1O4GA

Crystal structure of sh2 in complex with dpi59.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4gA00
2HDXA 4OHIA 1SHBA 1RJAA 1CWDL 5DC0B 1O4GA 3VS3A 1AOUF 2SRCA 1BHHA 2PTKA 1O43A 3C7IA 5HKWA 1A1BA 2EU0A 2DLYA 3QWYA 2C0OA 4JGHA 2HMHA 1R1PA 4DGPA 2MQIA 1O4MA 1D4TA 2H8HA 3S8NA 5AULA 1LCKA 1H9OA 1QADA 1R1SA 3BUXB 3CWGA 2BBUA 2PLEA 1K9AA 2MK2A 1O4BA 2K7AB 3OVEA 1AYBA 1UUSA 1CJ1A 2LCTA 4QSYA 2FO0A 2Y1NA 3PQZA 2YSXA 3BUMB 3GXXA 2C0IA 4TZIA 3OV1A 1BKLA 2ECDA 2LQWA 1SHAA 5EHRA 1X0NA 1O48A 5EELA 4A4BA 2PLDA 3GXWA 2OQ1A 1AD5A 1JWOA 3VS4A 3N8MA 3HIZB 4GPLB 2LQNA 1OO3A 1OPLA 4X6SA 1KC2A 2AUGA 3VRRA 1IS0A 1XA6A 3OB2B 4D8KA 1FMKA 1A81A 1G83A 5DF6A 4K44A 1BHHB 4XZ1A 1I3ZA 2H5KA 3PSKA 3CBLA 2KK6A 4OHDA 1A1AA 2EOBA 1KA7A 1B47A 2CIAA 1O4QA 3S8OA 1TZEE 1AYAA 3VRPA 3CD3A 3K2MA 1A1CA 5GJHA 1CSZA 1X6CA 2IUHA 1CSYA 1M27A 3S9KA 1BF5A 3TKZA 1YVLA 3ZNIA 1PICA 5IBSA 2SHPA 3VS7A 1O46A 1FBZA 2QMSA 1O4CA 1SHDA 1KA6A 1AYCA 2LNXA 2EYZA 1SPRA 2IUIA 1BG1A 1WQUA 1SPSA 3QWXX 2L6KA 5BO4A 4F5BA 4H1OA 1FYRA 4GWFA 1TCEA 5D0JA 3MAZA 1FU6A 2IUGA 3HHMB 1QCFA 2JYQA 1O41A 2MC1A 2HDVA 2ABLA 3WA4A 3IMJA 2KNOA 3M7FA 1JU5A 4NWFA 1GHUA 1LUMA 1SKJA 1O4JA 4ROJA 1FHSA 2CR4A 5HKYA 1O4RA 2OZOA 5J3XA 2CI8A 4OHLA 4JE4A 3N84A 1A07A 1A09A 4U17A 1X27A 1O47A 4XZ0A 5EHPA 4L1BB 1KSWA 4DGXA 1ZFPE 1O4EA 2EYVA 1OO4A 2EO3A 3IMDA 3S8LA 1F1WA 2AOAA 3KFJA 3IN7A 5AXIA 4EY0A 3T04A 4NWGA 3TL0A 1D4WA 1O4LA 1O4FA 1O4OA 3PJPA 2C9WA 2DCRA 2EYYA 2Y1MA 3BUNB 2GSBA 2EL8A 3N7YA 2DM0A 3BUOB 2RORA 3VRNA 4E93A 1AYDA 2IZVA 3VRZA 1Y1UA 4F5AA 1FU5A 4LUEA 2CRHA 4E68A 3BKBA 3PS5A 5I6VA 2DVJA 2XP1A 4H34A 2LNWA 4U1PA 1HCTB 2L3TA 4FL2A 4K2RA 3PSJA 1F2FA 1YVHA 1O4KA 3EAZA 1AB2A 4M4ZA 3UYOA 2L4KA 4K45A 4GL9E 1OPKA 2CI9A 2EKXA 1O45A 1D1ZA 1A1EA 4A4CA 3VROA 5DC4A 1JYRA 3NHNA 2YU7A 4P9ZA 5CDWA 1O4AA 5DC9A 1A08A 1UURA 3CXLA 2RMXA 3VGOA 1R1QA 1AOTF 2RVFA 1BFIA 1O4NA 1FBVA 2B3OA 3BUWB 4JEGA 2C0TA 1Y57A 1O4IA 1LKLA 2K79B 3PFVA 2PNAA 4P9VA 4EIHA 3VS6A 1JYQA 3HCKA 1O4PA 1IJRA 1JYUA 2DX0A 1BM2A 1QG1E 1LCJA 2VIFA 4OHEA 1O44A 1M61A 2FCIA 3GQIB 5KAZA 3PLFB 3VS5A 5EG3B 2CS0A 1MILA 2PNBA 1RQQC 3VRQA 2RSYA 4FBNA 1O4DA 1NRVA 4F59A 2ETZA 4WWQA 1NZVA 1HCSB 3OP0A 1GRIA 1MW4A 3MXYA 1BLKA 2H46E 3OB1B 3VS2A 1LUNA 1BHFA 4OHHA 1LUIA 5HKZA 1BMBA 5IBMA 1P13A 1O49A 3US4A 4FL3A 1O42A 5EEQA 1BKMA 1Z3KA 3UF4A 2MRJA 2HUWA 1RPYA 2AOBA 4K11A 3EACA 3VS0A 2DLZA 1BLJA 1BFJA 1LUKA 1O4HA 4LUDA 3VRYA 2Y3AB 2GE9A 3VS1A 2HCKA 1NZLA 2MRKA 5GJIA 1CWEA 1LKKA 2CBLA 2EO6A 3IN8A 3MXCA
