1O41A

Crystal structure of sh2 in complex with ru78300.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o41A00
2DM0A 3C7IA 2IUHA 5KAZA 3VRZA 3VS1A 3OV1A 3PS5A 1QG1E 3VRRA 2HCKA 2Y1NA 5IBMA 3GQIB 1BLKA 1A1EA 2MRKA 1KA7A 4JE4A 4GPLB 1BFIA 1A07A 1A1AA 2DX0A 1M27A 2CI8A 4OHLA 5HKYA 1O4NA 4U17A 1Y1UA 2OZOA 1CSZA 2CRHA 1OPKA 1SHAA 1O43A 2FCIA 3S9KA 2XP1A 3UYOA 1SPRA 3PLFB 1SPSA 1UURA 3M7FA 1R1QA 4LUDA 3N7YA 3OB2B 3CBLA 5HKZA 1WQUA 3K2MA 4OHHA 2EYZA 1CJ1A 1O4OA 3VRPA 2AOBA 4F5BA 1RQQC 1KSWA 5D0JA 1TCEA 5AXIA 1ZFPE 5CDWA 1LUKA 1BHHA 3US4A 1HCTB 2CBLA 5GJIA 4A4CA 3VROA 1Y57A 4TZIA 2PLEA 2C9WA 2AOAA 3IMJA 4L1BB 1CWEA 1O4PA 2HUWA 2LQWA 2CR4A 3BUOB 1BKMA 1BMBA 3PSJA 1O42A 1FYRA 4M4ZA 1LCKA 2H5KA 1BKLA 5IBSA 5DC4A 2PLDA 3VS4A 1SKJA 1JWOA 5J3XA 4XZ1A 4E93A 2LNXA 2EKXA 2CS0A 2H46E 2QMSA 4WWQA 1O47A 4A4BA 1IS0A 2EOBA 2ETZA 2HMHA 1AB2A 1IJRA 1O49A 4P9VA 4K2RA 1X0NA 3CWGA 4QSYA 3HIZB 1FMKA 1AOUF 4F5AA 2L4KA 3EAZA 4DGXA 4H1OA 2YSXA 4OHEA 3BUNB 3UF4A 5BO4A 1OPLA 3VGOA 2DVJA 1FU6A 3BUMB 1HCSB 2EU0A 2RORA 3GXXA 4D8KA 4OHDA 1O4RA 1H9OA 1D4TA 1O4IA 2Y1MA 3PQZA 3QWXX 2CI9A 3QWYA 3MXYA 1RJAA 3VS6A 2IZVA 1A1BA 1O4MA 1JYQA 5EEQA 3N8MA 3IN8A 2RMXA 1O4BA 1B47A 1LUMA 4GWFA 3CD3A 1RPYA 4P9ZA 1F1WA 1BF5A 3TKZA 4NWFA 3MXCA 1O4GA 2KK6A 3BUWB 1AYAA 2RSYA 2OQ1A 2Y3AB 1FBVA 5AULA 3S8OA 1AYCA 1OO3A 2IUGA 4U1PA 3WA4A 3VS5A 2MK2A 3ZNIA 3PSKA 1SHDA 2ECDA 1BFJA 4X6SA 2C0IA 1AYBA 1AD5A 2MC1A 1LUNA 4FL2A 1JYRA 1LUIA 3NHNA 1GRIA 3VS2A 4FBNA 2KNOA 1O4HA 2K79B 2IUIA 2EO3A 3OVEA 1G83A 1TZEE 2LQNA 4F59A 2YU7A 1QADA 3PJPA 4JGHA 2LNWA 2GE9A 1FU5A 2EO6A 1O4CA 4K45A 1CSYA 2LCTA 1M61A 2AUGA 2BBUA 3VS7A 1FBZA 2FO0A 1LKLA 5HKWA 4K44A 1BM2A 3VS3A 1O4QA 1O4JA 3VRYA 2K7AB 3VS0A 1LCJA 1O4AA 2PNBA 2EYYA 4E68A 4H34A 5EHPA 1JU5A 5EELA 1BHHB 2H8HA 1QCFA 2RVFA 4JEGA 4LUEA 2B3OA 3BKBA 3BUXB 4FL3A 3IN7A 1I3ZA 2DCRA 2SRCA 5DC9A 1R1PA 3IMDA 1BLJA 1K9AA 2HDXA 1NZVA 1X6CA 2SHPA 2HDVA 1D1ZA 3TL0A 2DLYA 2PNAA 1A09A 1O45A 2JYQA 3VRNA 1O4KA 1A81A 1OO4A 3N84A 1KC2A 3HHMB 1O4EA 1LKKA 2MQIA 2GSBA 2C0TA 2MRJA 3KFJA 1PICA 1MILA 1O4LA 5I6VA 1O4FA 3PFVA 1YVHA 1BG1A 4K11A 3CXLA 4OHIA 1P13A 3EACA 1Z3KA 2DLZA 3MAZA 4NWGA 3OP0A 2EL8A 4XZ0A 1O4DA 2L3TA 1R1SA 2CIAA 1A1CA 1CWDL 2C0OA 1XA6A 4DGPA 1AOTF 5DC0B 5EG3B 1BHFA 1YVLA 4EY0A 1O41A 1D4WA 1JYUA 3HCKA 4ROJA 3S8NA 1FHSA 2PTKA 1O46A 2VIFA 1X27A 1NZLA 1AYDA 1KA6A 1SHBA 1O44A 1GHUA 2EYVA 1NRVA 4EIHA 3GXWA 1A08A 3VRQA 1F2FA 2ABLA 5EHRA 5DF6A 3OB1B 4GL9E 3S8LA 2L6KA 5GJHA 1MW4A 1O48A 1UUSA 3T04A
