1O4LA

Crystal structure of sh2 in complex with fragment2.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4lA00
2OZOA 1LUIA 4K11A 4F5AA 1O4GA 3TL0A 1O48A 1GHUA 4DGXA 1TCEA 1LUMA 1O4CA 3IMDA 3S8NA 2IZVA 1R1PA 3VRRA 4A4BA 1KA6A 1UURA 1FYRA 4P9VA 2LNXA 2K79B 3NHNA 1A07A 5HKYA 2HUWA 1UUSA 1BFJA 5DC0B 2AUGA 4FL2A 4JGHA 1FMKA 4OHEA 2CBLA 1BKLA 2MK2A 2DX0A 1BF5A 4ROJA 1NZVA 3C7IA 1LUNA 3BUNB 3US4A 1O4OA 3OB1B 5EHRA 1BKMA 1O4DA 5I6VA 2FO0A 3GXWA 4JE4A 2IUGA 1H9OA 3HCKA 1FBVA 3VRQA 3MAZA 1O4MA 1O4QA 3QWXX 1ZFPE 1BG1A 1D4TA 2CS0A 1AYBA 1LCJA 3VS3A 3CBLA 4XZ1A 2H5KA 1TZEE 5AXIA 2C0IA 3BUMB 1JU5A 2CI8A 1JYQA 4F59A 4L1BB 3VRZA 2EYZA 1FBZA 3BUWB 1FU6A 1A1AA 1Z3KA 1O4PA 3CD3A 2EL8A 4D8KA 1M61A 1JWOA 1CWEA 1BLKA 1RPYA 2DCRA 1IS0A 3M7FA 4OHLA 1O47A 3VS2A 3VRYA 5GJIA 1PICA 1OPKA 2RVFA 1BMBA 2SRCA 3KFJA 4QSYA 3IMJA 1AYCA 3TKZA 2DLZA 2YSXA 1SPRA 1X6CA 3MXCA 4P9ZA 5KAZA 3VGOA 1GRIA 1CJ1A 1X27A 3UF4A 2MRKA 4X6SA 3VRPA 1O44A 2EKXA 1O4JA 2IUHA 4E68A 1M27A 3BUXB 1LKLA 2DLYA 2H8HA 2C0OA 3OB2B 3CXLA 3VS4A 3QWYA 3IN7A 3N7YA 3WA4A 5IBMA 2ECDA 1AYAA 1WQUA 4K45A 2H46E 4EY0A 4LUEA 4H34A 1YVHA 4OHHA 1BFIA 1K9AA 3S8LA 2CR4A 3HHMB 1NRVA 3UYOA 2MQIA 4A4CA 2DVJA 5EHPA 2YU7A 1BHHB 2Y3AB 1A81A 3BUOB 4LUDA 2OQ1A 1O4BA 2CI9A 3VS7A 1A1CA 1LKKA 1QCFA 3PQZA 2XP1A 1A08A 4U1PA 2EYVA 1MILA 1R1QA 1YVLA 3EACA 2MC1A 2PTKA 2KK6A 1MW4A 1O4AA 1O4HA 1IJRA 3K2MA 2RORA 2PLEA 2HDXA 3VS6A 1AOUF 3T04A 2L6KA 2PNBA 1A1BA 2HMHA 4H1OA 1O49A 2RMXA 1KA7A 4TZIA 1A1EA 1F2FA 1SHBA 2Y1MA 5DC4A 3OV1A 2SHPA 3PSKA 4DGPA 1Y1UA 5EG3B 1O4RA 1O46A 2CRHA 1AD5A 1SPSA 2ABLA 2MRJA 1HCSB 1FHSA 1O4FA 1BHHA 1OO3A 4NWFA 1P13A 4EIHA 2EO3A 1CSYA 3N84A 1OPLA 1OO4A 4GPLB 1O4IA 5GJHA 2ETZA 2EYYA 4F5BA 2L4KA 1Y57A 4XZ0A 2BBUA 2CIAA 2JYQA 3N8MA 2DM0A 1JYUA 2Y1NA 1D1ZA 2HDVA 2LQNA 1SKJA 3BKBA 3PS5A 1CWDL 1B47A 5BO4A 3CWGA 1KC2A 3VS1A 3VS5A 3VROA 5HKZA 1JYRA 2FCIA 1KSWA 5AULA 4K44A 1AB2A 5IBSA 1R1SA 5EEQA 2LQWA 1O45A 1QG1E 1O43A 2C0TA 1O4LA 1BM2A 1SHAA 5HKWA 1LCKA 1FU5A 2AOAA 3S9KA 2AOBA 4JEGA 1O41A 4E93A 3VRNA 1O4KA 4FL3A 2QMSA 2KNOA 2PNAA 