1O4LA

Crystal structure of sh2 in complex with fragment2.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4lA00
4JEGA 1CJ1A 1FBVA 3HIZB 4H34A 2BBUA 2PLEA 3VRYA 2EL8A 4LUDA 4JE4A 2DLYA 1JYUA 3GXWA 3BKBA 4XZ0A 2XP1A 2YU7A 3T04A 1UURA 1ZFPE 3VS7A 3IMDA 3IMJA 5EHPA 5EG3B 3VS4A 2B3OA 4L1BB 2RSYA 4K44A 1RJAA 3C7IA 2L4KA 1D4TA 1FYRA 1JYRA 3BUOB 1LKKA 5CDWA 2CBLA 4FBNA 4JGHA 1O43A 2CIAA 3PSJA 1O41A 1UUSA 3CXLA 1O4CA 1O49A 1A1BA 1O4KA 1O4HA 5I6VA 2IUGA 3QWYA 4NWGA 3EAZA 2VIFA 3QWXX 3PLFB 2YSXA 2MRJA 1F1WA 1O4NA 2H46E 3M7FA 1SKJA 1R1PA 1GHUA 1FU6A 1QG1E 1O4EA 1AYDA 1LCKA 4P9ZA 4QSYA 3GQIB 5EELA 1SHBA 1BLKA 2DLZA 5KAZA 1JU5A 2ABLA 4P9VA 1AB2A 1MILA 2JYQA 5GJIA 2DM0A 1LUNA 1R1QA 1SHAA 2IUIA 2K79B 3MXCA 3BUWB 4LUEA 4EIHA 1M27A 4OHEA 3CD3A 2HDVA 1O4FA 2IZVA 2Y3AB 1KA6A 3VRRA 2MK2A 1O4QA 1FHSA 1M61A 3PJPA 1SPRA 4OHIA 1AOUF 1A1EA 3VRZA 1O42A 4X6SA 1A09A 1OO4A 3EACA 2HCKA 5DC0B 1O4MA 2EO3A 1WQUA 3VGOA 2DCRA 2MC1A 2LQWA 1O4PA 2L6KA 5IBSA 2LCTA 1QCFA 1RPYA 1LCJA 3N84A 2RVFA 1NZVA 3PQZA 2Y1NA 4OHDA 1HCSB 3VS1A 1O44A 4F5AA 2CI9A 2EYZA 1O4LA 2SHPA 5D0JA 1I3ZA 1X0NA 3KFJA 2EKXA 3IN8A 5DC4A 2EYVA 3NHNA 1K9AA 3UF4A 2GSBA 5AXIA 4E93A 3TL0A 4ROJA 2CI8A 2CS0A 2RORA 1O48A 4EY0A 4GPLB 1AOTF 2L3TA 3CBLA 1G83A 1FU5A 1LUIA 1CWDL 2CRHA 4A4CA 4H1OA 1FBZA 4E68A 2C0TA 3K2MA 3WA4A 3MXYA 3PFVA 1OPLA 4FL3A 1KSWA 1TCEA 1OO3A 1O45A 1JWOA 3OB2B 4DGPA 3BUXB 4OHLA 2CR4A 4XZ1A 1BFJA 5J3XA 1BKMA 1O4IA 4K2RA 1Z3KA 2RMXA 1NRVA 2QMSA 4DGXA 1X27A 1YVLA 3OP0A 3PSKA 4U17A 2MQIA 1BKLA 1O4OA 1CSYA 1YVHA 3TKZA 4M4ZA 4K11A 2EO6A 2LNXA 1BF5A 4FL2A 2AUGA 1Y1UA 4GL9E 1BM2A 1A08A 3VRNA 2EYYA 1O4BA 2HMHA 2OZOA 1O4GA 1A07A 3ZNIA 1KA7A 1BHHA 3US4A 2PNBA 2ETZA 1CSZA 4OHHA 2AOBA 2ECDA 3S8OA 1O4AA 1SPSA 3BUNB 1FMKA 4WWQA 1O4DA 1X6CA 4TZIA 4A4BA 2C0IA 1A81A 2EU0A 5BO4A 1AYAA 1H9OA 2PLDA 3VS5A 2MRKA 1RQQC 1AYCA 2H5KA 4K45A 3VRPA 1IJRA 3N7YA 1B47A 1BMBA 3IN7A 5DC9A 2C0OA 3N8MA 4NWFA 1PICA 1D4WA 1LUKA 1LKLA 3HCKA 2Y1MA 5DF6A 1O47A 2LNWA 1NZLA 3S8LA 1LUMA 3VRQA 3GXXA 3VS0A 4D8KA 2GE9A 1BLJA 2KK6A 1CWEA 1BHFA 2FCIA 2H8HA 2AOAA 1MW4A 5EHRA 2OQ1A 3MAZA 1HCTB 3VS2A 1O4RA 3S9KA 1A1AA 1AYBA 4F5BA 3VS3A 3VS6A 3OVEA 1KC2A 2DX0A 4U1PA 3BUMB 2PTKA 1QADA 3VROA 1F2FA 5IBMA 3HHMB 1GRIA 1BHHB 1D1ZA 5AULA 2SRCA 2DVJA 2PNAA 2LQNA 1O46A 1AD5A 3OB1B 2EOBA 1BG1A 2HUWA 2KNOA 1XA6A 1OPKA 3S8NA 3OV1A 1A1CA 2C9WA 1SHDA 5HKZA 1R1SA 1JYQA 1Y57A 5HKYA 2HDXA 1BFIA 1TZEE 2IUHA 2K7AB 3UYOA 1IS0A 4GWFA 2FO0A 3PS5A 5HKWA 1O4JA 5EEQA 1P13A 4F59A 5GJHA 3CWGA
