2CRHA

Solution structure of the sh2 domain of human proto-oncogene protein vav1
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
138
structure length
138
Chain Sequence
GSSGSSGKAEAEQNWWEGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the SH2 domain of human proto-oncogene protein VAV1
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Vav proto-oncogene
total genus 16
structure length 138
sequence length 138
ec nomenclature
pdb deposition date 2005-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2crhA01
2HUWA 1O4PA 1IS0A 1D4TA 2AUGA 4H1OA 1WQUA 4FL2A 2CR4A 1O42A 1JYQA 2BBUA 2LQNA 2ETZA 2K79B 5I6VA 2Y3AB 2AOAA 2PLDA 2MC1A 3MXCA 2EU0A 3NHNA 1SPSA 3BUNB 1O4LA 4JGHA 3M7FA 2PTKA 1O4KA 3MXYA 1FBZA 4GL9E 3OP0A 1FHSA 3OB1B 3PSJA 1O4EA 1AOTF 1O4DA 2HDVA 2GSBA 3N84A 2LNXA 1LKKA 1O43A 2IUHA 1A09A 1JU5A 2JYQA 2DX0A 1BHHB 1GHUA 3VRZA 4X6SA 2IUIA 3TL0A 1HCTB 1A1EA 1FMKA 1JYRA 4EIHA 1K9AA 2YSXA 1O49A 2CI9A 3C7IA 2LQWA 2KK6A 2B3OA 1FYRA 1A81A 2H46E 3BKBA 3CD3A 1RPYA 3QWXX 2L6KA 1Z3KA 4TZIA 4LUDA 5IBMA 2H5KA 2YU7A 3VS6A 1QCFA 1O4CA 2RVFA 1A07A 1NZVA 3VRRA 3ZNIA 2C0OA 1CJ1A 2DM0A 1I3ZA 5AULA 3GQIB 3VS2A 4OHIA 3PJPA 2HCKA 1SPRA 1YVLA 1O4NA 2RSYA 4F5AA 1O4AA 3IMJA 1AYBA 2FCIA 1M27A 4L1BB 2K7AB 1O45A 3PQZA 3KFJA 1O4GA 2HDXA 2SHPA 5GJHA 5BO4A 1BKMA 4NWGA 1F1WA 1OO4A 1SKJA 2EYZA 3HIZB 2IUGA 1TZEE 4GWFA 4E93A 2MRKA 3N8MA 2EKXA 1Y57A 2EO6A 5DC0B 2IZVA 1LUKA 3K2MA 1YVHA 1O4FA 2LNWA 1BM2A 1HCSB 2MQIA 3HHMB 4E68A 1LCJA 5EHPA 1X6CA 2DLYA 1P13A 1O46A 3OV1A 4K2RA 3HCKA 5IBSA 1SHDA 2MK2A 3MAZA 2PNAA 1XA6A 1O4HA 3IN8A 3BUXB 2C0IA 3UYOA 2XP1A 5HKWA 5EG3B 2DCRA 1O4MA 3IMDA 5DF6A 5HKYA 4U1PA 2EOBA 5CDWA 1BLJA 3VS5A 5J3XA 1NRVA 1O4RA 1TCEA 4F59A 2PLEA 3VRPA 3BUMB 3WA4A 2CRHA 2ECDA 4OHLA 4A4BA 1O4OA 2HMHA 1BKLA 3QWYA 2OQ1A 2CS0A 3UF4A 1LUNA 1O4JA 5KAZA 1PICA 4EY0A 5DC9A 3VRNA 2DLZA 1O4IA 3VS0A 1R1QA 3VGOA 1JYUA 4LUEA 4D8KA 1MW4A 3VS7A 3GXXA 2RMXA 2OZOA 2Y1MA 1AD5A 2KNOA 1F2FA 4OHHA 1KC2A 4JE4A 5GJIA 5AXIA 1FU6A 1BHFA 1KA7A 2PNBA 2GE9A 1AOUF 2H8HA 4A4CA 3TKZA 3PSKA 3BUOB 3VS4A 1OPKA 1BHHA 4QSYA 4U17A 1O4QA 2EYYA 1KA6A 1R1SA 4P9ZA 2EL8A 1AYCA 1QG1E 1CSZA 4OHEA 2FO0A 4DGPA 1RJAA 4F5BA 2EO3A 1FU5A 2L3TA 3VS1A 3BUWB 2CIAA 2C0TA 1RQQC 3CWGA 5D0JA 1A1CA 1QADA 1LUIA 3EACA 1UURA 4P9VA 1BMBA 1A1BA 1SHBA 4M4ZA 1O48A 3EAZA 4WWQA 2CBLA 5EELA 1IJRA 1CWEA 