1JYUA

Xray structure of grb2 sh2 domain
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
96
structure length
96
Chain Sequence
GSMAWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
total genus 17
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2001-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1jyuA00
1A1BA 4F5AA 1JYRA 3VS5A 3OB2B 1JYQA 2MC1A 1IJRA 1BM2A 1O4LA 3PFVA 2RMXA 1O4PA 2EYZA 3HCKA 2SHPA 2DLZA 3VROA 3VS4A 2BBUA 4LUDA 1AYAA 1G83A 3C7IA 3EACA 2HMHA 4DGPA 1O4JA 1Z3KA 3CD3A 2DVJA 3T04A 4XZ1A 4JE4A 1R1SA 2H46E 2RSYA 2L3TA 3ZNIA 2PNBA 4EY0A 3OB1B 2EYVA 2IUIA 4FL2A 1O48A 3BUXB 1F2FA 1AYCA 2PTKA 1FMKA 2VIFA 5EHPA 1FYRA 1TZEE 4XZ0A 2EOBA 1LUMA 3MXCA 1OPLA 1O47A 5GJHA 2EO3A 5IBSA 1ZFPE 5KAZA 1CWDL 5HKWA 4A4BA 3S8OA 1MW4A 2H5KA 3VRPA 2ABLA 1O4QA 4FL3A 2EO6A 4X6SA 1JU5A 1OPKA 2KK6A 4H1OA 3VRZA 3HIZB 3BUWB 3VGOA 3IMJA 2MRKA 1PICA 4K44A 2EYYA 4E93A 2MQIA 2CRHA 3UYOA 1B47A 1O4IA 1R1PA 4GL9E 1AOUF 4U1PA 4LUEA 3VS7A 3N84A 1BFIA 3PQZA 1O4AA 2HDXA 3BUOB 3GXXA 1M27A 5DC9A 4EIHA 3VRNA 2DX0A 1O4KA 2XP1A 1Y57A 1O4EA 1YVLA 1O44A 2CI9A 3PS5A 2GSBA 3MXYA 3M7FA 2HCKA 1F1WA 1CWEA 1SHDA 2ECDA 2B3OA 1O41A 1LUIA 1SHAA 1NRVA 1KA7A 1BFJA 2IUGA 2ETZA 2RORA 1BHHB 2Y3AB 1GHUA 1BG1A 2CIAA 1UURA 3VS3A 2PLDA 3VS0A 2AUGA 5I6VA 4A4CA 5GJIA 1KA6A 1P13A 2EL8A 1JYUA 4FBNA 1O45A 3BKBA 4OHDA 3VS1A 1BMBA 5AXIA 3IMDA 3WA4A 5HKZA 2QMSA 1OO3A 2C0IA 5CDWA 3GQIB 5DC4A 5BO4A 2K79B 3KFJA 1LKLA 1AYDA 1O4MA 1O4BA 2IUHA 1BHHA 1A08A 1FHSA 3VRQA 4QSYA 2MK2A 3CBLA 2C0TA 1NZLA 3PLFB 5J3XA 2HUWA 5DC0B 1D1ZA 3BUMB 1FU5A 1QCFA 2OQ1A 2EU0A 2CBLA 3K2MA 2HDVA 4D8KA 1O4FA 3VRYA 2AOBA 3BUNB 4F59A 5HKYA 2DM0A 2GE9A 2FCIA 1BLKA 3VS6A 3PSJA 1HCSB 3VS2A 2CR4A 2LNWA 1BHFA 1SPSA 1AOTF 1O4GA 4F5BA 3CWGA 3S8NA 2H8HA 1BLJA 5AULA 3QWXX 2K7AB 3US4A 1FU6A 1UUSA 1LKKA 2L6KA 1XA6A 1FBVA 3N7YA 1SKJA 1KSWA 3VRRA 5EG3B 5D0JA 4WWQA 1AYBA 1A07A 2FO0A 3OV1A 4TZIA 1O4CA 5EHRA 1X0NA 1A81A 2Y1MA 4GWFA 3IN8A 4M4ZA 2PNAA 2LQWA 4JGHA 4OHIA 1QG1E 1BKLA 1LCJA 1FBZA 4GPLB 3MAZA 3GXWA 1O46A 3S8LA 1CJ1A 1A1AA 2LCTA 1LUNA 1O4RA 1IS0A 1BKMA 4JEGA 2C9WA 2SRCA 4P9VA 1AD5A 1OO4A 2Y1NA 3PSKA 1HCTB 1O42A 1NZVA 4NWGA 1K9AA 4DGXA 4H34A 1O4NA 1H9OA 4OHLA 3HHMB 1GRIA 2JYQA 2C0OA 1LUKA 3TKZA 1O4HA 2PLEA 3OVEA 1TCEA 2DCRA 1QADA 1O4DA 3EAZA 4K11A 2IZVA 1Y1UA 4E68A 1D4TA 3UF4A 1O4OA 