1O4QA

Crystal structure of sh2 in complex with ru79256.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4qA00
2Y3AB 3VRNA 3OP0A 3CXLA 4NWGA 3VROA 4JE4A 2EO6A 1AYCA 3VGOA 1KA7A 1FU6A 1MW4A 2ABLA 2IUIA 4FL2A 1CSZA 5GJHA 1G83A 1BFJA 2XP1A 3VS6A 4A4BA 1O44A 5IBSA 1O4OA 2K79B 5DC4A 1QCFA 2DLYA 5EEQA 4JEGA 1O43A 1A09A 1P13A 2RVFA 3N7YA 3VRRA 4OHLA 1X27A 2SRCA 3VRZA 1TCEA 1M61A 3HIZB 5AULA 2LCTA 4H1OA 4F5AA 3S9KA 1CSYA 3BUNB 1X0NA 2LQNA 4JGHA 2C9WA 5EHPA 3MXCA 3OB2B 3M7FA 3TKZA 1F2FA 1OPKA 2C0OA 1A81A 2RMXA 4K11A 2EYYA 3QWXX 1AYBA 3QWYA 1Y1UA 3PQZA 1R1SA 4X6SA 3VS2A 1O49A 2OZOA 3S8NA 4L1BB 4DGXA 1AYDA 3IMJA 1O4JA 2IZVA 1O48A 2RORA 4FL3A 1LCKA 3PS5A 2PLEA 3K2MA 3VRYA 2HDXA 2MC1A 1KA6A 4LUEA 4EIHA 2AUGA 5EHRA 5HKWA 1LKKA 1TZEE 3US4A 2ECDA 1KC2A 2GSBA 2K7AB 3VS3A 1A08A 1RPYA 4E93A 2Y1MA 1MILA 4M4ZA 1A07A 1JYUA 2EU0A 4GL9E 1O4FA 2B3OA 2CIAA 3PJPA 2PLDA 2LNWA 2MRKA 4K44A 4E68A 1O4EA 4OHEA 1HCSB 3KFJA 1LCJA 3NHNA 2KK6A 2MQIA 3VS7A 4FBNA 1R1PA 3PLFB 1FBZA 4TZIA 2Y1NA 1AD5A 2L3TA 1A1BA 1O4MA 1O4NA 3N8MA 5BO4A 2RSYA 1O4HA 2H5KA 3TL0A 2LQWA 1IJRA 5CDWA 1O4AA 1JWOA 1O46A 3WA4A 3S8LA 4DGPA 3VRPA 3S8OA 4ROJA 2L6KA 1AOTF 1WQUA 4WWQA 1O45A 3VRQA 3MXYA 1Y57A 2FO0A 3HHMB 2CS0A 1GRIA 1D1ZA 2HUWA 1IS0A 1HCTB 1B47A 1OO4A 1A1EA 3OB1B 3VS5A 1A1CA 4F59A 3UF4A 2VIFA 3EAZA 1FMKA 2CR4A 1BHHB 2CRHA 4U1PA 3BUXB 2ETZA 5GJIA 3IN8A 2LNXA 2SHPA 1BF5A 4H34A 1X6CA 1O4PA 1BFIA 5DC0B 3VS0A 2IUGA 1D4WA 5KAZA 1SHAA 1BHHA 4OHHA 2YSXA 1BKMA 2BBUA 1LKLA 4A4CA 1K9AA 3BUWB 4NWFA 3PFVA 1XA6A 1BM2A 1BG1A 1NZLA 4GPLB 5AXIA 1I3ZA 1JYRA 1BMBA 1FHSA 1FBVA 3VS1A 3GXXA 1PICA 3C7IA 1O4GA 2EYZA 5D0JA 2DM0A 1O4CA 1O4LA 4F5BA 5DC9A 1AB2A 2H8HA 2DX0A 2AOBA 2L4KA 1LUIA 2KNOA 3T04A 2PTKA 3N84A 4GWFA 1NZVA 2OQ1A 3UYOA 5EG3B 1KSWA 5IBMA 3GXWA 1O4IA 2EKXA 3IN7A 1O4BA 3CD3A 4K45A 1SHBA 4OHDA 1OO3A 1CJ1A 2EO3A 2PNAA 1O42A 2C0TA 1SKJA 2EOBA 3EACA 3CWGA 1JYQA 4P9ZA 1O41A 1O4QA 1SHDA 3ZNIA 1O4KA 2FCIA 4U17A 3GQIB 3OV1A 1Z3KA 3VS4A 3OVEA 4XZ0A 3PSJA 1UUSA 2EYVA 1YVHA 2AOAA 1BKLA 5I6VA 5EELA 2PNBA 2MRJA 1FYRA 1D4TA 1LUMA 5HKZA 1JU5A 1R1QA 2IUHA 4QSYA 1O47A 1BLKA 3BUOB 1QADA 1LUNA 1GHUA 1H9OA 2QMSA 1CWDL 5J3XA 1CWEA 1BLJA 3MAZA 1O4RA 4P9VA 1LUKA 2H46E 1QG1E 4D8KA 1AYAA 1SPRA 3HCKA 4XZ1A 1M27A 2CI9A 1RQQC 2DVJA 1F1WA 2GE9A 1RJAA 2CI8A 2DCRA 5DF6A 2C0IA 4LUDA 1ZFPE 3CBLA 1YVLA 2HCKA 4OHIA 1SPSA 3BUMB 3BKBA 2EL8A 1AOUF 1O4DA 5HKYA 1OPLA 3PSKA 2DLZA 1UURA 4EY0A 2JYQA 2YU7A 2MK2A 1NRVA 4K2RA 2HMHA 2CBLA 2HDVA 1A1AA 1FU5A 1BHFA 3IMDA
