1LUKA

Nmr structure of the itk sh2 domain, pro287cis, energy minimized average structure
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
108
structure length
108
Chain Sequence
NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a proline-driven conformational switch within the Itk SH2 domain
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Tyrosine-protein kinase ITK/TSK
total genus 13
structure length 108
sequence length 108
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2002-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1lukA00
2EYZA 3GXXA 1YVHA 1SHAA 1OPKA 1O4QA 3T04A 5EEQA 2GSBA 5AXIA 3KFJA 4TZIA 1K9AA 5AULA 1SPSA 2QMSA 4X6SA 2DM0A 1BHHA 1D4WA 1BFIA 1AYBA 1A1AA 4F59A 1BF5A 3GQIB 2PTKA 2CI9A 2ETZA 2L6KA 1H9OA 2EL8A 4K44A 1CSYA 4EY0A 1O42A 1OPLA 3MAZA 1LCKA 3VS4A 5DC0B 3MXYA 2HMHA 1X27A 1JYQA 5CDWA 2H8HA 4E93A 1BM2A 3S8LA 1A81A 1M61A 3GXWA 4F5BA 1A1CA 3VS3A 1TCEA 5EHRA 1A08A 1AYCA 5HKWA 3VS5A 3PLFB 3PSJA 1KA7A 5EELA 5GJHA 1SHBA 4ROJA 1OO3A 2AOAA 2HCKA 1O49A 2ECDA 2BBUA 1QCFA 1FHSA 1Z3KA 1A07A 1IJRA 1X6CA 2AOBA 2PNBA 5IBMA 3BKBA 1AD5A 4EIHA 2RORA 1OO4A 1FU6A 1LUIA 4U17A 1BG1A 4OHEA 1SHDA 1X0NA 3PSKA 3HHMB 1KC2A 1KA6A 3VS2A 1M27A 3OB2B 5I6VA 4FL2A 3VS1A 2YSXA 1O4IA 1P13A 2EO6A 4A4CA 3CWGA 1CSZA 4JE4A 1Y1UA 1O4JA 1JU5A 3OVEA 4H1OA 1FBZA 3TL0A 2CI8A 3HIZB 2ABLA 3VS7A 2HDVA 2FO0A 1O4LA 3VRNA 2H46E 1LCJA 3S9KA 3PS5A 3BUNB 1O4KA 1LUMA 1O4OA 5EG3B 3N84A 2KNOA 3C7IA 3EAZA 1JWOA 3UYOA 1BLJA 3CD3A 1D4TA 1JYUA 2CS0A 2CBLA 1O46A 2LNXA 4M4ZA 4K11A 4QSYA 2DX0A 3VROA 4OHHA 3OP0A 1UUSA 5DF6A 4OHLA 2GE9A 4JEGA 1O4PA 2LQNA 1G83A 1QG1E 2C0IA 1MW4A 2MC1A 1AYAA 3TKZA 1BHFA 5KAZA 3K2MA 2HUWA 5DC4A 2K79B 1O4MA 2RVFA 4L1BB 1O47A 3PJPA 1A1EA 1CJ1A 1LUKA 2Y3AB 4F5AA 2EYVA 4GWFA 2RSYA 3BUMB 5D0JA 1A1BA 4H34A 3BUOB 3OV1A 4DGXA 2EO3A 4GPLB 2CR4A 1O4CA 1RPYA 1SKJA 1QADA 4P9VA 5DC9A 1BHHB 3PFVA 1CWEA 3VS0A 1R1SA 4LUEA 1BLKA 2EU0A 2DCRA 2KK6A 1O4DA 3IMJA 1HCSB 1AB2A 1R1QA 1AOUF 4U1PA 2EKXA 5BO4A 2YU7A 1RQQC 1A09A 2RMXA 3WA4A 2Y1NA 1CWDL 1B47A 5IBSA 2FCIA 4FBNA 1LKKA 1O4EA 1FYRA 2MRJA 1NZLA 5J3XA 1YVLA 1LKLA 4NWGA 2L4KA 3ZNIA 2LCTA 1UURA 1BKMA 2LQWA 4GL9E 2DLYA 3EACA 2PLEA 2IUHA 3N7YA 2HDXA 4D8KA 1GHUA 3S8OA 3PQZA 4K2RA 1JYRA 2IUGA 1TZEE 3OB1B 1O4AA 2CRHA 1FU5A 3VS6A 3VRQA 5HKZA 2L3TA 3S8NA 2K7AB 1PICA 3HCKA 4DGPA 5EHPA 5GJIA 3US4A 