1O4AA

Crystal structure of sh2 in complex with ru82197.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
molecule tags Signaling protein
source organism Homo sapiens
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4aA00
3VS6A 2AOAA 4A4BA 3CWGA 3HIZB 4DGPA 1K9AA 1LCJA 1MW4A 1YVLA 2YSXA 1LCKA 1SPRA 1O4KA 1FU5A 2JYQA 3OB1B 4U17A 1B47A 5DC4A 1I3ZA 2Y1NA 4GWFA 2DVJA 2IUHA 1LKKA 1Z3KA 3PFVA 2CRHA 4E68A 1AD5A 3VS0A 1O45A 2MK2A 2CS0A 2MRKA 2RSYA 4P9VA 3VS2A 2LQNA 4L1BB 1TZEE 3OP0A 3MXYA 2C9WA 1JYUA 1O41A 1FYRA 3MXCA 3BUNB 3S9KA 1BHHA 3PS5A 3VS3A 1G83A 2H5KA 2CBLA 2PLDA 1TCEA 5KAZA 4OHEA 3PSJA 2GSBA 3VRRA 1O4BA 2HDXA 1JYQA 4FL3A 1O4HA 1O42A 1UUSA 3NHNA 2EO3A 2L6KA 4K11A 1HCTB 1BKMA 3N7YA 2EO6A 1NZVA 1O4CA 1AB2A 3QWYA 3OVEA 3VS4A 1O4PA 5GJIA 3UYOA 3VS7A 3PLFB 1O47A 3VS1A 4K45A 2FCIA 3K2MA 2C0IA 2DLYA 3S8NA 2C0TA 3GXXA 1OO3A 1P13A 1O4IA 4WWQA 4E93A 2HDVA 1D4TA 2L3TA 1CWDL 5CDWA 2RORA 3IN8A 1Y57A 5HKZA 1PICA 2SHPA 1IS0A 1O49A 1R1PA 1FBVA 3VS5A 1A07A 1QCFA 4X6SA 3CD3A 3IMJA 1SKJA 4F5AA 2LNWA 1D4WA 1BHFA 4LUEA 2LCTA 1CWEA 1A09A 4P9ZA 5J3XA 1SPSA 2ETZA 2QMSA 5DF6A 1MILA 5AXIA 1BM2A 3S8LA 3VRZA 1O4RA 4D8KA 1A81A 5BO4A 3PQZA 1LUKA 2MQIA 1Y1UA 1F2FA 5HKYA 1A1BA 1A1CA 2DX0A 3HHMB 5EHPA 2EKXA 1AOTF 1F1WA 1O4FA 3BUMB 3EACA 1JU5A 4M4ZA 1FU6A 2AOBA 2H8HA 1O43A 2Y3AB 1O4JA 5GJHA 4GPLB 1O4OA 1O4QA 1M27A 2DLZA 1O4LA 1X6CA 3CXLA 2EYZA 1WQUA 1FMKA 1SHAA 1QG1E 1A1AA 2RVFA 3GXWA 3CBLA 2KK6A 2CR4A 3BUWB 2ECDA 3VRYA 3TKZA 2K79B 3N84A 1O48A 3HCKA 2OQ1A 3N8MA 3US4A 2EYYA 1YVHA 3C7IA 3BUXB 4OHLA 3VGOA 4OHHA 2EU0A 1NZLA 5EELA 1H9OA 1JYRA 2SRCA 5I6VA 5HKWA 2CIAA 4F59A 4A4CA 1RPYA 2HMHA 4FBNA 1O46A 1BLKA 1KSWA 2XP1A 2PNAA 3MAZA 1O44A 4JEGA 1BFJA 1O4EA 5EEQA 1LUNA 2IUIA 1OO4A 4XZ1A 1QADA 2EOBA 3UF4A 2CI9A 1O4DA 4TZIA 4OHDA 2K7AB 1CSYA 1OPLA 2LNXA 1LUMA 4EY0A 4K44A 2GE9A 3IMDA 4DGXA 3EAZA 4NWFA 1KA7A 5D0JA 1ZFPE 5DC0B 1AYAA 1KA6A 3PSKA 2CI8A 1RJAA 2MC1A 2ABLA 4F5BA 1CSZA 1SHDA 2PTKA 3BKBA 2VIFA 1R1QA 2C0OA 4FL2A 2PNBA 3WA4A 1BFIA 4H1OA 1X0NA 3ZNIA 4GL9E 3M7FA 3VROA 1O4GA 3VRPA 1AYCA 2LQWA 1KC2A 1LKLA 2AUGA 2EL8A 3QWXX 1SHBA 2DCRA 1O4AA 1BHHB 2HUWA 1FHSA 3GQIB 2EYVA 4K2RA 3PJPA 1BG1A 1UURA 1AOUF 1HCSB 2Y1MA 1BF5A 3S8OA 1NRVA 1AYDA 2H46E 1IJRA 1BLJA 2IUGA 3TL0A 1FBZA 3BUOB 3VRQA 5IBSA 5EG3B 2FO0A 4EIHA 3IN7A 2DM0A 4JE4A 4QSYA 2HCKA 1BMBA 4U1PA 4JGHA 1BKLA 2BBUA 1CJ1A 3OB2B 2L4KA 1A08A 1O4MA 1R1SA 4ROJA 1X27A 2YU7A 1GHUA 1GRIA 1JWOA 1AYBA 3OV1A 4XZ0A 4H34A 3KFJA 5IBMA 1XA6A 5EHRA 1LUIA 2OZOA 2B3OA 4LUDA 3T04A 1A1EA 4OHIA 2IZVA 1O4NA 1OPKA 2MRJA 2RMXA 1M61A 4NWGA 2PLEA 1RQQC 5AULA 1D1ZA 2KNOA 5DC9A 3VRNA