chains in the Genus database with same CATH superfamily
4JEGA 1CJ1A 1FBVA 3HIZB 4H34A 2BBUA 2PLEA 3VRYA 2EL8A 4LUDA 4JE4A 2DLYA 1JYUA 3GXWA 3BKBA 4XZ0A 2XP1A 2YU7A 3T04A 1UURA 1ZFPE 3LYVA 3VS7A 3IMDA 3IMJA 5EHPA 5EG3B 3VS4A 2B3OA 4L1BB 2RSYA 4K44A 1RJAA 3C7IA 2L4KA 1D4TA 1FYRA 1JYRA 3BUOB 1LKKA 5CDWA 2CBLA 4FBNA 4JGHA 1O43A 2CIAA 3PSJA 1O41A 1UUSA 3CXLA 1O4CA 1O49A 1A1BA 1O4KA 1O4HA 5I6VA 2IUGA 3QWYA 4NWGA 3EAZA 2VIFA 3QWXX 3PLFB 2YSXA 2MRJA 1F1WA 1O4NA 2H46E 3M7FA 1SKJA 1R1PA 1GHUA 1FU6A 1QG1E 1O4EA 1AYDA 1LCKA 4P9ZA 4QSYA 3GQIB 5EELA 1SHBA 1BLKA 2DLZA 5KAZA 1JU5A 2ABLA 4P9VA 1AB2A 1MILA 2KGYA 2JYQA 5GJIA 2DM0A 1LUNA 1R1QA 1SHAA 2IUIA 2K79B 3MXCA 3BUWB 4LUEA 4EIHA 1M27A 4OHEA 3CD3A 2HDVA 1O4FA 2IZVA 2Y3AB 1KA6A 3VRRA 2MK2A 1O4QA 1FHSA 1M61A 3PJPA 1SPRA 4OHIA 1AOUF 1A1EA 3VRZA 1O42A 4X6SA 1A09A 1OO4A 2LRAA 3EACA 2HCKA 5DC0B 1O4MA 2EO3A 1WQUA 3VGOA 2DCRA 2MC1A 2LQWA 1O4PA 2L6KA 5IBSA 2LCTA 1QCFA 1RPYA 1LCJA 3N84A 2RVFA 1NZVA 3PQZA 2Y1NA 4OHDA 1HCSB 3VS1A 1O44A 4F5AA 2CI9A 2EYZA 1O4LA 2SHPA 5D0JA 1I3ZA 1X0NA 3KFJA 2EKXA 3IN8A 5DC4A 2EYVA 3NHNA 1K9AA 3UF4A 2GSBA 5AXIA 4E93A 3TL0A 4ROJA 2CI8A 2CS0A 2RORA 1O48A 4EY0A 4GPLB 1AOTF 2L3TA 3CBLA 1G83A 1FU5A 1LUIA 1CWDL 2CRHA 4A4CA 4H1OA 1FBZA 4E68A 2C0TA 3K2MA 3WA4A 3MXYA 3PFVA 1OPLA 4FL3A 1KSWA 1TCEA 1OO3A 1O45A 1JWOA 3OB2B 4DGPA 3BUXB 4OHLA 2CR4A 4XZ1A 1BFJA 5J3XA 1BKMA 1O4IA 4K2RA 1Z3KA 2RMXA 1NRVA 2QMSA 4DGXA 1X27A 1YVLA 3OP0A 3PSKA 4U17A 2MQIA 1BKLA 1O4OA 1CSYA 1YVHA 3TKZA 4M4ZA 4K11A 2EO6A 2LNXA 1BF5A 4FL2A 2AUGA 1Y1UA 4GL9E 1BM2A 1A08A 3VRNA 2EYYA 1O4BA 2HMHA 2OZOA 1O4GA 1A07A 3ZNIA 1KA7A 1BHHA 3US4A 2PNBA 2ETZA 1CSZA 4OHHA 2AOBA 2ECDA 3S8OA 1O4AA 1SPSA 3BUNB 1FMKA 4WWQA 1O4DA 1X6CA 4TZIA 4A4BA 2C0IA 1A81A 2EU0A 5BO4A 1AYAA 1H9OA 2PLDA 3VS5A 2MRKA 1RQQC 1AYCA 2H5KA 4K45A 3VRPA 1IJRA 3N7YA 1B47A 1BMBA 3IN7A 5DC9A 2C0OA 3N8MA 4NWFA 1PICA 1D4WA 1LUKA 1LKLA 3HCKA 2Y1MA 5DF6A 1O47A 2LNWA 1NZLA 3S8LA 1LUMA 3VRQA 3GXXA 3VS0A 4D8KA 2GE9A 1BLJA 2KK6A 1CWEA 1BHFA 2FCIA 2H8HA 2AOAA 1MW4A 5EHRA 2OQ1A 3MAZA 1HCTB 3VS2A 1O4RA 3S9KA 1A1AA 1AYBA 4F5BA 