1SPRA

Binding of a high affinity phosphotyrosyl peptide to the src sh2 domain: crystal structures of the complexed and peptide-free forms
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
103
structure length
103
Chain Sequence
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
pubmed doi rcsb
molecule tags Transferase(phosphotransferase)
source organism Rous sarcoma virus
molecule keywords SRC TYROSINE KINASE SH2 DOMAIN
total genus 24
structure length 103
sequence length 103
chains with identical sequence B, C, D
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1993-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1sprA00
2PTKA 3CD3A 4NWGA 5EHRA 4GPLB 2CI8A 2ABLA 1MILA 3BUNB 2MK2A 4EIHA 3PJPA 4K45A 3VS5A 5J3XA 1O4FA 5HKWA 1JWOA 2MRJA 1CJ1A 3MXYA 1M61A 5HKYA 3QWXX 1KC2A 2PLEA 4U17A 4A4BA 1X27A 1CSZA 4NWFA 1A08A 1O47A 3VRPA 3IMDA 1BLJA 4OHEA 1BHHB 4JE4A 1O4IA 3BKBA 1O44A 1CSYA 1A1CA 3WA4A 2HCKA 3VRZA 3PSKA 3S8NA 2YU7A 1ZFPE 1JYQA 1O4PA 3GXXA 5AXIA 1O4GA 1OO4A 2LNXA 2HUWA 2FO0A 3PSJA 1O4QA 2RSYA 3N84A 3VS7A 3IN8A 3T04A 2YSXA 1SHDA 2BBUA 2IUGA 1LUKA 3VS6A 1WQUA 3EAZA 2LCTA 1G83A 2GSBA 2H46E 2PLDA 1P13A 2L6KA 2DLYA 2MC1A 1NRVA 4FBNA 1AOUF 1O48A 1YVHA 3NHNA 4JGHA 1KSWA 1QG1E 1O4HA 5DC0B 4LUDA 3VROA 3PFVA 3CXLA 5IBSA 1F2FA 1RQQC 4F5AA 1BHHA 1LCKA 2EL8A 1SPSA 1FBVA 1BG1A 1LKKA 2H5KA 4OHDA 1B47A 1H9OA 1TZEE 2XP1A 1IJRA 1SPRA 3QWYA 3VRQA 3M7FA 3K2MA 1FU6A 1O49A 5DF6A 5HKZA 1LUNA 1O4CA 2C0OA 1O4KA 3OB1B 2CS0A 3VS2A 2DX0A 2IUHA 4OHIA 1AOTF 2AOAA 3OB2B 5EEQA 2PNAA 1BF5A 3UF4A 1BHFA 2KK6A 2RORA 2PNBA 2C0TA 1JYUA 1O4JA 2MQIA 5AULA 3N8MA 4LUEA 1HCTB 1O4NA 2LQWA 1FU5A 1AB2A 3PS5A 3OVEA 2KNOA 1BKMA 1GRIA 1O4RA 2H8HA 1QADA 5BO4A 1LCJA 1O42A 1R1QA 4K11A 3IMJA 1BKLA 1FMKA 3BUOB 1O46A 1BFJA 2DCRA 1O4AA 5DC9A 1FHSA 3VS4A 2AOBA 4M4ZA 3OV1A 1SKJA 1O4MA 2L3TA 1AYAA 1SHBA 5D0JA 5EELA 2EYYA 2OQ1A 2MRKA 2EYZA 3VGOA 1AYBA 1SHAA 3S8LA 1LKLA 2CBLA 1CWDL 1OPLA 2C0IA 1O4LA 4OHLA 1A1EA 1KA7A 2CR4A 2IZVA 1QCFA 3VRRA 4DGPA 1NZVA 4XZ1A 5CDWA 3UYOA 3BUXB 4OHHA 2CRHA 1A09A 4GL9E 1MW4A 1Y57A 3KFJA 1XA6A 4H34A 1K9AA 1OPKA 1O4DA 2LNWA 3CBLA 1X6CA 2HMHA 1BFIA 1GHUA 4FL3A 4EY0A 4K44A 1LUMA 2CI9A 1A81A 5GJIA 1O41A 3HHMB 3S9KA 3BUWB 3GXWA 3TL0A 2IUIA 1KA6A 2K7AB 1YVLA 3S8OA 1PICA 2DLZA 2DVJA 3VS3A 1A1BA 1O45A 4GWFA 4H1OA 1O43A 4P9ZA 1R1SA 3HIZB 1FBZA 4F59A 3OP0A 3ZNIA 