chains in the Genus database with same CATH superfamily
3VS6A 2AOAA 4A4BA 3CWGA 3HIZB 4DGPA 1K9AA 1LCJA 1MW4A 1YVLA 2YSXA 1LCKA 1SPRA 1O4KA 1FU5A 2JYQA 3OB1B 4U17A 1B47A 5DC4A 1I3ZA 2Y1NA 4GWFA 2DVJA 2IUHA 1LKKA 1Z3KA 3PFVA 2CRHA 4E68A 1AD5A 3VS0A 1O45A 2MK2A 2CS0A 2MRKA 2RSYA 4P9VA 3VS2A 2LQNA 4L1BB 1TZEE 3OP0A 3MXYA 2C9WA 1JYUA 1O41A 1FYRA 3LYVA 3BUNB 3MXCA 3S9KA 1BHHA 3PS5A 3VS3A 1G83A 2H5KA 2CBLA 2PLDA 1TCEA 5KAZA 4OHEA 3PSJA 2GSBA 3VRRA 1O4BA 2HDXA 1JYQA 4FL3A 1O4HA 1O42A 1UUSA 3NHNA 2EO3A 2L6KA 4K11A 1HCTB 1BKMA 3N7YA 2EO6A 1NZVA 1O4CA 1AB2A 3QWYA 3OVEA 3VS4A 1O4PA 5GJIA 3UYOA 3VS7A 3PLFB 1O47A 3VS1A 4K45A 2FCIA 3K2MA 2C0IA 2DLYA 3S8NA 2C0TA 3GXXA 1OO3A 1P13A 1O4IA 4WWQA 4E93A 2HDVA 1D4TA 2L3TA 1CWDL 5CDWA 2RORA 3IN8A 1Y57A 5HKZA 1PICA 2SHPA 1IS0A 1O49A 1R1PA 1FBVA 3VS5A 1A07A 1QCFA 4X6SA 3CD3A 3IMJA 1SKJA 4F5AA 2LNWA 1D4WA 1BHFA 4LUEA 2LCTA 1CWEA 1A09A 4P9ZA 5J3XA 1SPSA 2ETZA 2QMSA 5DF6A 1MILA 5AXIA 1BM2A 3S8LA 3VRZA 1O4RA 4D8KA 1A81A 5BO4A 3PQZA 1LUKA 2MQIA 1Y1UA 1F2FA 5HKYA 1A1BA 1A1CA 2DX0A 3HHMB 5EHPA 2EKXA 1AOTF 1F1WA 1O4FA 3BUMB 3EACA 1JU5A 4M4ZA 1FU6A 2AOBA 2H8HA 1O43A 2Y3AB 1O4JA 5GJHA 4GPLB 1O4OA 1O4QA 1M27A 2DLZA 1O4LA 1X6CA 3CXLA 2EYZA 1WQUA 1FMKA 1SHAA 1QG1E 1A1AA 2LRAA 2RVFA 3GXWA 3CBLA 2KK6A 2CR4A 3BUWB 2ECDA 3VRYA 3TKZA 2K79B 3N84A 1O48A 3HCKA 2OQ1A 3N8MA 3US4A 2EYYA 1YVHA 3C7IA 3BUXB 4OHLA 3VGOA 4OHHA 2EU0A 1NZLA 5EELA 1H9OA 1JYRA 2SRCA 5I6VA 5HKWA 2CIAA 4F59A 4A4CA 1RPYA 2HMHA 4FBNA 1O46A 1BLKA 1KSWA 2XP1A 2PNAA 3MAZA 1O44A 4JEGA 1BFJA 1O4EA 5EEQA 1LUNA 2IUIA 1OO4A 4XZ1A 1QADA 2EOBA 3UF4A 2CI9A 1O4DA 4TZIA 4OHDA 2K7AB 1CSYA 1OPLA 2LNXA 1LUMA 4EY0A 4K44A 2GE9A 3IMDA 4DGXA 3EAZA 4NWFA 1KA7A 5D0JA 1ZFPE 5DC0B 1AYAA 1KA6A 3PSKA 2CI8A 1RJAA 2MC1A 2ABLA 3K2TA 4F5BA 1CSZA 1SHDA 2PTKA 3BKBA 2VIFA 1R1QA 2C0OA 4FL2A 2PNBA 3WA4A 1BFIA 4H1OA 1X0NA 3ZNIA 4GL9E 3M7FA 3VROA 1O4GA 3VRPA 1AYCA 2LQWA 1KC2A 1LKLA 2AUGA 2EL8A 3QWXX 1SHBA 2DCRA 1O4AA 1BHHB 2HUWA 1FHSA 3GQIB 2EYVA 4K2RA 3PJPA 1BG1A 