3VS3A 3VS6A 3OVEA 1KC2A 2DX0A 4U1PA 3BUMB 2PTKA 1QADA 3VROA 1F2FA 5IBMA 3HHMB 1GRIA 1BHHB 1D1ZA 5AULA 2SRCA 2DVJA 2PNAA 2LQNA 1O46A 3K2TA 1AD5A 3OB1B 2EOBA 1BG1A 2HUWA 2KNOA 1XA6A 1OPKA 3S8NA 3OV1A 1A1CA 2C9WA 1SHDA 5HKZA 1R1SA 1JYQA 1Y57A 5HKYA 2HDXA 1BFIA 1TZEE 2IUHA 2K7AB 3UYOA 1IS0A 4GWFA 2FO0A 3PS5A 5HKWA 1O4JA 5EEQA 1P13A 4F59A 5GJHA 3CWGA
chains in the Genus database with same CATH topology
4JEGA 1CJ1A 1FBVA 3HIZB 4H34A 2BBUA 2PLEA 3VRYA 2EL8A 4LUDA 4JE4A 2DLYA 1JYUA 3GXWA 3BKBA 4XZ0A 2XP1A 2YU7A 3T04A 1UURA 1ZFPE 3VS7A 3IMDA 3IMJA 5EHPA 5EG3B 3VS4A 2B3OA 4L1BB 2RSYA 4K44A 1RJAA 3C7IA 2L4KA 1D4TA 1FYRA 1JYRA 3BUOB 1LKKA 5CDWA 2CBLA 4FBNA 4JGHA 1O43A 2CIAA 3PSJA 1O41A 1UUSA 3CXLA 1O4CA 1O49A 1A1BA 1O4KA 1O4HA 5I6VA 2IUGA 3QWYA 4NWGA 3EAZA 2VIFA 3QWXX 3PLFB 2YSXA 2MRJA 1F1WA 1O4NA 2H46E 3M7FA 1SKJA 1R1PA 1GHUA 1FU6A 1QG1E 1O4EA 1AYDA 1LCKA 4P9ZA 4QSYA 3GQIB 5EELA 1SHBA 1BLKA 2DLZA 5KAZA 1JU5A 2ABLA 4P9VA 1AB2A 1MILA 2JYQA 5GJIA 2DM0A 1LUNA 1R1QA 1SHAA 2IUIA 2K79B 3MXCA 3BUWB 4LUEA 4EIHA 1M27A 4OHEA 3CD3A 2HDVA 1O4FA 2IZVA 2Y3AB 1KA6A 3VRRA 2MK2A 1O4QA 1FHSA 1M61A 3PJPA 1SPRA 4OHIA 1AOUF 1A1EA 3VRZA 1O42A 4X6SA 1A09A 1OO4A 3EACA 2HCKA 5DC0B 1O4MA 2EO3A 1WQUA 3VGOA 2DCRA 2MC1A 2LQWA 1O4PA 2L6KA 5IBSA 2LCTA 1QCFA 1RPYA 1LCJA 3N84A 2RVFA 1NZVA 3PQZA 2Y1NA 4OHDA 1HCSB 3VS1A 1O44A 4F5AA 2CI9A 2EYZA 1O4LA 2SHPA 5D0JA 1I3ZA 1X0NA 3KFJA 2EKXA 3IN8A 5DC4A 2EYVA 3NHNA 1K9AA 3UF4A 2GSBA 5AXIA 4E93A 3TL0A 4ROJA 2CI8A 2CS0A 2RORA 1O48A 4EY0A 4GPLB 1AOTF 2L3TA 3CBLA 1G83A 1FU5A 1LUIA 1CWDL 2CRHA 4A4CA 4H1OA 1FBZA 4E68A 2C0TA 3K2MA 3WA4A 3MXYA 3PFVA 1OPLA 4FL3A 1KSWA 1TCEA 1OO3A 1O45A 1JWOA 3OB2B 4DGPA 3BUXB 4OHLA 2CR4A 4XZ1A 1BFJA 5J3XA 1BKMA 1O4IA 4K2RA 1Z3KA 2RMXA 1NRVA 2QMSA 4DGXA 1X27A 1YVLA 3OP0A 3PSKA 4U17A 2MQIA 1BKLA 1O4OA 1CSYA 1YVHA 3TKZA 4M4ZA 4K11A 2EO6A 2LNXA 1BF5A 4FL2A 2AUGA 1Y1UA 4GL9E 1BM2A 1A08A 3VRNA 2EYYA 1O4BA 2HMHA 2OZOA 1O4GA 1A07A 3ZNIA 1KA7A 1BHHA 3US4A 2PNBA 2ETZA 1CSZA 4OHHA 2AOBA 2ECDA 3S8OA 1O4AA 1SPSA 3BUNB 1FMKA 4WWQA 1O4DA 1X6CA 4TZIA 4A4BA 2C0IA 1A81A 2EU0A 5BO4A 1AYAA 1H9OA 2PLDA 3VS5A 2MRKA 1RQQC 1AYCA 2H5KA 4K45A 3VRPA 1IJRA 3N7YA 1B47A 1BMBA 3IN7A 5DC9A 2C0OA 3N8MA 4NWFA 1PICA 1D4WA 1LUKA 1LKLA 3HCKA 2Y1MA 5DF6A 1O47A 2LNWA 1NZLA 3S8LA 1LUMA 3VRQA 