1O4AA

Crystal structure of sh2 in complex with ru82197.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4aA00
1D4WA 1QG1E 1BHHB 3VS6A 4EIHA 1LUIA 1AD5A 2FCIA 1OO4A 1G83A 1CJ1A 2H46E 1XA6A 2AOAA 2C0OA 4NWFA 3VS2A 1BG1A 4FBNA 2LNXA 5CDWA 1HCSB 3HCKA 1FBVA 3TKZA 3PQZA 3BUMB 1NZVA 1O44A 1TZEE 5DC4A 1SHDA 1Y57A 1F1WA 1QADA 1A1EA 2ABLA 2CI9A 2EYVA 2PNBA 5HKWA 4LUEA 4M4ZA 2CIAA 3GQIB 3VS7A 3VS5A 5DC0B 3PJPA 3N84A 1A09A 1X0NA 3OP0A 1X27A 2LCTA 1F2FA 3PSJA 1SPSA 3IN7A 5HKYA 3T04A 4U1PA 5IBMA 1AOUF 1KC2A 2H5KA 1O4BA 1M61A 1BMBA 1I3ZA 3MXCA 1NRVA 4NWGA 2SHPA 4F5AA 2C0IA 3VS0A 1KA7A 1D1ZA 2IUHA 1B47A 1BKMA 4OHDA 1NZLA 3UF4A 1GHUA 2L3TA 1MILA 3EAZA 5EELA 3WA4A 3GXXA 4K2RA 1FHSA 1H9OA 1IS0A 2CS0A 2RVFA 2Y3AB 3S9KA 1A07A 4FL2A 4K45A 3QWXX 2JYQA 5DC9A 1O4IA 4A4BA 4OHIA 1BF5A 1O4OA 1BHHA 2C0TA 1D4TA 2HCKA 3HIZB 2IZVA 1O4AA 1Y1UA 2GSBA 4GPLB 1AYAA 1O46A 1FYRA 3CBLA 1GRIA 2CBLA 1LKKA 3MXYA 1OO3A 2PLEA 5AXIA 1O47A 1KA6A 1O45A 1O4DA 5BO4A 4LUDA 3HHMB 1O4FA 1LCKA 2YSXA 2HDVA 1O48A 2HUWA 1WQUA 1JYUA 2XP1A 1SPRA 1A1AA 2CR4A 4P9ZA 2LQNA 1AOTF 3C7IA 3IMDA 3OV1A 4GL9E 1O4PA 1SHBA 1LKLA 3TL0A 1RQQC 1QCFA 1BLJA 3KFJA 3MAZA 3BUXB 2K7AB 3IMJA 1AB2A 2RORA 4EY0A 2SRCA 2IUIA 1LUMA 1JYQA 1FU6A 2DCRA 1BFJA 2DLYA 1O4EA 4D8KA 2B3OA 3BUNB 4F59A 2MK2A 1MW4A 2ETZA 5GJHA 3VS3A 1O4GA 4U17A 3VS4A 1R1QA 2PTKA 2MC1A 4P9VA 4F5BA 2LNWA 1Z3KA 4OHEA 3GXWA 3NHNA 3VRYA 1FMKA 2IUGA 4L1BB 2MQIA 3US4A 2KK6A 3CWGA 5AULA 1AYBA 2DLZA 2EO6A 1AYCA 3BUOB 1P13A 2Y1MA 3OVEA 1O4KA 2DX0A 2Y1NA 5GJIA 3BUWB 2EYZA 2AOBA 4E68A 1O4LA 3ZNIA 1PICA 4JEGA 4OHHA 2AUGA 1FU5A 1UUSA 1O4MA 3EACA 4K44A 1A1BA 5DF6A 2PLDA 1JU5A 1SHAA 2FO0A 3S8LA 3VRQA 1BKLA 2OZOA 5IBSA 2GE9A 3VROA 1M27A 5HKZA 5EG3B 2MRKA 2EO3A 5I6VA 2RMXA 1HCTB 3VRPA 3PLFB 1BFIA 3VGOA 3BKBA 5D0JA 1YVHA 4TZIA 2H8HA 1KSWA 1BLKA 1JYRA 1OPKA 2HMHA 4DGPA 5J3XA 4JGHA 4WWQA 2MRJA 1A08A 3IN8A 4JE4A 1A1CA 3CD3A 1O49A 3N8MA 3VS1A 4ROJA 1BM2A 4H1OA 4XZ1A 1K9AA 2QMSA 3OB1B 3M7FA 3S8NA 1CWDL 1JWOA 3K2MA 2L4KA 5KAZA 3OB2B 2EL8A 3QWYA 1X6CA 4X6SA 2RSYA 1FBZA 1UURA 4K11A 1OPLA 1SKJA 1LCJA 3PSKA 1O4NA 1ZFPE 2YU7A 1O42A 1YVLA 1O4JA 3PFVA 1TCEA 1RJAA 2DVJA 2BBUA 2EYYA 4E93A 2C9WA 2VIFA 3S8OA 1LUNA 1CSYA 1BHFA 2HDXA 2EOBA 1CSZA 1IJRA 5EHRA 1RPYA 2CRHA 1AYDA 4QSYA 2EU0A 3VRRA 2CI8A 1O41A 4H34A 2LQWA 4XZ0A 3VRNA 4OHLA 2L6KA 1A81A 1R1PA 1O4HA 4GWFA 1O4QA 1R1SA 1O4CA 3UYOA 2ECDA 4DGXA 2DM0A 2EKXA 2KNOA 3CXLA 1CWEA 3PS5A 5EEQA 1O4RA 3VRZA 1O43A 2PNAA 1LUKA 5EHPA 2OQ1A 4FL3A 4A4CA 3N7YA 2K79B