1UURA 1AOUF 1HCSB 2Y1MA 1BF5A 3S8OA 1NRVA 1AYDA 2H46E 1IJRA 1BLJA 2IUGA 3TL0A 1FBZA 3BUOB 3VRQA 5IBSA 5EG3B 2FO0A 4EIHA 3IN7A 2DM0A 4JE4A 4QSYA 2HCKA 1BMBA 4U1PA 4JGHA 1BKLA 2BBUA 2KGYA 1CJ1A 3OB2B 2L4KA 1A08A 1O4MA 1R1SA 4ROJA 1X27A 2YU7A 1GHUA 1GRIA 1JWOA 1AYBA 3OV1A 4XZ0A 4H34A 3KFJA 5IBMA 1XA6A 5EHRA 1LUIA 2OZOA 2B3OA 4LUDA 3T04A 1A1EA 4OHIA 2IZVA 1O4NA 1OPKA 2MRJA 2RMXA 1M61A 4NWGA 2PLEA 1RQQC 5AULA 1D1ZA 2KNOA 5DC9A 3VRNA
chains in the Genus database with same CATH topology
3VS6A 2AOAA 4A4BA 3CWGA 3HIZB 4DGPA 1K9AA 1LCJA 1MW4A 1YVLA 2YSXA 1LCKA 1SPRA 1O4KA 1FU5A 2JYQA 3OB1B 4U17A 1B47A 5DC4A 1I3ZA 2Y1NA 4GWFA 2DVJA 2IUHA 1LKKA 1Z3KA 3PFVA 2CRHA 4E68A 1AD5A 3VS0A 1O45A 2MK2A 2CS0A 2MRKA 2RSYA 4P9VA 3VS2A 2LQNA 4L1BB 1TZEE 3OP0A 3MXYA 2C9WA 1JYUA 1O41A 1FYRA 3MXCA 3BUNB 3S9KA 1BHHA 3PS5A 3VS3A 1G83A 2H5KA 2CBLA 2PLDA 1TCEA 5KAZA 4OHEA 3PSJA 2GSBA 3VRRA 1O4BA 2HDXA 1JYQA 4FL3A 1O4HA 1O42A 1UUSA 3NHNA 2EO3A 2L6KA 4K11A 1HCTB 1BKMA 3N7YA 2EO6A 1NZVA 1O4CA 1AB2A 3QWYA 3OVEA 3VS4A 1O4PA 5GJIA 3UYOA 3VS7A 3PLFB 1O47A 3VS1A 4K45A 2FCIA 3K2MA 2C0IA 2DLYA 3S8NA 2C0TA 3GXXA 1OO3A 1P13A 1O4IA 4WWQA 4E93A 2HDVA 1D4TA 2L3TA 1CWDL 5CDWA 2RORA 3IN8A 1Y57A 5HKZA 1PICA 2SHPA 1IS0A 1O49A 1R1PA 1FBVA 3VS5A 1A07A 1QCFA 4X6SA 3CD3A 3IMJA 1SKJA 4F5AA 2LNWA 1D4WA 1BHFA 4LUEA 2LCTA 1CWEA 1A09A 4P9ZA 5J3XA 1SPSA 2ETZA 2QMSA 5DF6A 1MILA 5AXIA 1BM2A 3S8LA 3VRZA 1O4RA 4D8KA 1A81A 5BO4A 3PQZA 1LUKA 2MQIA 1Y1UA 1F2FA 5HKYA 1A1BA 1A1CA 2DX0A 3HHMB 5EHPA 2EKXA 1AOTF 1F1WA 1O4FA 3BUMB 3EACA 1JU5A 4M4ZA 1FU6A 2AOBA 2H8HA 1O43A 2Y3AB 1O4JA 5GJHA 4GPLB 1O4OA 1O4QA 1M27A 2DLZA 1O4LA 1X6CA 3CXLA 2EYZA 1WQUA 1FMKA 1SHAA 1QG1E 1A1AA 2RVFA 3GXWA 3CBLA 2KK6A 2CR4A 3BUWB 2ECDA 3VRYA 3TKZA 2K79B 3N84A 1O48A 3HCKA 2OQ1A 3N8MA 3US4A 2EYYA 1YVHA 3C7IA 3BUXB 4OHLA 3VGOA 4OHHA 2EU0A 1NZLA 5EELA 1H9OA 1JYRA 2SRCA 5I6VA 5HKWA 2CIAA 4F59A 4A4CA 1RPYA 2HMHA 4FBNA 1O46A 1BLKA 1KSWA 2XP1A 2PNAA 3MAZA 1O44A 4JEGA 1BFJA 1O4EA 5EEQA 1LUNA 2IUIA 1OO4A 4XZ1A 1QADA 2EOBA 3UF4A 2CI9A 1O4DA 4TZIA 4OHDA 2K7AB 1CSYA 1OPLA 2LNXA 1LUMA 4EY0A 4K44A 2GE9A 3IMDA 4DGXA 3EAZA 4NWFA 1KA7A 5D0JA 1ZFPE 5DC0B 1AYAA 1KA6A 3PSKA 2CI8A 1RJAA 2MC1A 2ABLA 4F5BA 1CSZA 1SHDA 2PTKA 3BKBA 2VIFA 1R1QA 2C0OA 4FL2A 2PNBA 3WA4A 1BFIA 4H1OA 1X0NA 3ZNIA 4GL9E 3M7FA 3VROA 