1SHDA 2C9WA 3GXXA 2EO6A 1AOTF 1F1WA 3VS0A 1AYDA 2PLDA 1XA6A 2EOBA 5J3XA 3OVEA 1RQQC 1G83A 1NZLA 1LUKA 1O42A 2HCKA 2B3OA 4OHIA 1CSZA 2GE9A 2LCTA 3GQIB 5DC9A 2LNWA 1RJAA 1QADA 1I3ZA 2L3TA 1O4NA 4GL9E 5D0JA 5DF6A 2EU0A 4FBNA 3PJPA 2K7AB 3S8OA 1X0NA 1D4WA 4M4ZA 1BHFA 1HCTB 4GWFA 3PLFB 2VIFA 4OHDA 1O4EA 1A09A 4U17A 3ZNIA 3MXYA 3OP0A 4K2RA 5CDWA 4WWQA 2RSYA 5EELA 2GSBA 2IUIA 1BLJA 4NWGA 3PSJA 3IN8A 3EAZA 3HIZB 3PFVA
chains in the Genus database with same CATH superfamily
2OZOA 1LUIA 4K11A 4F5AA 1O4GA 3TL0A 1O48A 1GHUA 4DGXA 1TCEA 1LUMA 1O4CA 3IMDA 3S8NA 2IZVA 1R1PA 3VRRA 4A4BA 1KA6A 1UURA 1FYRA 4P9VA 2LNXA 2K79B 3NHNA 1A07A 5HKYA 2HUWA 1UUSA 1BFJA 5DC0B 2AUGA 4FL2A 4JGHA 1FMKA 4OHEA 2CBLA 1BKLA 2MK2A 2DX0A 1BF5A 4ROJA 1NZVA 3C7IA 1LUNA 3BUNB 3US4A 1O4OA 3OB1B 5EHRA 1BKMA 1O4DA 5I6VA 2FO0A 3GXWA 4JE4A 2IUGA 1H9OA 3HCKA 1FBVA 3VRQA 3MAZA 1O4MA 1O4QA 3QWXX 1ZFPE 1BG1A 1D4TA 2CS0A 1AYBA 1LCJA 3VS3A 3CBLA 4XZ1A 2H5KA 1TZEE 5AXIA 2C0IA 3BUMB 1JU5A 2CI8A 1JYQA 4F59A 4L1BB 3VRZA 2EYZA 1FBZA 3BUWB 1FU6A 1A1AA 1Z3KA 1O4PA 3CD3A 2EL8A 4D8KA 1M61A 1JWOA 1CWEA 1BLKA 1RPYA 2DCRA 1IS0A 3M7FA 4OHLA 1O47A 3VS2A 3VRYA 5GJIA 1PICA 1OPKA 2RVFA 1BMBA 2SRCA 3KFJA 4QSYA 3IMJA 1AYCA 3TKZA 3K2TA 2DLZA 2YSXA 1SPRA 1X6CA 3MXCA 4P9ZA 5KAZA 3VGOA 1GRIA 1CJ1A 1X27A 3UF4A 2MRKA 4X6SA 3VRPA 1O44A 2EKXA 1O4JA 2IUHA 4E68A 1M27A 3BUXB 1LKLA 2DLYA 2H8HA 2C0OA 3OB2B 3CXLA 3VS4A 3QWYA 3IN7A 3N7YA 3WA4A 5IBMA 2ECDA 1AYAA 1WQUA 4K45A 2H46E 4EY0A 4LUEA 4H34A 1YVHA 4OHHA 1BFIA 1K9AA 3S8LA 2CR4A 3HHMB 1NRVA 3UYOA 2MQIA 4A4CA 2DVJA 5EHPA 2YU7A 1BHHB 2Y3AB 1A81A 3BUOB 4LUDA 2OQ1A 2KGYA 1O4BA 2CI9A 3VS7A 1A1CA 1LKKA 1QCFA 3PQZA 2XP1A 1A08A 4U1PA 2EYVA 1MILA 1R1QA 1YVLA 3EACA 2MC1A 2PTKA 2KK6A 1MW4A 1O4AA 1O4HA 1IJRA 3K2MA 2RORA 2PLEA 2HDXA 3VS6A 1AOUF 3T04A 2L6KA 2PNBA 1A1BA 2HMHA 4H1OA 1O49A 2RMXA 1KA7A 4TZIA 1A1EA 1F2FA 1SHBA 2Y1MA 5DC4A 3OV1A 2SHPA 3PSKA 4DGPA 1Y1UA 5EG3B 1O4RA 1O46A 2CRHA 1AD5A 1SPSA 2ABLA 2MRJA 1HCSB 1FHSA 1O4FA 1BHHA 1OO3A 4NWFA 1P13A 4EIHA 2EO3A 1CSYA 3N84A 1OPLA 1OO4A 4GPLB 2LRAA 1O4IA 