1O49A

Crystal structure of sh2 in complex with ru85493.
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 24
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o49A00
5DF6A 1R1SA 3BKBA 2KNOA 1KA7A 3VRPA 2CRHA 4K44A 1UURA 3CXLA 1O4OA 1SHDA 2DLZA 2DVJA 2PNBA 1K9AA 3VRQA 1BFIA 5EHPA 3VS5A 3VS7A 1IS0A 2AOAA 1O4HA 3MAZA 2MK2A 1AOUF 1OPKA 4JEGA 1O4BA 2L3TA 2LNWA 1TCEA 2DCRA 4F5AA 1FBZA 2RVFA 1SHBA 1LCJA 3IMJA 1R1QA 2K79B 1OO3A 2SRCA 4GL9E 4EIHA 1KSWA 2FCIA 3BUOB 5GJIA 1BM2A 1OPLA 2C9WA 4E68A 3GQIB 4L1BB 4OHDA 1KC2A 4F5BA 1O4EA 1O43A 2YU7A 4GPLB 4FL3A 3T04A 5HKWA 1NZVA 3UF4A 3BUMB 4TZIA 3S8LA 1A07A 1O4CA 2AOBA 1UUSA 4WWQA 1FYRA 5HKZA 1BHHB 4OHIA 2RSYA 2EOBA 1X27A 1YVHA 2DLYA 1O4AA 2QMSA 2OQ1A 3BUWB 1B47A 2LQNA 1XA6A 4QSYA 1HCTB 1R1PA 3PS5A 1AYAA 1A1BA 3KFJA 4U17A 3US4A 3M7FA 2EU0A 5EEQA 2RMXA 1BKLA 2EYVA 2MQIA 3IMDA 1A81A 1TZEE 2K7AB 4OHEA 1LKKA 2PTKA 5GJHA 5KAZA 2KK6A 1SHAA 1AB2A 2SHPA 1LUKA 4OHLA 3PFVA 1AYCA 3K2MA 1FMKA 2Y3AB 1AD5A 3EAZA 1O42A 2ABLA 2HCKA 2EKXA 3QWYA 1JU5A 1O4JA 1CSZA 1O47A 3VROA 4DGXA 2DX0A 1F1WA 3VS6A 1GHUA 1M61A 1AOTF 1SKJA 3UYOA 1LKLA 1Z3KA 4FL2A 2H46E 5IBMA 1O4RA 2CI9A 1MW4A 2RORA 3OVEA 3VRYA 2DM0A 4F59A 5EELA 2IUIA 3S8NA 3VS4A 1JYRA 1O4NA 5CDWA 3MXCA 4ROJA 3PSJA 1LUNA 1P13A 1O4GA 1JYUA 4FBNA 3PSKA 2GE9A 5J3XA 1BLJA 3MXYA 1CWEA 2LNXA 4GWFA 1O4DA 1AYDA 1O45A 1D4TA 1OO4A 3HCKA 3N7YA 1F2FA 4EY0A 1A09A 3VS3A 1CJ1A 3EACA 4DGPA 1LCKA 3N8MA 5DC4A 2ECDA 2JYQA 1QADA 2CR4A 2H5KA 1YVLA 3OV1A 2B3OA 2ETZA 2EL8A 1O49A 2CIAA 2EO6A 1MILA 3VRNA 1CSYA 1NRVA 5D0JA 1RPYA 3TKZA 1PICA 3GXWA 3CD3A 2MC1A 5AULA 4H34A 4XZ1A 3VS2A 2L6KA 1G83A 2EYYA 1RJAA 4JGHA 2VIFA 3OB1B 1I3ZA 1LUMA 1O4PA 1FHSA 2IZVA 1O4MA 1SPSA 1SPRA 3VS0A 2HMHA 2H8HA 5DC9A 1A1AA 4NWFA 5HKYA 1BHHA 1O44A 1WQUA 2HUWA 4X6SA 2AUGA 1BFJA 4D8KA 3VRZA 3C7IA 2LQWA 2CS0A 1BKMA 1AYBA 1RQQC 1X6CA 2PLEA 5I6VA 1CWDL 2CI8A 4NWGA 2IUGA 2MRKA 2XP1A 1ZFPE 4K2RA 1O41A 4A4CA 1QCFA 1FBVA 3BUXB 3S8OA 2Y1NA 1IJRA 1Y1UA 4XZ0A 3BUNB 1NZLA 1O4QA 4U1PA 3S9KA 2EYZA 4A4BA 1A08A 3PLFB 2YSXA 3CBLA 4OHHA 1JWOA 3N84A 2MRJA 4E93A 5AXIA 2LCTA 2C0IA 1JYQA 1QG1E 5IBSA 4K45A 3OB2B 4LUEA 1O4FA 2L4KA 1HCSB 2BBUA 3IN8A 1O4IA 3VS1A 2IUHA 2FO0A 1LUIA 1A1EA 3PQZA 3IN7A 2CBLA 4JE4A 2Y1MA 3VGOA 3HIZB 5DC0B 1Y57A 1O4KA 3TL0A 3QWXX 3HHMB 3NHNA 2HDXA 3VRRA 1BG1A 4K11A 1BHFA 1BF5A 3PJPA 1O46A 4P9VA 3ZNIA 1BMBA 1FU6A 2C0TA 2EO3A 1O48A 1D1ZA 4P9ZA 1O4LA 5BO4A 1BLKA 1X0NA 1M27A 2OZOA 5EHRA 1D4WA 1KA6A 2GSBA 1GRIA 3CWGA 4LUDA 2HDVA 1H9OA 2C0OA 1FU5A 3OP0A 3WA4A 4M4ZA 2PLDA 5EG3B 2PNAA 1A1CA 3GXXA 4H1OA