1O4GA 3VRPA 1AYCA 2LQWA 1KC2A 1LKLA 2AUGA 2EL8A 3QWXX 1SHBA 2DCRA 1O4AA 1BHHB 2HUWA 1FHSA 3GQIB 2EYVA 4K2RA 3PJPA 1BG1A 1UURA 1AOUF 1HCSB 2Y1MA 1BF5A 3S8OA 1NRVA 1AYDA 2H46E 1IJRA 1BLJA 2IUGA 3TL0A 1FBZA 3BUOB 3VRQA 5IBSA 5EG3B 2FO0A 4EIHA 3IN7A 2DM0A 4JE4A 4QSYA 2HCKA 1BMBA 4U1PA 4JGHA 1BKLA 2BBUA 1CJ1A 3OB2B 2L4KA 1A08A 1O4MA 1R1SA 4ROJA 1X27A 2YU7A 1GHUA 1GRIA 1JWOA 1AYBA 3OV1A 4XZ0A 4H34A 3KFJA 5IBMA 1XA6A 5EHRA 1LUIA 2OZOA 2B3OA 4LUDA 3T04A 1A1EA 4OHIA 2IZVA 1O4NA 1OPKA 2MRJA 2RMXA 1M61A 4NWGA 2PLEA 1RQQC 5AULA 1D1ZA 2KNOA 5DC9A 3VRNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VS6 A;  2AOA A;  4A4B A;  3CWG A;  3HIZ B;  4DGP A;  1K9A A;  1LCJ A;  1MW4 A;  1YVL A;  2YSX A;  1LCK A;  1SPR A;  1O4K A;  1FU5 A;  2JYQ A;  3OB1 B;  4U17 A;  1B47 A;  5DC4 A;  1I3Z A;  2Y1N A;  4GWF A;  2DVJ A;  2IUH A;  1LKK A;  1Z3K A;  3PFV A;  2CRH A;  4E68 A;  1AD5 A;  3VS0 A;  1O45 A;  2MK2 A;  2CS0 A;  2MRK A;  2RSY A;  4P9V A;  3VS2 A;  2LQN A;  4L1B B;  1TZE E;  3OP0 A;  3MXY A;  2C9W A;  1JYU A;  1O41 A;  1FYR A;  3MXC A;  3BUN B;  3S9K A;  1BHH A;  3PS5 A;  3VS3 A;  1G83 A;  2H5K A;  2CBL A;  2PLD A;  1TCE A;  5KAZ A;  4OHE A;  3PSJ A;  2GSB A;  3VRR A;  1O4B A;  2HDX A;  1JYQ A;  4FL3 A;  1O4H A;  1O42 A;  1UUS A;  3NHN A;  2EO3 A;  2L6K A;  4K11 A;  1HCT B;  1BKM A;  3N7Y A;  2EO6 A;  1NZV A;  1O4C A;  1AB2 A;  3QWY A;  3OVE A;  3VS4 A;  1O4P A;  5GJI A;  3UYO A;  3VS7 A;  3PLF B;  1O47 A;  3VS1 A;  4K45 A;  2FCI A;  3K2M A;  2C0I A;  2DLY A;  3S8N A;  2C0T A;  3GXX A;  1OO3 A;  1P13 A;  1O4I A;  4WWQ A;  4E93 A;  2HDV A;  1D4T A;  2L3T A;  1CWD L;  5CDW A;  2ROR A;  3IN8 A;  1Y57 A;  5HKZ A;  1PIC A;  2SHP A;  1IS0 A;  1O49 A;  1R1P A;  1FBV A;  3VS5 A;  1A07 A;  1QCF A;  4X6S A;  3CD3 A;  3IMJ A;  1SKJ A;  4F5A A;  2LNW A;  1D4W A;  1BHF A;  4LUE A;  2LCT A;  1CWE A;  1A09 A;  4P9Z A;  5J3X A;  1SPS A;  2ETZ A;  2QMS A;  5DF6 A;  1MIL A;  5AXI A;  1BM2 A;  3S8L A;  3VRZ A;  1O4R A;  4D8K A;  1A81 A;  5BO4 A;  3PQZ A;  1LUK A;  2MQI A;  1Y1U A;  1F2F A;  5HKY A;  1A1B A;  1A1C A;  2DX0 A;  3HHM B;  5EHP A;  2EKX A;  1AOT F;  1F1W A;  1O4F A;  3BUM B;  3EAC A;  1JU5 A;  4M4Z A;  1FU6 A;  2AOB A;  2H8H A;  1O43 A;  2Y3A B;  1O4J A;  5GJH A;  4GPL B;  1O4O A;  1O4Q A;  1M27 A;  2DLZ A;  