2LCTA

Solution structure of the vav1 sh2 domain complexed with a syk-derived doubly phosphorylated peptide
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
107
structure length
107
Chain Sequence
GHMQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Proto-oncogene vav
total genus 29
structure length 107
sequence length 107
ec nomenclature
pdb deposition date 2011-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 2lctA01
2ETZA 3IMJA 3EAZA 1O4NA 5DC9A 1GRIA 2CIAA 3UF4A 2SRCA 3UYOA 1KSWA 1O4JA 2AUGA 2LQWA 2EO3A 1BFIA 1YVLA 3NHNA 1HCSB 2C0TA 1NRVA 4K11A 1O4GA 2AOBA 3S8LA 1IS0A 1QG1E 1SHAA 5KAZA 2PLDA 1O41A 3US4A 3EACA 3TKZA 3M7FA 2XP1A 5HKYA 1FMKA 1TZEE 1BFJA 1JYRA 3GXXA 4U1PA 3GQIB 4H1OA 5AXIA 3PS5A 5GJIA 3VRZA 2L4KA 1P13A 1SPSA 3HIZB 2C9WA 5AULA 2BBUA 3BUNB 3OB1B 4JGHA 3S8NA 2EL8A 4P9VA 3ZNIA 1SHBA 1JYQA 5IBSA 1B47A 3PSJA 1H9OA 1AYDA 3MAZA 2MRJA 4ROJA 4OHLA 3PJPA 3VRYA 3BUOB 3C7IA 4QSYA 4DGXA 5IBMA 1AOTF 4E68A 1BHHB 2LNWA 1BG1A 1SKJA 1O42A 2RVFA 3VS4A 3VROA 1R1SA 1O4RA 2C0OA 2GSBA 1WQUA 2RSYA 1IJRA 3VRPA 1TCEA 1O4AA 2KK6A 1BLJA 1O4MA 2PLEA 3PSKA 2HDXA 1O4KA 1FBZA 1BMBA 1XA6A 2CI9A 1Z3KA 3OV1A 3T04A 1O4FA 2RORA 1O44A 5EELA 2EOBA 1I3ZA 1RPYA 3QWXX 1A09A 1O45A 1BKMA 2MRKA 1CSYA 4WWQA 3BUWB 4XZ1A 1O4DA 4OHEA 3OVEA 2IUHA 4OHHA 2ABLA 2C0IA 1O47A 2IUIA 5HKWA 5J3XA 4GL9E 2EYVA 5GJHA 1LUMA 1OPKA 3VS7A 2L3TA 2VIFA 3CD3A 1O49A 5D0JA 1UUSA 2PNAA 4LUEA 1O46A 2FCIA 3BUMB 1Y1UA 2ECDA 5EEQA 1LKLA 5HKZA 2PTKA 5BO4A 4F5BA 1FU5A 1FBVA 1A1EA 3KFJA 3CWGA 3PQZA 1JWOA 1O4QA 1K9AA 1BHHA 4NWGA 4D8KA 1OPLA 1M27A 3OP0A 2SHPA 1LKKA 3HHMB 1QCFA 1PICA 1X0NA 4H34A 1JU5A 1X6CA 2H5KA 2H8HA 3VRNA 1D4TA 5I6VA 1KA6A 1QADA 2CI8A 2CR4A 4EIHA 1F2FA 1O43A 1UURA 4TZIA 1O48A 5EHPA 2FO0A 1FYRA 2EU0A 2MQIA 1AYBA 4NWFA 1FHSA 1BM2A 4K44A 4XZ0A 2LNXA 1CWEA 3MXCA 1O4HA 3IN8A 2H46E 1LCJA 2MK2A 4OHDA 1RJAA 1JYUA 5EHRA 1A1BA 2HCKA 2RMXA 2DLYA 3CXLA 2Y1NA 1F1WA 2LCTA 1AOUF 1CJ1A 3N7YA 2IZVA 5EG3B 1O4IA 2HMHA 2DM0A 3MXYA 3PLFB 1AD5A 4F59A 1OO4A 2Y1MA 2PNBA 3IMDA 1ZFPE 3VRQA 2HUWA 3VS1A 1LUNA 1BF5A 4X6SA 1SHDA 1A08A 1A81A 1O4PA 3CBLA 3IN7A 1A1AA 1LUIA 3QWYA 2DCRA 4FL3A 2EYYA 1GHUA 2EO6A 3TL0A 3VS5A 1G83A 2JYQA 3HCKA 1O4OA 4U17A 3S9KA 1BKLA 3GXWA 3S8OA 1M61A 2IUGA 5CDWA 2DVJA 2EYZA 1LUKA 3WA4A 3VGOA 2OQ1A 2K79B 1O4CA 1D1ZA 1O4EA 2YSXA 3VRRA 2DLZA 2K7AB 