chains in the Genus database with same CATH superfamily
2HDXA 4OHIA 1SHBA 1RJAA 1CWDL 5DC0B 1O4GA 3VS3A 1AOUF 2SRCA 1BHHA 2PTKA 1O43A 3C7IA 5HKWA 1A1BA 2EU0A 2DLYA 3QWYA 2C0OA 4JGHA 2HMHA 1R1PA 4DGPA 2MQIA 1O4MA 1D4TA 2H8HA 3S8NA 5AULA 1LCKA 1H9OA 1QADA 1R1SA 3BUXB 3CWGA 2BBUA 2PLEA 1K9AA 2MK2A 1O4BA 2K7AB 3OVEA 1AYBA 1UUSA 1CJ1A 2LCTA 4QSYA 2FO0A 2Y1NA 3PQZA 2YSXA 3BUMB 3GXXA 3K2TA 2C0IA 4TZIA 3OV1A 1BKLA 2ECDA 2LQWA 1SHAA 5EHRA 1X0NA 1O48A 5EELA 4A4BA 2PLDA 3GXWA 2OQ1A 1AD5A 1JWOA 3VS4A 3N8MA 3HIZB 4GPLB 2LQNA 1OO3A 1OPLA 4X6SA 1KC2A 2AUGA 3VRRA 1IS0A 1XA6A 3OB2B 4D8KA 1FMKA 1A81A 1G83A 5DF6A 4K44A 1BHHB 4XZ1A 1I3ZA 2H5KA 3PSKA 3CBLA 2KK6A 4OHDA 1A1AA 2EOBA 1KA7A 1B47A 2CIAA 1O4QA 3S8OA 1TZEE 1AYAA 3VRPA 3CD3A 3K2MA 1A1CA 5GJHA 1CSZA 1X6CA 2IUHA 1CSYA 1M27A 3S9KA 1BF5A 3TKZA 1YVLA 3ZNIA 1PICA 5IBSA 2SHPA 3VS7A 1O46A 1FBZA 2QMSA 1O4CA 1SHDA 1KA6A 1AYCA 2LNXA 2EYZA 1SPRA 2IUIA 1BG1A 1WQUA 1SPSA 3QWXX 2L6KA 5BO4A 4F5BA 4H1OA 1FYRA 4GWFA 1TCEA 5D0JA 3MAZA 1FU6A 2IUGA 3HHMB 1QCFA 2JYQA 1O41A 2MC1A 2HDVA 2ABLA 3WA4A 3IMJA 2KNOA 3M7FA 1JU5A 4NWFA 1GHUA 1LUMA 1SKJA 1O4JA 4ROJA 1FHSA 2CR4A 5HKYA 1O4RA 2OZOA 5J3XA 2CI8A 4OHLA 4JE4A 3N84A 1A07A 1A09A 4U17A 1X27A 1O47A 4XZ0A 5EHPA 4L1BB 1KSWA 4DGXA 1ZFPE 1O4EA 2EYVA 1OO4A 2EO3A 3IMDA 3S8LA 1F1WA 2AOAA 3KFJA 3IN7A 5AXIA 4EY0A 3T04A 4NWGA 3TL0A 1D4WA 1O4LA 1O4FA 1O4OA 3PJPA 2C9WA 2DCRA 2EYYA 3LYVA 2Y1MA 3BUNB 2GSBA 2EL8A 3N7YA 2DM0A 3BUOB 2RORA 3VRNA 4E93A 1AYDA 2IZVA 3VRZA 1Y1UA 4F5AA 1FU5A 4LUEA 2CRHA 4E68A 3BKBA 3PS5A 5I6VA 2DVJA 2XP1A 4H34A 2LNWA 4U1PA 1HCTB 2L3TA 4FL2A 4K2RA 3PSJA 1F2FA 1YVHA 1O4KA 3EAZA 1AB2A 4M4ZA 3UYOA 2L4KA 4K45A 4GL9E 1OPKA 2CI9A 2EKXA 1O45A 1D1ZA 1A1EA 4A4CA 3VROA 5DC4A 1JYRA 3NHNA 2YU7A 4P9ZA 5CDWA 1O4AA 5DC9A 1A08A 1UURA 3CXLA 2RMXA 3VGOA 1R1QA 1AOTF 2RVFA 1BFIA 1O4NA 1FBVA 2B3OA 3BUWB 4JEGA 2C0TA 1Y57A 1O4IA 1LKLA 2K79B 3PFVA 2PNAA 4P9VA 4EIHA 3VS6A 1JYQA 3HCKA 1O4PA 1IJRA 1JYUA 2DX0A 1BM2A 1QG1E 1LCJA 2VIFA 4OHEA 1O44A 1M61A 2FCIA 3GQIB 5KAZA 3PLFB 3VS5A 5EG3B 2CS0A 1MILA 2PNBA 1RQQC 3VRQA 2RSYA 4FBNA 1O4DA 1NRVA 4F59A 