1O4CA

Crystal structure of sh2 in complex with phosphate.
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
105
structure length
104
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
molecule tags Signaling protein
source organism Homo sapiens
total genus 25
structure length 104
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4cA00
3PLFB 1LUNA 2DLYA 3TL0A 1Y57A 1NRVA 2LNWA 3VS5A 1BM2A 3VRYA 1O48A 4OHDA 1QG1E 3N84A 1JYRA 5I6VA 2C0OA 1SKJA 5EG3B 4XZ0A 4H34A 1F2FA 4E68A 1HCSB 3BUMB 2RMXA 2BBUA 1Z3KA 4ROJA 2DVJA 1BFJA 1MW4A 2H8HA 4LUEA 1CJ1A 4NWGA 1GHUA 4QSYA 2MRJA 2PNBA 4OHLA 1RJAA 1OPKA 2KNOA 1RQQC 3MXCA 3OV1A 4XZ1A 3VS4A 2SRCA 2QMSA 5AULA 2EO6A 1CWDL 1SHAA 1O4LA 1TZEE 4FBNA 1GRIA 3BUNB 3VRQA 3WA4A 2SHPA 3PQZA 4TZIA 5DF6A 1AOUF 5EHPA 5GJIA 3VRPA 2EOBA 2LQNA 5BO4A 4K2RA 1LCJA 2IUHA 3PFVA 1BFIA 2IZVA 1X0NA 2VIFA 1O41A 1M61A 1O45A 1FYRA 3PSKA 3NHNA 1O4JA 4JGHA 4GWFA 2PTKA 2Y3AB 1UUSA 3S9KA 3IN8A 3VGOA 1O4RA 2KK6A 1UURA 1O4OA 1HCTB 3VS6A 4L1BB 4K45A 2EYZA 1D1ZA 1WQUA 1LKKA 1OO4A 1AYCA 2HUWA 5EEQA 1BHFA 1FMKA 1KSWA 3PSJA 4LUDA 5EELA 2IUGA 2EKXA 3VROA 2RVFA 4DGPA 3S8OA 2K7AB 3CWGA 1F1WA 2RORA 1OPLA 5D0JA 4F59A 3MXYA 4NWFA 4EIHA 1FBVA 3VS1A 1QADA 2CIAA 2Y1NA 3OB1B 2DLZA 1M27A 3BUOB 1O44A 3PJPA 1O47A 1IS0A 2B3OA 1X6CA 4WWQA 2AOBA 2EU0A 1BF5A 3PS5A 2H5KA 1SHBA 3QWYA 2ETZA 3HIZB 1LKLA 2GE9A 2PLDA 1FU5A 1A1EA 1BMBA 1XA6A 1P13A 2OQ1A 1O4NA 1FHSA 1KA6A 2PLEA 3IN7A 1BLKA 4K11A 1A07A 3HCKA 1ZFPE 1AYBA 1X27A 1H9OA 4A4CA 1CWEA 1A08A 2AUGA 2FCIA 4DGXA 5HKZA 2LQWA 1OO3A 3VRZA 2CI9A 2FO0A 3GXXA 5DC9A 2MQIA 1BHHA 1A81A 3CXLA 2CS0A 2MC1A 5CDWA 3UF4A 4F5BA 2EYVA 1O4AA 1SHDA 1AD5A 1KC2A 2OZOA 2L3TA 3UYOA 1A1AA 2DCRA 1MILA 3C7IA 3US4A 3HHMB 2HDXA 2PNAA 3S8LA 1YVHA 3QWXX 1A1BA 1O4IA 5DC4A 1O4BA 1G83A 3CBLA 3EAZA 4OHHA 1CSYA 4U1PA 1BKLA 4OHEA 3M7FA 1BHHB 4X6SA 5IBMA 2YU7A 1SPSA 4EY0A 5HKYA 2YSXA 1KA7A 2EYYA 3MAZA 2ABLA 1D4TA 3N8MA 1JWOA 3VRNA 2CBLA 2EL8A 4FL2A 2IUIA 1O4PA 1AOTF 2L4KA 1O4GA 2DX0A 1O4KA 2L6KA 2MRKA 1TCEA 3VS2A 3OB2B 4K44A 1LCKA 1NZLA 1JU5A 3N7YA 1FBZA 1BKMA 2JYQA 1QCFA 4P9ZA 1R1PA 2Y1MA 3BUWB 3GQIB 1D4WA 2C0TA 1O4MA 1SPRA 3BUXB 2HCKA 3CD3A 3OP0A 1A1CA 1AB2A 1O4EA 4U17A 2C9WA 2ECDA 2RSYA 2HMHA 2EO3A 3K2MA 4E93A 4GPLB 1LUMA 3IMDA 1B47A 4JE4A 1YVLA 4P9VA 1NZVA 3S8NA 1CSZA 3VS7A 5DC0B 3GXWA 5KAZA 3VS0A 