chains in the Genus database with same CATH superfamily
2Y3AB 3VRNA 3OP0A 3CXLA 4NWGA 3VROA 4JE4A 2EO6A 1AYCA 3VGOA 1KA7A 1FU6A 1MW4A 2ABLA 2IUIA 4FL2A 1CSZA 5GJHA 1G83A 1BFJA 2XP1A 3VS6A 4A4BA 1O44A 5IBSA 1O4OA 2K79B 5DC4A 1QCFA 2DLYA 5EEQA 4JEGA 1O43A 1A09A 1P13A 2RVFA 3N7YA 3VRRA 4OHLA 1X27A 2SRCA 3VRZA 1TCEA 1M61A 3HIZB 5AULA 2LCTA 4H1OA 4F5AA 3S9KA 1CSYA 3BUNB 1X0NA 2LQNA 4JGHA 2C9WA 5EHPA 3MXCA 3OB2B 3M7FA 3TKZA 1F2FA 1OPKA 2C0OA 1A81A 2RMXA 4K11A 2EYYA 3QWXX 1AYBA 3QWYA 1Y1UA 3PQZA 1R1SA 4X6SA 3VS2A 1O49A 2OZOA 3S8NA 4L1BB 4DGXA 1AYDA 3IMJA 1O4JA 2IZVA 1O48A 2RORA 4FL3A 1LCKA 3PS5A 2PLEA 3K2MA 3VRYA 2HDXA 2MC1A 1KA6A 4LUEA 4EIHA 2AUGA 5EHRA 5HKWA 1LKKA 1TZEE 3US4A 2ECDA 1KC2A 2GSBA 2K7AB 3VS3A 1A08A 1RPYA 4E93A 2Y1MA 1MILA 4M4ZA 1A07A 1JYUA 2EU0A 4GL9E 1O4FA 2B3OA 2CIAA 3PJPA 2PLDA 2LNWA 2MRKA 4K44A 4E68A 1O4EA 4OHEA 1HCSB 3KFJA 1LCJA 3NHNA 2KK6A 2MQIA 3VS7A 3K2TA 4FBNA 1R1PA 3PLFB 1FBZA 4TZIA 2Y1NA 1AD5A 2L3TA 1A1BA 1O4MA 1O4NA 3N8MA 5BO4A 2RSYA 1O4HA 2H5KA 3TL0A 2LQWA 1IJRA 5CDWA 1O4AA 1JWOA 1O46A 3WA4A 3S8LA 4DGPA 2KGYA 3VRPA 3S8OA 4ROJA 2L6KA 1AOTF 1WQUA 4WWQA 1O45A 3VRQA 3MXYA 1Y57A 2FO0A 3HHMB 2CS0A 1GRIA 1D1ZA 2HUWA 1IS0A 1HCTB 1B47A 1OO4A 1A1EA 3OB1B 3VS5A 1A1CA 4F59A 3UF4A 2VIFA 3EAZA 1FMKA 2CR4A 1BHHB 2CRHA 4U1PA 3BUXB 2LRAA 2ETZA 5GJIA 3IN8A 2LNXA 2SHPA 1BF5A 4H34A 1X6CA 1O4PA 1BFIA 5DC0B 3VS0A 2IUGA 1D4WA 5KAZA 1SHAA 1BHHA 4OHHA 2YSXA 1BKMA 2BBUA 1LKLA 4A4CA 1K9AA 3BUWB 4NWFA 3PFVA 1XA6A 1BM2A 1BG1A 1NZLA 4GPLB 5AXIA 1I3ZA 1JYRA 1BMBA 1FHSA 1FBVA 3VS1A 3GXXA 1PICA 3C7IA 1O4GA 2EYZA 5D0JA 2DM0A 1O4CA 1O4LA 4F5BA 5DC9A 1AB2A 2H8HA 2DX0A 2AOBA 2L4KA 1LUIA 2KNOA 3T04A 2PTKA 3N84A 4GWFA 1NZVA 2OQ1A 3UYOA 5EG3B 1KSWA 5IBMA 3GXWA 1O4IA 2EKXA 3IN7A 1O4BA 3CD3A 4K45A 1SHBA 4OHDA 1OO3A 1CJ1A 2EO3A 2PNAA 1O42A 2C0TA 1SKJA 2EOBA 3EACA 3CWGA 1JYQA 4P9ZA 1O41A 1O4QA 1SHDA 3ZNIA 1O4KA 2FCIA 4U17A 3GQIB 3OV1A 1Z3KA 3VS4A 3OVEA 4XZ0A 3PSJA 1UUSA 2EYVA 1YVHA 2AOAA 1BKLA 5I6VA 5EELA 2PNBA 2MRJA 1FYRA 1D4TA 1LUMA 5HKZA 1JU5A 1R1QA 2IUHA 4QSYA 1O47A 1BLKA 3BUOB 1QADA 1LUNA 1GHUA 1H9OA 2QMSA 