The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
225
|
sequence length |
682
|
structure length |
652
|
Chain Sequence |
SQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural bases of unphosphorylated STAT1 association and receptor binding.
pubmed doi rcsb |
| molecule tags |
Signaling protein
|
| source organism |
Homo sapiens
|
| molecule keywords |
Signal transducer and activator of transcription 1-alpha/bet
|
| total genus |
225
|
| structure length |
652
|
| sequence length |
682
|
| chains with identical sequence |
B
|
| ec nomenclature | |
| pdb deposition date | 2005-02-16 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00017 | SH2 | SH2 domain |
| A | PF01017 | STAT_alpha | STAT protein, all-alpha domain |
| A | PF02864 | STAT_bind | STAT protein, DNA binding domain |
| A | PF02865 | STAT_int | STAT protein, protein interaction domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Recoverin; domain 1 | EF-hand | ||
| Mainly Alpha | Orthogonal Bundle | Transcription Factor, Stat-4 | STAT transcription factor, N-terminal domain | ||
| Mainly Alpha | Up-down Bundle | Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 | Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
| Alpha Beta | 2-Layer Sandwich | SHC Adaptor Protein | SH2 domain |