3GXXA 3VS0A 4D8KA 2GE9A 1BLJA 2KK6A 1CWEA 1BHFA 2FCIA 2H8HA 2AOAA 1MW4A 5EHRA 2OQ1A 3MAZA 1HCTB 3VS2A 1O4RA 3S9KA 1A1AA 1AYBA 4F5BA 3VS3A 3VS6A 3OVEA 1KC2A 2DX0A 4U1PA 3BUMB 2PTKA 1QADA 3VROA 1F2FA 5IBMA 3HHMB 1GRIA 1BHHB 1D1ZA 5AULA 2SRCA 2DVJA 2PNAA 2LQNA 1O46A 1AD5A 3OB1B 2EOBA 1BG1A 2HUWA 2KNOA 1XA6A 1OPKA 3S8NA 3OV1A 1A1CA 2C9WA 1SHDA 5HKZA 1R1SA 1JYQA 1Y57A 5HKYA 2HDXA 1BFIA 1TZEE 2IUHA 2K7AB 3UYOA 1IS0A 4GWFA 2FO0A 3PS5A 5HKWA 1O4JA 5EEQA 1P13A 4F59A 5GJHA 3CWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JEG A;  1CJ1 A;  1FBV A;  3HIZ B;  4H34 A;  2BBU A;  2PLE A;  3VRY A;  2EL8 A;  4LUD A;  4JE4 A;  2DLY A;  1JYU A;  3GXW A;  3BKB A;  4XZ0 A;  2XP1 A;  2YU7 A;  3T04 A;  1UUR A;  1ZFP E;  3VS7 A;  3IMD A;  3IMJ A;  5EHP A;  5EG3 B;  3VS4 A;  2B3O A;  4L1B B;  2RSY A;  4K44 A;  1RJA A;  3C7I A;  2L4K A;  1D4T A;  1FYR A;  1JYR A;  3BUO B;  1LKK A;  5CDW A;  2CBL A;  4FBN A;  4JGH A;  1O43 A;  2CIA A;  3PSJ A;  1O41 A;  1UUS A;  3CXL A;  1O4C A;  1O49 A;  1A1B A;  1O4K A;  1O4H A;  5I6V A;  2IUG A;  3QWY A;  4NWG A;  3EAZ A;  2VIF A;  3QWX X;  3PLF B;  2YSX A;  2MRJ A;  1F1W A;  1O4N A;  2H46 E;  3M7F A;  1SKJ A;  1R1P A;  1GHU A;  1FU6 A;  1QG1 E;  1O4E A;  1AYD A;  1LCK A;  4P9Z A;  4QSY A;  3GQI B;  5EEL A;  1SHB A;  1BLK A;  2DLZ A;  5KAZ A;  1JU5 A;  2ABL A;  4P9V A;  1AB2 A;  1MIL A;  2JYQ A;  5GJI A;  2DM0 A;  1LUN A;  1R1Q A;  1SHA A;  2IUI A;  2K79 B;  3MXC A;  3BUW B;  4LUE A;  4EIH A;  1M27 A;  4OHE A;  3CD3 A;  2HDV A;  1O4F A;  2IZV A;  2Y3A B;  1KA6 A;  3VRR A;  2MK2 A;  1O4Q A;  1FHS A;  1M61 A;  3PJP A;  1SPR A;  4OHI A;  1AOU F;  1A1E A;  3VRZ A;  1O42 A;  4X6S A;  1A09 A;  1OO4 A;  3EAC A;  2HCK A;  5DC0 B;  1O4M A;  2EO3 A;  1WQU A;  3VGO A;  2DCR A;  2MC1 A;  2LQW A;  1O4P A;  2L6K A;  5IBS A;  2LCT A;  1QCF A;  1RPY A;  1LCJ A;  3N84 A;  2RVF A;  1NZV A;  3PQZ A;  2Y1N A;  4OHD A;  1HCS B;  3VS1 A;  1O44 A;  4F5A A;  2CI9 A;  2EYZ A;  1O4L A;  2SHP A;  5D0J A;  1I3Z A;  1X0N A;  3KFJ A;  2EKX A;  3IN8 A;  5DC4 A;  2EYV A;  3NHN A;  1K9A A;  3UF4 A;  2GSB A;  5AXI A;  4E93 A;  3TL0 A;  4ROJ A;  2CI8 A;  2CS0 A;  2ROR A;  1O48 A;  4EY0 A;  4GPL B;  1AOT F;  2L3T A;  3CBL A;  1G83 A;  1FU5 A;  1LUI A;  1CWD L;  2CRH A;  4A4C A;  4H1O A;  1FBZ A;  4E68 A;  2C0T A;  3K2M A;  3WA4 A;  3MXY A;  3PFV A;  1OPL A;  4FL3 A;  1KSW A;  1TCE A;  1OO3 A;  1O45 A;  1JWO A;  3OB2 B;  4DGP A;  3BUX B;  4OHL A;  2CR4 A;  4XZ1 A;  1BFJ A;  5J3X A;  1BKM A;  1O4I A;  4K2R A;  1Z3K A;  2RMX A;  1NRV A;  2QMS A;  4DGX A;  1X27 A;  1YVL A;  3OP0 A;  3PSK A;  4U17 A;  2MQI A;  1BKL A;  1O4O A;  1CSY A;  1YVH A;  3TKZ A;  4M4Z A;  4K11 A;  2EO6 A;  2LNX A;  1BF5 A;  4FL2 A;  2AUG A;  1Y1U A;  4GL9 E;  1BM2 A;  1A08 A;  3VRN A;  2EYY A;  1O4B A;  2HMH A;  2OZO A;  1O4G A;  1A07 A;  3ZNI A;  1KA7 A;  1BHH A;  3US4 A;  2PNB A;  2ETZ A;  1CSZ A;  4OHH A;  2AOB A;  2ECD A;  3S8O A;  1O4A A;  1SPS A;  3BUN B;  1FMK A;  4WWQ A;  1O4D A;  1X6C A;  4TZI A;  4A4B A;  2C0I A;  1A81 A;  2EU0 A;  5BO4 A;  1AYA A;  1H9O A;  2PLD A;  3VS5 A;  2MRK A;  1RQQ C;  1AYC A;  2H5K A;  4K45 A;  3VRP A;  1IJR A;  3N7Y A;  1B47 A;  1BMB A;  3IN7 A;  5DC9 A;  2C0O A;  3N8M A;  4NWF A;  1PIC A;  1D4W A;  1LUK A;  1LKL A;  3HCK A;  2Y1M A;  5DF6 A;  1O47 A;  2LNW A;  1NZL A;  3S8L A;  1LUM A;  3VRQ A;  3GXX A;  3VS0 A;  4D8K A;  2GE9 A;  1BLJ A;  2KK6 A;  1CWE A;  1BHF A;  2FCI A;  2H8H A;  2AOA A;  1MW4 A;  5EHR A;  2OQ1 A;  3MAZ A;  1HCT B;  3VS2 A;  1O4R A;  3S9K A;  1A1A A;  1AYB A;  4F5B A;  3VS3 A;  3VS6 A;  3OVE A;  1KC2 A;  2DX0 A;  4U1P A;  3BUM B;  2PTK A;  1QAD A;  3VRO A;  1F2F A;  5IBM A;  3HHM B;  1GRI A;  1BHH B;  1D1Z A;  5AUL A;  2SRC A;  2DVJ A;  2PNA A;  2LQN A;  1O46 A;  1AD5 A;  3OB1 B;  2EOB A;  1BG1 A;  2HUW A;  2KNO A;  1XA6 A;  1OPK A;  3S8N A;  3OV1 A;  1A1C A;  2C9W A;  1SHD A;  5HKZ A;  1R1S A;  1JYQ A;  1Y57 A;  5HKY A;  2HDX A;  1BFI A;  1TZE E;  2IUH A;  2K7A B;  3UYO A;  1IS0 A;  4GWF A;  2FO0 A;  3PS5 A;  5HKW A;  1O4J A;  5EEQ A;  1P13 A;  4F59 A;  5GJH A;  3CWG A; 
#chains in the Genus database with same CATH topology
 4JEG A;  1CJ1 A;  1FBV A;  3HIZ B;  4H34 A;  2BBU A;  2PLE A;  3VRY A;  2EL8 A;  4LUD A;  4JE4 A;  2DLY A;  1JYU A;  3GXW A;  3BKB A;  4XZ0 A;  2XP1 A;  2YU7 A;  3T04 A;  1UUR A;  1ZFP E;  3LYV A;  3VS7 A;  3IMD A;  3IMJ A;  5EHP A;  5EG3 B;  3VS4 A;  2B3O A;  4L1B B;  2RSY A;  4K44 A;  1RJA A;  3C7I A;  2L4K A;  1D4T A;  1FYR A;  1JYR A;  3BUO B;  1LKK A;  5CDW A;  2CBL A;  4FBN A;  4JGH A;  1O43 A;  2CIA A;  