4XZ0A 2Y1MA 2PLDA 3VRPA 3MXCA 1FBVA 1RJAA 3CBLA 5HKYA 1O4RA 3N8MA 1BFJA 2H5KA 1D1ZA 2PNAA 1FMKA 2MRKA 1O41A 1I3ZA 2C0OA 4K45A 1LUNA 1ZFPE 1O4BA 1MILA 2MQIA 3VGOA 2EOBA 2DLZA 1KSWA 4A4BA 1AOTF 1BKLA 3NHNA 4NWFA 1SPRA 2EYYA 1O44A 4P9ZA 1O45A 2SRCA 3UF4A 3M7FA 1NRVA 1O4FA 1Y57A 3BUXB 4OHDA 2OQ1A 1O4GA 1O4NA 3CXLA 3VRYA 4FL3A 1WQUA 1O48A 3QWXX 1HCTB 1F1WA 1O4HA 4JGHA 2CIAA 2IUIA 3IMDA 1IS0A 4OHIA 1AYDA 1F2FA 2LNWA 3VRZA 2VIFA 4LUDA 3IN8A 2B3OA 2IZVA 2C9WA 2C0TA 3BUWB 3QWYA 1NZVA 4XZ1A 3VRRA 4E68A 3IN7A 2OZOA 2MK2A 1GRIA 2SHPA 4WWQA 1BMBA 2JYQA 1XA6A 2XP1A 2DVJA 2AUGA 1R1PA 1O43A
chains in the Genus database with same CATH superfamily
2EYZA 3GXXA 1YVHA 1SHAA 1OPKA 1O4QA 3T04A 5EEQA 2GSBA 5AXIA 3KFJA 4TZIA 1K9AA 5AULA 1SPSA 2QMSA 4X6SA 2DM0A 1BHHA 1D4WA 1BFIA 1AYBA 1A1AA 4F59A 1BF5A 3GQIB 2PTKA 2CI9A 2ETZA 2L6KA 1H9OA 2EL8A 4K44A 1CSYA 4EY0A 1O42A 1OPLA 3MAZA 1LCKA 3VS4A 5DC0B 3MXYA 2HMHA 1X27A 1JYQA 5CDWA 2H8HA 4E93A 1BM2A 3S8LA 1A81A 1M61A 3GXWA 4F5BA 1A1CA 3VS3A 1TCEA 5EHRA 1A08A 1AYCA 5HKWA 3VS5A 3PLFB 3PSJA 1KA7A 5EELA 5GJHA 1SHBA 4ROJA 1OO3A 2AOAA 2HCKA 1O49A 2ECDA 2BBUA 1QCFA 1FHSA 1Z3KA 1A07A 1IJRA 1X6CA 2AOBA 2PNBA 5IBMA 3BKBA 1AD5A 4EIHA 2RORA 1OO4A 1FU6A 1LUIA 4U17A 1BG1A 4OHEA 2KGYA 1SHDA 1X0NA 3PSKA 3HHMB 1KC2A 1KA6A 3VS2A 1M27A 3OB2B 5I6VA 4FL2A 3VS1A 2YSXA 1O4IA 1P13A 2EO6A 4A4CA 3CWGA 1CSZA 4JE4A 1Y1UA 1O4JA 1JU5A 3OVEA 4H1OA 1FBZA 3TL0A 2CI8A 3HIZB 2ABLA 3VS7A 2HDVA 2FO0A 1O4LA 3VRNA 2H46E 1LCJA 3S9KA 3LYVA 3PS5A 3BUNB 1O4KA 3K2TA 1LUMA 1O4OA 5EG3B 3N84A 2KNOA 3C7IA 3EAZA 1JWOA 3UYOA 1BLJA 3CD3A 1D4TA 1JYUA 2CS0A 2CBLA 1O46A 2LNXA 4M4ZA 4K11A 4QSYA 2DX0A 3VROA 4OHHA 3OP0A 1UUSA 5DF6A 4OHLA 2GE9A 4JEGA 1O4PA 2LQNA 1G83A 1QG1E 2C0IA 1MW4A 2MC1A 1AYAA 3TKZA 2LRAA 1BHFA 5KAZA 3K2MA 2HUWA 5DC4A 2K79B 1O4MA 2RVFA 4L1BB 1O47A 3PJPA 1A1EA 1CJ1A 1LUKA 2Y3AB 4F5AA 2EYVA 4GWFA 2RSYA 3BUMB 5D0JA 1A1BA 4H34A 3BUOB 3OV1A 4DGXA 2EO3A 4GPLB 2CR4A 1O4CA 1RPYA 1SKJA 1QADA 4P9VA 5DC9A 1BHHB 3PFVA 1CWEA 3VS0A 1R1SA 4LUEA 1BLKA 2EU0A 2DCRA 2KK6A 1O4DA 3IMJA 1HCSB 1AB2A 1R1QA 1AOUF 4U1PA 2EKXA 5BO4A 2YU7A 1RQQC 1A09A 2RMXA 3WA4A 2Y1NA 1CWDL 1B47A 5IBSA 2FCIA 4FBNA 1LKKA 1O4EA 1FYRA 2MRJA 1NZLA 5J3XA 1YVLA 1LKLA 4NWGA 2L4KA 3ZNIA 2LCTA 1UURA 1BKMA 2LQWA 4GL9E 2DLYA 3EACA 2PLEA 2IUHA 3N7YA 2HDXA 4D8KA 1GHUA 3S8OA 3PQZA 4K2RA 1JYRA 2IUGA 1TZEE 