3EACA 3T04A 4A4BA 3ZNIA 5GJHA 2GSBA 1LUIA 2HDVA 2XP1A 2LCTA 4H1OA 1LUKA 2DM0A 2H46E 1JYUA 1O4FA 3IMJA 3TKZA 3BKBA 1R1QA 2CI8A 1IJRA 1O4CA 4M4ZA 1O46A 2AOAA 2CRHA 4FL3A 1O4HA 1JYQA 1A09A 1FU6A 5HKWA 4D8KA 2K79B 1O4QA 5AXIA 2CR4A 1I3ZA 1K9AA 1AYDA 5IBSA 2MK2A 1O42A 5EHRA 1AYAA 4F5AA 3VRRA 1O49A 3VS3A 1Y1UA 2C0IA 1PICA 1RPYA 1O4DA 4OHIA 5J3XA 3KFJA 3OVEA 1O43A 1R1SA 2LNXA 1BG1A 4GL9E 4JEGA 1BLJA
chains in the Genus database with same CATH superfamily
3PLFB 1LUNA 2DLYA 3TL0A 1Y57A 1NRVA 2LNWA 3VS5A 1BM2A 3VRYA 1O48A 4OHDA 1QG1E 3N84A 1JYRA 5I6VA 2C0OA 1SKJA 5EG3B 4XZ0A 4H34A 1F2FA 4E68A 1HCSB 3BUMB 2RMXA 2BBUA 1Z3KA 4ROJA 2DVJA 1BFJA 1MW4A 2H8HA 4LUEA 1CJ1A 4NWGA 1GHUA 4QSYA 2MRJA 2PNBA 4OHLA 1RJAA 1OPKA 2KNOA 1RQQC 3MXCA 3OV1A 4XZ1A 3VS4A 2SRCA 2QMSA 5AULA 2EO6A 1CWDL 2KGYA 1SHAA 1O4LA 1TZEE 4FBNA 1GRIA 3BUNB 3VRQA 3WA4A 2SHPA 3PQZA 4TZIA 5DF6A 3LYVA 1AOUF 5EHPA 5GJIA 3VRPA 2EOBA 2LQNA 5BO4A 4K2RA 1LCJA 2IUHA 3PFVA 1BFIA 2IZVA 1X0NA 2VIFA 1O41A 1M61A 1O45A 1FYRA 3PSKA 2LRAA 3NHNA 1O4JA 4JGHA 4GWFA 2PTKA 2Y3AB 1UUSA 3S9KA 3IN8A 3VGOA 1O4RA 2KK6A 1UURA 1O4OA 1HCTB 3VS6A 4L1BB 4K45A 2EYZA 1D1ZA 1WQUA 1LKKA 1OO4A 1AYCA 2HUWA 5EEQA 1BHFA 1FMKA 1KSWA 3PSJA 4LUDA 5EELA 2IUGA 2EKXA 3VROA 2RVFA 4DGPA 3S8OA 2K7AB 3CWGA 1F1WA 2RORA 1OPLA 5D0JA 4F59A 3MXYA 4NWFA 4EIHA 1FBVA 3VS1A 1QADA 2CIAA 2Y1NA 3OB1B 2DLZA 1M27A 3BUOB 1O44A 3PJPA 1O47A 1IS0A 2B3OA 1X6CA 4WWQA 2AOBA 2EU0A 1BF5A 3PS5A 2H5KA 1SHBA 3QWYA 2ETZA 3HIZB 1LKLA 2GE9A 2PLDA 1FU5A 1A1EA 1BMBA 1XA6A 1P13A 2OQ1A 1O4NA 1FHSA 1KA6A 2PLEA 3IN7A 1BLKA 4K11A 1A07A 3HCKA 1ZFPE 1AYBA 1X27A 1H9OA 4A4CA 1CWEA 1A08A 2AUGA 2FCIA 4DGXA 5HKZA 2LQWA 1OO3A 3VRZA 2CI9A 2FO0A 3GXXA 5DC9A 2MQIA 1BHHA 1A81A 3CXLA 2CS0A 2MC1A 5CDWA 3UF4A 4F5BA 2EYVA 1O4AA 1SHDA 1AD5A 1KC2A 2OZOA 2L3TA 3UYOA 1A1AA 2DCRA 1MILA 3C7IA 3US4A 3HHMB 2HDXA 2PNAA 3S8LA 1YVHA 3QWXX 1A1BA 1O4IA 5DC4A 1O4BA 1G83A 3CBLA 3EAZA 4OHHA 1CSYA 4U1PA 1BKLA 4OHEA 3M7FA 1BHHB 4X6SA 5IBMA 2YU7A 1SPSA 4EY0A 5HKYA 2YSXA 1KA7A 2EYYA 3MAZA 2ABLA 1D4TA 3N8MA 1JWOA 3VRNA 2CBLA 2EL8A 4FL2A 2IUIA 1O4PA 1AOTF 2L4KA 1O4GA 2DX0A 1O4KA 2L6KA 2MRKA 1TCEA 3VS2A 3OB2B 4K44A 1LCKA 1NZLA 1JU5A 3N7YA 1FBZA 1BKMA 2JYQA 1QCFA 4P9ZA 1R1PA 2Y1MA 3BUWB 3GQIB 1D4WA 2C0TA 1O4MA 1SPRA 3BUXB 2HCKA 3CD3A 3OP0A 1A1CA 1AB2A 1O4EA 4U17A 2C9WA 2ECDA 