1CWDL 5J3XA 1CWEA 1BLJA 3MAZA 1O4RA 4P9VA 1LUKA 2H46E 1QG1E 4D8KA 1AYAA 1SPRA 3HCKA 4XZ1A 1M27A 2CI9A 1RQQC 2DVJA 1F1WA 2GE9A 1RJAA 2CI8A 3LYVA 2DCRA 5DF6A 2C0IA 4LUDA 1ZFPE 3CBLA 1YVLA 2HCKA 4OHIA 1SPSA 3BUMB 3BKBA 2EL8A 1AOUF 1O4DA 5HKYA 1OPLA 3PSKA 2DLZA 1UURA 4EY0A 2JYQA 2YU7A 2MK2A 1NRVA 4K2RA 2HMHA 2CBLA 2HDVA 1A1AA 1FU5A 1BHFA 3IMDA
chains in the Genus database with same CATH topology
2Y3AB 3VRNA 3OP0A 3CXLA 4NWGA 3VROA 4JE4A 2EO6A 1AYCA 3VGOA 1KA7A 1FU6A 1MW4A 2ABLA 2IUIA 4FL2A 1CSZA 5GJHA 1G83A 1BFJA 2XP1A 3VS6A 4A4BA 1O44A 5IBSA 1O4OA 2K79B 5DC4A 1QCFA 2DLYA 5EEQA 4JEGA 1O43A 1A09A 1P13A 2RVFA 3N7YA 3VRRA 4OHLA 1X27A 2SRCA 3VRZA 1TCEA 1M61A 3HIZB 5AULA 2LCTA 4H1OA 4F5AA 3S9KA 1CSYA 3BUNB 1X0NA 2LQNA 4JGHA 2C9WA 5EHPA 3MXCA 3OB2B 3M7FA 3TKZA 1F2FA 1OPKA 2C0OA 1A81A 2RMXA 4K11A 2EYYA 3QWXX 1AYBA 3QWYA 1Y1UA 3PQZA 1R1SA 4X6SA 3VS2A 1O49A 2OZOA 3S8NA 4L1BB 4DGXA 1AYDA 3IMJA 1O4JA 2IZVA 1O48A 2RORA 4FL3A 1LCKA 3PS5A 2PLEA 3K2MA 3VRYA 2HDXA 2MC1A 1KA6A 4LUEA 4EIHA 2AUGA 5EHRA 5HKWA 1LKKA 1TZEE 3US4A 2ECDA 1KC2A 2GSBA 2K7AB 3VS3A 1A08A 1RPYA 4E93A 2Y1MA 1MILA 4M4ZA 1A07A 1JYUA 2EU0A 4GL9E 1O4FA 2B3OA 2CIAA 3PJPA 2PLDA 2LNWA 2MRKA 4K44A 4E68A 1O4EA 4OHEA 1HCSB 3KFJA 1LCJA 3NHNA 2KK6A 2MQIA 3VS7A 4FBNA 1R1PA 3PLFB 1FBZA 4TZIA 2Y1NA 1AD5A 2L3TA 1A1BA 1O4MA 1O4NA 3N8MA 5BO4A 2RSYA 1O4HA 2H5KA 3TL0A 2LQWA 1IJRA 5CDWA 1O4AA 1JWOA 1O46A 3WA4A 3S8LA 4DGPA 3VRPA 3S8OA 4ROJA 2L6KA 1AOTF 1WQUA 4WWQA 1O45A 3VRQA 3MXYA 1Y57A 2FO0A 3HHMB 2CS0A 1GRIA 1D1ZA 2HUWA 1IS0A 1HCTB 1B47A 1OO4A 1A1EA 3OB1B 3VS5A 1A1CA 4F59A 3UF4A 2VIFA 3EAZA 1FMKA 2CR4A 1BHHB 2CRHA 4U1PA 3BUXB 2ETZA 5GJIA 3IN8A 2LNXA 2SHPA 1BF5A 4H34A 1X6CA 1O4PA 1BFIA 5DC0B 3VS0A 2IUGA 1D4WA 5KAZA 1SHAA 1BHHA 4OHHA 2YSXA 1BKMA 2BBUA 1LKLA 4A4CA 1K9AA 3BUWB 4NWFA 3PFVA 1XA6A 1BM2A 1BG1A 1NZLA 4GPLB 5AXIA 1I3ZA 1JYRA 1BMBA 1FHSA 1FBVA 3VS1A 3GXXA 1PICA 3C7IA 1O4GA 2EYZA 5D0JA 2DM0A 1O4CA 1O4LA 4F5BA 5DC9A 1AB2A 2H8HA 2DX0A 2AOBA 2L4KA 1LUIA 2KNOA 3T04A 2PTKA 3N84A 4GWFA 1NZVA 2OQ1A 3UYOA 5EG3B 1KSWA 5IBMA 3GXWA 1O4IA 2EKXA 3IN7A 1O4BA 3CD3A 4K45A 1SHBA 4OHDA 1OO3A 1CJ1A 2EO3A 2PNAA 1O42A 2C0TA 1SKJA 2EOBA 3EACA 3CWGA 1JYQA 4P9ZA 1O41A 1O4QA 1SHDA 3ZNIA 1O4KA 2FCIA 4U17A 3GQIB 3OV1A 1Z3KA 3VS4A 3OVEA 4XZ0A 3PSJA 1UUSA 2EYVA 