2ETZA 2KGYA 4WWQA 1NZVA 1HCSB 3OP0A 1GRIA 1MW4A 3MXYA 1BLKA 2H46E 3OB1B 3VS2A 1LUNA 1BHFA 4OHHA 1LUIA 5HKZA 1BMBA 5IBMA 1P13A 1O49A 3US4A 4FL3A 1O42A 5EEQA 1BKMA 1Z3KA 3UF4A 2MRJA 2HUWA 1RPYA 2AOBA 4K11A 3EACA 3VS0A 2DLZA 1BLJA 1BFJA 1LUKA 2LRAA 1O4HA 4LUDA 3VRYA 2Y3AB 2GE9A 3VS1A 2HCKA 1NZLA 2MRKA 5GJIA 1CWEA 1LKKA 2CBLA 2EO6A 3IN8A 3MXCA
chains in the Genus database with same CATH topology
2HDXA 4OHIA 1SHBA 1RJAA 1CWDL 5DC0B 1O4GA 3VS3A 1AOUF 2SRCA 1BHHA 2PTKA 1O43A 3C7IA 5HKWA 1A1BA 2EU0A 2DLYA 3QWYA 2C0OA 4JGHA 2HMHA 1R1PA 4DGPA 2MQIA 1O4MA 1D4TA 2H8HA 3S8NA 5AULA 1LCKA 1H9OA 1QADA 1R1SA 3BUXB 3CWGA 2BBUA 2PLEA 1K9AA 2MK2A 1O4BA 2K7AB 3OVEA 1AYBA 1UUSA 1CJ1A 2LCTA 4QSYA 2FO0A 2Y1NA 3PQZA 2YSXA 3BUMB 3GXXA 2C0IA 4TZIA 3OV1A 1BKLA 2ECDA 2LQWA 1SHAA 5EHRA 1X0NA 1O48A 5EELA 4A4BA 2PLDA 3GXWA 2OQ1A 1AD5A 1JWOA 3VS4A 3N8MA 3HIZB 4GPLB 2LQNA 1OO3A 1OPLA 4X6SA 1KC2A 2AUGA 3VRRA 1IS0A 1XA6A 3OB2B 4D8KA 1FMKA 1A81A 1G83A 5DF6A 4K44A 1BHHB 4XZ1A 1I3ZA 2H5KA 3PSKA 3CBLA 2KK6A 4OHDA 1A1AA 2EOBA 1KA7A 1B47A 2CIAA 1O4QA 3S8OA 1TZEE 1AYAA 3VRPA 3CD3A 3K2MA 1A1CA 5GJHA 1CSZA 1X6CA 2IUHA 1CSYA 1M27A 3S9KA 1BF5A 3TKZA 1YVLA 3ZNIA 1PICA 5IBSA 2SHPA 3VS7A 1O46A 1FBZA 2QMSA 1O4CA 1SHDA 1KA6A 1AYCA 2LNXA 2EYZA 1SPRA 2IUIA 1BG1A 1WQUA 1SPSA 3QWXX 2L6KA 5BO4A 4F5BA 4H1OA 1FYRA 4GWFA 1TCEA 5D0JA 3MAZA 1FU6A 2IUGA 3HHMB 1QCFA 2JYQA 1O41A 2MC1A 2HDVA 2ABLA 3WA4A 3IMJA 2KNOA 3M7FA 1JU5A 4NWFA 1GHUA 1LUMA 1SKJA 1O4JA 4ROJA 1FHSA 2CR4A 5HKYA 1O4RA 2OZOA 5J3XA 2CI8A 4OHLA 4JE4A 3N84A 1A07A 1A09A 4U17A 1X27A 1O47A 4XZ0A 5EHPA 4L1BB 1KSWA 4DGXA 1ZFPE 1O4EA 2EYVA 1OO4A 2EO3A 3IMDA 3S8LA 1F1WA 2AOAA 3KFJA 3IN7A 5AXIA 4EY0A 3T04A 4NWGA 3TL0A 1D4WA 1O4LA 1O4FA 1O4OA 3PJPA 2C9WA 2DCRA 2EYYA 2Y1MA 3BUNB 2GSBA 2EL8A 3N7YA 2DM0A 3BUOB 2RORA 3VRNA 4E93A 1AYDA 2IZVA 3VRZA 1Y1UA 4F5AA 1FU5A 4LUEA 2CRHA 4E68A 3BKBA 3PS5A 5I6VA 2DVJA 2XP1A 4H34A 2LNWA 4U1PA 1HCTB 2L3TA 4FL2A 4K2RA 3PSJA 1F2FA 1YVHA 1O4KA 3EAZA 1AB2A 4M4ZA 3UYOA 2L4KA 4K45A 4GL9E 1OPKA 2CI9A 2EKXA 1O45A 1D1ZA 1A1EA 4A4CA 3VROA 5DC4A 1JYRA 3NHNA 2YU7A 4P9ZA 5CDWA 1O4AA 5DC9A 1A08A 1UURA 3CXLA 2RMXA 3VGOA 1R1QA 1AOTF 2RVFA 1BFIA 1O4NA 1FBVA 2B3OA 3BUWB 4JEGA 2C0TA 1Y57A 1O4IA 1LKLA 2K79B 3PFVA 2PNAA 4P9VA 4EIHA 3VS6A 1JYQA 3HCKA 1O4PA 1IJRA 1JYUA 