2ECDA 2EO3A 4DGXA 2SHPA 1OO3A 2GE9A 2SRCA 5IBMA 1UURA 2EO6A 2CIAA 1F1WA 1TCEA 1O4OA 1BMBA 2RVFA 1RPYA 2EYVA 1JU5A 1BM2A 2ETZA 2EKXA 1IS0A 4D8KA 1X0NA 2Y3AB 2OZOA 2EU0A 2B3OA 2HDXA 4A4CA 3C7IA 4U1PA 2AUGA 1Y1UA 3US4A 4X6SA 2HDVA 3VS1A 1A1AA 1AYDA 4ROJA 4FL2A 4WWQA 5DC4A 2Y1MA 3N7YA 5GJHA 2RMXA 3VRNA 3HCKA 2K79B 2EOBA 1JYRA 2FCIA 3MAZA 4F5BA 1O4EA 2JYQA 3CWGA 4TZIA 5I6VA 1A07A 2LQNA 4K2RA 3PQZA 1Z3KA 3MXCA 1HCSB 2QMSA 3GQIB 5KAZA 4QSYA 1FYRA 5EHPA 3PLFB 4JEGA 5EG3B 1O4BA 1BLKA 1CWEA 1R1PA 4P9VA 2L4KA 1AYCA 3IN7A 3TKZA 4E93A 2VIFA 1RJAA 1D4TA 3BUMB 1D4WA 2C9WA 4L1BB 2Y1NA 3VRYA 4E68A 1UUSA 1D1ZA 1LUIA 1NZLA 1I3ZA 1M27A 4XZ0A 2DM0A 3EACA 1AD5A 3VS0A
chains in the Genus database with same CATH superfamily
2PTKA 3CD3A 4NWGA 5EHRA 4GPLB 2CI8A 2ABLA 1MILA 3BUNB 2MK2A 4EIHA 3PJPA 4K45A 3VS5A 5J3XA 1O4FA 5HKWA 1JWOA 2MRJA 1CJ1A 3MXYA 1M61A 5HKYA 3QWXX 1KC2A 2PLEA 4U17A 4A4BA 1X27A 1CSZA 4NWFA 1A08A 1O47A 3VRPA 3IMDA 1BLJA 4OHEA 1BHHB 4JE4A 1O4IA 3BKBA 1O44A 1CSYA 1A1CA 3WA4A 2HCKA 3VRZA 3PSKA 3S8NA 2YU7A 3LYVA 1ZFPE 1JYQA 1O4PA 3GXXA 5AXIA 1O4GA 1OO4A 2LNXA 2HUWA 2FO0A 3PSJA 1O4QA 2RSYA 3N84A 3VS7A 3IN8A 3T04A 2YSXA 1SHDA 2BBUA 2IUGA 1LUKA 3VS6A 1WQUA 3EAZA 2LCTA 1G83A 2GSBA 2H46E 2PLDA 1P13A 2L6KA 2DLYA 2MC1A 1NRVA 4FBNA 1AOUF 1O48A 1YVHA 3NHNA 4JGHA 1KSWA 1QG1E 1O4HA 5DC0B 4LUDA 3VROA 3PFVA 3CXLA 5IBSA 1F2FA 1RQQC 4F5AA 1BHHA 1LCKA 2EL8A 1SPSA 1FBVA 1BG1A 1LKKA 2H5KA 4OHDA 1B47A 1H9OA 1TZEE 2XP1A 1IJRA 1SPRA 3QWYA 3VRQA 3M7FA 3K2MA 1FU6A 1O49A 5DF6A 5HKZA 1LUNA 1O4CA 2C0OA 1O4KA 3OB1B 2CS0A 3VS2A 2DX0A 2IUHA 4OHIA 1AOTF 2AOAA 3OB2B 5EEQA 2PNAA 1BF5A 3UF4A 1BHFA 2KK6A 2RORA 2PNBA 2C0TA 1JYUA 1O4JA 2MQIA 5AULA 3N8MA 4LUEA 1HCTB 1O4NA 2LQWA 1FU5A 1AB2A 3PS5A 3OVEA 2KNOA 1BKMA 1GRIA 1O4RA 2H8HA 1QADA 5BO4A 1LCJA 1O42A 3K2TA 1R1QA 4K11A 3IMJA 1BKLA 1FMKA 3BUOB 1O46A 1BFJA 2DCRA 1O4AA 5DC9A 1FHSA 3VS4A 2AOBA 4M4ZA 3OV1A 1SKJA 1O4MA 2L3TA 1AYAA 1SHBA 5D0JA 5EELA 2EYYA 2OQ1A 2MRKA 2EYZA 3VGOA 1AYBA 1SHAA 3S8LA 1LKLA 2CBLA 1CWDL 1OPLA 2C0IA 1O4LA 4OHLA 1A1EA 1KA7A 2CR4A 2IZVA 1QCFA 3VRRA 4DGPA 1NZVA 4XZ1A 5CDWA 3UYOA 3BUXB 4OHHA 2CRHA 1A09A 4GL9E 2LRAA 1MW4A 1Y57A 3KFJA 1XA6A 4H34A 1K9AA 1OPKA 1O4DA 2LNWA 3CBLA 1X6CA 2HMHA 1BFIA 1GHUA 4FL3A 4EY0A 4K44A 1LUMA 2CI9A 1A81A 5GJIA 1O41A 3HHMB 3S9KA 3BUWB 3GXWA 3TL0A 2IUIA 1KA6A 2K7AB 1YVLA 3S8OA 1PICA 2DLZA 