1O4JA

Crystal structure of sh2 in complex with iso24.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4jA00
4GL9E 1JYQA 1B47A 1O4RA 2EYYA 1O4JA 3IMDA 1BFIA 3T04A 4E68A 1K9AA 3N84A 3S8OA 2DVJA 3PJPA 3IN7A 2EO3A 2LCTA 5DC4A 5I6VA 1X0NA 3CD3A 1AYAA 2IUIA 1KA7A 3QWYA 1AYCA 1O4QA 1A1CA 1UURA 2CBLA 1D4WA 2B3OA 5J3XA 1LCKA 2AOBA 3GQIB 1OPLA 3OB1B 1NZLA 2EL8A 4K2RA 1BFJA 4H34A 5DC9A 1JU5A 4LUEA 1O4MA 1AD5A 1PICA 1O47A 1O4OA 1GRIA 1O4IA 1RPYA 3PQZA 5EG3B 3IN8A 1FYRA 4K45A 3VS5A 5EEQA 1LKLA 1R1QA 1O45A 1QADA 2ECDA 3EACA 3HIZB 2FO0A 1LUMA 4LUDA 2Y1MA 1AYDA 4FL2A 1BM2A 1FHSA 2L6KA 2CI9A 4QSYA 3S8LA 5AULA 3UF4A 1H9OA 3HCKA 2HUWA 1OO4A 4TZIA 3CXLA 3PSKA 1IS0A 5IBSA 1LUKA 4OHLA 1O46A 5KAZA 1AOUF 2RSYA 1F1WA 3MAZA 2XP1A 4DGPA 1A08A 1O49A 2FCIA 3OB2B 2KK6A 1X27A 5DF6A 3NHNA 2ETZA 1D4TA 1OPKA 3BUWB 5BO4A 1G83A 3VS0A 1SHAA 2JYQA 1O4AA 1O4LA 3GXWA 1MILA 5EHRA 1O44A 2QMSA 1D1ZA 1O4NA 2MQIA 2HDXA 4U17A 1X6CA 1R1PA 2H46E 2LQWA 2GE9A 4XZ1A 2BBUA 2PTKA 3S9KA 1BLJA 2C0IA 2K7AB 2VIFA 2C9WA 1O43A 1UUSA 2LQNA 1O41A 2Y1NA 3MXCA 2OZOA 3US4A 1A1AA 3CWGA 2DM0A 4OHDA 3HHMB 1YVHA 1KSWA 1MW4A 5HKWA 3GXXA 4JE4A 1A1EA 3VGOA 3VS7A 1O48A 4ROJA 2H5KA 3VRYA 1Z3KA 1O4KA 3BUOB 1AB2A 1OO3A 1F2FA 4U1PA 2MC1A 2C0OA 4K44A 1AYBA 2PLDA 2RORA 4L1BB 3VRZA 2LNWA 1O4CA 3PS5A 1A07A 1O4BA 2YU7A 3C7IA 5EELA 1HCSB 4OHIA 1BMBA 1QG1E 2SRCA 1WQUA 4JEGA 4K11A 1CWDL 2CS0A 4P9VA 2Y3AB 1BHHB 1BLKA 2IZVA 2LNXA 4M4ZA 2DLZA 4EIHA 2AOAA 1KA6A 3BUMB 1SPSA 1A09A 2MK2A 3UYOA 2IUGA 5IBMA 4OHHA 4F5AA 2KNOA 4NWGA 1LUNA 4X6SA 2PLEA 5CDWA 2CI8A 4OHEA 2ABLA 3K2MA 1FBVA 1FU6A 3TKZA 3OV1A 4H1OA 2YSXA 1SPRA 2GSBA 2RMXA 2HDVA 1CWEA 1O4EA 5AXIA 2L4KA 4GWFA 1TZEE 1M27A 3VRQA 2SHPA 1NRVA 3TL0A 4GPLB 3MXYA 2EOBA 2OQ1A 3PSJA 2CR4A 3VS1A 1BHFA 2MRKA 1ZFPE 1JWOA 2AUGA 2DLYA 2K79B 1BKMA 1P13A 1Y57A 1XA6A 1QCFA 1CSYA 3WA4A 4A4BA 1AOTF 1KC2A 1BF5A 1LUIA 3VROA 3VRPA 1O42A 2L3TA 2CRHA 3VS4A 1SKJA 2PNAA 1A81A 3M7FA 3IMJA 1FMKA 3PFVA 2EYVA 1RQQC 1SHBA 2EO6A 4D8KA 3VRRA 5DC0B 2HMHA 2RVFA 1JYRA 4XZ0A 4A4CA 1M61A 5D0JA 2EKXA 1FU5A 1JYUA 1LKKA 3N7YA 1YVLA 1O4HA 3KFJA 1LCJA 2H8HA 4FL3A 1O4PA 3BKBA 2CIAA 5HKYA 4P9ZA 2PNBA 3N8MA 5EHPA 4NWFA 1Y1UA 5GJIA 1TCEA 1RJAA 1O4GA 1CJ1A 4JGHA 4WWQA 2EYZA 3OVEA 1A1BA 5GJHA 1BKLA 1I3ZA 2MRJA 2C0TA 3QWXX 1O4DA 1CSZA 3BUNB 2EU0A 1GHUA 1BHHA 4E93A 3EAZA 1O4FA 3VS2A 1NZVA 3VS6A 4EY0A 2DCRA 3PLFB 3VS3A 1SHDA 2DX0A 3BUXB 4FBNA 3S8NA 1IJRA 3CBLA 3OP0A 4F59A 1HCTB 5HKZA 4F5BA 4DGXA 1BG1A 2HCKA 1FBZA 3ZNIA 2IUHA 3VRNA 1R1SA