chains in the Genus database with same CATH superfamily
5DF6A 1R1SA 3BKBA 2KNOA 1KA7A 3VRPA 2CRHA 4K44A 1UURA 3CXLA 1O4OA 1SHDA 2DLZA 2DVJA 2PNBA 1K9AA 3VRQA 1BFIA 5EHPA 3VS5A 3VS7A 1IS0A 2AOAA 1O4HA 3MAZA 2MK2A 1AOUF 1OPKA 4JEGA 1O4BA 2L3TA 2LNWA 1TCEA 2DCRA 4F5AA 1FBZA 2RVFA 1SHBA 1LCJA 3IMJA 1R1QA 2K79B 1OO3A 2SRCA 4GL9E 4EIHA 1KSWA 2FCIA 3BUOB 5GJIA 1BM2A 1OPLA 2C9WA 4E68A 4OHDA 3GQIB 4L1BB 1KC2A 4F5BA 1O4EA 1O43A 2YU7A 4GPLB 4FL3A 3T04A 5HKWA 1NZVA 3UF4A 3BUMB 4TZIA 3S8LA 1A07A 1O4CA 2AOBA 1UUSA 4WWQA 1FYRA 5HKZA 1BHHB 4OHIA 2RSYA 2EOBA 1X27A 1YVHA 2DLYA 1O4AA 2QMSA 2OQ1A 3BUWB 1B47A 2LQNA 1XA6A 4QSYA 1HCTB 1R1PA 3PS5A 1AYAA 1A1BA 3KFJA 4U17A 3US4A 3M7FA 2EU0A 5EEQA 2RMXA 1BKLA 2EYVA 2MQIA 3IMDA 1A81A 1TZEE 2K7AB 4OHEA 1LKKA 2PTKA 5GJHA 5KAZA 2KK6A 1SHAA 1AB2A 2SHPA 1LUKA 4OHLA 3PFVA 1AYCA 3K2MA 1FMKA 2Y3AB 1AD5A 3EAZA 1O42A 2ABLA 2HCKA 2EKXA 3QWYA 1JU5A 1O4JA 1CSZA 1O47A 3VROA 4DGXA 2DX0A 1F1WA 3VS6A 1GHUA 1M61A 1AOTF 1SKJA 3UYOA 2KGYA 1LKLA 1Z3KA 4FL2A 2H46E 5IBMA 1O4RA 2CI9A 1MW4A 2RORA 3OVEA 3VRYA 2DM0A 4F59A 5EELA 2IUIA 3S8NA 3VS4A 1JYRA 1O4NA 5CDWA 3MXCA 4ROJA 3PSJA 1LUNA 1P13A 1O4GA 1JYUA 4FBNA 3PSKA 2GE9A 5J3XA 1BLJA 3MXYA 1CWEA 2LNXA 4GWFA 1O4DA 1AYDA 1O45A 1D4TA 1OO4A 3HCKA 3N7YA 1F2FA 4EY0A 1A09A 3VS3A 1CJ1A 3EACA 4DGPA 1LCKA 3N8MA 5DC4A 2ECDA 2JYQA 1QADA 2CR4A 2H5KA 1YVLA 3OV1A 2B3OA 2ETZA 2EL8A 1O49A 2CIAA 2EO6A 1MILA 3VRNA 1CSYA 1NRVA 5D0JA 1RPYA 3TKZA 1PICA 3GXWA 3CD3A 2MC1A 5AULA 4H34A 4XZ1A 3VS2A 2L6KA 1G83A 2EYYA 1RJAA 4JGHA 2VIFA 3OB1B 1I3ZA 1LUMA 1O4PA 1FHSA 2IZVA 1O4MA 1SPSA 1SPRA 3VS0A 2HMHA 2H8HA 5DC9A 1A1AA 4NWFA 5HKYA 1BHHA 1O44A 1WQUA 2HUWA 4X6SA 2AUGA 1BFJA 4D8KA 3VRZA 3C7IA 2LQWA 2CS0A 1BKMA 1AYBA 1RQQC 1X6CA 2PLEA 5I6VA 1CWDL 2CI8A 4NWGA 2IUGA 2MRKA 2XP1A 1ZFPE 4K2RA 1O41A 4A4CA 1QCFA 1FBVA 3BUXB 3S8OA 2Y1NA 1IJRA 1Y1UA 4XZ0A 3BUNB 1NZLA 1O4QA 4U1PA 3S9KA 2EYZA 4A4BA 1A08A 3PLFB 2YSXA 3CBLA 4OHHA 1JWOA 3N84A 2MRJA 4E93A 2LRAA 5AXIA 2LCTA 2C0IA 1JYQA 1QG1E 5IBSA 4K45A 3OB2B 4LUEA 1O4FA 2L4KA 1HCSB 2BBUA 3IN8A 