1O4L A;  1X6C A;  3CXL A;  2EYZ A;  1WQU A;  1FMK A;  1SHA A;  1QG1 E;  1A1A A;  2RVF A;  3GXW A;  3CBL A;  2KK6 A;  2CR4 A;  3BUW B;  2ECD A;  3VRY A;  3TKZ A;  2K79 B;  3N84 A;  1O48 A;  3HCK A;  2OQ1 A;  3N8M A;  3US4 A;  2EYY A;  1YVH A;  3C7I A;  3BUX B;  4OHL A;  3VGO A;  4OHH A;  2EU0 A;  1NZL A;  5EEL A;  1H9O A;  1JYR A;  2SRC A;  5I6V A;  5HKW A;  2CIA A;  4F59 A;  4A4C A;  1RPY A;  2HMH A;  4FBN A;  1O46 A;  1BLK A;  1KSW A;  2XP1 A;  2PNA A;  3MAZ A;  1O44 A;  4JEG A;  1BFJ A;  1O4E A;  5EEQ A;  1LUN A;  2IUI A;  1OO4 A;  4XZ1 A;  1QAD A;  2EOB A;  3UF4 A;  2CI9 A;  1O4D A;  4TZI A;  4OHD A;  2K7A B;  1CSY A;  1OPL A;  2LNX A;  1LUM A;  4EY0 A;  4K44 A;  2GE9 A;  3IMD A;  4DGX A;  3EAZ A;  4NWF A;  1KA7 A;  5D0J A;  1ZFP E;  5DC0 B;  1AYA A;  1KA6 A;  3PSK A;  2CI8 A;  1RJA A;  2MC1 A;  2ABL A;  4F5B A;  1CSZ A;  1SHD A;  2PTK A;  3BKB A;  2VIF A;  1R1Q A;  2C0O A;  4FL2 A;  2PNB A;  3WA4 A;  1BFI A;  4H1O A;  1X0N A;  3ZNI A;  4GL9 E;  3M7F A;  3VRO A;  1O4G A;  3VRP A;  1AYC A;  2LQW A;  1KC2 A;  1LKL A;  2AUG A;  2EL8 A;  3QWX X;  1SHB A;  2DCR A;  1O4A A;  1BHH B;  2HUW A;  1FHS A;  3GQI B;  2EYV A;  4K2R A;  3PJP A;  1BG1 A;  1UUR A;  1AOU F;  1HCS B;  2Y1M A;  1BF5 A;  3S8O A;  1NRV A;  1AYD A;  2H46 E;  1IJR A;  1BLJ A;  2IUG A;  3TL0 A;  1FBZ A;  3BUO B;  3VRQ A;  5IBS A;  5EG3 B;  2FO0 A;  4EIH A;  3IN7 A;  2DM0 A;  4JE4 A;  4QSY A;  2HCK A;  1BMB A;  4U1P A;  4JGH A;  1BKL A;  2BBU A;  1CJ1 A;  3OB2 B;  2L4K A;  1A08 A;  1O4M A;  1R1S A;  4ROJ A;  1X27 A;  2YU7 A;  1GHU A;  1GRI A;  1JWO A;  1AYB A;  3OV1 A;  4XZ0 A;  4H34 A;  3KFJ A;  5IBM A;  1XA6 A;  5EHR A;  1LUI A;  2OZO A;  2B3O A;  4LUD A;  3T04 A;  1A1E A;  4OHI A;  2IZV A;  1O4N A;  1OPK A;  2MRJ A;  2RMX A;  1M61 A;  4NWG A;  2PLE A;  1RQQ C;  5AUL A;  1D1Z A;  2KNO A;  5DC9 A;  3VRN A; 
#chains in the Genus database with same CATH topology
 3VS6 A;  2AOA A;  4A4B A;  3CWG A;  3HIZ B;  4DGP A;  1K9A A;  1LCJ A;  1MW4 A;  1YVL A;  2YSX A;  1LCK A;  1SPR A;  1O4K A;  1FU5 A;  2JYQ A;  3OB1 B;  4U17 A;  1B47 A;  5DC4 A;  1I3Z A;  2Y1N A;  4GWF A;  2DVJ A;  2IUH A;  1LKK A;  1Z3K A;  3PFV A;  2CRH A;  4E68 A;  1AD5 A;  3VS0 A;  1O45 A;  2MK2 A;  2CS0 A;  2MRK A;  2RSY A;  4P9V A;  3VS2 A;  2LQN A;  4L1B B;  1TZE