2MC1A 3K2MA 2Y3AB 2L6KA 3OB2B 1A1CA 1CSZA 2AOAA 3VS0A 1BHFA 4JE4A 1YVHA 1OO3A 2DX0A 1O4LA 2LQNA 1AYCA 1CWDL 1MW4A 4K45A 4DGPA 1AB2A 3PFVA 2B3OA 1X27A 4OHIA 2KNOA 1SPRA 4GWFA 3N8MA 1RQQC 2CS0A 1A07A 1KC2A 2YU7A 2QMSA 1KA7A 3VS6A 2CRHA 4JEGA 1AYAA 4M4ZA 1R1PA 1R1QA 5DC0B 5DF6A 1O4BA 4L1BB 1LCKA 4FL2A 3N84A 5DC4A 1MILA 2GE9A 3VS3A 4GPLB 2EKXA 1Y57A 1FU6A 4LUDA 4P9ZA 2HDVA 4FBNA 4E93A 1BLKA 2OZOA 1NZVA 1D4WA 4A4CA 1HCTB 3BUXB 4K2RA 3BKBA 4A4BA 4EY0A 3VS2A 1NZLA 4F5AA 2CBLA
chains in the Genus database with same CATH superfamily
2ETZA 3IMJA 3EAZA 1O4NA 5DC9A 1GRIA 2CIAA 3UF4A 2SRCA 3UYOA 1KSWA 1O4JA 2AUGA 2LQWA 2EO3A 1BFIA 1YVLA 3NHNA 1HCSB 2C0TA 1NRVA 4K11A 1O4GA 3LYVA 2AOBA 3S8LA 1IS0A 1QG1E 1SHAA 5KAZA 2PLDA 1O41A 3US4A 3EACA 3TKZA 3M7FA 2XP1A 5HKYA 1FMKA 1TZEE 1BFJA 1JYRA 3GXXA 4U1PA 3GQIB 4H1OA 5AXIA 3PS5A 5GJIA 3VRZA 2L4KA 1P13A 1SPSA 3HIZB 2C9WA 5AULA 2BBUA 3BUNB 3OB1B 4JGHA 3S8NA 2EL8A 4P9VA 3ZNIA 1SHBA 1JYQA 5IBSA 1B47A 2LRAA 3PSJA 1H9OA 1AYDA 3MAZA 2MRJA 4ROJA 4OHLA 3PJPA 3VRYA 3BUOB 3C7IA 4QSYA 4DGXA 5IBMA 1AOTF 4E68A 1BHHB 2LNWA 1BG1A 1SKJA 1O42A 2RVFA 3VS4A 3VROA 1R1SA 1O4RA 2C0OA 2GSBA 1WQUA 2RSYA 1IJRA 3VRPA 1TCEA 1O4AA 2KK6A 1BLJA 1O4MA 2PLEA 3PSKA 2HDXA 1O4KA 1FBZA 1BMBA 1XA6A 2CI9A 1Z3KA 3OV1A 3T04A 1O4FA 2RORA 1O44A 5EELA 2EOBA 1I3ZA 1RPYA 3QWXX 1A09A 1O45A 1BKMA 2MRKA 1CSYA 4WWQA 3BUWB 4XZ1A 1O4DA 4OHEA 3OVEA 2IUHA 4OHHA 2ABLA 2C0IA 1O47A 2IUIA 5HKWA 5J3XA 4GL9E 2EYVA 5GJHA 1LUMA 1OPKA 3VS7A 2L3TA 2VIFA 3CD3A 1O49A 5D0JA 1UUSA 2PNAA 4LUEA 1O46A 2FCIA 3BUMB 1Y1UA 2ECDA 5EEQA 1LKLA 5HKZA 2PTKA 5BO4A 4F5BA 1FU5A 1FBVA 1A1EA 3KFJA 3CWGA 3PQZA 1JWOA 1O4QA 1K9AA 1BHHA 4NWGA 4D8KA 1OPLA 1M27A 3OP0A 2SHPA 1LKKA 3HHMB 1QCFA 1PICA 1X0NA 2KGYA 4H34A 1JU5A 1X6CA 2H5KA 2H8HA 3VRNA 1D4TA 5I6VA 1KA6A 1QADA 2CI8A 2CR4A 4EIHA 1F2FA 1O43A 1UURA 4TZIA 1O48A 5EHPA 2FO0A 1FYRA 2EU0A 2MQIA 1AYBA 4NWFA 1FHSA 1BM2A 4K44A 4XZ0A 2LNXA 1CWEA 3MXCA 1O4HA 3IN8A 2H46E 1LCJA 2MK2A 4OHDA 1RJAA 1JYUA 5EHRA 1A1BA 2HCKA 2RMXA 2DLYA 3CXLA 2Y1NA 1F1WA 2LCTA 1AOUF 1CJ1A 3N7YA 2IZVA 5EG3B 1O4IA 2HMHA 2DM0A 3MXYA 3PLFB 1AD5A 4F59A 1OO4A 2Y1MA 2PNBA 3IMDA 1ZFPE 3VRQA 2HUWA 3VS1A 1LUNA 1BF5A 4X6SA 1SHDA 1A08A 1A81A 1O4PA 3CBLA 3IN7A 1A1AA 1LUIA 3QWYA 2DCRA 4FL3A 2EYYA 1GHUA 2EO6A 3TL0A 3VS5A 1G83A 2JYQA 3HCKA 1O4OA 4U17A 3S9KA 1BKLA 3GXWA 