1O4IA 3VS1A 2IUHA 2FO0A 1LUIA 1A1EA 3PQZA 3IN7A 2CBLA 4JE4A 2Y1MA 3VGOA 3HIZB 5DC0B 1Y57A 1O4KA 3TL0A 3QWXX 3HHMB 3NHNA 2HDXA 3VRRA 1BG1A 4K11A 1BHFA 3K2TA 1BF5A 3PJPA 1O46A 4P9VA 3ZNIA 1BMBA 1FU6A 2C0TA 2EO3A 1O48A 1D1ZA 4P9ZA 1O4LA 5BO4A 1BLKA 1X0NA 1M27A 2OZOA 5EHRA 1D4WA 1KA6A 2GSBA 1GRIA 3CWGA 4LUDA 2HDVA 3LYVA 1H9OA 2C0OA 1FU5A 3OP0A 3WA4A 4M4ZA 2PLDA 5EG3B 2PNAA 1A1CA 3GXXA 4H1OA
chains in the Genus database with same CATH topology
5DF6A 1R1SA 3BKBA 2KNOA 1KA7A 3VRPA 2CRHA 4K44A 1UURA 3CXLA 1O4OA 1SHDA 2DLZA 2DVJA 2PNBA 1K9AA 3VRQA 1BFIA 5EHPA 3VS5A 3VS7A 1IS0A 2AOAA 1O4HA 3MAZA 2MK2A 1AOUF 1OPKA 4JEGA 1O4BA 2L3TA 2LNWA 1TCEA 2DCRA 4F5AA 1FBZA 2RVFA 1SHBA 1LCJA 3IMJA 1R1QA 2K79B 1OO3A 2SRCA 4GL9E 4EIHA 1KSWA 2FCIA 3BUOB 5GJIA 1BM2A 1OPLA 2C9WA 4E68A 3GQIB 4L1BB 4OHDA 1KC2A 4F5BA 1O4EA 1O43A 2YU7A 4GPLB 4FL3A 3T04A 5HKWA 1NZVA 3UF4A 3BUMB 4TZIA 3S8LA 1A07A 1O4CA 2AOBA 1UUSA 4WWQA 1FYRA 5HKZA 1BHHB 4OHIA 2RSYA 2EOBA 1X27A 1YVHA 2DLYA 1O4AA 2QMSA 2OQ1A 3BUWB 1B47A 2LQNA 1XA6A 4QSYA 1HCTB 1R1PA 3PS5A 1AYAA 1A1BA 3KFJA 4U17A 3US4A 3M7FA 2EU0A 5EEQA 2RMXA 1BKLA 2EYVA 2MQIA 3IMDA 1A81A 1TZEE 2K7AB 4OHEA 1LKKA 2PTKA 5GJHA 5KAZA 2KK6A 1SHAA 1AB2A 2SHPA 1LUKA 4OHLA 3PFVA 1AYCA 3K2MA 1FMKA 2Y3AB 1AD5A 3EAZA 1O42A 2ABLA 2HCKA 2EKXA 3QWYA 1JU5A 1O4JA 1CSZA 1O47A 3VROA 4DGXA 2DX0A 1F1WA 3VS6A 1GHUA 1M61A 1AOTF 1SKJA 3UYOA 1LKLA 1Z3KA 4FL2A 2H46E 5IBMA 1O4RA 2CI9A 1MW4A 2RORA 3OVEA 3VRYA 2DM0A 4F59A 5EELA 2IUIA 3S8NA 3VS4A 1JYRA 1O4NA 5CDWA 3MXCA 4ROJA 3PSJA 1LUNA 1P13A 1O4GA 1JYUA 4FBNA 3PSKA 2GE9A 5J3XA 1BLJA 3MXYA 1CWEA 2LNXA 4GWFA 1O4DA 1AYDA 1O45A 1D4TA 1OO4A 3HCKA 3N7YA 1F2FA 4EY0A 1A09A 3VS3A 1CJ1A 3EACA 4DGPA 1LCKA 3N8MA 5DC4A 2ECDA 2JYQA 1QADA 2CR4A 2H5KA 1YVLA 3OV1A 2B3OA 2ETZA 2EL8A 1O49A 2CIAA 2EO6A 1MILA 3VRNA 1CSYA 1NRVA 5D0JA 1RPYA 3TKZA 1PICA 3GXWA 3CD3A 2MC1A 5AULA 4H34A 4XZ1A 3VS2A 2L6KA 1G83A 2EYYA 1RJAA 4JGHA 2VIFA 3OB1B 1I3ZA 1LUMA 1O4PA 1FHSA 2IZVA 1O4MA 1SPSA 1SPRA 3VS0A 2HMHA 2H8HA 5DC9A 1A1AA 4NWFA 5HKYA 1BHHA 1O44A 1WQUA 2HUWA 4X6SA 2AUGA 1BFJA 4D8KA 3VRZA 3C7IA 2LQWA 2CS0A 1BKMA 1AYBA 1RQQC 1X6CA 2PLEA 5I6VA 1CWDL 2CI8A 4NWGA 2IUGA 2MRKA 2XP1A 1ZFPE 4K2RA 1O41A 4A4CA 1QCFA 1FBVA 3BUXB 3S8OA 2Y1NA 1IJRA 1Y1UA 4XZ0A 3BUNB 1NZLA 1O4QA 4U1PA 3S9KA 2EYZA 4A4BA 1A08A 