chains in the Genus database with same CATH superfamily
4GL9E 1JYQA 1B47A 1O4RA 2EYYA 1O4JA 3IMDA 1BFIA 3T04A 4E68A 1K9AA 3N84A 3S8OA 2DVJA 3PJPA 3IN7A 2EO3A 2LCTA 5DC4A 5I6VA 1X0NA 3CD3A 1AYAA 2IUIA 1KA7A 3QWYA 1AYCA 1O4QA 1A1CA 1UURA 2CBLA 1D4WA 2B3OA 5J3XA 1LCKA 2AOBA 3GQIB 1OPLA 3OB1B 1NZLA 2EL8A 4K2RA 1BFJA 4H34A 5DC9A 1JU5A 4LUEA 1O4MA 1AD5A 1PICA 1O47A 1O4OA 1GRIA 1O4IA 1RPYA 3PQZA 5EG3B 3IN8A 1FYRA 4K45A 3VS5A 5EEQA 1LKLA 1R1QA 1O45A 1QADA 2ECDA 3EACA 3HIZB 2FO0A 1LUMA 4LUDA 2Y1MA 1AYDA 4FL2A 1BM2A 1FHSA 2L6KA 2CI9A 4QSYA 3S8LA 5AULA 3UF4A 1H9OA 3HCKA 2HUWA 1OO4A 4TZIA 3CXLA 3PSKA 1IS0A 5IBSA 1LUKA 4OHLA 1O46A 5KAZA 1AOUF 2RSYA 1F1WA 3MAZA 2XP1A 4DGPA 1A08A 1O49A 2FCIA 3OB2B 2KGYA 2KK6A 1X27A 5DF6A 3NHNA 2ETZA 1D4TA 1OPKA 3BUWB 5BO4A 1G83A 3VS0A 1SHAA 2JYQA 1O4AA 1O4LA 3GXWA 1MILA 5EHRA 1O44A 2QMSA 1D1ZA 1O4NA 2MQIA 2HDXA 4U17A 1X6CA 1R1PA 2H46E 2LQWA 2GE9A 4XZ1A 2BBUA 2PTKA 3S9KA 1BLJA 2C0IA 2K7AB 2VIFA 2C9WA 1O43A 1UUSA 2LQNA 1O41A 2Y1NA 3MXCA 2OZOA 3US4A 1A1AA 3CWGA 2DM0A 4OHDA 3HHMB 1YVHA 1KSWA 1MW4A 5HKWA 3GXXA 4JE4A 1A1EA 3VGOA 3VS7A 1O48A 4ROJA 2H5KA 3VRYA 1Z3KA 1O4KA 3BUOB 1AB2A 1OO3A 1F2FA 3K2TA 4U1PA 2MC1A 2C0OA 4K44A 1AYBA 2PLDA 2RORA 4L1BB 3VRZA 2LNWA 1O4CA 3PS5A 1A07A 1O4BA 2YU7A 3C7IA 5EELA 1HCSB 4OHIA 1BMBA 1QG1E 2SRCA 1WQUA 4JEGA 4K11A 1CWDL 2CS0A 4P9VA 2Y3AB 1BHHB 1BLKA 2IZVA 2LNXA 4M4ZA 2DLZA 4EIHA 2AOAA 1KA6A 3BUMB 1SPSA 1A09A 2MK2A 3UYOA 2IUGA 5IBMA 4OHHA 4F5AA 2KNOA 4NWGA 1LUNA 4X6SA 2PLEA 5CDWA 2CI8A 4OHEA 2ABLA 3K2MA 1FBVA 1FU6A 3TKZA 3OV1A 4H1OA 2YSXA 1SPRA 2GSBA 2RMXA 2HDVA 1CWEA 1O4EA 5AXIA 2L4KA 4GWFA 1TZEE 1M27A 3VRQA 2SHPA 1NRVA 3TL0A 4GPLB 3MXYA 2EOBA 2OQ1A 3PSJA 2CR4A 3VS1A 1BHFA 2MRKA 1ZFPE 1JWOA 2AUGA 2DLYA 2K79B 1BKMA 1P13A 1Y57A 1XA6A 1QCFA 1CSYA 3WA4A 4A4BA 1AOTF 1KC2A 1BF5A 1LUIA 3VROA 3VRPA 1O42A 2L3TA 2CRHA 3VS4A 1SKJA 2PNAA 1A81A 3M7FA 3IMJA 1FMKA 3PFVA 2EYVA 1RQQC 1SHBA 2EO6A 4D8KA 3VRRA 5DC0B 2HMHA 2RVFA 1JYRA 4XZ0A 4A4CA 1M61A 5D0JA 2EKXA 3LYVA 1FU5A 1JYUA 1LKKA 3N7YA 1YVLA 1O4HA 3KFJA 1LCJA 2H8HA 4FL3A 1O4PA 3BKBA 2CIAA 5HKYA 4P9ZA 2PNBA 