1YVHA 2AOAA 1BKLA 5I6VA 5EELA 2PNBA 2MRJA 1FYRA 1D4TA 1LUMA 5HKZA 1JU5A 1R1QA 2IUHA 4QSYA 1O47A 1BLKA 3BUOB 1QADA 1LUNA 1GHUA 1H9OA 2QMSA 1CWDL 5J3XA 1CWEA 1BLJA 3MAZA 1O4RA 4P9VA 1LUKA 2H46E 1QG1E 4D8KA 1AYAA 1SPRA 3HCKA 4XZ1A 1M27A 2CI9A 1RQQC 2DVJA 1F1WA 2GE9A 1RJAA 2CI8A 2DCRA 5DF6A 2C0IA 4LUDA 1ZFPE 3CBLA 1YVLA 2HCKA 4OHIA 1SPSA 3BUMB 3BKBA 2EL8A 1AOUF 1O4DA 5HKYA 1OPLA 3PSKA 2DLZA 1UURA 4EY0A 2JYQA 2YU7A 2MK2A 1NRVA 4K2RA 2HMHA 2CBLA 2HDVA 1A1AA 1FU5A 1BHFA 3IMDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y3A B;  3VRN A;  3OP0 A;  3CXL A;  4NWG A;  3VRO A;  4JE4 A;  2EO6 A;  1AYC A;  3VGO A;  1KA7 A;  1FU6 A;  1MW4 A;  2ABL A;  2IUI A;  4FL2 A;  1CSZ A;  5GJH A;  1G83 A;  1BFJ A;  2XP1 A;  3VS6 A;  4A4B A;  1O44 A;  5IBS A;  1O4O A;  2K79 B;  5DC4 A;  1QCF A;  2DLY A;  5EEQ A;  4JEG A;  1O43 A;  1A09 A;  1P13 A;  2RVF A;  3N7Y A;  3VRR A;  4OHL A;  1X27 A;  2SRC A;  3VRZ A;  1TCE A;  1M61 A;  3HIZ B;  5AUL A;  2LCT A;  4H1O A;  4F5A A;  3S9K A;  1CSY A;  3BUN B;  1X0N A;  2LQN A;  4JGH A;  2C9W A;  5EHP A;  3MXC A;  3OB2 B;  3M7F A;  3TKZ A;  1F2F A;  1OPK A;  2C0O A;  1A81 A;  2RMX A;  4K11 A;  2EYY A;  3QWX X;  1AYB A;  3QWY A;  1Y1U A;  3PQZ A;  1R1S A;  4X6S A;  3VS2 A;  1O49 A;  2OZO A;  3S8N A;  4L1B B;  4DGX A;  1AYD A;  3IMJ A;  1O4J A;  2IZV A;  1O48 A;  2ROR A;  4FL3 A;  1LCK A;  3PS5 A;  2PLE A;  3K2M A;  3VRY A;  2HDX A;  2MC1 A;  1KA6 A;  4LUE A;  4EIH A;  2AUG A;  5EHR A;  5HKW A;  1LKK A;  1TZE E;  3US4 A;  2ECD A;  1KC2 A;  2GSB A;  2K7A B;  3VS3 A;  1A08 A;  1RPY A;  4E93 A;  2Y1M A;  1MIL A;  4M4Z A;  1A07 A;  1JYU A;  2EU0 A;  4GL9 E;  1O4F A;  2B3O A;  2CIA A;  3PJP A;  2PLD A;  2LNW A;  2MRK A;  4K44 A;  4E68 A;  1O4E A;  4OHE A;  1HCS B;  3KFJ A;  1LCJ A;  3NHN A;  2KK6 A;  2MQI A;  3VS7 A;  4FBN A;  1R1P A;  3PLF B;  1FBZ A;  4TZI A;  2Y1N A;  1AD5 A;  2L3T A;  1A1B A;  1O4M A;  1O4N A;  3N8M A;  5BO4 A;  2RSY A;  1O4H A;  2H5K A;  3TL0 A;  2LQW A;  1IJR A;  5CDW A;  1O4A A;  1JWO A;  1O46 A;  3WA4 A;  3S8L A;  4DGP A;  3VRP A;  3S8O A;  4ROJ A;  2L6K A;  1AOT F;  1WQU A;  4WWQ A;  1O45 A;  3VRQ A;  3MXY A;  1Y57 A;  2FO0 A;  3HHM B;  2CS0 A;  1GRI A;  1D1Z A;  2HUW A;  1IS0 A;  1HCT B;  1B47 A;  1OO4 A;  1A1E A;  3OB1 B;  3VS5 A;  1A1C