3PLFB 2YSXA 3CBLA 4OHHA 1JWOA 3N84A 2MRJA 4E93A 5AXIA 2LCTA 2C0IA 1JYQA 1QG1E 5IBSA 4K45A 3OB2B 4LUEA 1O4FA 2L4KA 1HCSB 2BBUA 3IN8A 1O4IA 3VS1A 2IUHA 2FO0A 1LUIA 1A1EA 3PQZA 3IN7A 2CBLA 4JE4A 2Y1MA 3VGOA 3HIZB 5DC0B 1Y57A 1O4KA 3TL0A 3QWXX 3HHMB 3NHNA 2HDXA 3VRRA 1BG1A 4K11A 1BHFA 1BF5A 3PJPA 1O46A 4P9VA 3ZNIA 1BMBA 1FU6A 2C0TA 2EO3A 1O48A 1D1ZA 4P9ZA 1O4LA 5BO4A 1BLKA 1X0NA 1M27A 2OZOA 5EHRA 1D4WA 1KA6A 2GSBA 1GRIA 3CWGA 4LUDA 2HDVA 1H9OA 2C0OA 1FU5A 3OP0A 3WA4A 4M4ZA 2PLDA 5EG3B 2PNAA 1A1CA 3GXXA 4H1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DF6 A;  1R1S A;  3BKB A;  2KNO A;  1KA7 A;  3VRP A;  2CRH A;  4K44 A;  1UUR A;  3CXL A;  1O4O A;  1SHD A;  2DLZ A;  2DVJ A;  2PNB A;  1K9A A;  3VRQ A;  1BFI A;  5EHP A;  3VS5 A;  3VS7 A;  1IS0 A;  2AOA A;  1O4H A;  3MAZ A;  2MK2 A;  1AOU F;  1OPK A;  4JEG A;  1O4B A;  2L3T A;  2LNW A;  1TCE A;  2DCR A;  4F5A A;  1FBZ A;  2RVF A;  1SHB A;  1LCJ A;  3IMJ A;  1R1Q A;  2K79 B;  1OO3 A;  2SRC A;  4GL9 E;  4EIH A;  1KSW A;  2FCI A;  3BUO B;  5GJI A;  1BM2 A;  1OPL A;  2C9W A;  4E68 A;  3GQI B;  4L1B B;  4OHD A;  1KC2 A;  4F5B A;  1O4E A;  1O43 A;  2YU7 A;  4GPL B;  4FL3 A;  3T04 A;  5HKW A;  1NZV A;  3UF4 A;  3BUM B;  4TZI A;  3S8L A;  1A07 A;  1O4C A;  2AOB A;  1UUS A;  4WWQ A;  1FYR A;  5HKZ A;  1BHH B;  4OHI A;  2RSY A;  2EOB A;  1X27 A;  1YVH A;  2DLY A;  1O4A A;  2QMS A;  2OQ1 A;  3BUW B;  1B47 A;  2LQN A;  1XA6 A;  4QSY A;  1HCT B;  1R1P A;  3PS5 A;  1AYA A;  1A1B A;  3KFJ A;  4U17 A;  3US4 A;  3M7F A;  2EU0 A;  5EEQ A;  2RMX A;  1BKL A;  2EYV A;  2MQI A;  3IMD A;  1A81 A;  1TZE E;  2K7A B;  4OHE A;  1LKK A;  2PTK A;  5GJH A;  5KAZ A;  2KK6 A;  1SHA A;  1AB2 A;  2SHP A;  1LUK A;  4OHL A;  3PFV A;  1AYC A;  3K2M A;  1FMK A;  2Y3A B;  1AD5 A;  3EAZ A;  1O42 A;  2ABL A;  2HCK A;  2EKX A;  3QWY A;  1JU5 A;  1O4J A;  1CSZ A;  1O47 A;  3VRO A;  4DGX A;  2DX0 A;  1F1W A;  3VS6 A;  1GHU A;  1M61 A;  1AOT F;  1SKJ A;  3UYO A;  1LKL A;  1Z3K A;  4FL2 A;  2H46 E;  5IBM A;  1O4R A;  2CI9 A;  1MW4 A;  2ROR A;  3OVE A;  3VRY A;  2DM0 A;  4F59 A;  5EEL A;  2IUI A;  3S8N A;  3VS4 A;  1JYR A;  1O4N A;  5CDW A;  3MXC A;  4ROJ A;  3PSJ A;  1LUN A;  1P13 A;  1O4G A;  1JYU A;  4FBN A;  3PSK A;  2GE9 A;  5J3X A;  1BLJ A;  3MXY A;  1CWE A;  2LNX A;  4GWF