5GJHA 2ETZA 2EYYA 4F5BA 2L4KA 1Y57A 4XZ0A 2BBUA 2CIAA 2JYQA 3N8MA 2DM0A 1JYUA 2Y1NA 1D1ZA 2HDVA 2LQNA 1SKJA 3BKBA 3PS5A 1CWDL 1B47A 5BO4A 3CWGA 1KC2A 3VS1A 3VS5A 3VROA 5HKZA 1JYRA 2FCIA 1KSWA 5AULA 4K44A 1AB2A 5IBSA 1R1SA 5EEQA 2LQWA 1O45A 1QG1E 1O43A 2C0TA 1O4LA 1BM2A 1SHAA 5HKWA 1LCKA 1FU5A 2AOAA 3S9KA 2AOBA 4JEGA 1O41A 4E93A 3LYVA 3VRNA 1O4KA 4FL3A 2QMSA 2KNOA 2PNAA 1SHDA 2C9WA 3GXXA 2EO6A 1AOTF 1F1WA 3VS0A 1AYDA 2PLDA 1XA6A 2EOBA 5J3XA 3OVEA 1RQQC 1G83A 1NZLA 1LUKA 1O42A 2HCKA 2B3OA 4OHIA 1CSZA 2GE9A 2LCTA 3GQIB 5DC9A 2LNWA 1RJAA 1QADA 1I3ZA 2L3TA 1O4NA 4GL9E 5D0JA 5DF6A 2EU0A 4FBNA 3PJPA 2K7AB 3S8OA 1X0NA 1D4WA 4M4ZA 1BHFA 1HCTB 4GWFA 3PLFB 2VIFA 4OHDA 1O4EA 1A09A 4U17A 3ZNIA 3MXYA 3OP0A 4K2RA 5CDWA 4WWQA 2RSYA 5EELA 2GSBA 2IUIA 1BLJA 4NWGA 3PSJA 3IN8A 3EAZA 3HIZB 3PFVA
chains in the Genus database with same CATH topology
2OZOA 1LUIA 4K11A 4F5AA 1O4GA 3TL0A 1O48A 1GHUA 4DGXA 1TCEA 1LUMA 1O4CA 3IMDA 3S8NA 2IZVA 1R1PA 3VRRA 4A4BA 1KA6A 1UURA 1FYRA 4P9VA 2LNXA 2K79B 3NHNA 1A07A 5HKYA 2HUWA 1UUSA 1BFJA 5DC0B 2AUGA 4FL2A 4JGHA 1FMKA 4OHEA 2CBLA 1BKLA 2MK2A 2DX0A 1BF5A 4ROJA 1NZVA 3C7IA 1LUNA 3BUNB 3US4A 1O4OA 3OB1B 5EHRA 1BKMA 1O4DA 5I6VA 2FO0A 3GXWA 4JE4A 2IUGA 1H9OA 3HCKA 1FBVA 3VRQA 3MAZA 1O4MA 1O4QA 3QWXX 1ZFPE 1BG1A 1D4TA 2CS0A 1AYBA 1LCJA 3VS3A 3CBLA 4XZ1A 2H5KA 1TZEE 5AXIA 2C0IA 3BUMB 1JU5A 2CI8A 1JYQA 4F59A 4L1BB 3VRZA 2EYZA 1FBZA 3BUWB 1FU6A 1A1AA 1Z3KA 1O4PA 3CD3A 2EL8A 4D8KA 1M61A 1JWOA 1CWEA 1BLKA 1RPYA 2DCRA 1IS0A 3M7FA 4OHLA 1O47A 3VS2A 3VRYA 5GJIA 1PICA 1OPKA 2RVFA 1BMBA 2SRCA 3KFJA 4QSYA 3IMJA 1AYCA 3TKZA 2DLZA 2YSXA 1SPRA 1X6CA 3MXCA 4P9ZA 5KAZA 3VGOA 1GRIA 1CJ1A 1X27A 3UF4A 2MRKA 4X6SA 3VRPA 1O44A 2EKXA 1O4JA 2IUHA 4E68A 1M27A 3BUXB 1LKLA 2DLYA 2H8HA 2C0OA 3OB2B 3CXLA 3VS4A 3QWYA 3IN7A 3N7YA 3WA4A 5IBMA 2ECDA 1AYAA 1WQUA 4K45A 2H46E 4EY0A 4LUEA 4H34A 1YVHA 4OHHA 1BFIA 1K9AA 3S8LA 2CR4A 3HHMB 1NRVA 3UYOA 2MQIA 4A4CA 2DVJA 5EHPA 2YU7A 1BHHB 2Y3AB 1A81A 3BUOB 4LUDA 2OQ1A 1O4BA 2CI9A 3VS7A 1A1CA 1LKKA 1QCFA 3PQZA 2XP1A 1A08A 4U1PA 2EYVA 1MILA 1R1QA 1YVLA 3EACA 2MC1A 2PTKA 2KK6A 1MW4A 1O4AA 1O4HA 1IJRA 3K2MA 2RORA 2PLEA 2HDXA 3VS6A 1AOUF 3T04A 2L6KA 2PNBA 1A1BA 2HMHA 4H1OA 1O49A 2RMXA 1KA7A 4TZIA 1A1EA 1F2FA 1SHBA 2Y1MA 5DC4A 3OV1A 2SHPA 3PSKA 4DGPA 1Y1UA 5EG3B 1O4RA 1O46A 2CRHA 1AD5A 1SPSA 2ABLA 2MRJA 1HCSB 1FHSA 1O4FA 1BHHA 1OO3A 4NWFA 1P13A 4EIHA 2EO3A 1CSYA 3N84A 1OPLA 1OO4A 4GPLB 1O4IA 5GJHA 2ETZA 2EYYA 4F5BA 2L4KA 1Y57A 4XZ0A 2BBUA 2CIAA 2JYQA 3N8MA 2DM0A 1JYUA 2Y1NA 1D1ZA 2HDVA 2LQNA 1SKJA 3BKBA 3PS5A 1CWDL 1B47A 5BO4A 3CWGA 1KC2A 3VS1A 3VS5A 3VROA 5HKZA 1JYRA 2FCIA 1KSWA 5AULA 4K44A 1AB2A 5IBSA 1R1SA 5EEQA 2LQWA 1O45A 1QG1E 1O43A 2C0TA 1O4LA 1BM2A 1SHAA 5HKWA 1LCKA 1FU5A 2AOAA 3S9KA 2AOBA 4JEGA 1O41A 4E93A 3VRNA 1O4KA 4FL3A 2QMSA 2KNOA 2PNAA 1SHDA 2C9WA 3GXXA 2EO6A 1AOTF 1F1WA 3VS0A 1AYDA 2PLDA 1XA6A 2EOBA 5J3XA 3OVEA 1RQQC 1G83A 1NZLA 1LUKA 1O42A 2HCKA 2B3OA 4OHIA 1CSZA 2GE9A 2LCTA 3GQIB 5DC9A 2LNWA 1RJAA 1QADA 1I3ZA 2L3TA 1O4NA 4GL9E 5D0JA 5DF6A 2EU0A 4FBNA 3PJPA 2K7AB 3S8OA 1X0NA 1D4WA 4M4ZA 1BHFA 1HCTB 4GWFA 3PLFB 2VIFA 4OHDA 1O4EA 1A09A 4U17A 3ZNIA 3MXYA 3OP0A 4K2RA 5CDWA 4WWQA 2RSYA 5EELA 2GSBA 2IUIA 1BLJA 4NWGA 3PSJA 3IN8A 3EAZA 3HIZB 3PFVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OZO A;  1LUI A;  4K11 A;  4F5A A;  1O4G A;  3TL0 A;  1O48 A;  1GHU A;  4DGX A;  1TCE A;  1LUM A;  1O4C A;  3IMD A;  3S8N A;  2IZV A;  1R1P A;  3VRR A;  4A4B A;  1KA6 A;  1UUR A;  1FYR A;  4P9V A;  2LNX A;  2K79 B;  3NHN A;  1A07 A;  5HKY A;  2HUW A;  1UUS A;  1BFJ A;  5DC0 B;  2AUG A;  4FL2 A;  4JGH A;  1FMK A;  4OHE A;  2CBL A;  1BKL A;  2MK2 A;  2DX0 A;  1BF5 A;  4ROJ A;  1NZV A;  3C7I A;  1LUN A;  3BUN B;  3US4 A;  1O4O A;  3OB1 B;  5EHR A;  1BKM A;  1O4D A;  5I6V A;  2FO0 A;  3GXW A;  4JE4 A;  2IUG A;  1H9O A;  3HCK A;  1FBV A;  3VRQ A;  3MAZ A;  1O4M A;  1O4Q A;  3QWX X;  1ZFP E;  1BG1 A;  1D4T A;  2CS0 A;  1AYB A;  1LCJ A;  3VS3 A;  3CBL A;  4XZ1 A;  2H5K A;  1TZE E;  5AXI A;  2C0I A;  3BUM B;  1JU5 A;  2CI8 A;  1JYQ A;  4F59 A;  4L1B B;  3VRZ A;  2EYZ A;  1FBZ A;  3BUW B;  1FU6 A;  1A1A A;  