5CDWA

Crystal structure analysis of a mutant grb2 sh2 domain (w121g) with a pyvnv peptide
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
98
structure length
98
Chain Sequence
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLGVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 16
structure length 98
sequence length 98
chains with identical sequence B, C, E, G, H, K, L, O, P, U, V, Y, Z, c, d
ec nomenclature
pdb deposition date 2015-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5cdwA00
4H34A 4JEGA 1LUNA 2AOAA 2HCKA 2RSYA 2RVFA 3VRRA 3VS0A 3IN8A 3GQIB 3VRYA 2EOBA 1A1BA 2EO3A 5HKZA 2EO6A 3C7IA 1TCEA 3BUOB 1Y57A 5IBSA 2MRKA 4A4BA 2DX0A 1RJAA 1G83A 2PTKA 3N84A 2C0OA 2K79B 1LUKA 2DM0A 2RORA 1BHFA 1Y1UA 1BG1A 4P9ZA 1O4JA 1NZLA 5EG3B 1OO3A 3OV1A 1LUMA 4A4CA 4OHDA 5AXIA 2LQNA 1KSWA 4K45A 5EEQA 3UF4A 3VS1A 3T04A 1BFJA 2Y1NA 4X6SA 1A1CA 1K9AA 5AULA 2H8HA 2MRJA 3S8LA 5BO4A 1IS0A 1A08A 5DC4A 2IUGA 1BF5A 1BHHB 1O4AA 3PS5A 1KA7A 3EAZA 3BUWB 3HHMB 1O4BA 1D4WA 1FU5A 3K2MA 1FBVA 3HIZB 3IN7A 3CBLA 1O44A 2EYYA 1NRVA 3PSKA 3MAZA 5KAZA 1A09A 2CRHA 2EKXA 1BLJA 2ETZA 2Y1MA 1QCFA 1D4TA 3EACA 4DGPA 4F5BA 4K2RA 5HKWA 1SPSA 1RPYA 2C9WA 1M27A 2YU7A 2H46E 4L1BB 3VGOA 2K7AB 3VS6A 2KNOA 1O43A 5DC9A 2IZVA 2LCTA 1FU6A 2Y3AB 2PLDA 1A81A 3MXCA 1GHUA 1A07A 2PLEA 4EY0A 1O4IA 4OHIA 1AD5A 2LNWA 1YVLA 2CS0A 2EL8A 5EHRA 3NHNA 1MILA 2DVJA 1FBZA 1JU5A 2DCRA 2SHPA 1BMBA 2MQIA 1GRIA 2OZOA 3BUXB 1SKJA 1X0NA 1JYUA 4GL9E 4GWFA 1CJ1A 1O4CA 1WQUA 1I3ZA 3QWYA 1B47A 2DLYA 2SRCA 4OHHA 4OHEA 4QSYA 1AYCA 3PQZA 1LCKA 2L3TA 1O4FA 2H5KA 4F59A 2XP1A 1O4NA 3CD3A 4LUDA 3BUMB 3M7FA 1BFIA 1X6CA 5HKYA 3QWXX 3US4A 1O48A 2EU0A 5EHPA 1AYDA 1OO4A 1BKLA 2LNXA 1O45A 3HCKA 1HCTB 3TKZA 5GJIA 4JGHA 3VROA 1O4OA 3N8MA 3WA4A 3IMDA 2CR4A 3ZNIA 1SHDA 5CDWA 4JE4A 3OB1B 3KFJA 4ROJA 1SHAA 5EELA 2HDVA 1O4HA 2HDXA 1FHSA 2MC1A 1F2FA 2YSXA 1JYQA 1HCSB 3GXXA 2FO0A 4EIHA 1UUSA 3CWGA 4FBNA 1O4QA 3TL0A 2PNAA 2LQWA 1O46A 3BUNB 5DF6A 4FL3A 5DC0B 2IUIA 4WWQA 3VS4A 2BBUA 4F5AA 1A1AA 1O4PA 3S9KA 1FYRA 4K44A 2CIAA 1BKMA 1H9OA 2L4KA 1O42A 5D0JA 2DLZA 1R1PA 2JYQA 4FL2A 4NWGA 2HMHA 2KK6A 1SHBA 1AYAA 3MXYA 1O4GA 1O41A 4E68A 1SPRA 1O49A 3S8NA 1O4KA 1M61A 2RMXA 2AUGA 1AOTF 4H1OA 2ECDA 1CWDL 3VRQA 3OB2B 3PLFB 3OP0A 2CI8A 2MK2A 1OPLA 3VRPA 4D8KA 1O4DA 1D1ZA 1UURA 5IBMA 1BM2A 2ABLA 1AOUF 1PICA 3N7YA 