A;  1O4D A;  1AYD A;  1O45 A;  1D4T A;  1OO4 A;  3HCK A;  3N7Y A;  1F2F A;  4EY0 A;  1A09 A;  3VS3 A;  1CJ1 A;  3EAC A;  4DGP A;  1LCK A;  3N8M A;  5DC4 A;  2ECD A;  2JYQ A;  1QAD A;  2CR4 A;  2H5K A;  1YVL A;  3OV1 A;  2B3O A;  2ETZ A;  2EL8 A;  1O49 A;  2CIA A;  2EO6 A;  1MIL A;  3VRN A;  1CSY A;  1NRV A;  5D0J A;  1RPY A;  3TKZ A;  1PIC A;  3GXW A;  3CD3 A;  2MC1 A;  5AUL A;  4H34 A;  4XZ1 A;  3VS2 A;  2L6K A;  1G83 A;  2EYY A;  1RJA A;  4JGH A;  2VIF A;  3OB1 B;  1I3Z A;  1LUM A;  1O4P A;  1FHS A;  2IZV A;  1O4M A;  1SPS A;  1SPR A;  3VS0 A;  2HMH A;  2H8H A;  5DC9 A;  1A1A A;  4NWF A;  5HKY A;  1BHH A;  1O44 A;  1WQU A;  2HUW A;  4X6S A;  2AUG A;  1BFJ A;  4D8K A;  3VRZ A;  3C7I A;  2LQW A;  2CS0 A;  1BKM A;  1AYB A;  1RQQ C;  1X6C A;  2PLE A;  5I6V A;  1CWD L;  2CI8 A;  4NWG A;  2IUG A;  2MRK A;  2XP1 A;  1ZFP E;  4K2R A;  1O41 A;  4A4C A;  1QCF A;  1FBV A;  3BUX B;  3S8O A;  2Y1N A;  1IJR A;  1Y1U A;  4XZ0 A;  3BUN B;  1NZL A;  1O4Q A;  4U1P A;  3S9K A;  2EYZ A;  4A4B A;  1A08 A;  3PLF B;  2YSX A;  3CBL A;  4OHH A;  1JWO A;  3N84 A;  2MRJ A;  4E93 A;  5AXI A;  2LCT A;  2C0I A;  1JYQ A;  1QG1 E;  5IBS A;  4K45 A;  3OB2 B;  4LUE A;  1O4F A;  2L4K A;  1HCS B;  2BBU A;  3IN8 A;  1O4I A;  3VS1 A;  2IUH A;  2FO0 A;  1LUI A;  1A1E A;  3PQZ A;  3IN7 A;  2CBL A;  4JE4 A;  2Y1M A;  3VGO A;  3HIZ B;  5DC0 B;  1Y57 A;  1O4K A;  3TL0 A;  3QWX X;  3HHM B;  3NHN A;  2HDX A;  3VRR A;  1BG1 A;  4K11 A;  1BHF A;  1BF5 A;  3PJP A;  1O46 A;  4P9V A;  3ZNI A;  1BMB A;  1FU6 A;  2C0T A;  2EO3 A;  1O48 A;  1D1Z A;  4P9Z A;  1O4L A;  5BO4 A;  1BLK A;  1X0N A;  1M27 A;  2OZO A;  5EHR A;  1D4W A;  1KA6 A;  2GSB A;  1GRI A;  3CWG A;  4LUD A;  2HDV A;  1H9O A;  2C0O A;  1FU5 A;  3OP0 A;  3WA4 A;  4M4Z A;  2PLD A;  5EG3 B;  2PNA A;  1A1C A;  3GXX A;  4H1O A; 
#chains in the Genus database with same CATH topology
 5DF6 A;  1R1S A;  3BKB A;  2KNO A;  1KA7 A;  3VRP A;  2CRH A;  4K44 A;  1UUR A;  3CXL A;  1O4O A;  1SHD A;  2DLZ A;  2DVJ A;  2PNB A;  1K9A A;  3VRQ A;  1BFI A;  5EHP A;  3VS5 A;  3VS7 A;  1IS0 A;  2AOA A;  1O4H A;  3MAZ A;  2MK2 A;  1AOU F;  1OPK A;  4JEG A;  1O4B A;  2L3T A;  2LNW A;  1TCE A;  2DCR A;  4F5A A;  1FBZ A;  2RVF A;  1SHB A;  1LCJ A;  3IMJ A;  1R1Q A;  2K79 B;  1OO3 A;  2SRC A;  