1NRVA

Crystal structure of the sh2 domain of grb10
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
105
structure length
100
Chain Sequence
IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 10
total genus 27
structure length 100
sequence length 105
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1nrvA00
2SRCA 4DGPA 1LUMA 4U1PA 1ZFPE 2H5KA 3VRRA 2RMXA 3PQZA 4OHEA 3VRNA 4D8KA 1QG1E 3S8LA 3EACA 1Y57A 3HIZB 3TL0A 2GE9A 2IUHA 1BMBA 1O4LA 2CS0A 1G83A 3S8NA 1O46A 1IS0A 1SPRA 3N84A 1O4NA 2RSYA 1RJAA 2YSXA 5HKYA 5GJHA 3S9KA 1F1WA 3OVEA 2DM0A 1A1EA 4WWQA 1FU6A 4A4BA 1O4PA 5I6VA 1CJ1A 1A1CA 2Y1MA 2MK2A 1O4QA 4EIHA 3IN8A 2MRKA 3CD3A 3CXLA 2IUGA 1OPLA 4QSYA 1QADA 1AOUF 3BUWB 3VS5A 3HCKA 1O49A 2VIFA 2ETZA 2MQIA 1O4DA 3EAZA 1O4AA 1X6CA 4JE4A 5EHRA 1MILA 2QMSA 1CWEA 3VS6A 3MXCA 1CWDL 2HDXA 1AB2A 3IMJA 1AD5A 1WQUA 3PSKA 1SKJA 3T04A 1AYDA 4DGXA 3ZNIA 5BO4A 1FBVA 2C0TA 4GL9E 5HKZA 3KFJA 3VRYA 2EYYA 5IBMA 1QCFA 1P13A 1CSZA 3TKZA 2DVJA 4F59A 1D4WA 1X27A 2XP1A 5AXIA 2CBLA 4FBNA 2ABLA 1TZEE 1O4BA 2PNBA 4GWFA 2H46E 4XZ1A 2FO0A 1JWOA 1HCSB 1RQQC 2CI8A 3UYOA 5EELA 1KA7A 4JEGA 1SPSA 4OHHA 3PLFB 1A1BA 4P9VA 1O4GA 1LCKA 2AOBA 4LUEA 1BHFA 5IBSA 1AOTF 2C0IA 1AYAA 2CI9A 4LUDA 4P9ZA 4U17A 4L1BB 1O4RA 1B47A 1LUKA 4F5AA 1JYQA 5DC4A 4GPLB 5GJIA 1O4EA 1KSWA 1RPYA 5EEQA 3VROA 4F5BA 2EYVA 5CDWA 2Y3AB 3GXXA 3HHMB 1UUSA 1CSYA 2OQ1A 5AULA 1O43A 1R1QA 1A07A 5KAZA 3CBLA 1KA6A 1R1SA 3S8OA 3OB2B 2KNOA 2DX0A 4FL3A 4A4CA 2L4KA 1LUNA 1O42A 3QWYA 1LKKA 3UF4A 2L3TA 1BKMA 1O4FA 2CR4A 1AYBA 1M61A 1O48A 2MRJA 1D4TA 2YU7A 2RORA 2AUGA 1OO3A 1MW4A 1A81A 1KC2A 3OP0A 1JYUA 1FU5A 2BBUA 1FMKA 3OB1B 4NWGA 2PTKA 1O4MA 2GSBA 2DCRA 4X6SA 3VRZA 1O4CA 2HUWA 1NZLA 1BFJA 1O4IA 1JU5A 1YVLA 1SHBA 3VS1A 3N8MA 5DF6A 2HMHA 2EL8A 2AOAA 1AYCA 2LNXA 3PFVA 1H9OA 3CWGA 2HDVA 3BUXB 4XZ0A 4EY0A 5D0JA 1O4KA 2L6KA 3VS4A 4H1OA 4E93A 4TZIA 4K2RA 3PJPA 2EO6A 3GQIB 1LCJA 2PNAA 2C9WA 1BHHB 3VS2A 3WA4A 1BLJA 1YVHA 3BUMB 3MXYA 1PICA 2DLYA 2K7AB 3PSJA 3VS0A 4E68A 1A08A 4OHIA 2JYQA 1BKLA 4OHLA 2HCKA 2LCTA 1BF5A 2EOBA 1D1ZA 2EO3A 4M4ZA 1GRIA 4FL2A 2LQNA 3MAZA 3QWXX 1O41A 1TCEA 2MC1A 4ROJA 1O45A 3BUOB 3VS3A 4H34A 1OO4A 3BUNB 3BKBA 3OV1A 3N7YA 1FYRA 1LUIA 2IUIA 2PLDA 3C7IA 2CRHA 1I3ZA 3K2MA 1BLKA 2PLEA 1O4JA 1FBZA 1UURA 1JYRA 5EHPA 1LKLA 3VRQA 5J3XA 3US4A 2RVFA 1A09A 1O4OA 