2RSYA 2HMHA 2EO3A 3K2MA 4E93A 4GPLB 1LUMA 3IMDA 1B47A 4JE4A 1YVLA 4P9VA 1NZVA 3S8NA 1CSZA 3VS7A 5DC0B 3GXWA 5KAZA 3VS0A 3EACA 3T04A 4A4BA 3ZNIA 5GJHA 2GSBA 1LUIA 2HDVA 2XP1A 3K2TA 2LCTA 4H1OA 1LUKA 2DM0A 2H46E 1JYUA 1O4FA 3IMJA 3TKZA 3BKBA 1R1QA 2CI8A 1IJRA 1O4CA 4M4ZA 1O46A 2AOAA 2CRHA 4FL3A 1O4HA 1JYQA 1A09A 1FU6A 5HKWA 4D8KA 2K79B 1O4QA 5AXIA 2CR4A 1I3ZA 1K9AA 1AYDA 5IBSA 2MK2A 1O42A 5EHRA 1AYAA 4F5AA 3VRRA 1O49A 3VS3A 1Y1UA 2C0IA 1PICA 1RPYA 1O4DA 4OHIA 5J3XA 3KFJA 3OVEA 1O43A 1R1SA 2LNXA 1BG1A 4GL9E 4JEGA 1BLJA
chains in the Genus database with same CATH topology
3PLFB 1LUNA 2DLYA 3TL0A 1Y57A 1NRVA 2LNWA 3VS5A 1BM2A 3VRYA 1O48A 4OHDA 1QG1E 3N84A 1JYRA 5I6VA 2C0OA 1SKJA 5EG3B 4XZ0A 4H34A 1F2FA 4E68A 1HCSB 3BUMB 2RMXA 2BBUA 1Z3KA 4ROJA 2DVJA 1BFJA 1MW4A 2H8HA 4LUEA 1CJ1A 4NWGA 1GHUA 4QSYA 2MRJA 2PNBA 4OHLA 1RJAA 1OPKA 2KNOA 1RQQC 3MXCA 3OV1A 4XZ1A 3VS4A 2SRCA 2QMSA 5AULA 2EO6A 1CWDL 1SHAA 1O4LA 1TZEE 4FBNA 1GRIA 3BUNB 3VRQA 3WA4A 2SHPA 3PQZA 4TZIA 5DF6A 1AOUF 5EHPA 5GJIA 3VRPA 2EOBA 2LQNA 5BO4A 4K2RA 1LCJA 2IUHA 3PFVA 1BFIA 2IZVA 1X0NA 2VIFA 1O41A 1M61A 1O45A 1FYRA 3PSKA 3NHNA 1O4JA 4JGHA 4GWFA 2PTKA 2Y3AB 1UUSA 3S9KA 3IN8A 3VGOA 1O4RA 2KK6A 1UURA 1O4OA 1HCTB 3VS6A 4L1BB 4K45A 2EYZA 1D1ZA 1WQUA 1LKKA 1OO4A 1AYCA 2HUWA 5EEQA 1BHFA 1FMKA 1KSWA 3PSJA 4LUDA 5EELA 2IUGA 2EKXA 3VROA 2RVFA 4DGPA 3S8OA 2K7AB 3CWGA 1F1WA 2RORA 1OPLA 5D0JA 4F59A 3MXYA 4NWFA 4EIHA 1FBVA 3VS1A 1QADA 2CIAA 2Y1NA 3OB1B 2DLZA 1M27A 3BUOB 1O44A 3PJPA 1O47A 1IS0A 2B3OA 1X6CA 4WWQA 2AOBA 2EU0A 1BF5A 3PS5A 2H5KA 1SHBA 3QWYA 2ETZA 3HIZB 1LKLA 2GE9A 2PLDA 1FU5A 1A1EA 1BMBA 1XA6A 1P13A 2OQ1A 1O4NA 1FHSA 1KA6A 2PLEA 3IN7A 1BLKA 4K11A 1A07A 3HCKA 1ZFPE 1AYBA 1X27A 1H9OA 4A4CA 1CWEA 1A08A 2AUGA 2FCIA 4DGXA 5HKZA 2LQWA 1OO3A 3VRZA 2CI9A 2FO0A 3GXXA 5DC9A 2MQIA 1BHHA 1A81A 3CXLA 2CS0A 2MC1A 5CDWA 3UF4A 4F5BA 2EYVA 1O4AA 1SHDA 1AD5A 1KC2A 2OZOA 2L3TA 3UYOA 1A1AA 2DCRA 1MILA 3C7IA 3US4A 3HHMB 2HDXA 2PNAA 3S8LA 1YVHA 3QWXX 1A1BA 1O4IA 5DC4A 1O4BA 1G83A 3CBLA 3EAZA 4OHHA 1CSYA 4U1PA 1BKLA 4OHEA 3M7FA 1BHHB 4X6SA 5IBMA 2YU7A 1SPSA 4EY0A 5HKYA 2YSXA 1KA7A 2EYYA 3MAZA 2ABLA 1D4TA 3N8MA 1JWOA 3VRNA 2CBLA 2EL8A 4FL2A 2IUIA 1O4PA 1AOTF 2L4KA 1O4GA 2DX0A 1O4KA 2L6KA 2MRKA 1TCEA 3VS2A 3OB2B 4K44A 1LCKA 1NZLA 1JU5A 3N7YA 1FBZA 1BKMA 2JYQA 1QCFA 4P9ZA 1R1PA 