3N8MA 5EHPA 4NWFA 1Y1UA 5GJIA 1TCEA 1RJAA 1O4GA 1CJ1A 4JGHA 4WWQA 2EYZA 3OVEA 1A1BA 5GJHA 1BKLA 1I3ZA 2MRJA 2C0TA 3QWXX 1O4DA 1CSZA 3BUNB 2EU0A 1GHUA 1BHHA 4E93A 3EAZA 1O4FA 3VS2A 1NZVA 3VS6A 4EY0A 2DCRA 3PLFB 3VS3A 1SHDA 2DX0A 2LRAA 3BUXB 4FBNA 3S8NA 1IJRA 3CBLA 3OP0A 4F59A 1HCTB 5HKZA 4F5BA 4DGXA 1BG1A 2HCKA 1FBZA 3ZNIA 2IUHA 3VRNA 1R1SA
chains in the Genus database with same CATH topology
4GL9E 1JYQA 1B47A 1O4RA 2EYYA 1O4JA 3IMDA 1BFIA 3T04A 4E68A 1K9AA 3N84A 3S8OA 2DVJA 3PJPA 3IN7A 2EO3A 2LCTA 5DC4A 5I6VA 1X0NA 3CD3A 1AYAA 2IUIA 1KA7A 3QWYA 1AYCA 1O4QA 1A1CA 1UURA 2CBLA 1D4WA 2B3OA 5J3XA 1LCKA 2AOBA 3GQIB 1OPLA 3OB1B 1NZLA 2EL8A 4K2RA 1BFJA 4H34A 5DC9A 1JU5A 4LUEA 1O4MA 1AD5A 1PICA 1O47A 1O4OA 1GRIA 1O4IA 1RPYA 3PQZA 5EG3B 3IN8A 1FYRA 4K45A 3VS5A 5EEQA 1LKLA 1R1QA 1O45A 1QADA 2ECDA 3EACA 3HIZB 2FO0A 1LUMA 4LUDA 2Y1MA 1AYDA 4FL2A 1BM2A 1FHSA 2L6KA 2CI9A 4QSYA 3S8LA 5AULA 3UF4A 1H9OA 3HCKA 2HUWA 1OO4A 4TZIA 3CXLA 3PSKA 1IS0A 5IBSA 1LUKA 4OHLA 1O46A 5KAZA 1AOUF 2RSYA 1F1WA 3MAZA 2XP1A 4DGPA 1A08A 1O49A 2FCIA 3OB2B 2KK6A 1X27A 5DF6A 3NHNA 2ETZA 1D4TA 1OPKA 3BUWB 5BO4A 1G83A 3VS0A 1SHAA 2JYQA 1O4AA 1O4LA 3GXWA 1MILA 5EHRA 1O44A 2QMSA 1D1ZA 1O4NA 2MQIA 2HDXA 4U17A 1X6CA 1R1PA 2H46E 2LQWA 2GE9A 4XZ1A 2BBUA 2PTKA 3S9KA 1BLJA 2C0IA 2K7AB 2VIFA 2C9WA 1O43A 1UUSA 2LQNA 1O41A 2Y1NA 3MXCA 2OZOA 3US4A 1A1AA 3CWGA 2DM0A 4OHDA 3HHMB 1YVHA 1KSWA 1MW4A 5HKWA 3GXXA 4JE4A 1A1EA 3VGOA 3VS7A 1O48A 4ROJA 2H5KA 3VRYA 1Z3KA 1O4KA 3BUOB 1AB2A 1OO3A 1F2FA 4U1PA 2MC1A 2C0OA 4K44A 1AYBA 2PLDA 2RORA 4L1BB 3VRZA 2LNWA 1O4CA 3PS5A 1A07A 1O4BA 2YU7A 3C7IA 5EELA 1HCSB 4OHIA 1BMBA 1QG1E 2SRCA 1WQUA 4JEGA 4K11A 1CWDL 2CS0A 4P9VA 2Y3AB 1BHHB 1BLKA 2IZVA 2LNXA 4M4ZA 2DLZA 4EIHA 2AOAA 1KA6A 3BUMB 1SPSA 1A09A 2MK2A 3UYOA 2IUGA 5IBMA 4OHHA 4F5AA 2KNOA 4NWGA 1LUNA 4X6SA 2PLEA 5CDWA 2CI8A 4OHEA 2ABLA 3K2MA 1FBVA 1FU6A 3TKZA 3OV1A 4H1OA 2YSXA 1SPRA 2GSBA 2RMXA 2HDVA 1CWEA 1O4EA 5AXIA 2L4KA 4GWFA 1TZEE 1M27A 3VRQA 2SHPA 1NRVA 3TL0A 4GPLB 3MXYA 2EOBA 2OQ1A 3PSJA 2CR4A 3VS1A 1BHFA 2MRKA 1ZFPE 1JWOA 2AUGA 2DLYA 2K79B 1BKMA 1P13A 1Y57A 1XA6A 1QCFA 1CSYA 3WA4A 4A4BA 1AOTF 1KC2A 1BF5A 1LUIA 3VROA 3VRPA 1O42A 2L3TA 2CRHA 3VS4A 1SKJA 2PNAA 1A81A 3M7FA 3IMJA 1FMKA 3PFVA 2EYVA 1RQQC 1SHBA 2EO6A 4D8KA 3VRRA 5DC0B 2HMHA 