1LUKA

Nmr structure of the itk sh2 domain, pro287cis, energy minimized average structure
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
108
structure length
108
Chain Sequence
NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Mus musculus
publication title Structural characterization of a proline-driven conformational switch within the Itk SH2 domain
pubmed doi rcsb
molecule keywords Tyrosine-protein kinase ITK/TSK
total genus 13
structure length 108
sequence length 108
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2002-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1lukA00
1KA6A 1G83A 1A07A 3BUMB 4XZ0A 1O4LA 3M7FA 1UUSA 1NRVA 2AOAA 3HIZB 2IUHA 4F5AA 2MK2A 1OO4A 1O4QA 3BKBA 1UURA 3NHNA 1BLKA 5EHRA 1HCSB 1A1BA 1O44A 2DX0A 2HUWA 2EKXA 4LUDA 3US4A 1KC2A 2EO3A 1LUKA 4TZIA 1BHHA 1CJ1A 5IBMA 1BMBA 3PSKA 1MW4A 1FYRA 1O4FA 3OVEA 2VIFA 4FL3A 4F5BA 1LCKA 1JYRA 3S8NA 1CSZA 2EO6A 1O4JA 2HMHA 1O41A 2LNXA 4U1PA 1SPSA 2DVJA 4F59A 1BHFA 3CXLA 4H1OA 5AULA 1AD5A 3T04A 1NZLA 1R1SA 3CWGA 2HDXA 1AYCA 1O49A 2PTKA 4NWGA 2CBLA 1FU6A 1O4DA 2RMXA 2DLZA 3BUOB 1O47A 3QWYA 4ROJA 3GXXA 4JE4A 1O43A 3OB2B 1LUIA 2RVFA 1JWOA 1SHBA 1X6CA 2C9WA 3K2MA 2LQWA 3MAZA 3MXCA 3PSJA 1O4OA 2HDVA 4LUEA 2HCKA 1X0NA 4OHEA 1A1CA 1O4GA 4P9VA 4D8KA 2AUGA 1X27A 3HHMB 5GJIA 2FO0A 1I3ZA 1O46A 4GL9E 1D1ZA 3WA4A 1FMKA 5HKZA 3VRRA 1AB2A 1IJRA 1R1QA 1O48A 1GRIA 4K2RA 1LUMA 1B47A 1BKLA 1M27A 5EG3B 5IBSA 1YVHA 1CWDL 2C0IA 2EYYA 2LCTA 1R1PA 2IUGA 1O4RA 1FU5A 2DCRA 1QADA 3N7YA 2C0OA 2CS0A 1O4CA 1F2FA 4K45A 4FBNA 3IMDA 1GHUA 2EOBA 3IMJA 1O42A 3VS4A 3BUNB 1O4IA 2CI8A 2Y3AB 4XZ1A 1FHSA 1CWEA 2ABLA 1K9AA 3HCKA 1NZVA 3CBLA 4NWFA 1BFIA 3IN7A 1HCTB 2KNOA 1O4MA 2CIAA 1H9OA 3VS1A 2RSYA 1CSYA 2GSBA 4WWQA 5J3XA 2EU0A 2SHPA 1YVLA 1O4HA 3ZNIA 4K11A 1LKKA 2LNWA 4L1BB 1O4AA 4JEGA 5BO4A 1SPRA 2OQ1A 2IZVA 1JYUA 2PLEA 3GXWA 2PNBA 2MQIA 2GE9A 5DF6A 1F1WA 5D0JA 1PICA 1RPYA 2K7AB 3OV1A 1LCJA 1O4NA 3PFVA 1BHHB 3N84A 1XA6A 2DLYA 5DC4A 1FBZA 3VROA 1SHDA 1QG1E 3VS6A 3VS3A 4M4ZA 2EL8A 4EIHA 1RJAA 1TCEA 2Y1MA 3VS5A 2KK6A 2L6KA 1AOUF 3EACA 1BG1A 3GQIB 3IN8A 1JYQA 2RORA 4OHDA 2PNAA 1Y1UA 1BKMA 5HKYA 2LQNA 1TZEE 2L3TA 5GJHA 2IUIA 3N8MA 4FL2A 1A1AA 1AOTF 1MILA 1IS0A 3PQZA 1AYDA 1BF5A 1D4WA 3EAZA 1OPLA 5DC9A 1M61A 1FBVA 1SHAA 2CI9A 3KFJA 3PS5A 5HKWA 4EY0A 4P9ZA 3OB1B 1A81A 1O4EA 2JYQA 2CR4A 3BUWB 2YU7A 