1O4EA

Crystal structure of sh2 in complex with ru78299.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4eA00
3VS7A 3VRNA 1O49A 5AULA 1NRVA 3IMDA 3HHMB 4K2RA 1NZVA 4U17A 3PLFB 1OPKA 3MAZA 1LUNA 1A1BA 1AB2A 2Y1NA 4JE4A 1I3ZA 4P9ZA 1LUKA 5KAZA 2AOBA 1G83A 1KSWA 3S9KA 4OHEA 1H9OA 1O47A 3QWXX 4K11A 3TKZA 1O4LA 4GPLB 3EAZA 3N84A 2PNBA 2C0OA 2MK2A 1SHAA 4FL3A 4U1PA 1UUSA 2HUWA 1JWOA 4A4CA 2SHPA 1LCJA 2DVJA 1F2FA 5IBMA 1QCFA 4LUEA 2KNOA 1O4HA 3OV1A 1RJAA 5DC9A 5CDWA 3CWGA 5DC0B 1JYUA 2Y1MA 2GE9A 3VS0A 2IZVA 5HKZA 5EEQA 5IBSA 2DM0A 3HCKA 2EYYA 1OO3A 1LUMA 4K45A 2DX0A 1CJ1A 2CIAA 4FL2A 1IJRA 2C0IA 2CS0A 4F59A 1O48A 4X6SA 3KFJA 2QMSA 1BHFA 1B47A 1M27A 5GJIA 3VS6A 4A4BA 2RMXA 2MRKA 5J3XA 3BUWB 3GXXA 2L3TA 1WQUA 2RVFA 1Y57A 1FHSA 1O4EA 1AYCA 3S8LA 2L4KA 1O4KA 1A08A 1JU5A 3S8OA 3WA4A 2MRJA 1BKLA 3CBLA 1O4QA 2DLYA 2VIFA 4DGPA 4TZIA 2CI9A 1NZLA 1LKKA 2HDXA 2XP1A 1O4CA 1SHDA 1X0NA 1HCSB 1Z3KA 4XZ1A 2ABLA 3VS2A 1LCKA 1AYDA 1D1ZA 3EACA 1CSZA 1D4TA 3M7FA 2EL8A 1SPSA 1A07A 1KA6A 1O4GA 2H46E 1BLJA 3N7YA 2DLZA 1D4WA 2HDVA 3N8MA 3OB1B 1A81A 2K7AB 2EKXA 4DGXA 4EIHA 4WWQA 2YU7A 3VS3A 1O4JA 1GRIA 3T04A 1CSYA 4GL9E 3PQZA 2MQIA 2B3OA 3OB2B 1BKMA 1CWEA 3GQIB 1O4FA 1O4AA 2IUGA 3US4A 1AOUF 3PJPA 1BHHA 1MW4A 3VRZA 1YVHA 3IN8A 2PNAA 3C7IA 1BM2A 3BKBA 2LQNA 1BMBA 1AD5A 3PS5A 5BO4A 1KA7A 1R1PA 1BFJA 2Y3AB 3MXYA 3PSJA 1JYQA 2DCRA 2L6KA 1BHHB 5DC4A 2AOAA 4H34A 1A1AA 1O4NA 2EU0A 1QADA 1FU6A 1LKLA 2LNWA 3K2MA 3VS5A 3BUMB 5DF6A 4OHLA 2ETZA 3VRPA 4LUDA 3CXLA 1O42A 4FBNA 1CWDL 4NWGA 5AXIA 1K9AA 2FO0A 1O4DA 2EYZA 5HKWA 1HCTB 3NHNA 2EYVA 1O45A 1O43A 2BBUA 5I6VA 2CRHA 2HMHA 4NWFA 4OHHA 4D8KA 1A09A 4E68A 1A1CA 1FBZA 1M61A 1O41A 1FU5A 1SHBA 2H8HA 1O44A 1ZFPE 2HCKA 3S8NA 2LCTA 3VROA 1AYBA 1RQQC 4L1BB 1TZEE 1AOTF 2IUHA 3BUXB 5D0JA 2PLEA 2LNXA 1XA6A 4EY0A 1X6CA 2SRCA 2JYQA 5EHPA 1QG1E 3PSKA 3MXCA 5EG3B 2C0TA 4F5AA 2MC1A 4QSYA 1SKJA 1BLKA 1RPYA 1O4RA 4ROJA 1KC2A 4JGHA 2EO3A 3ZNIA 1AYAA 1LUIA 2ECDA 3CD3A 1BG1A 2OZOA 3OVEA 3VS1A 3HIZB 3UYOA 1IS0A 3TL0A 4E93A 2PTKA 3IN7A 1A1EA 2OQ1A 1O4IA 1TCEA 5GJHA 3PFVA 3UF4A 2CR4A 4H1OA 1MILA 1FBVA 3VRQA 1O4OA 1R1QA 4JEGA 2K79B 2AUGA 1O46A 1X27A 2LQWA 3QWYA 1O4PA 1JYRA 2CBLA 2CI8A 2H5KA 2C9WA 4M4ZA 3OP0A 3BUNB 1O4BA 1R1SA 4K44A 3BUOB 4OHDA 2KK6A 1OPLA 1FMKA 2IUIA 4XZ0A 5EELA 1O4MA 1F1WA 2EOBA 2YSXA 4P9VA 1BFIA 1UURA 4OHIA 3VRRA 1OO4A 2GSBA 1GHUA 1Y1UA 1P13A 1SPRA 2FCIA 1BF5A 5EHRA 1YVLA 2EO6A 3VS4A 1PICA 3VRYA 3VGOA 2RSYA 4GWFA 5HKYA 3IMJA 2RORA 1FYRA 4F5BA 3GXWA 2PLDA