2RVFA 1JYRA 4XZ0A 4A4CA 1M61A 5D0JA 2EKXA 1FU5A 1JYUA 1LKKA 3N7YA 1YVLA 1O4HA 3KFJA 1LCJA 2H8HA 4FL3A 1O4PA 3BKBA 2CIAA 5HKYA 4P9ZA 2PNBA 3N8MA 5EHPA 4NWFA 1Y1UA 5GJIA 1TCEA 1RJAA 1O4GA 1CJ1A 4JGHA 4WWQA 2EYZA 3OVEA 1A1BA 5GJHA 1BKLA 1I3ZA 2MRJA 2C0TA 3QWXX 1O4DA 1CSZA 3BUNB 2EU0A 1GHUA 1BHHA 4E93A 3EAZA 1O4FA 3VS2A 1NZVA 3VS6A 4EY0A 2DCRA 3PLFB 3VS3A 1SHDA 2DX0A 3BUXB 4FBNA 3S8NA 1IJRA 3CBLA 3OP0A 4F59A 1HCTB 5HKZA 4F5BA 4DGXA 1BG1A 2HCKA 1FBZA 3ZNIA 2IUHA 3VRNA 1R1SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GL9 E;  1JYQ A;  1B47 A;  1O4R A;  2EYY A;  1O4J A;  3IMD A;  1BFI A;  3T04 A;  4E68 A;  1K9A A;  3N84 A;  3S8O A;  2DVJ A;  3PJP A;  3IN7 A;  2EO3 A;  2LCT A;  5DC4 A;  5I6V A;  1X0N A;  3CD3 A;  1AYA A;  2IUI A;  1KA7 A;  3QWY A;  1AYC A;  1O4Q A;  1A1C A;  1UUR A;  2CBL A;  1D4W A;  2B3O A;  5J3X A;  1LCK A;  2AOB A;  3GQI B;  1OPL A;  3OB1 B;  1NZL A;  2EL8 A;  4K2R A;  1BFJ A;  4H34 A;  5DC9 A;  1JU5 A;  4LUE A;  1O4M A;  1AD5 A;  1PIC A;  1O47 A;  1O4O A;  1GRI A;  1O4I A;  1RPY A;  3PQZ A;  5EG3 B;  3IN8 A;  1FYR A;  4K45 A;  3VS5 A;  5EEQ A;  1LKL A;  1R1Q A;  1O45 A;  1QAD A;  2ECD A;  3EAC A;  3HIZ B;  2FO0 A;  1LUM A;  4LUD A;  2Y1M A;  1AYD A;  4FL2 A;  1BM2 A;  1FHS A;  2L6K A;  2CI9 A;  4QSY A;  3S8L A;  5AUL A;  3UF4 A;  1H9O A;  3HCK A;  2HUW A;  1OO4 A;  4TZI A;  3CXL A;  3PSK A;  1IS0 A;  5IBS A;  1LUK A;  4OHL A;  1O46 A;  5KAZ A;  1AOU F;  2RSY A;  1F1W A;  3MAZ A;  2XP1 A;  4DGP A;  1A08 A;  1O49 A;  2FCI A;  3OB2 B;  2KK6 A;  1X27 A;  5DF6 A;  3NHN A;  2ETZ A;  1D4T A;  1OPK A;  3BUW B;  5BO4 A;  1G83 A;  3VS0 A;  1SHA A;  2JYQ A;  1O4A A;  1O4L A;  3GXW A;  1MIL A;  5EHR A;  1O44 A;  2QMS A;  1D1Z A;  1O4N A;  2MQI A;  2HDX A;  4U17 A;  1X6C A;  1R1P A;  2H46 E;  2LQW A;  2GE9 A;  4XZ1 A;  2BBU A;  2PTK A;  3S9K A;  1BLJ A;  2C0I A;  2K7A B;  2VIF A;  2C9W A;  1O43 A;  1UUS A;  2LQN A;  1O41 A;  2Y1N A;  3MXC A;  2OZO A;  3US4 A;  1A1A A;  3CWG A;  2DM0 A;  4OHD A;  3HHM B;  1YVH A;  1KSW A;  1MW4 A;  5HKW A;  3GXX A;  4JE4 A;  1A1E A;  3VGO A;  3VS7 A;  1O48 A;  4ROJ A;  2H5K A;  3VRY A;  1Z3K A;  1O4K A;  3BUO B;  1AB2 A;  1OO3 A;  1F2F A;  4U1P A;  2MC1 A;  2C0O A;  4K44 A;  1AYB A;  2PLD A;  2ROR A;  4L1B B;  3VRZ A;  2LNW A;  1O4C