2QMSA 1BF5A 1BFIA 1UUSA 4FBNA 4OHDA 1H9OA 1O47A 1LKLA 3VRQA 4FL3A 2L4KA 3PLFB 4GPLB 2ABLA 2VIFA 1O4BA 3US4A 1KSWA 4XZ0A 1M61A 3N7YA 1ZFPE 1A08A 4NWFA 3CXLA 5DC4A 1JWOA 1OO3A 1D4WA 1OPLA 3IN7A 3VROA 1AYDA 1O44A 2LCTA 4H34A 1A1AA 3S9KA 3GXWA 4K11A 1FBVA 5HKZA 1R1PA 3OB2B 4K45A 3PS5A 1SHAA 2SRCA 4DGXA 3CBLA 2MRJA 3OVEA 2RORA 3T04A 2DVJA 1BLKA 1Y1UA 2Y1NA 2CI8A 4ROJA 3VRYA 2AOBA 3VS3A 1MILA 1CSYA 1LUMA 1BFJA 1G83A 2C9WA 1D1ZA 3S8LA 1AYAA 4K44A 5EHRA 1X0NA 2EYVA 1O41A 1CWDL 3S8OA 1LCKA 1AB2A 1X27A 3PFVA 1BG1A 3S8NA 4XZ1A 4JEGA 1B47A 1NZLA 5EEQA 1GRIA
chains in the Genus database with same CATH superfamily
2HUWA 1O4PA 1IS0A 1D4TA 2AUGA 4H1OA 1WQUA 4FL2A 2CR4A 1O42A 1JYQA 2BBUA 2LQNA 2ETZA 2K79B 5I6VA 2LRAA 2AOAA 2PLDA 2Y3AB 2MC1A 3MXCA 2EU0A 3NHNA 1SPSA 3BUNB 1O4LA 4JGHA 3M7FA 2PTKA 1O4KA 3MXYA 1FBZA 4GL9E 3OP0A 1FHSA 3OB1B 3PSJA 1O4EA 1AOTF 1O4DA 2HDVA 2GSBA 3N84A 2LNXA 1LKKA 1O43A 2IUHA 1A09A 1JU5A 2JYQA 2DX0A 1BHHB 1GHUA 3VRZA 3K2TA 4X6SA 2IUIA 3TL0A 1HCTB 1A1EA 1FMKA 1JYRA 4EIHA 1K9AA 2YSXA 1O49A 2CI9A 3C7IA 2LQWA 2KK6A 2B3OA 1FYRA 1A81A 2H46E 3BKBA 3CD3A 1RPYA 3QWXX 2L6KA 1Z3KA 4TZIA 4LUDA 5IBMA 2H5KA 2YU7A 3VS6A 1QCFA 1O4CA 2RVFA 1A07A 1NZVA 3VRRA 3ZNIA 2C0OA 1CJ1A 2DM0A 1I3ZA 5AULA 3GQIB 3VS2A 4OHIA 3PJPA 3LYVA 2HCKA 1SPRA 1YVLA 1O4NA 2RSYA 4F5AA 1O4AA 3IMJA 1AYBA 2FCIA 1M27A 4L1BB 2K7AB 1O45A 3PQZA 3KFJA 1O4GA 2HDXA 2SHPA 5GJHA 5BO4A 1BKMA 4NWGA 1F1WA 1OO4A 1SKJA 2EYZA 3HIZB 2IUGA 1TZEE 4GWFA 4E93A 2MRKA 3N8MA 2EKXA 1Y57A 2EO6A 5DC0B 2KGYA 2IZVA 1LUKA 3K2MA 1YVHA 1O4FA 2LNWA 1BM2A 1HCSB 2MQIA 3HHMB 4E68A 1LCJA 5EHPA 1X6CA 2DLYA 1P13A 1O46A 3OV1A 4K2RA 3HCKA 5IBSA 1SHDA 2MK2A 3MAZA 2PNAA 1XA6A 1O4HA 3IN8A 3BUXB 2C0IA 3UYOA 2XP1A 5HKWA 5EG3B 2DCRA 1O4MA 3IMDA 5DF6A 5HKYA 4U1PA 2EOBA 5CDWA 1BLJA 3VS5A 5J3XA 1NRVA 1O4RA 1TCEA 4F59A 2PLEA 3VRPA 3BUMB 3WA4A 2CRHA 2ECDA 4OHLA 4A4BA 1O4OA 2HMHA 1BKLA 3QWYA 2OQ1A 2CS0A 3UF4A 1LUNA 1O4JA 5KAZA 1PICA 4EY0A 5DC9A 3VRNA 2DLZA 1O4IA 3VS0A 1R1QA 3VGOA 1JYUA 4LUEA 4D8KA 1MW4A 3VS7A 3GXXA 2RMXA 2OZOA 2Y1MA 1AD5A 2KNOA 1F2FA 4OHHA 1KC2A 4JE4A 5GJIA 5AXIA 1FU6A 1BHFA 1KA7A 2PNBA 2GE9A 1AOUF 2H8HA 4A4CA 3TKZA 3PSKA 3BUOB 3VS4A 1OPKA 1BHHA 4QSYA 4U17A 1O4QA 2EYYA 1KA6A 1R1SA 4P9ZA 2EL8A 1AYCA 1QG1E 1CSZA 4OHEA 2FO0A 4DGPA 1RJAA 4F5BA 2EO3A 1FU5A 2L3TA 3VS1A 3BUWB 2CIAA 2C0TA 1RQQC 3CWGA 5D0JA 