3S8OA 1M61A 2IUGA 5CDWA 2DVJA 2EYZA 1LUKA 3K2TA 3WA4A 3VGOA 2OQ1A 2K79B 1O4CA 1D1ZA 1O4EA 2YSXA 3VRRA 2DLZA 2K7AB 2MC1A 3K2MA 2Y3AB 2L6KA 3OB2B 1A1CA 1CSZA 2AOAA 3VS0A 1BHFA 4JE4A 1YVHA 1OO3A 2DX0A 1O4LA 2LQNA 1AYCA 1CWDL 1MW4A 4K45A 4DGPA 1AB2A 3PFVA 2B3OA 1X27A 4OHIA 2KNOA 1SPRA 4GWFA 3N8MA 1RQQC 2CS0A 1A07A 1KC2A 2YU7A 2QMSA 1KA7A 3VS6A 2CRHA 4JEGA 1AYAA 4M4ZA 1R1PA 1R1QA 5DC0B 5DF6A 1O4BA 4L1BB 1LCKA 4FL2A 3N84A 5DC4A 1MILA 2GE9A 3VS3A 4GPLB 2EKXA 1Y57A 1FU6A 4LUDA 4P9ZA 2HDVA 4FBNA 4E93A 1BLKA 2OZOA 1NZVA 1D4WA 4A4CA 1HCTB 3BUXB 4K2RA 3BKBA 4A4BA 4EY0A 3VS2A 1NZLA 4F5AA 2CBLA
chains in the Genus database with same CATH topology
2ETZA 3IMJA 3EAZA 1O4NA 5DC9A 1GRIA 2CIAA 3UF4A 2SRCA 3UYOA 1KSWA 1O4JA 2AUGA 2LQWA 2EO3A 1BFIA 1YVLA 3NHNA 1HCSB 2C0TA 1NRVA 4K11A 1O4GA 2AOBA 3S8LA 1IS0A 1QG1E 1SHAA 5KAZA 2PLDA 1O41A 3US4A 3EACA 3TKZA 3M7FA 2XP1A 5HKYA 1FMKA 1TZEE 1BFJA 1JYRA 3GXXA 4U1PA 3GQIB 4H1OA 5AXIA 3PS5A 5GJIA 3VRZA 2L4KA 1P13A 1SPSA 3HIZB 2C9WA 5AULA 2BBUA 3BUNB 3OB1B 4JGHA 3S8NA 2EL8A 4P9VA 3ZNIA 1SHBA 1JYQA 5IBSA 1B47A 3PSJA 1H9OA 1AYDA 3MAZA 2MRJA 4ROJA 4OHLA 3PJPA 3VRYA 3BUOB 3C7IA 4QSYA 4DGXA 5IBMA 1AOTF 4E68A 1BHHB 2LNWA 1BG1A 1SKJA 1O42A 2RVFA 3VS4A 3VROA 1R1SA 1O4RA 2C0OA 2GSBA 1WQUA 2RSYA 1IJRA 3VRPA 1TCEA 1O4AA 2KK6A 1BLJA 1O4MA 2PLEA 3PSKA 2HDXA 1O4KA 1FBZA 1BMBA 1XA6A 2CI9A 1Z3KA 3OV1A 3T04A 1O4FA 2RORA 1O44A 5EELA 2EOBA 1I3ZA 1RPYA 3QWXX 1A09A 1O45A 1BKMA 2MRKA 1CSYA 4WWQA 3BUWB 4XZ1A 1O4DA 4OHEA 3OVEA 2IUHA 4OHHA 2ABLA 2C0IA 1O47A 2IUIA 5HKWA 5J3XA 4GL9E 2EYVA 5GJHA 1LUMA 1OPKA 3VS7A 2L3TA 2VIFA 3CD3A 1O49A 5D0JA 1UUSA 2PNAA 4LUEA 1O46A 2FCIA 3BUMB 1Y1UA 2ECDA 5EEQA 1LKLA 5HKZA 2PTKA 5BO4A 4F5BA 1FU5A 1FBVA 1A1EA 3KFJA 3CWGA 3PQZA 1JWOA 1O4QA 1K9AA 1BHHA 4NWGA 4D8KA 1OPLA 1M27A 3OP0A 2SHPA 1LKKA 3HHMB 1QCFA 1PICA 1X0NA 4H34A 1JU5A 1X6CA 2H5KA 2H8HA 3VRNA 1D4TA 5I6VA 1KA6A 1QADA 2CI8A 2CR4A 4EIHA 1F2FA 1O43A 1UURA 4TZIA 1O48A 5EHPA 2FO0A 1FYRA 2EU0A 2MQIA 1AYBA 4NWFA 1FHSA 1BM2A 4K44A 4XZ0A 2LNXA 1CWEA 3MXCA 1O4HA 3IN8A 2H46E 1LCJA 2MK2A 4OHDA 1RJAA 1JYUA 5EHRA 1A1BA 2HCKA 2RMXA 2DLYA 3CXLA 2Y1NA 1F1WA 2LCTA 1AOUF 1CJ1A 3N7YA 2IZVA 5EG3B 1O4IA 2HMHA 2DM0A 3MXYA 3PLFB 1AD5A 4F59A 1OO4A 2Y1MA 2PNBA 3IMDA 1ZFPE 3VRQA 2HUWA 3VS1A 1LUNA 1BF5A 4X6SA 1SHDA 1A08A 1A81A 1O4PA 3CBLA 3IN7A 1A1AA 1LUIA 3QWYA 