3OB1B 1O4AA 2CRHA 1FU5A 3VS6A 3VRQA 5HKZA 2L3TA 3S8NA 2K7AB 1PICA 3HCKA 4DGPA 5EHPA 5GJIA 3US4A 4XZ0A 2Y1MA 2PLDA 3VRPA 3MXCA 1FBVA 1RJAA 3CBLA 5HKYA 1O4RA 3N8MA 1BFJA 2H5KA 1D1ZA 2PNAA 1FMKA 2MRKA 1O41A 1I3ZA 2C0OA 4K45A 1LUNA 1ZFPE 1O4BA 1MILA 2MQIA 3VGOA 2EOBA 2DLZA 1KSWA 4A4BA 1AOTF 1BKLA 3NHNA 4NWFA 1SPRA 2EYYA 1O44A 4P9ZA 1O45A 2SRCA 3UF4A 3M7FA 1NRVA 1O4FA 1Y57A 3BUXB 4OHDA 2OQ1A 1O4GA 1O4NA 3CXLA 3VRYA 4FL3A 1WQUA 1O48A 3QWXX 1HCTB 1F1WA 1O4HA 4JGHA 2CIAA 2IUIA 3IMDA 1IS0A 4OHIA 1AYDA 1F2FA 2LNWA 3VRZA 2VIFA 4LUDA 3IN8A 2B3OA 2IZVA 2C9WA 2C0TA 3BUWB 3QWYA 1NZVA 4XZ1A 3VRRA 4E68A 3IN7A 2OZOA 2MK2A 1GRIA 2SHPA 4WWQA 1BMBA 2JYQA 1XA6A 2XP1A 2DVJA 2AUGA 1R1PA 1O43A
chains in the Genus database with same CATH topology
2EYZA 3GXXA 1YVHA 1SHAA 1OPKA 1O4QA 3T04A 5EEQA 2GSBA 5AXIA 3KFJA 4TZIA 1K9AA 5AULA 1SPSA 2QMSA 4X6SA 2DM0A 1BHHA 1D4WA 1BFIA 1AYBA 1A1AA 4F59A 1BF5A 3GQIB 2PTKA 2CI9A 2ETZA 2L6KA 1H9OA 2EL8A 4K44A 1CSYA 4EY0A 1O42A 1OPLA 3MAZA 1LCKA 3VS4A 5DC0B 3MXYA 2HMHA 1X27A 1JYQA 5CDWA 2H8HA 4E93A 1BM2A 3S8LA 1A81A 1M61A 3GXWA 4F5BA 1A1CA 3VS3A 1TCEA 5EHRA 1A08A 1AYCA 5HKWA 3VS5A 3PLFB 3PSJA 1KA7A 5EELA 5GJHA 1SHBA 4ROJA 1OO3A 2AOAA 2HCKA 1O49A 2ECDA 2BBUA 1QCFA 1FHSA 1Z3KA 1A07A 1IJRA 1X6CA 2AOBA 2PNBA 5IBMA 3BKBA 1AD5A 4EIHA 2RORA 1OO4A 1FU6A 1LUIA 4U17A 1BG1A 4OHEA 1SHDA 1X0NA 3PSKA 3HHMB 1KC2A 1KA6A 3VS2A 1M27A 3OB2B 5I6VA 4FL2A 3VS1A 2YSXA 1O4IA 1P13A 2EO6A 4A4CA 3CWGA 1CSZA 4JE4A 1Y1UA 1O4JA 1JU5A 3OVEA 4H1OA 1FBZA 3TL0A 2CI8A 3HIZB 2ABLA 3VS7A 2HDVA 2FO0A 1O4LA 3VRNA 2H46E 1LCJA 3S9KA 3PS5A 3BUNB 1O4KA 1LUMA 1O4OA 5EG3B 3N84A 2KNOA 3C7IA 3EAZA 1JWOA 3UYOA 1BLJA 3CD3A 1D4TA 1JYUA 2CS0A 2CBLA 1O46A 2LNXA 4M4ZA 4K11A 4QSYA 2DX0A 3VROA 4OHHA 3OP0A 1UUSA 5DF6A 4OHLA 2GE9A 4JEGA 1O4PA 2LQNA 1G83A 1QG1E 2C0IA 1MW4A 2MC1A 1AYAA 3TKZA 1BHFA 5KAZA 3K2MA 2HUWA 5DC4A 2K79B 1O4MA 2RVFA 4L1BB 1O47A 3PJPA 1A1EA 1CJ1A 1LUKA 2Y3AB 4F5AA 2EYVA 4GWFA 2RSYA 3BUMB 5D0JA 1A1BA 4H34A 3BUOB 3OV1A 4DGXA 2EO3A 4GPLB 2CR4A 1O4CA 1RPYA 1SKJA 1QADA 4P9VA 5DC9A 1BHHB 3PFVA 1CWEA 3VS0A 1R1SA 4LUEA 1BLKA 2EU0A 2DCRA 2KK6A 1O4DA 3IMJA 1HCSB 1AB2A 1R1QA 1AOUF 4U1PA 2EKXA 5BO4A 2YU7A 1RQQC 1A09A 2RMXA 3WA4A 2Y1NA 1CWDL 1B47A 5IBSA 2FCIA 4FBNA 1LKKA 1O4EA 1FYRA 2MRJA 1NZLA 5J3XA 1YVLA 1LKLA 4NWGA 2L4KA 3ZNIA 2LCTA 1UURA 1BKMA 2LQWA 4GL9E 2DLYA 3EACA 