A;  3PS5 A;  1A07 A;  1O4B A;  2YU7 A;  3C7I A;  5EEL A;  1HCS B;  4OHI A;  1BMB A;  1QG1 E;  2SRC A;  1WQU A;  4JEG A;  4K11 A;  1CWD L;  2CS0 A;  4P9V A;  2Y3A B;  1BHH B;  1BLK A;  2IZV A;  2LNX A;  4M4Z A;  2DLZ A;  4EIH A;  2AOA A;  1KA6 A;  3BUM B;  1SPS A;  1A09 A;  2MK2 A;  3UYO A;  2IUG A;  5IBM A;  4OHH A;  4F5A A;  2KNO A;  4NWG A;  1LUN A;  4X6S A;  2PLE A;  5CDW A;  2CI8 A;  4OHE A;  2ABL A;  3K2M A;  1FBV A;  1FU6 A;  3TKZ A;  3OV1 A;  4H1O A;  2YSX A;  1SPR A;  2GSB A;  2RMX A;  2HDV A;  1CWE A;  1O4E A;  5AXI A;  2L4K A;  4GWF A;  1TZE E;  1M27 A;  3VRQ A;  2SHP A;  1NRV A;  3TL0 A;  4GPL B;  3MXY A;  2EOB A;  2OQ1 A;  3PSJ A;  2CR4 A;  3VS1 A;  1BHF A;  2MRK A;  1ZFP E;  1JWO A;  2AUG A;  2DLY A;  2K79 B;  1BKM A;  1P13 A;  1Y57 A;  1XA6 A;  1QCF A;  1CSY A;  3WA4 A;  4A4B A;  1AOT F;  1KC2 A;  1BF5 A;  1LUI A;  3VRO A;  3VRP A;  1O42 A;  2L3T A;  2CRH A;  3VS4 A;  1SKJ A;  2PNA A;  1A81 A;  3M7F A;  3IMJ A;  1FMK A;  3PFV A;  2EYV A;  1RQQ C;  1SHB A;  2EO6 A;  4D8K A;  3VRR A;  5DC0 B;  2HMH A;  2RVF A;  1JYR A;  4XZ0 A;  4A4C A;  1M61 A;  5D0J A;  2EKX A;  1FU5 A;  1JYU A;  1LKK A;  3N7Y A;  1YVL A;  1O4H A;  3KFJ A;  1LCJ A;  2H8H A;  4FL3 A;  1O4P A;  3BKB A;  2CIA A;  5HKY A;  4P9Z A;  2PNB A;  3N8M A;  5EHP A;  4NWF A;  1Y1U A;  5GJI A;  1TCE A;  1RJA A;  1O4G A;  1CJ1 A;  4JGH A;  4WWQ A;  2EYZ A;  3OVE A;  1A1B A;  5GJH A;  1BKL A;  1I3Z A;  2MRJ A;  2C0T A;  3QWX X;  1O4D A;  1CSZ A;  3BUN B;  2EU0 A;  1GHU A;  1BHH A;  4E93 A;  3EAZ A;  1O4F A;  3VS2 A;  1NZV A;  3VS6 A;  4EY0 A;  2DCR A;  3PLF B;  3VS3 A;  1SHD A;  2DX0 A;  3BUX B;  4FBN A;  3S8N A;  1IJR A;  3CBL A;  3OP0 A;  4F59 A;  1HCT B;  5HKZ A;  4F5B A;  4DGX A;  1BG1 A;  2HCK A;  1FBZ A;  3ZNI A;  2IUH A;  3VRN A;  1R1S A; 
#chains in the Genus database with same CATH topology
 4GL9 E;  1JYQ A;  1B47 A;  1O4R A;  2EYY A;  1O4J A;  3IMD A;  1BFI A;  3T04 A;  4E68 A;  1K9A A;  3N84 A;  3S8O A;  2DVJ A;  3PJP A;  3IN7 A;  2EO3 A;  2LCT A;  5DC4 A;  5I6V A;  1X0N A;  3CD3 A;  1AYA A;  2IUI A;  1KA7 A;  3QWY A;  1AYC A;  1O4Q A;  1A1C A;  1UUR A;  2CBL A;  1D4W A;  2B3O A;  5J3X A;  1LCK A;  2AOB A;  3GQI B;  1OPL A;  3OB1 B;  1NZL A;  2EL8 A;  4K2R A;  1BFJ A;  4H34 A;  5DC9 A;  1JU5 A;  4LUE