3VS2A 4E93A 3S9KA 2K79B 1OPKA 1RQQC 2MRJA 2H8HA 4OHLA 1P13A 1OO3A 3VRYA 2XP1A 2L4KA 1SKJA 2SRCA 4K44A 1LUNA 4OHIA 1KSWA 1AYBA 4QSYA 3VRZA 2EYVA 1A09A 5EELA 5EEQA 2B3OA 1WQUA 1AYAA 4A4BA 1O4KA 3CD3A 4H34A 1JU5A 2QMSA 4OHHA 5DC0B 2MC1A 2AOBA 2BBUA 5EHPA 5I6VA 3TKZA 1LKLA 2ETZA 1Z3KA 2MRKA 3VS7A 3VRQA 2PLDA 3TL0A 1BLJA 4X6SA 4GWFA 2FCIA 3QWXX 1QCFA 1O45A 5AXIA 3S8LA 2ECDA 3VRPA 2CRHA 3VGOA 1BM2A 1BFJA 3MXYA 3BUXB 2C0TA 1D4TA 3VS0A 3UYOA 1ZFPE 4U17A 1Y57A 2Y1NA 5CDWA 4JGHA 4DGXA 1A08A 1A1EA 4E68A 3UF4A 2OZOA 1KA7A 3OP0A 3S8OA 4GPLB 2YSXA 2DM0A 2H5KA 3PJPA 4A4CA 3VRNA 2H46E 4DGPA 5KAZA 3PLFB 3C7IA 2EYZA 1O4PA 1O4BA
chains in the Genus database with same CATH superfamily
1KA6A 1G83A 1A07A 3BUMB 4XZ0A 1O4LA 3M7FA 1UUSA 1NRVA 2AOAA 3HIZB 2IUHA 4F5AA 2MK2A 1OO4A 1O4QA 3BKBA 1UURA 3NHNA 1BLKA 5EHRA 1HCSB 1A1BA 1O44A 2DX0A 2HUWA 2EKXA 4LUDA 3US4A 1KC2A 2EO3A 1LUKA 4TZIA 1BHHA 1CJ1A 5IBMA 1BMBA 3PSKA 1MW4A 1FYRA 1O4FA 3OVEA 2VIFA 4FL3A 4F5BA 1LCKA 1JYRA 3S8NA 1CSZA 2EO6A 1O4JA 2HMHA 1O41A 2LNXA 4U1PA 1SPSA 2DVJA 4F59A 1BHFA 3CXLA 4H1OA 5AULA 1AD5A 3T04A 1NZLA 1R1SA 3CWGA 2HDXA 1AYCA 1O49A 2PTKA 4NWGA 2CBLA 1FU6A 1O4DA 2RMXA 2DLZA 3BUOB 1O47A 3QWYA 4ROJA 3GXXA 4JE4A 1O43A 3OB2B 1LUIA 2RVFA 1JWOA 1SHBA 1X6CA 2C9WA 3K2MA 2LQWA 3MAZA 3MXCA 3PSJA 1O4OA 2HDVA 4LUEA 2HCKA 1X0NA 4OHEA 1A1CA 1O4GA 4P9VA 4D8KA 2AUGA 1X27A 3HHMB 5GJIA 2FO0A 1I3ZA 1O46A 4GL9E 1D1ZA 3WA4A 1FMKA 5HKZA 3VRRA 1AB2A 1IJRA 1R1QA 1O48A 1GRIA 4K2RA 1LUMA 1B47A 1BKLA 1M27A 5EG3B 5IBSA 1YVHA 1CWDL 2C0IA 2EYYA 2LCTA 1R1PA 2IUGA 1O4RA 1FU5A 2DCRA 1QADA 3N7YA 2C0OA 2CS0A 1O4CA 1F2FA 4K45A 4FBNA 3IMDA 1GHUA 2EOBA 3IMJA 1O42A 3VS4A 3BUNB 2KGYA 1O4IA 2CI8A 2Y3AB 4XZ1A 1FHSA 1CWEA 2ABLA 1K9AA 3HCKA 1NZVA 3CBLA 4NWFA 1BFIA 3IN7A 1HCTB 2KNOA 1O4MA 2CIAA 1H9OA 3VS1A 2RSYA 1CSYA 2GSBA 4WWQA 5J3XA 2EU0A 2SHPA 1YVLA 1O4HA 3ZNIA 4K11A 1LKKA 2LNWA 4L1BB 1O4AA 4JEGA 5BO4A 2LRAA 1SPRA 2OQ1A 2IZVA 1JYUA 2PLEA 3GXWA 2PNBA 2MQIA 2GE9A 5DF6A 1F1WA 5D0JA 1PICA 1RPYA 2K7AB 3OV1A 1LCJA 1O4NA 3PFVA 1BHHB 3N84A 1XA6A 2DLYA 5DC4A 3K2TA 1FBZA 3VROA 1SHDA 1QG1E 3VS6A 3VS3A 4M4ZA 2EL8A 4EIHA 1RJAA 1TCEA 2Y1MA 3VS5A 2KK6A 2L6KA 1AOUF 3EACA 1BG1A 3GQIB 3IN8A 1JYQA 2RORA 4OHDA 2PNAA 1Y1UA 1BKMA 5HKYA 2LQNA 1TZEE 2L3TA 5GJHA 2IUIA 3N8MA 4FL2A 1A1AA 1AOTF 1MILA 1IS0A 3PQZA 1AYDA 1BF5A 1D4WA 3EAZA 1OPLA 5DC9A 1M61A 