chains in the Genus database with same CATH superfamily
1D4WA 1QG1E 1BHHB 3VS6A 4EIHA 1LUIA 1AD5A 2FCIA 1OO4A 1G83A 1CJ1A 2H46E 1XA6A 2AOAA 2C0OA 4NWFA 3VS2A 1BG1A 4FBNA 2LNXA 5CDWA 1HCSB 3HCKA 1FBVA 3TKZA 3PQZA 2LRAA 3BUMB 1NZVA 1O44A 1TZEE 5DC4A 1SHDA 1Y57A 1F1WA 1QADA 1A1EA 2ABLA 2CI9A 2EYVA 2PNBA 5HKWA 4LUEA 4M4ZA 2CIAA 3GQIB 3VS7A 3VS5A 5DC0B 2KGYA 3PJPA 3N84A 1A09A 1X0NA 3OP0A 3K2TA 1X27A 2LCTA 1F2FA 3PSJA 1SPSA 3IN7A 5HKYA 3T04A 4U1PA 5IBMA 1AOUF 1KC2A 2H5KA 1O4BA 1M61A 1BMBA 1I3ZA 3MXCA 1NRVA 4NWGA 2SHPA 4F5AA 2C0IA 3VS0A 1KA7A 1D1ZA 2IUHA 1B47A 1BKMA 4OHDA 1NZLA 3UF4A 1GHUA 2L3TA 1MILA 3EAZA 5EELA 3WA4A 3GXXA 4K2RA 1FHSA 1H9OA 1IS0A 2CS0A 2RVFA 2Y3AB 3S9KA 1A07A 4FL2A 4K45A 3QWXX 2JYQA 5DC9A 1O4IA 4A4BA 4OHIA 1BF5A 1O4OA 1BHHA 2C0TA 1D4TA 2HCKA 3HIZB 2IZVA 1O4AA 1Y1UA 2GSBA 4GPLB 1AYAA 1O46A 1FYRA 3CBLA 1GRIA 2CBLA 1LKKA 3MXYA 1OO3A 2PLEA 5AXIA 1O47A 1KA6A 1O45A 1O4DA 5BO4A 4LUDA 3HHMB 1O4FA 3LYVA 1LCKA 2YSXA 2HDVA 1O48A 2HUWA 1WQUA 1JYUA 2XP1A 1SPRA 1A1AA 2CR4A 4P9ZA 2LQNA 1AOTF 3C7IA 3IMDA 3OV1A 4GL9E 1O4PA 1SHBA 1LKLA 3TL0A 1RQQC 1QCFA 1BLJA 3KFJA 3MAZA 3BUXB 2K7AB 3IMJA 1AB2A 2RORA 4EY0A 2SRCA 2IUIA 1LUMA 1JYQA 1FU6A 2DCRA 1BFJA 2DLYA 1O4EA 4D8KA 2B3OA 3BUNB 4F59A 2MK2A 1MW4A 2ETZA 5GJHA 3VS3A 1O4GA 4U17A 3VS4A 1R1QA 2PTKA 2MC1A 4P9VA 4F5BA 2LNWA 1Z3KA 4OHEA 3GXWA 3NHNA 3VRYA 1FMKA 2IUGA 4L1BB 2MQIA 3US4A 2KK6A 3CWGA 5AULA 1AYBA 2DLZA 2EO6A 1AYCA 3BUOB 1P13A 2Y1MA 3OVEA 1O4KA 2DX0A 2Y1NA 5GJIA 3BUWB 2EYZA 2AOBA 4E68A 1O4LA 3ZNIA 1PICA 4JEGA 4OHHA 2AUGA 1FU5A 1UUSA 1O4MA 3EACA 4K44A 1A1BA 5DF6A 2PLDA 1JU5A 1SHAA 2FO0A 3S8LA 3VRQA 1BKLA 2OZOA 5IBSA 2GE9A 3VROA 1M27A 5HKZA 5EG3B 2MRKA 2EO3A 5I6VA 2RMXA 1HCTB 3VRPA 3PLFB 1BFIA 3VGOA 3BKBA 5D0JA 1YVHA 4TZIA 2H8HA 1KSWA 1BLKA 1JYRA 1OPKA 2HMHA 4DGPA 5J3XA 4JGHA 4WWQA 2MRJA 1A08A 3IN8A 4JE4A 1A1CA 3CD3A 1O49A 3N8MA 3VS1A 4ROJA 1BM2A 4H1OA 4XZ1A 1K9AA 2QMSA 3OB1B 3M7FA 3S8NA 1CWDL 1JWOA 3K2MA 2L4KA 5KAZA 3OB2B 2EL8A 3QWYA 1X6CA 4X6SA 2RSYA 1FBZA 1UURA 4K11A 1OPLA 1SKJA 1LCJA 3PSKA 1O4NA 1ZFPE 2YU7A 1O42A 1YVLA 1O4JA 3PFVA 1TCEA 1RJAA 