A;  4F59 A;  3UF4 A;  2VIF A;  3EAZ A;  1FMK A;  2CR4 A;  1BHH B;  2CRH A;  4U1P A;  3BUX B;  2ETZ A;  5GJI A;  3IN8 A;  2LNX A;  2SHP A;  1BF5 A;  4H34 A;  1X6C A;  1O4P A;  1BFI A;  5DC0 B;  3VS0 A;  2IUG A;  1D4W A;  5KAZ A;  1SHA A;  1BHH A;  4OHH A;  2YSX A;  1BKM A;  2BBU A;  1LKL A;  4A4C A;  1K9A A;  3BUW B;  4NWF A;  3PFV A;  1XA6 A;  1BM2 A;  1BG1 A;  1NZL A;  4GPL B;  5AXI A;  1I3Z A;  1JYR A;  1BMB A;  1FHS A;  1FBV A;  3VS1 A;  3GXX A;  1PIC A;  3C7I A;  1O4G A;  2EYZ A;  5D0J A;  2DM0 A;  1O4C A;  1O4L A;  4F5B A;  5DC9 A;  1AB2 A;  2H8H A;  2DX0 A;  2AOB A;  2L4K A;  1LUI A;  2KNO A;  3T04 A;  2PTK A;  3N84 A;  4GWF A;  1NZV A;  2OQ1 A;  3UYO A;  5EG3 B;  1KSW A;  5IBM A;  3GXW A;  1O4I A;  2EKX A;  3IN7 A;  1O4B A;  3CD3 A;  4K45 A;  1SHB A;  4OHD A;  1OO3 A;  1CJ1 A;  2EO3 A;  2PNA A;  1O42 A;  2C0T A;  1SKJ A;  2EOB A;  3EAC A;  3CWG A;  1JYQ A;  4P9Z A;  1O41 A;  1O4Q A;  1SHD A;  3ZNI A;  1O4K A;  2FCI A;  4U17 A;  3GQI B;  3OV1 A;  1Z3K A;  3VS4 A;  3OVE A;  4XZ0 A;  3PSJ A;  1UUS A;  2EYV A;  1YVH A;  2AOA A;  1BKL A;  5I6V A;  5EEL A;  2PNB A;  2MRJ A;  1FYR A;  1D4T A;  1LUM A;  5HKZ A;  1JU5 A;  1R1Q A;  2IUH A;  4QSY A;  1O47 A;  1BLK A;  3BUO B;  1QAD A;  1LUN A;  1GHU A;  1H9O A;  2QMS A;  1CWD L;  5J3X A;  1CWE A;  1BLJ A;  3MAZ A;  1O4R A;  4P9V A;  1LUK A;  2H46 E;  1QG1 E;  4D8K A;  1AYA A;  1SPR A;  3HCK A;  4XZ1 A;  1M27 A;  2CI9 A;  1RQQ C;  2DVJ A;  1F1W A;  2GE9 A;  1RJA A;  2CI8 A;  2DCR A;  5DF6 A;  2C0I A;  4LUD A;  1ZFP E;  3CBL A;  1YVL A;  2HCK A;  4OHI A;  1SPS A;  3BUM B;  3BKB A;  2EL8 A;  1AOU F;  1O4D A;  5HKY A;  1OPL A;  3PSK A;  2DLZ A;  1UUR A;  4EY0 A;  2JYQ A;  2YU7 A;  2MK2 A;  1NRV A;  4K2R A;  2HMH A;  2CBL A;  2HDV A;  1A1A A;  1FU5 A;  1BHF A;  3IMD A; 
#chains in the Genus database with same CATH topology
 2Y3A B;  3VRN A;  3OP0 A;  3CXL A;  4NWG A;  3VRO A;  4JE4 A;  2EO6 A;  1AYC A;  3VGO A;  1KA7 A;  1FU6 A;  1MW4 A;  2ABL A;  2IUI A;  4FL2 A;  1CSZ A;  5GJH A;  1G83 A;  1BFJ A;  2XP1 A;  3VS6 A;  4A4B A;  1O44 A;  5IBS A;  1O4O A;  2K79 B;  5DC4 A;  1QCF A;  2DLY A;  5EEQ A;  4JEG A;  1O43 A;  1A09 A;  1P13 A;  2RVF A;  3N7Y A;  3VRR A;  4OHL A;  1X27 A;  2SRC A;  3VRZ A;  1TCE A;  1M61 A;  3HIZ B;  5AUL A;  