2DVJA 3VS3A 1A1BA 1O45A 4GWFA 4H1OA 1O43A 4P9ZA 1R1SA 3HIZB 1FBZA 4F59A 3OP0A 3ZNIA 2ECDA 2EO3A 4DGXA 2SHPA 1OO3A 2GE9A 2SRCA 5IBMA 1UURA 2EO6A 2CIAA 1F1WA 1TCEA 1O4OA 1BMBA 2RVFA 1RPYA 2EYVA 1JU5A 1BM2A 2ETZA 2EKXA 2KGYA 1IS0A 4D8KA 1X0NA 2Y3AB 2OZOA 2EU0A 2B3OA 2HDXA 4A4CA 3C7IA 4U1PA 2AUGA 1Y1UA 3US4A 4X6SA 2HDVA 3VS1A 1A1AA 1AYDA 4ROJA 4FL2A 4WWQA 5DC4A 2Y1MA 3N7YA 5GJHA 2RMXA 3VRNA 3HCKA 2K79B 2EOBA 1JYRA 2FCIA 3MAZA 4F5BA 1O4EA 2JYQA 3CWGA 4TZIA 5I6VA 1A07A 2LQNA 4K2RA 3PQZA 1Z3KA 3MXCA 1HCSB 2QMSA 3GQIB 5KAZA 4QSYA 1FYRA 5EHPA 3PLFB 4JEGA 5EG3B 1O4BA 1BLKA 1CWEA 1R1PA 4P9VA 2L4KA 1AYCA 3IN7A 3TKZA 4E93A 2VIFA 1RJAA 1D4TA 3BUMB 1D4WA 2C9WA 4L1BB 2Y1NA 3VRYA 4E68A 1UUSA 1D1ZA 1LUIA 1NZLA 1I3ZA 1M27A 4XZ0A 2DM0A 3EACA 1AD5A 3VS0A
chains in the Genus database with same CATH topology
2PTKA 3CD3A 4NWGA 5EHRA 4GPLB 2CI8A 2ABLA 1MILA 3BUNB 2MK2A 4EIHA 3PJPA 4K45A 3VS5A 5J3XA 1O4FA 5HKWA 1JWOA 2MRJA 1CJ1A 3MXYA 1M61A 5HKYA 3QWXX 1KC2A 2PLEA 4U17A 4A4BA 1X27A 1CSZA 4NWFA 1A08A 1O47A 3VRPA 3IMDA 1BLJA 4OHEA 1BHHB 4JE4A 1O4IA 3BKBA 1O44A 1CSYA 1A1CA 3WA4A 2HCKA 3VRZA 3PSKA 3S8NA 2YU7A 1ZFPE 1JYQA 1O4PA 3GXXA 5AXIA 1O4GA 1OO4A 2LNXA 2HUWA 2FO0A 3PSJA 1O4QA 2RSYA 3N84A 3VS7A 3IN8A 3T04A 2YSXA 1SHDA 2BBUA 2IUGA 1LUKA 3VS6A 1WQUA 3EAZA 2LCTA 1G83A 2GSBA 2H46E 2PLDA 1P13A 2L6KA 2DLYA 2MC1A 1NRVA 4FBNA 1AOUF 1O48A 1YVHA 3NHNA 4JGHA 1KSWA 1QG1E 1O4HA 5DC0B 4LUDA 3VROA 3PFVA 3CXLA 5IBSA 1F2FA 1RQQC 4F5AA 1BHHA 1LCKA 2EL8A 1SPSA 1FBVA 1BG1A 1LKKA 2H5KA 4OHDA 1B47A 1H9OA 1TZEE 2XP1A 1IJRA 1SPRA 3QWYA 3VRQA 3M7FA 3K2MA 1FU6A 1O49A 5DF6A 5HKZA 1LUNA 1O4CA 2C0OA 1O4KA 3OB1B 2CS0A 3VS2A 2DX0A 2IUHA 4OHIA 1AOTF 2AOAA 3OB2B 5EEQA 2PNAA 1BF5A 3UF4A 1BHFA 2KK6A 2RORA 2PNBA 2C0TA 1JYUA 1O4JA 2MQIA 5AULA 3N8MA 4LUEA 1HCTB 1O4NA 2LQWA 1FU5A 1AB2A 3PS5A 3OVEA 2KNOA 1BKMA 1GRIA 1O4RA 2H8HA 1QADA 5BO4A 1LCJA 1O42A 1R1QA 4K11A 3IMJA 1BKLA 1FMKA 3BUOB 1O46A 1BFJA 2DCRA 1O4AA 5DC9A 1FHSA 3VS4A 2AOBA 4M4ZA 3OV1A 1SKJA 1O4MA 2L3TA 1AYAA 1SHBA 5D0JA 5EELA 2EYYA 2OQ1A 2MRKA 2EYZA 3VGOA 1AYBA 1SHAA 3S8LA 1LKLA 2CBLA 1CWDL 1OPLA 2C0IA 1O4LA 4OHLA 1A1EA 1KA7A 2CR4A 2IZVA 1QCFA 3VRRA 4DGPA 1NZVA 4XZ1A 5CDWA 3UYOA 3BUXB 4OHHA 2CRHA 1A09A 4GL9E 1MW4A 1Y57A 3KFJA 1XA6A 4H34A 1K9AA 1OPKA 1O4DA 2LNWA 3CBLA 1X6CA 2HMHA 1BFIA 1GHUA 4FL3A 4EY0A 4K44A 1LUMA 2CI9A 1A81A 5GJIA 1O41A 3HHMB 