2SHPA 1BM2A 2B3OA 1NZVA 3VGOA 2FCIA 4K11A 1O47A 3VRPA 1BFIA 1FHSA 2CIAA 3IN7A 3M7FA 1BHHA 3VS7A 1F2FA 2EU0A 2DLZA 1SHDA 3NHNA 4JGHA 2C0OA 1SHAA 5EG3B 2LNWA 1X0NA 2IZVA 2KK6A 5HKWA 5DC0B 1A1AA 2Y1NA 5DC9A 2K79B 1IJRA 4OHDA 1GHUA 4NWFA 1O44A 3GXWA 1Z3KA 4K45A 2LQWA 1OPKA 3IMDA 2OZOA 1NRVA 1BG1A 1O4HA 1R1PA 1XA6A 1Y1UA 4K44A 1K9AA 1M27A 2ECDA 2EKXA 2EYZA 3PS5A 2H8HA 1HCTB
chains in the Genus database with same CATH superfamily
2SRCA 4DGPA 1LUMA 4U1PA 1ZFPE 2H5KA 3VRRA 2RMXA 3PQZA 4OHEA 3VRNA 4D8KA 1QG1E 3S8LA 3EACA 1Y57A 3HIZB 3TL0A 2GE9A 2IUHA 1BMBA 1O4LA 2CS0A 1G83A 3S8NA 1O46A 1IS0A 1SPRA 3N84A 1O4NA 2RSYA 1RJAA 2YSXA 5HKYA 5GJHA 3S9KA 1F1WA 3OVEA 2DM0A 1A1EA 4WWQA 1FU6A 4A4BA 1O4PA 5I6VA 1CJ1A 1A1CA 2Y1MA 2MK2A 1O4QA 4EIHA 3IN8A 2MRKA 3CD3A 3CXLA 2IUGA 1OPLA 4QSYA 1QADA 1AOUF 3BUWB 3VS5A 3HCKA 1O49A 2VIFA 2ETZA 2MQIA 1O4DA 3EAZA 1O4AA 1X6CA 4JE4A 5EHRA 1MILA 2QMSA 1CWEA 3VS6A 3MXCA 1CWDL 2HDXA 1AB2A 3IMJA 1AD5A 1WQUA 3PSKA 1SKJA 3T04A 1AYDA 4DGXA 3ZNIA 5BO4A 1FBVA 2C0TA 4GL9E 5HKZA 3KFJA 3VRYA 2EYYA 5IBMA 1QCFA 1P13A 1CSZA 3TKZA 2DVJA 4F59A 2LRAA 1D4WA 1X27A 2XP1A 5AXIA 2CBLA 4FBNA 2ABLA 1TZEE 1O4BA 2PNBA 4GWFA 2H46E 4XZ1A 2FO0A 1JWOA 1HCSB 1RQQC 2CI8A 3UYOA 5EELA 1KA7A 4JEGA 1SPSA 4OHHA 3PLFB 1A1BA 4P9VA 1O4GA 1LCKA 2AOBA 4LUEA 1BHFA 5IBSA 1AOTF 2C0IA 1AYAA 2CI9A 4LUDA 4P9ZA 4U17A 4L1BB 1O4RA 1B47A 1LUKA 4F5AA 1JYQA 5DC4A 4GPLB 5GJIA 1O4EA 1KSWA 1RPYA 5EEQA 3VROA 4F5BA 2EYVA 5CDWA 2Y3AB 3GXXA 3HHMB 1UUSA 1CSYA 2OQ1A 5AULA 1O43A 1R1QA 1A07A 5KAZA 3CBLA 1KA6A 1R1SA 3S8OA 3OB2B 2KNOA 2DX0A 4FL3A 4A4CA 2L4KA 1LUNA 1O42A 3QWYA 1LKKA 3UF4A 2L3TA 1BKMA 1O4FA 2CR4A 1AYBA 1M61A 1O48A 2MRJA 1D4TA 2YU7A 2RORA 2AUGA 1OO3A 1MW4A 1A81A 1KC2A 3OP0A 1JYUA 1FU5A 2BBUA 1FMKA 3OB1B 4NWGA 2PTKA 1O4MA 2GSBA 2DCRA 4X6SA 3VRZA 1O4CA 2HUWA 1NZLA 1BFJA 1O4IA 1JU5A 1YVLA 1SHBA 3VS1A 3N8MA 5DF6A 2HMHA 2EL8A 2AOAA 1AYCA 2LNXA 3PFVA 1H9OA 3CWGA 2HDVA 3BUXB 4XZ0A 4EY0A 5D0JA 1O4KA 2L6KA 3VS4A 4H1OA 4E93A 2KGYA 4TZIA 4K2RA 3PJPA 2EO6A 3GQIB 1LCJA 2PNAA 2C9WA 1BHHB 3VS2A 3WA4A 1BLJA 1YVHA 3BUMB 3MXYA 1PICA 2DLYA 2K7AB 3PSJA 3VS0A 4E68A 1A08A 4OHIA 2JYQA 1BKLA 4OHLA 2HCKA 2LCTA 1BF5A 2EOBA 1D1ZA 2EO3A 4M4ZA 1GRIA 4FL2A 2LQNA 3MAZA 3QWXX 1O41A 1TCEA 2MC1A 4ROJA 1O45A 3BUOB 3VS3A 4H34A 1OO4A 3BUNB 3BKBA 3OV1A 3N7YA 1FYRA 1LUIA 2IUIA 