2DCRA 4FL3A 2EYYA 1GHUA 2EO6A 3TL0A 3VS5A 1G83A 2JYQA 3HCKA 1O4OA 4U17A 3S9KA 1BKLA 3GXWA 3S8OA 1M61A 2IUGA 5CDWA 2DVJA 2EYZA 1LUKA 3WA4A 3VGOA 2OQ1A 2K79B 1O4CA 1D1ZA 1O4EA 2YSXA 3VRRA 2DLZA 2K7AB 2MC1A 3K2MA 2Y3AB 2L6KA 3OB2B 1A1CA 1CSZA 2AOAA 3VS0A 1BHFA 4JE4A 1YVHA 1OO3A 2DX0A 1O4LA 2LQNA 1AYCA 1CWDL 1MW4A 4K45A 4DGPA 1AB2A 3PFVA 2B3OA 1X27A 4OHIA 2KNOA 1SPRA 4GWFA 3N8MA 1RQQC 2CS0A 1A07A 1KC2A 2YU7A 2QMSA 1KA7A 3VS6A 2CRHA 4JEGA 1AYAA 4M4ZA 1R1PA 1R1QA 5DC0B 5DF6A 1O4BA 4L1BB 1LCKA 4FL2A 3N84A 5DC4A 1MILA 2GE9A 3VS3A 4GPLB 2EKXA 1Y57A 1FU6A 4LUDA 4P9ZA 2HDVA 4FBNA 4E93A 1BLKA 2OZOA 1NZVA 1D4WA 4A4CA 1HCTB 3BUXB 4K2RA 3BKBA 4A4BA 4EY0A 3VS2A 1NZLA 4F5AA 2CBLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ETZ A;  3IMJ A;  3EAZ A;  1O4N A;  5DC9 A;  1GRI A;  2CIA A;  3UF4 A;  2SRC A;  3UYO A;  1KSW A;  1O4J A;  2AUG A;  2LQW A;  2EO3 A;  1BFI A;  1YVL A;  3NHN A;  1HCS B;  2C0T A;  1NRV A;  4K11 A;  1O4G A;  2AOB A;  3S8L A;  1IS0 A;  1QG1 E;  1SHA A;  5KAZ A;  2PLD A;  1O41 A;  3US4 A;  3EAC A;  3TKZ A;  3M7F A;  2XP1 A;  5HKY A;  1FMK A;  1TZE E;  1BFJ A;  1JYR A;  3GXX A;  4U1P A;  3GQI B;  4H1O A;  5AXI A;  3PS5 A;  5GJI A;  3VRZ A;  2L4K A;  1P13 A;  1SPS A;  3HIZ B;  2C9W A;  5AUL A;  2BBU A;  3BUN B;  3OB1 B;  4JGH A;  3S8N A;  2EL8 A;  4P9V A;  3ZNI A;  1SHB A;  1JYQ A;  5IBS A;  1B47 A;  3PSJ A;  1H9O A;  1AYD A;  3MAZ A;  2MRJ A;  4ROJ A;  4OHL A;  3PJP A;  3VRY A;  3BUO B;  3C7I A;  4QSY A;  4DGX A;  5IBM A;  1AOT F;  4E68 A;  1BHH B;  2LNW A;  1BG1 A;  1SKJ A;  1O42 A;  2RVF A;  3VS4 A;  3VRO A;  1R1S A;  1O4R A;  2C0O A;  2GSB A;  1WQU A;  2RSY A;  1IJR A;  3VRP A;  1TCE A;  1O4A A;  2KK6 A;  1BLJ A;  1O4M A;  2PLE A;  3PSK A;  2HDX A;  1O4K A;  1FBZ A;  1BMB A;  1XA6 A;  2CI9 A;  1Z3K A;  3OV1 A;  3T04 A;  1O4F A;  2ROR A;  1O44 A;  5EEL A;  2EOB A;  1I3Z A;  1RPY A;  3QWX X;  1A09 A;  1O45 A;  1BKM A;  2MRK A;  1CSY A;  4WWQ A;  3BUW B;  4XZ1 A;  1O4D A;  4OHE A;  3OVE A;  2IUH A;  4OHH A;  2ABL A;  2C0I A;  1O47 A;  2IUI A;  5HKW A;  5J3X A;  4GL9 E;  2EYV A;  5GJH A;  1LUM A;  1OPK A;  3VS7 A;  2L3T A;  2VIF A;  3CD3 A;  1O49 A;  5D0J A;  1UUS A;  2PNA A;  4LUE A;  1O46 A;  2FCI A;  3BUM B;  1Y1U A;  2ECD A;  5EEQ A;  1LKL A;  5HKZ A;  2PTK A;  5BO4 A;  4F5B A;  1FU5 A;  1FBV A;  1A1E