3S9KA 3BUWB 3GXWA 3TL0A 2IUIA 1KA6A 2K7AB 1YVLA 3S8OA 1PICA 2DLZA 2DVJA 3VS3A 1A1BA 1O45A 4GWFA 4H1OA 1O43A 4P9ZA 1R1SA 3HIZB 1FBZA 4F59A 3OP0A 3ZNIA 2ECDA 2EO3A 4DGXA 2SHPA 1OO3A 2GE9A 2SRCA 5IBMA 1UURA 2EO6A 2CIAA 1F1WA 1TCEA 1O4OA 1BMBA 2RVFA 1RPYA 2EYVA 1JU5A 1BM2A 2ETZA 2EKXA 1IS0A 4D8KA 1X0NA 2Y3AB 2OZOA 2EU0A 2B3OA 2HDXA 4A4CA 3C7IA 4U1PA 2AUGA 1Y1UA 3US4A 4X6SA 2HDVA 3VS1A 1A1AA 1AYDA 4ROJA 4FL2A 4WWQA 5DC4A 2Y1MA 3N7YA 5GJHA 2RMXA 3VRNA 3HCKA 2K79B 2EOBA 1JYRA 2FCIA 3MAZA 4F5BA 1O4EA 2JYQA 3CWGA 4TZIA 5I6VA 1A07A 2LQNA 4K2RA 3PQZA 1Z3KA 3MXCA 1HCSB 2QMSA 3GQIB 5KAZA 4QSYA 1FYRA 5EHPA 3PLFB 4JEGA 5EG3B 1O4BA 1BLKA 1CWEA 1R1PA 4P9VA 2L4KA 1AYCA 3IN7A 3TKZA 4E93A 2VIFA 1RJAA 1D4TA 3BUMB 1D4WA 2C9WA 4L1BB 2Y1NA 3VRYA 4E68A 1UUSA 1D1ZA 1LUIA 1NZLA 1I3ZA 1M27A 4XZ0A 2DM0A 3EACA 1AD5A 3VS0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PTK A;  3CD3 A;  4NWG A;  5EHR A;  4GPL B;  2CI8 A;  2ABL A;  1MIL A;  3BUN B;  2MK2 A;  4EIH A;  3PJP A;  4K45 A;  3VS5 A;  5J3X A;  1O4F A;  5HKW A;  1JWO A;  2MRJ A;  1CJ1 A;  3MXY A;  1M61 A;  5HKY A;  3QWX X;  1KC2 A;  2PLE A;  4U17 A;  4A4B A;  1X27 A;  1CSZ A;  4NWF A;  1A08 A;  1O47 A;  3VRP A;  3IMD A;  1BLJ A;  4OHE A;  1BHH B;  4JE4 A;  1O4I A;  3BKB A;  1O44 A;  1CSY A;  1A1C A;  3WA4 A;  2HCK A;  3VRZ A;  3PSK A;  3S8N A;  2YU7 A;  1ZFP E;  1JYQ A;  1O4P A;  3GXX A;  5AXI A;  1O4G A;  1OO4 A;  2LNX A;  2HUW A;  2FO0 A;  3PSJ A;  1O4Q A;  2RSY A;  3N84 A;  3VS7 A;  3IN8 A;  3T04 A;  2YSX A;  1SHD A;  2BBU A;  2IUG A;  1LUK A;  3VS6 A;  1WQU A;  3EAZ A;  2LCT A;  1G83 A;  2GSB A;  2H46 E;  2PLD A;  1P13 A;  2L6K A;  2DLY A;  2MC1 A;  1NRV A;  4FBN A;  1AOU F;  1O48 A;  1YVH A;  3NHN A;  4JGH A;  1KSW A;  1QG1 E;  1O4H A;  5DC0 B;  4LUD A;  3VRO A;  3PFV A;  3CXL A;  5IBS A;  1F2F A;  1RQQ C;  4F5A A;  1BHH A;  1LCK A;  2EL8 A;  1SPS A;  1FBV A;  1BG1 A;  1LKK A;  2H5K A;  4OHD A;  1B47 A;  1H9O A;  1TZE E;  2XP1 A;  1IJR A;  1SPR A;  3QWY A;  3VRQ A;  3M7F A;  3K2M A;  1FU6 A;  1O49 A;  5DF6 A;  5HKZ A;  1LUN A;  1O4C A;  2C0O A;  1O4K A;  3OB1 B;  2CS0 A;  3VS2 A;  2DX0 A;  2IUH A;  4OHI A;  1AOT F;  2AOA A;  3OB2 B;  5EEQ A;  2PNA A;  1BF5 A;  3UF4 A;  1BHF A;  2KK6 A;  2ROR A;  2PNB A;  2C0T A;  1JYU A;  1O4J A;  2MQI A;  5AUL A;  3N8M A;  4LUE A;  1HCT B;  1O4N A;  2LQW A;  1FU5 A;  