chains in the Genus database with same CATH superfamily
3VS7A 3VRNA 1O49A 5AULA 1NRVA 3IMDA 3HHMB 4K2RA 1NZVA 4U17A 3PLFB 1OPKA 3MAZA 1LUNA 1A1BA 1AB2A 2Y1NA 4JE4A 1I3ZA 4P9ZA 1LUKA 5KAZA 2AOBA 1G83A 1KSWA 3S9KA 4OHEA 1H9OA 1O47A 3QWXX 4K11A 3TKZA 1O4LA 4GPLB 3EAZA 3N84A 2PNBA 2C0OA 2MK2A 1SHAA 4FL3A 4U1PA 1UUSA 2HUWA 1JWOA 4A4CA 2SHPA 1LCJA 2KGYA 2DVJA 1F2FA 5IBMA 1QCFA 4LUEA 2KNOA 1O4HA 3OV1A 1RJAA 5DC9A 5CDWA 3CWGA 5DC0B 1JYUA 2Y1MA 2GE9A 3VS0A 2IZVA 5HKZA 5EEQA 5IBSA 2DM0A 3HCKA 2EYYA 1OO3A 1LUMA 4K45A 2DX0A 1CJ1A 2CIAA 4FL2A 1IJRA 2C0IA 2CS0A 4F59A 1O48A 4X6SA 3KFJA 2QMSA 1BHFA 1B47A 1M27A 5GJIA 3VS6A 4A4BA 2RMXA 2MRKA 5J3XA 3BUWB 3GXXA 2L3TA 1WQUA 2RVFA 1Y57A 1FHSA 1O4EA 1AYCA 3S8LA 2L4KA 1O4KA 1A08A 1JU5A 3S8OA 3WA4A 2MRJA 1BKLA 3CBLA 1O4QA 2DLYA 2VIFA 4DGPA 4TZIA 2CI9A 1NZLA 1LKKA 3LYVA 2HDXA 2XP1A 1O4CA 1SHDA 1X0NA 1HCSB 1Z3KA 4XZ1A 3K2TA 2ABLA 3VS2A 1LCKA 1AYDA 1D1ZA 3EACA 1CSZA 1D4TA 3M7FA 2EL8A 1SPSA 1A07A 1KA6A 1O4GA 2H46E 1BLJA 3N7YA 2DLZA 1D4WA 2HDVA 3N8MA 2LRAA 3OB1B 1A81A 2K7AB 2EKXA 4DGXA 4EIHA 4WWQA 2YU7A 3VS3A 1O4JA 1GRIA 3T04A 1CSYA 4GL9E 3PQZA 2MQIA 2B3OA 3OB2B 1BKMA 1CWEA 3GQIB 1O4FA 1O4AA 2IUGA 3US4A 1AOUF 3PJPA 1BHHA 1MW4A 3VRZA 1YVHA 3IN8A 2PNAA 3C7IA 1BM2A 3BKBA 2LQNA 1BMBA 1AD5A 3PS5A 5BO4A 1KA7A 1R1PA 1BFJA 2Y3AB 3MXYA 3PSJA 1JYQA 2DCRA 2L6KA 1BHHB 5DC4A 2AOAA 4H34A 1A1AA 1O4NA 2EU0A 1QADA 1FU6A 1LKLA 2LNWA 3K2MA 3VS5A 3BUMB 5DF6A 4OHLA 2ETZA 3VRPA 4LUDA 3CXLA 1O42A 4FBNA 1CWDL 4NWGA 5AXIA 1K9AA 2FO0A 1O4DA 2EYZA 5HKWA 1HCTB 3NHNA 2EYVA 1O45A 1O43A 2BBUA 5I6VA 2CRHA 2HMHA 4NWFA 4OHHA 4D8KA 1A09A 4E68A 1A1CA 1FBZA 1M61A 1O41A 1FU5A 1SHBA 2H8HA 1O44A 1ZFPE 2HCKA 3S8NA 2LCTA 3VROA 1AYBA 1RQQC 4L1BB 1TZEE 1AOTF 2IUHA 3BUXB 5D0JA 2PLEA 2LNXA 1XA6A 4EY0A 1X6CA 2SRCA 2JYQA 5EHPA 1QG1E 3PSKA 3MXCA 5EG3B 2C0TA 4F5AA 2MC1A 4QSYA 1SKJA 1BLKA 1RPYA 1O4RA 4ROJA 1KC2A 4JGHA 2EO3A 3ZNIA 1AYAA 1LUIA 2ECDA 3CD3A 1BG1A 2OZOA 3OVEA 3VS1A 3HIZB 3UYOA 1IS0A 3TL0A 4E93A 2PTKA 3IN7A 1A1EA 2OQ1A 1O4IA 1TCEA 5GJHA 3PFVA 3UF4A 2CR4A 4H1OA 1MILA 1FBVA 3VRQA 1O4OA 1R1QA 4JEGA 2K79B 2AUGA 