3PSJ A;  1O41 A;  1UUS A;  3CXL A;  1O4C A;  1O49 A;  1A1B A;  1O4K A;  1O4H A;  5I6V A;  2IUG A;  3QWY A;  4NWG A;  3EAZ A;  2VIF A;  3QWX X;  3PLF B;  2YSX A;  2MRJ A;  1F1W A;  1O4N A;  2H46 E;  3M7F A;  1SKJ A;  1R1P A;  1GHU A;  1FU6 A;  1QG1 E;  1O4E A;  1AYD A;  1LCK A;  4P9Z A;  4QSY A;  3GQI B;  5EEL A;  1SHB A;  1BLK A;  2DLZ A;  5KAZ A;  1JU5 A;  2ABL A;  4P9V A;  1AB2 A;  1MIL A;  2KGY A;  2JYQ A;  5GJI A;  2DM0 A;  1LUN A;  1R1Q A;  1SHA A;  2IUI A;  2K79 B;  3MXC A;  3BUW B;  4LUE A;  4EIH A;  1M27 A;  4OHE A;  3CD3 A;  2HDV A;  1O4F A;  2IZV A;  2Y3A B;  1KA6 A;  3VRR A;  2MK2 A;  1O4Q A;  1FHS A;  1M61 A;  3PJP A;  1SPR A;  4OHI A;  1AOU F;  1A1E A;  3VRZ A;  1O42 A;  4X6S A;  1A09 A;  1OO4 A;  2LRA A;  3EAC A;  2HCK A;  5DC0 B;  1O4M A;  2EO3 A;  1WQU A;  3VGO A;  2DCR A;  2MC1 A;  2LQW A;  1O4P A;  2L6K A;  5IBS A;  2LCT A;  1QCF A;  1RPY A;  1LCJ A;  3N84 A;  2RVF A;  1NZV A;  3PQZ A;  2Y1N A;  4OHD A;  1HCS B;  3VS1 A;  1O44 A;  4F5A A;  2CI9 A;  2EYZ A;  1O4L A;  2SHP A;  5D0J A;  1I3Z A;  1X0N A;  3KFJ A;  2EKX A;  3IN8 A;  5DC4 A;  2EYV A;  3NHN A;  1K9A A;  3UF4 A;  2GSB A;  5AXI A;  4E93 A;  3TL0 A;  4ROJ A;  2CI8 A;  2CS0 A;  2ROR A;  1O48 A;  4EY0 A;  4GPL B;  1AOT F;  2L3T A;  3CBL A;  1G83 A;  1FU5 A;  1LUI A;  1CWD L;  2CRH A;  4A4C A;  4H1O A;  1FBZ A;  4E68 A;  2C0T A;  3K2M A;  3WA4 A;  3MXY A;  3PFV A;  1OPL A;  4FL3 A;  1KSW A;  1TCE A;  1OO3 A;  1O45 A;  1JWO A;  3OB2 B;  4DGP A;  3BUX B;  4OHL A;  2CR4 A;  4XZ1 A;  1BFJ A;  5J3X A;  1BKM A;  1O4I A;  4K2R A;  1Z3K A;  2RMX A;  1NRV A;  2QMS A;  4DGX A;  1X27 A;  1YVL A;  3OP0 A;  3PSK A;  4U17 A;  2MQI A;  1BKL A;  1O4O A;  1CSY A;  1YVH A;  3TKZ A;  4M4Z A;  4K11 A;  2EO6 A;  2LNX A;  1BF5 A;  4FL2 A;  2AUG A;  1Y1U A;  4GL9 E;  1BM2 A;  1A08 A;  3VRN A;  2EYY A;  1O4B A;  2HMH A;  2OZO A;  1O4G A;  1A07 A;  3ZNI A;  1KA7 A;  1BHH A;  3US4 A;  2PNB A;  2ETZ A;  1CSZ A;  4OHH A;  2AOB A;  2ECD A;  3S8O A;  1O4A A;  1SPS A;  3BUN B;  1FMK A;  4WWQ A;  1O4D A;  1X6C A;  4TZI A;  4A4B A;  2C0I A;  1A81 A;  2EU0 A;  5BO4 A;  1AYA A;  1H9O A;  2PLD A;  3VS5 A;  2MRK A;  1RQQ C;  1AYC A;  2H5K A;  4K45 A;  3VRP A;  1IJR A;  3N7Y A;  1B47 A;  1BMB A;  3IN7 A;  5DC9 A;  2C0O A;  3N8M A;  4NWF A;  