2PLDA 3C7IA 2CRHA 1I3ZA 3K2MA 1BLKA 2PLEA 1O4JA 1FBZA 1UURA 1JYRA 5EHPA 1LKLA 3VRQA 5J3XA 3US4A 2RVFA 1A09A 1O4OA 2SHPA 1BM2A 2B3OA 1NZVA 3VGOA 2FCIA 4K11A 1O47A 3VRPA 1BFIA 1FHSA 2CIAA 3IN7A 3M7FA 1BHHA 3VS7A 1F2FA 2EU0A 2DLZA 1SHDA 3NHNA 4JGHA 2C0OA 1SHAA 3K2TA 5EG3B 2LNWA 1X0NA 2IZVA 3LYVA 2KK6A 5HKWA 5DC0B 1A1AA 2Y1NA 5DC9A 2K79B 1IJRA 4OHDA 1GHUA 4NWFA 1O44A 3GXWA 1Z3KA 4K45A 2LQWA 1OPKA 3IMDA 2OZOA 1NRVA 1BG1A 1O4HA 1R1PA 1XA6A 1Y1UA 4K44A 1K9AA 1M27A 2ECDA 2EKXA 2EYZA 3PS5A 2H8HA 1HCTB
chains in the Genus database with same CATH topology
2SRCA 4DGPA 1LUMA 4U1PA 1ZFPE 2H5KA 3VRRA 2RMXA 3PQZA 4OHEA 3VRNA 4D8KA 1QG1E 3S8LA 3EACA 1Y57A 3HIZB 3TL0A 2GE9A 2IUHA 1BMBA 1O4LA 2CS0A 1G83A 3S8NA 1O46A 1IS0A 1SPRA 3N84A 1O4NA 2RSYA 1RJAA 2YSXA 5HKYA 5GJHA 3S9KA 1F1WA 3OVEA 2DM0A 1A1EA 4WWQA 1FU6A 4A4BA 1O4PA 5I6VA 1CJ1A 1A1CA 2Y1MA 2MK2A 1O4QA 4EIHA 3IN8A 2MRKA 3CD3A 3CXLA 2IUGA 1OPLA 4QSYA 1QADA 1AOUF 3BUWB 3VS5A 3HCKA 1O49A 2VIFA 2ETZA 2MQIA 1O4DA 3EAZA 1O4AA 1X6CA 4JE4A 5EHRA 1MILA 2QMSA 1CWEA 3VS6A 3MXCA 1CWDL 2HDXA 1AB2A 3IMJA 1AD5A 1WQUA 3PSKA 1SKJA 3T04A 1AYDA 4DGXA 3ZNIA 5BO4A 1FBVA 2C0TA 4GL9E 5HKZA 3KFJA 3VRYA 2EYYA 5IBMA 1QCFA 1P13A 1CSZA 3TKZA 2DVJA 4F59A 1D4WA 1X27A 2XP1A 5AXIA 2CBLA 4FBNA 2ABLA 1TZEE 1O4BA 2PNBA 4GWFA 2H46E 4XZ1A 2FO0A 1JWOA 1HCSB 1RQQC 2CI8A 3UYOA 5EELA 1KA7A 4JEGA 1SPSA 4OHHA 3PLFB 1A1BA 4P9VA 1O4GA 1LCKA 2AOBA 4LUEA 1BHFA 5IBSA 1AOTF 2C0IA 1AYAA 2CI9A 4LUDA 4P9ZA 4U17A 4L1BB 1O4RA 1B47A 1LUKA 4F5AA 1JYQA 5DC4A 4GPLB 5GJIA 1O4EA 1KSWA 1RPYA 5EEQA 3VROA 4F5BA 2EYVA 5CDWA 2Y3AB 3GXXA 3HHMB 1UUSA 1CSYA 2OQ1A 5AULA 1O43A 1R1QA 1A07A 5KAZA 3CBLA 1KA6A 1R1SA 3S8OA 3OB2B 2KNOA 2DX0A 4FL3A 4A4CA 2L4KA 1LUNA 1O42A 3QWYA 1LKKA 3UF4A 2L3TA 1BKMA 1O4FA 2CR4A 1AYBA 1M61A 1O48A 2MRJA 1D4TA 2YU7A 2RORA 2AUGA 1OO3A 1MW4A 1A81A 1KC2A 3OP0A 1JYUA 1FU5A 2BBUA 1FMKA 3OB1B 4NWGA 2PTKA 1O4MA 2GSBA 2DCRA 4X6SA 3VRZA 1O4CA 2HUWA 1NZLA 1BFJA 1O4IA 1JU5A 1YVLA 1SHBA 3VS1A 3N8MA 5DF6A 2HMHA 2EL8A 2AOAA 1AYCA 2LNXA 3PFVA 1H9OA 3CWGA 2HDVA 3BUXB 4XZ0A 4EY0A 5D0JA 1O4KA 2L6KA 3VS4A 4H1OA 4E93A 4TZIA 4K2RA 3PJPA 2EO6A 3GQIB 1LCJA 2PNAA 2C9WA 1BHHB 3VS2A 3WA4A 1BLJA 1YVHA 3BUMB 3MXYA 1PICA 2DLYA 2K7AB 3PSJA 3VS0A 4E68A 1A08A 4OHIA 2JYQA 1BKLA 4OHLA 2HCKA 2LCTA 1BF5A 2EOBA 1D1ZA 2EO3A 4M4ZA 1GRIA 4FL2A 