chains in the Genus database with same CATH superfamily
2DM0A 3C7IA 2IUHA 3K2TA 5KAZA 2KGYA 3VRZA 3VS1A 3OV1A 3PS5A 1QG1E 3VRRA 2HCKA 2Y1NA 5IBMA 3GQIB 1BLKA 1A1EA 2MRKA 1KA7A 4JE4A 4GPLB 1BFIA 1A07A 1A1AA 2DX0A 1M27A 2CI8A 4OHLA 5HKYA 1O4NA 4U17A 1Y1UA 2OZOA 1CSZA 2CRHA 1OPKA 1SHAA 1O43A 2FCIA 3S9KA 2XP1A 3UYOA 1SPRA 3PLFB 1SPSA 1UURA 3M7FA 1R1QA 4LUDA 3N7YA 3OB2B 3CBLA 5HKZA 1WQUA 3K2MA 4OHHA 2EYZA 1CJ1A 1O4OA 3VRPA 2AOBA 4F5BA 1RQQC 1KSWA 3LYVA 5D0JA 1TCEA 5AXIA 1ZFPE 5CDWA 1LUKA 1BHHA 3US4A 1HCTB 2CBLA 5GJIA 4A4CA 3VROA 1Y57A 4TZIA 2PLEA 2C9WA 2AOAA 3IMJA 4L1BB 1CWEA 1O4PA 2HUWA 2LQWA 2CR4A 3BUOB 1BKMA 1BMBA 3PSJA 1O42A 1FYRA 4M4ZA 1LCKA 2H5KA 1BKLA 5IBSA 5DC4A 2PLDA 3VS4A 1SKJA 1JWOA 5J3XA 4XZ1A 4E93A 2LNXA 2EKXA 2CS0A 2H46E 2QMSA 4WWQA 1O47A 4A4BA 1IS0A 2EOBA 2ETZA 2HMHA 1AB2A 1IJRA 1O49A 4P9VA 4K2RA 1X0NA 3CWGA 4QSYA 3HIZB 1FMKA 1AOUF 4F5AA 2L4KA 3EAZA 4DGXA 4H1OA 2YSXA 4OHEA 3BUNB 3UF4A 5BO4A 1OPLA 3VGOA 2DVJA 1FU6A 3BUMB 1HCSB 2EU0A 2RORA 3GXXA 4D8KA 4OHDA 1O4RA 1H9OA 1D4TA 1O4IA 2Y1MA 3PQZA 3QWXX 2CI9A 3QWYA 3MXYA 1RJAA 3VS6A 2IZVA 1A1BA 1O4MA 1JYQA 5EEQA 3N8MA 3IN8A 2RMXA 1O4BA 1B47A 1LUMA 4GWFA 3CD3A 1RPYA 4P9ZA 1F1WA 1BF5A 3TKZA 4NWFA 3MXCA 1O4GA 2KK6A 3BUWB 1AYAA 2RSYA 2OQ1A 2Y3AB 1FBVA 5AULA 3S8OA 1AYCA 1OO3A 2IUGA 4U1PA 3WA4A 3VS5A 2MK2A 3ZNIA 3PSKA 1SHDA 2ECDA 1BFJA 4X6SA 2C0IA 1AYBA 1AD5A 2MC1A 1LUNA 4FL2A 1JYRA 1LUIA 3NHNA 1GRIA 3VS2A 4FBNA 2KNOA 1O4HA 2K79B 2IUIA 2EO3A 3OVEA 1G83A 1TZEE 2LQNA 4F59A 2YU7A 1QADA 3PJPA 4JGHA 2LNWA 2GE9A 1FU5A 2EO6A 1O4CA 4K45A 1CSYA 2LCTA 1M61A 2AUGA 2BBUA 3VS7A 1FBZA 2FO0A 1LKLA 5HKWA 4K44A 1BM2A 3VS3A 1O4QA 1O4JA 3VRYA 2K7AB 3VS0A 1LCJA 1O4AA 2PNBA 2EYYA 4E68A 4H34A 5EHPA 1JU5A 5EELA 1BHHB 2H8HA 1QCFA 2RVFA 4JEGA 4LUEA 2B3OA 3BKBA 3BUXB 4FL3A 3IN7A 1I3ZA 2DCRA 2SRCA 5DC9A 1R1PA 3IMDA 1BLJA 1K9AA 2HDXA 1NZVA 1X6CA 2SHPA 2HDVA 1D1ZA 3TL0A 2DLYA 2PNAA 1A09A 1O45A 2JYQA 3VRNA 1O4KA 1A81A 1OO4A 3N84A 1KC2A 3HHMB 1O4EA 1LKKA 2MQIA 2GSBA 2C0TA 2MRJA 3KFJA 1PICA 1MILA 1O4LA 5I6VA 1O4FA 3PFVA 1YVHA 1BG1A 4K11A 3CXLA 4OHIA 2LRAA 1P13A 3EACA 1Z3KA 