2Y1MA 3BUWB 3GQIB 1D4WA 2C0TA 1O4MA 1SPRA 3BUXB 2HCKA 3CD3A 3OP0A 1A1CA 1AB2A 1O4EA 4U17A 2C9WA 2ECDA 2RSYA 2HMHA 2EO3A 3K2MA 4E93A 4GPLB 1LUMA 3IMDA 1B47A 4JE4A 1YVLA 4P9VA 1NZVA 3S8NA 1CSZA 3VS7A 5DC0B 3GXWA 5KAZA 3VS0A 3EACA 3T04A 4A4BA 3ZNIA 5GJHA 2GSBA 1LUIA 2HDVA 2XP1A 2LCTA 4H1OA 1LUKA 2DM0A 2H46E 1JYUA 1O4FA 3IMJA 3TKZA 3BKBA 1R1QA 2CI8A 1IJRA 1O4CA 4M4ZA 1O46A 2AOAA 2CRHA 4FL3A 1O4HA 1JYQA 1A09A 1FU6A 5HKWA 4D8KA 2K79B 1O4QA 5AXIA 2CR4A 1I3ZA 1K9AA 1AYDA 5IBSA 2MK2A 1O42A 5EHRA 1AYAA 4F5AA 3VRRA 1O49A 3VS3A 1Y1UA 2C0IA 1PICA 1RPYA 1O4DA 4OHIA 5J3XA 3KFJA 3OVEA 1O43A 1R1SA 2LNXA 1BG1A 4GL9E 4JEGA 1BLJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PLF B;  1LUN A;  2DLY A;  3TL0 A;  1Y57 A;  1NRV A;  2LNW A;  3VS5 A;  1BM2 A;  3VRY A;  1O48 A;  4OHD A;  1QG1 E;  3N84 A;  1JYR A;  5I6V A;  2C0O A;  1SKJ A;  5EG3 B;  4XZ0 A;  4H34 A;  1F2F A;  4E68 A;  1HCS B;  3BUM B;  2RMX A;  2BBU A;  1Z3K A;  4ROJ A;  2DVJ A;  1BFJ A;  1MW4 A;  2H8H A;  4LUE A;  1CJ1 A;  4NWG A;  1GHU A;  4QSY A;  2MRJ A;  2PNB A;  4OHL A;  1RJA A;  1OPK A;  2KNO A;  1RQQ C;  3MXC A;  3OV1 A;  4XZ1 A;  3VS4 A;  2SRC A;  2QMS A;  5AUL A;  2EO6 A;  1CWD L;  1SHA A;  1O4L A;  1TZE E;  4FBN A;  1GRI A;  3BUN B;  3VRQ A;  3WA4 A;  2SHP A;  3PQZ A;  4TZI A;  5DF6 A;  1AOU F;  5EHP A;  5GJI A;  3VRP A;  2EOB A;  2LQN A;  5BO4 A;  4K2R A;  1LCJ A;  2IUH A;  3PFV A;  1BFI A;  2IZV A;  1X0N A;  2VIF A;  1O41 A;  1M61 A;  1O45 A;  1FYR A;  3PSK A;  3NHN A;  1O4J A;  4JGH A;  4GWF A;  2PTK A;  2Y3A B;  1UUS A;  3S9K A;  3IN8 A;  3VGO A;  1O4R A;  2KK6 A;  1UUR A;  1O4O A;  1HCT B;  3VS6 A;  4L1B B;  4K45 A;  2EYZ A;  1D1Z A;  1WQU A;  1LKK A;  1OO4 A;  1AYC A;  2HUW A;  5EEQ A;  1BHF A;  1FMK A;  1KSW A;  3PSJ A;  4LUD A;  5EEL A;  2IUG A;  2EKX A;  3VRO A;  2RVF A;  4DGP A;  3S8O A;  2K7A B;  3CWG A;  1F1W A;  2ROR A;  1OPL A;  5D0J A;  4F59 A;  3MXY A;  4NWF A;  4EIH A;  1FBV A;  3VS1 A;  1QAD A;  2CIA A;  2Y1N A;  3OB1 B;  2DLZ A;  1M27 A;  3BUO B;  1O44 A;  3PJP A;  1O47 A;  1IS0 A;  2B3O A;  1X6C A;  4WWQ A;  2AOB A;  2EU0 A;  1BF5 A;  3PS5 A;  2H5K A;  1SHB A;  3QWY A;  2ETZ A;  3HIZ B;  1LKL A;  2GE9 A;  2PLD A;  1FU5 A;  1A1E A;  1BMB A;  1XA6 A;  1P13 A;  2OQ1 A;  1O4N A;  1FHS A;  1KA6 A;  2PLE A;  3IN7 A;  1BLK A;  4K11 