2DX0A 1BM2A 1QG1E 1LCJA 2VIFA 4OHEA 1O44A 1M61A 2FCIA 3GQIB 5KAZA 3PLFB 3VS5A 5EG3B 2CS0A 1MILA 2PNBA 1RQQC 3VRQA 2RSYA 4FBNA 1O4DA 1NRVA 4F59A 2ETZA 4WWQA 1NZVA 1HCSB 3OP0A 1GRIA 1MW4A 3MXYA 1BLKA 2H46E 3OB1B 3VS2A 1LUNA 1BHFA 4OHHA 1LUIA 5HKZA 1BMBA 5IBMA 1P13A 1O49A 3US4A 4FL3A 1O42A 5EEQA 1BKMA 1Z3KA 3UF4A 2MRJA 2HUWA 1RPYA 2AOBA 4K11A 3EACA 3VS0A 2DLZA 1BLJA 1BFJA 1LUKA 1O4HA 4LUDA 3VRYA 2Y3AB 2GE9A 3VS1A 2HCKA 1NZLA 2MRKA 5GJIA 1CWEA 1LKKA 2CBLA 2EO6A 3IN8A 3MXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HDX A;  4OHI A;  1SHB A;  1RJA A;  1CWD L;  5DC0 B;  1O4G A;  3VS3 A;  1AOU F;  2SRC A;  1BHH A;  2PTK A;  1O43 A;  3C7I A;  5HKW A;  1A1B A;  2EU0 A;  2DLY A;  3QWY A;  2C0O A;  4JGH A;  2HMH A;  1R1P A;  4DGP A;  2MQI A;  1O4M A;  1D4T A;  2H8H A;  3S8N A;  5AUL A;  1LCK A;  1H9O A;  1QAD A;  1R1S A;  3BUX B;  3CWG A;  2BBU A;  2PLE A;  1K9A A;  2MK2 A;  1O4B A;  2K7A B;  3OVE A;  1AYB A;  1UUS A;  1CJ1 A;  2LCT A;  4QSY A;  2FO0 A;  2Y1N A;  3PQZ A;  2YSX A;  3BUM B;  3GXX A;  2C0I A;  4TZI A;  3OV1 A;  1BKL A;  2ECD A;  2LQW A;  1SHA A;  5EHR A;  1X0N A;  1O48 A;  5EEL A;  4A4B A;  2PLD A;  3GXW A;  2OQ1 A;  1AD5 A;  1JWO A;  3VS4 A;  3N8M A;  3HIZ B;  4GPL B;  2LQN A;  1OO3 A;  1OPL A;  4X6S A;  1KC2 A;  2AUG A;  3VRR A;  1IS0 A;  1XA6 A;  3OB2 B;  4D8K A;  1FMK A;  1A81 A;  1G83 A;  5DF6 A;  4K44 A;  1BHH B;  4XZ1 A;  1I3Z A;  2H5K A;  3PSK A;  3CBL A;  2KK6 A;  4OHD A;  1A1A A;  2EOB A;  1KA7 A;  1B47 A;  2CIA A;  1O4Q A;  3S8O A;  1TZE E;  1AYA A;  3VRP A;  3CD3 A;  3K2M A;  1A1C A;  5GJH A;  1CSZ A;  1X6C A;  2IUH A;  1CSY A;  1M27 A;  3S9K A;  1BF5 A;  3TKZ A;  1YVL A;  3ZNI A;  1PIC A;  5IBS A;  2SHP A;  3VS7 A;  1O46 A;  1FBZ A;  2QMS A;  1O4C A;  1SHD A;  1KA6 A;  1AYC A;  2LNX A;  2EYZ A;  1SPR A;  2IUI A;  1BG1 A;  1WQU A;  1SPS A;  3QWX X;  2L6K A;  5BO4 A;  4F5B A;  4H1O A;  1FYR A;  4GWF A;  1TCE A;  5D0J A;  3MAZ A;  1FU6 A;  2IUG A;  3HHM B;  1QCF A;  2JYQ A;  1O41 A;  2MC1 A;  2HDV A;  2ABL A;  3WA4 A;  3IMJ A;  2KNO A;  3M7F A;  1JU5 A;  4NWF A;  1GHU A;  1LUM A;  1SKJ A;  1O4J A;  4ROJ A;  1FHS A;  2CR4 A;  5HKY A;  1O4R A;  2OZO A;  5J3X A;  2CI8 A;  4OHL A;  4JE4 A;  3N84 A;  1A07 A;  1A09 A;  4U17 A;  1X27 A;  1O47 A;  4XZ0 A;  5EHP A;  