1FBVA 1SHAA 2CI9A 3KFJA 3PS5A 5HKWA 4EY0A 4P9ZA 3OB1B 1A81A 1O4EA 2JYQA 2CR4A 3BUWB 2YU7A 3VS2A 4E93A 3S9KA 2K79B 1OPKA 1RQQC 2MRJA 2H8HA 4OHLA 1P13A 1OO3A 3VRYA 2XP1A 2L4KA 1SKJA 2SRCA 4K44A 1LUNA 4OHIA 1KSWA 1AYBA 4QSYA 3VRZA 2EYVA 1A09A 5EELA 5EEQA 2B3OA 1WQUA 1AYAA 4A4BA 1O4KA 3CD3A 4H34A 1JU5A 2QMSA 4OHHA 5DC0B 2MC1A 2AOBA 2BBUA 5EHPA 5I6VA 3LYVA 3TKZA 1LKLA 2ETZA 1Z3KA 2MRKA 3VS7A 3VRQA 2PLDA 3TL0A 1BLJA 4X6SA 4GWFA 2FCIA 3QWXX 1QCFA 1O45A 5AXIA 3S8LA 2ECDA 3VRPA 2CRHA 3VGOA 1BM2A 1BFJA 3MXYA 3BUXB 2C0TA 1D4TA 3VS0A 3UYOA 1ZFPE 4U17A 1Y57A 2Y1NA 5CDWA 4JGHA 4DGXA 1A08A 1A1EA 4E68A 3UF4A 2OZOA 1KA7A 3OP0A 3S8OA 4GPLB 2YSXA 2DM0A 2H5KA 3PJPA 4A4CA 3VRNA 2H46E 4DGPA 5KAZA 3PLFB 3C7IA 2EYZA 1O4PA 1O4BA
chains in the Genus database with same CATH topology
1KA6A 1G83A 1A07A 3BUMB 4XZ0A 1O4LA 3M7FA 1UUSA 1NRVA 2AOAA 3HIZB 2IUHA 4F5AA 2MK2A 1OO4A 1O4QA 3BKBA 1UURA 3NHNA 1BLKA 5EHRA 1HCSB 1A1BA 1O44A 2DX0A 2HUWA 2EKXA 4LUDA 3US4A 1KC2A 2EO3A 1LUKA 4TZIA 1BHHA 1CJ1A 5IBMA 1BMBA 3PSKA 1MW4A 1FYRA 1O4FA 3OVEA 2VIFA 4FL3A 4F5BA 1LCKA 1JYRA 3S8NA 1CSZA 2EO6A 1O4JA 2HMHA 1O41A 2LNXA 4U1PA 1SPSA 2DVJA 4F59A 1BHFA 3CXLA 4H1OA 5AULA 1AD5A 3T04A 1NZLA 1R1SA 3CWGA 2HDXA 1AYCA 1O49A 2PTKA 4NWGA 2CBLA 1FU6A 1O4DA 2RMXA 2DLZA 3BUOB 1O47A 3QWYA 4ROJA 3GXXA 4JE4A 1O43A 3OB2B 1LUIA 2RVFA 1JWOA 1SHBA 1X6CA 2C9WA 3K2MA 2LQWA 3MAZA 3MXCA 3PSJA 1O4OA 2HDVA 4LUEA 2HCKA 1X0NA 4OHEA 1A1CA 1O4GA 4P9VA 4D8KA 2AUGA 1X27A 3HHMB 5GJIA 2FO0A 1I3ZA 1O46A 4GL9E 1D1ZA 3WA4A 1FMKA 5HKZA 3VRRA 1AB2A 1IJRA 1R1QA 1O48A 1GRIA 4K2RA 1LUMA 1B47A 1BKLA 1M27A 5EG3B 5IBSA 1YVHA 1CWDL 2C0IA 2EYYA 2LCTA 1R1PA 2IUGA 1O4RA 1FU5A 2DCRA 1QADA 3N7YA 2C0OA 2CS0A 1O4CA 1F2FA 4K45A 4FBNA 3IMDA 1GHUA 2EOBA 3IMJA 1O42A 3VS4A 3BUNB 1O4IA 2CI8A 2Y3AB 4XZ1A 1FHSA 1CWEA 2ABLA 1K9AA 3HCKA 1NZVA 3CBLA 4NWFA 1BFIA 3IN7A 1HCTB 2KNOA 1O4MA 2CIAA 1H9OA 3VS1A 2RSYA 1CSYA 2GSBA 4WWQA 5J3XA 2EU0A 2SHPA 1YVLA 1O4HA 3ZNIA 4K11A 1LKKA 2LNWA 4L1BB 1O4AA 4JEGA 5BO4A 1SPRA 2OQ1A 2IZVA 1JYUA 2PLEA 3GXWA 2PNBA 2MQIA 2GE9A 5DF6A 1F1WA 5D0JA 1PICA 1RPYA 2K7AB 3OV1A 1LCJA 1O4NA 3PFVA 1BHHB 3N84A 1XA6A 2DLYA 5DC4A 1FBZA 3VROA 1SHDA 1QG1E 3VS6A 3VS3A 4M4ZA 2EL8A 4EIHA 1RJAA 1TCEA 2Y1MA 3VS5A 2KK6A 2L6KA 1AOUF 3EACA 1BG1A 3GQIB 3IN8A 1JYQA 2RORA 4OHDA 2PNAA 1Y1UA 1BKMA 5HKYA 2LQNA 1TZEE 2L3TA 5GJHA 2IUIA 3N8MA 4FL2A 