A;  1A07 A;  3HCK A;  1ZFP E;  1AYB A;  1X27 A;  1H9O A;  4A4C A;  1CWE A;  1A08 A;  2AUG A;  2FCI A;  4DGX A;  5HKZ A;  2LQW A;  1OO3 A;  3VRZ A;  2CI9 A;  2FO0 A;  3GXX A;  5DC9 A;  2MQI A;  1BHH A;  1A81 A;  3CXL A;  2CS0 A;  2MC1 A;  5CDW A;  3UF4 A;  4F5B A;  2EYV A;  1O4A A;  1SHD A;  1AD5 A;  1KC2 A;  2OZO A;  2L3T A;  3UYO A;  1A1A A;  2DCR A;  1MIL A;  3C7I A;  3US4 A;  3HHM B;  2HDX A;  2PNA A;  3S8L A;  1YVH A;  3QWX X;  1A1B A;  1O4I A;  5DC4 A;  1O4B A;  1G83 A;  3CBL A;  3EAZ A;  4OHH A;  1CSY A;  4U1P A;  1BKL A;  4OHE A;  3M7F A;  1BHH B;  4X6S A;  5IBM A;  2YU7 A;  1SPS A;  4EY0 A;  5HKY A;  2YSX A;  1KA7 A;  2EYY A;  3MAZ A;  2ABL A;  1D4T A;  3N8M A;  1JWO A;  3VRN A;  2CBL A;  2EL8 A;  4FL2 A;  2IUI A;  1O4P A;  1AOT F;  2L4K A;  1O4G A;  2DX0 A;  1O4K A;  2L6K A;  2MRK A;  1TCE A;  3VS2 A;  3OB2 B;  4K44 A;  1LCK A;  1NZL A;  1JU5 A;  3N7Y A;  1FBZ A;  1BKM A;  2JYQ A;  1QCF A;  4P9Z A;  1R1P A;  2Y1M A;  3BUW B;  3GQI B;  1D4W A;  2C0T A;  1O4M A;  1SPR A;  3BUX B;  2HCK A;  3CD3 A;  3OP0 A;  1A1C A;  1AB2 A;  1O4E A;  4U17 A;  2C9W A;  2ECD A;  2RSY A;  2HMH A;  2EO3 A;  3K2M A;  4E93 A;  4GPL B;  1LUM A;  3IMD A;  1B47 A;  4JE4 A;  1YVL A;  4P9V A;  1NZV A;  3S8N A;  1CSZ A;  3VS7 A;  5DC0 B;  3GXW A;  5KAZ A;  3VS0 A;  3EAC A;  3T04 A;  4A4B A;  3ZNI A;  5GJH A;  2GSB A;  1LUI A;  2HDV A;  2XP1 A;  2LCT A;  4H1O A;  1LUK A;  2DM0 A;  2H46 E;  1JYU A;  1O4F A;  3IMJ A;  3TKZ A;  3BKB A;  1R1Q A;  2CI8 A;  1IJR A;  1O4C A;  4M4Z A;  1O46 A;  2AOA A;  2CRH A;  4FL3 A;  1O4H A;  1JYQ A;  1A09 A;  1FU6 A;  5HKW A;  4D8K A;  2K79 B;  1O4Q A;  5AXI A;  2CR4 A;  1I3Z A;  1K9A A;  1AYD A;  5IBS A;  2MK2 A;  1O42 A;  5EHR A;  1AYA A;  4F5A A;  3VRR A;  1O49 A;  3VS3 A;  1Y1U A;  2C0I A;  1PIC A;  1RPY A;  1O4D A;  4OHI A;  5J3X A;  3KFJ A;  3OVE A;  1O43 A;  1R1S A;  2LNX A;  1BG1 A;  4GL9 E;  4JEG A;  1BLJ A; 
#chains in the Genus database with same CATH topology