2LCT A;  4H1O A;  4F5A A;  3S9K A;  1CSY A;  3BUN B;  1X0N A;  2LQN A;  4JGH A;  2C9W A;  5EHP A;  3MXC A;  3OB2 B;  3M7F A;  3TKZ A;  1F2F A;  1OPK A;  2C0O A;  1A81 A;  2RMX A;  4K11 A;  2EYY A;  3QWX X;  1AYB A;  3QWY A;  1Y1U A;  3PQZ A;  1R1S A;  4X6S A;  3VS2 A;  1O49 A;  2OZO A;  3S8N A;  4L1B B;  4DGX A;  1AYD A;  3IMJ A;  1O4J A;  2IZV A;  1O48 A;  2ROR A;  4FL3 A;  1LCK A;  3PS5 A;  2PLE A;  3K2M A;  3VRY A;  2HDX A;  2MC1 A;  1KA6 A;  4LUE A;  4EIH A;  2AUG A;  5EHR A;  5HKW A;  1LKK A;  1TZE E;  3US4 A;  2ECD A;  1KC2 A;  2GSB A;  2K7A B;  3VS3 A;  1A08 A;  1RPY A;  4E93 A;  2Y1M A;  1MIL A;  4M4Z A;  1A07 A;  1JYU A;  2EU0 A;  4GL9 E;  1O4F A;  2B3O A;  2CIA A;  3PJP A;  2PLD A;  2LNW A;  2MRK A;  4K44 A;  4E68 A;  1O4E A;  4OHE A;  1HCS B;  3KFJ A;  1LCJ A;  3NHN A;  2KK6 A;  2MQI A;  3VS7 A;  3K2T A;  4FBN A;  1R1P A;  3PLF B;  1FBZ A;  4TZI A;  2Y1N A;  1AD5 A;  2L3T A;  1A1B A;  1O4M A;  1O4N A;  3N8M A;  5BO4 A;  2RSY A;  1O4H A;  2H5K A;  3TL0 A;  2LQW A;  1IJR A;  5CDW A;  1O4A A;  1JWO A;  1O46 A;  3WA4 A;  3S8L A;  4DGP A;  2KGY A;  3VRP A;  3S8O A;  4ROJ A;  2L6K A;  1AOT F;  1WQU A;  4WWQ A;  1O45 A;  3VRQ A;  3MXY A;  1Y57 A;  2FO0 A;  3HHM B;  2CS0 A;  1GRI A;  1D1Z A;  2HUW A;  1IS0 A;  1HCT B;  1B47 A;  1OO4 A;  1A1E A;  3OB1 B;  3VS5 A;  1A1C A;  4F59 A;  3UF4 A;  2VIF A;  3EAZ A;  1FMK A;  2CR4 A;  1BHH B;  2CRH A;  4U1P A;  3BUX B;  2LRA A;  2ETZ A;  5GJI A;  3IN8 A;  2LNX A;  2SHP A;  1BF5 A;  4H34 A;  1X6C A;  1O4P A;  1BFI A;  5DC0 B;  3VS0 A;  2IUG A;  1D4W A;  5KAZ A;  1SHA A;  1BHH A;  4OHH A;  2YSX A;  1BKM A;  2BBU A;  1LKL A;  4A4C A;  1K9A A;  3BUW B;  4NWF A;  3PFV A;  1XA6 A;  1BM2 A;  1BG1 A;  1NZL A;  4GPL B;  5AXI A;  1I3Z A;  1JYR A;  1BMB A;  1FHS A;  1FBV A;  3VS1 A;  3GXX A;  1PIC A;  3C7I A;  1O4G A;  2EYZ A;  5D0J A;  2DM0 A;  1O4C A;  1O4L A;  4F5B A;  5DC9 A;  1AB2 A;  2H8H A;  2DX0 A;  2AOB A;  2L4K A;  1LUI A;  2KNO A;  3T04 A;  2PTK A;  3N84 A;  4GWF A;  1NZV A;  2OQ1 A;  3UYO A;  5EG3 B;  1KSW A;  5IBM A;  3GXW A;  1O4I A;  2EKX A;  3IN7 A;  1O4B A;  3CD3 A;  4K45 A;  1SHB A;  4OHD A;  1OO3 A;  1CJ1 A;  2EO3 A;  2PNA A;  1O42 A;  2C0T A;  1SKJ A;  2EOB A;  3EAC A;  3CWG A;  1JYQ A;  4P9Z A;  1O41 A;  1O4Q A;  1SHD A;  