1A1AA 1AOTF 1MILA 1IS0A 3PQZA 1AYDA 1BF5A 1D4WA 3EAZA 1OPLA 5DC9A 1M61A 1FBVA 1SHAA 2CI9A 3KFJA 3PS5A 5HKWA 4EY0A 4P9ZA 3OB1B 1A81A 1O4EA 2JYQA 2CR4A 3BUWB 2YU7A 3VS2A 4E93A 3S9KA 2K79B 1OPKA 1RQQC 2MRJA 2H8HA 4OHLA 1P13A 1OO3A 3VRYA 2XP1A 2L4KA 1SKJA 2SRCA 4K44A 1LUNA 4OHIA 1KSWA 1AYBA 4QSYA 3VRZA 2EYVA 1A09A 5EELA 5EEQA 2B3OA 1WQUA 1AYAA 4A4BA 1O4KA 3CD3A 4H34A 1JU5A 2QMSA 4OHHA 5DC0B 2MC1A 2AOBA 2BBUA 5EHPA 5I6VA 3TKZA 1LKLA 2ETZA 1Z3KA 2MRKA 3VS7A 3VRQA 2PLDA 3TL0A 1BLJA 4X6SA 4GWFA 2FCIA 3QWXX 1QCFA 1O45A 5AXIA 3S8LA 2ECDA 3VRPA 2CRHA 3VGOA 1BM2A 1BFJA 3MXYA 3BUXB 2C0TA 1D4TA 3VS0A 3UYOA 1ZFPE 4U17A 1Y57A 2Y1NA 5CDWA 4JGHA 4DGXA 1A08A 1A1EA 4E68A 3UF4A 2OZOA 1KA7A 3OP0A 3S8OA 4GPLB 2YSXA 2DM0A 2H5KA 3PJPA 4A4CA 3VRNA 2H46E 4DGPA 5KAZA 3PLFB 3C7IA 2EYZA 1O4PA 1O4BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KA6 A;  1G83 A;  1A07 A;  3BUM B;  4XZ0 A;  1O4L A;  3M7F A;  1UUS A;  1NRV A;  2AOA A;  3HIZ B;  2IUH A;  4F5A A;  2MK2 A;  1OO4 A;  1O4Q A;  3BKB A;  1UUR A;  3NHN A;  1BLK A;  5EHR A;  1HCS B;  1A1B A;  1O44 A;  2DX0 A;  2HUW A;  2EKX A;  4LUD A;  3US4 A;  1KC2 A;  2EO3 A;  1LUK A;  4TZI A;  1BHH A;  1CJ1 A;  5IBM A;  1BMB A;  3PSK A;  1MW4 A;  1FYR A;  1O4F A;  3OVE A;  2VIF A;  4FL3 A;  4F5B A;  1LCK A;  1JYR A;  3S8N A;  1CSZ A;  2EO6 A;  1O4J A;  2HMH A;  1O41 A;  2LNX A;  4U1P A;  1SPS A;  2DVJ A;  4F59 A;  1BHF A;  3CXL A;  4H1O A;  5AUL A;  1AD5 A;  3T04 A;  1NZL A;  1R1S A;  3CWG A;  2HDX A;  1AYC A;  1O49 A;  2PTK A;  4NWG A;  2CBL A;  1FU6 A;  1O4D A;  2RMX A;  2DLZ A;  3BUO B;  1O47 A;  3QWY A;  4ROJ A;  3GXX A;  4JE4 A;  1O43 A;  3OB2 B;  1LUI A;  2RVF A;  1JWO A;  1SHB A;  1X6C A;  2C9W A;  3K2M A;  2LQW A;  3MAZ A;  3MXC A;  3PSJ A;  1O4O A;  2HDV A;  4LUE A;  2HCK A;  1X0N A;  4OHE A;  1A1C A;  1O4G A;  4P9V A;  4D8K A;  2AUG A;  1X27 A;  3HHM B;  5GJI A;  2FO0 A;  1I3Z A;  1O46 A;  4GL9 E;  1D1Z A;  3WA4 A;  1FMK A;  5HKZ A;  3VRR A;  1AB2 A;  1IJR A;  1R1Q A;  1O48 A;  1GRI A;  4K2R A;  1LUM A;  1B47 A;  1BKL A;  1M27 A;  5EG3 B;  5IBS A;  1YVH A;  1CWD L;  2C0I A;  2EYY A;  2LCT A;  1R1P A;  2IUG A;  1O4R A;  1FU5 A;  2DCR A;  1QAD A;  3N7Y A;  2C0O A;  2CS0 A;  1O4C A;  1F2F A;  4K45 A;  4FBN A;  3IMD A;  1GHU A;  2EOB A;  3IMJ A;  1O42 A;  3VS4 A;  3BUN B;  1O4I A;  2CI8 A;  2Y3A B;  4XZ1 A;  1FHS