2DVJA 2BBUA 2EYYA 4E93A 2C9WA 2VIFA 3S8OA 1LUNA 1CSYA 1BHFA 2HDXA 2EOBA 1CSZA 1IJRA 5EHRA 1RPYA 2CRHA 1AYDA 4QSYA 2EU0A 3VRRA 2CI8A 1O41A 4H34A 2LQWA 4XZ0A 3VRNA 4OHLA 2L6KA 1A81A 1R1PA 1O4HA 4GWFA 1O4QA 1R1SA 1O4CA 3UYOA 2ECDA 4DGXA 2DM0A 2EKXA 2KNOA 3CXLA 1CWEA 3PS5A 5EEQA 1O4RA 3VRZA 1O43A 2PNAA 1LUKA 5EHPA 2OQ1A 4FL3A 4A4CA 3N7YA 2K79B
chains in the Genus database with same CATH topology
1D4WA 1QG1E 1BHHB 3VS6A 4EIHA 1LUIA 1AD5A 2FCIA 1OO4A 1G83A 1CJ1A 2H46E 1XA6A 2AOAA 2C0OA 4NWFA 3VS2A 1BG1A 4FBNA 2LNXA 5CDWA 1HCSB 3HCKA 1FBVA 3TKZA 3PQZA 3BUMB 1NZVA 1O44A 1TZEE 5DC4A 1SHDA 1Y57A 1F1WA 1QADA 1A1EA 2ABLA 2CI9A 2EYVA 2PNBA 5HKWA 4LUEA 4M4ZA 2CIAA 3GQIB 3VS7A 3VS5A 5DC0B 3PJPA 3N84A 1A09A 1X0NA 3OP0A 1X27A 2LCTA 1F2FA 3PSJA 1SPSA 3IN7A 5HKYA 3T04A 4U1PA 5IBMA 1AOUF 1KC2A 2H5KA 1O4BA 1M61A 1BMBA 1I3ZA 3MXCA 1NRVA 4NWGA 2SHPA 4F5AA 2C0IA 3VS0A 1KA7A 1D1ZA 2IUHA 1B47A 1BKMA 4OHDA 1NZLA 3UF4A 1GHUA 2L3TA 1MILA 3EAZA 5EELA 3WA4A 3GXXA 4K2RA 1FHSA 1H9OA 1IS0A 2CS0A 2RVFA 2Y3AB 3S9KA 1A07A 4FL2A 4K45A 3QWXX 2JYQA 5DC9A 1O4IA 4A4BA 4OHIA 1BF5A 1O4OA 1BHHA 2C0TA 1D4TA 2HCKA 3HIZB 2IZVA 1O4AA 1Y1UA 2GSBA 4GPLB 1AYAA 1O46A 1FYRA 3CBLA 1GRIA 2CBLA 1LKKA 3MXYA 1OO3A 2PLEA 5AXIA 1O47A 1KA6A 1O45A 1O4DA 5BO4A 4LUDA 3HHMB 1O4FA 1LCKA 2YSXA 2HDVA 1O48A 2HUWA 1WQUA 1JYUA 2XP1A 1SPRA 1A1AA 2CR4A 4P9ZA 2LQNA 1AOTF 3C7IA 3IMDA 3OV1A 4GL9E 1O4PA 1SHBA 1LKLA 3TL0A 1RQQC 1QCFA 1BLJA 3KFJA 3MAZA 3BUXB 2K7AB 3IMJA 1AB2A 2RORA 4EY0A 2SRCA 2IUIA 1LUMA 1JYQA 1FU6A 2DCRA 1BFJA 2DLYA 1O4EA 4D8KA 2B3OA 3BUNB 4F59A 2MK2A 1MW4A 2ETZA 5GJHA 3VS3A 1O4GA 4U17A 3VS4A 1R1QA 2PTKA 2MC1A 4P9VA 4F5BA 2LNWA 1Z3KA 4OHEA 3GXWA 3NHNA 3VRYA 1FMKA 2IUGA 4L1BB 2MQIA 3US4A 2KK6A 3CWGA 5AULA 1AYBA 2DLZA 2EO6A 1AYCA 3BUOB 1P13A 2Y1MA 3OVEA 1O4KA 2DX0A 2Y1NA 5GJIA 3BUWB 2EYZA 2AOBA 4E68A 1O4LA 3ZNIA 1PICA 4JEGA 4OHHA 2AUGA 1FU5A 1UUSA 1O4MA 3EACA 4K44A 1A1BA 5DF6A 2PLDA 1JU5A 1SHAA 2FO0A 3S8LA 3VRQA 1BKLA 2OZOA 5IBSA 2GE9A 3VROA 1M27A 5HKZA 5EG3B 2MRKA 2EO3A 5I6VA 2RMXA 1HCTB 3VRPA 3PLFB 1BFIA 3VGOA 3BKBA 5D0JA 1YVHA 4TZIA 2H8HA 1KSWA 1BLKA 1JYRA 1OPKA 2HMHA 4DGPA 5J3XA 4JGHA 4WWQA 2MRJA 1A08A 3IN8A 4JE4A 1A1CA 3CD3A 1O49A 3N8MA 3VS1A 4ROJA 1BM2A 4H1OA 4XZ1A 1K9AA 2QMSA 3OB1B 3M7FA 3S8NA 1CWDL 1JWOA 3K2MA 2L4KA 5KAZA 