4L1B B;  1KSW A;  4DGX A;  1ZFP E;  1O4E A;  2EYV A;  1OO4 A;  2EO3 A;  3IMD A;  3S8L A;  1F1W A;  2AOA A;  3KFJ A;  3IN7 A;  5AXI A;  4EY0 A;  3T04 A;  4NWG A;  3TL0 A;  1D4W A;  1O4L A;  1O4F A;  1O4O A;  3PJP A;  2C9W A;  2DCR A;  2EYY A;  2Y1M A;  3BUN B;  2GSB A;  2EL8 A;  3N7Y A;  2DM0 A;  3BUO B;  2ROR A;  3VRN A;  4E93 A;  1AYD A;  2IZV A;  3VRZ A;  1Y1U A;  4F5A A;  1FU5 A;  4LUE A;  2CRH A;  4E68 A;  3BKB A;  3PS5 A;  5I6V A;  2DVJ A;  2XP1 A;  4H34 A;  2LNW A;  4U1P A;  1HCT B;  2L3T A;  4FL2 A;  4K2R A;  3PSJ A;  1F2F A;  1YVH A;  1O4K A;  3EAZ A;  1AB2 A;  4M4Z A;  3UYO A;  2L4K A;  4K45 A;  4GL9 E;  1OPK A;  2CI9 A;  2EKX A;  1O45 A;  1D1Z A;  1A1E A;  4A4C A;  3VRO A;  5DC4 A;  1JYR A;  3NHN A;  2YU7 A;  4P9Z A;  5CDW A;  1O4A A;  5DC9 A;  1A08 A;  1UUR A;  3CXL A;  2RMX A;  3VGO A;  1R1Q A;  1AOT F;  2RVF A;  1BFI A;  1O4N A;  1FBV A;  2B3O A;  3BUW B;  4JEG A;  2C0T A;  1Y57 A;  1O4I A;  1LKL A;  2K79 B;  3PFV A;  2PNA A;  4P9V A;  4EIH A;  3VS6 A;  1JYQ A;  3HCK A;  1O4P A;  1IJR A;  1JYU A;  2DX0 A;  1BM2 A;  1QG1 E;  1LCJ A;  2VIF A;  4OHE A;  1O44 A;  1M61 A;  2FCI A;  3GQI B;  5KAZ A;  3PLF B;  3VS5 A;  5EG3 B;  2CS0 A;  1MIL A;  2PNB A;  1RQQ C;  3VRQ A;  2RSY A;  4FBN A;  1O4D A;  1NRV A;  4F59 A;  2ETZ A;  4WWQ A;  1NZV A;  1HCS B;  3OP0 A;  1GRI A;  1MW4 A;  3MXY A;  1BLK A;  2H46 E;  3OB1 B;  3VS2 A;  1LUN A;  1BHF A;  4OHH A;  1LUI A;  5HKZ A;  1BMB A;  5IBM A;  1P13 A;  1O49 A;  3US4 A;  4FL3 A;  1O42 A;  5EEQ A;  1BKM A;  1Z3K A;  3UF4 A;  2MRJ A;  2HUW A;  1RPY A;  2AOB A;  4K11 A;  3EAC A;  3VS0 A;  2DLZ A;  1BLJ A;  1BFJ A;  1LUK A;  1O4H A;  4LUD A;  3VRY A;  2Y3A B;  2GE9 A;  3VS1 A;  2HCK A;  1NZL A;  2MRK A;  5GJI A;  1CWE A;  1LKK A;  2CBL A;  2EO6 A;  3IN8 A;  3MXC A; 
#chains in the Genus database with same CATH topology
 2HDX A;  4OHI A;  1SHB A;  1RJA A;  1CWD L;  5DC0 B;  1O4G A;  3VS3 A;  1AOU F;  2SRC A;  1BHH A;  2PTK A;  1O43 A;  3C7I A;  5HKW A;  1A1B A;  2EU0 A;  2DLY A;  3QWY A;  2C0O A;  4JGH A;  2HMH A;  1R1P A;  4DGP A;  2MQI A;  1O4M A;  1D4T A;  2H8H A;  3S8N A;  5AUL A;  1LCK A;  1H9O A;  1QAD A;  1R1S A;  3BUX B;  3CWG A;  2BBU A;  2PLE A;  1K9A A;  2MK2 A;  1O4B A;  2K7A B;  3OVE A;  1AYB A;  1UUS A;  1CJ1 A;  2LCT