2PLEA 2IUHA 3N7YA 2HDXA 4D8KA 1GHUA 3S8OA 3PQZA 4K2RA 1JYRA 2IUGA 1TZEE 3OB1B 1O4AA 2CRHA 1FU5A 3VS6A 3VRQA 5HKZA 2L3TA 3S8NA 2K7AB 1PICA 3HCKA 4DGPA 5EHPA 5GJIA 3US4A 4XZ0A 2Y1MA 2PLDA 3VRPA 3MXCA 1FBVA 1RJAA 3CBLA 5HKYA 1O4RA 3N8MA 1BFJA 2H5KA 1D1ZA 2PNAA 1FMKA 2MRKA 1O41A 1I3ZA 2C0OA 4K45A 1LUNA 1ZFPE 1O4BA 1MILA 2MQIA 3VGOA 2EOBA 2DLZA 1KSWA 4A4BA 1AOTF 1BKLA 3NHNA 4NWFA 1SPRA 2EYYA 1O44A 4P9ZA 1O45A 2SRCA 3UF4A 3M7FA 1NRVA 1O4FA 1Y57A 3BUXB 4OHDA 2OQ1A 1O4GA 1O4NA 3CXLA 3VRYA 4FL3A 1WQUA 1O48A 3QWXX 1HCTB 1F1WA 1O4HA 4JGHA 2CIAA 2IUIA 3IMDA 1IS0A 4OHIA 1AYDA 1F2FA 2LNWA 3VRZA 2VIFA 4LUDA 3IN8A 2B3OA 2IZVA 2C9WA 2C0TA 3BUWB 3QWYA 1NZVA 4XZ1A 3VRRA 4E68A 3IN7A 2OZOA 2MK2A 1GRIA 2SHPA 4WWQA 1BMBA 2JYQA 1XA6A 2XP1A 2DVJA 2AUGA 1R1PA 1O43A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EYZ A;  3GXX A;  1YVH A;  1SHA A;  1OPK A;  1O4Q A;  3T04 A;  5EEQ A;  2GSB A;  5AXI A;  3KFJ A;  4TZI A;  1K9A A;  5AUL A;  1SPS A;  2QMS A;  4X6S A;  2DM0 A;  1BHH A;  1D4W A;  1BFI A;  1AYB A;  1A1A A;  4F59 A;  1BF5 A;  3GQI B;  2PTK A;  2CI9 A;  2ETZ A;  2L6K A;  1H9O A;  2EL8 A;  4K44 A;  1CSY A;  4EY0 A;  1O42 A;  1OPL A;  3MAZ A;  1LCK A;  3VS4 A;  5DC0 B;  3MXY A;  2HMH A;  1X27 A;  1JYQ A;  5CDW A;  2H8H A;  4E93 A;  1BM2 A;  3S8L A;  1A81 A;  1M61 A;  3GXW A;  4F5B A;  1A1C A;  3VS3 A;  1TCE A;  5EHR A;  1A08 A;  1AYC A;  5HKW A;  3VS5 A;  3PLF B;  3PSJ A;  1KA7 A;  5EEL A;  5GJH A;  1SHB A;  4ROJ A;  1OO3 A;  2AOA A;  2HCK A;  1O49 A;  2ECD A;  2BBU A;  1QCF A;  1FHS A;  1Z3K A;  1A07 A;  1IJR A;  1X6C A;  2AOB A;  2PNB A;  5IBM A;  3BKB A;  1AD5 A;  4EIH A;  2ROR A;  1OO4 A;  1FU6 A;  1LUI A;  4U17 A;  1BG1 A;  4OHE A;  1SHD A;  1X0N A;  3PSK A;  3HHM B;  1KC2 A;  1KA6 A;  3VS2 A;  1M27 A;  3OB2 B;  5I6V A;  4FL2 A;  3VS1 A;  2YSX A;  1O4I A;  1P13 A;  2EO6 A;  4A4C A;  3CWG A;  1CSZ A;  4JE4 A;  1Y1U A;  1O4J A;  1JU5 A;  3OVE A;  4H1O A;  1FBZ A;  3TL0 A;  2CI8 A;  3HIZ B;  2ABL A;  3VS7 A;  2HDV A;  2FO0 A;  1O4L A;  3VRN A;  2H46 E;  1LCJ A;  3S9K A;  3PS5 A;  3BUN B;  1O4K A;  1LUM A;  1O4O A;  5EG3 B;  3N84 A;  2KNO A;  3C7I A;  3EAZ A;  1JWO A;  3UYO A;  1BLJ A;  3CD3 A;  1D4T A;  1JYU A;  2CS0 A;  2CBL A;  1O46 A;  2LNX A;  4M4Z A;  4K11 A;  4QSY A;  2DX0 A;  3VRO A;  4OHH A;  3OP0 A;  1UUS A;  5DF6 A;  4OHL A;  2GE9 