2DLZA 3MAZA 4NWGA 3OP0A 2EL8A 4XZ0A 1O4DA 2L3TA 1R1SA 2CIAA 1A1CA 1CWDL 2C0OA 1XA6A 4DGPA 1AOTF 5DC0B 5EG3B 1BHFA 1YVLA 4EY0A 1O41A 1D4WA 1JYUA 3HCKA 4ROJA 3S8NA 1FHSA 2PTKA 1O46A 2VIFA 1X27A 1NZLA 1AYDA 1KA6A 1SHBA 1O44A 1GHUA 2EYVA 1NRVA 4EIHA 3GXWA 1A08A 3VRQA 1F2FA 2ABLA 5EHRA 5DF6A 3OB1B 4GL9E 3S8LA 2L6KA 5GJHA 1MW4A 1O48A 1UUSA 3T04A
chains in the Genus database with same CATH topology
2DM0A 3C7IA 2IUHA 5KAZA 3VRZA 3VS1A 3OV1A 3PS5A 1QG1E 3VRRA 2HCKA 2Y1NA 5IBMA 3GQIB 1BLKA 1A1EA 2MRKA 1KA7A 4JE4A 4GPLB 1BFIA 1A07A 1A1AA 2DX0A 1M27A 2CI8A 4OHLA 5HKYA 1O4NA 4U17A 1Y1UA 2OZOA 1CSZA 2CRHA 1OPKA 1SHAA 1O43A 2FCIA 3S9KA 2XP1A 3UYOA 1SPRA 3PLFB 1SPSA 1UURA 3M7FA 1R1QA 4LUDA 3N7YA 3OB2B 3CBLA 5HKZA 1WQUA 3K2MA 4OHHA 2EYZA 1CJ1A 1O4OA 3VRPA 2AOBA 4F5BA 1RQQC 1KSWA 5D0JA 1TCEA 5AXIA 1ZFPE 5CDWA 1LUKA 1BHHA 3US4A 1HCTB 2CBLA 5GJIA 4A4CA 3VROA 1Y57A 4TZIA 2PLEA 2C9WA 2AOAA 3IMJA 4L1BB 1CWEA 1O4PA 2HUWA 2LQWA 2CR4A 3BUOB 1BKMA 1BMBA 3PSJA 1O42A 1FYRA 4M4ZA 1LCKA 2H5KA 1BKLA 5IBSA 5DC4A 2PLDA 3VS4A 1SKJA 1JWOA 5J3XA 4XZ1A 4E93A 2LNXA 2EKXA 2CS0A 2H46E 2QMSA 4WWQA 1O47A 4A4BA 1IS0A 2EOBA 2ETZA 2HMHA 1AB2A 1IJRA 1O49A 4P9VA 4K2RA 1X0NA 3CWGA 4QSYA 3HIZB 1FMKA 1AOUF 4F5AA 2L4KA 3EAZA 4DGXA 4H1OA 2YSXA 4OHEA 3BUNB 3UF4A 5BO4A 1OPLA 3VGOA 2DVJA 1FU6A 3BUMB 1HCSB 2EU0A 2RORA 3GXXA 4D8KA 4OHDA 1O4RA 1H9OA 1D4TA 1O4IA 2Y1MA 3PQZA 3QWXX 2CI9A 3QWYA 3MXYA 1RJAA 3VS6A 2IZVA 1A1BA 1O4MA 1JYQA 5EEQA 3N8MA 3IN8A 2RMXA 1O4BA 1B47A 1LUMA 4GWFA 3CD3A 1RPYA 4P9ZA 1F1WA 1BF5A 3TKZA 4NWFA 3MXCA 1O4GA 2KK6A 3BUWB 1AYAA 2RSYA 2OQ1A 2Y3AB 1FBVA 5AULA 3S8OA 1AYCA 1OO3A 2IUGA 4U1PA 3WA4A 3VS5A 2MK2A 3ZNIA 3PSKA 1SHDA 2ECDA 1BFJA 4X6SA 2C0IA 1AYBA 1AD5A 2MC1A 1LUNA 4FL2A 1JYRA 1LUIA 3NHNA 1GRIA 3VS2A 4FBNA 2KNOA 1O4HA 2K79B 2IUIA 2EO3A 3OVEA 1G83A 1TZEE 2LQNA 4F59A 2YU7A 1QADA 3PJPA 4JGHA 2LNWA 2GE9A 1FU5A 2EO6A 1O4CA 4K45A 1CSYA 2LCTA 1M61A 2AUGA 2BBUA 3VS7A 1FBZA 2FO0A 1LKLA 5HKWA 4K44A 1BM2A 3VS3A 1O4QA 1O4JA 3VRYA 2K7AB 3VS0A 1LCJA 1O4AA 2PNBA 2EYYA 4E68A 4H34A 5EHPA 1JU5A 5EELA 1BHHB 2H8HA 1QCFA 2RVFA 4JEGA 4LUEA 2B3OA 3BKBA 3BUXB 4FL3A 3IN7A 1I3ZA 2DCRA 2SRCA 5DC9A 1R1PA 3IMDA 1BLJA 1K9AA 2HDXA 1NZVA 1X6CA 2SHPA 2HDVA 1D1ZA 3TL0A 2DLYA 2PNAA 1A09A 1O45A 2JYQA 3VRNA 1O4KA 1A81A 1OO4A 3N84A 1KC2A 