1A1CA 1QADA 1LUIA 3EACA 1UURA 4P9VA 1BMBA 1A1BA 1SHBA 4M4ZA 1O48A 3EAZA 4WWQA 2CBLA 5EELA 1IJRA 1CWEA 2QMSA 1BF5A 1BFIA 1UUSA 4FBNA 4OHDA 1H9OA 1O47A 1LKLA 3VRQA 4FL3A 2L4KA 3PLFB 4GPLB 2ABLA 2VIFA 1O4BA 3US4A 1KSWA 4XZ0A 1M61A 3N7YA 1ZFPE 1A08A 4NWFA 3CXLA 5DC4A 1JWOA 1OO3A 1D4WA 1OPLA 3IN7A 3VROA 1AYDA 1O44A 2LCTA 4H34A 1A1AA 3S9KA 3GXWA 4K11A 1FBVA 5HKZA 1R1PA 3OB2B 4K45A 3PS5A 1SHAA 2SRCA 4DGXA 3CBLA 2MRJA 3OVEA 2RORA 3T04A 2DVJA 1BLKA 1Y1UA 2Y1NA 2CI8A 4ROJA 3VRYA 2AOBA 3VS3A 1MILA 1CSYA 1LUMA 1BFJA 1G83A 2C9WA 1D1ZA 3S8LA 1AYAA 4K44A 5EHRA 1X0NA 2EYVA 1O41A 1CWDL 3S8OA 1LCKA 1AB2A 1X27A 3PFVA 1BG1A 3S8NA 4XZ1A 4JEGA 1B47A 1NZLA 5EEQA 1GRIA
chains in the Genus database with same CATH topology
2HUWA 1O4PA 1IS0A 1D4TA 2AUGA 4H1OA 1WQUA 4FL2A 2CR4A 1O42A 1JYQA 2BBUA 2LQNA 2ETZA 2K79B 5I6VA 2Y3AB 2AOAA 2PLDA 2MC1A 3MXCA 2EU0A 3NHNA 1SPSA 3BUNB 1O4LA 4JGHA 3M7FA 2PTKA 1O4KA 3MXYA 1FBZA 4GL9E 3OP0A 1FHSA 3OB1B 3PSJA 1O4EA 1AOTF 1O4DA 2HDVA 2GSBA 3N84A 2LNXA 1LKKA 1O43A 2IUHA 1A09A 1JU5A 2JYQA 2DX0A 1BHHB 1GHUA 3VRZA 4X6SA 2IUIA 3TL0A 1HCTB 1A1EA 1FMKA 1JYRA 4EIHA 1K9AA 2YSXA 1O49A 2CI9A 3C7IA 2LQWA 2KK6A 2B3OA 1FYRA 1A81A 2H46E 3BKBA 3CD3A 1RPYA 3QWXX 2L6KA 1Z3KA 4TZIA 4LUDA 5IBMA 2H5KA 2YU7A 3VS6A 1QCFA 1O4CA 2RVFA 1A07A 1NZVA 3VRRA 3ZNIA 2C0OA 1CJ1A 2DM0A 1I3ZA 5AULA 3GQIB 3VS2A 4OHIA 3PJPA 2HCKA 1SPRA 1YVLA 1O4NA 2RSYA 4F5AA 1O4AA 3IMJA 1AYBA 2FCIA 1M27A 4L1BB 2K7AB 1O45A 3PQZA 3KFJA 1O4GA 2HDXA 2SHPA 5GJHA 5BO4A 1BKMA 4NWGA 1F1WA 1OO4A 1SKJA 2EYZA 3HIZB 2IUGA 1TZEE 4GWFA 4E93A 2MRKA 3N8MA 2EKXA 1Y57A 2EO6A 5DC0B 2IZVA 1LUKA 3K2MA 1YVHA 1O4FA 2LNWA 1BM2A 1HCSB 2MQIA 3HHMB 4E68A 1LCJA 5EHPA 1X6CA 2DLYA 1P13A 1O46A 3OV1A 4K2RA 3HCKA 5IBSA 1SHDA 2MK2A 3MAZA 2PNAA 1XA6A 1O4HA 3IN8A 3BUXB 2C0IA 3UYOA 2XP1A 5HKWA 5EG3B 2DCRA 1O4MA 3IMDA 5DF6A 5HKYA 4U1PA 2EOBA 5CDWA 1BLJA 3VS5A 5J3XA 1NRVA 1O4RA 1TCEA 4F59A 2PLEA 3VRPA 3BUMB 3WA4A 2CRHA 2ECDA 4OHLA 4A4BA 1O4OA 2HMHA 1BKLA 3QWYA 2OQ1A 2CS0A 3UF4A 1LUNA 1O4JA 5KAZA 1PICA 4EY0A 5DC9A 3VRNA 2DLZA 1O4IA 3VS0A 1R1QA 3VGOA 1JYUA 4LUEA 4D8KA 1MW4A 3VS7A 3GXXA 2RMXA 2OZOA 2Y1MA 1AD5A 2KNOA 1F2FA 4OHHA 1KC2A 4JE4A 5GJIA 5AXIA 1FU6A 1BHFA 1KA7A 2PNBA 2GE9A 1AOUF 2H8HA 4A4CA 3TKZA 3PSKA 3BUOB 3VS4A 1OPKA 1BHHA 4QSYA 4U17A 1O4QA 2EYYA 1KA6A 1R1SA 4P9ZA 2EL8A 1AYCA 1QG1E 1CSZA 4OHEA 2FO0A 