A;  4JEG A;  1O4P A;  2LQN A;  1G83 A;  1QG1 E;  2C0I A;  1MW4 A;  2MC1 A;  1AYA A;  3TKZ A;  1BHF A;  5KAZ A;  3K2M A;  2HUW A;  5DC4 A;  2K79 B;  1O4M A;  2RVF A;  4L1B B;  1O47 A;  3PJP A;  1A1E A;  1CJ1 A;  1LUK A;  2Y3A B;  4F5A A;  2EYV A;  4GWF A;  2RSY A;  3BUM B;  5D0J A;  1A1B A;  4H34 A;  3BUO B;  3OV1 A;  4DGX A;  2EO3 A;  4GPL B;  2CR4 A;  1O4C A;  1RPY A;  1SKJ A;  1QAD A;  4P9V A;  5DC9 A;  1BHH B;  3PFV A;  1CWE A;  3VS0 A;  1R1S A;  4LUE A;  1BLK A;  2EU0 A;  2DCR A;  2KK6 A;  1O4D A;  3IMJ A;  1HCS B;  1AB2 A;  1R1Q A;  1AOU F;  4U1P A;  2EKX A;  5BO4 A;  2YU7 A;  1RQQ C;  1A09 A;  2RMX A;  3WA4 A;  2Y1N A;  1CWD L;  1B47 A;  5IBS A;  2FCI A;  4FBN A;  1LKK A;  1O4E A;  1FYR A;  2MRJ A;  1NZL A;  5J3X A;  1YVL A;  1LKL A;  4NWG A;  2L4K A;  3ZNI A;  2LCT A;  1UUR A;  1BKM A;  2LQW A;  4GL9 E;  2DLY A;  3EAC A;  2PLE A;  2IUH A;  3N7Y A;  2HDX A;  4D8K A;  1GHU A;  3S8O A;  3PQZ A;  4K2R A;  1JYR A;  2IUG A;  1TZE E;  3OB1 B;  1O4A A;  2CRH A;  1FU5 A;  3VS6 A;  3VRQ A;  5HKZ A;  2L3T A;  3S8N A;  2K7A B;  1PIC A;  3HCK A;  4DGP A;  5EHP A;  5GJI A;  3US4 A;  4XZ0 A;  2Y1M A;  2PLD A;  3VRP A;  3MXC A;  1FBV A;  1RJA A;  3CBL A;  5HKY A;  1O4R A;  3N8M A;  1BFJ A;  2H5K A;  1D1Z A;  2PNA A;  1FMK A;  2MRK A;  1O41 A;  1I3Z A;  2C0O A;  4K45 A;  1LUN A;  1ZFP E;  1O4B A;  1MIL A;  2MQI A;  3VGO A;  2EOB A;  2DLZ A;  1KSW A;  4A4B A;  1AOT F;  1BKL A;  3NHN A;  4NWF A;  1SPR A;  2EYY A;  1O44 A;  4P9Z A;  1O45 A;  2SRC A;  3UF4 A;  3M7F A;  1NRV A;  1O4F A;  1Y57 A;  3BUX B;  4OHD A;  2OQ1 A;  1O4G A;  1O4N A;  3CXL A;  3VRY A;  4FL3 A;  1WQU A;  1O48 A;  3QWX X;  1HCT B;  1F1W A;  1O4H A;  4JGH A;  2CIA A;  2IUI A;  3IMD A;  1IS0 A;  4OHI A;  1AYD A;  1F2F A;  2LNW A;  3VRZ A;  2VIF A;  4LUD A;  3IN8 A;  2B3O A;  2IZV A;  2C9W A;  2C0T A;  3BUW B;  3QWY A;  1NZV A;  4XZ1 A;  3VRR A;  4E68 A;  3IN7 A;  2OZO A;  2MK2 A;  1GRI A;  2SHP A;  4WWQ A;  1BMB A;  2JYQ A;  1XA6 A;  2XP1 A;  2DVJ A;  2AUG A;  1R1P A;  1O43 A; 
#chains in the Genus database with same CATH topology