3HHMB 1O4EA 1LKKA 2MQIA 2GSBA 2C0TA 2MRJA 3KFJA 1PICA 1MILA 1O4LA 5I6VA 1O4FA 3PFVA 1YVHA 1BG1A 4K11A 3CXLA 4OHIA 1P13A 3EACA 1Z3KA 2DLZA 3MAZA 4NWGA 3OP0A 2EL8A 4XZ0A 1O4DA 2L3TA 1R1SA 2CIAA 1A1CA 1CWDL 2C0OA 1XA6A 4DGPA 1AOTF 5DC0B 5EG3B 1BHFA 1YVLA 4EY0A 1O41A 1D4WA 1JYUA 3HCKA 4ROJA 3S8NA 1FHSA 2PTKA 1O46A 2VIFA 1X27A 1NZLA 1AYDA 1KA6A 1SHBA 1O44A 1GHUA 2EYVA 1NRVA 4EIHA 3GXWA 1A08A 3VRQA 1F2FA 2ABLA 5EHRA 5DF6A 3OB1B 4GL9E 3S8LA 2L6KA 5GJHA 1MW4A 1O48A 1UUSA 3T04A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DM0 A;  3C7I A;  2IUH A;  5KAZ A;  3VRZ A;  3VS1 A;  3OV1 A;  3PS5 A;  1QG1 E;  3VRR A;  2HCK A;  2Y1N A;  5IBM A;  3GQI B;  1BLK A;  1A1E A;  2MRK A;  1KA7 A;  4JE4 A;  4GPL B;  1BFI A;  1A07 A;  1A1A A;  2DX0 A;  1M27 A;  2CI8 A;  4OHL A;  5HKY A;  1O4N A;  4U17 A;  1Y1U A;  2OZO A;  1CSZ A;  2CRH A;  1OPK A;  1SHA A;  1O43 A;  2FCI A;  3S9K A;  2XP1 A;  3UYO A;  1SPR A;  3PLF B;  1SPS A;  1UUR A;  3M7F A;  1R1Q A;  4LUD A;  3N7Y A;  3OB2 B;  3CBL A;  5HKZ A;  1WQU A;  3K2M A;  4OHH A;  2EYZ A;  1CJ1 A;  1O4O A;  3VRP A;  2AOB A;  4F5B A;  1RQQ C;  1KSW A;  5D0J A;  1TCE A;  5AXI A;  1ZFP E;  5CDW A;  1LUK A;  1BHH A;  3US4 A;  1HCT B;  2CBL A;  5GJI A;  4A4C A;  3VRO A;  1Y57 A;  4TZI A;  2PLE A;  2C9W A;  2AOA A;  3IMJ A;  4L1B B;  1CWE A;  1O4P A;  2HUW A;  2LQW A;  2CR4 A;  3BUO B;  1BKM A;  1BMB A;  3PSJ A;  1O42 A;  1FYR A;  4M4Z A;  1LCK A;  2H5K A;  1BKL A;  5IBS A;  5DC4 A;  2PLD A;  3VS4 A;  1SKJ A;  1JWO A;  5J3X A;  4XZ1 A;  4E93 A;  2LNX A;  2EKX A;  2CS0 A;  2H46 E;  2QMS A;  4WWQ A;  1O47 A;  4A4B A;  1IS0 A;  2EOB A;  2ETZ A;  2HMH A;  1AB2 A;  1IJR A;  1O49 A;  4P9V A;  4K2R A;  1X0N A;  3CWG A;  4QSY A;  3HIZ B;  1FMK A;  1AOU F;  4F5A A;  2L4K A;  3EAZ A;  4DGX A;  4H1O A;  2YSX A;  4OHE A;  3BUN B;  3UF4 A;  5BO4 A;  1OPL A;  3VGO A;  2DVJ A;  1FU6 A;  3BUM B;  1HCS B;  2EU0 A;  2ROR A;  3GXX A;  4D8K A;  4OHD A;  1O4R A;  1H9O A;  1D4T A;  1O4I A;  2Y1M A;  3PQZ A;  3QWX X;  2CI9 A;  3QWY A;  3MXY A;  1RJA A;  3VS6 A;  2IZV A;  1A1B A;  1O4M A;  1JYQ A;  5EEQ A;  3N8M A;  3IN8 A;  2RMX A;  1O4B A;  1B47 A;  1LUM A;  4GWF A;  3CD3 A;  1RPY A;  4P9Z A;  1F1W A;  1BF5 A;  3TKZ A;  4NWF A;  3MXC A;  1O4G A;  2KK6 A;  3BUW B;  1AYA A;  2RSY