3OB2B 2EL8A 3QWYA 1X6CA 4X6SA 2RSYA 1FBZA 1UURA 4K11A 1OPLA 1SKJA 1LCJA 3PSKA 1O4NA 1ZFPE 2YU7A 1O42A 1YVLA 1O4JA 3PFVA 1TCEA 1RJAA 2DVJA 2BBUA 2EYYA 4E93A 2C9WA 2VIFA 3S8OA 1LUNA 1CSYA 1BHFA 2HDXA 2EOBA 1CSZA 1IJRA 5EHRA 1RPYA 2CRHA 1AYDA 4QSYA 2EU0A 3VRRA 2CI8A 1O41A 4H34A 2LQWA 4XZ0A 3VRNA 4OHLA 2L6KA 1A81A 1R1PA 1O4HA 4GWFA 1O4QA 1R1SA 1O4CA 3UYOA 2ECDA 4DGXA 2DM0A 2EKXA 2KNOA 3CXLA 1CWEA 3PS5A 5EEQA 1O4RA 3VRZA 1O43A 2PNAA 1LUKA 5EHPA 2OQ1A 4FL3A 4A4CA 3N7YA 2K79B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D4W A;  1QG1 E;  1BHH B;  3VS6 A;  4EIH A;  1LUI A;  1AD5 A;  2FCI A;  1OO4 A;  1G83 A;  1CJ1 A;  2H46 E;  1XA6 A;  2AOA A;  2C0O A;  4NWF A;  3VS2 A;  1BG1 A;  4FBN A;  2LNX A;  5CDW A;  1HCS B;  3HCK A;  1FBV A;  3TKZ A;  3PQZ A;  3BUM B;  1NZV A;  1O44 A;  1TZE E;  5DC4 A;  1SHD A;  1Y57 A;  1F1W A;  1QAD A;  1A1E A;  2ABL A;  2CI9 A;  2EYV A;  2PNB A;  5HKW A;  4LUE A;  4M4Z A;  2CIA A;  3GQI B;  3VS7 A;  3VS5 A;  5DC0 B;  3PJP A;  3N84 A;  1A09 A;  1X0N A;  3OP0 A;  1X27 A;  2LCT A;  1F2F A;  3PSJ A;  1SPS A;  3IN7 A;  5HKY A;  3T04 A;  4U1P A;  5IBM A;  1AOU F;  1KC2 A;  2H5K A;  1O4B A;  1M61 A;  1BMB A;  1I3Z A;  3MXC A;  1NRV A;  4NWG A;  2SHP A;  4F5A A;  2C0I A;  3VS0 A;  1KA7 A;  1D1Z A;  2IUH A;  1B47 A;  1BKM A;  4OHD A;  1NZL A;  3UF4 A;  1GHU A;  2L3T A;  1MIL A;  3EAZ A;  5EEL A;  3WA4 A;  3GXX A;  4K2R A;  1FHS A;  1H9O A;  1IS0 A;  2CS0 A;  2RVF A;  2Y3A B;  3S9K A;  1A07 A;  4FL2 A;  4K45 A;  3QWX X;  2JYQ A;  5DC9 A;  1O4I A;  4A4B A;  4OHI A;  1BF5 A;  1O4O A;  1BHH A;  2C0T A;  1D4T A;  2HCK A;  3HIZ B;  2IZV A;  1O4A A;  1Y1U A;  2GSB A;  4GPL B;  1AYA A;  1O46 A;  1FYR A;  3CBL A;  1GRI A;  2CBL A;  1LKK A;  3MXY A;  1OO3 A;  2PLE A;  5AXI A;  1O47 A;  1KA6 A;  1O45 A;  1O4D A;  5BO4 A;  4LUD A;  3HHM B;  1O4F A;  1LCK A;  2YSX A;  2HDV A;  1O48 A;  2HUW A;  1WQU A;  1JYU A;  2XP1 A;  1SPR A;  1A1A A;  2CR4 A;  4P9Z A;  2LQN A;  1AOT F;  3C7I A;  3IMD A;  3OV1 A;  4GL9 E;  1O4P A;  1SHB A;  1LKL A;  3TL0 A;  1RQQ C;  1QCF A;  1BLJ A;  3KFJ A;  3MAZ A;  3BUX B;  2K7A B;  3IMJ A;  1AB2 A;  2ROR A;  4EY0 A;  2SRC A;  2IUI A;  1LUM A;  1JYQ A;  1FU6 A;  2DCR A;  1BFJ A;  2DLY A;  1O4E A;  4D8K A;  2B3O A;  3BUN B;  4F59 A;  2MK2 A;  1MW4 