2CI8A 1KC2A 3OP0A 5EELA 3QWYA 3IN7A 2OZOA 4OHHA 1CSZA 2CS0A 2LNXA 2LQNA 4K45A 5IBMA 1X27A 4U17A 1YVHA 1R1QA 1D4WA 4K2RA 1RQQC 3TL0A 1SHBA 2MRJA 2YU7A 3N8MA 1A1EA 5DF6A 5EEQA 3S9KA 1M61A 3PJPA 4L1BB 1SPRA 1RPYA 2DLYA 1X6CA 4NWFA 1O49A 4OHEA 1A09A 1RJAA 1BF5A 1AB2A 1CSYA 1WQUA 2YSXA 1JWOA 4P9ZA 1A1CA 1LCKA 2EKXA 2L4KA 1MILA 2KNOA 4ROJA 2RVFA 2AOAA 1I3ZA 3CXLA 3NHNA 1O43A
chains in the Genus database with same CATH superfamily
1A1BA 4F5AA 1JYRA 3VS5A 3OB2B 1JYQA 2MC1A 1IJRA 1BM2A 1O4LA 3PFVA 2RMXA 1O4PA 2EYZA 3HCKA 2SHPA 2DLZA 3VROA 3VS4A 2BBUA 4LUDA 1AYAA 1G83A 3C7IA 3EACA 2HMHA 4DGPA 1O4JA 1Z3KA 3CD3A 2DVJA 3T04A 4XZ1A 4JE4A 1R1SA 2H46E 2RSYA 2L3TA 3ZNIA 2PNBA 4EY0A 3OB1B 2EYVA 2IUIA 4FL2A 1O48A 3BUXB 1F2FA 1AYCA 2PTKA 1FMKA 2VIFA 5EHPA 1FYRA 1TZEE 4XZ0A 2EOBA 1LUMA 3MXCA 1OPLA 1O47A 5GJHA 2EO3A 5IBSA 1ZFPE 5KAZA 1CWDL 5HKWA 4A4BA 3S8OA 1MW4A 2H5KA 3VRPA 2ABLA 1O4QA 4FL3A 2EO6A 4X6SA 1JU5A 1OPKA 2KK6A 4H1OA 3VRZA 3HIZB 3BUWB 3VGOA 3IMJA 2MRKA 1PICA 4K44A 2EYYA 4E93A 2MQIA 2CRHA 3UYOA 1B47A 1O4IA 1R1PA 4GL9E 1AOUF 4U1PA 4LUEA 3VS7A 3N84A 1BFIA 3PQZA 1O4AA 2HDXA 3BUOB 3GXXA 1M27A 5DC9A 4EIHA 3VRNA 2DX0A 1O4KA 2XP1A 1Y57A 1O4EA 1YVLA 1O44A 2CI9A 3PS5A 2GSBA 3MXYA 3M7FA 2HCKA 1F1WA 1CWEA 1SHDA 2ECDA 2B3OA 1O41A 1LUIA 1SHAA 1NRVA 1KA7A 1BFJA 2IUGA 2ETZA 2RORA 1BHHB 2Y3AB 1GHUA 1BG1A 2CIAA 1UURA 3VS3A 2PLDA 3VS0A 2AUGA 5I6VA 4A4CA 5GJIA 1KA6A 1P13A 2EL8A 1JYUA 4FBNA 1O45A 3BKBA 4OHDA 3VS1A 1BMBA 5AXIA 3IMDA 3WA4A 5HKZA 2QMSA 1OO3A 2C0IA 5CDWA 3GQIB 5DC4A 5BO4A 2K79B 3KFJA 1LKLA 1AYDA 1O4MA 1O4BA 2IUHA 1BHHA 1A08A 1FHSA 3VRQA 4QSYA 2MK2A 3CBLA 2C0TA 1NZLA 3PLFB 5J3XA 2HUWA 5DC0B 1D1ZA 3BUMB 1FU5A 1QCFA 2OQ1A 2EU0A 2CBLA 3K2MA 2HDVA 4D8KA 1O4FA 3VRYA 2AOBA 3BUNB 4F59A 5HKYA 2DM0A 2GE9A 2KGYA 2FCIA 1BLKA 3VS6A 3PSJA 1HCSB 3VS2A 2CR4A 2LNWA 1BHFA 1SPSA 1AOTF 1O4GA 4F5BA 3CWGA 3S8NA 2H8HA 1BLJA 5AULA 3QWXX 2K7AB 3US4A 1FU6A 1UUSA 1LKKA 2L6KA 1XA6A 1FBVA 3N7YA 1SKJA 1KSWA 3VRRA 5EG3B 5D0JA 4WWQA 1AYBA 1A07A 2FO0A 3OV1A 4TZIA 1O4CA 5EHRA 1X0NA 1A81A 2Y1MA 4GWFA 3IN8A 4M4ZA 2PNAA 2LQWA 4JGHA 4OHIA 1QG1E 1BKLA 1LCJA 2LRAA 1FBZA 4GPLB 3MAZA 3GXWA 1O46A 3S8LA 1CJ1A 1A1AA 2LCTA 1LUNA 1O4RA 1IS0A 1BKMA 4JEGA 2C9WA 2SRCA 4P9VA 1AD5A 1OO4A 2Y1NA 3PSKA 1HCTB 1O42A 1NZVA 4NWGA 1K9AA 4DGXA 4H34A 1O4NA 1H9OA 4OHLA 3HHMB 