A;  2OQ1 A;  2Y3A B;  1FBV A;  5AUL A;  3S8O A;  1AYC A;  1OO3 A;  2IUG A;  4U1P A;  3WA4 A;  3VS5 A;  2MK2 A;  3ZNI A;  3PSK A;  1SHD A;  2ECD A;  1BFJ A;  4X6S A;  2C0I A;  1AYB A;  1AD5 A;  2MC1 A;  1LUN A;  4FL2 A;  1JYR A;  1LUI A;  3NHN A;  1GRI A;  3VS2 A;  4FBN A;  2KNO A;  1O4H A;  2K79 B;  2IUI A;  2EO3 A;  3OVE A;  1G83 A;  1TZE E;  2LQN A;  4F59 A;  2YU7 A;  1QAD A;  3PJP A;  4JGH A;  2LNW A;  2GE9 A;  1FU5 A;  2EO6 A;  1O4C A;  4K45 A;  1CSY A;  2LCT A;  1M61 A;  2AUG A;  2BBU A;  3VS7 A;  1FBZ A;  2FO0 A;  1LKL A;  5HKW A;  4K44 A;  1BM2 A;  3VS3 A;  1O4Q A;  1O4J A;  3VRY A;  2K7A B;  3VS0 A;  1LCJ A;  1O4A A;  2PNB A;  2EYY A;  4E68 A;  4H34 A;  5EHP A;  1JU5 A;  5EEL A;  1BHH B;  2H8H A;  1QCF A;  2RVF A;  4JEG A;  4LUE A;  2B3O A;  3BKB A;  3BUX B;  4FL3 A;  3IN7 A;  1I3Z A;  2DCR A;  2SRC A;  5DC9 A;  1R1P A;  3IMD A;  1BLJ A;  1K9A A;  2HDX A;  1NZV A;  1X6C A;  2SHP A;  2HDV A;  1D1Z A;  3TL0 A;  2DLY A;  2PNA A;  1A09 A;  1O45 A;  2JYQ A;  3VRN A;  1O4K A;  1A81 A;  1OO4 A;  3N84 A;  1KC2 A;  3HHM B;  1O4E A;  1LKK A;  2MQI A;  2GSB A;  2C0T A;  2MRJ A;  3KFJ A;  1PIC A;  1MIL A;  1O4L A;  5I6V A;  1O4F A;  3PFV A;  1YVH A;  1BG1 A;  4K11 A;  3CXL A;  4OHI A;  1P13 A;  3EAC A;  1Z3K A;  2DLZ A;  3MAZ A;  4NWG A;  3OP0 A;  2EL8 A;  4XZ0 A;  1O4D A;  2L3T A;  1R1S A;  2CIA A;  1A1C A;  1CWD L;  2C0O A;  1XA6 A;  4DGP A;  1AOT F;  5DC0 B;  5EG3 B;  1BHF A;  1YVL A;  4EY0 A;  1O41 A;  1D4W A;  1JYU A;  3HCK A;  4ROJ A;  3S8N A;  1FHS A;  2PTK A;  1O46 A;  2VIF A;  1X27 A;  1NZL A;  1AYD A;  1KA6 A;  1SHB A;  1O44 A;  1GHU A;  2EYV A;  1NRV A;  4EIH A;  3GXW A;  1A08 A;  3VRQ A;  1F2F A;  2ABL A;  5EHR A;  5DF6 A;  3OB1 B;  4GL9 E;  3S8L A;  2L6K A;  5GJH A;  1MW4 A;  1O48 A;  1UUS A;  3T04 A; 
#chains in the Genus database with same CATH topology
 2DM0 A;  3C7I A;  2IUH A;  3K2T A;  5KAZ A;  2KGY A;  3VRZ A;  3VS1 A;  3OV1 A;  3PS5 A;  1QG1 E;  3VRR A;  2HCK A;  2Y1N A;  5IBM A;  3GQI B;  1BLK A;  1A1E A;  2MRK A;  1KA7 A;  4JE4 A;  4GPL B;  1BFI A;  1A07 A;  1A1A A;  2DX0 A;  1M27 A;  2CI8 A;  4OHL A;  5HKY A;  1O4N A;  4U17 A;  1Y1U A;  2OZO A;  1CSZ A;  2CRH A;  1OPK A;  1SHA A;  1O43 A;  2FCI A;  3S9K A;  2XP1 A;  3UYO A;  1SPR A;  3PLF B;  1SPS A;  