1Z3K A;  1O4P A;  3CD3 A;  2EL8 A;  4D8K A;  1M61 A;  1JWO A;  1CWE A;  1BLK A;  1RPY A;  2DCR A;  1IS0 A;  3M7F A;  4OHL A;  1O47 A;  3VS2 A;  3VRY A;  5GJI A;  1PIC A;  1OPK A;  2RVF A;  1BMB A;  2SRC A;  3KFJ A;  4QSY A;  3IMJ A;  1AYC A;  3TKZ A;  2DLZ A;  2YSX A;  1SPR A;  1X6C A;  3MXC A;  4P9Z A;  5KAZ A;  3VGO A;  1GRI A;  1CJ1 A;  1X27 A;  3UF4 A;  2MRK A;  4X6S A;  3VRP A;  1O44 A;  2EKX A;  1O4J A;  2IUH A;  4E68 A;  1M27 A;  3BUX B;  1LKL A;  2DLY A;  2H8H A;  2C0O A;  3OB2 B;  3CXL A;  3VS4 A;  3QWY A;  3IN7 A;  3N7Y A;  3WA4 A;  5IBM A;  2ECD A;  1AYA A;  1WQU A;  4K45 A;  2H46 E;  4EY0 A;  4LUE A;  4H34 A;  1YVH A;  4OHH A;  1BFI A;  1K9A A;  3S8L A;  2CR4 A;  3HHM B;  1NRV A;  3UYO A;  2MQI A;  4A4C A;  2DVJ A;  5EHP A;  2YU7 A;  1BHH B;  2Y3A B;  1A81 A;  3BUO B;  4LUD A;  2OQ1 A;  1O4B A;  2CI9 A;  3VS7 A;  1A1C A;  1LKK A;  1QCF A;  3PQZ A;  2XP1 A;  1A08 A;  4U1P A;  2EYV A;  1MIL A;  1R1Q A;  1YVL A;  3EAC A;  2MC1 A;  2PTK A;  2KK6 A;  1MW4 A;  1O4A A;  1O4H A;  1IJR A;  3K2M A;  2ROR A;  2PLE A;  2HDX A;  3VS6 A;  1AOU F;  3T04 A;  2L6K A;  2PNB A;  1A1B A;  2HMH A;  4H1O A;  1O49 A;  2RMX A;  1KA7 A;  4TZI A;  1A1E A;  1F2F A;  1SHB A;  2Y1M A;  5DC4 A;  3OV1 A;  2SHP A;  3PSK A;  4DGP A;  1Y1U A;  5EG3 B;  1O4R A;  1O46 A;  2CRH A;  1AD5 A;  1SPS A;  2ABL A;  2MRJ A;  1HCS B;  1FHS A;  1O4F A;  1BHH A;  1OO3 A;  4NWF A;  1P13 A;  4EIH A;  2EO3 A;  1CSY A;  3N84 A;  1OPL A;  1OO4 A;  4GPL B;  1O4I A;  5GJH A;  2ETZ A;  2EYY A;  4F5B A;  2L4K A;  1Y57 A;  4XZ0 A;  2BBU A;  2CIA A;  2JYQ A;  3N8M A;  2DM0 A;  1JYU A;  2Y1N A;  1D1Z A;  2HDV A;  2LQN A;  1SKJ A;  3BKB A;  3PS5 A;  1CWD L;  1B47 A;  5BO4 A;  3CWG A;  1KC2 A;  3VS1 A;  3VS5 A;  3VRO A;  5HKZ A;  1JYR A;  2FCI A;  1KSW A;  5AUL A;  4K44 A;  1AB2 A;  5IBS A;  1R1S A;  5EEQ A;  2LQW A;  1O45 A;  1QG1 E;  1O43 A;  2C0T A;  1O4L A;  1BM2 A;  1SHA A;  5HKW A;  1LCK A;  1FU5 A;  2AOA A;  3S9K A;  2AOB A;  4JEG A;  1O41 A;  4E93 A;  3VRN A;  1O4K A;  4FL3 A;  2QMS A;  2KNO A;  