4XZ1A 3VS5A 1AB2A 3VRZA 1LKLA 1BHHA 2C0IA 1A1EA 2PNBA 3GXWA 3PSJA 2HUWA 3VS3A 1JYRA 2QMSA 4XZ0A 3PJPA 1O4EA 4GPLB 3BKBA 5I6VA 4U17A 1R1SA 2OQ1A 3OVEA 1F1WA 4OHLA 3VRNA 4U1PA 4LUEA 1JWOA 3PFVA 4E93A 4NWFA 2CI9A 1TZEE 1CSZA 1QADA 1Z3KA 3VS2A 2IUHA 1P13A 1XA6A 2FCIA 3S8OA 3UYOA 1R1QA 1RQQC 1ZFPE 1OPKA 1AYBA 4TZIA 4P9VA 1CWEA 1NZVA 2L6KA 1IJRA 2VIFA 5J3XA 2GE9A 4M4ZA 3VS7A 1O4RA 4K11A 1KA6A 2B3OA 1MW4A 2EYZA 1FMKA 1BLKA 1O4MA 1O47A 1LKKA 1LUIA 2C0TA 2AOBA 1YVHA 1LCJA 1O4LA 2CBLA 2GSBA 3CXLA 1KC2A 1QG1E 4DGXA 1CSYA 5GJHA 2EYVA 1X27A 3IMJA
chains in the Genus database with same CATH superfamily
4H34A 4JEGA 1LUNA 2AOAA 2HCKA 2RSYA 2RVFA 3VRRA 3VS0A 3IN8A 3GQIB 3VRYA 2EOBA 1A1BA 2EO3A 5HKZA 2EO6A 3C7IA 1TCEA 3BUOB 1Y57A 5IBSA 2MRKA 4A4BA 2DX0A 1RJAA 1G83A 2PTKA 3N84A 2C0OA 2K79B 1LUKA 2DM0A 2RORA 1BHFA 1Y1UA 1BG1A 4P9ZA 1O4JA 1NZLA 5EG3B 1OO3A 3OV1A 1LUMA 4A4CA 4OHDA 5AXIA 2LQNA 1KSWA 4K45A 5EEQA 3UF4A 3VS1A 3T04A 1BFJA 2Y1NA 4X6SA 1A1CA 1K9AA 5AULA 2H8HA 2MRJA 3S8LA 5BO4A 1IS0A 1A08A 5DC4A 2IUGA 1BF5A 1BHHB 1O4AA 3PS5A 1KA7A 3EAZA 3BUWB 3HHMB 1O4BA 1D4WA 1FU5A 3K2MA 1FBVA 3HIZB 3IN7A 3CBLA 1O44A 2EYYA 1NRVA 3PSKA 3MAZA 5KAZA 1A09A 2CRHA 2EKXA 1BLJA 2ETZA 2Y1MA 1QCFA 1D4TA 3EACA 4DGPA 4F5BA 4K2RA 5HKWA 1SPSA 1RPYA 2C9WA 1M27A 2YU7A 2H46E 4L1BB 3VGOA 2K7AB 3VS6A 2KNOA 1O43A 5DC9A 2IZVA 2LCTA 1FU6A 2Y3AB 2PLDA 1A81A 3MXCA 1GHUA 1A07A 2PLEA 4EY0A 1O4IA 4OHIA 1AD5A 2LNWA 1YVLA 2CS0A 2EL8A 5EHRA 3NHNA 1MILA 3K2TA 2DVJA 1FBZA 1JU5A 2DCRA 2SHPA 1BMBA 2MQIA 1GRIA 2OZOA 3BUXB 1SKJA 1X0NA 1JYUA 4GL9E 4GWFA 1CJ1A 1O4CA 1WQUA 1I3ZA 3QWYA 1B47A 2DLYA 2SRCA 4OHHA 4OHEA 4QSYA 1AYCA 3PQZA 1LCKA 2L3TA 1O4FA 2H5KA 4F59A 2XP1A 1O4NA 3CD3A 4LUDA 3BUMB 3M7FA 1BFIA 1X6CA 5HKYA 3QWXX 3US4A 1O48A 2EU0A 5EHPA 1AYDA 1OO4A 1BKLA 2LNXA 1O45A 3HCKA 2LRAA 3LYVA 1HCTB 3TKZA 5GJIA 4JGHA 3VROA 1O4OA 3N8MA 3WA4A 3IMDA 2CR4A 3ZNIA 1SHDA 5CDWA 4JE4A 3OB1B 3KFJA 4ROJA 1SHAA 5EELA 2HDVA 1O4HA 2HDXA 1FHSA 2MC1A 1F2FA 2YSXA 1JYQA 1HCSB 3GXXA 2FO0A 4EIHA 1UUSA 2KGYA 3CWGA 4FBNA 1O4QA 3TL0A 2PNAA 2LQWA 1O46A 3BUNB 5DF6A 4FL3A 5DC0B 2IUIA 4WWQA 3VS4A 2BBUA 4F5AA 1A1AA 1O4PA 3S9KA 1FYRA 4K44A 2CIAA 1BKMA 1H9OA 2L4KA 1O42A 5D0JA 2DLZA 1R1PA 2JYQA 4FL2A 4NWGA 2HMHA 2KK6A 1SHBA 1AYAA 3MXYA 1O4GA 1O41A 4E68A 1SPRA 1O49A 3S8NA 1O4KA 1M61A 2RMXA 2AUGA 1AOTF 4H1OA 2ECDA 1CWDL 3VRQA 