A;  3KFJ A;  3CWG A;  3PQZ A;  1JWO A;  1O4Q A;  1K9A A;  1BHH A;  4NWG A;  4D8K A;  1OPL A;  1M27 A;  3OP0 A;  2SHP A;  1LKK A;  3HHM B;  1QCF A;  1PIC A;  1X0N A;  4H34 A;  1JU5 A;  1X6C A;  2H5K A;  2H8H A;  3VRN A;  1D4T A;  5I6V A;  1KA6 A;  1QAD A;  2CI8 A;  2CR4 A;  4EIH A;  1F2F A;  1O43 A;  1UUR A;  4TZI A;  1O48 A;  5EHP A;  2FO0 A;  1FYR A;  2EU0 A;  2MQI A;  1AYB A;  4NWF A;  1FHS A;  1BM2 A;  4K44 A;  4XZ0 A;  2LNX A;  1CWE A;  3MXC A;  1O4H A;  3IN8 A;  2H46 E;  1LCJ A;  2MK2 A;  4OHD A;  1RJA A;  1JYU A;  5EHR A;  1A1B A;  2HCK A;  2RMX A;  2DLY A;  3CXL A;  2Y1N A;  1F1W A;  2LCT A;  1AOU F;  1CJ1 A;  3N7Y A;  2IZV A;  5EG3 B;  1O4I A;  2HMH A;  2DM0 A;  3MXY A;  3PLF B;  1AD5 A;  4F59 A;  1OO4 A;  2Y1M A;  2PNB A;  3IMD A;  1ZFP E;  3VRQ A;  2HUW A;  3VS1 A;  1LUN A;  1BF5 A;  4X6S A;  1SHD A;  1A08 A;  1A81 A;  1O4P A;  3CBL A;  3IN7 A;  1A1A A;  1LUI A;  3QWY A;  2DCR A;  4FL3 A;  2EYY A;  1GHU A;  2EO6 A;  3TL0 A;  3VS5 A;  1G83 A;  2JYQ A;  3HCK A;  1O4O A;  4U17 A;  3S9K A;  1BKL A;  3GXW A;  3S8O A;  1M61 A;  2IUG A;  5CDW A;  2DVJ A;  2EYZ A;  1LUK A;  3WA4 A;  3VGO A;  2OQ1 A;  2K79 B;  1O4C A;  1D1Z A;  1O4E A;  2YSX A;  3VRR A;  2DLZ A;  2K7A B;  2MC1 A;  3K2M A;  2Y3A B;  2L6K A;  3OB2 B;  1A1C A;  1CSZ A;  2AOA A;  3VS0 A;  1BHF A;  4JE4 A;  1YVH A;  1OO3 A;  2DX0 A;  1O4L A;  2LQN A;  1AYC A;  1CWD L;  1MW4 A;  4K45 A;  4DGP A;  1AB2 A;  3PFV A;  2B3O A;  1X27 A;  4OHI A;  2KNO A;  1SPR A;  4GWF A;  3N8M A;  1RQQ C;  2CS0 A;  1A07 A;  1KC2 A;  2YU7 A;  2QMS A;  1KA7 A;  3VS6 A;  2CRH A;  4JEG A;  1AYA A;  4M4Z A;  1R1P A;  1R1Q A;  5DC0 B;  5DF6 A;  1O4B A;  4L1B B;  1LCK A;  4FL2 A;  3N84 A;  5DC4 A;  1MIL A;  2GE9 A;  3VS3 A;  4GPL B;  2EKX A;  1Y57 A;  1FU6 A;  4LUD A;  4P9Z A;  2HDV A;  4FBN A;  4E93 A;  1BLK A;  2OZO A;  1NZV A;  1D4W A;  4A4C A;  1HCT B;  3BUX B;  4K2R A;  3BKB A;  4A4B A;  4EY0 A;  3VS2 A;  1NZL A;  4F5A A;  2CBL A; 
#chains in the Genus database with same CATH topology