2PNA A;  1SHD A;  2C9W A;  3GXX A;  2EO6 A;  1AOT F;  1F1W A;  3VS0 A;  1AYD A;  2PLD A;  1XA6 A;  2EOB A;  5J3X A;  3OVE A;  1RQQ C;  1G83 A;  1NZL A;  1LUK A;  1O42 A;  2HCK A;  2B3O A;  4OHI A;  1CSZ A;  2GE9 A;  2LCT A;  3GQI B;  5DC9 A;  2LNW A;  1RJA A;  1QAD A;  1I3Z A;  2L3T A;  1O4N A;  4GL9 E;  5D0J A;  5DF6 A;  2EU0 A;  4FBN A;  3PJP A;  2K7A B;  3S8O A;  1X0N A;  1D4W A;  4M4Z A;  1BHF A;  1HCT B;  4GWF A;  3PLF B;  2VIF A;  4OHD A;  1O4E A;  1A09 A;  4U17 A;  3ZNI A;  3MXY A;  3OP0 A;  4K2R A;  5CDW A;  4WWQ A;  2RSY A;  5EEL A;  2GSB A;  2IUI A;  1BLJ A;  4NWG A;  3PSJ A;  3IN8 A;  3EAZ A;  3HIZ B;  3PFV A; 
#chains in the Genus database with same CATH topology
 2OZO A;  1LUI A;  4K11 A;  4F5A A;  1O4G A;  3TL0 A;  1O48 A;  1GHU A;  4DGX A;  1TCE A;  1LUM A;  1O4C A;  3IMD A;  3S8N A;  2IZV A;  1R1P A;  3VRR A;  4A4B A;  1KA6 A;  1UUR A;  1FYR A;  4P9V A;  2LNX A;  2K79 B;  3NHN A;  1A07 A;  5HKY A;  2HUW A;  1UUS A;  1BFJ A;  5DC0 B;  2AUG A;  4FL2 A;  4JGH A;  1FMK A;  4OHE A;  2CBL A;  1BKL A;  2MK2 A;  2DX0 A;  1BF5 A;  4ROJ A;  1NZV A;  3C7I A;  1LUN A;  3BUN B;  3US4 A;  1O4O A;  3OB1 B;  5EHR A;  1BKM A;  1O4D A;  5I6V A;  2FO0 A;  3GXW A;  4JE4 A;  2IUG A;  1H9O A;  3HCK A;  1FBV A;  3VRQ A;  3MAZ A;  1O4M A;  1O4Q A;  3QWX X;  1ZFP E;  1BG1 A;  1D4T A;  2CS0 A;  1AYB A;  1LCJ A;  3VS3 A;  3CBL A;  4XZ1 A;  2H5K A;  1TZE E;  5AXI A;  2C0I A;  3BUM B;  1JU5 A;  2CI8 A;  1JYQ A;  4F59 A;  4L1B B;  3VRZ A;  2EYZ A;  1FBZ A;  3BUW B;  1FU6 A;  1A1A A;  1Z3K A;  1O4P A;  3CD3 A;  2EL8 A;  4D8K A;  1M61 A;  1JWO A;  1CWE A;  1BLK A;  1RPY A;  2DCR A;  1IS0 A;  3M7F A;  4OHL A;  1O47 A;  3VS2 A;  3VRY A;  5GJI A;  1PIC A;  1OPK A;  2RVF A;  1BMB A;  2SRC A;  3KFJ A;  4QSY A;  3IMJ A;  1AYC A;  3TKZ A;  3K2T A;  2DLZ A;  2YSX A;  1SPR A;  1X6C A;  3MXC A;  4P9Z A;  5KAZ A;  3VGO A;  1GRI A;  1CJ1 A;  1X27 A;  3UF4 A;  2MRK A;  4X6S A;  3VRP A;  1O44 A;  2EKX A;  1O4J A;  2IUH A;  4E68 A;  1M27 A;  3BUX B;  1LKL A;  2DLY A;  2H8H A;  2C0O A;  3OB2 