1AB2 A;  3PS5 A;  3OVE A;  2KNO A;  1BKM A;  1GRI A;  1O4R A;  2H8H A;  1QAD A;  5BO4 A;  1LCJ A;  1O42 A;  1R1Q A;  4K11 A;  3IMJ A;  1BKL A;  1FMK A;  3BUO B;  1O46 A;  1BFJ A;  2DCR A;  1O4A A;  5DC9 A;  1FHS A;  3VS4 A;  2AOB A;  4M4Z A;  3OV1 A;  1SKJ A;  1O4M A;  2L3T A;  1AYA A;  1SHB A;  5D0J A;  5EEL A;  2EYY A;  2OQ1 A;  2MRK A;  2EYZ A;  3VGO A;  1AYB A;  1SHA A;  3S8L A;  1LKL A;  2CBL A;  1CWD L;  1OPL A;  2C0I A;  1O4L A;  4OHL A;  1A1E A;  1KA7 A;  2CR4 A;  2IZV A;  1QCF A;  3VRR A;  4DGP A;  1NZV A;  4XZ1 A;  5CDW A;  3UYO A;  3BUX B;  4OHH A;  2CRH A;  1A09 A;  4GL9 E;  1MW4 A;  1Y57 A;  3KFJ A;  1XA6 A;  4H34 A;  1K9A A;  1OPK A;  1O4D A;  2LNW A;  3CBL A;  1X6C A;  2HMH A;  1BFI A;  1GHU A;  4FL3 A;  4EY0 A;  4K44 A;  1LUM A;  2CI9 A;  1A81 A;  5GJI A;  1O41 A;  3HHM B;  3S9K A;  3BUW B;  3GXW A;  3TL0 A;  2IUI A;  1KA6 A;  2K7A B;  1YVL A;  3S8O A;  1PIC A;  2DLZ A;  2DVJ A;  3VS3 A;  1A1B A;  1O45 A;  4GWF A;  4H1O A;  1O43 A;  4P9Z A;  1R1S A;  3HIZ B;  1FBZ A;  4F59 A;  3OP0 A;  3ZNI A;  2ECD A;  2EO3 A;  4DGX A;  2SHP A;  1OO3 A;  2GE9 A;  2SRC A;  5IBM A;  1UUR A;  2EO6 A;  2CIA A;  1F1W A;  1TCE A;  1O4O A;  1BMB A;  2RVF A;  1RPY A;  2EYV A;  1JU5 A;  1BM2 A;  2ETZ A;  2EKX A;  1IS0 A;  4D8K A;  1X0N A;  2Y3A B;  2OZO A;  2EU0 A;  2B3O A;  2HDX A;  4A4C A;  3C7I A;  4U1P A;  2AUG A;  1Y1U A;  3US4 A;  4X6S A;  2HDV A;  3VS1 A;  1A1A A;  1AYD A;  4ROJ A;  4FL2 A;  4WWQ A;  5DC4 A;  2Y1M A;  3N7Y A;  5GJH A;  2RMX A;  3VRN A;  3HCK A;  2K79 B;  2EOB A;  1JYR A;  2FCI A;  3MAZ A;  4F5B A;  1O4E A;  2JYQ A;  3CWG A;  4TZI A;  5I6V A;  1A07 A;  2LQN A;  4K2R A;  3PQZ A;  1Z3K A;  3MXC A;  1HCS B;  2QMS A;  3GQI B;  5KAZ A;  4QSY A;  1FYR A;  5EHP A;  3PLF B;  4JEG A;  5EG3 B;  1O4B A;  1BLK A;  1CWE A;  1R1P A;  4P9V A;  2L4K A;  1AYC A;  3IN7 A;  3TKZ A;  4E93 A;  2VIF A;  1RJA A;  1D4T A;  3BUM B;  1D4W A;  2C9W A;  4L1B B;  2Y1N A;  3VRY A;  4E68 A;  1UUS A;  1D1Z A;  1LUI A;  1NZL A;  1I3Z A;  1M27 A;  4XZ0 A;  2DM0 A;  3EAC A;  1AD5 A;  3VS0 A; 
#chains in the Genus database with same CATH topology