 2ETZ A;  3IMJ A;  3EAZ A;  1O4N A;  5DC9 A;  1GRI A;  2CIA A;  3UF4 A;  2SRC A;  3UYO A;  1KSW A;  1O4J A;  2AUG A;  2LQW A;  2EO3 A;  1BFI A;  1YVL A;  3NHN A;  1HCS B;  2C0T A;  1NRV A;  4K11 A;  1O4G A;  3LYV A;  2AOB A;  3S8L A;  1IS0 A;  1QG1 E;  1SHA A;  5KAZ A;  2PLD A;  1O41 A;  3US4 A;  3EAC A;  3TKZ A;  3M7F A;  2XP1 A;  5HKY A;  1FMK A;  1TZE E;  1BFJ A;  1JYR A;  3GXX A;  4U1P A;  3GQI B;  4H1O A;  5AXI A;  3PS5 A;  5GJI A;  3VRZ A;  2L4K A;  1P13 A;  1SPS A;  3HIZ B;  2C9W A;  5AUL A;  2BBU A;  3BUN B;  3OB1 B;  4JGH A;  3S8N A;  2EL8 A;  4P9V A;  3ZNI A;  1SHB A;  1JYQ A;  5IBS A;  1B47 A;  2LRA A;  3PSJ A;  1H9O A;  1AYD A;  3MAZ A;  2MRJ A;  4ROJ A;  4OHL A;  3PJP A;  3VRY A;  3BUO B;  3C7I A;  4QSY A;  4DGX A;  5IBM A;  1AOT F;  4E68 A;  1BHH B;  2LNW A;  1BG1 A;  1SKJ A;  1O42 A;  2RVF A;  3VS4 A;  3VRO A;  1R1S A;  1O4R A;  2C0O A;  2GSB A;  1WQU A;  2RSY A;  1IJR A;  3VRP A;  1TCE A;  1O4A A;  2KK6 A;  1BLJ A;  1O4M A;  2PLE A;  3PSK A;  2HDX A;  1O4K A;  1FBZ A;  1BMB A;  1XA6 A;  2CI9 A;  1Z3K A;  3OV1 A;  3T04 A;  1O4F A;  2ROR A;  1O44 A;  5EEL A;  2EOB A;  1I3Z A;  1RPY A;  3QWX X;  1A09 A;  1O45 A;  1BKM A;  2MRK A;  1CSY A;  4WWQ A;  3BUW B;  4XZ1 A;  1O4D A;  4OHE A;  3OVE A;  2IUH A;  4OHH A;  2ABL A;  2C0I A;  1O47 A;  2IUI A;  5HKW A;  5J3X A;  4GL9 E;  2EYV A;  5GJH A;  1LUM A;  1OPK A;  3VS7 A;  2L3T A;  2VIF A;  3CD3 A;  1O49 A;  5D0J A;  1UUS A;  2PNA A;  4LUE A;  1O46 A;  2FCI A;  3BUM B;  1Y1U A;  2ECD A;  5EEQ A;  1LKL A;  5HKZ A;  2PTK A;  5BO4 A;  4F5B A;  1FU5 A;  1FBV A;  1A1E A;  3KFJ A;  3CWG A;  3PQZ A;  1JWO A;  1O4Q A;  1K9A A;  1BHH A;  4NWG A;  4D8K A;  1OPL A;  1M27 A;  3OP0 A;  2SHP A;  1LKK A;  3HHM B;  1QCF A;  1PIC A;  1X0N A;  2KGY A;  4H34 A;  1JU5 A;  1X6C A;  2H5K A;  2H8H A;  3VRN A;  1D4T A;  5I6V A;  1KA6 A;  1QAD A;  2CI8 A;  2CR4 A;  4EIH A;  1F2F A;  1O43 A;  1UUR A;  4TZI A;  1O48 A;  5EHP A;  2FO0 A;  1FYR A;  2EU0 A;  2MQI A;  1AYB A;  4NWF A;  1FHS A;  1BM2 A;  4K44 A;  4XZ0 A;  2LNX A;  1CWE A;  3MXC A;  1O4H A;  3IN8 A;  2H46 E;  1LCJ A;  2MK2 A;  4OHD A;  1RJA A;  1JYU A;  5EHR A;  1A1B A;  2HCK A;  2RMX A;  2DLY A;  3CXL A;  2Y1N A;  1F1W A;  2LCT A;  1AOU F;  1CJ1 A;  3N7Y A;  2IZV A;  5EG3 B;  1O4I A;  2HMH A;  2DM0 A;  3MXY A;  3PLF B;  1AD5 A;  4F59 A;  1OO4 A;  2Y1M A;  2PNB A;  3IMD A;  1ZFP E;  3VRQ A;  2HUW A;  3VS1 A;  1LUN A;  1BF5 A;  4X6S A;  1SHD A;  1A08 A;  1A81 A;  1O4P A;  3CBL A;  3IN7 A;  1A1A A;  1LUI A;  3QWY A;  2DCR A;  4FL3 A;  2EYY A;  1GHU A;  2EO6 A;  3TL0 A;  3VS5 A;  1G83 A;  2JYQ A;  3HCK A;  1O4O A;  