1O46A 1X27A 2LQWA 3QWYA 1O4PA 1JYRA 2CBLA 2CI8A 2H5KA 2C9WA 4M4ZA 3OP0A 3BUNB 1O4BA 1R1SA 4K44A 3BUOB 4OHDA 2KK6A 1OPLA 1FMKA 2IUIA 4XZ0A 5EELA 1O4MA 1F1WA 2EOBA 2YSXA 4P9VA 1BFIA 1UURA 4OHIA 3VRRA 1OO4A 2GSBA 1GHUA 1Y1UA 1P13A 1SPRA 2FCIA 1BF5A 5EHRA 1YVLA 2EO6A 3VS4A 1PICA 3VRYA 3VGOA 2RSYA 4GWFA 5HKYA 3IMJA 2RORA 1FYRA 4F5BA 3GXWA 2PLDA
chains in the Genus database with same CATH topology
3VS7A 3VRNA 1O49A 5AULA 1NRVA 3IMDA 3HHMB 4K2RA 1NZVA 4U17A 3PLFB 1OPKA 3MAZA 1LUNA 1A1BA 1AB2A 2Y1NA 4JE4A 1I3ZA 4P9ZA 1LUKA 5KAZA 2AOBA 1G83A 1KSWA 3S9KA 4OHEA 1H9OA 1O47A 3QWXX 4K11A 3TKZA 1O4LA 4GPLB 3EAZA 3N84A 2PNBA 2C0OA 2MK2A 1SHAA 4FL3A 4U1PA 1UUSA 2HUWA 1JWOA 4A4CA 2SHPA 1LCJA 2DVJA 1F2FA 5IBMA 1QCFA 4LUEA 2KNOA 1O4HA 3OV1A 1RJAA 5DC9A 5CDWA 3CWGA 5DC0B 1JYUA 2Y1MA 2GE9A 3VS0A 2IZVA 5HKZA 5EEQA 5IBSA 2DM0A 3HCKA 2EYYA 1OO3A 1LUMA 4K45A 2DX0A 1CJ1A 2CIAA 4FL2A 1IJRA 2C0IA 2CS0A 4F59A 1O48A 4X6SA 3KFJA 2QMSA 1BHFA 1B47A 1M27A 5GJIA 3VS6A 4A4BA 2RMXA 2MRKA 5J3XA 3BUWB 3GXXA 2L3TA 1WQUA 2RVFA 1Y57A 1FHSA 1O4EA 1AYCA 3S8LA 2L4KA 1O4KA 1A08A 1JU5A 3S8OA 3WA4A 2MRJA 1BKLA 3CBLA 1O4QA 2DLYA 2VIFA 4DGPA 4TZIA 2CI9A 1NZLA 1LKKA 2HDXA 2XP1A 1O4CA 1SHDA 1X0NA 1HCSB 1Z3KA 4XZ1A 2ABLA 3VS2A 1LCKA 1AYDA 1D1ZA 3EACA 1CSZA 1D4TA 3M7FA 2EL8A 1SPSA 1A07A 1KA6A 1O4GA 2H46E 1BLJA 3N7YA 2DLZA 1D4WA 2HDVA 3N8MA 3OB1B 1A81A 2K7AB 2EKXA 4DGXA 4EIHA 4WWQA 2YU7A 3VS3A 1O4JA 1GRIA 3T04A 1CSYA 4GL9E 3PQZA 2MQIA 2B3OA 3OB2B 1BKMA 1CWEA 3GQIB 1O4FA 1O4AA 2IUGA 3US4A 1AOUF 3PJPA 1BHHA 1MW4A 3VRZA 1YVHA 3IN8A 2PNAA 3C7IA 1BM2A 3BKBA 2LQNA 1BMBA 1AD5A 3PS5A 5BO4A 1KA7A 1R1PA 1BFJA 2Y3AB 3MXYA 3PSJA 1JYQA 2DCRA 2L6KA 1BHHB 5DC4A 2AOAA 4H34A 1A1AA 1O4NA 2EU0A 1QADA 1FU6A 1LKLA 2LNWA 3K2MA 3VS5A 3BUMB 5DF6A 4OHLA 2ETZA 3VRPA 4LUDA 3CXLA 1O42A 4FBNA 1CWDL 4NWGA 5AXIA 1K9AA 2FO0A 1O4DA 2EYZA 5HKWA 1HCTB 3NHNA 2EYVA 1O45A 1O43A 2BBUA 5I6VA 2CRHA 2HMHA 4NWFA 4OHHA 4D8KA 1A09A 4E68A 1A1CA 1FBZA 1M61A 1O41A 1FU5A 1SHBA 2H8HA 1O44A 1ZFPE 2HCKA 3S8NA 2LCTA 3VROA 1AYBA 1RQQC 4L1BB 1TZEE 1AOTF 2IUHA 3BUXB 5D0JA 2PLEA 2LNXA 1XA6A 4EY0A 1X6CA 2SRCA 2JYQA 5EHPA 1QG1E 3PSKA 3MXCA 5EG3B 2C0TA 4F5AA 2MC1A 4QSYA 1SKJA 1BLKA 1RPYA 1O4RA 4ROJA 1KC2A 4JGHA 2EO3A 3ZNIA 1AYAA 1LUIA 2ECDA 3CD3A 1BG1A 2OZOA 3OVEA 3VS1A 3HIZB 3UYOA 