E;  3OP0 A;  3MXY A;  2C9W A;  1JYU A;  1O41 A;  1FYR A;  3LYV A;  3BUN B;  3MXC A;  3S9K A;  1BHH A;  3PS5 A;  3VS3 A;  1G83 A;  2H5K A;  2CBL A;  2PLD A;  1TCE A;  5KAZ A;  4OHE A;  3PSJ A;  2GSB A;  3VRR A;  1O4B A;  2HDX A;  1JYQ A;  4FL3 A;  1O4H A;  1O42 A;  1UUS A;  3NHN A;  2EO3 A;  2L6K A;  4K11 A;  1HCT B;  1BKM A;  3N7Y A;  2EO6 A;  1NZV A;  1O4C A;  1AB2 A;  3QWY A;  3OVE A;  3VS4 A;  1O4P A;  5GJI A;  3UYO A;  3VS7 A;  3PLF B;  1O47 A;  3VS1 A;  4K45 A;  2FCI A;  3K2M A;  2C0I A;  2DLY A;  3S8N A;  2C0T A;  3GXX A;  1OO3 A;  1P13 A;  1O4I A;  4WWQ A;  4E93 A;  2HDV A;  1D4T A;  2L3T A;  1CWD L;  5CDW A;  2ROR A;  3IN8 A;  1Y57 A;  5HKZ A;  1PIC A;  2SHP A;  1IS0 A;  1O49 A;  1R1P A;  1FBV A;  3VS5 A;  1A07 A;  1QCF A;  4X6S A;  3CD3 A;  3IMJ A;  1SKJ A;  4F5A A;  2LNW A;  1D4W A;  1BHF A;  4LUE A;  2LCT A;  1CWE A;  1A09 A;  4P9Z A;  5J3X A;  1SPS A;  2ETZ A;  2QMS A;  5DF6 A;  1MIL A;  5AXI A;  1BM2 A;  3S8L A;  3VRZ A;  1O4R A;  4D8K A;  1A81 A;  5BO4 A;  3PQZ A;  1LUK A;  2MQI A;  1Y1U A;  1F2F A;  5HKY A;  1A1B A;  1A1C A;  2DX0 A;  3HHM B;  5EHP A;  2EKX A;  1AOT F;  1F1W A;  1O4F A;  3BUM B;  3EAC A;  1JU5 A;  4M4Z A;  1FU6 A;  2AOB A;  2H8H A;  1O43 A;  2Y3A B;  1O4J A;  5GJH A;  4GPL B;  1O4O A;  1O4Q A;  1M27 A;  2DLZ A;  1O4L A;  1X6C A;  3CXL A;  2EYZ A;  1WQU A;  1FMK A;  1SHA A;  1QG1 E;  1A1A A;  2LRA A;  2RVF A;  3GXW A;  3CBL A;  2KK6 A;  2CR4 A;  3BUW B;  2ECD A;  3VRY A;  3TKZ A;  2K79 B;  3N84 A;  1O48 A;  3HCK A;  2OQ1 A;  3N8M A;  3US4 A;  2EYY A;  1YVH A;  3C7I A;  3BUX B;  4OHL A;  3VGO A;  4OHH A;  2EU0 A;  1NZL A;  5EEL A;  1H9O A;  1JYR A;  2SRC A;  5I6V A;  5HKW A;  2CIA A;  4F59 A;  4A4C A;  1RPY A;  2HMH A;  4FBN A;  1O46 A;  1BLK A;  1KSW A;  2XP1 A;  2PNA A;  3MAZ A;  1O44 A;  4JEG A;  1BFJ A;  1O4E A;  5EEQ A;  1LUN A;  2IUI A;  1OO4 A;  4XZ1 A;  1QAD A;  2EOB A;  3UF4 A;  2CI9 A;  1O4D A;  4TZI A;  4OHD A;  2K7A B;  1CSY A;  1OPL A;  2LNX A;  1LUM A;  4EY0 A;  4K44 A;  2GE9 A;  3IMD A;  4DGX A;  3EAZ A;  4NWF A;  1KA7 A;  5D0J A;  1ZFP E;  5DC0 B;  1AYA A;  1KA6 A;  3PSK A;  2CI8 A;  1RJA A;  2MC1 A;  2ABL A;  3K2T A;  4F5B A;  1CSZ A;  1SHD A;  2PTK A;  3BKB A;  2VIF A;  1R1Q A;  2C0O A;  4FL2 A;  2PNB A;  3WA4 A;  1BFI A;  4H1O A;  1X0N