1GRIA 2JYQA 2C0OA 1LUKA 3TKZA 1O4HA 2PLEA 3OVEA 1TCEA 2DCRA 1QADA 1O4DA 3EAZA 4K11A 2IZVA 1Y1UA 4E68A 1D4TA 3UF4A 1O4OA 2CI8A 1KC2A 3OP0A 5EELA 3QWYA 3IN7A 2OZOA 4OHHA 1CSZA 2CS0A 2LNXA 2LQNA 4K45A 5IBMA 1X27A 4U17A 1YVHA 1R1QA 1D4WA 4K2RA 1RQQC 3TL0A 1SHBA 2MRJA 2YU7A 3N8MA 3K2TA 1A1EA 5DF6A 3LYVA 5EEQA 3S9KA 1M61A 3PJPA 4L1BB 1SPRA 1RPYA 2DLYA 1X6CA 4NWFA 1O49A 4OHEA 1A09A 1RJAA 1BF5A 1AB2A 1CSYA 1WQUA 2YSXA 1JWOA 4P9ZA 1A1CA 1LCKA 2EKXA 2L4KA 1MILA 2KNOA 4ROJA 2RVFA 2AOAA 1I3ZA 3CXLA 3NHNA 1O43A
chains in the Genus database with same CATH topology
1A1BA 4F5AA 1JYRA 3VS5A 3OB2B 1JYQA 2MC1A 1IJRA 1BM2A 1O4LA 3PFVA 2RMXA 1O4PA 2EYZA 3HCKA 2SHPA 2DLZA 3VROA 3VS4A 2BBUA 4LUDA 1AYAA 1G83A 3C7IA 3EACA 2HMHA 4DGPA 1O4JA 1Z3KA 3CD3A 2DVJA 3T04A 4XZ1A 4JE4A 1R1SA 2H46E 2RSYA 2L3TA 3ZNIA 2PNBA 4EY0A 3OB1B 2EYVA 2IUIA 4FL2A 1O48A 3BUXB 1F2FA 1AYCA 2PTKA 1FMKA 2VIFA 5EHPA 1FYRA 1TZEE 4XZ0A 2EOBA 1LUMA 3MXCA 1OPLA 1O47A 5GJHA 2EO3A 5IBSA 1ZFPE 5KAZA 1CWDL 5HKWA 4A4BA 3S8OA 1MW4A 2H5KA 3VRPA 2ABLA 1O4QA 4FL3A 2EO6A 4X6SA 1JU5A 1OPKA 2KK6A 4H1OA 3VRZA 3HIZB 3BUWB 3VGOA 3IMJA 2MRKA 1PICA 4K44A 2EYYA 4E93A 2MQIA 2CRHA 3UYOA 1B47A 1O4IA 1R1PA 4GL9E 1AOUF 4U1PA 4LUEA 3VS7A 3N84A 1BFIA 3PQZA 1O4AA 2HDXA 3BUOB 3GXXA 1M27A 5DC9A 4EIHA 3VRNA 2DX0A 1O4KA 2XP1A 1Y57A 1O4EA 1YVLA 1O44A 2CI9A 3PS5A 2GSBA 3MXYA 3M7FA 2HCKA 1F1WA 1CWEA 1SHDA 2ECDA 2B3OA 1O41A 1LUIA 1SHAA 1NRVA 1KA7A 1BFJA 2IUGA 2ETZA 2RORA 1BHHB 2Y3AB 1GHUA 1BG1A 2CIAA 1UURA 3VS3A 2PLDA 3VS0A 2AUGA 5I6VA 4A4CA 5GJIA 1KA6A 1P13A 2EL8A 1JYUA 4FBNA 1O45A 3BKBA 4OHDA 3VS1A 1BMBA 5AXIA 3IMDA 3WA4A 5HKZA 2QMSA 1OO3A 2C0IA 5CDWA 3GQIB 5DC4A 5BO4A 2K79B 3KFJA 1LKLA 1AYDA 1O4MA 1O4BA 2IUHA 1BHHA 1A08A 1FHSA 3VRQA 4QSYA 2MK2A 3CBLA 2C0TA 1NZLA 3PLFB 5J3XA 2HUWA 5DC0B 1D1ZA 3BUMB 1FU5A 1QCFA 2OQ1A 2EU0A 2CBLA 3K2MA 2HDVA 4D8KA 1O4FA 3VRYA 2AOBA 3BUNB 4F59A 5HKYA 2DM0A 2GE9A 2FCIA 1BLKA 3VS6A 3PSJA 1HCSB 3VS2A 2CR4A 2LNWA 1BHFA 1SPSA 1AOTF 1O4GA 4F5BA 3CWGA 3S8NA 2H8HA 1BLJA 5AULA 3QWXX 2K7AB 3US4A 1FU6A 1UUSA 1LKKA 2L6KA 1XA6A 1FBVA 3N7YA 1SKJA 1KSWA 3VRRA 5EG3B 5D0JA 4WWQA 1AYBA 1A07A 2FO0A 3OV1A 4TZIA 1O4CA 5EHRA 1X0NA 1A81A 2Y1MA 4GWFA 3IN8A 4M4ZA 2PNAA 2LQWA 4JGHA 4OHIA 1QG1E 1BKLA 1LCJA 1FBZA 4GPLB 3MAZA 3GXWA 1O46A 3S8LA 1CJ1A 1A1AA 2LCTA 1LUNA 1O4RA 1IS0A 1BKMA 