1IS0A 3TL0A 4E93A 2PTKA 3IN7A 1A1EA 2OQ1A 1O4IA 1TCEA 5GJHA 3PFVA 3UF4A 2CR4A 4H1OA 1MILA 1FBVA 3VRQA 1O4OA 1R1QA 4JEGA 2K79B 2AUGA 1O46A 1X27A 2LQWA 3QWYA 1O4PA 1JYRA 2CBLA 2CI8A 2H5KA 2C9WA 4M4ZA 3OP0A 3BUNB 1O4BA 1R1SA 4K44A 3BUOB 4OHDA 2KK6A 1OPLA 1FMKA 2IUIA 4XZ0A 5EELA 1O4MA 1F1WA 2EOBA 2YSXA 4P9VA 1BFIA 1UURA 4OHIA 3VRRA 1OO4A 2GSBA 1GHUA 1Y1UA 1P13A 1SPRA 2FCIA 1BF5A 5EHRA 1YVLA 2EO6A 3VS4A 1PICA 3VRYA 3VGOA 2RSYA 4GWFA 5HKYA 3IMJA 2RORA 1FYRA 4F5BA 3GXWA 2PLDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VS7 A;  3VRN A;  1O49 A;  5AUL A;  1NRV A;  3IMD A;  3HHM B;  4K2R A;  1NZV A;  4U17 A;  3PLF B;  1OPK A;  3MAZ A;  1LUN A;  1A1B A;  1AB2 A;  2Y1N A;  4JE4 A;  1I3Z A;  4P9Z A;  1LUK A;  5KAZ A;  2AOB A;  1G83 A;  1KSW A;  3S9K A;  4OHE A;  1H9O A;  1O47 A;  3QWX X;  4K11 A;  3TKZ A;  1O4L A;  4GPL B;  3EAZ A;  3N84 A;  2PNB A;  2C0O A;  2MK2 A;  1SHA A;  4FL3 A;  4U1P A;  1UUS A;  2HUW A;  1JWO A;  4A4C A;  2SHP A;  1LCJ A;  2DVJ A;  1F2F A;  5IBM A;  1QCF A;  4LUE A;  2KNO A;  1O4H A;  3OV1 A;  1RJA A;  5DC9 A;  5CDW A;  3CWG A;  5DC0 B;  1JYU A;  2Y1M A;  2GE9 A;  3VS0 A;  2IZV A;  5HKZ A;  5EEQ A;  5IBS A;  2DM0 A;  3HCK A;  2EYY A;  1OO3 A;  1LUM A;  4K45 A;  2DX0 A;  1CJ1 A;  2CIA A;  4FL2 A;  1IJR A;  2C0I A;  2CS0 A;  4F59 A;  1O48 A;  4X6S A;  3KFJ A;  2QMS A;  1BHF A;  1B47 A;  1M27 A;  5GJI A;  3VS6 A;  4A4B A;  2RMX A;  2MRK A;  5J3X A;  3BUW B;  3GXX A;  2L3T A;  1WQU A;  2RVF A;  1Y57 A;  1FHS A;  1O4E A;  1AYC A;  3S8L A;  2L4K A;  1O4K A;  1A08 A;  1JU5 A;  3S8O A;  3WA4 A;  2MRJ A;  1BKL A;  3CBL A;  1O4Q A;  2DLY A;  2VIF A;  4DGP A;  4TZI A;  2CI9 A;  1NZL A;  1LKK A;  2HDX A;  2XP1 A;  1O4C A;  1SHD A;  1X0N A;  1HCS B;  1Z3K A;  4XZ1 A;  2ABL A;  3VS2 A;  1LCK A;  1AYD A;  1D1Z A;  3EAC A;  1CSZ A;  1D4T A;  3M7F A;  2EL8 A;  1SPS A;  1A07 A;  1KA6 A;  1O4G A;  2H46 E;  1BLJ A;  3N7Y A;  2DLZ A;  1D4W A;  2HDV A;  3N8M A;  3OB1 B;  1A81 A;  2K7A B;  2EKX A;  4DGX A;  4EIH A;  4WWQ A;  2YU7 A;  3VS3 A;  1O4J A;  1GRI A;  3T04 A;  1CSY A;  4GL9 E;  3PQZ A;  2MQI A;  2B3O A;  3OB2 B;  1BKM A;  1CWE A;  3GQI B;  1O4F A;  1O4A A;  2IUG A;  3US4 A;  1AOU F;  3PJP A;  1BHH A;  1MW4 A;  3VRZ A;  1YVH A;  3IN8 A;  2PNA A;  3C7I A;  1BM2 A;  3BKB