4DGPA 1RJAA 4F5BA 2EO3A 1FU5A 2L3TA 3VS1A 3BUWB 2CIAA 2C0TA 1RQQC 3CWGA 5D0JA 1A1CA 1QADA 1LUIA 3EACA 1UURA 4P9VA 1BMBA 1A1BA 1SHBA 4M4ZA 1O48A 3EAZA 4WWQA 2CBLA 5EELA 1IJRA 1CWEA 2QMSA 1BF5A 1BFIA 1UUSA 4FBNA 4OHDA 1H9OA 1O47A 1LKLA 3VRQA 4FL3A 2L4KA 3PLFB 4GPLB 2ABLA 2VIFA 1O4BA 3US4A 1KSWA 4XZ0A 1M61A 3N7YA 1ZFPE 1A08A 4NWFA 3CXLA 5DC4A 1JWOA 1OO3A 1D4WA 1OPLA 3IN7A 3VROA 1AYDA 1O44A 2LCTA 4H34A 1A1AA 3S9KA 3GXWA 4K11A 1FBVA 5HKZA 1R1PA 3OB2B 4K45A 3PS5A 1SHAA 2SRCA 4DGXA 3CBLA 2MRJA 3OVEA 2RORA 3T04A 2DVJA 1BLKA 1Y1UA 2Y1NA 2CI8A 4ROJA 3VRYA 2AOBA 3VS3A 1MILA 1CSYA 1LUMA 1BFJA 1G83A 2C9WA 1D1ZA 3S8LA 1AYAA 4K44A 5EHRA 1X0NA 2EYVA 1O41A 1CWDL 3S8OA 1LCKA 1AB2A 1X27A 3PFVA 1BG1A 3S8NA 4XZ1A 4JEGA 1B47A 1NZLA 5EEQA 1GRIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HUW A;  1O4P A;  1IS0 A;  1D4T A;  2AUG A;  4H1O A;  1WQU A;  4FL2 A;  2CR4 A;  1O42 A;  1JYQ A;  2BBU A;  2LQN A;  2ETZ A;  2K79 B;  5I6V A;  2Y3A B;  2AOA A;  2PLD A;  2MC1 A;  3MXC A;  2EU0 A;  3NHN A;  1SPS A;  3BUN B;  1O4L A;  4JGH A;  3M7F A;  2PTK A;  1O4K A;  3MXY A;  1FBZ A;  4GL9 E;  3OP0 A;  1FHS A;  3OB1 B;  3PSJ A;  1O4E A;  1AOT F;  1O4D A;  2HDV A;  2GSB A;  3N84 A;  2LNX A;  1LKK A;  1O43 A;  2IUH A;  1A09 A;  1JU5 A;  2JYQ A;  2DX0 A;  1BHH B;  1GHU A;  3VRZ A;  4X6S A;  2IUI A;  3TL0 A;  1HCT B;  1A1E A;  1FMK A;  1JYR A;  4EIH A;  1K9A A;  2YSX A;  1O49 A;  2CI9 A;  3C7I A;  2LQW A;  2KK6 A;  2B3O A;  1FYR A;  1A81 A;  2H46 E;  3BKB A;  3CD3 A;  1RPY A;  3QWX X;  2L6K A;  1Z3K A;  4TZI A;  4LUD A;  5IBM A;  2H5K A;  2YU7 A;  3VS6 A;  1QCF A;  1O4C A;  2RVF A;  1A07 A;  1NZV A;  3VRR A;  3ZNI A;  2C0O A;  1CJ1 A;  2DM0 A;  1I3Z A;  5AUL A;  3GQI B;  3VS2 A;  4OHI A;  3PJP A;  2HCK A;  1SPR A;  1YVL A;  1O4N A;  2RSY A;  4F5A A;  1O4A A;  3IMJ A;  1AYB A;  2FCI A;  1M27 A;  4L1B B;  2K7A B;  1O45 A;  3PQZ A;  3KFJ A;  1O4G A;  2HDX A;  2SHP A;  5GJH A;  5BO4 A;  1BKM A;  4NWG A;  1F1W A;  1OO4 A;  1SKJ A;  2EYZ A;  3HIZ B;  2IUG A;  1TZE E;  4GWF A;  4E93 A;  2MRK A;  3N8M A;  2EKX A;  1Y57 A;  2EO6 A;  5DC0 B;  2IZV A;  1LUK A;  3K2M A;  1YVH A;  1O4F A;  2LNW A;  1BM2 A;  1HCS B;  2MQI A;  3HHM B;  4E68 A;  1LCJ A;  5EHP A;  1X6C A;  2DLY A;  1P13 A;  1O46 A;  3OV1 A;  4K2R A;  3HCK A;  5IBS A;  1SHD A;  2MK2 A;  3MAZ A;  2PNA A;  1XA6 