3ZNI A;  1O4K A;  2FCI A;  4U17 A;  3GQI B;  3OV1 A;  1Z3K A;  3VS4 A;  3OVE A;  4XZ0 A;  3PSJ A;  1UUS A;  2EYV A;  1YVH A;  2AOA A;  1BKL A;  5I6V A;  5EEL A;  2PNB A;  2MRJ A;  1FYR A;  1D4T A;  1LUM A;  5HKZ A;  1JU5 A;  1R1Q A;  2IUH A;  4QSY A;  1O47 A;  1BLK A;  3BUO B;  1QAD A;  1LUN A;  1GHU A;  1H9O A;  2QMS A;  1CWD L;  5J3X A;  1CWE A;  1BLJ A;  3MAZ A;  1O4R A;  4P9V A;  1LUK A;  2H46 E;  1QG1 E;  4D8K A;  1AYA A;  1SPR A;  3HCK A;  4XZ1 A;  1M27 A;  2CI9 A;  1RQQ C;  2DVJ A;  1F1W A;  2GE9 A;  1RJA A;  2CI8 A;  3LYV A;  2DCR A;  5DF6 A;  2C0I A;  4LUD A;  1ZFP E;  3CBL A;  1YVL A;  2HCK A;  4OHI A;  1SPS A;  3BUM B;  3BKB A;  2EL8 A;  1AOU F;  1O4D A;  5HKY A;  1OPL A;  3PSK A;  2DLZ A;  1UUR A;  4EY0 A;  2JYQ A;  2YU7 A;  2MK2 A;  1NRV A;  4K2R A;  2HMH A;  2CBL A;  2HDV A;  1A1A A;  1FU5 A;  1BHF A;  3IMD A; 
#chains in the Genus database with same CATH homology
 2Y3A B;  3VRN A;  3OP0 A;  3CXL A;  4NWG A;  3VRO A;  4JE4 A;  2EO6 A;  1AYC A;  3VGO A;  1KA7 A;  1FU6 A;  1MW4 A;  2ABL A;  2IUI A;  4FL2 A;  1CSZ A;  5GJH A;  1G83 A;  1BFJ A;  2XP1 A;  3VS6 A;  4A4B A;  1O44 A;  5IBS A;  1O4O A;  2K79 B;  5DC4 A;  1QCF A;  2DLY A;  5EEQ A;  4JEG A;  1O43 A;  1A09 A;  1P13 A;  2RVF A;  3N7Y A;  3VRR A;  4OHL A;  1X27 A;  2SRC A;  3VRZ A;  1TCE A;  1M61 A;  3HIZ B;  5AUL A;  2LCT A;  4H1O A;  4F5A A;  3S9K A;  1CSY A;  3BUN B;  1X0N A;  2LQN A;  4JGH A;  2C9W A;  5EHP A;  3MXC A;  3OB2 B;  3M7F A;  3TKZ A;  1F2F A;  1OPK A;  2C0O A;  1A81 A;  2RMX A;  4K11 A;  2EYY A;  3QWX X;  1AYB A;  3QWY A;  1Y1U A;  3PQZ A;  1R1S A;  4X6S A;  3VS2 A;  1O49 A;  2OZO A;  3S8N A;  4L1B B;  4DGX A;  1AYD A;  3IMJ A;  1O4J A;  2IZV A;  1O48 A;  2ROR A;  4FL3 A;  1LCK A;  3PS5 A;  2PLE A;  3K2M A;  3VRY A;  2HDX A;  2MC1 A;  1KA6 A;  4LUE A;  4EIH A;  2AUG A;  5EHR A;  5HKW A;  1LKK A;  1TZE E;  3US4 A;  2ECD A;  1KC2 A;  2GSB A;  2K7A B;  3VS3 A;  1A08 A;  1RPY A;  4E93 A;  2Y1M A;  1MIL A;  4M4Z A;  1A07 A;  1JYU A;  2EU0 A;  4GL9 E;  1O4F A;  2B3O A;  2CIA A;  3PJP A;  2PLD A;  2LNW A;  2MRK A;  4K44 A;  4E68 A;  1O4E A;  4OHE A;  1HCS B;  3KFJ A;  1LCJ A;  3NHN A;  2KK6 A;  2MQI A;  3VS7 A;  4FBN A;  1R1P A;  3PLF B;  1FBZ A;  4TZI A;  2Y1N A;  1AD5 A;  2L3T A;  1A1B A;  1O4M