2LQNA 3MAZA 3QWXX 1O41A 1TCEA 2MC1A 4ROJA 1O45A 3BUOB 3VS3A 4H34A 1OO4A 3BUNB 3BKBA 3OV1A 3N7YA 1FYRA 1LUIA 2IUIA 2PLDA 3C7IA 2CRHA 1I3ZA 3K2MA 1BLKA 2PLEA 1O4JA 1FBZA 1UURA 1JYRA 5EHPA 1LKLA 3VRQA 5J3XA 3US4A 2RVFA 1A09A 1O4OA 2SHPA 1BM2A 2B3OA 1NZVA 3VGOA 2FCIA 4K11A 1O47A 3VRPA 1BFIA 1FHSA 2CIAA 3IN7A 3M7FA 1BHHA 3VS7A 1F2FA 2EU0A 2DLZA 1SHDA 3NHNA 4JGHA 2C0OA 1SHAA 5EG3B 2LNWA 1X0NA 2IZVA 2KK6A 5HKWA 5DC0B 1A1AA 2Y1NA 5DC9A 2K79B 1IJRA 4OHDA 1GHUA 4NWFA 1O44A 3GXWA 1Z3KA 4K45A 2LQWA 1OPKA 3IMDA 2OZOA 1NRVA 1BG1A 1O4HA 1R1PA 1XA6A 1Y1UA 4K44A 1K9AA 1M27A 2ECDA 2EKXA 2EYZA 3PS5A 2H8HA 1HCTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2SRC A;  4DGP A;  1LUM A;  4U1P A;  1ZFP E;  2H5K A;  3VRR A;  2RMX A;  3PQZ A;  4OHE A;  3VRN A;  4D8K A;  1QG1 E;  3S8L A;  3EAC A;  1Y57 A;  3HIZ B;  3TL0 A;  2GE9 A;  2IUH A;  1BMB A;  1O4L A;  2CS0 A;  1G83 A;  3S8N A;  1O46 A;  1IS0 A;  1SPR A;  3N84 A;  1O4N A;  2RSY A;  1RJA A;  2YSX A;  5HKY A;  5GJH A;  3S9K A;  1F1W A;  3OVE A;  2DM0 A;  1A1E A;  4WWQ A;  1FU6 A;  4A4B A;  1O4P A;  5I6V A;  1CJ1 A;  1A1C A;  2Y1M A;  2MK2 A;  1O4Q A;  4EIH A;  3IN8 A;  2MRK A;  3CD3 A;  3CXL A;  2IUG A;  1OPL A;  4QSY A;  1QAD A;  1AOU F;  3BUW B;  3VS5 A;  3HCK A;  1O49 A;  2VIF A;  2ETZ A;  2MQI A;  1O4D A;  3EAZ A;  1O4A A;  1X6C A;  4JE4 A;  5EHR A;  1MIL A;  2QMS A;  1CWE A;  3VS6 A;  3MXC A;  1CWD L;  2HDX A;  1AB2 A;  3IMJ A;  1AD5 A;  1WQU A;  3PSK A;  1SKJ A;  3T04 A;  1AYD A;  4DGX A;  3ZNI A;  5BO4 A;  1FBV A;  2C0T A;  4GL9 E;  5HKZ A;  3KFJ A;  3VRY A;  2EYY A;  5IBM A;  1QCF A;  1P13 A;  1CSZ A;  3TKZ A;  2DVJ A;  4F59 A;  1D4W A;  1X27 A;  2XP1 A;  5AXI A;  2CBL A;  4FBN A;  2ABL A;  1TZE E;  1O4B A;  2PNB A;  4GWF A;  2H46 E;  4XZ1 A;  2FO0 A;  1JWO A;  1HCS B;  1RQQ C;  2CI8 A;  3UYO A;  5EEL A;  1KA7 A;  4JEG A;  1SPS A;  4OHH A;  3PLF B;  1A1B A;  4P9V A;  1O4G A;  1LCK A;  2AOB A;  4LUE A;  1BHF A;  5IBS A;  1AOT F;  2C0I A;  1AYA A;  2CI9 A;  4LUD A;  4P9Z A;  4U17 A;  4L1B B;  1O4R A;  1B47 A;  1LUK A;  4F5A A;  1JYQ A;  5DC4 A;  4GPL B;  5GJI A;  1O4E A;  1KSW A;  1RPY A;  5EEQ A;  3VRO A;  4F5B A;  2EYV A;  5CDW A;  2Y3A B;  3GXX A;  3HHM B;  1UUS A;  1CSY A;  2OQ1 A;  5AUL A;  1O43 A;  1R1Q A;  1A07 A;  5KAZ A;  3CBL A;  1KA6 A;  1R1S A;  