A;  2LQN A;  1BMB A;  1AD5 A;  3PS5 A;  5BO4 A;  1KA7 A;  1R1P A;  1BFJ A;  2Y3A B;  3MXY A;  3PSJ A;  1JYQ A;  2DCR A;  2L6K A;  1BHH B;  5DC4 A;  2AOA A;  4H34 A;  1A1A A;  1O4N A;  2EU0 A;  1QAD A;  1FU6 A;  1LKL A;  2LNW A;  3K2M A;  3VS5 A;  3BUM B;  5DF6 A;  4OHL A;  2ETZ A;  3VRP A;  4LUD A;  3CXL A;  1O42 A;  4FBN A;  1CWD L;  4NWG A;  5AXI A;  1K9A A;  2FO0 A;  1O4D A;  2EYZ A;  5HKW A;  1HCT B;  3NHN A;  2EYV A;  1O45 A;  1O43 A;  2BBU A;  5I6V A;  2CRH A;  2HMH A;  4NWF A;  4OHH A;  4D8K A;  1A09 A;  4E68 A;  1A1C A;  1FBZ A;  1M61 A;  1O41 A;  1FU5 A;  1SHB A;  2H8H A;  1O44 A;  1ZFP E;  2HCK A;  3S8N A;  2LCT A;  3VRO A;  1AYB A;  1RQQ C;  4L1B B;  1TZE E;  1AOT F;  2IUH A;  3BUX B;  5D0J A;  2PLE A;  2LNX A;  1XA6 A;  4EY0 A;  1X6C A;  2SRC A;  2JYQ A;  5EHP A;  1QG1 E;  3PSK A;  3MXC A;  5EG3 B;  2C0T A;  4F5A A;  2MC1 A;  4QSY A;  1SKJ A;  1BLK A;  1RPY A;  1O4R A;  4ROJ A;  1KC2 A;  4JGH A;  2EO3 A;  3ZNI A;  1AYA A;  1LUI A;  2ECD A;  3CD3 A;  1BG1 A;  2OZO A;  3OVE A;  3VS1 A;  3HIZ B;  3UYO A;  1IS0 A;  3TL0 A;  4E93 A;  2PTK A;  3IN7 A;  1A1E A;  2OQ1 A;  1O4I A;  1TCE A;  5GJH A;  3PFV A;  3UF4 A;  2CR4 A;  4H1O A;  1MIL A;  1FBV A;  3VRQ A;  1O4O A;  1R1Q A;  4JEG A;  2K79 B;  2AUG A;  1O46 A;  1X27 A;  2LQW A;  3QWY A;  1O4P A;  1JYR A;  2CBL A;  2CI8 A;  2H5K A;  2C9W A;  4M4Z A;  3OP0 A;  3BUN B;  1O4B A;  1R1S A;  4K44 A;  3BUO B;  4OHD A;  2KK6 A;  1OPL A;  1FMK A;  2IUI A;  4XZ0 A;  5EEL A;  1O4M A;  1F1W A;  2EOB A;  2YSX A;  4P9V A;  1BFI A;  1UUR A;  4OHI A;  3VRR A;  1OO4 A;  2GSB A;  1GHU A;  1Y1U A;  1P13 A;  1SPR A;  2FCI A;  1BF5 A;  5EHR A;  1YVL A;  2EO6 A;  3VS4 A;  1PIC A;  3VRY A;  3VGO A;  2RSY A;  4GWF A;  5HKY A;  3IMJ A;  2ROR A;  1FYR A;  4F5B A;  3GXW A;  2PLD A; 
#chains in the Genus database with same CATH topology
 3VS7 A;  3VRN A;  1O49 A;  5AUL A;  1NRV A;  3IMD A;  3HHM B;  4K2R A;  1NZV A;  4U17 A;  3PLF B;  1OPK A;  3MAZ A;  1LUN A;  1A1B A;  1AB2 A;  2Y1N A;  4JE4 A;  1I3Z A;  4P9Z A;  1LUK A;  5KAZ A;  2AOB A;  1G83 A;  1KSW A;  3S9K A;  4OHE A;  1H9O A;  1O47 A;  3QWX X;  4K11 A;  3TKZ A;  1O4L A;  4GPL B;  3EAZ A;  3N84 A;  2PNB A;  2C0O A;  2MK2 A;  1SHA A;  4FL3 A;  4U1P A;  1UUS A;  2HUW A;  1JWO A;  4A4C A;  