3OB2B 3PLFB 3OP0A 2CI8A 2MK2A 1OPLA 3VRPA 4D8KA 1O4DA 1D1ZA 1UURA 5IBMA 1BM2A 2ABLA 1AOUF 1PICA 3N7YA 4XZ1A 3VS5A 1AB2A 3VRZA 1LKLA 1BHHA 2C0IA 1A1EA 2PNBA 3GXWA 3PSJA 2HUWA 3VS3A 1JYRA 2QMSA 4XZ0A 3PJPA 1O4EA 4GPLB 3BKBA 5I6VA 4U17A 1R1SA 2OQ1A 3OVEA 1F1WA 4OHLA 3VRNA 4U1PA 4LUEA 1JWOA 3PFVA 4E93A 4NWFA 2CI9A 1TZEE 1CSZA 1QADA 1Z3KA 3VS2A 2IUHA 1P13A 1XA6A 2FCIA 3S8OA 3UYOA 1R1QA 1RQQC 1ZFPE 1OPKA 1AYBA 4TZIA 4P9VA 1CWEA 1NZVA 2L6KA 1IJRA 2VIFA 5J3XA 2GE9A 4M4ZA 3VS7A 1O4RA 4K11A 1KA6A 2B3OA 1MW4A 2EYZA 1FMKA 1BLKA 1O4MA 1O47A 1LKKA 1LUIA 2C0TA 2AOBA 1YVHA 1LCJA 1O4LA 2CBLA 2GSBA 3CXLA 1KC2A 1QG1E 4DGXA 1CSYA 5GJHA 2EYVA 1X27A 3IMJA
chains in the Genus database with same CATH topology
4H34A 4JEGA 1LUNA 2AOAA 2HCKA 2RSYA 2RVFA 3VRRA 3VS0A 3IN8A 3GQIB 3VRYA 2EOBA 1A1BA 2EO3A 5HKZA 2EO6A 3C7IA 1TCEA 3BUOB 1Y57A 5IBSA 2MRKA 4A4BA 2DX0A 1RJAA 1G83A 2PTKA 3N84A 2C0OA 2K79B 1LUKA 2DM0A 2RORA 1BHFA 1Y1UA 1BG1A 4P9ZA 1O4JA 1NZLA 5EG3B 1OO3A 3OV1A 1LUMA 4A4CA 4OHDA 5AXIA 2LQNA 1KSWA 4K45A 5EEQA 3UF4A 3VS1A 3T04A 1BFJA 2Y1NA 4X6SA 1A1CA 1K9AA 5AULA 2H8HA 2MRJA 3S8LA 5BO4A 1IS0A 1A08A 5DC4A 2IUGA 1BF5A 1BHHB 1O4AA 3PS5A 1KA7A 3EAZA 3BUWB 3HHMB 1O4BA 1D4WA 1FU5A 3K2MA 1FBVA 3HIZB 3IN7A 3CBLA 1O44A 2EYYA 1NRVA 3PSKA 3MAZA 5KAZA 1A09A 2CRHA 2EKXA 1BLJA 2ETZA 2Y1MA 1QCFA 1D4TA 3EACA 4DGPA 4F5BA 4K2RA 5HKWA 1SPSA 1RPYA 2C9WA 1M27A 2YU7A 2H46E 4L1BB 3VGOA 2K7AB 3VS6A 2KNOA 1O43A 5DC9A 2IZVA 2LCTA 1FU6A 2Y3AB 2PLDA 1A81A 3MXCA 1GHUA 1A07A 2PLEA 4EY0A 1O4IA 4OHIA 1AD5A 2LNWA 1YVLA 2CS0A 2EL8A 5EHRA 3NHNA 1MILA 2DVJA 1FBZA 1JU5A 2DCRA 2SHPA 1BMBA 2MQIA 1GRIA 2OZOA 3BUXB 1SKJA 1X0NA 1JYUA 4GL9E 4GWFA 1CJ1A 1O4CA 1WQUA 1I3ZA 3QWYA 1B47A 2DLYA 2SRCA 4OHHA 4OHEA 4QSYA 1AYCA 3PQZA 1LCKA 2L3TA 1O4FA 2H5KA 4F59A 2XP1A 1O4NA 3CD3A 4LUDA 3BUMB 3M7FA 1BFIA 1X6CA 5HKYA 3QWXX 3US4A 1O48A 2EU0A 5EHPA 1AYDA 1OO4A 1BKLA 2LNXA 1O45A 3HCKA 1HCTB 3TKZA 5GJIA 4JGHA 3VROA 1O4OA 3N8MA 3WA4A 3IMDA 2CR4A 3ZNIA 1SHDA 5CDWA 4JE4A 3OB1B 3KFJA 4ROJA 1SHAA 5EELA 2HDVA 1O4HA 2HDXA 1FHSA 2MC1A 1F2FA 2YSXA 1JYQA 1HCSB 3GXXA 2FO0A 4EIHA 1UUSA 3CWGA 4FBNA 1O4QA 3TL0A 2PNAA 2LQWA 1O46A 3BUNB 5DF6A 4FL3A 5DC0B 2IUIA 4WWQA 3VS4A 2BBUA 4F5AA 1A1AA 1O4PA 3S9KA 1FYRA 4K44A 2CIAA 1BKMA 1H9OA 2L4KA 1O42A 5D0JA 2DLZA 1R1PA 2JYQA 4FL2A 4NWGA 2HMHA 2KK6A 1SHBA 1AYAA 3MXYA 1O4GA 1O41A 