 2EYZ A;  3GXX A;  1YVH A;  1SHA A;  1OPK A;  1O4Q A;  3T04 A;  5EEQ A;  2GSB A;  5AXI A;  3KFJ A;  4TZI A;  1K9A A;  5AUL A;  1SPS A;  2QMS A;  4X6S A;  2DM0 A;  1BHH A;  1D4W A;  1BFI A;  1AYB A;  1A1A A;  4F59 A;  1BF5 A;  3GQI B;  2PTK A;  2CI9 A;  2ETZ A;  2L6K A;  1H9O A;  2EL8 A;  4K44 A;  1CSY A;  4EY0 A;  1O42 A;  1OPL A;  3MAZ A;  1LCK A;  3VS4 A;  5DC0 B;  3MXY A;  2HMH A;  1X27 A;  1JYQ A;  5CDW A;  2H8H A;  4E93 A;  1BM2 A;  3S8L A;  1A81 A;  1M61 A;  3GXW A;  4F5B A;  1A1C A;  3VS3 A;  1TCE A;  5EHR A;  1A08 A;  1AYC A;  5HKW A;  3VS5 A;  3PLF B;  3PSJ A;  1KA7 A;  5EEL A;  5GJH A;  1SHB A;  4ROJ A;  1OO3 A;  2AOA A;  2HCK A;  1O49 A;  2ECD A;  2BBU A;  1QCF A;  1FHS A;  1Z3K A;  1A07 A;  1IJR A;  1X6C A;  2AOB A;  2PNB A;  5IBM A;  3BKB A;  1AD5 A;  4EIH A;  2ROR A;  1OO4 A;  1FU6 A;  1LUI A;  4U17 A;  1BG1 A;  4OHE A;  2KGY A;  1SHD A;  1X0N A;  3PSK A;  3HHM B;  1KC2 A;  1KA6 A;  3VS2 A;  1M27 A;  3OB2 B;  5I6V A;  4FL2 A;  3VS1 A;  2YSX A;  1O4I A;  1P13 A;  2EO6 A;  4A4C A;  3CWG A;  1CSZ A;  4JE4 A;  1Y1U A;  1O4J A;  1JU5 A;  3OVE A;  4H1O A;  1FBZ A;  3TL0 A;  2CI8 A;  3HIZ B;  2ABL A;  3VS7 A;  2HDV A;  2FO0 A;  1O4L A;  3VRN A;  2H46 E;  1LCJ A;  3S9K A;  3LYV A;  3PS5 A;  3BUN B;  1O4K A;  3K2T A;  1LUM A;  1O4O A;  5EG3 B;  3N84 A;  2KNO A;  3C7I A;  3EAZ A;  1JWO A;  3UYO A;  1BLJ A;  3CD3 A;  1D4T A;  1JYU A;  2CS0 A;  2CBL A;  1O46 A;  2LNX A;  4M4Z A;  4K11 A;  4QSY A;  2DX0 A;  3VRO A;  4OHH A;  3OP0 A;  1UUS A;  5DF6 A;  4OHL A;  2GE9 A;  4JEG A;  1O4P A;  2LQN A;  1G83 A;  1QG1 E;  2C0I A;  1MW4 A;  2MC1 A;  1AYA A;  3TKZ A;  2LRA A;  1BHF A;  5KAZ A;  3K2M A;  2HUW A;  5DC4 A;  2K79 B;  1O4M A;  2RVF A;  4L1B B;  1O47 A;  3PJP A;  1A1E A;  1CJ1 A;  1LUK A;  2Y3A B;  4F5A A;  2EYV A;  4GWF A;  2RSY A;  3BUM B;  5D0J A;  1A1B A;  4H34 A;  3BUO B;  3OV1 A;  4DGX A;  2EO3 A;  4GPL B;  2CR4 A;  1O4C A;  1RPY A;  1SKJ A;  1QAD A;  4P9V A;  5DC9 A;  1BHH B;  3PFV A;  1CWE A;  3VS0 A;  1R1S A;  4LUE A;  1BLK A;  2EU0 A;  2DCR A;  2KK6 A;  1O4D A;  3IMJ A;  1HCS B;  1AB2 A;  1R1Q A;  1AOU F;  4U1P A;  2EKX A;  5BO4 A;  2YU7 A;  1RQQ C;  1A09 A;  2RMX A;  3WA4 A;  2Y1N A;  1CWD L;  1B47 A;  5IBS A;  2FCI A;  4FBN A;  1LKK A;  1O4E A;  1FYR A;  2MRJ A;  1NZL A;  5J3X A;  1YVL A;  1LKL A;  4NWG A;  2L4K A;  3ZNI A;  2LCT A;  1UUR A;  1BKM A;  2LQW A;  4GL9 E;  2DLY A;  3EAC A;  2PLE A;  2IUH A;  3N7Y A;  2HDX A;  4D8K A;  1GHU A;  3S8O A;  3PQZ A;  4K2R A;  1JYR A;  2IUG A;  1TZE E;  3OB1 B;  1O4A A;  2CRH A;  1FU5 A;  3VS6 A;  3VRQ A;  5HKZ A;  2L3T