A;  4QSY A;  2FO0 A;  2Y1N A;  3PQZ A;  2YSX A;  3BUM B;  3GXX A;  3K2T A;  2C0I A;  4TZI A;  3OV1 A;  1BKL A;  2ECD A;  2LQW A;  1SHA A;  5EHR A;  1X0N A;  1O48 A;  5EEL A;  4A4B A;  2PLD A;  3GXW A;  2OQ1 A;  1AD5 A;  1JWO A;  3VS4 A;  3N8M A;  3HIZ B;  4GPL B;  2LQN A;  1OO3 A;  1OPL A;  4X6S A;  1KC2 A;  2AUG A;  3VRR A;  1IS0 A;  1XA6 A;  3OB2 B;  4D8K A;  1FMK A;  1A81 A;  1G83 A;  5DF6 A;  4K44 A;  1BHH B;  4XZ1 A;  1I3Z A;  2H5K A;  3PSK A;  3CBL A;  2KK6 A;  4OHD A;  1A1A A;  2EOB A;  1KA7 A;  1B47 A;  2CIA A;  1O4Q A;  3S8O A;  1TZE E;  1AYA A;  3VRP A;  3CD3 A;  3K2M A;  1A1C A;  5GJH A;  1CSZ A;  1X6C A;  2IUH A;  1CSY A;  1M27 A;  3S9K A;  1BF5 A;  3TKZ A;  1YVL A;  3ZNI A;  1PIC A;  5IBS A;  2SHP A;  3VS7 A;  1O46 A;  1FBZ A;  2QMS A;  1O4C A;  1SHD A;  1KA6 A;  1AYC A;  2LNX A;  2EYZ A;  1SPR A;  2IUI A;  1BG1 A;  1WQU A;  1SPS A;  3QWX X;  2L6K A;  5BO4 A;  4F5B A;  4H1O A;  1FYR A;  4GWF A;  1TCE A;  5D0J A;  3MAZ A;  1FU6 A;  2IUG A;  3HHM B;  1QCF A;  2JYQ A;  1O41 A;  2MC1 A;  2HDV A;  2ABL A;  3WA4 A;  3IMJ A;  2KNO A;  3M7F A;  1JU5 A;  4NWF A;  1GHU A;  1LUM A;  1SKJ A;  1O4J A;  4ROJ A;  1FHS A;  2CR4 A;  5HKY A;  1O4R A;  2OZO A;  5J3X A;  2CI8 A;  4OHL A;  4JE4 A;  3N84 A;  1A07 A;  1A09 A;  4U17 A;  1X27 A;  1O47 A;  4XZ0 A;  5EHP A;  4L1B B;  1KSW A;  4DGX A;  1ZFP E;  1O4E A;  2EYV A;  1OO4 A;  2EO3 A;  3IMD A;  3S8L A;  1F1W A;  2AOA A;  3KFJ A;  3IN7 A;  5AXI A;  4EY0 A;  3T04 A;  4NWG A;  3TL0 A;  1D4W A;  1O4L A;  1O4F A;  1O4O A;  3PJP A;  2C9W A;  2DCR A;  2EYY A;  3LYV A;  2Y1M A;  3BUN B;  2GSB A;  2EL8 A;  3N7Y A;  2DM0 A;  3BUO B;  2ROR A;  3VRN A;  4E93 A;  1AYD A;  2IZV A;  3VRZ A;  1Y1U A;  4F5A A;  1FU5 A;  4LUE A;  2CRH A;  4E68 A;  3BKB A;  3PS5 A;  5I6V A;  2DVJ A;  2XP1 A;  4H34 A;  2LNW A;  4U1P A;  1HCT B;  2L3T A;  4FL2 A;  4K2R A;  3PSJ A;  1F2F A;  1YVH A;  1O4K A;  3EAZ A;  1AB2 A;  4M4Z A;  3UYO A;  2L4K A;  4K45 A;  4GL9 E;  1OPK A;  2CI9 A;  2EKX A;  1O45 A;  1D1Z A;  1A1E A;  4A4C A;  3VRO A;  5DC4 A;  1JYR A;  3NHN A;  2YU7 A;  4P9Z A;  5CDW A;  1O4A A;  5DC9 A;  1A08 A;  1UUR A;  3CXL A;  2RMX A;  3VGO A;  1R1Q A;  1AOT F;  2RVF A;  1BFI A;  1O4N A;  1FBV A;  2B3O A;  3BUW B;  4JEG A;  2C0T A;  1Y57 A;  1O4I A;  