B;  3CXL A;  3VS4 A;  3QWY A;  3IN7 A;  3N7Y A;  3WA4 A;  5IBM A;  2ECD A;  1AYA A;  1WQU A;  4K45 A;  2H46 E;  4EY0 A;  4LUE A;  4H34 A;  1YVH A;  4OHH A;  1BFI A;  1K9A A;  3S8L A;  2CR4 A;  3HHM B;  1NRV A;  3UYO A;  2MQI A;  4A4C A;  2DVJ A;  5EHP A;  2YU7 A;  1BHH B;  2Y3A B;  1A81 A;  3BUO B;  4LUD A;  2OQ1 A;  2KGY A;  1O4B A;  2CI9 A;  3VS7 A;  1A1C A;  1LKK A;  1QCF A;  3PQZ A;  2XP1 A;  1A08 A;  4U1P A;  2EYV A;  1MIL A;  1R1Q A;  1YVL A;  3EAC A;  2MC1 A;  2PTK A;  2KK6 A;  1MW4 A;  1O4A A;  1O4H A;  1IJR A;  3K2M A;  2ROR A;  2PLE A;  2HDX A;  3VS6 A;  1AOU F;  3T04 A;  2L6K A;  2PNB A;  1A1B A;  2HMH A;  4H1O A;  1O49 A;  2RMX A;  1KA7 A;  4TZI A;  1A1E A;  1F2F A;  1SHB A;  2Y1M A;  5DC4 A;  3OV1 A;  2SHP A;  3PSK A;  4DGP A;  1Y1U A;  5EG3 B;  1O4R A;  1O46 A;  2CRH A;  1AD5 A;  1SPS A;  2ABL A;  2MRJ A;  1HCS B;  1FHS A;  1O4F A;  1BHH A;  1OO3 A;  4NWF A;  1P13 A;  4EIH A;  2EO3 A;  1CSY A;  3N84 A;  1OPL A;  1OO4 A;  4GPL B;  2LRA A;  1O4I A;  5GJH A;  2ETZ A;  2EYY A;  4F5B A;  2L4K A;  1Y57 A;  4XZ0 A;  2BBU A;  2CIA A;  2JYQ A;  3N8M A;  2DM0 A;  1JYU A;  2Y1N A;  1D1Z A;  2HDV A;  2LQN A;  1SKJ A;  3BKB A;  3PS5 A;  1CWD L;  1B47 A;  5BO4 A;  3CWG A;  1KC2 A;  3VS1 A;  3VS5 A;  3VRO A;  5HKZ A;  1JYR A;  2FCI A;  1KSW A;  5AUL A;  4K44 A;  1AB2 A;  5IBS A;  1R1S A;  5EEQ A;  2LQW A;  1O45 A;  1QG1 E;  1O43 A;  2C0T A;  1O4L A;  1BM2 A;  1SHA A;  5HKW A;  1LCK A;  1FU5 A;  2AOA A;  3S9K A;  2AOB A;  4JEG A;  1O41 A;  4E93 A;  3LYV A;  3VRN A;  1O4K A;  4FL3 A;  2QMS A;  2KNO A;  2PNA A;  1SHD A;  2C9W A;  3GXX A;  2EO6 A;  1AOT F;  1F1W A;  3VS0 A;  1AYD A;  2PLD A;  1XA6 A;  2EOB A;  5J3X A;  3OVE A;  1RQQ C;  1G83 A;  1NZL A;  1LUK A;  1O42 A;  2HCK A;  2B3O A;  4OHI A;  1CSZ A;  2GE9 A;  2LCT A;  3GQI B;  5DC9 A;  2LNW A;  1RJA A;  1QAD A;  1I3Z A;  2L3T A;  1O4N A;  4GL9 E;  5D0J A;  5DF6 A;  2EU0 A;  4FBN A;  3PJP A;  2K7A B;  3S8O A;  1X0N A;  1D4W A;  4M4Z A;  1BHF A;  1HCT B;  4GWF A;  3PLF B;  2VIF A;  4OHD A;  1O4E A;  1A09 A;  4U17 A;  3ZNI A;  3MXY A;  3OP0 A;  4K2R A;  5CDW A;  4WWQ A;  2RSY A;  5EEL A;  2GSB A;  2IUI A;  1BLJ A;  4NWG A;  3PSJ A;  3IN8 A;  3EAZ A;  3HIZ B;  3PFV A; 