A;  1O4H A;  3IN8 A;  3BUX B;  2C0I A;  3UYO A;  2XP1 A;  5HKW A;  5EG3 B;  2DCR A;  1O4M A;  3IMD A;  5DF6 A;  5HKY A;  4U1P A;  2EOB A;  5CDW A;  1BLJ A;  3VS5 A;  5J3X A;  1NRV A;  1O4R A;  1TCE A;  4F59 A;  2PLE A;  3VRP A;  3BUM B;  3WA4 A;  2CRH A;  2ECD A;  4OHL A;  4A4B A;  1O4O A;  2HMH A;  1BKL A;  3QWY A;  2OQ1 A;  2CS0 A;  3UF4 A;  1LUN A;  1O4J A;  5KAZ A;  1PIC A;  4EY0 A;  5DC9 A;  3VRN A;  2DLZ A;  1O4I A;  3VS0 A;  1R1Q A;  3VGO A;  1JYU A;  4LUE A;  4D8K A;  1MW4 A;  3VS7 A;  3GXX A;  2RMX A;  2OZO A;  2Y1M A;  1AD5 A;  2KNO A;  1F2F A;  4OHH A;  1KC2 A;  4JE4 A;  5GJI A;  5AXI A;  1FU6 A;  1BHF A;  1KA7 A;  2PNB A;  2GE9 A;  1AOU F;  2H8H A;  4A4C A;  3TKZ A;  3PSK A;  3BUO B;  3VS4 A;  1OPK A;  1BHH A;  4QSY A;  4U17 A;  1O4Q A;  2EYY A;  1KA6 A;  1R1S A;  4P9Z A;  2EL8 A;  1AYC A;  1QG1 E;  1CSZ A;  4OHE A;  2FO0 A;  4DGP A;  1RJA A;  4F5B A;  2EO3 A;  1FU5 A;  2L3T A;  3VS1 A;  3BUW B;  2CIA A;  2C0T A;  1RQQ C;  3CWG A;  5D0J A;  1A1C A;  1QAD A;  1LUI A;  3EAC A;  1UUR A;  4P9V A;  1BMB A;  1A1B A;  1SHB A;  4M4Z A;  1O48 A;  3EAZ A;  4WWQ A;  2CBL A;  5EEL A;  1IJR A;  1CWE A;  2QMS A;  1BF5 A;  1BFI A;  1UUS A;  4FBN A;  4OHD A;  1H9O A;  1O47 A;  1LKL A;  3VRQ A;  4FL3 A;  2L4K A;  3PLF B;  4GPL B;  2ABL A;  2VIF A;  1O4B A;  3US4 A;  1KSW A;  4XZ0 A;  1M61 A;  3N7Y A;  1ZFP E;  1A08 A;  4NWF A;  3CXL A;  5DC4 A;  1JWO A;  1OO3 A;  1D4W A;  1OPL A;  3IN7 A;  3VRO A;  1AYD A;  1O44 A;  2LCT A;  4H34 A;  1A1A A;  3S9K A;  3GXW A;  4K11 A;  1FBV A;  5HKZ A;  1R1P A;  3OB2 B;  4K45 A;  3PS5 A;  1SHA A;  2SRC A;  4DGX A;  3CBL A;  2MRJ A;  3OVE A;  2ROR A;  3T04 A;  2DVJ A;  1BLK A;  1Y1U A;  2Y1N A;  2CI8 A;  4ROJ A;  3VRY A;  2AOB A;  3VS3 A;  1MIL A;  1CSY A;  1LUM A;  1BFJ A;  1G83 A;  2C9W A;  1D1Z A;  3S8L A;  1AYA A;  4K44 A;  5EHR A;  1X0N A;  2EYV A;  1O41 A;  1CWD L;  3S8O A;  1LCK A;  1AB2 A;  1X27 A;  3PFV A;  1BG1 A;  3S8N A;  4XZ1 A;  4JEG A;  1B47 A;  1NZL A;  5EEQ A;  1GRI A; 
#chains in the Genus database with same CATH topology