 3PLF B;  1LUN A;  2DLY A;  3TL0 A;  1Y57 A;  1NRV A;  2LNW A;  3VS5 A;  1BM2 A;  3VRY A;  1O48 A;  4OHD A;  1QG1 E;  3N84 A;  1JYR A;  5I6V A;  2C0O A;  1SKJ A;  5EG3 B;  4XZ0 A;  4H34 A;  1F2F A;  4E68 A;  1HCS B;  3BUM B;  2RMX A;  2BBU A;  1Z3K A;  4ROJ A;  2DVJ A;  1BFJ A;  1MW4 A;  2H8H A;  4LUE A;  1CJ1 A;  4NWG A;  1GHU A;  4QSY A;  2MRJ A;  2PNB A;  4OHL A;  1RJA A;  1OPK A;  2KNO A;  1RQQ C;  3MXC A;  3OV1 A;  4XZ1 A;  3VS4 A;  2SRC A;  2QMS A;  5AUL A;  2EO6 A;  1CWD L;  2KGY A;  1SHA A;  1O4L A;  1TZE E;  4FBN A;  1GRI A;  3BUN B;  3VRQ A;  3WA4 A;  2SHP A;  3PQZ A;  4TZI A;  5DF6 A;  3LYV A;  1AOU F;  5EHP A;  5GJI A;  3VRP A;  2EOB A;  2LQN A;  5BO4 A;  4K2R A;  1LCJ A;  2IUH A;  3PFV A;  1BFI A;  2IZV A;  1X0N A;  2VIF A;  1O41 A;  1M61 A;  1O45 A;  1FYR A;  3PSK A;  2LRA A;  3NHN A;  1O4J A;  4JGH A;  4GWF A;  2PTK A;  2Y3A B;  1UUS A;  3S9K A;  3IN8 A;  3VGO A;  1O4R A;  2KK6 A;  1UUR A;  1O4O A;  1HCT B;  3VS6 A;  4L1B B;  4K45 A;  2EYZ A;  1D1Z A;  1WQU A;  1LKK A;  1OO4 A;  1AYC A;  2HUW A;  5EEQ A;  1BHF A;  1FMK A;  1KSW A;  3PSJ A;  4LUD A;  5EEL A;  2IUG A;  2EKX A;  3VRO A;  2RVF A;  4DGP A;  3S8O A;  2K7A B;  3CWG A;  1F1W A;  2ROR A;  1OPL A;  5D0J A;  4F59 A;  3MXY A;  4NWF A;  4EIH A;  1FBV A;  3VS1 A;  1QAD A;  2CIA A;  2Y1N A;  3OB1 B;  2DLZ A;  1M27 A;  3BUO B;  1O44 A;  3PJP A;  1O47 A;  1IS0 A;  2B3O A;  1X6C A;  4WWQ A;  2AOB A;  2EU0 A;  1BF5 A;  3PS5 A;  2H5K A;  1SHB A;  3QWY A;  2ETZ A;  3HIZ B;  1LKL A;  2GE9 A;  2PLD A;  1FU5 A;  1A1E A;  1BMB A;  1XA6 A;  1P13 A;  2OQ1 A;  1O4N A;  1FHS A;  1KA6 A;  2PLE A;  3IN7 A;  1BLK A;  4K11 A;  1A07 A;  3HCK A;  1ZFP E;  1AYB A;  1X27 A;  1H9O A;  4A4C A;  1CWE A;  1A08 A;  2AUG A;  2FCI A;  4DGX A;  5HKZ A;  2LQW A;  1OO3 A;  3VRZ A;  2CI9 A;  2FO0 A;  3GXX A;  5DC9 A;  2MQI A;  1BHH A;  1A81 A;  3CXL A;  2CS0 A;  2MC1 A;  5CDW A;  3UF4 A;  4F5B A;  2EYV A;  1O4A A;  1SHD A;  1AD5 A;  1KC2 A;  2OZO A;  2L3T A;  3UYO A;  1A1A A;  2DCR A;  1MIL A;  3C7I A;  3US4 A;  3HHM B;  2HDX A;  2PNA A;  3S8L A;  1YVH A;  3QWX X;  1A1B A;  1O4I A;  5DC4 A;  1O4B A;  1G83 A;  3CBL A;  3EAZ A;  4OHH A;  1CSY A;  4U1P A;  1BKL A;  4OHE A;  3M7F A;  1BHH B;  4X6S A;  5IBM A;  2YU7 A;  1SPS A;  4EY0 A;  5HKY A;  2YSX A;  1KA7 A;  2EYY A;  3MAZ A;  2ABL A;  1D4T A;  3N8M A;  1JWO A;  3VRN A;  2CBL A;  2EL8 A;  4FL2 A;  2IUI A;  1O4P A;  1AOT F;  2L4K A;  1O4G A;  2DX0 A;  1O4K A;  2L6K A;  2MRK A;  1TCE A;  3VS2 A;  3OB2 B;  4K44 A;  1LCK A;  1NZL A;  1JU5 A;  3N7Y A;  1FBZ A;  1BKM A;  2JYQ A;  1QCF A;  4P9Z A;  1R1P A;  2Y1M A;  3BUW B;  3GQI B;  1D4W A;  2C0T