4JEGA 2C9WA 2SRCA 4P9VA 1AD5A 1OO4A 2Y1NA 3PSKA 1HCTB 1O42A 1NZVA 4NWGA 1K9AA 4DGXA 4H34A 1O4NA 1H9OA 4OHLA 3HHMB 1GRIA 2JYQA 2C0OA 1LUKA 3TKZA 1O4HA 2PLEA 3OVEA 1TCEA 2DCRA 1QADA 1O4DA 3EAZA 4K11A 2IZVA 1Y1UA 4E68A 1D4TA 3UF4A 1O4OA 2CI8A 1KC2A 3OP0A 5EELA 3QWYA 3IN7A 2OZOA 4OHHA 1CSZA 2CS0A 2LNXA 2LQNA 4K45A 5IBMA 1X27A 4U17A 1YVHA 1R1QA 1D4WA 4K2RA 1RQQC 3TL0A 1SHBA 2MRJA 2YU7A 3N8MA 1A1EA 5DF6A 5EEQA 3S9KA 1M61A 3PJPA 4L1BB 1SPRA 1RPYA 2DLYA 1X6CA 4NWFA 1O49A 4OHEA 1A09A 1RJAA 1BF5A 1AB2A 1CSYA 1WQUA 2YSXA 1JWOA 4P9ZA 1A1CA 1LCKA 2EKXA 2L4KA 1MILA 2KNOA 4ROJA 2RVFA 2AOAA 1I3ZA 3CXLA 3NHNA 1O43A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A1B A;  4F5A A;  1JYR A;  3VS5 A;  3OB2 B;  1JYQ A;  2MC1 A;  1IJR A;  1BM2 A;  1O4L A;  3PFV A;  2RMX A;  1O4P A;  2EYZ A;  3HCK A;  2SHP A;  2DLZ A;  3VRO A;  3VS4 A;  2BBU A;  4LUD A;  1AYA A;  1G83 A;  3C7I A;  3EAC A;  2HMH A;  4DGP A;  1O4J A;  1Z3K A;  3CD3 A;  2DVJ A;  3T04 A;  4XZ1 A;  4JE4 A;  1R1S A;  2H46 E;  2RSY A;  2L3T A;  3ZNI A;  2PNB A;  4EY0 A;  3OB1 B;  2EYV A;  2IUI A;  4FL2 A;  1O48 A;  3BUX B;  1F2F A;  1AYC A;  2PTK A;  1FMK A;  2VIF A;  5EHP A;  1FYR A;  1TZE E;  4XZ0 A;  2EOB A;  1LUM A;  3MXC A;  1OPL A;  1O47 A;  5GJH A;  2EO3 A;  5IBS A;  1ZFP E;  5KAZ A;  1CWD L;  5HKW A;  4A4B A;  3S8O A;  1MW4 A;  2H5K A;  3VRP A;  2ABL A;  1O4Q A;  4FL3 A;  2EO6 A;  4X6S A;  1JU5 A;  1OPK A;  2KK6 A;  4H1O A;  3VRZ A;  3HIZ B;  3BUW B;  3VGO A;  3IMJ A;  2MRK A;  1PIC A;  4K44 A;  2EYY A;  4E93 A;  2MQI A;  2CRH A;  3UYO A;  1B47 A;  1O4I A;  1R1P A;  4GL9 E;  1AOU F;  4U1P A;  4LUE A;  3VS7 A;  3N84 A;  1BFI A;  3PQZ A;  1O4A A;  2HDX A;  3BUO B;  3GXX A;  1M27 A;  5DC9 A;  4EIH A;  3VRN A;  2DX0 A;  1O4K A;  2XP1 A;  1Y57 A;  1O4E A;  1YVL A;  1O44 A;  2CI9 A;  3PS5 A;  2GSB A;  3MXY A;  3M7F A;  2HCK A;  1F1W A;  1CWE A;  1SHD A;  2ECD A;  2B3O A;  1O41 A;  1LUI A;  1SHA A;  1NRV A;  1KA7 A;  1BFJ A;  2IUG A;  2ETZ A;  2ROR A;  1BHH B;  2Y3A B;  1GHU A;  1BG1 A;  2CIA A;  1UUR A;  3VS3 A;  2PLD A;  3VS0 A;  2AUG A;  5I6V A;  4A4C A;  5GJI A;  1KA6 A;  1P13 A;  2EL8 A;  1JYU A;  4FBN A;  1O45 A;  3BKB A;  4OHD A;  3VS1 A;  1BMB A;  5AXI A;  3IMD A;  3WA4 A;  5HKZ A;  2QMS A;  1OO3 A;  2C0I A;  5CDW A;  3GQI B;  5DC4 A;  5BO4 A;  2K79 B;  