A;  1O4N A;  3N8M A;  5BO4 A;  2RSY A;  1O4H A;  2H5K A;  3TL0 A;  2LQW A;  1IJR A;  5CDW A;  1O4A A;  1JWO A;  1O46 A;  3WA4 A;  3S8L A;  4DGP A;  3VRP A;  3S8O A;  4ROJ A;  2L6K A;  1AOT F;  1WQU A;  4WWQ A;  1O45 A;  3VRQ A;  3MXY A;  1Y57 A;  2FO0 A;  3HHM B;  2CS0 A;  1GRI A;  1D1Z A;  2HUW A;  1IS0 A;  1HCT B;  1B47 A;  1OO4 A;  1A1E A;  3OB1 B;  3VS5 A;  1A1C A;  4F59 A;  3UF4 A;  2VIF A;  3EAZ A;  1FMK A;  2CR4 A;  1BHH B;  2CRH A;  4U1P A;  3BUX B;  2ETZ A;  5GJI A;  3IN8 A;  2LNX A;  2SHP A;  1BF5 A;  4H34 A;  1X6C A;  1O4P A;  1BFI A;  5DC0 B;  3VS0 A;  2IUG A;  1D4W A;  5KAZ A;  1SHA A;  1BHH A;  4OHH A;  2YSX A;  1BKM A;  2BBU A;  1LKL A;  4A4C A;  1K9A A;  3BUW B;  4NWF A;  3PFV A;  1XA6 A;  1BM2 A;  1BG1 A;  1NZL A;  4GPL B;  5AXI A;  1I3Z A;  1JYR A;  1BMB A;  1FHS A;  1FBV A;  3VS1 A;  3GXX A;  1PIC A;  3C7I A;  1O4G A;  2EYZ A;  5D0J A;  2DM0 A;  1O4C A;  1O4L A;  4F5B A;  5DC9 A;  1AB2 A;  2H8H A;  2DX0 A;  2AOB A;  2L4K A;  1LUI A;  2KNO A;  3T04 A;  2PTK A;  3N84 A;  4GWF A;  1NZV A;  2OQ1 A;  3UYO A;  5EG3 B;  1KSW A;  5IBM A;  3GXW A;  1O4I A;  2EKX A;  3IN7 A;  1O4B A;  3CD3 A;  4K45 A;  1SHB A;  4OHD A;  1OO3 A;  1CJ1 A;  2EO3 A;  2PNA A;  1O42 A;  2C0T A;  1SKJ A;  2EOB A;  3EAC A;  3CWG A;  1JYQ A;  4P9Z A;  1O41 A;  1O4Q A;  1SHD A;  3ZNI A;  1O4K A;  2FCI A;  4U17 A;  3GQI B;  3OV1 A;  1Z3K A;  3VS4 A;  3OVE A;  4XZ0 A;  3PSJ A;  1UUS A;  2EYV A;  1YVH A;  2AOA A;  1BKL A;  5I6V A;  5EEL A;  2PNB A;  2MRJ A;  1FYR A;  1D4T A;  1LUM A;  5HKZ A;  1JU5 A;  1R1Q A;  2IUH A;  4QSY A;  1O47 A;  1BLK A;  3BUO B;  1QAD A;  1LUN A;  1GHU A;  1H9O A;  2QMS A;  1CWD L;  5J3X A;  1CWE A;  1BLJ A;  3MAZ A;  1O4R A;  4P9V A;  1LUK A;  2H46 E;  1QG1 E;  4D8K A;  1AYA A;  1SPR A;  3HCK A;  4XZ1 A;  1M27 A;  2CI9 A;  1RQQ C;  2DVJ A;  1F1W A;  2GE9 A;  1RJA A;  2CI8 A;  2DCR A;  5DF6 A;  2C0I A;  4LUD A;  1ZFP E;  3CBL A;  1YVL A;  2HCK A;  4OHI A;  1SPS A;  3BUM B;  3BKB A;  2EL8 A;  1AOU F;  1O4D A;  5HKY A;  1OPL A;  3PSK A;  2DLZ A;  1UUR A;  4EY0 A;  2JYQ A;  2YU7 A;  2MK2 A;  1NRV A;  4K2R A;  2HMH A;  2CBL A;  2HDV A;  1A1A A;  1FU5 A;  1BHF A;  3IMD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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