 2HUW A;  1O4P A;  1IS0 A;  1D4T A;  2AUG A;  4H1O A;  1WQU A;  4FL2 A;  2CR4 A;  1O42 A;  1JYQ A;  2BBU A;  2LQN A;  2ETZ A;  2K79 B;  5I6V A;  2LRA A;  2AOA A;  2PLD A;  2Y3A B;  2MC1 A;  3MXC A;  2EU0 A;  3NHN A;  1SPS A;  3BUN B;  1O4L A;  4JGH A;  3M7F A;  2PTK A;  1O4K A;  3MXY A;  1FBZ A;  4GL9 E;  3OP0 A;  1FHS A;  3OB1 B;  3PSJ A;  1O4E A;  1AOT F;  1O4D A;  2HDV A;  2GSB A;  3N84 A;  2LNX A;  1LKK A;  1O43 A;  2IUH A;  1A09 A;  1JU5 A;  2JYQ A;  2DX0 A;  1BHH B;  1GHU A;  3VRZ A;  3K2T A;  4X6S A;  2IUI A;  3TL0 A;  1HCT B;  1A1E A;  1FMK A;  1JYR A;  4EIH A;  1K9A A;  2YSX A;  1O49 A;  2CI9 A;  3C7I A;  2LQW A;  2KK6 A;  2B3O A;  1FYR A;  1A81 A;  2H46 E;  3BKB A;  3CD3 A;  1RPY A;  3QWX X;  2L6K A;  1Z3K A;  4TZI A;  4LUD A;  5IBM A;  2H5K A;  2YU7 A;  3VS6 A;  1QCF A;  1O4C A;  2RVF A;  1A07 A;  1NZV A;  3VRR A;  3ZNI A;  2C0O A;  1CJ1 A;  2DM0 A;  1I3Z A;  5AUL A;  3GQI B;  3VS2 A;  4OHI A;  3PJP A;  3LYV A;  2HCK A;  1SPR A;  1YVL A;  1O4N A;  2RSY A;  4F5A A;  1O4A A;  3IMJ A;  1AYB A;  2FCI A;  1M27 A;  4L1B B;  2K7A B;  1O45 A;  3PQZ A;  3KFJ A;  1O4G A;  2HDX A;  2SHP A;  5GJH A;  5BO4 A;  1BKM A;  4NWG A;  1F1W A;  1OO4 A;  1SKJ A;  2EYZ A;  3HIZ B;  2IUG A;  1TZE E;  4GWF A;  4E93 A;  2MRK A;  3N8M A;  2EKX A;  1Y57 A;  2EO6 A;  5DC0 B;  2KGY A;  2IZV A;  1LUK A;  3K2M A;  1YVH A;  1O4F A;  2LNW A;  1BM2 A;  1HCS B;  2MQI A;  3HHM B;  4E68 A;  1LCJ A;  5EHP A;  1X6C A;  2DLY A;  1P13 A;  1O46 A;  3OV1 A;  4K2R A;  3HCK A;  5IBS A;  1SHD A;  2MK2 A;  3MAZ A;  2PNA A;  1XA6 A;  1O4H A;  3IN8 A;  3BUX B;  2C0I A;  3UYO A;  2XP1 A;  5HKW A;  5EG3 B;  2DCR A;  1O4M A;  3IMD A;  5DF6 A;  5HKY A;  4U1P A;  2EOB A;  5CDW A;  1BLJ A;  3VS5 A;  5J3X A;  1NRV A;  1O4R A;  1TCE A;  4F59 A;  2PLE A;  3VRP A;  3BUM B;  3WA4 A;  2CRH A;  2ECD A;  4OHL A;  4A4B A;  1O4O A;  2HMH A;  1BKL A;  3QWY A;  2OQ1 A;  2CS0 A;  3UF4 A;  1LUN A;  1O4J A;  5KAZ A;  1PIC A;  4EY0 A;  5DC9 A;  3VRN A;  2DLZ A;  1O4I A;  3VS0 A;  1R1Q A;  3VGO A;  1JYU A;  4LUE A;  4D8K A;  1MW4 A;  3VS7 A;  3GXX A;  2RMX A;  2OZO A;  2Y1M A;  1AD5 A;  2KNO A;  1F2F A;  4OHH A;  1KC2 A;  4JE4 A;  5GJI A;  5AXI A;  1FU6 A;  1BHF A;  1KA7 A;  2PNB A;  2GE9 A;  1AOU F;  2H8H A;  4A4C A;  3TKZ A;  3PSK A;  3BUO B;  3VS4 A;  1OPK A;  1BHH A;  4QSY A;  4U17 A;  1O4Q A;  2EYY A;  1KA6 A;  1R1S A;  4P9Z A;  2EL8 A;  1AYC A;  1QG1 E;  1CSZ A;  4OHE A;  2FO0 A;  4DGP A;  1RJA A;  4F5B A;  2EO3 A;  1FU5 A;  2L3T A;  3VS1 A;  3BUW B;  2CIA A;  2C0T A;  1RQQ C;  3CWG A;  5D0J A;  1A1C A;  1QAD A;  1LUI A;  3EAC A;  1UUR