4GL9 E;  4EIH A;  1KSW A;  2FCI A;  3BUO B;  5GJI A;  1BM2 A;  1OPL A;  2C9W A;  4E68 A;  4OHD A;  3GQI B;  4L1B B;  1KC2 A;  4F5B A;  1O4E A;  1O43 A;  2YU7 A;  4GPL B;  4FL3 A;  3T04 A;  5HKW A;  1NZV A;  3UF4 A;  3BUM B;  4TZI A;  3S8L A;  1A07 A;  1O4C A;  2AOB A;  1UUS A;  4WWQ A;  1FYR A;  5HKZ A;  1BHH B;  4OHI A;  2RSY A;  2EOB A;  1X27 A;  1YVH A;  2DLY A;  1O4A A;  2QMS A;  2OQ1 A;  3BUW B;  1B47 A;  2LQN A;  1XA6 A;  4QSY A;  1HCT B;  1R1P A;  3PS5 A;  1AYA A;  1A1B A;  3KFJ A;  4U17 A;  3US4 A;  3M7F A;  2EU0 A;  5EEQ A;  2RMX A;  1BKL A;  2EYV A;  2MQI A;  3IMD A;  1A81 A;  1TZE E;  2K7A B;  4OHE A;  1LKK A;  2PTK A;  5GJH A;  5KAZ A;  2KK6 A;  1SHA A;  1AB2 A;  2SHP A;  1LUK A;  4OHL A;  3PFV A;  1AYC A;  3K2M A;  1FMK A;  2Y3A B;  1AD5 A;  3EAZ A;  1O42 A;  2ABL A;  2HCK A;  2EKX A;  3QWY A;  1JU5 A;  1O4J A;  1CSZ A;  1O47 A;  3VRO A;  4DGX A;  2DX0 A;  1F1W A;  3VS6 A;  1GHU A;  1M61 A;  1AOT F;  1SKJ A;  3UYO A;  2KGY A;  1LKL A;  1Z3K A;  4FL2 A;  2H46 E;  5IBM A;  1O4R A;  2CI9 A;  1MW4 A;  2ROR A;  3OVE A;  3VRY A;  2DM0 A;  4F59 A;  5EEL A;  2IUI A;  3S8N A;  3VS4 A;  1JYR A;  1O4N A;  5CDW A;  3MXC A;  4ROJ A;  3PSJ A;  1LUN A;  1P13 A;  1O4G A;  1JYU A;  4FBN A;  3PSK A;  2GE9 A;  5J3X A;  1BLJ A;  3MXY A;  1CWE A;  2LNX A;  4GWF A;  1O4D A;  1AYD A;  1O45 A;  1D4T A;  1OO4 A;  3HCK A;  3N7Y A;  1F2F A;  4EY0 A;  1A09 A;  3VS3 A;  1CJ1 A;  3EAC A;  4DGP A;  1LCK A;  3N8M A;  5DC4 A;  2ECD A;  2JYQ A;  1QAD A;  2CR4 A;  2H5K A;  1YVL A;  3OV1 A;  2B3O A;  2ETZ A;  2EL8 A;  1O49 A;  2CIA A;  2EO6 A;  1MIL A;  3VRN A;  1CSY A;  1NRV A;  5D0J A;  1RPY A;  3TKZ A;  1PIC A;  3GXW A;  3CD3 A;  2MC1 A;  5AUL A;  4H34 A;  4XZ1 A;  3VS2 A;  2L6K A;  1G83 A;  2EYY A;  1RJA A;  4JGH A;  2VIF A;  3OB1 B;  1I3Z A;  1LUM A;  1O4P A;  1FHS A;  2IZV A;  1O4M A;  1SPS A;  1SPR A;  3VS0 A;  2HMH A;  2H8H A;  5DC9 A;  1A1A A;  4NWF A;  5HKY A;  1BHH A;  1O44 A;  1WQU A;  2HUW A;  4X6S A;  2AUG A;  1BFJ A;  4D8K A;  3VRZ A;  3C7I A;  2LQW A;  2CS0 A;  1BKM A;  1AYB A;  1RQQ C;  1X6C A;  2PLE A;  5I6V A;  1CWD L;  2CI8 A;  4NWG A;  2IUG A;  2MRK A;  2XP1 A;  1ZFP E;  4K2R A;  1O41 A;  4A4C A;  1QCF A;  1FBV A;  3BUX B;  3S8O A;  2Y1N A;  1IJR A;  1Y1U A;  4XZ0 A;  3BUN B;  1NZL