A;  1O4M A;  1AD5 A;  1PIC A;  1O47 A;  1O4O A;  1GRI A;  1O4I A;  1RPY A;  3PQZ A;  5EG3 B;  3IN8 A;  1FYR A;  4K45 A;  3VS5 A;  5EEQ A;  1LKL A;  1R1Q A;  1O45 A;  1QAD A;  2ECD A;  3EAC A;  3HIZ B;  2FO0 A;  1LUM A;  4LUD A;  2Y1M A;  1AYD A;  4FL2 A;  1BM2 A;  1FHS A;  2L6K A;  2CI9 A;  4QSY A;  3S8L A;  5AUL A;  3UF4 A;  1H9O A;  3HCK A;  2HUW A;  1OO4 A;  4TZI A;  3CXL A;  3PSK A;  1IS0 A;  5IBS A;  1LUK A;  4OHL A;  1O46 A;  5KAZ A;  1AOU F;  2RSY A;  1F1W A;  3MAZ A;  2XP1 A;  4DGP A;  1A08 A;  1O49 A;  2FCI A;  3OB2 B;  2KGY A;  2KK6 A;  1X27 A;  5DF6 A;  3NHN A;  2ETZ A;  1D4T A;  1OPK A;  3BUW B;  5BO4 A;  1G83 A;  3VS0 A;  1SHA A;  2JYQ A;  1O4A A;  1O4L A;  3GXW A;  1MIL A;  5EHR A;  1O44 A;  2QMS A;  1D1Z A;  1O4N A;  2MQI A;  2HDX A;  4U17 A;  1X6C A;  1R1P A;  2H46 E;  2LQW A;  2GE9 A;  4XZ1 A;  2BBU A;  2PTK A;  3S9K A;  1BLJ A;  2C0I A;  2K7A B;  2VIF A;  2C9W A;  1O43 A;  1UUS A;  2LQN A;  1O41 A;  2Y1N A;  3MXC A;  2OZO A;  3US4 A;  1A1A A;  3CWG A;  2DM0 A;  4OHD A;  3HHM B;  1YVH A;  1KSW A;  1MW4 A;  5HKW A;  3GXX A;  4JE4 A;  1A1E A;  3VGO A;  3VS7 A;  1O48 A;  4ROJ A;  2H5K A;  3VRY A;  1Z3K A;  1O4K A;  3BUO B;  1AB2 A;  1OO3 A;  1F2F A;  3K2T A;  4U1P A;  2MC1 A;  2C0O A;  4K44 A;  1AYB A;  2PLD A;  2ROR A;  4L1B B;  3VRZ A;  2LNW A;  1O4C A;  3PS5 A;  1A07 A;  1O4B A;  2YU7 A;  3C7I A;  5EEL A;  1HCS B;  4OHI A;  1BMB A;  1QG1 E;  2SRC A;  1WQU A;  4JEG A;  4K11 A;  1CWD L;  2CS0 A;  4P9V A;  2Y3A B;  1BHH B;  1BLK A;  2IZV A;  2LNX A;  4M4Z A;  2DLZ A;  4EIH A;  2AOA A;  1KA6 A;  3BUM B;  1SPS A;  1A09 A;  2MK2 A;  3UYO A;  2IUG A;  5IBM A;  4OHH A;  4F5A A;  2KNO A;  4NWG A;  1LUN A;  4X6S A;  2PLE A;  5CDW A;  2CI8 A;  4OHE A;  2ABL A;  3K2M A;  1FBV A;  1FU6 A;  3TKZ A;  3OV1 A;  4H1O A;  2YSX A;  1SPR A;  2GSB A;  2RMX A;  2HDV A;  1CWE A;  1O4E A;  5AXI A;  2L4K A;  4GWF A;  1TZE E;  1M27 A;  3VRQ A;  2SHP A;  1NRV A;  3TL0 A;  4GPL B;  3MXY A;  2EOB A;  2OQ1 A;  3PSJ A;  2CR4 A;  3VS1 A;  1BHF A;  2MRK A;  1ZFP E;  1JWO A;  2AUG A;  2DLY A;  2K79 B;  1BKM A;  1P13 A;  1Y57 A;  1XA6 A;  1QCF A;  1CSY A;  3WA4 A;  4A4B A;  1AOT F;  1KC2 A;  1BF5 A;  1LUI A;  3VRO A;  3VRP A;  1O42 A;  2L3T A;  2CRH A;  3VS4 A;  1SKJ A;  2PNA A;  1A81 A;  