1UUR A;  3M7F A;  1R1Q A;  4LUD A;  3N7Y A;  3OB2 B;  3CBL A;  5HKZ A;  1WQU A;  3K2M A;  4OHH A;  2EYZ A;  1CJ1 A;  1O4O A;  3VRP A;  2AOB A;  4F5B A;  1RQQ C;  1KSW A;  3LYV A;  5D0J A;  1TCE A;  5AXI A;  1ZFP E;  5CDW A;  1LUK A;  1BHH A;  3US4 A;  1HCT B;  2CBL A;  5GJI A;  4A4C A;  3VRO A;  1Y57 A;  4TZI A;  2PLE A;  2C9W A;  2AOA A;  3IMJ A;  4L1B B;  1CWE A;  1O4P A;  2HUW A;  2LQW A;  2CR4 A;  3BUO B;  1BKM A;  1BMB A;  3PSJ A;  1O42 A;  1FYR A;  4M4Z A;  1LCK A;  2H5K A;  1BKL A;  5IBS A;  5DC4 A;  2PLD A;  3VS4 A;  1SKJ A;  1JWO A;  5J3X A;  4XZ1 A;  4E93 A;  2LNX A;  2EKX A;  2CS0 A;  2H46 E;  2QMS A;  4WWQ A;  1O47 A;  4A4B A;  1IS0 A;  2EOB A;  2ETZ A;  2HMH A;  1AB2 A;  1IJR A;  1O49 A;  4P9V A;  4K2R A;  1X0N A;  3CWG A;  4QSY A;  3HIZ B;  1FMK A;  1AOU F;  4F5A A;  2L4K A;  3EAZ A;  4DGX A;  4H1O A;  2YSX A;  4OHE A;  3BUN B;  3UF4 A;  5BO4 A;  1OPL A;  3VGO A;  2DVJ A;  1FU6 A;  3BUM B;  1HCS B;  2EU0 A;  2ROR A;  3GXX A;  4D8K A;  4OHD A;  1O4R A;  1H9O A;  1D4T A;  1O4I A;  2Y1M A;  3PQZ A;  3QWX X;  2CI9 A;  3QWY A;  3MXY A;  1RJA A;  3VS6 A;  2IZV A;  1A1B A;  1O4M A;  1JYQ A;  5EEQ A;  3N8M A;  3IN8 A;  2RMX A;  1O4B A;  1B47 A;  1LUM A;  4GWF A;  3CD3 A;  1RPY A;  4P9Z A;  1F1W A;  1BF5 A;  3TKZ A;  4NWF A;  3MXC A;  1O4G A;  2KK6 A;  3BUW B;  1AYA A;  2RSY A;  2OQ1 A;  2Y3A B;  1FBV A;  5AUL A;  3S8O A;  1AYC A;  1OO3 A;  2IUG A;  4U1P A;  3WA4 A;  3VS5 A;  2MK2 A;  3ZNI A;  3PSK A;  1SHD A;  2ECD A;  1BFJ A;  4X6S A;  2C0I A;  1AYB A;  1AD5 A;  2MC1 A;  1LUN A;  4FL2 A;  1JYR A;  1LUI A;  3NHN A;  1GRI A;  3VS2 A;  4FBN A;  2KNO A;  1O4H A;  2K79 B;  2IUI A;  2EO3 A;  3OVE A;  1G83 A;  1TZE E;  2LQN A;  4F59 A;  2YU7 A;  1QAD A;  3PJP A;  4JGH A;  2LNW A;  2GE9 A;  1FU5 A;  2EO6 A;  1O4C A;  4K45 A;  1CSY A;  2LCT A;  1M61 A;  2AUG A;  2BBU A;  3VS7 A;  1FBZ A;  2FO0 A;  1LKL A;  5HKW A;  4K44 A;  1BM2 A;  3VS3 A;  1O4Q A;  1O4J A;  3VRY A;  2K7A B;  3VS0 A;  1LCJ A;  1O4A A;  2PNB A;  2EYY A;  4E68 A;  4H34 A;  5EHP A;  1JU5 A;  5EEL A;  1BHH B;  2H8H A;  1QCF A;  2RVF A;  4JEG A;  4LUE A;  2B3O A;  3BKB A;  3BUX B;  4FL3 A;  3IN7 A;  1I3Z A;  2DCR A;  2SRC A;  5DC9 A;  1R1P A;  3IMD A;  1BLJ A;  1K9A A;  2HDX A;  1NZV A;  1X6C A;  2SHP A;  2HDV A;  