A;  2ETZ A;  5GJH A;  3VS3 A;  1O4G A;  4U17 A;  3VS4 A;  1R1Q A;  2PTK A;  2MC1 A;  4P9V A;  4F5B A;  2LNW A;  1Z3K A;  4OHE A;  3GXW A;  3NHN A;  3VRY A;  1FMK A;  2IUG A;  4L1B B;  2MQI A;  3US4 A;  2KK6 A;  3CWG A;  5AUL A;  1AYB A;  2DLZ A;  2EO6 A;  1AYC A;  3BUO B;  1P13 A;  2Y1M A;  3OVE A;  1O4K A;  2DX0 A;  2Y1N A;  5GJI A;  3BUW B;  2EYZ A;  2AOB A;  4E68 A;  1O4L A;  3ZNI A;  1PIC A;  4JEG A;  4OHH A;  2AUG A;  1FU5 A;  1UUS A;  1O4M A;  3EAC A;  4K44 A;  1A1B A;  5DF6 A;  2PLD A;  1JU5 A;  1SHA A;  2FO0 A;  3S8L A;  3VRQ A;  1BKL A;  2OZO A;  5IBS A;  2GE9 A;  3VRO A;  1M27 A;  5HKZ A;  5EG3 B;  2MRK A;  2EO3 A;  5I6V A;  2RMX A;  1HCT B;  3VRP A;  3PLF B;  1BFI A;  3VGO A;  3BKB A;  5D0J A;  1YVH A;  4TZI A;  2H8H A;  1KSW A;  1BLK A;  1JYR A;  1OPK A;  2HMH A;  4DGP A;  5J3X A;  4JGH A;  4WWQ A;  2MRJ A;  1A08 A;  3IN8 A;  4JE4 A;  1A1C A;  3CD3 A;  1O49 A;  3N8M A;  3VS1 A;  4ROJ A;  1BM2 A;  4H1O A;  4XZ1 A;  1K9A A;  2QMS A;  3OB1 B;  3M7F A;  3S8N A;  1CWD L;  1JWO A;  3K2M A;  2L4K A;  5KAZ A;  3OB2 B;  2EL8 A;  3QWY A;  1X6C A;  4X6S A;  2RSY A;  1FBZ A;  1UUR A;  4K11 A;  1OPL A;  1SKJ A;  1LCJ A;  3PSK A;  1O4N A;  1ZFP E;  2YU7 A;  1O42 A;  1YVL A;  1O4J A;  3PFV A;  1TCE A;  1RJA A;  2DVJ A;  2BBU A;  2EYY A;  4E93 A;  2C9W A;  2VIF A;  3S8O A;  1LUN A;  1CSY A;  1BHF A;  2HDX A;  2EOB A;  1CSZ A;  1IJR A;  5EHR A;  1RPY A;  2CRH A;  1AYD A;  4QSY A;  2EU0 A;  3VRR A;  2CI8 A;  1O41 A;  4H34 A;  2LQW A;  4XZ0 A;  3VRN A;  4OHL A;  2L6K A;  1A81 A;  1R1P A;  1O4H A;  4GWF A;  1O4Q A;  1R1S A;  1O4C A;  3UYO A;  2ECD A;  4DGX A;  2DM0 A;  2EKX A;  2KNO A;  3CXL A;  1CWE A;  3PS5 A;  5EEQ A;  1O4R A;  3VRZ A;  1O43 A;  2PNA A;  1LUK A;  5EHP A;  2OQ1 A;  4FL3 A;  4A4C A;  3N7Y A;  2K79 B; 
#chains in the Genus database with same CATH topology
 1D4W A;  1QG1 E;  1BHH B;  3VS6 A;  4EIH A;  1LUI A;  1AD5 A;  2FCI A;  1OO4 A;  1G83 A;  1CJ1 A;  2H46 E;  1XA6 A;  2AOA A;  2C0O A;  4NWF A;  3VS2 A;  1BG1 A;  4FBN A;  2LNX A;  5CDW A;  1HCS B;  3HCK A;  1FBV A;  3TKZ A;  3PQZ A;  2LRA A;  3BUM B;  1NZV A;  1O44 A;  1TZE E;  5DC4 A;  1SHD A;  1Y57 A;  1F1W A;  1QAD A;  1A1E A;  2ABL A;  2CI9 A;  2EYV A;  2PNB A;  5HKW A;  4LUE A;  4M4Z A;  2CIA A;  3GQI B;  