4U17 A;  3S9K A;  1BKL A;  3GXW A;  3S8O A;  1M61 A;  2IUG A;  5CDW A;  2DVJ A;  2EYZ A;  1LUK A;  3K2T A;  3WA4 A;  3VGO A;  2OQ1 A;  2K79 B;  1O4C A;  1D1Z A;  1O4E A;  2YSX A;  3VRR A;  2DLZ A;  2K7A B;  2MC1 A;  3K2M A;  2Y3A B;  2L6K A;  3OB2 B;  1A1C A;  1CSZ A;  2AOA A;  3VS0 A;  1BHF A;  4JE4 A;  1YVH A;  1OO3 A;  2DX0 A;  1O4L A;  2LQN A;  1AYC A;  1CWD L;  1MW4 A;  4K45 A;  4DGP A;  1AB2 A;  3PFV A;  2B3O A;  1X27 A;  4OHI A;  2KNO A;  1SPR A;  4GWF A;  3N8M A;  1RQQ C;  2CS0 A;  1A07 A;  1KC2 A;  2YU7 A;  2QMS A;  1KA7 A;  3VS6 A;  2CRH A;  4JEG A;  1AYA A;  4M4Z A;  1R1P A;  1R1Q A;  5DC0 B;  5DF6 A;  1O4B A;  4L1B B;  1LCK A;  4FL2 A;  3N84 A;  5DC4 A;  1MIL A;  2GE9 A;  3VS3 A;  4GPL B;  2EKX A;  1Y57 A;  1FU6 A;  4LUD A;  4P9Z A;  2HDV A;  4FBN A;  4E93 A;  1BLK A;  2OZO A;  1NZV A;  1D4W A;  4A4C A;  1HCT B;  3BUX B;  4K2R A;  3BKB A;  4A4B A;  4EY0 A;  3VS2 A;  1NZL A;  4F5A A;  2CBL A; 
#chains in the Genus database with same CATH homology
 2ETZ A;  3IMJ A;  3EAZ A;  1O4N A;  5DC9 A;  1GRI A;  2CIA A;  3UF4 A;  2SRC A;  3UYO A;  1KSW A;  1O4J A;  2AUG A;  2LQW A;  2EO3 A;  1BFI A;  1YVL A;  3NHN A;  1HCS B;  2C0T A;  1NRV A;  4K11 A;  1O4G A;  2AOB A;  3S8L A;  1IS0 A;  1QG1 E;  1SHA A;  5KAZ A;  2PLD A;  1O41 A;  3US4 A;  3EAC A;  3TKZ A;  3M7F A;  2XP1 A;  5HKY A;  1FMK A;  1TZE E;  1BFJ A;  1JYR A;  3GXX A;  4U1P A;  3GQI B;  4H1O A;  5AXI A;  3PS5 A;  5GJI A;  3VRZ A;  2L4K A;  1P13 A;  1SPS A;  3HIZ B;  2C9W A;  5AUL A;  2BBU A;  3BUN B;  3OB1 B;  4JGH A;  3S8N A;  2EL8 A;  4P9V A;  3ZNI A;  1SHB A;  1JYQ A;  5IBS A;  1B47 A;  3PSJ A;  1H9O A;  1AYD A;  3MAZ A;  2MRJ A;  4ROJ A;  4OHL A;  3PJP A;  3VRY A;  3BUO B;  3C7I A;  4QSY A;  4DGX A;  5IBM A;  1AOT F;  4E68 A;  1BHH B;  2LNW A;  1BG1 A;  1SKJ A;  1O42 A;  2RVF A;  3VS4 A;  3VRO A;  1R1S A;  1O4R A;  2C0O A;  2GSB A;  1WQU A;  2RSY A;  1IJR A;  3VRP A;  1TCE A;  1O4A A;  2KK6 A;  1BLJ A;  1O4M A;  2PLE A;  3PSK A;  2HDX A;  1O4K A;  1FBZ A;  1BMB A;  1XA6 A;  2CI9 A;  1Z3K A;  3OV1 A;  3T04 A;  1O4F A;  2ROR A;  1O44 A;  5EEL A;  2EOB A;  1I3Z A;  1RPY A;  3QWX X;  1A09 A;  1O45 A;  1BKM A;  2MRK A;  1CSY A;  4WWQ A;  3BUW B;  4XZ1 A;  1O4D A;  4OHE A;  3OVE A;  2IUH A;  4OHH A;  2ABL A;  2C0I A;  1O47 A;  2IUI A;  5HKW A;  5J3X A;  