4E68A 1SPRA 1O49A 3S8NA 1O4KA 1M61A 2RMXA 2AUGA 1AOTF 4H1OA 2ECDA 1CWDL 3VRQA 3OB2B 3PLFB 3OP0A 2CI8A 2MK2A 1OPLA 3VRPA 4D8KA 1O4DA 1D1ZA 1UURA 5IBMA 1BM2A 2ABLA 1AOUF 1PICA 3N7YA 4XZ1A 3VS5A 1AB2A 3VRZA 1LKLA 1BHHA 2C0IA 1A1EA 2PNBA 3GXWA 3PSJA 2HUWA 3VS3A 1JYRA 2QMSA 4XZ0A 3PJPA 1O4EA 4GPLB 3BKBA 5I6VA 4U17A 1R1SA 2OQ1A 3OVEA 1F1WA 4OHLA 3VRNA 4U1PA 4LUEA 1JWOA 3PFVA 4E93A 4NWFA 2CI9A 1TZEE 1CSZA 1QADA 1Z3KA 3VS2A 2IUHA 1P13A 1XA6A 2FCIA 3S8OA 3UYOA 1R1QA 1RQQC 1ZFPE 1OPKA 1AYBA 4TZIA 4P9VA 1CWEA 1NZVA 2L6KA 1IJRA 2VIFA 5J3XA 2GE9A 4M4ZA 3VS7A 1O4RA 4K11A 1KA6A 2B3OA 1MW4A 2EYZA 1FMKA 1BLKA 1O4MA 1O47A 1LKKA 1LUIA 2C0TA 2AOBA 1YVHA 1LCJA 1O4LA 2CBLA 2GSBA 3CXLA 1KC2A 1QG1E 4DGXA 1CSYA 5GJHA 2EYVA 1X27A 3IMJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H34 A;  4JEG A;  1LUN A;  2AOA A;  2HCK A;  2RSY A;  2RVF A;  3VRR A;  3VS0 A;  3IN8 A;  3GQI B;  3VRY A;  2EOB A;  1A1B A;  2EO3 A;  5HKZ A;  2EO6 A;  3C7I A;  1TCE A;  3BUO B;  1Y57 A;  5IBS A;  2MRK A;  4A4B A;  2DX0 A;  1RJA A;  1G83 A;  2PTK A;  3N84 A;  2C0O A;  2K79 B;  1LUK A;  2DM0 A;  2ROR A;  1BHF A;  1Y1U A;  1BG1 A;  4P9Z A;  1O4J A;  1NZL A;  5EG3 B;  1OO3 A;  3OV1 A;  1LUM A;  4A4C A;  4OHD A;  5AXI A;  2LQN A;  1KSW A;  4K45 A;  5EEQ A;  3UF4 A;  3VS1 A;  3T04 A;  1BFJ A;  2Y1N A;  4X6S A;  1A1C A;  1K9A A;  5AUL A;  2H8H A;  2MRJ A;  3S8L A;  5BO4 A;  1IS0 A;  1A08 A;  5DC4 A;  2IUG A;  1BF5 A;  1BHH B;  1O4A A;  3PS5 A;  1KA7 A;  3EAZ A;  3BUW B;  3HHM B;  1O4B A;  1D4W A;  1FU5 A;  3K2M A;  1FBV A;  3HIZ B;  3IN7 A;  3CBL A;  1O44 A;  2EYY A;  1NRV A;  3PSK A;  3MAZ A;  5KAZ A;  1A09 A;  2CRH A;  2EKX A;  1BLJ A;  2ETZ A;  2Y1M A;  1QCF A;  1D4T A;  3EAC A;  4DGP A;  4F5B A;  4K2R A;  5HKW A;  1SPS A;  1RPY A;  2C9W A;  1M27 A;  2YU7 A;  2H46 E;  4L1B B;  3VGO A;  2K7A B;  3VS6 A;  2KNO A;  1O43 A;  5DC9 A;  2IZV A;  2LCT A;  1FU6 A;  2Y3A B;  2PLD A;  1A81 A;  3MXC A;  1GHU A;  1A07 A;  2PLE A;  4EY0 A;  1O4I A;  4OHI A;  1AD5 A;  2LNW A;  1YVL A;  2CS0 A;  2EL8 A;  5EHR A;  3NHN A;  1MIL A;  2DVJ A;  1FBZ A;  1JU5 A;  2DCR A;  2SHP A;  1BMB A;  2MQI A;  1GRI A;  2OZO A;  3BUX B;  1SKJ A;  1X0N A;  1JYU A;  4GL9 E;  4GWF A;  1CJ1 A;  1O4C A;  1WQU A;  1I3Z A;  3QWY A;  1B47 A;  2DLY A;  2SRC A;  4OHH A;  4OHE A;  4QSY A;  1AYC A;  3PQZ A;  1LCK