3VS7 A;  3VS5 A;  5DC0 B;  2KGY A;  3PJP A;  3N84 A;  1A09 A;  1X0N A;  3OP0 A;  3K2T A;  1X27 A;  2LCT A;  1F2F A;  3PSJ A;  1SPS A;  3IN7 A;  5HKY A;  3T04 A;  4U1P A;  5IBM A;  1AOU F;  1KC2 A;  2H5K A;  1O4B A;  1M61 A;  1BMB A;  1I3Z A;  3MXC A;  1NRV A;  4NWG A;  2SHP A;  4F5A A;  2C0I A;  3VS0 A;  1KA7 A;  1D1Z A;  2IUH A;  1B47 A;  1BKM A;  4OHD A;  1NZL A;  3UF4 A;  1GHU A;  2L3T A;  1MIL A;  3EAZ A;  5EEL A;  3WA4 A;  3GXX A;  4K2R A;  1FHS A;  1H9O A;  1IS0 A;  2CS0 A;  2RVF A;  2Y3A B;  3S9K A;  1A07 A;  4FL2 A;  4K45 A;  3QWX X;  2JYQ A;  5DC9 A;  1O4I A;  4A4B A;  4OHI A;  1BF5 A;  1O4O A;  1BHH A;  2C0T A;  1D4T A;  2HCK A;  3HIZ B;  2IZV A;  1O4A A;  1Y1U A;  2GSB A;  4GPL B;  1AYA A;  1O46 A;  1FYR A;  3CBL A;  1GRI A;  2CBL A;  1LKK A;  3MXY A;  1OO3 A;  2PLE A;  5AXI A;  1O47 A;  1KA6 A;  1O45 A;  1O4D A;  5BO4 A;  4LUD A;  3HHM B;  1O4F A;  3LYV A;  1LCK A;  2YSX A;  2HDV A;  1O48 A;  2HUW A;  1WQU A;  1JYU A;  2XP1 A;  1SPR A;  1A1A A;  2CR4 A;  4P9Z A;  2LQN A;  1AOT F;  3C7I A;  3IMD A;  3OV1 A;  4GL9 E;  1O4P A;  1SHB A;  1LKL A;  3TL0 A;  1RQQ C;  1QCF A;  1BLJ A;  3KFJ A;  3MAZ A;  3BUX B;  2K7A B;  3IMJ A;  1AB2 A;  2ROR A;  4EY0 A;  2SRC A;  2IUI A;  1LUM A;  1JYQ A;  1FU6 A;  2DCR A;  1BFJ A;  2DLY A;  1O4E A;  4D8K A;  2B3O A;  3BUN B;  4F59 A;  2MK2 A;  1MW4 A;  2ETZ A;  5GJH A;  3VS3 A;  1O4G A;  4U17 A;  3VS4 A;  1R1Q A;  2PTK A;  2MC1 A;  4P9V A;  4F5B A;  2LNW A;  1Z3K A;  4OHE A;  3GXW A;  3NHN A;  3VRY A;  1FMK A;  2IUG A;  4L1B B;  2MQI A;  3US4 A;  2KK6 A;  3CWG A;  5AUL A;  1AYB A;  2DLZ A;  2EO6 A;  1AYC A;  3BUO B;  1P13 A;  2Y1M A;  3OVE A;  1O4K A;  2DX0 A;  2Y1N A;  5GJI A;  3BUW B;  2EYZ A;  2AOB A;  4E68 A;  1O4L A;  3ZNI A;  1PIC A;  4JEG A;  4OHH A;  2AUG A;  1FU5 A;  1UUS A;  1O4M A;  3EAC A;  4K44 A;  1A1B A;  5DF6 A;  2PLD A;  1JU5 A;  1SHA A;  2FO0 A;  3S8L A;  3VRQ A;  1BKL A;  2OZO A;  5IBS A;  2GE9 A;  3VRO A;  1M27 A;  5HKZ A;  5EG3 B;  2MRK A;  2EO3 A;  5I6V A;  2RMX A;  1HCT B;  3VRP A;  3PLF B;  1BFI A;  3VGO A;  3BKB A;  5D0J A;  1YVH A;  4TZI A;  2H8H A;  1KSW A;  1BLK A;  1JYR A;  1OPK A;  2HMH A;  4DGP A;  5J3X A;  4JGH A;  4WWQ A;  2MRJ A;  1A08 A;  3IN8 A;  4JE4 A;  1A1C A;  3CD3 A;  1O49 A;  3N8M A;  3VS1 A;  