3KFJ A;  1LKL A;  1AYD A;  1O4M A;  1O4B A;  2IUH A;  1BHH A;  1A08 A;  1FHS A;  3VRQ A;  4QSY A;  2MK2 A;  3CBL A;  2C0T A;  1NZL A;  3PLF B;  5J3X A;  2HUW A;  5DC0 B;  1D1Z A;  3BUM B;  1FU5 A;  1QCF A;  2OQ1 A;  2EU0 A;  2CBL A;  3K2M A;  2HDV A;  4D8K A;  1O4F A;  3VRY A;  2AOB A;  3BUN B;  4F59 A;  5HKY A;  2DM0 A;  2GE9 A;  2FCI A;  1BLK A;  3VS6 A;  3PSJ A;  1HCS B;  3VS2 A;  2CR4 A;  2LNW A;  1BHF A;  1SPS A;  1AOT F;  1O4G A;  4F5B A;  3CWG A;  3S8N A;  2H8H A;  1BLJ A;  5AUL A;  3QWX X;  2K7A B;  3US4 A;  1FU6 A;  1UUS A;  1LKK A;  2L6K A;  1XA6 A;  1FBV A;  3N7Y A;  1SKJ A;  1KSW A;  3VRR A;  5EG3 B;  5D0J A;  4WWQ A;  1AYB A;  1A07 A;  2FO0 A;  3OV1 A;  4TZI A;  1O4C A;  5EHR A;  1X0N A;  1A81 A;  2Y1M A;  4GWF A;  3IN8 A;  4M4Z A;  2PNA A;  2LQW A;  4JGH A;  4OHI A;  1QG1 E;  1BKL A;  1LCJ A;  1FBZ A;  4GPL B;  3MAZ A;  3GXW A;  1O46 A;  3S8L A;  1CJ1 A;  1A1A A;  2LCT A;  1LUN A;  1O4R A;  1IS0 A;  1BKM A;  4JEG A;  2C9W A;  2SRC A;  4P9V A;  1AD5 A;  1OO4 A;  2Y1N A;  3PSK A;  1HCT B;  1O42 A;  1NZV A;  4NWG A;  1K9A A;  4DGX A;  4H34 A;  1O4N A;  1H9O A;  4OHL A;  3HHM B;  1GRI A;  2JYQ A;  2C0O A;  1LUK A;  3TKZ A;  1O4H A;  2PLE A;  3OVE A;  1TCE A;  2DCR A;  1QAD A;  1O4D A;  3EAZ A;  4K11 A;  2IZV A;  1Y1U A;  4E68 A;  1D4T A;  3UF4 A;  1O4O A;  2CI8 A;  1KC2 A;  3OP0 A;  5EEL A;  3QWY A;  3IN7 A;  2OZO A;  4OHH A;  1CSZ A;  2CS0 A;  2LNX A;  2LQN A;  4K45 A;  5IBM A;  1X27 A;  4U17 A;  1YVH A;  1R1Q A;  1D4W A;  4K2R A;  1RQQ C;  3TL0 A;  1SHB A;  2MRJ A;  2YU7 A;  3N8M A;  1A1E A;  5DF6 A;  5EEQ A;  3S9K A;  1M61 A;  3PJP A;  4L1B B;  1SPR A;  1RPY A;  2DLY A;  1X6C A;  4NWF A;  1O49 A;  4OHE A;  1A09 A;  1RJA A;  1BF5 A;  1AB2 A;  1CSY A;  1WQU A;  2YSX A;  1JWO A;  4P9Z A;  1A1C A;  1LCK A;  2EKX A;  2L4K A;  1MIL A;  2KNO A;  4ROJ A;  2RVF A;  2AOA A;  1I3Z A;  3CXL A;  3NHN A;  1O43 A; 
#chains in the Genus database with same CATH topology
 1A1B A;  4F5A A;  1JYR A;  3VS5 A;  3OB2 B;  1JYQ A;  2MC1 A;  1IJR A;  1BM2 A;  1O4L A;  3PFV A;  2RMX A;  1O4P A;  2EYZ A;  3HCK A;  2SHP A;  2DLZ A;  3VRO A;  3VS4 A;  2BBU A;  4LUD A;  1AYA A;  1G83 A;  3C7I A;  3EAC A;  2HMH A;  4DGP A;  1O4J A;  1Z3K A;  3CD3 A;  2DVJ A;  3T04 A;  4XZ1 A;  4JE4 A;  1R1S A;  2H46 E;  2RSY A;  2L3T