3S8O A;  3OB2 B;  2KNO A;  2DX0 A;  4FL3 A;  4A4C A;  2L4K A;  1LUN A;  1O42 A;  3QWY A;  1LKK A;  3UF4 A;  2L3T A;  1BKM A;  1O4F A;  2CR4 A;  1AYB A;  1M61 A;  1O48 A;  2MRJ A;  1D4T A;  2YU7 A;  2ROR A;  2AUG A;  1OO3 A;  1MW4 A;  1A81 A;  1KC2 A;  3OP0 A;  1JYU A;  1FU5 A;  2BBU A;  1FMK A;  3OB1 B;  4NWG A;  2PTK A;  1O4M A;  2GSB A;  2DCR A;  4X6S A;  3VRZ A;  1O4C A;  2HUW A;  1NZL A;  1BFJ A;  1O4I A;  1JU5 A;  1YVL A;  1SHB A;  3VS1 A;  3N8M A;  5DF6 A;  2HMH A;  2EL8 A;  2AOA A;  1AYC A;  2LNX A;  3PFV A;  1H9O A;  3CWG A;  2HDV A;  3BUX B;  4XZ0 A;  4EY0 A;  5D0J A;  1O4K A;  2L6K A;  3VS4 A;  4H1O A;  4E93 A;  4TZI A;  4K2R A;  3PJP A;  2EO6 A;  3GQI B;  1LCJ A;  2PNA A;  2C9W A;  1BHH B;  3VS2 A;  3WA4 A;  1BLJ A;  1YVH A;  3BUM B;  3MXY A;  1PIC A;  2DLY A;  2K7A B;  3PSJ A;  3VS0 A;  4E68 A;  1A08 A;  4OHI A;  2JYQ A;  1BKL A;  4OHL A;  2HCK A;  2LCT A;  1BF5 A;  2EOB A;  1D1Z A;  2EO3 A;  4M4Z A;  1GRI A;  4FL2 A;  2LQN A;  3MAZ A;  3QWX X;  1O41 A;  1TCE A;  2MC1 A;  4ROJ A;  1O45 A;  3BUO B;  3VS3 A;  4H34 A;  1OO4 A;  3BUN B;  3BKB A;  3OV1 A;  3N7Y A;  1FYR A;  1LUI A;  2IUI A;  2PLD A;  3C7I A;  2CRH A;  1I3Z A;  3K2M A;  1BLK A;  2PLE A;  1O4J A;  1FBZ A;  1UUR A;  1JYR A;  5EHP A;  1LKL A;  3VRQ A;  5J3X A;  3US4 A;  2RVF A;  1A09 A;  1O4O A;  2SHP A;  1BM2 A;  2B3O A;  1NZV A;  3VGO A;  2FCI A;  4K11 A;  1O47 A;  3VRP A;  1BFI A;  1FHS A;  2CIA A;  3IN7 A;  3M7F A;  1BHH A;  3VS7 A;  1F2F A;  2EU0 A;  2DLZ A;  1SHD A;  3NHN A;  4JGH A;  2C0O A;  1SHA A;  5EG3 B;  2LNW A;  1X0N A;  2IZV A;  2KK6 A;  5HKW A;  5DC0 B;  1A1A A;  2Y1N A;  5DC9 A;  2K79 B;  1IJR A;  4OHD A;  1GHU A;  4NWF A;  1O44 A;  3GXW A;  1Z3K A;  4K45 A;  2LQW A;  1OPK A;  3IMD A;  2OZO A;  1NRV A;  1BG1 A;  1O4H A;  1R1P A;  1XA6 A;  1Y1U A;  4K44 A;  1K9A A;  1M27 A;  2ECD A;  2EKX A;  2EYZ A;  3PS5 A;  2H8H A;  1HCT B; 
#chains in the Genus database with same CATH topology
 2SRC A;  4DGP A;  1LUM A;  4U1P A;  1ZFP E;  2H5K A;  3VRR A;  2RMX A;  3PQZ A;  4OHE A;  3VRN A;  4D8K A;  1QG1 E;  3S8L A;  3EAC A;  1Y57 A;  3HIZ B;  3TL0 A;  2GE9 A;  2IUH A;  1BMB A;  1O4L A;  2CS0 A;  1G83 A;  3S8N A;  1O46 A;  1IS0 A;  1SPR A;  3N84 A;  1O4N A;  2RSY A;  1RJA A;  2YSX A;  5HKY A;  5GJH A;  3S9K A;  1F1W A;  3OVE