3M7F A;  3IMJ A;  1FMK A;  3PFV A;  2EYV A;  1RQQ C;  1SHB A;  2EO6 A;  4D8K A;  3VRR A;  5DC0 B;  2HMH A;  2RVF A;  1JYR A;  4XZ0 A;  4A4C A;  1M61 A;  5D0J A;  2EKX A;  3LYV A;  1FU5 A;  1JYU A;  1LKK A;  3N7Y A;  1YVL A;  1O4H A;  3KFJ A;  1LCJ A;  2H8H A;  4FL3 A;  1O4P A;  3BKB A;  2CIA A;  5HKY A;  4P9Z A;  2PNB A;  3N8M A;  5EHP A;  4NWF A;  1Y1U A;  5GJI A;  1TCE A;  1RJA A;  1O4G A;  1CJ1 A;  4JGH A;  4WWQ A;  2EYZ A;  3OVE A;  1A1B A;  5GJH A;  1BKL A;  1I3Z A;  2MRJ A;  2C0T A;  3QWX X;  1O4D A;  1CSZ A;  3BUN B;  2EU0 A;  1GHU A;  1BHH A;  4E93 A;  3EAZ A;  1O4F A;  3VS2 A;  1NZV A;  3VS6 A;  4EY0 A;  2DCR A;  3PLF B;  3VS3 A;  1SHD A;  2DX0 A;  2LRA A;  3BUX B;  4FBN A;  3S8N A;  1IJR A;  3CBL A;  3OP0 A;  4F59 A;  1HCT B;  5HKZ A;  4F5B A;  4DGX A;  1BG1 A;  2HCK A;  1FBZ A;  3ZNI A;  2IUH A;  3VRN A;  1R1S A; 
#chains in the Genus database with same CATH homology
 4GL9 E;  1JYQ A;  1B47 A;  1O4R A;  2EYY A;  1O4J A;  3IMD A;  1BFI A;  3T04 A;  4E68 A;  1K9A A;  3N84 A;  3S8O A;  2DVJ A;  3PJP A;  3IN7 A;  2EO3 A;  2LCT A;  5DC4 A;  5I6V A;  1X0N A;  3CD3 A;  1AYA A;  2IUI A;  1KA7 A;  3QWY A;  1AYC A;  1O4Q A;  1A1C A;  1UUR A;  2CBL A;  1D4W A;  2B3O A;  5J3X A;  1LCK A;  2AOB A;  3GQI B;  1OPL A;  3OB1 B;  1NZL A;  2EL8 A;  4K2R A;  1BFJ A;  4H34 A;  5DC9 A;  1JU5 A;  4LUE A;  1O4M A;  1AD5 A;  1PIC A;  1O47 A;  1O4O A;  1GRI A;  1O4I A;  1RPY A;  3PQZ A;  5EG3 B;  3IN8 A;  1FYR A;  4K45 A;  3VS5 A;  5EEQ A;  1LKL A;  1R1Q A;  1O45 A;  1QAD A;  2ECD A;  3EAC A;  3HIZ B;  2FO0 A;  1LUM A;  4LUD A;  2Y1M A;  1AYD A;  4FL2 A;  1BM2 A;  1FHS A;  2L6K A;  2CI9 A;  4QSY A;  3S8L A;  5AUL A;  3UF4 A;  1H9O A;  3HCK A;  2HUW A;  1OO4 A;  4TZI A;  3CXL A;  3PSK A;  1IS0 A;  5IBS A;  1LUK A;  4OHL A;  1O46 A;  5KAZ A;  1AOU F;  2RSY A;  1F1W A;  3MAZ A;  2XP1 A;  4DGP A;  1A08 A;  1O49 A;  2FCI A;  3OB2 B;  2KK6 A;  1X27 A;  5DF6 A;  3NHN A;  2ETZ A;  1D4T A;  1OPK A;  3BUW B;  5BO4 A;  1G83 A;  3VS0 A;  1SHA A;  2JYQ A;  1O4A A;  1O4L A;  3GXW A;  1MIL A;  5EHR A;  1O44 A;  2QMS A;  1D1Z A;  1O4N A;  2MQI A;  2HDX A;  4U17 A;  1X6C A;  1R1P A;  2H46 E;  2LQW A;  2GE9 A;  4XZ1 A;  2BBU A;  2PTK A;  3S9K A;  1BLJ A;  2C0I A;  2K7A B;  2VIF A;  2C9W A;  1O43 A;  1UUS