A;  3ZNI A;  4GL9 E;  3M7F A;  3VRO A;  1O4G A;  3VRP A;  1AYC A;  2LQW A;  1KC2 A;  1LKL A;  2AUG A;  2EL8 A;  3QWX X;  1SHB A;  2DCR A;  1O4A A;  1BHH B;  2HUW A;  1FHS A;  3GQI B;  2EYV A;  4K2R A;  3PJP A;  1BG1 A;  1UUR A;  1AOU F;  1HCS B;  2Y1M A;  1BF5 A;  3S8O A;  1NRV A;  1AYD A;  2H46 E;  1IJR A;  1BLJ A;  2IUG A;  3TL0 A;  1FBZ A;  3BUO B;  3VRQ A;  5IBS A;  5EG3 B;  2FO0 A;  4EIH A;  3IN7 A;  2DM0 A;  4JE4 A;  4QSY A;  2HCK A;  1BMB A;  4U1P A;  4JGH A;  1BKL A;  2BBU A;  2KGY A;  1CJ1 A;  3OB2 B;  2L4K A;  1A08 A;  1O4M A;  1R1S A;  4ROJ A;  1X27 A;  2YU7 A;  1GHU A;  1GRI A;  1JWO A;  1AYB A;  3OV1 A;  4XZ0 A;  4H34 A;  3KFJ A;  5IBM A;  1XA6 A;  5EHR A;  1LUI A;  2OZO A;  2B3O A;  4LUD A;  3T04 A;  1A1E A;  4OHI A;  2IZV A;  1O4N A;  1OPK A;  2MRJ A;  2RMX A;  1M61 A;  4NWG A;  2PLE A;  1RQQ C;  5AUL A;  1D1Z A;  2KNO A;  5DC9 A;  3VRN A; 
#chains in the Genus database with same CATH homology
 3VS6 A;  2AOA A;  4A4B A;  3CWG A;  3HIZ B;  4DGP A;  1K9A A;  1LCJ A;  1MW4 A;  1YVL A;  2YSX A;  1LCK A;  1SPR A;  1O4K A;  1FU5 A;  2JYQ A;  3OB1 B;  4U17 A;  1B47 A;  5DC4 A;  1I3Z A;  2Y1N A;  4GWF A;  2DVJ A;  2IUH A;  1LKK A;  1Z3K A;  3PFV A;  2CRH A;  4E68 A;  1AD5 A;  3VS0 A;  1O45 A;  2MK2 A;  2CS0 A;  2MRK A;  2RSY A;  4P9V A;  3VS2 A;  2LQN A;  4L1B B;  1TZE E;  3OP0 A;  3MXY A;  2C9W A;  1JYU A;  1O41 A;  1FYR A;  3MXC A;  3BUN B;  3S9K A;  1BHH A;  3PS5 A;  3VS3 A;  1G83 A;  2H5K A;  2CBL A;  2PLD A;  1TCE A;  5KAZ A;  4OHE A;  3PSJ A;  2GSB A;  3VRR A;  1O4B A;  2HDX A;  1JYQ A;  4FL3 A;  1O4H A;  1O42 A;  1UUS A;  3NHN A;  2EO3 A;  2L6K A;  4K11 A;  1HCT B;  1BKM A;  3N7Y A;  2EO6 A;  1NZV A;  1O4C A;  1AB2 A;  3QWY A;  3OVE A;  3VS4 A;  1O4P A;  5GJI A;  3UYO A;  3VS7 A;  3PLF B;  1O47 A;  3VS1 A;  4K45 A;  2FCI A;  3K2M A;  2C0I A;  2DLY A;  3S8N A;  2C0T A;  3GXX A;  1OO3 A;  1P13 A;  1O4I A;  4WWQ A;  4E93 A;  2HDV A;  1D4T A;  2L3T A;  1CWD L;  5CDW A;  2ROR A;  3IN8 A;  1Y57 A;  5HKZ A;  1PIC A;  2SHP A;  1IS0 A;  1O49 A;  1R1P A;  1FBV A;  3VS5 A;  1A07 A;  1QCF A;  4X6S A;  3CD3 A;  3IMJ A;  1SKJ A;  4F5A A;  2LNW A;  1D4W A;  1BHF A;  4LUE A;  2LCT A;  1CWE A;  1A09 A;  4P9Z A;  5J3X A;  1SPS A;  2ETZ A;  2QMS A;  5DF6 A;  1MIL A;  5AXI A;  1BM2 A;  3S8L A;  