;  3BUM B;  3OB2 B;  1IS0 A;  1LCK A;  1LUI A;  2L3T A;  2FCI A;  2HDX A;  2RSY A;  4GPL B;  2RVF A;  4QSY A;  2MK2 A;  3PS5 A;  2XP1 A;  2EYZ A;  1FBZ A;  2AOA A;  3HIZ B;  2SHP A;  3EAZ A;  2GSB A;  2EO6 A;  2YSX A;  2C0O A;  4NWG A;  4OHH A;  2CBL A;  3VRR A;  2HMH A;  5I6V A;  1BF5 A;  1A08 A;  3VS7 A;  5AUL A;  1BFI A;  1UUS A;  1AB2 A;  3VS5 A;  3QWX X;  1NRV A;  4K45 A;  2FO0 A;  5DC4 A;  4GWF A;  2DM0 A;  4FL2 A;  1MIL A;  1HCT B;  4OHD A;  3BKB A;  1JWO A;  1O4B A;  4JE4 A;  1CWD L;  3K2M A;  3S8O A;  2DX0 A;  2RMX A;  3N8M A;  1TZE E;  3BUN B;  1JU5 A;  1OPL A;  2H46 E;  2L4K A;  3S9K A;  2EOB A;  2BBU A;  5GJI A;  4U1P A;  2AUG A;  3EAC A;  1MW4 A;  3OB1 B;  1BHH B;  2CR4 A;  5EHR A;  4LUD A;  3NHN A;  5CDW A;  1BKL A;  2L6K A;  3OVE A;  4EY0 A;  1LKL A;  4K11 A;  3GQI B;  4F5B A;  1O42 A;  2CS0 A;  4E93 A;  1F1W A;  1O4K A;  1D4T A;  2PNA A;  1BHH A;  1CWE A;  2CIA A;  3VS4 A;  1SHD A;  3VRO A;  5EEL A;  1O4D A;  2ETZ A;  2LQW A;  5EHP A;  2KNO A;  3IMJ A;  3PFV A;  4NWF A;  1HCS B;  2LNX A;  1JYQ A;  1O4J A;  3PJP A;  1O4G A;  2CI9 A;  2DVJ A;  1G83 A;  2PLE A;  1X27 A;  1QCF A;  3VS6 A;  2C9W A;  1AYD A;  1RPY A;  1SPR A;  3CD3 A;  4JEG A;  1O4O A;  3US4 A;  1A07 A;  2EU0 A;  1O46 A;  4EIH A;  3OV1 A;  3TL0 A;  3VS0 A;  3CBL A;  4P9V A;  1O4L A;  2MRK A;  5HKW A;  2DCR A;  3VGO A;  4F59 A;  4H1O A;  1Z3K A;  4D8K A;  1SKJ A;  1BFJ A;  1CSZ A;  1BLK A;  4ROJ A;  2YU7 A;  1CSY A;  1GHU A;  5DC9 A;  4DGX A;  1KA6 A;  3MXC A;  2ROR A;  2IUI A;  4JGH A;  2Y1N A;  2DLY A;  4OHI A;  1Y57 A;  1FMK A;  2OZO A;  1O4C A;  2PNB A;  1CJ1 A;  1OPK A;  1O43 A;  4F5A A;  1AD5 A;  3VS2 A;  1XA6 A;  2ECD A;  3GXW A;  5D0J A;  5IBM A;  1TCE A;  2Y1M A;  1M61 A;  2CI8 A;  2EKX A;  1RJA A;  1FYR A;  2EYY A;  1LUN A;  3C7I A;  3GXX A;  3T04 A;  4X6S A;  1BKM A;  1O4N A;  1GRI A;  1RQQ C;  5AXI A;  4XZ1 A;  1KC2 A;  4U17 A;  2LCT A;  1B47 A;  1O4E A;  2EO3 A;  3VRP A;  2C0I A;  2IUG A;  3MAZ A;  4OHL A;  1I3Z A;  1A1A A;  4XZ0 A;  5DC0 B;  5IBS A;  3BUX B;  2IUH A;  1FBV A;  5BO4 A;  3HCK A;  3PQZ A;  1AYC A;  1Y1U A;  1OO4 A;  2H5K A;  1A1C A;  3CWG A;  4A4B A;  2H8H A;  2KK6 A;  3UF4 A;  1FU6 A;  2DLZ A;  2OQ1 A;  1NZL A;  3TKZ A;  1O47 A;  3VRQ A;  3IN8 A;  1BM2 A;  1ZFP E;  1O48 A;  3HHM B;  4E68 A;  3WA4 A;  1WQU A;  3IMD A;  2Y3A B;  2LNW A;  2HDV A;  1O4P A;  4M4Z A;  3UYO A;  4FL3 A;  2PLD A;  3MXY A;  1LKK A;  1SPS A;  5GJH A;  1R1Q A;  2K7A B;  1OO3 A;  2JYQ A;  4K2R A;  2CRH A;  2MQI A;  4H34 A;  1AYA A;  3PSK A;  1O4A A;  1PIC A;  1LUM A;  1A81 A;  1FU5 A;  2QMS A;  2LQN A;  5EEQ A;  4A4C A;  1AOT F;  2HCK A;  1A1B A;  3ZNI A;  3PLF B;  1M27 A;  1JYU A;  1QAD A;  5EG3 B;  1O44 A;  1R1S A;  1YVH A;  2EYV A;  3N7Y A;  1P13 A;  2PTK A;  1K9A A;  5KAZ A;  1D1Z A;  1KSW A;  2MC1 A;  4P9Z A;  2IZV A;  2SRC A;  1O4I A;  1O41 A;  1LCJ A;  3M7F A;  4LUE A;  3N84 A;  3VS1 A;  4GL9 E;  3PSJ A;  2B3O A;  1QG1 E;  1IJR A;  1SHB A;  1AOU F;  2ABL A;  3BUW B;  4OHE A;  3VS3 A;  1O4R A;  1O4F A;  5DF6 A;  3VRN A;  3KFJ A;  3QWY A;  3S8L A;  1H9O A;  1BHF A;  3CXL A;  5HKZ A;  1FHS A;  1O4M A;  1O4H A;  1SHA A;  2GE9 A;  3VRZ A;  1UUR A;  1O4Q A;  2HUW A;  3BUO B;  1O49 A;  2EL8 A;  2AOB A;  3S8N A;  3OP0 A;  1KA7 A;  4TZI A;  1JYR A;  1LUK A;  2MRJ A;  1X6C A;  1R1P A;  1BG1 A;  1A09 A;  2C0T A;  3IN7 A;  4L1B B;  1BMB A;  4FBN A;  1YVL A;  5J3X A;  1F2F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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