A;  3ZNI A;  2PNB A;  4EY0 A;  3OB1 B;  2EYV A;  2IUI A;  4FL2 A;  1O48 A;  3BUX B;  1F2F A;  1AYC A;  2PTK A;  1FMK A;  2VIF A;  5EHP A;  1FYR A;  1TZE E;  4XZ0 A;  2EOB A;  1LUM A;  3MXC A;  1OPL A;  1O47 A;  5GJH A;  2EO3 A;  5IBS A;  1ZFP E;  5KAZ A;  1CWD L;  5HKW A;  4A4B A;  3S8O A;  1MW4 A;  2H5K A;  3VRP A;  2ABL A;  1O4Q A;  4FL3 A;  2EO6 A;  4X6S A;  1JU5 A;  1OPK A;  2KK6 A;  4H1O A;  3VRZ A;  3HIZ B;  3BUW B;  3VGO A;  3IMJ A;  2MRK A;  1PIC A;  4K44 A;  2EYY A;  4E93 A;  2MQI A;  2CRH A;  3UYO A;  1B47 A;  1O4I A;  1R1P A;  4GL9 E;  1AOU F;  4U1P A;  4LUE A;  3VS7 A;  3N84 A;  1BFI A;  3PQZ A;  1O4A A;  2HDX A;  3BUO B;  3GXX A;  1M27 A;  5DC9 A;  4EIH A;  3VRN A;  2DX0 A;  1O4K A;  2XP1 A;  1Y57 A;  1O4E A;  1YVL A;  1O44 A;  2CI9 A;  3PS5 A;  2GSB A;  3MXY A;  3M7F A;  2HCK A;  1F1W A;  1CWE A;  1SHD A;  2ECD A;  2B3O A;  1O41 A;  1LUI A;  1SHA A;  1NRV A;  1KA7 A;  1BFJ A;  2IUG A;  2ETZ A;  2ROR A;  1BHH B;  2Y3A B;  1GHU A;  1BG1 A;  2CIA A;  1UUR A;  3VS3 A;  2PLD A;  3VS0 A;  2AUG A;  5I6V A;  4A4C A;  5GJI A;  1KA6 A;  1P13 A;  2EL8 A;  1JYU A;  4FBN A;  1O45 A;  3BKB A;  4OHD A;  3VS1 A;  1BMB A;  5AXI A;  3IMD A;  3WA4 A;  5HKZ A;  2QMS A;  1OO3 A;  2C0I A;  5CDW A;  3GQI B;  5DC4 A;  5BO4 A;  2K79 B;  3KFJ A;  1LKL A;  1AYD A;  1O4M A;  1O4B A;  2IUH A;  1BHH A;  1A08 A;  1FHS A;  3VRQ A;  4QSY A;  2MK2 A;  3CBL A;  2C0T A;  1NZL A;  3PLF B;  5J3X A;  2HUW A;  5DC0 B;  1D1Z A;  3BUM B;  1FU5 A;  1QCF A;  2OQ1 A;  2EU0 A;  2CBL A;  3K2M A;  2HDV A;  4D8K A;  1O4F A;  3VRY A;  2AOB A;  3BUN B;  4F59 A;  5HKY A;  2DM0 A;  2GE9 A;  2KGY A;  2FCI A;  1BLK A;  3VS6 A;  3PSJ A;  1HCS B;  3VS2 A;  2CR4 A;  2LNW A;  1BHF A;  1SPS A;  1AOT F;  1O4G A;  4F5B A;  3CWG A;  3S8N A;  2H8H A;  1BLJ A;  5AUL A;  3QWX X;  2K7A B;  3US4 A;  1FU6 A;  1UUS A;  1LKK A;  2L6K A;  1XA6 A;  1FBV A;  3N7Y A;  1SKJ A;  1KSW A;  3VRR A;  5EG3 B;  5D0J A;  4WWQ A;  1AYB A;  1A07 A;  2FO0 A;  3OV1 A;  4TZI A;  1O4C A;  5EHR A;  1X0N A;  1A81 A;  2Y1M A;  4GWF A;  3IN8 A;  4M4Z A;  2PNA A;  2LQW A;  4JGH A;  4OHI A;  1QG1 E;  1BKL A;  1LCJ A;  2LRA A;  1FBZ A;  4GPL B;  3MAZ A;  3GXW A;  1O46 A;  3S8L A;  1CJ1 A;  1A1A A;  2LCT A;  1LUN A;  1O4R A;  1IS0 A;  1BKM A;  4JEG A;  2C9W A;  2SRC A;  4P9V A;  