1PIC A;  1D4W A;  1LUK A;  1LKL A;  3HCK A;  2Y1M A;  5DF6 A;  1O47 A;  2LNW A;  1NZL A;  3S8L A;  1LUM A;  3VRQ A;  3GXX A;  3VS0 A;  4D8K A;  2GE9 A;  1BLJ A;  2KK6 A;  1CWE A;  1BHF A;  2FCI A;  2H8H A;  2AOA A;  1MW4 A;  5EHR A;  2OQ1 A;  3MAZ A;  1HCT B;  3VS2 A;  1O4R A;  3S9K A;  1A1A A;  1AYB A;  4F5B A;  3VS3 A;  3VS6 A;  3OVE A;  1KC2 A;  2DX0 A;  4U1P A;  3BUM B;  2PTK A;  1QAD A;  3VRO A;  1F2F A;  5IBM A;  3HHM B;  1GRI A;  1BHH B;  1D1Z A;  5AUL A;  2SRC A;  2DVJ A;  2PNA A;  2LQN A;  1O46 A;  3K2T A;  1AD5 A;  3OB1 B;  2EOB A;  1BG1 A;  2HUW A;  2KNO A;  1XA6 A;  1OPK A;  3S8N A;  3OV1 A;  1A1C A;  2C9W A;  1SHD A;  5HKZ A;  1R1S A;  1JYQ A;  1Y57 A;  5HKY A;  2HDX A;  1BFI A;  1TZE E;  2IUH A;  2K7A B;  3UYO A;  1IS0 A;  4GWF A;  2FO0 A;  3PS5 A;  5HKW A;  1O4J A;  5EEQ A;  1P13 A;  4F59 A;  5GJH A;  3CWG A; 
#chains in the Genus database with same CATH homology
 4JEG A;  1CJ1 A;  1FBV A;  3HIZ B;  4H34 A;  2BBU A;  2PLE A;  3VRY A;  2EL8 A;  4LUD A;  4JE4 A;  2DLY A;  1JYU A;  3GXW A;  3BKB A;  4XZ0 A;  2XP1 A;  2YU7 A;  3T04 A;  1UUR A;  1ZFP E;  3VS7 A;  3IMD A;  3IMJ A;  5EHP A;  5EG3 B;  3VS4 A;  2B3O A;  4L1B B;  2RSY A;  4K44 A;  1RJA A;  3C7I A;  2L4K A;  1D4T A;  1FYR A;  1JYR A;  3BUO B;  1LKK A;  5CDW A;  2CBL A;  4FBN A;  4JGH A;  1O43 A;  2CIA A;  3PSJ A;  1O41 A;  1UUS A;  3CXL A;  1O4C A;  1O49 A;  1A1B A;  1O4K A;  1O4H A;  5I6V A;  2IUG A;  3QWY A;  4NWG A;  3EAZ A;  2VIF A;  3QWX X;  3PLF B;  2YSX A;  2MRJ A;  1F1W A;  1O4N A;  2H46 E;  3M7F A;  1SKJ A;  1R1P A;  1GHU A;  1FU6 A;  1QG1 E;  1O4E A;  1AYD A;  1LCK A;  4P9Z A;  4QSY A;  3GQI B;  5EEL A;  1SHB A;  1BLK A;  2DLZ A;  5KAZ A;  1JU5 A;  2ABL A;  4P9V A;  1AB2 A;  1MIL A;  2JYQ A;  5GJI A;  2DM0 A;  1LUN A;  1R1Q A;  1SHA A;  2IUI A;  2K79 B;  3MXC A;  3BUW B;  4LUE A;  4EIH A;  1M27 A;  4OHE A;  3CD3 A;  2HDV A;  1O4F A;  2IZV A;  2Y3A B;  1KA6 A;  3VRR A;  2MK2 A;  1O4Q A;  1FHS A;  1M61 A;  3PJP A;  1SPR A;  4OHI A;  1AOU F;  1A1E A;  3VRZ A;  1O42 A;  4X6S A;  1A09 A;  1OO4 A;  3EAC A;  2HCK A;  5DC0 B;  1O4M A;  2EO3 A;  1WQU A;  3VGO A;  2DCR A;  2MC1 A;  2LQW A;  1O4P A;  2L6K A;  5IBS A;  2LCT A;  1QCF A;  1RPY A;  1LCJ A;  3N84 A;  2RVF A;  1NZV A;  3PQZ A;  2Y1N A;  4OHD