A;  1O4M A;  1SPR A;  3BUX B;  2HCK A;  3CD3 A;  3OP0 A;  1A1C A;  1AB2 A;  1O4E A;  4U17 A;  2C9W A;  2ECD A;  2RSY A;  2HMH A;  2EO3 A;  3K2M A;  4E93 A;  4GPL B;  1LUM A;  3IMD A;  1B47 A;  4JE4 A;  1YVL A;  4P9V A;  1NZV A;  3S8N A;  1CSZ A;  3VS7 A;  5DC0 B;  3GXW A;  5KAZ A;  3VS0 A;  3EAC A;  3T04 A;  4A4B A;  3ZNI A;  5GJH A;  2GSB A;  1LUI A;  2HDV A;  2XP1 A;  3K2T A;  2LCT A;  4H1O A;  1LUK A;  2DM0 A;  2H46 E;  1JYU A;  1O4F A;  3IMJ A;  3TKZ A;  3BKB A;  1R1Q A;  2CI8 A;  1IJR A;  1O4C A;  4M4Z A;  1O46 A;  2AOA A;  2CRH A;  4FL3 A;  1O4H A;  1JYQ A;  1A09 A;  1FU6 A;  5HKW A;  4D8K A;  2K79 B;  1O4Q A;  5AXI A;  2CR4 A;  1I3Z A;  1K9A A;  1AYD A;  5IBS A;  2MK2 A;  1O42 A;  5EHR A;  1AYA A;  4F5A A;  3VRR A;  1O49 A;  3VS3 A;  1Y1U A;  2C0I A;  1PIC A;  1RPY A;  1O4D A;  4OHI A;  5J3X A;  3KFJ A;  3OVE A;  1O43 A;  1R1S A;  2LNX A;  1BG1 A;  4GL9 E;  4JEG A;  1BLJ A; 
#chains in the Genus database with same CATH homology
 3PLF B;  1LUN A;  2DLY A;  3TL0 A;  1Y57 A;  1NRV A;  2LNW A;  3VS5 A;  1BM2 A;  3VRY A;  1O48 A;  4OHD A;  1QG1 E;  3N84 A;  1JYR A;  5I6V A;  2C0O A;  1SKJ A;  5EG3 B;  4XZ0 A;  4H34 A;  1F2F A;  4E68 A;  1HCS B;  3BUM B;  2RMX A;  2BBU A;  1Z3K A;  4ROJ A;  2DVJ A;  1BFJ A;  1MW4 A;  2H8H A;  4LUE A;  1CJ1 A;  4NWG A;  1GHU A;  4QSY A;  2MRJ A;  2PNB A;  4OHL A;  1RJA A;  1OPK A;  2KNO A;  1RQQ C;  3MXC A;  3OV1 A;  4XZ1 A;  3VS4 A;  2SRC A;  2QMS A;  5AUL A;  2EO6 A;  1CWD L;  1SHA A;  1O4L A;  1TZE E;  4FBN A;  1GRI A;  3BUN B;  3VRQ A;  3WA4 A;  2SHP A;  3PQZ A;  4TZI A;  5DF6 A;  1AOU F;  5EHP A;  5GJI A;  3VRP A;  2EOB A;  2LQN A;  5BO4 A;  4K2R A;  1LCJ A;  2IUH A;  3PFV A;  1BFI A;  2IZV A;  1X0N A;  2VIF A;  1O41 A;  1M61 A;  1O45 A;  1FYR A;  3PSK A;  3NHN A;  1O4J A;  4JGH A;  4GWF A;  2PTK A;  2Y3A B;  1UUS A;  3S9K A;  3IN8 A;  3VGO A;  1O4R A;  2KK6 A;  1UUR A;  1O4O A;  1HCT B;  3VS6 A;  4L1B B;  4K45 A;  2EYZ A;  1D1Z A;  1WQU A;  1LKK A;  1OO4 A;  1AYC A;  2HUW A;  5EEQ A;  1BHF A;  1FMK A;  1KSW A;  3PSJ A;  4LUD A;  5EEL A;  2IUG A;  2EKX A;  3VRO A;  2RVF A;  4DGP A;  3S8O A;  2K7A B;  3CWG A;  1F1W A;  2ROR A;  1OPL A;  5D0J A;  4F59 A;  3MXY A;  4NWF A;  4EIH A;  1FBV A;  3VS1 A;  1QAD A;  2CIA A;  2Y1N A;  3OB1 B;  2DLZ A;  1M27 A;  3BUO B;  1O44 