1AD5 A;  1OO4 A;  2Y1N A;  3PSK A;  1HCT B;  1O42 A;  1NZV A;  4NWG A;  1K9A A;  4DGX A;  4H34 A;  1O4N A;  1H9O A;  4OHL A;  3HHM B;  1GRI A;  2JYQ A;  2C0O A;  1LUK A;  3TKZ A;  1O4H A;  2PLE A;  3OVE A;  1TCE A;  2DCR A;  1QAD A;  1O4D A;  3EAZ A;  4K11 A;  2IZV A;  1Y1U A;  4E68 A;  1D4T A;  3UF4 A;  1O4O A;  2CI8 A;  1KC2 A;  3OP0 A;  5EEL A;  3QWY A;  3IN7 A;  2OZO A;  4OHH A;  1CSZ A;  2CS0 A;  2LNX A;  2LQN A;  4K45 A;  5IBM A;  1X27 A;  4U17 A;  1YVH A;  1R1Q A;  1D4W A;  4K2R A;  1RQQ C;  3TL0 A;  1SHB A;  2MRJ A;  2YU7 A;  3N8M A;  3K2T A;  1A1E A;  5DF6 A;  3LYV A;  5EEQ A;  3S9K A;  1M61 A;  3PJP A;  4L1B B;  1SPR A;  1RPY A;  2DLY A;  1X6C A;  4NWF A;  1O49 A;  4OHE A;  1A09 A;  1RJA A;  1BF5 A;  1AB2 A;  1CSY A;  1WQU A;  2YSX A;  1JWO A;  4P9Z A;  1A1C A;  1LCK A;  2EKX A;  2L4K A;  1MIL A;  2KNO A;  4ROJ A;  2RVF A;  2AOA A;  1I3Z A;  3CXL A;  3NHN A;  1O43 A; 
#chains in the Genus database with same CATH homology
 1A1B A;  4F5A A;  1JYR A;  3VS5 A;  3OB2 B;  1JYQ A;  2MC1 A;  1IJR A;  1BM2 A;  1O4L A;  3PFV A;  2RMX A;  1O4P A;  2EYZ A;  3HCK A;  2SHP A;  2DLZ A;  3VRO A;  3VS4 A;  2BBU A;  4LUD A;  1AYA A;  1G83 A;  3C7I A;  3EAC A;  2HMH A;  4DGP A;  1O4J A;  1Z3K A;  3CD3 A;  2DVJ A;  3T04 A;  4XZ1 A;  4JE4 A;  1R1S A;  2H46 E;  2RSY A;  2L3T A;  3ZNI A;  2PNB A;  4EY0 A;  3OB1 B;  2EYV A;  2IUI A;  4FL2 A;  1O48 A;  3BUX B;  1F2F A;  1AYC A;  2PTK A;  1FMK A;  2VIF A;  5EHP A;  1FYR A;  1TZE E;  4XZ0 A;  2EOB A;  1LUM A;  3MXC A;  1OPL A;  1O47 A;  5GJH A;  2EO3 A;  5IBS A;  1ZFP E;  5KAZ A;  1CWD L;  5HKW A;  4A4B A;  3S8O A;  1MW4 A;  2H5K A;  3VRP A;  2ABL A;  1O4Q A;  4FL3 A;  2EO6 A;  4X6S A;  1JU5 A;  1OPK A;  2KK6 A;  4H1O A;  3VRZ A;  3HIZ B;  3BUW B;  3VGO A;  3IMJ A;  2MRK A;  1PIC A;  4K44 A;  2EYY A;  4E93 A;  2MQI A;  2CRH A;  3UYO A;  1B47 A;  1O4I A;  1R1P A;  4GL9 E;  1AOU F;  4U1P A;  4LUE A;  3VS7 A;  3N84 A;  1BFI A;  3PQZ A;  1O4A A;  2HDX A;  3BUO B;  3GXX A;  1M27 A;  5DC9 A;  4EIH A;  3VRN A;  2DX0 A;  1O4K A;  2XP1 A;  1Y57 A;  1O4E A;  1YVL A;  1O44 A;  2CI9 A;  3PS5 A;  2GSB A;  3MXY A;  3M7F A;  2HCK A;  1F1W A;  1CWE A;  1SHD A;  2ECD A;  2B3O A;  1O41 A;  1LUI A;  1SHA A;  1NRV A;  1KA7 A;  1BFJ A;  2IUG A;  2ETZ A;  2ROR A;  1BHH B;  2Y3A B;  1GHU