A;  2DM0 A;  1A1E A;  4WWQ A;  1FU6 A;  4A4B A;  1O4P A;  5I6V A;  1CJ1 A;  1A1C A;  2Y1M A;  2MK2 A;  1O4Q A;  4EIH A;  3IN8 A;  2MRK A;  3CD3 A;  3CXL A;  2IUG A;  1OPL A;  4QSY A;  1QAD A;  1AOU F;  3BUW B;  3VS5 A;  3HCK A;  1O49 A;  2VIF A;  2ETZ A;  2MQI A;  1O4D A;  3EAZ A;  1O4A A;  1X6C A;  4JE4 A;  5EHR A;  1MIL A;  2QMS A;  1CWE A;  3VS6 A;  3MXC A;  1CWD L;  2HDX A;  1AB2 A;  3IMJ A;  1AD5 A;  1WQU A;  3PSK A;  1SKJ A;  3T04 A;  1AYD A;  4DGX A;  3ZNI A;  5BO4 A;  1FBV A;  2C0T A;  4GL9 E;  5HKZ A;  3KFJ A;  3VRY A;  2EYY A;  5IBM A;  1QCF A;  1P13 A;  1CSZ A;  3TKZ A;  2DVJ A;  4F59 A;  2LRA A;  1D4W A;  1X27 A;  2XP1 A;  5AXI A;  2CBL A;  4FBN A;  2ABL A;  1TZE E;  1O4B A;  2PNB A;  4GWF A;  2H46 E;  4XZ1 A;  2FO0 A;  1JWO A;  1HCS B;  1RQQ C;  2CI8 A;  3UYO A;  5EEL A;  1KA7 A;  4JEG A;  1SPS A;  4OHH A;  3PLF B;  1A1B A;  4P9V A;  1O4G A;  1LCK A;  2AOB A;  4LUE A;  1BHF A;  5IBS A;  1AOT F;  2C0I A;  1AYA A;  2CI9 A;  4LUD A;  4P9Z A;  4U17 A;  4L1B B;  1O4R A;  1B47 A;  1LUK A;  4F5A A;  1JYQ A;  5DC4 A;  4GPL B;  5GJI A;  1O4E A;  1KSW A;  1RPY A;  5EEQ A;  3VRO A;  4F5B A;  2EYV A;  5CDW A;  2Y3A B;  3GXX A;  3HHM B;  1UUS A;  1CSY A;  2OQ1 A;  5AUL A;  1O43 A;  1R1Q A;  1A07 A;  5KAZ A;  3CBL A;  1KA6 A;  1R1S A;  3S8O A;  3OB2 B;  2KNO A;  2DX0 A;  4FL3 A;  4A4C A;  2L4K A;  1LUN A;  1O42 A;  3QWY A;  1LKK A;  3UF4 A;  2L3T A;  1BKM A;  1O4F A;  2CR4 A;  1AYB A;  1M61 A;  1O48 A;  2MRJ A;  1D4T A;  2YU7 A;  2ROR A;  2AUG A;  1OO3 A;  1MW4 A;  1A81 A;  1KC2 A;  3OP0 A;  1JYU A;  1FU5 A;  2BBU A;  1FMK A;  3OB1 B;  4NWG A;  2PTK A;  1O4M A;  2GSB A;  2DCR A;  4X6S A;  3VRZ A;  1O4C A;  2HUW A;  1NZL A;  1BFJ A;  1O4I A;  1JU5 A;  1YVL A;  1SHB A;  3VS1 A;  3N8M A;  5DF6 A;  2HMH A;  2EL8 A;  2AOA A;  1AYC A;  2LNX A;  3PFV A;  1H9O A;  3CWG A;  2HDV A;  3BUX B;  4XZ0 A;  4EY0 A;  5D0J A;  1O4K A;  2L6K A;  3VS4 A;  4H1O A;  4E93 A;  2KGY A;  4TZI A;  4K2R A;  3PJP A;  2EO6 A;  3GQI B;  1LCJ A;  2PNA A;  2C9W A;  1BHH B;  3VS2 A;  3WA4 A;  1BLJ A;  1YVH A;  3BUM B;  3MXY A;  1PIC A;  2DLY A;  2K7A B;  3PSJ A;  3VS0 A;  4E68 A;  1A08 A;  4OHI A;  2JYQ A;  1BKL A;  4OHL A;  2HCK A;  2LCT A;  1BF5 A;  2EOB A;  1D1Z A;  2EO3 A;  4M4Z A;  1GRI A;  4FL2 A;  2LQN A;  3MAZ A;  3QWX X;  