A;  2LQN A;  1O41 A;  2Y1N A;  3MXC A;  2OZO A;  3US4 A;  1A1A A;  3CWG A;  2DM0 A;  4OHD A;  3HHM B;  1YVH A;  1KSW A;  1MW4 A;  5HKW A;  3GXX A;  4JE4 A;  1A1E A;  3VGO A;  3VS7 A;  1O48 A;  4ROJ A;  2H5K A;  3VRY A;  1Z3K A;  1O4K A;  3BUO B;  1AB2 A;  1OO3 A;  1F2F A;  4U1P A;  2MC1 A;  2C0O A;  4K44 A;  1AYB A;  2PLD A;  2ROR A;  4L1B B;  3VRZ A;  2LNW A;  1O4C A;  3PS5 A;  1A07 A;  1O4B A;  2YU7 A;  3C7I A;  5EEL A;  1HCS B;  4OHI A;  1BMB A;  1QG1 E;  2SRC A;  1WQU A;  4JEG A;  4K11 A;  1CWD L;  2CS0 A;  4P9V A;  2Y3A B;  1BHH B;  1BLK A;  2IZV A;  2LNX A;  4M4Z A;  2DLZ A;  4EIH A;  2AOA A;  1KA6 A;  3BUM B;  1SPS A;  1A09 A;  2MK2 A;  3UYO A;  2IUG A;  5IBM A;  4OHH A;  4F5A A;  2KNO A;  4NWG A;  1LUN A;  4X6S A;  2PLE A;  5CDW A;  2CI8 A;  4OHE A;  2ABL A;  3K2M A;  1FBV A;  1FU6 A;  3TKZ A;  3OV1 A;  4H1O A;  2YSX A;  1SPR A;  2GSB A;  2RMX A;  2HDV A;  1CWE A;  1O4E A;  5AXI A;  2L4K A;  4GWF A;  1TZE E;  1M27 A;  3VRQ A;  2SHP A;  1NRV A;  3TL0 A;  4GPL B;  3MXY A;  2EOB A;  2OQ1 A;  3PSJ A;  2CR4 A;  3VS1 A;  1BHF A;  2MRK A;  1ZFP E;  1JWO A;  2AUG A;  2DLY A;  2K79 B;  1BKM A;  1P13 A;  1Y57 A;  1XA6 A;  1QCF A;  1CSY A;  3WA4 A;  4A4B A;  1AOT F;  1KC2 A;  1BF5 A;  1LUI A;  3VRO A;  3VRP A;  1O42 A;  2L3T A;  2CRH A;  3VS4 A;  1SKJ A;  2PNA A;  1A81 A;  3M7F A;  3IMJ A;  1FMK A;  3PFV A;  2EYV A;  1RQQ C;  1SHB A;  2EO6 A;  4D8K A;  3VRR A;  5DC0 B;  2HMH A;  2RVF A;  1JYR A;  4XZ0 A;  4A4C A;  1M61 A;  5D0J A;  2EKX A;  1FU5 A;  1JYU A;  1LKK A;  3N7Y A;  1YVL A;  1O4H A;  3KFJ A;  1LCJ A;  2H8H A;  4FL3 A;  1O4P A;  3BKB A;  2CIA A;  5HKY A;  4P9Z A;  2PNB A;  3N8M A;  5EHP A;  4NWF A;  1Y1U A;  5GJI A;  1TCE A;  1RJA A;  1O4G A;  1CJ1 A;  4JGH A;  4WWQ A;  2EYZ A;  3OVE A;  1A1B A;  5GJH A;  1BKL A;  1I3Z A;  2MRJ A;  2C0T A;  3QWX X;  1O4D A;  1CSZ A;  3BUN B;  2EU0 A;  1GHU A;  1BHH A;  4E93 A;  3EAZ A;  1O4F A;  3VS2 A;  1NZV A;  3VS6 A;  4EY0 A;  2DCR A;  3PLF B;  3VS3 A;  1SHD A;  2DX0 A;  3BUX B;  4FBN A;  3S8N A;  1IJR A;  3CBL A;  3OP0 A;  4F59 A;  1HCT B;  5HKZ A;  4F5B A;  4DGX A;  1BG1 A;  2HCK A;  1FBZ A;  3ZNI A;  2IUH A;  3VRN A;  1R1S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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