A;  4P9V A;  1BMB A;  1A1B A;  1SHB A;  4M4Z A;  1O48 A;  3EAZ A;  4WWQ A;  2CBL A;  5EEL A;  1IJR A;  1CWE A;  2QMS A;  1BF5 A;  1BFI A;  1UUS A;  4FBN A;  4OHD A;  1H9O A;  1O47 A;  1LKL A;  3VRQ A;  4FL3 A;  2L4K A;  3PLF B;  4GPL B;  2ABL A;  2VIF A;  1O4B A;  3US4 A;  1KSW A;  4XZ0 A;  1M61 A;  3N7Y A;  1ZFP E;  1A08 A;  4NWF A;  3CXL A;  5DC4 A;  1JWO A;  1OO3 A;  1D4W A;  1OPL A;  3IN7 A;  3VRO A;  1AYD A;  1O44 A;  2LCT A;  4H34 A;  1A1A A;  3S9K A;  3GXW A;  4K11 A;  1FBV A;  5HKZ A;  1R1P A;  3OB2 B;  4K45 A;  3PS5 A;  1SHA A;  2SRC A;  4DGX A;  3CBL A;  2MRJ A;  3OVE A;  2ROR A;  3T04 A;  2DVJ A;  1BLK A;  1Y1U A;  2Y1N A;  2CI8 A;  4ROJ A;  3VRY A;  2AOB A;  3VS3 A;  1MIL A;  1CSY A;  1LUM A;  1BFJ A;  1G83 A;  2C9W A;  1D1Z A;  3S8L A;  1AYA A;  4K44 A;  5EHR A;  1X0N A;  2EYV A;  1O41 A;  1CWD L;  3S8O A;  1LCK A;  1AB2 A;  1X27 A;  3PFV A;  1BG1 A;  3S8N A;  4XZ1 A;  4JEG A;  1B47 A;  1NZL A;  5EEQ A;  1GRI A; 
#chains in the Genus database with same CATH homology
 2HUW A;  1O4P A;  1IS0 A;  1D4T A;  2AUG A;  4H1O A;  1WQU A;  4FL2 A;  2CR4 A;  1O42 A;  1JYQ A;  2BBU A;  2LQN A;  2ETZ A;  2K79 B;  5I6V A;  2Y3A B;  2AOA A;  2PLD A;  2MC1 A;  3MXC A;  2EU0 A;  3NHN A;  1SPS A;  3BUN B;  1O4L A;  4JGH A;  3M7F A;  2PTK A;  1O4K A;  3MXY A;  1FBZ A;  4GL9 E;  3OP0 A;  1FHS A;  3OB1 B;  3PSJ A;  1O4E A;  1AOT F;  1O4D A;  2HDV A;  2GSB A;  3N84 A;  2LNX A;  1LKK A;  1O43 A;  2IUH A;  1A09 A;  1JU5 A;  2JYQ A;  2DX0 A;  1BHH B;  1GHU A;  3VRZ A;  4X6S A;  2IUI A;  3TL0 A;  1HCT B;  1A1E A;  1FMK A;  1JYR A;  4EIH A;  1K9A A;  2YSX A;  1O49 A;  2CI9 A;  3C7I A;  2LQW A;  2KK6 A;  2B3O A;  1FYR A;  1A81 A;  2H46 E;  3BKB A;  3CD3 A;  1RPY A;  3QWX X;  2L6K A;  1Z3K A;  4TZI A;  4LUD A;  5IBM A;  2H5K A;  2YU7 A;  3VS6 A;  1QCF A;  1O4C A;  2RVF A;  1A07 A;  1NZV A;  3VRR A;  3ZNI A;  2C0O A;  1CJ1 A;  2DM0 A;  1I3Z A;  5AUL A;  3GQI B;  3VS2 A;  4OHI A;  3PJP A;  2HCK A;  1SPR A;  1YVL A;  1O4N A;  2RSY A;  4F5A A;  1O4A A;  3IMJ A;  1AYB A;  2FCI A;  1M27 A;  4L1B B;  2K7A B;  1O45 A;  3PQZ A;  3KFJ A;  1O4G A;  2HDX A;  2SHP A;  5GJH A;  5BO4 A;  1BKM A;  4NWG A;  1F1W A;  1OO4 A;  1SKJ A;  2EYZ A;  3HIZ B;  2IUG A;  1TZE E;  4GWF A;  4E93 A;  2MRK A;  3N8M A;  2EKX A;  1Y57 A;  2EO6 A;  5DC0 B;  2IZV A;  1LUK A;  