A;  1CWE A;  2ABL A;  1K9A A;  3HCK A;  1NZV A;  3CBL A;  4NWF A;  1BFI A;  3IN7 A;  1HCT B;  2KNO A;  1O4M A;  2CIA A;  1H9O A;  3VS1 A;  2RSY A;  1CSY A;  2GSB A;  4WWQ A;  5J3X A;  2EU0 A;  2SHP A;  1YVL A;  1O4H A;  3ZNI A;  4K11 A;  1LKK A;  2LNW A;  4L1B B;  1O4A A;  4JEG A;  5BO4 A;  1SPR A;  2OQ1 A;  2IZV A;  1JYU A;  2PLE A;  3GXW A;  2PNB A;  2MQI A;  2GE9 A;  5DF6 A;  1F1W A;  5D0J A;  1PIC A;  1RPY A;  2K7A B;  3OV1 A;  1LCJ A;  1O4N A;  3PFV A;  1BHH B;  3N84 A;  1XA6 A;  2DLY A;  5DC4 A;  1FBZ A;  3VRO A;  1SHD A;  1QG1 E;  3VS6 A;  3VS3 A;  4M4Z A;  2EL8 A;  4EIH A;  1RJA A;  1TCE A;  2Y1M A;  3VS5 A;  2KK6 A;  2L6K A;  1AOU F;  3EAC A;  1BG1 A;  3GQI B;  3IN8 A;  1JYQ A;  2ROR A;  4OHD A;  2PNA A;  1Y1U A;  1BKM A;  5HKY A;  2LQN A;  1TZE E;  2L3T A;  5GJH A;  2IUI A;  3N8M A;  4FL2 A;  1A1A A;  1AOT F;  1MIL A;  1IS0 A;  3PQZ A;  1AYD A;  1BF5 A;  1D4W A;  3EAZ A;  1OPL A;  5DC9 A;  1M61 A;  1FBV A;  1SHA A;  2CI9 A;  3KFJ A;  3PS5 A;  5HKW A;  4EY0 A;  4P9Z A;  3OB1 B;  1A81 A;  1O4E A;  2JYQ A;  2CR4 A;  3BUW B;  2YU7 A;  3VS2 A;  4E93 A;  3S9K A;  2K79 B;  1OPK A;  1RQQ C;  2MRJ A;  2H8H A;  4OHL A;  1P13 A;  1OO3 A;  3VRY A;  2XP1 A;  2L4K A;  1SKJ A;  2SRC A;  4K44 A;  1LUN A;  4OHI A;  1KSW A;  1AYB A;  4QSY A;  3VRZ A;  2EYV A;  1A09 A;  5EEL A;  5EEQ A;  2B3O A;  1WQU A;  1AYA A;  4A4B A;  1O4K A;  3CD3 A;  4H34 A;  1JU5 A;  2QMS A;  4OHH A;  5DC0 B;  2MC1 A;  2AOB A;  2BBU A;  5EHP A;  5I6V A;  3TKZ A;  1LKL A;  2ETZ A;  1Z3K A;  2MRK A;  3VS7 A;  3VRQ A;  2PLD A;  3TL0 A;  1BLJ A;  4X6S A;  4GWF A;  2FCI A;  3QWX X;  1QCF A;  1O45 A;  5AXI A;  3S8L A;  2ECD A;  3VRP A;  2CRH A;  3VGO A;  1BM2 A;  1BFJ A;  3MXY A;  3BUX B;  2C0T A;  1D4T A;  3VS0 A;  3UYO A;  1ZFP E;  4U17 A;  1Y57 A;  2Y1N A;  5CDW A;  4JGH A;  4DGX A;  1A08 A;  1A1E A;  4E68 A;  3UF4 A;  2OZO A;  1KA7 A;  3OP0 A;  3S8O A;  4GPL B;  2YSX A;  2DM0 A;  2H5K A;  3PJP A;  4A4C A;  3VRN A;  2H46 E;  4DGP A;  5KAZ A;  3PLF B;  3C7I A;  2EYZ A;  1O4P A;  1O4B A; 
#chains in the Genus database with same CATH topology