1D1Z A;  3TL0 A;  2DLY A;  2PNA A;  1A09 A;  1O45 A;  2JYQ A;  3VRN A;  1O4K A;  1A81 A;  1OO4 A;  3N84 A;  1KC2 A;  3HHM B;  1O4E A;  1LKK A;  2MQI A;  2GSB A;  2C0T A;  2MRJ A;  3KFJ A;  1PIC A;  1MIL A;  1O4L A;  5I6V A;  1O4F A;  3PFV A;  1YVH A;  1BG1 A;  4K11 A;  3CXL A;  4OHI A;  2LRA A;  1P13 A;  3EAC A;  1Z3K A;  2DLZ A;  3MAZ A;  4NWG A;  3OP0 A;  2EL8 A;  4XZ0 A;  1O4D A;  2L3T A;  1R1S A;  2CIA A;  1A1C A;  1CWD L;  2C0O A;  1XA6 A;  4DGP A;  1AOT F;  5DC0 B;  5EG3 B;  1BHF A;  1YVL A;  4EY0 A;  1O41 A;  1D4W A;  1JYU A;  3HCK A;  4ROJ A;  3S8N A;  1FHS A;  2PTK A;  1O46 A;  2VIF A;  1X27 A;  1NZL A;  1AYD A;  1KA6 A;  1SHB A;  1O44 A;  1GHU A;  2EYV A;  1NRV A;  4EIH A;  3GXW A;  1A08 A;  3VRQ A;  1F2F A;  2ABL A;  5EHR A;  5DF6 A;  3OB1 B;  4GL9 E;  3S8L A;  2L6K A;  5GJH A;  1MW4 A;  1O48 A;  1UUS A;  3T04 A; 
#chains in the Genus database with same CATH homology
 2DM0 A;  3C7I A;  2IUH A;  5KAZ A;  3VRZ A;  3VS1 A;  3OV1 A;  3PS5 A;  1QG1 E;  3VRR A;  2HCK A;  2Y1N A;  5IBM A;  3GQI B;  1BLK A;  1A1E A;  2MRK A;  1KA7 A;  4JE4 A;  4GPL B;  1BFI A;  1A07 A;  1A1A A;  2DX0 A;  1M27 A;  2CI8 A;  4OHL A;  5HKY A;  1O4N A;  4U17 A;  1Y1U A;  2OZO A;  1CSZ A;  2CRH A;  1OPK A;  1SHA A;  1O43 A;  2FCI A;  3S9K A;  2XP1 A;  3UYO A;  1SPR A;  3PLF B;  1SPS A;  1UUR A;  3M7F A;  1R1Q A;  4LUD A;  3N7Y A;  3OB2 B;  3CBL A;  5HKZ A;  1WQU A;  3K2M A;  4OHH A;  2EYZ A;  1CJ1 A;  1O4O A;  3VRP A;  2AOB A;  4F5B A;  1RQQ C;  1KSW A;  5D0J A;  1TCE A;  5AXI A;  1ZFP E;  5CDW A;  1LUK A;  1BHH A;  3US4 A;  1HCT B;  2CBL A;  5GJI A;  4A4C A;  3VRO A;  1Y57 A;  4TZI A;  2PLE A;  2C9W A;  2AOA A;  3IMJ A;  4L1B B;  1CWE A;  1O4P A;  2HUW A;  2LQW A;  2CR4 A;  3BUO B;  1BKM A;  1BMB A;  3PSJ A;  1O42 A;  1FYR A;  4M4Z A;  1LCK A;  2H5K A;  1BKL A;  5IBS A;  5DC4 A;  2PLD A;  3VS4 A;  1SKJ A;  1JWO A;  5J3X A;  4XZ1 A;  4E93 A;  2LNX A;  2EKX A;  2CS0 A;  2H46 E;  2QMS A;  4WWQ A;  1O47 A;  4A4B A;  1IS0 A;  2EOB A;  2ETZ A;  2HMH A;  1AB2 A;  1IJR A;  1O49 A;  4P9V A;  4K2R A;  1X0N A;  3CWG A;  4QSY A;  3HIZ B;  1FMK A;  1AOU F;  4F5A A;  2L4K A;  3EAZ A;  4DGX A;  4H1O A;  2YSX A;  4OHE A;  3BUN B;  3UF4 A;  5BO4 A;  1OPL A;  3VGO A;  2DVJ A;  1FU6 A;  3BUM B;  1HCS B;  2EU0 