A;  2L3T A;  1O4F A;  2H5K A;  4F59 A;  2XP1 A;  1O4N A;  3CD3 A;  4LUD A;  3BUM B;  3M7F A;  1BFI A;  1X6C A;  5HKY A;  3QWX X;  3US4 A;  1O48 A;  2EU0 A;  5EHP A;  1AYD A;  1OO4 A;  1BKL A;  2LNX A;  1O45 A;  3HCK A;  1HCT B;  3TKZ A;  5GJI A;  4JGH A;  3VRO A;  1O4O A;  3N8M A;  3WA4 A;  3IMD A;  2CR4 A;  3ZNI A;  1SHD A;  5CDW A;  4JE4 A;  3OB1 B;  3KFJ A;  4ROJ A;  1SHA A;  5EEL A;  2HDV A;  1O4H A;  2HDX A;  1FHS A;  2MC1 A;  1F2F A;  2YSX A;  1JYQ A;  1HCS B;  3GXX A;  2FO0 A;  4EIH A;  1UUS A;  3CWG A;  4FBN A;  1O4Q A;  3TL0 A;  2PNA A;  2LQW A;  1O46 A;  3BUN B;  5DF6 A;  4FL3 A;  5DC0 B;  2IUI A;  4WWQ A;  3VS4 A;  2BBU A;  4F5A A;  1A1A A;  1O4P A;  3S9K A;  1FYR A;  4K44 A;  2CIA A;  1BKM A;  1H9O A;  2L4K A;  1O42 A;  5D0J A;  2DLZ A;  1R1P A;  2JYQ A;  4FL2 A;  4NWG A;  2HMH A;  2KK6 A;  1SHB A;  1AYA A;  3MXY A;  1O4G A;  1O41 A;  4E68 A;  1SPR A;  1O49 A;  3S8N A;  1O4K A;  1M61 A;  2RMX A;  2AUG A;  1AOT F;  4H1O A;  2ECD A;  1CWD L;  3VRQ A;  3OB2 B;  3PLF B;  3OP0 A;  2CI8 A;  2MK2 A;  1OPL A;  3VRP A;  4D8K A;  1O4D A;  1D1Z A;  1UUR A;  5IBM A;  1BM2 A;  2ABL A;  1AOU F;  1PIC A;  3N7Y A;  4XZ1 A;  3VS5 A;  1AB2 A;  3VRZ A;  1LKL A;  1BHH A;  2C0I A;  1A1E A;  2PNB A;  3GXW A;  3PSJ A;  2HUW A;  3VS3 A;  1JYR A;  2QMS A;  4XZ0 A;  3PJP A;  1O4E A;  4GPL B;  3BKB A;  5I6V A;  4U17 A;  1R1S A;  2OQ1 A;  3OVE A;  1F1W A;  4OHL A;  3VRN A;  4U1P A;  4LUE A;  1JWO A;  3PFV A;  4E93 A;  4NWF A;  2CI9 A;  1TZE E;  1CSZ A;  1QAD A;  1Z3K A;  3VS2 A;  2IUH A;  1P13 A;  1XA6 A;  2FCI A;  3S8O A;  3UYO A;  1R1Q A;  1RQQ C;  1ZFP E;  1OPK A;  1AYB A;  4TZI A;  4P9V A;  1CWE A;  1NZV A;  2L6K A;  1IJR A;  2VIF A;  5J3X A;  2GE9 A;  4M4Z A;  3VS7 A;  1O4R A;  4K11 A;  1KA6 A;  2B3O A;  1MW4 A;  2EYZ A;  1FMK A;  1BLK A;  1O4M A;  1O47 A;  1LKK A;  1LUI A;  2C0T A;  2AOB A;  1YVH A;  1LCJ A;  1O4L A;  2CBL A;  2GSB A;  3CXL A;  1KC2 A;  1QG1 E;  4DGX A;  1CSY A;  5GJH A;  2EYV A;  1X27 A;  3IMJ A; 
#chains in the Genus database with same CATH topology