1O41 A;  1TCE A;  2MC1 A;  4ROJ A;  1O45 A;  3BUO B;  3VS3 A;  4H34 A;  1OO4 A;  3BUN B;  3BKB A;  3OV1 A;  3N7Y A;  1FYR A;  1LUI A;  2IUI A;  2PLD A;  3C7I A;  2CRH A;  1I3Z A;  3K2M A;  1BLK A;  2PLE A;  1O4J A;  1FBZ A;  1UUR A;  1JYR A;  5EHP A;  1LKL A;  3VRQ A;  5J3X A;  3US4 A;  2RVF A;  1A09 A;  1O4O A;  2SHP A;  1BM2 A;  2B3O A;  1NZV A;  3VGO A;  2FCI A;  4K11 A;  1O47 A;  3VRP A;  1BFI A;  1FHS A;  2CIA A;  3IN7 A;  3M7F A;  1BHH A;  3VS7 A;  1F2F A;  2EU0 A;  2DLZ A;  1SHD A;  3NHN A;  4JGH A;  2C0O A;  1SHA A;  3K2T A;  5EG3 B;  2LNW A;  1X0N A;  2IZV A;  3LYV A;  2KK6 A;  5HKW A;  5DC0 B;  1A1A A;  2Y1N A;  5DC9 A;  2K79 B;  1IJR A;  4OHD A;  1GHU A;  4NWF A;  1O44 A;  3GXW A;  1Z3K A;  4K45 A;  2LQW A;  1OPK A;  3IMD A;  2OZO A;  1NRV A;  1BG1 A;  1O4H A;  1R1P A;  1XA6 A;  1Y1U A;  4K44 A;  1K9A A;  1M27 A;  2ECD A;  2EKX A;  2EYZ A;  3PS5 A;  2H8H A;  1HCT B; 
#chains in the Genus database with same CATH homology
 2SRC A;  4DGP A;  1LUM A;  4U1P A;  1ZFP E;  2H5K A;  3VRR A;  2RMX A;  3PQZ A;  4OHE A;  3VRN A;  4D8K A;  1QG1 E;  3S8L A;  3EAC A;  1Y57 A;  3HIZ B;  3TL0 A;  2GE9 A;  2IUH A;  1BMB A;  1O4L A;  2CS0 A;  1G83 A;  3S8N A;  1O46 A;  1IS0 A;  1SPR A;  3N84 A;  1O4N A;  2RSY A;  1RJA A;  2YSX A;  5HKY A;  5GJH A;  3S9K A;  1F1W A;  3OVE A;  2DM0 A;  1A1E A;  4WWQ A;  1FU6 A;  4A4B A;  1O4P A;  5I6V A;  1CJ1 A;  1A1C A;  2Y1M A;  2MK2 A;  1O4Q A;  4EIH A;  3IN8 A;  2MRK A;  3CD3 A;  3CXL A;  2IUG A;  1OPL A;  4QSY A;  1QAD A;  1AOU F;  3BUW B;  3VS5 A;  3HCK A;  1O49 A;  2VIF A;  2ETZ A;  2MQI A;  1O4D A;  3EAZ A;  1O4A A;  1X6C A;  4JE4 A;  5EHR A;  1MIL A;  2QMS A;  1CWE A;  3VS6 A;  3MXC A;  1CWD L;  2HDX A;  1AB2 A;  3IMJ A;  1AD5 A;  1WQU A;  3PSK A;  1SKJ A;  3T04 A;  1AYD A;  4DGX A;  3ZNI A;  5BO4 A;  1FBV A;  2C0T A;  4GL9 E;  5HKZ A;  3KFJ A;  3VRY A;  2EYY A;  5IBM A;  1QCF A;  1P13 A;  1CSZ A;  3TKZ A;  2DVJ A;  4F59 A;  1D4W A;  1X27 A;  2XP1 A;  5AXI A;  2CBL A;  4FBN A;  2ABL A;  1TZE E;  1O4B A;  2PNB A;  4GWF A;  2H46 E;  4XZ1 A;  2FO0 A;  1JWO A;  1HCS B;  1RQQ C;  2CI8 A;  3UYO A;  5EEL A;  1KA7 A;  4JEG A;  1SPS A;  4OHH A;  3PLF B;  1A1B A;  4P9V A;  1O4G A;  1LCK A;  2AOB A;  4LUE A;  1BHF A;  5IBS A;  1AOT F;  2C0I A;  1AYA A;  2CI9 A;  4LUD A;  4P9Z