A;  3S8N A;  2K7A B;  1PIC A;  3HCK A;  4DGP A;  5EHP A;  5GJI A;  3US4 A;  4XZ0 A;  2Y1M A;  2PLD A;  3VRP A;  3MXC A;  1FBV A;  1RJA A;  3CBL A;  5HKY A;  1O4R A;  3N8M A;  1BFJ A;  2H5K A;  1D1Z A;  2PNA A;  1FMK A;  2MRK A;  1O41 A;  1I3Z A;  2C0O A;  4K45 A;  1LUN A;  1ZFP E;  1O4B A;  1MIL A;  2MQI A;  3VGO A;  2EOB A;  2DLZ A;  1KSW A;  4A4B A;  1AOT F;  1BKL A;  3NHN A;  4NWF A;  1SPR A;  2EYY A;  1O44 A;  4P9Z A;  1O45 A;  2SRC A;  3UF4 A;  3M7F A;  1NRV A;  1O4F A;  1Y57 A;  3BUX B;  4OHD A;  2OQ1 A;  1O4G A;  1O4N A;  3CXL A;  3VRY A;  4FL3 A;  1WQU A;  1O48 A;  3QWX X;  1HCT B;  1F1W A;  1O4H A;  4JGH A;  2CIA A;  2IUI A;  3IMD A;  1IS0 A;  4OHI A;  1AYD A;  1F2F A;  2LNW A;  3VRZ A;  2VIF A;  4LUD A;  3IN8 A;  2B3O A;  2IZV A;  2C9W A;  2C0T A;  3BUW B;  3QWY A;  1NZV A;  4XZ1 A;  3VRR A;  4E68 A;  3IN7 A;  2OZO A;  2MK2 A;  1GRI A;  2SHP A;  4WWQ A;  1BMB A;  2JYQ A;  1XA6 A;  2XP1 A;  2DVJ A;  2AUG A;  1R1P A;  1O43 A; 
#chains in the Genus database with same CATH homology
 2EYZ A;  3GXX A;  1YVH A;  1SHA A;  1OPK A;  1O4Q A;  3T04 A;  5EEQ A;  2GSB A;  5AXI A;  3KFJ A;  4TZI A;  1K9A A;  5AUL A;  1SPS A;  2QMS A;  4X6S A;  2DM0 A;  1BHH A;  1D4W A;  1BFI A;  1AYB A;  1A1A A;  4F59 A;  1BF5 A;  3GQI B;  2PTK A;  2CI9 A;  2ETZ A;  2L6K A;  1H9O A;  2EL8 A;  4K44 A;  1CSY A;  4EY0 A;  1O42 A;  1OPL A;  3MAZ A;  1LCK A;  3VS4 A;  5DC0 B;  3MXY A;  2HMH A;  1X27 A;  1JYQ A;  5CDW A;  2H8H A;  4E93 A;  1BM2 A;  3S8L A;  1A81 A;  1M61 A;  3GXW A;  4F5B A;  1A1C A;  3VS3 A;  1TCE A;  5EHR A;  1A08 A;  1AYC A;  5HKW A;  3VS5 A;  3PLF B;  3PSJ A;  1KA7 A;  5EEL A;  5GJH A;  1SHB A;  4ROJ A;  1OO3 A;  2AOA A;  2HCK A;  1O49 A;  2ECD A;  2BBU A;  1QCF A;  1FHS A;  1Z3K A;  1A07 A;  1IJR A;  1X6C A;  2AOB A;  2PNB A;  5IBM A;  3BKB A;  1AD5 A;  4EIH A;  2ROR A;  1OO4 A;  1FU6 A;  1LUI A;  4U17 A;  1BG1 A;  4OHE A;  1SHD A;  1X0N A;  3PSK A;  3HHM B;  1KC2 A;  1KA6 A;  3VS2 A;  1M27 A;  3OB2 B;  5I6V A;  4FL2 A;  3VS1 A;  2YSX A;  1O4I A;  1P13 A;  2EO6 A;  4A4C A;  3CWG A;  1CSZ A;  4JE4 A;  1Y1U A;  1O4J A;  1JU5 A;  3OVE A;  4H1O A;  1FBZ A;  3TL0 A;  2CI8 A;  3HIZ B;  2ABL A;  3VS7 A;  2HDV A;  2FO0 A;  1O4L A;  3VRN A;  2H46 E;  1LCJ A;  3S9K A;  3PS5 A;  3BUN B;  1O4K A;  1LUM A;  1O4O A;  5EG3 B;  3N84 A;  2KNO A;  3C7I