4ROJ A;  1BM2 A;  4H1O A;  4XZ1 A;  1K9A A;  2QMS A;  3OB1 B;  3M7F A;  3S8N A;  1CWD L;  1JWO A;  3K2M A;  2L4K A;  5KAZ A;  3OB2 B;  2EL8 A;  3QWY A;  1X6C A;  4X6S A;  2RSY A;  1FBZ A;  1UUR A;  4K11 A;  1OPL A;  1SKJ A;  1LCJ A;  3PSK A;  1O4N A;  1ZFP E;  2YU7 A;  1O42 A;  1YVL A;  1O4J A;  3PFV A;  1TCE A;  1RJA A;  2DVJ A;  2BBU A;  2EYY A;  4E93 A;  2C9W A;  2VIF A;  3S8O A;  1LUN A;  1CSY A;  1BHF A;  2HDX A;  2EOB A;  1CSZ A;  1IJR A;  5EHR A;  1RPY A;  2CRH A;  1AYD A;  4QSY A;  2EU0 A;  3VRR A;  2CI8 A;  1O41 A;  4H34 A;  2LQW A;  4XZ0 A;  3VRN A;  4OHL A;  2L6K A;  1A81 A;  1R1P A;  1O4H A;  4GWF A;  1O4Q A;  1R1S A;  1O4C A;  3UYO A;  2ECD A;  4DGX A;  2DM0 A;  2EKX A;  2KNO A;  3CXL A;  1CWE A;  3PS5 A;  5EEQ A;  1O4R A;  3VRZ A;  1O43 A;  2PNA A;  1LUK A;  5EHP A;  2OQ1 A;  4FL3 A;  4A4C A;  3N7Y A;  2K79 B; 
#chains in the Genus database with same CATH homology
 1D4W A;  1QG1 E;  1BHH B;  3VS6 A;  4EIH A;  1LUI A;  1AD5 A;  2FCI A;  1OO4 A;  1G83 A;  1CJ1 A;  2H46 E;  1XA6 A;  2AOA A;  2C0O A;  4NWF A;  3VS2 A;  1BG1 A;  4FBN A;  2LNX A;  5CDW A;  1HCS B;  3HCK A;  1FBV A;  3TKZ A;  3PQZ A;  3BUM B;  1NZV A;  1O44 A;  1TZE E;  5DC4 A;  1SHD A;  1Y57 A;  1F1W A;  1QAD A;  1A1E A;  2ABL A;  2CI9 A;  2EYV A;  2PNB A;  5HKW A;  4LUE A;  4M4Z A;  2CIA A;  3GQI B;  3VS7 A;  3VS5 A;  5DC0 B;  3PJP A;  3N84 A;  1A09 A;  1X0N A;  3OP0 A;  1X27 A;  2LCT A;  1F2F A;  3PSJ A;  1SPS A;  3IN7 A;  5HKY A;  3T04 A;  4U1P A;  5IBM A;  1AOU F;  1KC2 A;  2H5K A;  1O4B A;  1M61 A;  1BMB A;  1I3Z A;  3MXC A;  1NRV A;  4NWG A;  2SHP A;  4F5A A;  2C0I A;  3VS0 A;  1KA7 A;  1D1Z A;  2IUH A;  1B47 A;  1BKM A;  4OHD A;  1NZL A;  3UF4 A;  1GHU A;  2L3T A;  1MIL A;  3EAZ A;  5EEL A;  3WA4 A;  3GXX A;  4K2R A;  1FHS A;  1H9O A;  1IS0 A;  2CS0 A;  2RVF A;  2Y3A B;  3S9K A;  1A07 A;  4FL2 A;  4K45 A;  3QWX X;  2JYQ A;  5DC9 A;  1O4I A;  4A4B A;  4OHI A;  1BF5 A;  1O4O A;  1BHH A;  2C0T A;  1D4T A;  2HCK A;  3HIZ B;  2IZV A;  1O4A A;  1Y1U A;  2GSB A;  4GPL B;  1AYA A;  1O46 A;  1FYR A;  3CBL A;  1GRI A;  2CBL A;  1LKK A;  3MXY A;  1OO3 A;  2PLE A;  5AXI A;  1O47 A;  1KA6 A;  1O45 A;  1O4D A;  5BO4 A;  4LUD A;  3HHM B;  1O4F A;  1LCK A;  2YSX A;  2HDV A;  1O48 A;  2HUW A;  1WQU A;  1JYU