A;  1HCS B;  3VS1 A;  1O44 A;  4F5A A;  2CI9 A;  2EYZ A;  1O4L A;  2SHP A;  5D0J A;  1I3Z A;  1X0N A;  3KFJ A;  2EKX A;  3IN8 A;  5DC4 A;  2EYV A;  3NHN A;  1K9A A;  3UF4 A;  2GSB A;  5AXI A;  4E93 A;  3TL0 A;  4ROJ A;  2CI8 A;  2CS0 A;  2ROR A;  1O48 A;  4EY0 A;  4GPL B;  1AOT F;  2L3T A;  3CBL A;  1G83 A;  1FU5 A;  1LUI A;  1CWD L;  2CRH A;  4A4C A;  4H1O A;  1FBZ A;  4E68 A;  2C0T A;  3K2M A;  3WA4 A;  3MXY A;  3PFV A;  1OPL A;  4FL3 A;  1KSW A;  1TCE A;  1OO3 A;  1O45 A;  1JWO A;  3OB2 B;  4DGP A;  3BUX B;  4OHL A;  2CR4 A;  4XZ1 A;  1BFJ A;  5J3X A;  1BKM A;  1O4I A;  4K2R A;  1Z3K A;  2RMX A;  1NRV A;  2QMS A;  4DGX A;  1X27 A;  1YVL A;  3OP0 A;  3PSK A;  4U17 A;  2MQI A;  1BKL A;  1O4O A;  1CSY A;  1YVH A;  3TKZ A;  4M4Z A;  4K11 A;  2EO6 A;  2LNX A;  1BF5 A;  4FL2 A;  2AUG A;  1Y1U A;  4GL9 E;  1BM2 A;  1A08 A;  3VRN A;  2EYY A;  1O4B A;  2HMH A;  2OZO A;  1O4G A;  1A07 A;  3ZNI A;  1KA7 A;  1BHH A;  3US4 A;  2PNB A;  2ETZ A;  1CSZ A;  4OHH A;  2AOB A;  2ECD A;  3S8O A;  1O4A A;  1SPS A;  3BUN B;  1FMK A;  4WWQ A;  1O4D A;  1X6C A;  4TZI A;  4A4B A;  2C0I A;  1A81 A;  2EU0 A;  5BO4 A;  1AYA A;  1H9O A;  2PLD A;  3VS5 A;  2MRK A;  1RQQ C;  1AYC A;  2H5K A;  4K45 A;  3VRP A;  1IJR A;  3N7Y A;  1B47 A;  1BMB A;  3IN7 A;  5DC9 A;  2C0O A;  3N8M A;  4NWF A;  1PIC A;  1D4W A;  1LUK A;  1LKL A;  3HCK A;  2Y1M A;  5DF6 A;  1O47 A;  2LNW A;  1NZL A;  3S8L A;  1LUM A;  3VRQ A;  3GXX A;  3VS0 A;  4D8K A;  2GE9 A;  1BLJ A;  2KK6 A;  1CWE A;  1BHF A;  2FCI A;  2H8H A;  2AOA A;  1MW4 A;  5EHR A;  2OQ1 A;  3MAZ A;  1HCT B;  3VS2 A;  1O4R A;  3S9K A;  1A1A A;  1AYB A;  4F5B A;  3VS3 A;  3VS6 A;  3OVE A;  1KC2 A;  2DX0 A;  4U1P A;  3BUM B;  2PTK A;  1QAD A;  3VRO A;  1F2F A;  5IBM A;  3HHM B;  1GRI A;  1BHH B;  1D1Z A;  5AUL A;  2SRC A;  2DVJ A;  2PNA A;  2LQN A;  1O46 A;  1AD5 A;  3OB1 B;  2EOB A;  1BG1 A;  2HUW A;  2KNO A;  1XA6 A;  1OPK A;  3S8N A;  3OV1 A;  1A1C A;  2C9W A;  1SHD A;  5HKZ A;  1R1S A;  1JYQ A;  1Y57 A;  5HKY A;  2HDX A;  1BFI A;  1TZE E;  2IUH A;  2K7A B;  3UYO A;  1IS0 A;  4GWF A;  2FO0 A;  3PS5 A;  5HKW A;  1O4J A;  5EEQ A;  1P13 A;  4F59 A;  5GJH A;  3CWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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