3VRZ A;  1O4R A;  4D8K A;  1A81 A;  5BO4 A;  3PQZ A;  1LUK A;  2MQI A;  1Y1U A;  1F2F A;  5HKY A;  1A1B A;  1A1C A;  2DX0 A;  3HHM B;  5EHP A;  2EKX A;  1AOT F;  1F1W A;  1O4F A;  3BUM B;  3EAC A;  1JU5 A;  4M4Z A;  1FU6 A;  2AOB A;  2H8H A;  1O43 A;  2Y3A B;  1O4J A;  5GJH A;  4GPL B;  1O4O A;  1O4Q A;  1M27 A;  2DLZ A;  1O4L A;  1X6C A;  3CXL A;  2EYZ A;  1WQU A;  1FMK A;  1SHA A;  1QG1 E;  1A1A A;  2RVF A;  3GXW A;  3CBL A;  2KK6 A;  2CR4 A;  3BUW B;  2ECD A;  3VRY A;  3TKZ A;  2K79 B;  3N84 A;  1O48 A;  3HCK A;  2OQ1 A;  3N8M A;  3US4 A;  2EYY A;  1YVH A;  3C7I A;  3BUX B;  4OHL A;  3VGO A;  4OHH A;  2EU0 A;  1NZL A;  5EEL A;  1H9O A;  1JYR A;  2SRC A;  5I6V A;  5HKW A;  2CIA A;  4F59 A;  4A4C A;  1RPY A;  2HMH A;  4FBN A;  1O46 A;  1BLK A;  1KSW A;  2XP1 A;  2PNA A;  3MAZ A;  1O44 A;  4JEG A;  1BFJ A;  1O4E A;  5EEQ A;  1LUN A;  2IUI A;  1OO4 A;  4XZ1 A;  1QAD A;  2EOB A;  3UF4 A;  2CI9 A;  1O4D A;  4TZI A;  4OHD A;  2K7A B;  1CSY A;  1OPL A;  2LNX A;  1LUM A;  4EY0 A;  4K44 A;  2GE9 A;  3IMD A;  4DGX A;  3EAZ A;  4NWF A;  1KA7 A;  5D0J A;  1ZFP E;  5DC0 B;  1AYA A;  1KA6 A;  3PSK A;  2CI8 A;  1RJA A;  2MC1 A;  2ABL A;  4F5B A;  1CSZ A;  1SHD A;  2PTK A;  3BKB A;  2VIF A;  1R1Q A;  2C0O A;  4FL2 A;  2PNB A;  3WA4 A;  1BFI A;  4H1O A;  1X0N A;  3ZNI A;  4GL9 E;  3M7F A;  3VRO A;  1O4G A;  3VRP A;  1AYC A;  2LQW A;  1KC2 A;  1LKL A;  2AUG A;  2EL8 A;  3QWX X;  1SHB A;  2DCR A;  1O4A A;  1BHH B;  2HUW A;  1FHS A;  3GQI B;  2EYV A;  4K2R A;  3PJP A;  1BG1 A;  1UUR A;  1AOU F;  1HCS B;  2Y1M A;  1BF5 A;  3S8O A;  1NRV A;  1AYD A;  2H46 E;  1IJR A;  1BLJ A;  2IUG A;  3TL0 A;  1FBZ A;  3BUO B;  3VRQ A;  5IBS A;  5EG3 B;  2FO0 A;  4EIH A;  3IN7 A;  2DM0 A;  4JE4 A;  4QSY A;  2HCK A;  1BMB A;  4U1P A;  4JGH A;  1BKL A;  2BBU A;  1CJ1 A;  3OB2 B;  2L4K A;  1A08 A;  1O4M A;  1R1S A;  4ROJ A;  1X27 A;  2YU7 A;  1GHU A;  1GRI A;  1JWO A;  1AYB A;  3OV1 A;  4XZ0 A;  4H34 A;  3KFJ A;  5IBM A;  1XA6 A;  5EHR A;  1LUI A;  2OZO A;  2B3O A;  4LUD A;  3T04 A;  1A1E A;  4OHI A;  2IZV A;  1O4N A;  1OPK A;  2MRJ A;  2RMX A;  1M61 A;  4NWG A;  2PLE A;  1RQQ C;  5AUL A;  1D1Z A;  2KNO A;  5DC9 A;  3VRN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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