A;  2ROR A;  3GXX A;  4D8K A;  4OHD A;  1O4R A;  1H9O A;  1D4T A;  1O4I A;  2Y1M A;  3PQZ A;  3QWX X;  2CI9 A;  3QWY A;  3MXY A;  1RJA A;  3VS6 A;  2IZV A;  1A1B A;  1O4M A;  1JYQ A;  5EEQ A;  3N8M A;  3IN8 A;  2RMX A;  1O4B A;  1B47 A;  1LUM A;  4GWF A;  3CD3 A;  1RPY A;  4P9Z A;  1F1W A;  1BF5 A;  3TKZ A;  4NWF A;  3MXC A;  1O4G A;  2KK6 A;  3BUW B;  1AYA A;  2RSY A;  2OQ1 A;  2Y3A B;  1FBV A;  5AUL A;  3S8O A;  1AYC A;  1OO3 A;  2IUG A;  4U1P A;  3WA4 A;  3VS5 A;  2MK2 A;  3ZNI A;  3PSK A;  1SHD A;  2ECD A;  1BFJ A;  4X6S A;  2C0I A;  1AYB A;  1AD5 A;  2MC1 A;  1LUN A;  4FL2 A;  1JYR A;  1LUI A;  3NHN A;  1GRI A;  3VS2 A;  4FBN A;  2KNO A;  1O4H A;  2K79 B;  2IUI A;  2EO3 A;  3OVE A;  1G83 A;  1TZE E;  2LQN A;  4F59 A;  2YU7 A;  1QAD A;  3PJP A;  4JGH A;  2LNW A;  2GE9 A;  1FU5 A;  2EO6 A;  1O4C A;  4K45 A;  1CSY A;  2LCT A;  1M61 A;  2AUG A;  2BBU A;  3VS7 A;  1FBZ A;  2FO0 A;  1LKL A;  5HKW A;  4K44 A;  1BM2 A;  3VS3 A;  1O4Q A;  1O4J A;  3VRY A;  2K7A B;  3VS0 A;  1LCJ A;  1O4A A;  2PNB A;  2EYY A;  4E68 A;  4H34 A;  5EHP A;  1JU5 A;  5EEL A;  1BHH B;  2H8H A;  1QCF A;  2RVF A;  4JEG A;  4LUE A;  2B3O A;  3BKB A;  3BUX B;  4FL3 A;  3IN7 A;  1I3Z A;  2DCR A;  2SRC A;  5DC9 A;  1R1P A;  3IMD A;  1BLJ A;  1K9A A;  2HDX A;  1NZV A;  1X6C A;  2SHP A;  2HDV A;  1D1Z A;  3TL0 A;  2DLY A;  2PNA A;  1A09 A;  1O45 A;  2JYQ A;  3VRN A;  1O4K A;  1A81 A;  1OO4 A;  3N84 A;  1KC2 A;  3HHM B;  1O4E A;  1LKK A;  2MQI A;  2GSB A;  2C0T A;  2MRJ A;  3KFJ A;  1PIC A;  1MIL A;  1O4L A;  5I6V A;  1O4F A;  3PFV A;  1YVH A;  1BG1 A;  4K11 A;  3CXL A;  4OHI A;  1P13 A;  3EAC A;  1Z3K A;  2DLZ A;  3MAZ A;  4NWG A;  3OP0 A;  2EL8 A;  4XZ0 A;  1O4D A;  2L3T A;  1R1S A;  2CIA A;  1A1C A;  1CWD L;  2C0O A;  1XA6 A;  4DGP A;  1AOT F;  5DC0 B;  5EG3 B;  1BHF A;  1YVL A;  4EY0 A;  1O41 A;  1D4W A;  1JYU A;  3HCK A;  4ROJ A;  3S8N A;  1FHS A;  2PTK A;  1O46 A;  2VIF A;  1X27 A;  1NZL A;  1AYD A;  1KA6 A;  1SHB A;  1O44 A;  1GHU A;  2EYV A;  1NRV A;  4EIH A;  3GXW A;  1A08 A;  3VRQ A;  1F2F A;  2ABL A;  5EHR A;  5DF6 A;  3OB1 B;  4GL9 E;  3S8L A;  2L6K A;  5GJH A;  1MW4 A;  1O48 A;  1UUS A;  3T04 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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