2SHP A;  1LCJ A;  2KGY A;  2DVJ A;  1F2F A;  5IBM A;  1QCF A;  4LUE A;  2KNO A;  1O4H A;  3OV1 A;  1RJA A;  5DC9 A;  5CDW A;  3CWG A;  5DC0 B;  1JYU A;  2Y1M A;  2GE9 A;  3VS0 A;  2IZV A;  5HKZ A;  5EEQ A;  5IBS A;  2DM0 A;  3HCK A;  2EYY A;  1OO3 A;  1LUM A;  4K45 A;  2DX0 A;  1CJ1 A;  2CIA A;  4FL2 A;  1IJR A;  2C0I A;  2CS0 A;  4F59 A;  1O48 A;  4X6S A;  3KFJ A;  2QMS A;  1BHF A;  1B47 A;  1M27 A;  5GJI A;  3VS6 A;  4A4B A;  2RMX A;  2MRK A;  5J3X A;  3BUW B;  3GXX A;  2L3T A;  1WQU A;  2RVF A;  1Y57 A;  1FHS A;  1O4E A;  1AYC A;  3S8L A;  2L4K A;  1O4K A;  1A08 A;  1JU5 A;  3S8O A;  3WA4 A;  2MRJ A;  1BKL A;  3CBL A;  1O4Q A;  2DLY A;  2VIF A;  4DGP A;  4TZI A;  2CI9 A;  1NZL A;  1LKK A;  3LYV A;  2HDX A;  2XP1 A;  1O4C A;  1SHD A;  1X0N A;  1HCS B;  1Z3K A;  4XZ1 A;  3K2T A;  2ABL A;  3VS2 A;  1LCK A;  1AYD A;  1D1Z A;  3EAC A;  1CSZ A;  1D4T A;  3M7F A;  2EL8 A;  1SPS A;  1A07 A;  1KA6 A;  1O4G A;  2H46 E;  1BLJ A;  3N7Y A;  2DLZ A;  1D4W A;  2HDV A;  3N8M A;  2LRA A;  3OB1 B;  1A81 A;  2K7A B;  2EKX A;  4DGX A;  4EIH A;  4WWQ A;  2YU7 A;  3VS3 A;  1O4J A;  1GRI A;  3T04 A;  1CSY A;  4GL9 E;  3PQZ A;  2MQI A;  2B3O A;  3OB2 B;  1BKM A;  1CWE A;  3GQI B;  1O4F A;  1O4A A;  2IUG A;  3US4 A;  1AOU F;  3PJP A;  1BHH A;  1MW4 A;  3VRZ A;  1YVH A;  3IN8 A;  2PNA A;  3C7I A;  1BM2 A;  3BKB A;  2LQN A;  1BMB A;  1AD5 A;  3PS5 A;  5BO4 A;  1KA7 A;  1R1P A;  1BFJ A;  2Y3A B;  3MXY A;  3PSJ A;  1JYQ A;  2DCR A;  2L6K A;  1BHH B;  5DC4 A;  2AOA A;  4H34 A;  1A1A A;  1O4N A;  2EU0 A;  1QAD A;  1FU6 A;  1LKL A;  2LNW A;  3K2M A;  3VS5 A;  3BUM B;  5DF6 A;  4OHL A;  2ETZ A;  3VRP A;  4LUD A;  3CXL A;  1O42 A;  4FBN A;  1CWD L;  4NWG A;  5AXI A;  1K9A A;  2FO0 A;  1O4D A;  2EYZ A;  5HKW A;  1HCT B;  3NHN A;  2EYV A;  1O45 A;  1O43 A;  2BBU A;  5I6V A;  2CRH A;  2HMH A;  4NWF A;  4OHH A;  4D8K A;  1A09 A;  4E68 A;  1A1C A;  1FBZ A;  1M61 A;  1O41 A;  1FU5 A;  1SHB A;  2H8H A;  1O44 A;  1ZFP E;  2HCK A;  3S8N A;  2LCT A;  3VRO A;  1AYB A;  1RQQ C;  4L1B B;  1TZE E;  1AOT F;  2IUH A;  3BUX B;  5D0J A;  2PLE A;  2LNX A;  1XA6 A;  4EY0 A;  1X6C A;  2SRC A;  2JYQ A;  5EHP A;  1QG1 E;  3PSK A;  3MXC A;  5EG3 B;  2C0T A;  4F5A A;  2MC1 A;  4QSY A;  1SKJ A;  1BLK A;  1RPY A;  1O4R A;  4ROJ A;  