1LKL A;  2K79 B;  3PFV A;  2PNA A;  4P9V A;  4EIH A;  3VS6 A;  1JYQ A;  3HCK A;  1O4P A;  1IJR A;  1JYU A;  2DX0 A;  1BM2 A;  1QG1 E;  1LCJ A;  2VIF A;  4OHE A;  1O44 A;  1M61 A;  2FCI A;  3GQI B;  5KAZ A;  3PLF B;  3VS5 A;  5EG3 B;  2CS0 A;  1MIL A;  2PNB A;  1RQQ C;  3VRQ A;  2RSY A;  4FBN A;  1O4D A;  1NRV A;  4F59 A;  2ETZ A;  2KGY A;  4WWQ A;  1NZV A;  1HCS B;  3OP0 A;  1GRI A;  1MW4 A;  3MXY A;  1BLK A;  2H46 E;  3OB1 B;  3VS2 A;  1LUN A;  1BHF A;  4OHH A;  1LUI A;  5HKZ A;  1BMB A;  5IBM A;  1P13 A;  1O49 A;  3US4 A;  4FL3 A;  1O42 A;  5EEQ A;  1BKM A;  1Z3K A;  3UF4 A;  2MRJ A;  2HUW A;  1RPY A;  2AOB A;  4K11 A;  3EAC A;  3VS0 A;  2DLZ A;  1BLJ A;  1BFJ A;  1LUK A;  2LRA A;  1O4H A;  4LUD A;  3VRY A;  2Y3A B;  2GE9 A;  3VS1 A;  2HCK A;  1NZL A;  2MRK A;  5GJI A;  1CWE A;  1LKK A;  2CBL A;  2EO6 A;  3IN8 A;  3MXC A; 
#chains in the Genus database with same CATH homology
 2HDX A;  4OHI A;  1SHB A;  1RJA A;  1CWD L;  5DC0 B;  1O4G A;  3VS3 A;  1AOU F;  2SRC A;  1BHH A;  2PTK A;  1O43 A;  3C7I A;  5HKW A;  1A1B A;  2EU0 A;  2DLY A;  3QWY A;  2C0O A;  4JGH A;  2HMH A;  1R1P A;  4DGP A;  2MQI A;  1O4M A;  1D4T A;  2H8H A;  3S8N A;  5AUL A;  1LCK A;  1H9O A;  1QAD A;  1R1S A;  3BUX B;  3CWG A;  2BBU A;  2PLE A;  1K9A A;  2MK2 A;  1O4B A;  2K7A B;  3OVE A;  1AYB A;  1UUS A;  1CJ1 A;  2LCT A;  4QSY A;  2FO0 A;  2Y1N A;  3PQZ A;  2YSX A;  3BUM B;  3GXX A;  2C0I A;  4TZI A;  3OV1 A;  1BKL A;  2ECD A;  2LQW A;  1SHA A;  5EHR A;  1X0N A;  1O48 A;  5EEL A;  4A4B A;  2PLD A;  3GXW A;  2OQ1 A;  1AD5 A;  1JWO A;  3VS4 A;  3N8M A;  3HIZ B;  4GPL B;  2LQN A;  1OO3 A;  1OPL A;  4X6S A;  1KC2 A;  2AUG A;  3VRR A;  1IS0 A;  1XA6 A;  3OB2 B;  4D8K A;  1FMK A;  1A81 A;  1G83 A;  5DF6 A;  4K44 A;  1BHH B;  4XZ1 A;  1I3Z A;  2H5K A;  3PSK A;  3CBL A;  2KK6 A;  4OHD A;  1A1A A;  2EOB A;  1KA7 A;  1B47 A;  2CIA A;  1O4Q A;  3S8O A;  1TZE E;  1AYA A;  3VRP A;  3CD3 A;  3K2M A;  1A1C A;  5GJH A;  1CSZ A;  1X6C A;  2IUH A;  1CSY A;  1M27 A;  3S9K A;  1BF5 A;  3TKZ A;  1YVL A;  3ZNI A;  1PIC A;  5IBS A;  2SHP A;  3VS7 A;  1O46 A;  1FBZ A;  2QMS A;  1O4C A;  1SHD A;  1KA6 A;  1AYC A;  2LNX A;  2EYZ A;  1SPR A;  2IUI A;  1BG1 A;  1WQU A;  1SPS A;  3QWX X;  2L6K A;  5BO4 A;  4F5B A;  4H1O A;  1FYR