A;  3PJP A;  1O47 A;  1IS0 A;  2B3O A;  1X6C A;  4WWQ A;  2AOB A;  2EU0 A;  1BF5 A;  3PS5 A;  2H5K A;  1SHB A;  3QWY A;  2ETZ A;  3HIZ B;  1LKL A;  2GE9 A;  2PLD A;  1FU5 A;  1A1E A;  1BMB A;  1XA6 A;  1P13 A;  2OQ1 A;  1O4N A;  1FHS A;  1KA6 A;  2PLE A;  3IN7 A;  1BLK A;  4K11 A;  1A07 A;  3HCK A;  1ZFP E;  1AYB A;  1X27 A;  1H9O A;  4A4C A;  1CWE A;  1A08 A;  2AUG A;  2FCI A;  4DGX A;  5HKZ A;  2LQW A;  1OO3 A;  3VRZ A;  2CI9 A;  2FO0 A;  3GXX A;  5DC9 A;  2MQI A;  1BHH A;  1A81 A;  3CXL A;  2CS0 A;  2MC1 A;  5CDW A;  3UF4 A;  4F5B A;  2EYV A;  1O4A A;  1SHD A;  1AD5 A;  1KC2 A;  2OZO A;  2L3T A;  3UYO A;  1A1A A;  2DCR A;  1MIL A;  3C7I A;  3US4 A;  3HHM B;  2HDX A;  2PNA A;  3S8L A;  1YVH A;  3QWX X;  1A1B A;  1O4I A;  5DC4 A;  1O4B A;  1G83 A;  3CBL A;  3EAZ A;  4OHH A;  1CSY A;  4U1P A;  1BKL A;  4OHE A;  3M7F A;  1BHH B;  4X6S A;  5IBM A;  2YU7 A;  1SPS A;  4EY0 A;  5HKY A;  2YSX A;  1KA7 A;  2EYY A;  3MAZ A;  2ABL A;  1D4T A;  3N8M A;  1JWO A;  3VRN A;  2CBL A;  2EL8 A;  4FL2 A;  2IUI A;  1O4P A;  1AOT F;  2L4K A;  1O4G A;  2DX0 A;  1O4K A;  2L6K A;  2MRK A;  1TCE A;  3VS2 A;  3OB2 B;  4K44 A;  1LCK A;  1NZL A;  1JU5 A;  3N7Y A;  1FBZ A;  1BKM A;  2JYQ A;  1QCF A;  4P9Z A;  1R1P A;  2Y1M A;  3BUW B;  3GQI B;  1D4W A;  2C0T A;  1O4M A;  1SPR A;  3BUX B;  2HCK A;  3CD3 A;  3OP0 A;  1A1C A;  1AB2 A;  1O4E A;  4U17 A;  2C9W A;  2ECD A;  2RSY A;  2HMH A;  2EO3 A;  3K2M A;  4E93 A;  4GPL B;  1LUM A;  3IMD A;  1B47 A;  4JE4 A;  1YVL A;  4P9V A;  1NZV A;  3S8N A;  1CSZ A;  3VS7 A;  5DC0 B;  3GXW A;  5KAZ A;  3VS0 A;  3EAC A;  3T04 A;  4A4B A;  3ZNI A;  5GJH A;  2GSB A;  1LUI A;  2HDV A;  2XP1 A;  2LCT A;  4H1O A;  1LUK A;  2DM0 A;  2H46 E;  1JYU A;  1O4F A;  3IMJ A;  3TKZ A;  3BKB A;  1R1Q A;  2CI8 A;  1IJR A;  1O4C A;  4M4Z A;  1O46 A;  2AOA A;  2CRH A;  4FL3 A;  1O4H A;  1JYQ A;  1A09 A;  1FU6 A;  5HKW A;  4D8K A;  2K79 B;  1O4Q A;  5AXI A;  2CR4 A;  1I3Z A;  1K9A A;  1AYD A;  5IBS A;  2MK2 A;  1O42 A;  5EHR A;  1AYA A;  4F5A A;  3VRR A;  1O49 A;  3VS3 A;  1Y1U A;  2C0I A;  1PIC A;  1RPY A;  1O4D A;  4OHI A;  5J3X A;  3KFJ A;  3OVE A;  1O43 A;  1R1S A;  2LNX A;  1BG1 A;  4GL9 E;  4JEG A;  1BLJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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