A;  1O4Q A;  4U1P A;  3S9K A;  2EYZ A;  4A4B A;  1A08 A;  3PLF B;  2YSX A;  3CBL A;  4OHH A;  1JWO A;  3N84 A;  2MRJ A;  4E93 A;  2LRA A;  5AXI A;  2LCT A;  2C0I A;  1JYQ A;  1QG1 E;  5IBS A;  4K45 A;  3OB2 B;  4LUE A;  1O4F A;  2L4K A;  1HCS B;  2BBU A;  3IN8 A;  1O4I A;  3VS1 A;  2IUH A;  2FO0 A;  1LUI A;  1A1E A;  3PQZ A;  3IN7 A;  2CBL A;  4JE4 A;  2Y1M A;  3VGO A;  3HIZ B;  5DC0 B;  1Y57 A;  1O4K A;  3TL0 A;  3QWX X;  3HHM B;  3NHN A;  2HDX A;  3VRR A;  1BG1 A;  4K11 A;  1BHF A;  3K2T A;  1BF5 A;  3PJP A;  1O46 A;  4P9V A;  3ZNI A;  1BMB A;  1FU6 A;  2C0T A;  2EO3 A;  1O48 A;  1D1Z A;  4P9Z A;  1O4L A;  5BO4 A;  1BLK A;  1X0N A;  1M27 A;  2OZO A;  5EHR A;  1D4W A;  1KA6 A;  2GSB A;  1GRI A;  3CWG A;  4LUD A;  2HDV A;  3LYV A;  1H9O A;  2C0O A;  1FU5 A;  3OP0 A;  3WA4 A;  4M4Z A;  2PLD A;  5EG3 B;  2PNA A;  1A1C A;  3GXX A;  4H1O A; 
#chains in the Genus database with same CATH homology
 5DF6 A;  1R1S A;  3BKB A;  2KNO A;  1KA7 A;  3VRP A;  2CRH A;  4K44 A;  1UUR A;  3CXL A;  1O4O A;  1SHD A;  2DLZ A;  2DVJ A;  2PNB A;  1K9A A;  3VRQ A;  1BFI A;  5EHP A;  3VS5 A;  3VS7 A;  1IS0 A;  2AOA A;  1O4H A;  3MAZ A;  2MK2 A;  1AOU F;  1OPK A;  4JEG A;  1O4B A;  2L3T A;  2LNW A;  1TCE A;  2DCR A;  4F5A A;  1FBZ A;  2RVF A;  1SHB A;  1LCJ A;  3IMJ A;  1R1Q A;  2K79 B;  1OO3 A;  2SRC A;  4GL9 E;  4EIH A;  1KSW A;  2FCI A;  3BUO B;  5GJI A;  1BM2 A;  1OPL A;  2C9W A;  4E68 A;  3GQI B;  4L1B B;  4OHD A;  1KC2 A;  4F5B A;  1O4E A;  1O43 A;  2YU7 A;  4GPL B;  4FL3 A;  3T04 A;  5HKW A;  1NZV A;  3UF4 A;  3BUM B;  4TZI A;  3S8L A;  1A07 A;  1O4C A;  2AOB A;  1UUS A;  4WWQ A;  1FYR A;  5HKZ A;  1BHH B;  4OHI A;  2RSY A;  2EOB A;  1X27 A;  1YVH A;  2DLY A;  1O4A A;  2QMS A;  2OQ1 A;  3BUW B;  1B47 A;  2LQN A;  1XA6 A;  4QSY A;  1HCT B;  1R1P A;  3PS5 A;  1AYA A;  1A1B A;  3KFJ A;  4U17 A;  3US4 A;  3M7F A;  2EU0 A;  5EEQ A;  2RMX A;  1BKL A;  2EYV A;  2MQI A;  3IMD A;  1A81 A;  1TZE E;  2K7A B;  4OHE A;  1LKK A;  2PTK A;  5GJH A;  5KAZ A;  2KK6 A;  1SHA A;  1AB2 A;  2SHP A;  1LUK A;  4OHL A;  3PFV A;  1AYC A;  3K2M A;  1FMK A;  2Y3A B;  1AD5 A;  3EAZ A;  1O42 A;  2ABL A;  2HCK A;  2EKX A;  3QWY A;  1JU5 A;  1O4J A;  1CSZ A;  1O47 A;  3VRO A;  4DGX A;  2DX0 A;  1F1W A;  3VS6 A;  1GHU A;  1M61 