1KC2 A;  4JGH A;  2EO3 A;  3ZNI A;  1AYA A;  1LUI A;  2ECD A;  3CD3 A;  1BG1 A;  2OZO A;  3OVE A;  3VS1 A;  3HIZ B;  3UYO A;  1IS0 A;  3TL0 A;  4E93 A;  2PTK A;  3IN7 A;  1A1E A;  2OQ1 A;  1O4I A;  1TCE A;  5GJH A;  3PFV A;  3UF4 A;  2CR4 A;  4H1O A;  1MIL A;  1FBV A;  3VRQ A;  1O4O A;  1R1Q A;  4JEG A;  2K79 B;  2AUG A;  1O46 A;  1X27 A;  2LQW A;  3QWY A;  1O4P A;  1JYR A;  2CBL A;  2CI8 A;  2H5K A;  2C9W A;  4M4Z A;  3OP0 A;  3BUN B;  1O4B A;  1R1S A;  4K44 A;  3BUO B;  4OHD A;  2KK6 A;  1OPL A;  1FMK A;  2IUI A;  4XZ0 A;  5EEL A;  1O4M A;  1F1W A;  2EOB A;  2YSX A;  4P9V A;  1BFI A;  1UUR A;  4OHI A;  3VRR A;  1OO4 A;  2GSB A;  1GHU A;  1Y1U A;  1P13 A;  1SPR A;  2FCI A;  1BF5 A;  5EHR A;  1YVL A;  2EO6 A;  3VS4 A;  1PIC A;  3VRY A;  3VGO A;  2RSY A;  4GWF A;  5HKY A;  3IMJ A;  2ROR A;  1FYR A;  4F5B A;  3GXW A;  2PLD A; 
#chains in the Genus database with same CATH homology
 3VS7 A;  3VRN A;  1O49 A;  5AUL A;  1NRV A;  3IMD A;  3HHM B;  4K2R A;  1NZV A;  4U17 A;  3PLF B;  1OPK A;  3MAZ A;  1LUN A;  1A1B A;  1AB2 A;  2Y1N A;  4JE4 A;  1I3Z A;  4P9Z A;  1LUK A;  5KAZ A;  2AOB A;  1G83 A;  1KSW A;  3S9K A;  4OHE A;  1H9O A;  1O47 A;  3QWX X;  4K11 A;  3TKZ A;  1O4L A;  4GPL B;  3EAZ A;  3N84 A;  2PNB A;  2C0O A;  2MK2 A;  1SHA A;  4FL3 A;  4U1P A;  1UUS A;  2HUW A;  1JWO A;  4A4C A;  2SHP A;  1LCJ A;  2DVJ A;  1F2F A;  5IBM A;  1QCF A;  4LUE A;  2KNO A;  1O4H A;  3OV1 A;  1RJA A;  5DC9 A;  5CDW A;  3CWG A;  5DC0 B;  1JYU A;  2Y1M A;  2GE9 A;  3VS0 A;  2IZV A;  5HKZ A;  5EEQ A;  5IBS A;  2DM0 A;  3HCK A;  2EYY A;  1OO3 A;  1LUM A;  4K45 A;  2DX0 A;  1CJ1 A;  2CIA A;  4FL2 A;  1IJR A;  2C0I A;  2CS0 A;  4F59 A;  1O48 A;  4X6S A;  3KFJ A;  2QMS A;  1BHF A;  1B47 A;  1M27 A;  5GJI A;  3VS6 A;  4A4B A;  2RMX A;  2MRK A;  5J3X A;  3BUW B;  3GXX A;  2L3T A;  1WQU A;  2RVF A;  1Y57 A;  1FHS A;  1O4E A;  1AYC A;  3S8L A;  2L4K A;  1O4K A;  1A08 A;  1JU5 A;  3S8O A;  3WA4 A;  2MRJ A;  1BKL A;  3CBL A;  1O4Q A;  2DLY A;  2VIF A;  4DGP A;  4TZI A;  2CI9 A;  1NZL A;  1LKK A;  2HDX A;  2XP1 A;  1O4C A;  1SHD A;  1X0N A;  1HCS B;  1Z3K A;  4XZ1 A;  2ABL A;  3VS2 A;  1LCK A;  1AYD A;  1D1Z A;  3EAC A;  1CSZ A;  1D4T A;  3M7F A;  2EL8 A;  1SPS A;  1A07 A;  1KA6 A;  1O4G A;  2H46 E;  1BLJ A;  3N7Y A;  2DLZ A;  1D4W A;  2HDV A;  3N8M A;  3OB1 B;  1A81 A;  2K7A B;  2EKX A;  4DGX A;  4EIH A;  4WWQ A;  2YU7 A;  3VS3 A;  1O4J A;  1GRI A;  3T04 A;  1CSY A;  4GL9 E;  3PQZ A;  2MQI A;  2B3O A;  3OB2 B;  1BKM A;  1CWE A;  3GQI B;  1O4F A;  1O4A A;  2IUG A;  3US4 A;  1AOU F;  3PJP A;  1BHH A;  1MW4 A;  3VRZ A;  1YVH A;  3IN8 A;  2PNA A;  3C7I A;  1BM2 A;  3BKB A;  2LQN A;  1BMB A;  1AD5 A;  3PS5 A;  5BO4 A;  1KA7 A;  1R1P A;  1BFJ A;  2Y3A B;  3MXY A;  3PSJ A;  1JYQ A;  2DCR A;  2L6K A;  1BHH B;  5DC4 A;  2AOA A;  4H34 A;  1A1A A;  1O4N A;  2EU0 A;  1QAD A;  1FU6 A;  1LKL A;  2LNW A;  3K2M A;  3VS5 A;  3BUM B;  5DF6 A;  4OHL A;  2ETZ A;  3VRP A;  4LUD A;  3CXL A;  1O42 A;  4FBN A;  1CWD L;  4NWG A;  5AXI A;  1K9A A;  2FO0 A;  1O4D A;  2EYZ A;  5HKW A;  1HCT B;  3NHN A;  2EYV A;  1O45 A;  1O43 A;  2BBU A;  5I6V A;  2CRH A;  2HMH A;  4NWF A;  4OHH A;  4D8K A;  1A09 A;  4E68 A;  1A1C A;  1FBZ A;  1M61 A;  1O41 A;  1FU5 A;  1SHB A;  2H8H A;  1O44 A;  1ZFP E;  2HCK A;  3S8N A;  2LCT A;  3VRO A;  1AYB A;  1RQQ C;  4L1B B;  1TZE E;  1AOT F;  2IUH A;  3BUX B;  5D0J A;  2PLE A;  2LNX A;  1XA6 A;  4EY0 A;  1X6C A;  2SRC A;  2JYQ A;  5EHP A;  1QG1 E;  3PSK A;  3MXC A;  5EG3 B;  2C0T A;  4F5A A;  2MC1 A;  4QSY A;  1SKJ A;  1BLK A;  1RPY A;  1O4R A;  4ROJ A;  1KC2 A;  4JGH A;  2EO3 A;  3ZNI A;  1AYA A;  1LUI A;  2ECD A;  3CD3 A;  1BG1 A;  2OZO A;  3OVE A;  3VS1 A;  3HIZ B;  3UYO A;  1IS0 A;  3TL0 A;  4E93 A;  2PTK A;  3IN7 A;  1A1E A;  2OQ1 A;  1O4I A;  1TCE A;  5GJH A;  3PFV A;  3UF4 A;  2CR4 A;  4H1O A;  1MIL A;  1FBV A;  3VRQ A;  1O4O A;  1R1Q A;  4JEG A;  2K79 B;  2AUG A;  1O46 A;  1X27 A;  2LQW A;  3QWY A;  1O4P A;  1JYR A;  2CBL A;  2CI8 A;  2H5K A;  2C9W A;  4M4Z A;  3OP0 A;  3BUN B;  1O4B A;  1R1S A;  4K44 A;  3BUO B;  4OHD A;  2KK6 A;  1OPL A;  1FMK A;  2IUI A;  4XZ0 A;  5EEL A;  1O4M A;  1F1W A;  2EOB A;  2YSX A;  4P9V A;  1BFI A;  1UUR A;  4OHI A;  3VRR A;  1OO4 A;  2GSB A;  1GHU A;  1Y1U A;  1P13 A;  1SPR A;  2FCI A;  1BF5 A;  5EHR A;  1YVL A;  2EO6 A;  3VS4 A;  1PIC A;  3VRY A;  3VGO A;  2RSY A;  4GWF A;  5HKY A;  3IMJ A;  2ROR A;  1FYR A;  4F5B A;  3GXW A;  2PLD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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