 4H34 A;  4JEG A;  1LUN A;  2AOA A;  2HCK A;  2RSY A;  2RVF A;  3VRR A;  3VS0 A;  3IN8 A;  3GQI B;  3VRY A;  2EOB A;  1A1B A;  2EO3 A;  5HKZ A;  2EO6 A;  3C7I A;  1TCE A;  3BUO B;  1Y57 A;  5IBS A;  2MRK A;  4A4B A;  2DX0 A;  1RJA A;  1G83 A;  2PTK A;  3N84 A;  2C0O A;  2K79 B;  1LUK A;  2DM0 A;  2ROR A;  1BHF A;  1Y1U A;  1BG1 A;  4P9Z A;  1O4J A;  1NZL A;  5EG3 B;  1OO3 A;  3OV1 A;  1LUM A;  4A4C A;  4OHD A;  5AXI A;  2LQN A;  1KSW A;  4K45 A;  5EEQ A;  3UF4 A;  3VS1 A;  3T04 A;  1BFJ A;  2Y1N A;  4X6S A;  1A1C A;  1K9A A;  5AUL A;  2H8H A;  2MRJ A;  3S8L A;  5BO4 A;  1IS0 A;  1A08 A;  5DC4 A;  2IUG A;  1BF5 A;  1BHH B;  1O4A A;  3PS5 A;  1KA7 A;  3EAZ A;  3BUW B;  3HHM B;  1O4B A;  1D4W A;  1FU5 A;  3K2M A;  1FBV A;  3HIZ B;  3IN7 A;  3CBL A;  1O44 A;  2EYY A;  1NRV A;  3PSK A;  3MAZ A;  5KAZ A;  1A09 A;  2CRH A;  2EKX A;  1BLJ A;  2ETZ A;  2Y1M A;  1QCF A;  1D4T A;  3EAC A;  4DGP A;  4F5B A;  4K2R A;  5HKW A;  1SPS A;  1RPY A;  2C9W A;  1M27 A;  2YU7 A;  2H46 E;  4L1B B;  3VGO A;  2K7A B;  3VS6 A;  2KNO A;  1O43 A;  5DC9 A;  2IZV A;  2LCT A;  1FU6 A;  2Y3A B;  2PLD A;  1A81 A;  3MXC A;  1GHU A;  1A07 A;  2PLE A;  4EY0 A;  1O4I A;  4OHI A;  1AD5 A;  2LNW A;  1YVL A;  2CS0 A;  2EL8 A;  5EHR A;  3NHN A;  1MIL A;  3K2T A;  2DVJ A;  1FBZ A;  1JU5 A;  2DCR A;  2SHP A;  1BMB A;  2MQI A;  1GRI A;  2OZO A;  3BUX B;  1SKJ A;  1X0N A;  1JYU A;  4GL9 E;  4GWF A;  1CJ1 A;  1O4C A;  1WQU A;  1I3Z A;  3QWY A;  1B47 A;  2DLY A;  2SRC A;  4OHH A;  4OHE A;  4QSY A;  1AYC A;  3PQZ A;  1LCK A;  2L3T A;  1O4F A;  2H5K A;  4F59 A;  2XP1 A;  1O4N A;  3CD3 A;  4LUD A;  3BUM B;  3M7F A;  1BFI A;  1X6C A;  5HKY A;  3QWX X;  3US4 A;  1O48 A;  2EU0 A;  5EHP A;  1AYD A;  1OO4 A;  1BKL A;  2LNX A;  1O45 A;  3HCK A;  2LRA A;  3LYV A;  1HCT B;  3TKZ A;  5GJI A;  4JGH A;  3VRO A;  1O4O A;  3N8M A;  3WA4 A;  3IMD A;  2CR4 A;  3ZNI A;  1SHD A;  5CDW A;  4JE4 A;  3OB1 B;  3KFJ A;  4ROJ A;  1SHA A;  5EEL A;  2HDV A;  1O4H A;  2HDX A;  1FHS A;  2MC1 A;  1F2F A;  2YSX A;  1JYQ A;  1HCS B;  3GXX A;  2FO0 A;  4EIH A;  1UUS A;  2KGY A;  3CWG A;  4FBN A;  1O4Q A;  3TL0 A;  2PNA A;  2LQW A;  1O46 A;  3BUN B;  5DF6 A;  4FL3 A;  5DC0 B;  2IUI A;  4WWQ A;  3VS4 A;  2BBU A;  4F5A A;  1A1A A;  1O4P A;  3S9K A;  1FYR A;  4K44 A;  2CIA A;  1BKM A;  1H9O A;  2L4K A;  1O42 A;  5D0J A;  2DLZ A;  1R1P A;  2JYQ A;  4FL2 A;  4NWG A;  2HMH A;  2KK6 A;  1SHB A;  1AYA A;  3MXY A;  1O4G A;  1O41 A;  4E68 A;  1SPR A;  1O49 A;  3S8N A;  1O4K A;  1M61 A;  2RMX A;  2AUG A;  1AOT F;  4H1O A;  2ECD A;  1CWD L;  3VRQ A;  3OB2 B;  3PLF B;  3OP0 A;  2CI8 A;  2MK2 A;  1OPL A;  3VRP A;  4D8K A;  1O4D A;  1D1Z A;  1UUR A;  5IBM A;  1BM2 A;  2ABL A;  1AOU F;  1PIC A;  3N7Y A;  4XZ1 A;  3VS5 A;  1AB2 A;  3VRZ A;  1LKL A;  1BHH A;  2C0I A;  1A1E A;  2PNB A;  3GXW A;  3PSJ A;  2HUW A;  3VS3 A;  1JYR A;  2QMS A;  4XZ0 A;  3PJP A;  1O4E A;  4GPL B;  3BKB A;  5I6V A;  4U17 A;  1R1S A;  2OQ1 A;  3OVE A;  1F1W A;  4OHL A;  3VRN A;  4U1P A;  4LUE A;  1JWO A;  3PFV A;  4E93 A;  4NWF A;  2CI9 A;  1TZE E;  1CSZ A;  1QAD A;  1Z3K A;  3VS2 A;  2IUH A;  1P13 A;  1XA6 A;  2FCI A;  3S8O A;  3UYO A;  1R1Q A;  1RQQ C;  1ZFP E;  1OPK A;  1AYB A;  4TZI A;  4P9V A;  1CWE A;  1NZV A;  2L6K A;  1IJR A;  2VIF A;  5J3X A;  2GE9 A;  4M4Z A;  3VS7 A;  1O4R A;  4K11 A;  1KA6 A;  2B3O A;  1MW4 A;  2EYZ A;  1FMK A;  1BLK A;  1O4M A;  1O47 A;  1LKK A;  1LUI A;  2C0T A;  2AOB A;  1YVH A;  1LCJ A;  1O4L A;  2CBL A;  2GSB A;  3CXL A;  1KC2 A;  1QG1 E;  4DGX A;  1CSY A;  5GJH A;  2EYV A;  1X27 A;  3IMJ A; 
#chains in the Genus database with same CATH homology
 4H34 A;  4JEG A;  1LUN A;  2AOA A;  2HCK A;  2RSY A;  2RVF A;  3VRR A;  3VS0 A;  3IN8 A;  3GQI B;  3VRY A;  2EOB A;  1A1B A;  2EO3 A;  5HKZ A;  2EO6 A;  3C7I A;  1TCE A;  3BUO B;  1Y57 A;  5IBS A;  2MRK A;  4A4B A;  2DX0 A;  1RJA A;  1G83 A;  2PTK A;  3N84 A;  2C0O A;  2K79 B;  1LUK A;  2DM0 A;  2ROR A;  1BHF A;  1Y1U A;  1BG1 A;  4P9Z A;  1O4J A;  1NZL A;  5EG3 B;  1OO3 A;  3OV1 A;  1LUM A;  4A4C A;  4OHD A;  5AXI A;  2LQN A;  1KSW A;  4K45 A;  5EEQ A;  3UF4 A;  3VS1 A;  3T04 A;  1BFJ A;  2Y1N A;  4X6S A;  1A1C A;  1K9A A;  5AUL A;  2H8H A;  2MRJ A;  3S8L A;  5BO4 A;  1IS0 A;  1A08 A;  5DC4 A;  2IUG A;  1BF5 A;  1BHH B;  1O4A A;  3PS5 A;  1KA7 A;  3EAZ A;  3BUW B;  3HHM B;  1O4B A;  1D4W A;  1FU5 A;  3K2M A;  1FBV A;  3HIZ B;  3IN7 A;  3CBL A;  1O44 A;  2EYY A;  1NRV A;  3PSK A;  3MAZ A;  5KAZ A;  1A09 A;  2CRH A;  2EKX A;  1BLJ A;  2ETZ A;  2Y1M A;  1QCF A;  1D4T A;  3EAC A;  4DGP A;  4F5B A;  4K2R A;  5HKW A;  1SPS A;  1RPY A;  2C9W A;  1M27 A;  2YU7 A;  2H46 E;  4L1B B;  3VGO A;  2K7A B;  3VS6 A;  2KNO A;  1O43 A;  5DC9 A;  2IZV A;  2LCT A;  1FU6 A;  2Y3A B;  2PLD A;  1A81 A;  3MXC A;  1GHU A;  1A07 A;  2PLE A;  4EY0 A;  1O4I A;  4OHI A;  1AD5 A;  2LNW A;  1YVL A;  2CS0 A;  2EL8 A;  5EHR A;  3NHN A;  1MIL A;  2DVJ A;  1FBZ A;  1JU5 A;  2DCR A;  