A;  1AOT F;  1SKJ A;  3UYO A;  1LKL A;  1Z3K A;  4FL2 A;  2H46 E;  5IBM A;  1O4R A;  2CI9 A;  1MW4 A;  2ROR A;  3OVE A;  3VRY A;  2DM0 A;  4F59 A;  5EEL A;  2IUI A;  3S8N A;  3VS4 A;  1JYR A;  1O4N A;  5CDW A;  3MXC A;  4ROJ A;  3PSJ A;  1LUN A;  1P13 A;  1O4G A;  1JYU A;  4FBN A;  3PSK A;  2GE9 A;  5J3X A;  1BLJ A;  3MXY A;  1CWE A;  2LNX A;  4GWF A;  1O4D A;  1AYD A;  1O45 A;  1D4T A;  1OO4 A;  3HCK A;  3N7Y A;  1F2F A;  4EY0 A;  1A09 A;  3VS3 A;  1CJ1 A;  3EAC A;  4DGP A;  1LCK A;  3N8M A;  5DC4 A;  2ECD A;  2JYQ A;  1QAD A;  2CR4 A;  2H5K A;  1YVL A;  3OV1 A;  2B3O A;  2ETZ A;  2EL8 A;  1O49 A;  2CIA A;  2EO6 A;  1MIL A;  3VRN A;  1CSY A;  1NRV A;  5D0J A;  1RPY A;  3TKZ A;  1PIC A;  3GXW A;  3CD3 A;  2MC1 A;  5AUL A;  4H34 A;  4XZ1 A;  3VS2 A;  2L6K A;  1G83 A;  2EYY A;  1RJA A;  4JGH A;  2VIF A;  3OB1 B;  1I3Z A;  1LUM A;  1O4P A;  1FHS A;  2IZV A;  1O4M A;  1SPS A;  1SPR A;  3VS0 A;  2HMH A;  2H8H A;  5DC9 A;  1A1A A;  4NWF A;  5HKY A;  1BHH A;  1O44 A;  1WQU A;  2HUW A;  4X6S A;  2AUG A;  1BFJ A;  4D8K A;  3VRZ A;  3C7I A;  2LQW A;  2CS0 A;  1BKM A;  1AYB A;  1RQQ C;  1X6C A;  2PLE A;  5I6V A;  1CWD L;  2CI8 A;  4NWG A;  2IUG A;  2MRK A;  2XP1 A;  1ZFP E;  4K2R A;  1O41 A;  4A4C A;  1QCF A;  1FBV A;  3BUX B;  3S8O A;  2Y1N A;  1IJR A;  1Y1U A;  4XZ0 A;  3BUN B;  1NZL A;  1O4Q A;  4U1P A;  3S9K A;  2EYZ A;  4A4B A;  1A08 A;  3PLF B;  2YSX A;  3CBL A;  4OHH A;  1JWO A;  3N84 A;  2MRJ A;  4E93 A;  5AXI A;  2LCT A;  2C0I A;  1JYQ A;  1QG1 E;  5IBS A;  4K45 A;  3OB2 B;  4LUE A;  1O4F A;  2L4K A;  1HCS B;  2BBU A;  3IN8 A;  1O4I A;  3VS1 A;  2IUH A;  2FO0 A;  1LUI A;  1A1E A;  3PQZ A;  3IN7 A;  2CBL A;  4JE4 A;  2Y1M A;  3VGO A;  3HIZ B;  5DC0 B;  1Y57 A;  1O4K A;  3TL0 A;  3QWX X;  3HHM B;  3NHN A;  2HDX A;  3VRR A;  1BG1 A;  4K11 A;  1BHF A;  1BF5 A;  3PJP A;  1O46 A;  4P9V A;  3ZNI A;  1BMB A;  1FU6 A;  2C0T A;  2EO3 A;  1O48 A;  1D1Z A;  4P9Z A;  1O4L A;  5BO4 A;  1BLK A;  1X0N A;  1M27 A;  2OZO A;  5EHR A;  1D4W A;  1KA6 A;  2GSB A;  1GRI A;  3CWG A;  4LUD A;  2HDV A;  1H9O A;  2C0O A;  1FU5 A;  3OP0 A;  3WA4 A;  4M4Z A;  2PLD A;  5EG3 B;  2PNA A;  1A1C A;  3GXX A;  4H1O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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