 1KA6 A;  1G83 A;  1A07 A;  3BUM B;  4XZ0 A;  1O4L A;  3M7F A;  1UUS A;  1NRV A;  2AOA A;  3HIZ B;  2IUH A;  4F5A A;  2MK2 A;  1OO4 A;  1O4Q A;  3BKB A;  1UUR A;  3NHN A;  1BLK A;  5EHR A;  1HCS B;  1A1B A;  1O44 A;  2DX0 A;  2HUW A;  2EKX A;  4LUD A;  3US4 A;  1KC2 A;  2EO3 A;  1LUK A;  4TZI A;  1BHH A;  1CJ1 A;  5IBM A;  1BMB A;  3PSK A;  1MW4 A;  1FYR A;  1O4F A;  3OVE A;  2VIF A;  4FL3 A;  4F5B A;  1LCK A;  1JYR A;  3S8N A;  1CSZ A;  2EO6 A;  1O4J A;  2HMH A;  1O41 A;  2LNX A;  4U1P A;  1SPS A;  2DVJ A;  4F59 A;  1BHF A;  3CXL A;  4H1O A;  5AUL A;  1AD5 A;  3T04 A;  1NZL A;  1R1S A;  3CWG A;  2HDX A;  1AYC A;  1O49 A;  2PTK A;  4NWG A;  2CBL A;  1FU6 A;  1O4D A;  2RMX A;  2DLZ A;  3BUO B;  1O47 A;  3QWY A;  4ROJ A;  3GXX A;  4JE4 A;  1O43 A;  3OB2 B;  1LUI A;  2RVF A;  1JWO A;  1SHB A;  1X6C A;  2C9W A;  3K2M A;  2LQW A;  3MAZ A;  3MXC A;  3PSJ A;  1O4O A;  2HDV A;  4LUE A;  2HCK A;  1X0N A;  4OHE A;  1A1C A;  1O4G A;  4P9V A;  4D8K A;  2AUG A;  1X27 A;  3HHM B;  5GJI A;  2FO0 A;  1I3Z A;  1O46 A;  4GL9 E;  1D1Z A;  3WA4 A;  1FMK A;  5HKZ A;  3VRR A;  1AB2 A;  1IJR A;  1R1Q A;  1O48 A;  1GRI A;  4K2R A;  1LUM A;  1B47 A;  1BKL A;  1M27 A;  5EG3 B;  5IBS A;  1YVH A;  1CWD L;  2C0I A;  2EYY A;  2LCT A;  1R1P A;  2IUG A;  1O4R A;  1FU5 A;  2DCR A;  1QAD A;  3N7Y A;  2C0O A;  2CS0 A;  1O4C A;  1F2F A;  4K45 A;  4FBN A;  3IMD A;  1GHU A;  2EOB A;  3IMJ A;  1O42 A;  3VS4 A;  3BUN B;  2KGY A;  1O4I A;  2CI8 A;  2Y3A B;  4XZ1 A;  1FHS A;  1CWE A;  2ABL A;  1K9A A;  3HCK A;  1NZV A;  3CBL A;  4NWF A;  1BFI A;  3IN7 A;  1HCT B;  2KNO A;  1O4M A;  2CIA A;  1H9O A;  3VS1 A;  2RSY A;  1CSY A;  2GSB A;  4WWQ A;  5J3X A;  2EU0 A;  2SHP A;  1YVL A;  1O4H A;  3ZNI A;  4K11 A;  1LKK A;  2LNW A;  4L1B B;  1O4A A;  4JEG A;  5BO4 A;  2LRA A;  1SPR A;  2OQ1 A;  2IZV A;  1JYU A;  2PLE A;  3GXW A;  2PNB A;  2MQI A;  2GE9 A;  5DF6 A;  1F1W A;  5D0J A;  1PIC A;  1RPY A;  2K7A B;  3OV1 A;  1LCJ A;  1O4N A;  3PFV A;  1BHH B;  3N84 A;  1XA6 A;  2DLY A;  5DC4 A;  3K2T A;  1FBZ A;  3VRO A;  1SHD A;  1QG1 E;  3VS6 A;  3VS3 A;  4M4Z A;  2EL8 A;  4EIH A;  1RJA A;  1TCE A;  2Y1M A;  3VS5 A;  2KK6 A;  2L6K A;  1AOU F;  3EAC A;  1BG1 A;  3GQI B;  3IN8 A;  1JYQ A;  2ROR A;  4OHD A;  2PNA A;  1Y1U A;  1BKM A;  5HKY A;  2LQN A;  1TZE E;  2L3T A;  5GJH A;  2IUI A;  3N8M A;  4FL2 A;  1A1A A;  1AOT F;  1MIL A;  1IS0 A;  3PQZ A;  1AYD A;  1BF5 A;  1D4W A;  3EAZ A;  1OPL A;  5DC9 A;  1M61 A;  1FBV A;  1SHA A;  2CI9 A;  3KFJ A;  3PS5 A;  5HKW A;  4EY0 A;  4P9Z A;  3OB1 B;  1A81 A;  1O4E A;  2JYQ A;  2CR4 