A;  4GWF A;  1TCE A;  5D0J A;  3MAZ A;  1FU6 A;  2IUG A;  3HHM B;  1QCF A;  2JYQ A;  1O41 A;  2MC1 A;  2HDV A;  2ABL A;  3WA4 A;  3IMJ A;  2KNO A;  3M7F A;  1JU5 A;  4NWF A;  1GHU A;  1LUM A;  1SKJ A;  1O4J A;  4ROJ A;  1FHS A;  2CR4 A;  5HKY A;  1O4R A;  2OZO A;  5J3X A;  2CI8 A;  4OHL A;  4JE4 A;  3N84 A;  1A07 A;  1A09 A;  4U17 A;  1X27 A;  1O47 A;  4XZ0 A;  5EHP A;  4L1B B;  1KSW A;  4DGX A;  1ZFP E;  1O4E A;  2EYV A;  1OO4 A;  2EO3 A;  3IMD A;  3S8L A;  1F1W A;  2AOA A;  3KFJ A;  3IN7 A;  5AXI A;  4EY0 A;  3T04 A;  4NWG A;  3TL0 A;  1D4W A;  1O4L A;  1O4F A;  1O4O A;  3PJP A;  2C9W A;  2DCR A;  2EYY A;  2Y1M A;  3BUN B;  2GSB A;  2EL8 A;  3N7Y A;  2DM0 A;  3BUO B;  2ROR A;  3VRN A;  4E93 A;  1AYD A;  2IZV A;  3VRZ A;  1Y1U A;  4F5A A;  1FU5 A;  4LUE A;  2CRH A;  4E68 A;  3BKB A;  3PS5 A;  5I6V A;  2DVJ A;  2XP1 A;  4H34 A;  2LNW A;  4U1P A;  1HCT B;  2L3T A;  4FL2 A;  4K2R A;  3PSJ A;  1F2F A;  1YVH A;  1O4K A;  3EAZ A;  1AB2 A;  4M4Z A;  3UYO A;  2L4K A;  4K45 A;  4GL9 E;  1OPK A;  2CI9 A;  2EKX A;  1O45 A;  1D1Z A;  1A1E A;  4A4C A;  3VRO A;  5DC4 A;  1JYR A;  3NHN A;  2YU7 A;  4P9Z A;  5CDW A;  1O4A A;  5DC9 A;  1A08 A;  1UUR A;  3CXL A;  2RMX A;  3VGO A;  1R1Q A;  1AOT F;  2RVF A;  1BFI A;  1O4N A;  1FBV A;  2B3O A;  3BUW B;  4JEG A;  2C0T A;  1Y57 A;  1O4I A;  1LKL A;  2K79 B;  3PFV A;  2PNA A;  4P9V A;  4EIH A;  3VS6 A;  1JYQ A;  3HCK A;  1O4P A;  1IJR A;  1JYU A;  2DX0 A;  1BM2 A;  1QG1 E;  1LCJ A;  2VIF A;  4OHE A;  1O44 A;  1M61 A;  2FCI A;  3GQI B;  5KAZ A;  3PLF B;  3VS5 A;  5EG3 B;  2CS0 A;  1MIL A;  2PNB A;  1RQQ C;  3VRQ A;  2RSY A;  4FBN A;  1O4D A;  1NRV A;  4F59 A;  2ETZ A;  4WWQ A;  1NZV A;  1HCS B;  3OP0 A;  1GRI A;  1MW4 A;  3MXY A;  1BLK A;  2H46 E;  3OB1 B;  3VS2 A;  1LUN A;  1BHF A;  4OHH A;  1LUI A;  5HKZ A;  1BMB A;  5IBM A;  1P13 A;  1O49 A;  3US4 A;  4FL3 A;  1O42 A;  5EEQ A;  1BKM A;  1Z3K A;  3UF4 A;  2MRJ A;  2HUW A;  1RPY A;  2AOB A;  4K11 A;  3EAC A;  3VS0 A;  2DLZ A;  1BLJ A;  1BFJ A;  1LUK A;  1O4H A;  4LUD A;  3VRY A;  2Y3A B;  2GE9 A;  3VS1 A;  2HCK A;  1NZL A;  2MRK A;  5GJI A;  1CWE A;  1LKK A;  2CBL A;  2EO6 A;  3IN8 A;  3MXC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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