3K2M A;  1YVH A;  1O4F A;  2LNW A;  1BM2 A;  1HCS B;  2MQI A;  3HHM B;  4E68 A;  1LCJ A;  5EHP A;  1X6C A;  2DLY A;  1P13 A;  1O46 A;  3OV1 A;  4K2R A;  3HCK A;  5IBS A;  1SHD A;  2MK2 A;  3MAZ A;  2PNA A;  1XA6 A;  1O4H A;  3IN8 A;  3BUX B;  2C0I A;  3UYO A;  2XP1 A;  5HKW A;  5EG3 B;  2DCR A;  1O4M A;  3IMD A;  5DF6 A;  5HKY A;  4U1P A;  2EOB A;  5CDW A;  1BLJ A;  3VS5 A;  5J3X A;  1NRV A;  1O4R A;  1TCE A;  4F59 A;  2PLE A;  3VRP A;  3BUM B;  3WA4 A;  2CRH A;  2ECD A;  4OHL A;  4A4B A;  1O4O A;  2HMH A;  1BKL A;  3QWY A;  2OQ1 A;  2CS0 A;  3UF4 A;  1LUN A;  1O4J A;  5KAZ A;  1PIC A;  4EY0 A;  5DC9 A;  3VRN A;  2DLZ A;  1O4I A;  3VS0 A;  1R1Q A;  3VGO A;  1JYU A;  4LUE A;  4D8K A;  1MW4 A;  3VS7 A;  3GXX A;  2RMX A;  2OZO A;  2Y1M A;  1AD5 A;  2KNO A;  1F2F A;  4OHH A;  1KC2 A;  4JE4 A;  5GJI A;  5AXI A;  1FU6 A;  1BHF A;  1KA7 A;  2PNB A;  2GE9 A;  1AOU F;  2H8H A;  4A4C A;  3TKZ A;  3PSK A;  3BUO B;  3VS4 A;  1OPK A;  1BHH A;  4QSY A;  4U17 A;  1O4Q A;  2EYY A;  1KA6 A;  1R1S A;  4P9Z A;  2EL8 A;  1AYC A;  1QG1 E;  1CSZ A;  4OHE A;  2FO0 A;  4DGP A;  1RJA A;  4F5B A;  2EO3 A;  1FU5 A;  2L3T A;  3VS1 A;  3BUW B;  2CIA A;  2C0T A;  1RQQ C;  3CWG A;  5D0J A;  1A1C A;  1QAD A;  1LUI A;  3EAC A;  1UUR A;  4P9V A;  1BMB A;  1A1B A;  1SHB A;  4M4Z A;  1O48 A;  3EAZ A;  4WWQ A;  2CBL A;  5EEL A;  1IJR A;  1CWE A;  2QMS A;  1BF5 A;  1BFI A;  1UUS A;  4FBN A;  4OHD A;  1H9O A;  1O47 A;  1LKL A;  3VRQ A;  4FL3 A;  2L4K A;  3PLF B;  4GPL B;  2ABL A;  2VIF A;  1O4B A;  3US4 A;  1KSW A;  4XZ0 A;  1M61 A;  3N7Y A;  1ZFP E;  1A08 A;  4NWF A;  3CXL A;  5DC4 A;  1JWO A;  1OO3 A;  1D4W A;  1OPL A;  3IN7 A;  3VRO A;  1AYD A;  1O44 A;  2LCT A;  4H34 A;  1A1A A;  3S9K A;  3GXW A;  4K11 A;  1FBV A;  5HKZ A;  1R1P A;  3OB2 B;  4K45 A;  3PS5 A;  1SHA A;  2SRC A;  4DGX A;  3CBL A;  2MRJ A;  3OVE A;  2ROR A;  3T04 A;  2DVJ A;  1BLK A;  1Y1U A;  2Y1N A;  2CI8 A;  4ROJ A;  3VRY A;  2AOB A;  3VS3 A;  1MIL A;  1CSY A;  1LUM A;  1BFJ A;  1G83 A;  2C9W A;  1D1Z A;  3S8L A;  1AYA A;  4K44 A;  5EHR A;  1X0N A;  2EYV A;  1O41 A;  1CWD L;  3S8O A;  1LCK A;  1AB2 A;  1X27 A;  3PFV A;  1BG1 A;  3S8N A;  4XZ1 A;  4JEG A;  1B47 A;  1NZL A;  5EEQ A;  1GRI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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