A;  3BUW B;  2YU7 A;  3VS2 A;  4E93 A;  3S9K A;  2K79 B;  1OPK A;  1RQQ C;  2MRJ A;  2H8H A;  4OHL A;  1P13 A;  1OO3 A;  3VRY A;  2XP1 A;  2L4K A;  1SKJ A;  2SRC A;  4K44 A;  1LUN A;  4OHI A;  1KSW A;  1AYB A;  4QSY A;  3VRZ A;  2EYV A;  1A09 A;  5EEL A;  5EEQ A;  2B3O A;  1WQU A;  1AYA A;  4A4B A;  1O4K A;  3CD3 A;  4H34 A;  1JU5 A;  2QMS A;  4OHH A;  5DC0 B;  2MC1 A;  2AOB A;  2BBU A;  5EHP A;  5I6V A;  3LYV A;  3TKZ A;  1LKL A;  2ETZ A;  1Z3K A;  2MRK A;  3VS7 A;  3VRQ A;  2PLD A;  3TL0 A;  1BLJ A;  4X6S A;  4GWF A;  2FCI A;  3QWX X;  1QCF A;  1O45 A;  5AXI A;  3S8L A;  2ECD A;  3VRP A;  2CRH A;  3VGO A;  1BM2 A;  1BFJ A;  3MXY A;  3BUX B;  2C0T A;  1D4T A;  3VS0 A;  3UYO A;  1ZFP E;  4U17 A;  1Y57 A;  2Y1N A;  5CDW A;  4JGH A;  4DGX A;  1A08 A;  1A1E A;  4E68 A;  3UF4 A;  2OZO A;  1KA7 A;  3OP0 A;  3S8O A;  4GPL B;  2YSX A;  2DM0 A;  2H5K A;  3PJP A;  4A4C A;  3VRN A;  2H46 E;  4DGP A;  5KAZ A;  3PLF B;  3C7I A;  2EYZ A;  1O4P A;  1O4B A; 
#chains in the Genus database with same CATH homology
 1KA6 A;  1G83 A;  1A07 A;  3BUM B;  4XZ0 A;  1O4L A;  3M7F A;  1UUS A;  1NRV A;  2AOA A;  3HIZ B;  2IUH A;  4F5A A;  2MK2 A;  1OO4 A;  1O4Q A;  3BKB A;  1UUR A;  3NHN A;  1BLK A;  5EHR A;  1HCS B;  1A1B A;  1O44 A;  2DX0 A;  2HUW A;  2EKX A;  4LUD A;  3US4 A;  1KC2 A;  2EO3 A;  1LUK A;  4TZI A;  1BHH A;  1CJ1 A;  5IBM A;  1BMB A;  3PSK A;  1MW4 A;  1FYR A;  1O4F A;  3OVE A;  2VIF A;  4FL3 A;  4F5B A;  1LCK A;  1JYR A;  3S8N A;  1CSZ A;  2EO6 A;  1O4J A;  2HMH A;  1O41 A;  2LNX A;  4U1P A;  1SPS A;  2DVJ A;  4F59 A;  1BHF A;  3CXL A;  4H1O A;  5AUL A;  1AD5 A;  3T04 A;  1NZL A;  1R1S A;  3CWG A;  2HDX A;  1AYC A;  1O49 A;  2PTK A;  4NWG A;  2CBL A;  1FU6 A;  1O4D A;  2RMX A;  2DLZ A;  3BUO B;  1O47 A;  3QWY A;  4ROJ A;  3GXX A;  4JE4 A;  1O43 A;  3OB2 B;  1LUI A;  2RVF A;  1JWO A;  1SHB A;  1X6C A;  2C9W A;  3K2M A;  2LQW A;  3MAZ A;  3MXC A;  3PSJ A;  1O4O A;  2HDV A;  4LUE A;  2HCK A;  1X0N A;  4OHE A;  1A1C A;  1O4G A;  4P9V A;  4D8K A;  2AUG A;  1X27 A;  3HHM B;  5GJI A;  2FO0 A;  1I3Z A;  1O46 A;  4GL9 E;  1D1Z A;  3WA4 A;  1FMK A;  5HKZ A;  3VRR A;  1AB2 A;  1IJR A;  1R1Q A;  1O48 A;  1GRI A;  4K2R A;  1LUM A;  1B47 A;  1BKL A;  1M27 A;  5EG3 B;  5IBS A;  1YVH A;  1CWD L;  2C0I A;  2EYY A;  2LCT A;  1R1P A;  2IUG A;  1O4R A;  1FU5 