A;  3EAZ A;  1JWO A;  3UYO A;  1BLJ A;  3CD3 A;  1D4T A;  1JYU A;  2CS0 A;  2CBL A;  1O46 A;  2LNX A;  4M4Z A;  4K11 A;  4QSY A;  2DX0 A;  3VRO A;  4OHH A;  3OP0 A;  1UUS A;  5DF6 A;  4OHL A;  2GE9 A;  4JEG A;  1O4P A;  2LQN A;  1G83 A;  1QG1 E;  2C0I A;  1MW4 A;  2MC1 A;  1AYA A;  3TKZ A;  1BHF A;  5KAZ A;  3K2M A;  2HUW A;  5DC4 A;  2K79 B;  1O4M A;  2RVF A;  4L1B B;  1O47 A;  3PJP A;  1A1E A;  1CJ1 A;  1LUK A;  2Y3A B;  4F5A A;  2EYV A;  4GWF A;  2RSY A;  3BUM B;  5D0J A;  1A1B A;  4H34 A;  3BUO B;  3OV1 A;  4DGX A;  2EO3 A;  4GPL B;  2CR4 A;  1O4C A;  1RPY A;  1SKJ A;  1QAD A;  4P9V A;  5DC9 A;  1BHH B;  3PFV A;  1CWE A;  3VS0 A;  1R1S A;  4LUE A;  1BLK A;  2EU0 A;  2DCR A;  2KK6 A;  1O4D A;  3IMJ A;  1HCS B;  1AB2 A;  1R1Q A;  1AOU F;  4U1P A;  2EKX A;  5BO4 A;  2YU7 A;  1RQQ C;  1A09 A;  2RMX A;  3WA4 A;  2Y1N A;  1CWD L;  1B47 A;  5IBS A;  2FCI A;  4FBN A;  1LKK A;  1O4E A;  1FYR A;  2MRJ A;  1NZL A;  5J3X A;  1YVL A;  1LKL A;  4NWG A;  2L4K A;  3ZNI A;  2LCT A;  1UUR A;  1BKM A;  2LQW A;  4GL9 E;  2DLY A;  3EAC A;  2PLE A;  2IUH A;  3N7Y A;  2HDX A;  4D8K A;  1GHU A;  3S8O A;  3PQZ A;  4K2R A;  1JYR A;  2IUG A;  1TZE E;  3OB1 B;  1O4A A;  2CRH A;  1FU5 A;  3VS6 A;  3VRQ A;  5HKZ A;  2L3T A;  3S8N A;  2K7A B;  1PIC A;  3HCK A;  4DGP A;  5EHP A;  5GJI A;  3US4 A;  4XZ0 A;  2Y1M A;  2PLD A;  3VRP A;  3MXC A;  1FBV A;  1RJA A;  3CBL A;  5HKY A;  1O4R A;  3N8M A;  1BFJ A;  2H5K A;  1D1Z A;  2PNA A;  1FMK A;  2MRK A;  1O41 A;  1I3Z A;  2C0O A;  4K45 A;  1LUN A;  1ZFP E;  1O4B A;  1MIL A;  2MQI A;  3VGO A;  2EOB A;  2DLZ A;  1KSW A;  4A4B A;  1AOT F;  1BKL A;  3NHN A;  4NWF A;  1SPR A;  2EYY A;  1O44 A;  4P9Z A;  1O45 A;  2SRC A;  3UF4 A;  3M7F A;  1NRV A;  1O4F A;  1Y57 A;  3BUX B;  4OHD A;  2OQ1 A;  1O4G A;  1O4N A;  3CXL A;  3VRY A;  4FL3 A;  1WQU A;  1O48 A;  3QWX X;  1HCT B;  1F1W A;  1O4H A;  4JGH A;  2CIA A;  2IUI A;  3IMD A;  1IS0 A;  4OHI A;  1AYD A;  1F2F A;  2LNW A;  3VRZ A;  2VIF A;  4LUD A;  3IN8 A;  2B3O A;  2IZV A;  2C9W A;  2C0T A;  3BUW B;  3QWY A;  1NZV A;  4XZ1 A;  3VRR A;  4E68 A;  3IN7 A;  2OZO A;  2MK2 A;  1GRI A;  2SHP A;  4WWQ A;  1BMB A;  2JYQ A;  1XA6 A;  2XP1 A;  2DVJ A;  2AUG A;  1R1P A;  1O43 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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