A;  2XP1 A;  1SPR A;  1A1A A;  2CR4 A;  4P9Z A;  2LQN A;  1AOT F;  3C7I A;  3IMD A;  3OV1 A;  4GL9 E;  1O4P A;  1SHB A;  1LKL A;  3TL0 A;  1RQQ C;  1QCF A;  1BLJ A;  3KFJ A;  3MAZ A;  3BUX B;  2K7A B;  3IMJ A;  1AB2 A;  2ROR A;  4EY0 A;  2SRC A;  2IUI A;  1LUM A;  1JYQ A;  1FU6 A;  2DCR A;  1BFJ A;  2DLY A;  1O4E A;  4D8K A;  2B3O A;  3BUN B;  4F59 A;  2MK2 A;  1MW4 A;  2ETZ A;  5GJH A;  3VS3 A;  1O4G A;  4U17 A;  3VS4 A;  1R1Q A;  2PTK A;  2MC1 A;  4P9V A;  4F5B A;  2LNW A;  1Z3K A;  4OHE A;  3GXW A;  3NHN A;  3VRY A;  1FMK A;  2IUG A;  4L1B B;  2MQI A;  3US4 A;  2KK6 A;  3CWG A;  5AUL A;  1AYB A;  2DLZ A;  2EO6 A;  1AYC A;  3BUO B;  1P13 A;  2Y1M A;  3OVE A;  1O4K A;  2DX0 A;  2Y1N A;  5GJI A;  3BUW B;  2EYZ A;  2AOB A;  4E68 A;  1O4L A;  3ZNI A;  1PIC A;  4JEG A;  4OHH A;  2AUG A;  1FU5 A;  1UUS A;  1O4M A;  3EAC A;  4K44 A;  1A1B A;  5DF6 A;  2PLD A;  1JU5 A;  1SHA A;  2FO0 A;  3S8L A;  3VRQ A;  1BKL A;  2OZO A;  5IBS A;  2GE9 A;  3VRO A;  1M27 A;  5HKZ A;  5EG3 B;  2MRK A;  2EO3 A;  5I6V A;  2RMX A;  1HCT B;  3VRP A;  3PLF B;  1BFI A;  3VGO A;  3BKB A;  5D0J A;  1YVH A;  4TZI A;  2H8H A;  1KSW A;  1BLK A;  1JYR A;  1OPK A;  2HMH A;  4DGP A;  5J3X A;  4JGH A;  4WWQ A;  2MRJ A;  1A08 A;  3IN8 A;  4JE4 A;  1A1C A;  3CD3 A;  1O49 A;  3N8M A;  3VS1 A;  4ROJ A;  1BM2 A;  4H1O A;  4XZ1 A;  1K9A A;  2QMS A;  3OB1 B;  3M7F A;  3S8N A;  1CWD L;  1JWO A;  3K2M A;  2L4K A;  5KAZ A;  3OB2 B;  2EL8 A;  3QWY A;  1X6C A;  4X6S A;  2RSY A;  1FBZ A;  1UUR A;  4K11 A;  1OPL A;  1SKJ A;  1LCJ A;  3PSK A;  1O4N A;  1ZFP E;  2YU7 A;  1O42 A;  1YVL A;  1O4J A;  3PFV A;  1TCE A;  1RJA A;  2DVJ A;  2BBU A;  2EYY A;  4E93 A;  2C9W A;  2VIF A;  3S8O A;  1LUN A;  1CSY A;  1BHF A;  2HDX A;  2EOB A;  1CSZ A;  1IJR A;  5EHR A;  1RPY A;  2CRH A;  1AYD A;  4QSY A;  2EU0 A;  3VRR A;  2CI8 A;  1O41 A;  4H34 A;  2LQW A;  4XZ0 A;  3VRN A;  4OHL A;  2L6K A;  1A81 A;  1R1P A;  1O4H A;  4GWF A;  1O4Q A;  1R1S A;  1O4C A;  3UYO A;  2ECD A;  4DGX A;  2DM0 A;  2EKX A;  2KNO A;  3CXL A;  1CWE A;  3PS5 A;  5EEQ A;  1O4R A;  3VRZ A;  1O43 A;  2PNA A;  1LUK A;  5EHP A;  2OQ1 A;  4FL3 A;  4A4C A;  3N7Y A;  2K79 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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