2SHP A;  1BMB A;  2MQI A;  1GRI A;  2OZO A;  3BUX B;  1SKJ A;  1X0N A;  1JYU A;  4GL9 E;  4GWF A;  1CJ1 A;  1O4C A;  1WQU A;  1I3Z A;  3QWY A;  1B47 A;  2DLY A;  2SRC A;  4OHH A;  4OHE A;  4QSY A;  1AYC A;  3PQZ A;  1LCK A;  2L3T A;  1O4F A;  2H5K A;  4F59 A;  2XP1 A;  1O4N A;  3CD3 A;  4LUD A;  3BUM B;  3M7F A;  1BFI A;  1X6C A;  5HKY A;  3QWX X;  3US4 A;  1O48 A;  2EU0 A;  5EHP A;  1AYD A;  1OO4 A;  1BKL A;  2LNX A;  1O45 A;  3HCK A;  1HCT B;  3TKZ A;  5GJI A;  4JGH A;  3VRO A;  1O4O A;  3N8M A;  3WA4 A;  3IMD A;  2CR4 A;  3ZNI A;  1SHD A;  5CDW A;  4JE4 A;  3OB1 B;  3KFJ A;  4ROJ A;  1SHA A;  5EEL A;  2HDV A;  1O4H A;  2HDX A;  1FHS A;  2MC1 A;  1F2F A;  2YSX A;  1JYQ A;  1HCS B;  3GXX A;  2FO0 A;  4EIH A;  1UUS A;  3CWG A;  4FBN A;  1O4Q A;  3TL0 A;  2PNA A;  2LQW A;  1O46 A;  3BUN B;  5DF6 A;  4FL3 A;  5DC0 B;  2IUI A;  4WWQ A;  3VS4 A;  2BBU A;  4F5A A;  1A1A A;  1O4P A;  3S9K A;  1FYR A;  4K44 A;  2CIA A;  1BKM A;  1H9O A;  2L4K A;  1O42 A;  5D0J A;  2DLZ A;  1R1P A;  2JYQ A;  4FL2 A;  4NWG A;  2HMH A;  2KK6 A;  1SHB A;  1AYA A;  3MXY A;  1O4G A;  1O41 A;  4E68 A;  1SPR A;  1O49 A;  3S8N A;  1O4K A;  1M61 A;  2RMX A;  2AUG A;  1AOT F;  4H1O A;  2ECD A;  1CWD L;  3VRQ A;  3OB2 B;  3PLF B;  3OP0 A;  2CI8 A;  2MK2 A;  1OPL A;  3VRP A;  4D8K A;  1O4D A;  1D1Z A;  1UUR A;  5IBM A;  1BM2 A;  2ABL A;  1AOU F;  1PIC A;  3N7Y A;  4XZ1 A;  3VS5 A;  1AB2 A;  3VRZ A;  1LKL A;  1BHH A;  2C0I A;  1A1E A;  2PNB A;  3GXW A;  3PSJ A;  2HUW A;  3VS3 A;  1JYR A;  2QMS A;  4XZ0 A;  3PJP A;  1O4E A;  4GPL B;  3BKB A;  5I6V A;  4U17 A;  1R1S A;  2OQ1 A;  3OVE A;  1F1W A;  4OHL A;  3VRN A;  4U1P A;  4LUE A;  1JWO A;  3PFV A;  4E93 A;  4NWF A;  2CI9 A;  1TZE E;  1CSZ A;  1QAD A;  1Z3K A;  3VS2 A;  2IUH A;  1P13 A;  1XA6 A;  2FCI A;  3S8O A;  3UYO A;  1R1Q A;  1RQQ C;  1ZFP E;  1OPK A;  1AYB A;  4TZI A;  4P9V A;  1CWE A;  1NZV A;  2L6K A;  1IJR A;  2VIF A;  5J3X A;  2GE9 A;  4M4Z A;  3VS7 A;  1O4R A;  4K11 A;  1KA6 A;  2B3O A;  1MW4 A;  2EYZ A;  1FMK A;  1BLK A;  1O4M A;  1O47 A;  1LKK A;  1LUI A;  2C0T A;  2AOB A;  1YVH A;  1LCJ A;  1O4L A;  2CBL A;  2GSB A;  3CXL A;  1KC2 A;  1QG1 E;  4DGX A;  1CSY A;  5GJH A;  2EYV A;  1X27 A;  3IMJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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