 2PTK A;  3CD3 A;  4NWG A;  5EHR A;  4GPL B;  2CI8 A;  2ABL A;  1MIL A;  3BUN B;  2MK2 A;  4EIH A;  3PJP A;  4K45 A;  3VS5 A;  5J3X A;  1O4F A;  5HKW A;  1JWO A;  2MRJ A;  1CJ1 A;  3MXY A;  1M61 A;  5HKY A;  3QWX X;  1KC2 A;  2PLE A;  4U17 A;  4A4B A;  1X27 A;  1CSZ A;  4NWF A;  1A08 A;  1O47 A;  3VRP A;  3IMD A;  1BLJ A;  4OHE A;  1BHH B;  4JE4 A;  1O4I A;  3BKB A;  1O44 A;  1CSY A;  1A1C A;  3WA4 A;  2HCK A;  3VRZ A;  3PSK A;  3S8N A;  2YU7 A;  3LYV A;  1ZFP E;  1JYQ A;  1O4P A;  3GXX A;  5AXI A;  1O4G A;  1OO4 A;  2LNX A;  2HUW A;  2FO0 A;  3PSJ A;  1O4Q A;  2RSY A;  3N84 A;  3VS7 A;  3IN8 A;  3T04 A;  2YSX A;  1SHD A;  2BBU A;  2IUG A;  1LUK A;  3VS6 A;  1WQU A;  3EAZ A;  2LCT A;  1G83 A;  2GSB A;  2H46 E;  2PLD A;  1P13 A;  2L6K A;  2DLY A;  2MC1 A;  1NRV A;  4FBN A;  1AOU F;  1O48 A;  1YVH A;  3NHN A;  4JGH A;  1KSW A;  1QG1 E;  1O4H A;  5DC0 B;  4LUD A;  3VRO A;  3PFV A;  3CXL A;  5IBS A;  1F2F A;  1RQQ C;  4F5A A;  1BHH A;  1LCK A;  2EL8 A;  1SPS A;  1FBV A;  1BG1 A;  1LKK A;  2H5K A;  4OHD A;  1B47 A;  1H9O A;  1TZE E;  2XP1 A;  1IJR A;  1SPR A;  3QWY A;  3VRQ A;  3M7F A;  3K2M A;  1FU6 A;  1O49 A;  5DF6 A;  5HKZ A;  1LUN A;  1O4C A;  2C0O A;  1O4K A;  3OB1 B;  2CS0 A;  3VS2 A;  2DX0 A;  2IUH A;  4OHI A;  1AOT F;  2AOA A;  3OB2 B;  5EEQ A;  2PNA A;  1BF5 A;  3UF4 A;  1BHF A;  2KK6 A;  2ROR A;  2PNB A;  2C0T A;  1JYU A;  1O4J A;  2MQI A;  5AUL A;  3N8M A;  4LUE A;  1HCT B;  1O4N A;  2LQW A;  1FU5 A;  1AB2 A;  3PS5 A;  3OVE A;  2KNO A;  1BKM A;  1GRI A;  1O4R A;  2H8H A;  1QAD A;  5BO4 A;  1LCJ A;  1O42 A;  3K2T A;  1R1Q A;  4K11 A;  3IMJ A;  1BKL A;  1FMK A;  3BUO B;  1O46 A;  1BFJ A;  2DCR A;  1O4A A;  5DC9 A;  1FHS A;  3VS4 A;  2AOB A;  4M4Z A;  3OV1 A;  1SKJ A;  1O4M A;  2L3T A;  1AYA A;  1SHB A;  5D0J A;  5EEL A;  2EYY A;  2OQ1 A;  2MRK A;  2EYZ A;  3VGO A;  1AYB A;  1SHA A;  3S8L A;  1LKL A;  2CBL A;  1CWD L;  1OPL A;  2C0I A;  1O4L A;  4OHL A;  1A1E A;  1KA7 A;  2CR4 A;  2IZV A;  1QCF A;  3VRR A;  4DGP A;  1NZV A;  4XZ1 A;  5CDW A;  3UYO A;  3BUX B;  4OHH A;  2CRH A;  1A09 A;  4GL9 E;  2LRA A;  1MW4 A;  1Y57 A;  3KFJ A;  1XA6 A;  4H34 A;  1K9A A;  1OPK A;  1O4D A;  2LNW A;  3CBL A;  1X6C A;  2HMH A;  1BFI A;  1GHU A;  4FL3 A;  4EY0 A;  4K44 A;  1LUM A;  2CI9 A;  1A81 A;  5GJI A;  1O41 A;  3HHM B;  3S9K A;  3BUW B;  3GXW A;  3TL0 A;  2IUI A;  1KA6 A;  2K7A B;  1YVL A;  3S8O A;  1PIC A;  2DLZ A;  2DVJ A;  3VS3 A;  1A1B A;  1O45 A;  4GWF A;  4H1O A;  1O43 A;  4P9Z A;  1R1S A;  3HIZ B;  1FBZ A;  4F59 A;  3OP0 A;  3ZNI A;  2ECD A;  2EO3 A;  