A;  1BG1 A;  2CIA A;  1UUR A;  3VS3 A;  2PLD A;  3VS0 A;  2AUG A;  5I6V A;  4A4C A;  5GJI A;  1KA6 A;  1P13 A;  2EL8 A;  1JYU A;  4FBN A;  1O45 A;  3BKB A;  4OHD A;  3VS1 A;  1BMB A;  5AXI A;  3IMD A;  3WA4 A;  5HKZ A;  2QMS A;  1OO3 A;  2C0I A;  5CDW A;  3GQI B;  5DC4 A;  5BO4 A;  2K79 B;  3KFJ A;  1LKL A;  1AYD A;  1O4M A;  1O4B A;  2IUH A;  1BHH A;  1A08 A;  1FHS A;  3VRQ A;  4QSY A;  2MK2 A;  3CBL A;  2C0T A;  1NZL A;  3PLF B;  5J3X A;  2HUW A;  5DC0 B;  1D1Z A;  3BUM B;  1FU5 A;  1QCF A;  2OQ1 A;  2EU0 A;  2CBL A;  3K2M A;  2HDV A;  4D8K A;  1O4F A;  3VRY A;  2AOB A;  3BUN B;  4F59 A;  5HKY A;  2DM0 A;  2GE9 A;  2FCI A;  1BLK A;  3VS6 A;  3PSJ A;  1HCS B;  3VS2 A;  2CR4 A;  2LNW A;  1BHF A;  1SPS A;  1AOT F;  1O4G A;  4F5B A;  3CWG A;  3S8N A;  2H8H A;  1BLJ A;  5AUL A;  3QWX X;  2K7A B;  3US4 A;  1FU6 A;  1UUS A;  1LKK A;  2L6K A;  1XA6 A;  1FBV A;  3N7Y A;  1SKJ A;  1KSW A;  3VRR A;  5EG3 B;  5D0J A;  4WWQ A;  1AYB A;  1A07 A;  2FO0 A;  3OV1 A;  4TZI A;  1O4C A;  5EHR A;  1X0N A;  1A81 A;  2Y1M A;  4GWF A;  3IN8 A;  4M4Z A;  2PNA A;  2LQW A;  4JGH A;  4OHI A;  1QG1 E;  1BKL A;  1LCJ A;  1FBZ A;  4GPL B;  3MAZ A;  3GXW A;  1O46 A;  3S8L A;  1CJ1 A;  1A1A A;  2LCT A;  1LUN A;  1O4R A;  1IS0 A;  1BKM A;  4JEG A;  2C9W A;  2SRC A;  4P9V A;  1AD5 A;  1OO4 A;  2Y1N A;  3PSK A;  1HCT B;  1O42 A;  1NZV A;  4NWG A;  1K9A A;  4DGX A;  4H34 A;  1O4N A;  1H9O A;  4OHL A;  3HHM B;  1GRI A;  2JYQ A;  2C0O A;  1LUK A;  3TKZ A;  1O4H A;  2PLE A;  3OVE A;  1TCE A;  2DCR A;  1QAD A;  1O4D A;  3EAZ A;  4K11 A;  2IZV A;  1Y1U A;  4E68 A;  1D4T A;  3UF4 A;  1O4O A;  2CI8 A;  1KC2 A;  3OP0 A;  5EEL A;  3QWY A;  3IN7 A;  2OZO A;  4OHH A;  1CSZ A;  2CS0 A;  2LNX A;  2LQN A;  4K45 A;  5IBM A;  1X27 A;  4U17 A;  1YVH A;  1R1Q A;  1D4W A;  4K2R A;  1RQQ C;  3TL0 A;  1SHB A;  2MRJ A;  2YU7 A;  3N8M A;  1A1E A;  5DF6 A;  5EEQ A;  3S9K A;  1M61 A;  3PJP A;  4L1B B;  1SPR A;  1RPY A;  2DLY A;  1X6C A;  4NWF A;  1O49 A;  4OHE A;  1A09 A;  1RJA A;  1BF5 A;  1AB2 A;  1CSY A;  1WQU A;  2YSX A;  1JWO A;  4P9Z A;  1A1C A;  1LCK A;  2EKX A;  2L4K A;  1MIL A;  2KNO A;  4ROJ A;  2RVF A;  2AOA A;  1I3Z A;  3CXL A;  3NHN A;  1O43 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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