4GL9 E;  2EYV A;  5GJH A;  1LUM A;  1OPK A;  3VS7 A;  2L3T A;  2VIF A;  3CD3 A;  1O49 A;  5D0J A;  1UUS A;  2PNA A;  4LUE A;  1O46 A;  2FCI A;  3BUM B;  1Y1U A;  2ECD A;  5EEQ A;  1LKL A;  5HKZ A;  2PTK A;  5BO4 A;  4F5B A;  1FU5 A;  1FBV A;  1A1E A;  3KFJ A;  3CWG A;  3PQZ A;  1JWO A;  1O4Q A;  1K9A A;  1BHH A;  4NWG A;  4D8K A;  1OPL A;  1M27 A;  3OP0 A;  2SHP A;  1LKK A;  3HHM B;  1QCF A;  1PIC A;  1X0N A;  4H34 A;  1JU5 A;  1X6C A;  2H5K A;  2H8H A;  3VRN A;  1D4T A;  5I6V A;  1KA6 A;  1QAD A;  2CI8 A;  2CR4 A;  4EIH A;  1F2F A;  1O43 A;  1UUR A;  4TZI A;  1O48 A;  5EHP A;  2FO0 A;  1FYR A;  2EU0 A;  2MQI A;  1AYB A;  4NWF A;  1FHS A;  1BM2 A;  4K44 A;  4XZ0 A;  2LNX A;  1CWE A;  3MXC A;  1O4H A;  3IN8 A;  2H46 E;  1LCJ A;  2MK2 A;  4OHD A;  1RJA A;  1JYU A;  5EHR A;  1A1B A;  2HCK A;  2RMX A;  2DLY A;  3CXL A;  2Y1N A;  1F1W A;  2LCT A;  1AOU F;  1CJ1 A;  3N7Y A;  2IZV A;  5EG3 B;  1O4I A;  2HMH A;  2DM0 A;  3MXY A;  3PLF B;  1AD5 A;  4F59 A;  1OO4 A;  2Y1M A;  2PNB A;  3IMD A;  1ZFP E;  3VRQ A;  2HUW A;  3VS1 A;  1LUN A;  1BF5 A;  4X6S A;  1SHD A;  1A08 A;  1A81 A;  1O4P A;  3CBL A;  3IN7 A;  1A1A A;  1LUI A;  3QWY A;  2DCR A;  4FL3 A;  2EYY A;  1GHU A;  2EO6 A;  3TL0 A;  3VS5 A;  1G83 A;  2JYQ A;  3HCK A;  1O4O A;  4U17 A;  3S9K A;  1BKL A;  3GXW A;  3S8O A;  1M61 A;  2IUG A;  5CDW A;  2DVJ A;  2EYZ A;  1LUK A;  3WA4 A;  3VGO A;  2OQ1 A;  2K79 B;  1O4C A;  1D1Z A;  1O4E A;  2YSX A;  3VRR A;  2DLZ A;  2K7A B;  2MC1 A;  3K2M A;  2Y3A B;  2L6K A;  3OB2 B;  1A1C A;  1CSZ A;  2AOA A;  3VS0 A;  1BHF A;  4JE4 A;  1YVH A;  1OO3 A;  2DX0 A;  1O4L A;  2LQN A;  1AYC A;  1CWD L;  1MW4 A;  4K45 A;  4DGP A;  1AB2 A;  3PFV A;  2B3O A;  1X27 A;  4OHI A;  2KNO A;  1SPR A;  4GWF A;  3N8M A;  1RQQ C;  2CS0 A;  1A07 A;  1KC2 A;  2YU7 A;  2QMS A;  1KA7 A;  3VS6 A;  2CRH A;  4JEG A;  1AYA A;  4M4Z A;  1R1P A;  1R1Q A;  5DC0 B;  5DF6 A;  1O4B A;  4L1B B;  1LCK A;  4FL2 A;  3N84 A;  5DC4 A;  1MIL A;  2GE9 A;  3VS3 A;  4GPL B;  2EKX A;  1Y57 A;  1FU6 A;  4LUD A;  4P9Z A;  2HDV A;  4FBN A;  4E93 A;  1BLK A;  2OZO A;  1NZV A;  1D4W A;  4A4C A;  1HCT B;  3BUX B;  4K2R A;  3BKB A;  4A4B A;  4EY0 A;  3VS2 A;  1NZL A;  4F5A A;  2CBL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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