4DGX A;  2SHP A;  1OO3 A;  2GE9 A;  2SRC A;  5IBM A;  1UUR A;  2EO6 A;  2CIA A;  1F1W A;  1TCE A;  1O4O A;  1BMB A;  2RVF A;  1RPY A;  2EYV A;  1JU5 A;  1BM2 A;  2ETZ A;  2EKX A;  2KGY A;  1IS0 A;  4D8K A;  1X0N A;  2Y3A B;  2OZO A;  2EU0 A;  2B3O A;  2HDX A;  4A4C A;  3C7I A;  4U1P A;  2AUG A;  1Y1U A;  3US4 A;  4X6S A;  2HDV A;  3VS1 A;  1A1A A;  1AYD A;  4ROJ A;  4FL2 A;  4WWQ A;  5DC4 A;  2Y1M A;  3N7Y A;  5GJH A;  2RMX A;  3VRN A;  3HCK A;  2K79 B;  2EOB A;  1JYR A;  2FCI A;  3MAZ A;  4F5B A;  1O4E A;  2JYQ A;  3CWG A;  4TZI A;  5I6V A;  1A07 A;  2LQN A;  4K2R A;  3PQZ A;  1Z3K A;  3MXC A;  1HCS B;  2QMS A;  3GQI B;  5KAZ A;  4QSY A;  1FYR A;  5EHP A;  3PLF B;  4JEG A;  5EG3 B;  1O4B A;  1BLK A;  1CWE A;  1R1P A;  4P9V A;  2L4K A;  1AYC A;  3IN7 A;  3TKZ A;  4E93 A;  2VIF A;  1RJA A;  1D4T A;  3BUM B;  1D4W A;  2C9W A;  4L1B B;  2Y1N A;  3VRY A;  4E68 A;  1UUS A;  1D1Z A;  1LUI A;  1NZL A;  1I3Z A;  1M27 A;  4XZ0 A;  2DM0 A;  3EAC A;  1AD5 A;  3VS0 A; 
#chains in the Genus database with same CATH homology
 2PTK A;  3CD3 A;  4NWG A;  5EHR A;  4GPL B;  2CI8 A;  2ABL A;  1MIL A;  3BUN B;  2MK2 A;  4EIH A;  3PJP A;  4K45 A;  3VS5 A;  5J3X A;  1O4F A;  5HKW A;  1JWO A;  2MRJ A;  1CJ1 A;  3MXY A;  1M61 A;  5HKY A;  3QWX X;  1KC2 A;  2PLE A;  4U17 A;  4A4B A;  1X27 A;  1CSZ A;  4NWF A;  1A08 A;  1O47 A;  3VRP A;  3IMD A;  1BLJ A;  4OHE A;  1BHH B;  4JE4 A;  1O4I A;  3BKB A;  1O44 A;  1CSY A;  1A1C A;  3WA4 A;  2HCK A;  3VRZ A;  3PSK A;  3S8N A;  2YU7 A;  1ZFP E;  1JYQ A;  1O4P A;  3GXX A;  5AXI A;  1O4G A;  1OO4 A;  2LNX A;  2HUW A;  2FO0 A;  3PSJ A;  1O4Q A;  2RSY A;  3N84 A;  3VS7 A;  3IN8 A;  3T04 A;  2YSX A;  1SHD A;  2BBU A;  2IUG A;  1LUK A;  3VS6 A;  1WQU A;  3EAZ A;  2LCT A;  1G83 A;  2GSB A;  2H46 E;  2PLD A;  1P13 A;  2L6K A;  2DLY A;  2MC1 A;  1NRV A;  4FBN A;  1AOU F;  1O48 A;  1YVH A;  3NHN A;  4JGH A;  1KSW A;  1QG1 E;  1O4H A;  5DC0 B;  4LUD A;  3VRO A;  3PFV A;  3CXL A;  5IBS A;  1F2F A;  1RQQ C;  4F5A A;  1BHH A;  1LCK A;  2EL8 A;  1SPS A;  1FBV A;  1BG1 A;  1LKK A;  2H5K A;  4OHD A;  1B47 A;  1H9O A;  1TZE E;  2XP1 A;  1IJR A;  1SPR A;  3QWY A;  3VRQ A;  3M7F A;  3K2M A;  1FU6 A;  1O49 A;  5DF6 A;  5HKZ A;  1LUN A;  1O4C A;  2C0O A;  1O4K A;  3OB1 B;  2CS0 A;  3VS2 A;  2DX0 A;  2IUH A;  4OHI A;  1AOT F;  2AOA A;  3OB2 B;  