A;  2DCR A;  1QAD A;  3N7Y A;  2C0O A;  2CS0 A;  1O4C A;  1F2F A;  4K45 A;  4FBN A;  3IMD A;  1GHU A;  2EOB A;  3IMJ A;  1O42 A;  3VS4 A;  3BUN B;  1O4I A;  2CI8 A;  2Y3A B;  4XZ1 A;  1FHS A;  1CWE A;  2ABL A;  1K9A A;  3HCK A;  1NZV A;  3CBL A;  4NWF A;  1BFI A;  3IN7 A;  1HCT B;  2KNO A;  1O4M A;  2CIA A;  1H9O A;  3VS1 A;  2RSY A;  1CSY A;  2GSB A;  4WWQ A;  5J3X A;  2EU0 A;  2SHP A;  1YVL A;  1O4H A;  3ZNI A;  4K11 A;  1LKK A;  2LNW A;  4L1B B;  1O4A A;  4JEG A;  5BO4 A;  1SPR A;  2OQ1 A;  2IZV A;  1JYU A;  2PLE A;  3GXW A;  2PNB A;  2MQI A;  2GE9 A;  5DF6 A;  1F1W A;  5D0J A;  1PIC A;  1RPY A;  2K7A B;  3OV1 A;  1LCJ A;  1O4N A;  3PFV A;  1BHH B;  3N84 A;  1XA6 A;  2DLY A;  5DC4 A;  1FBZ A;  3VRO A;  1SHD A;  1QG1 E;  3VS6 A;  3VS3 A;  4M4Z A;  2EL8 A;  4EIH A;  1RJA A;  1TCE A;  2Y1M A;  3VS5 A;  2KK6 A;  2L6K A;  1AOU F;  3EAC A;  1BG1 A;  3GQI B;  3IN8 A;  1JYQ A;  2ROR A;  4OHD A;  2PNA A;  1Y1U A;  1BKM A;  5HKY A;  2LQN A;  1TZE E;  2L3T A;  5GJH A;  2IUI A;  3N8M A;  4FL2 A;  1A1A A;  1AOT F;  1MIL A;  1IS0 A;  3PQZ A;  1AYD A;  1BF5 A;  1D4W A;  3EAZ A;  1OPL A;  5DC9 A;  1M61 A;  1FBV A;  1SHA A;  2CI9 A;  3KFJ A;  3PS5 A;  5HKW A;  4EY0 A;  4P9Z A;  3OB1 B;  1A81 A;  1O4E A;  2JYQ A;  2CR4 A;  3BUW B;  2YU7 A;  3VS2 A;  4E93 A;  3S9K A;  2K79 B;  1OPK A;  1RQQ C;  2MRJ A;  2H8H A;  4OHL A;  1P13 A;  1OO3 A;  3VRY A;  2XP1 A;  2L4K A;  1SKJ A;  2SRC A;  4K44 A;  1LUN A;  4OHI A;  1KSW A;  1AYB A;  4QSY A;  3VRZ A;  2EYV A;  1A09 A;  5EEL A;  5EEQ A;  2B3O A;  1WQU A;  1AYA A;  4A4B A;  1O4K A;  3CD3 A;  4H34 A;  1JU5 A;  2QMS A;  4OHH A;  5DC0 B;  2MC1 A;  2AOB A;  2BBU A;  5EHP A;  5I6V A;  3TKZ A;  1LKL A;  2ETZ A;  1Z3K A;  2MRK A;  3VS7 A;  3VRQ A;  2PLD A;  3TL0 A;  1BLJ A;  4X6S A;  4GWF A;  2FCI A;  3QWX X;  1QCF A;  1O45 A;  5AXI A;  3S8L A;  2ECD A;  3VRP A;  2CRH A;  3VGO A;  1BM2 A;  1BFJ A;  3MXY A;  3BUX B;  2C0T A;  1D4T A;  3VS0 A;  3UYO A;  1ZFP E;  4U17 A;  1Y57 A;  2Y1N A;  5CDW A;  4JGH A;  4DGX A;  1A08 A;  1A1E A;  4E68 A;  3UF4 A;  2OZO A;  1KA7 A;  3OP0 A;  3S8O A;  4GPL B;  2YSX A;  2DM0 A;  2H5K A;  3PJP A;  4A4C A;  3VRN A;  2H46 E;  4DGP A;  5KAZ A;  3PLF B;  3C7I A;  2EYZ A;  1O4P A;  1O4B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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