A;  4U17 A;  4L1B B;  1O4R A;  1B47 A;  1LUK A;  4F5A A;  1JYQ A;  5DC4 A;  4GPL B;  5GJI A;  1O4E A;  1KSW A;  1RPY A;  5EEQ A;  3VRO A;  4F5B A;  2EYV A;  5CDW A;  2Y3A B;  3GXX A;  3HHM B;  1UUS A;  1CSY A;  2OQ1 A;  5AUL A;  1O43 A;  1R1Q A;  1A07 A;  5KAZ A;  3CBL A;  1KA6 A;  1R1S A;  3S8O A;  3OB2 B;  2KNO A;  2DX0 A;  4FL3 A;  4A4C A;  2L4K A;  1LUN A;  1O42 A;  3QWY A;  1LKK A;  3UF4 A;  2L3T A;  1BKM A;  1O4F A;  2CR4 A;  1AYB A;  1M61 A;  1O48 A;  2MRJ A;  1D4T A;  2YU7 A;  2ROR A;  2AUG A;  1OO3 A;  1MW4 A;  1A81 A;  1KC2 A;  3OP0 A;  1JYU A;  1FU5 A;  2BBU A;  1FMK A;  3OB1 B;  4NWG A;  2PTK A;  1O4M A;  2GSB A;  2DCR A;  4X6S A;  3VRZ A;  1O4C A;  2HUW A;  1NZL A;  1BFJ A;  1O4I A;  1JU5 A;  1YVL A;  1SHB A;  3VS1 A;  3N8M A;  5DF6 A;  2HMH A;  2EL8 A;  2AOA A;  1AYC A;  2LNX A;  3PFV A;  1H9O A;  3CWG A;  2HDV A;  3BUX B;  4XZ0 A;  4EY0 A;  5D0J A;  1O4K A;  2L6K A;  3VS4 A;  4H1O A;  4E93 A;  4TZI A;  4K2R A;  3PJP A;  2EO6 A;  3GQI B;  1LCJ A;  2PNA A;  2C9W A;  1BHH B;  3VS2 A;  3WA4 A;  1BLJ A;  1YVH A;  3BUM B;  3MXY A;  1PIC A;  2DLY A;  2K7A B;  3PSJ A;  3VS0 A;  4E68 A;  1A08 A;  4OHI A;  2JYQ A;  1BKL A;  4OHL A;  2HCK A;  2LCT A;  1BF5 A;  2EOB A;  1D1Z A;  2EO3 A;  4M4Z A;  1GRI A;  4FL2 A;  2LQN A;  3MAZ A;  3QWX X;  1O41 A;  1TCE A;  2MC1 A;  4ROJ A;  1O45 A;  3BUO B;  3VS3 A;  4H34 A;  1OO4 A;  3BUN B;  3BKB A;  3OV1 A;  3N7Y A;  1FYR A;  1LUI A;  2IUI A;  2PLD A;  3C7I A;  2CRH A;  1I3Z A;  3K2M A;  1BLK A;  2PLE A;  1O4J A;  1FBZ A;  1UUR A;  1JYR A;  5EHP A;  1LKL A;  3VRQ A;  5J3X A;  3US4 A;  2RVF A;  1A09 A;  1O4O A;  2SHP A;  1BM2 A;  2B3O A;  1NZV A;  3VGO A;  2FCI A;  4K11 A;  1O47 A;  3VRP A;  1BFI A;  1FHS A;  2CIA A;  3IN7 A;  3M7F A;  1BHH A;  3VS7 A;  1F2F A;  2EU0 A;  2DLZ A;  1SHD A;  3NHN A;  4JGH A;  2C0O A;  1SHA A;  5EG3 B;  2LNW A;  1X0N A;  2IZV A;  2KK6 A;  5HKW A;  5DC0 B;  1A1A A;  2Y1N A;  5DC9 A;  2K79 B;  1IJR A;  4OHD A;  1GHU A;  4NWF A;  1O44 A;  3GXW A;  1Z3K A;  4K45 A;  2LQW A;  1OPK A;  3IMD A;  2OZO A;  1NRV A;  1BG1 A;  1O4H A;  1R1P A;  1XA6 A;  1Y1U A;  4K44 A;  1K9A A;  1M27 A;  2ECD A;  2EKX A;  2EYZ A;  3PS5 A;  2H8H A;  1HCT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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