5EEQ A;  2PNA A;  1BF5 A;  3UF4 A;  1BHF A;  2KK6 A;  2ROR A;  2PNB A;  2C0T A;  1JYU A;  1O4J A;  2MQI A;  5AUL A;  3N8M A;  4LUE A;  1HCT B;  1O4N A;  2LQW A;  1FU5 A;  1AB2 A;  3PS5 A;  3OVE A;  2KNO A;  1BKM A;  1GRI A;  1O4R A;  2H8H A;  1QAD A;  5BO4 A;  1LCJ A;  1O42 A;  1R1Q A;  4K11 A;  3IMJ A;  1BKL A;  1FMK A;  3BUO B;  1O46 A;  1BFJ A;  2DCR A;  1O4A A;  5DC9 A;  1FHS A;  3VS4 A;  2AOB A;  4M4Z A;  3OV1 A;  1SKJ A;  1O4M A;  2L3T A;  1AYA A;  1SHB A;  5D0J A;  5EEL A;  2EYY A;  2OQ1 A;  2MRK A;  2EYZ A;  3VGO A;  1AYB A;  1SHA A;  3S8L A;  1LKL A;  2CBL A;  1CWD L;  1OPL A;  2C0I A;  1O4L A;  4OHL A;  1A1E A;  1KA7 A;  2CR4 A;  2IZV A;  1QCF A;  3VRR A;  4DGP A;  1NZV A;  4XZ1 A;  5CDW A;  3UYO A;  3BUX B;  4OHH A;  2CRH A;  1A09 A;  4GL9 E;  1MW4 A;  1Y57 A;  3KFJ A;  1XA6 A;  4H34 A;  1K9A A;  1OPK A;  1O4D A;  2LNW A;  3CBL A;  1X6C A;  2HMH A;  1BFI A;  1GHU A;  4FL3 A;  4EY0 A;  4K44 A;  1LUM A;  2CI9 A;  1A81 A;  5GJI A;  1O41 A;  3HHM B;  3S9K A;  3BUW B;  3GXW A;  3TL0 A;  2IUI A;  1KA6 A;  2K7A B;  1YVL A;  3S8O A;  1PIC A;  2DLZ A;  2DVJ A;  3VS3 A;  1A1B A;  1O45 A;  4GWF A;  4H1O A;  1O43 A;  4P9Z A;  1R1S A;  3HIZ B;  1FBZ A;  4F59 A;  3OP0 A;  3ZNI A;  2ECD A;  2EO3 A;  4DGX A;  2SHP A;  1OO3 A;  2GE9 A;  2SRC A;  5IBM A;  1UUR A;  2EO6 A;  2CIA A;  1F1W A;  1TCE A;  1O4O A;  1BMB A;  2RVF A;  1RPY A;  2EYV A;  1JU5 A;  1BM2 A;  2ETZ A;  2EKX A;  1IS0 A;  4D8K A;  1X0N A;  2Y3A B;  2OZO A;  2EU0 A;  2B3O A;  2HDX A;  4A4C A;  3C7I A;  4U1P A;  2AUG A;  1Y1U A;  3US4 A;  4X6S A;  2HDV A;  3VS1 A;  1A1A A;  1AYD A;  4ROJ A;  4FL2 A;  4WWQ A;  5DC4 A;  2Y1M A;  3N7Y A;  5GJH A;  2RMX A;  3VRN A;  3HCK A;  2K79 B;  2EOB A;  1JYR A;  2FCI A;  3MAZ A;  4F5B A;  1O4E A;  2JYQ A;  3CWG A;  4TZI A;  5I6V A;  1A07 A;  2LQN A;  4K2R A;  3PQZ A;  1Z3K A;  3MXC A;  1HCS B;  2QMS A;  3GQI B;  5KAZ A;  4QSY A;  1FYR A;  5EHP A;  3PLF B;  4JEG A;  5EG3 B;  1O4B A;  1BLK A;  1CWE A;  1R1P A;  4P9V A;  2L4K A;  1AYC A;  3IN7 A;  3TKZ A;  4E93 A;  2VIF A;  1RJA A;  1D4T A;  3BUM B;  1D4W A;  2C9W A;  4L1B B;  2Y1N A;  3VRY A;  4E68 A;  1UUS A;  1D1Z A;  1LUI A;  1NZL A;  1I3Z A;  1M27 A;  4XZ0 A;  2DM0 A;  3EAC A;  1AD5 A;  3VS0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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