#chains in the Genus database with same CATH homology
 2OZO A;  1LUI A;  4K11 A;  4F5A A;  1O4G A;  3TL0 A;  1O48 A;  1GHU A;  4DGX A;  1TCE A;  1LUM A;  1O4C A;  3IMD A;  3S8N A;  2IZV A;  1R1P A;  3VRR A;  4A4B A;  1KA6 A;  1UUR A;  1FYR A;  4P9V A;  2LNX A;  2K79 B;  3NHN A;  1A07 A;  5HKY A;  2HUW A;  1UUS A;  1BFJ A;  5DC0 B;  2AUG A;  4FL2 A;  4JGH A;  1FMK A;  4OHE A;  2CBL A;  1BKL A;  2MK2 A;  2DX0 A;  1BF5 A;  4ROJ A;  1NZV A;  3C7I A;  1LUN A;  3BUN B;  3US4 A;  1O4O A;  3OB1 B;  5EHR A;  1BKM A;  1O4D A;  5I6V A;  2FO0 A;  3GXW A;  4JE4 A;  2IUG A;  1H9O A;  3HCK A;  1FBV A;  3VRQ A;  3MAZ A;  1O4M A;  1O4Q A;  3QWX X;  1ZFP E;  1BG1 A;  1D4T A;  2CS0 A;  1AYB A;  1LCJ A;  3VS3 A;  3CBL A;  4XZ1 A;  2H5K A;  1TZE E;  5AXI A;  2C0I A;  3BUM B;  1JU5 A;  2CI8 A;  1JYQ A;  4F59 A;  4L1B B;  3VRZ A;  2EYZ A;  1FBZ A;  3BUW B;  1FU6 A;  1A1A A;  1Z3K A;  1O4P A;  3CD3 A;  2EL8 A;  4D8K A;  1M61 A;  1JWO A;  1CWE A;  1BLK A;  1RPY A;  2DCR A;  1IS0 A;  3M7F A;  4OHL A;  1O47 A;  3VS2 A;  3VRY A;  5GJI A;  1PIC A;  1OPK A;  2RVF A;  1BMB A;  2SRC A;  3KFJ A;  4QSY A;  3IMJ A;  1AYC A;  3TKZ A;  2DLZ A;  2YSX A;  1SPR A;  1X6C A;  3MXC A;  4P9Z A;  5KAZ A;  3VGO A;  1GRI A;  1CJ1 A;  1X27 A;  3UF4 A;  2MRK A;  4X6S A;  3VRP A;  1O44 A;  2EKX A;  1O4J A;  2IUH A;  4E68 A;  1M27 A;  3BUX B;  1LKL A;  2DLY A;  2H8H A;  2C0O A;  3OB2 B;  3CXL A;  3VS4 A;  3QWY A;  3IN7 A;  3N7Y A;  3WA4 A;  5IBM A;  2ECD A;  1AYA A;  1WQU A;  4K45 A;  2H46 E;  4EY0 A;  4LUE A;  4H34 A;  1YVH A;  4OHH A;  1BFI A;  1K9A A;  3S8L A;  2CR4 A;  3HHM B;  1NRV A;  3UYO A;  2MQI A;  4A4C A;  2DVJ A;  5EHP A;  2YU7 A;  1BHH B;  2Y3A B;  1A81 A;  3BUO B;  4LUD A;  2OQ1 A;  1O4B A;  2CI9 A;  3VS7 A;  1A1C A;  1LKK A;  1QCF A;  3PQZ A;  2XP1 A;  1A08 A;  4U1P A;  2EYV A;  1MIL A;  1R1Q A;  1YVL A;  3EAC A;  2MC1 A;  2PTK A;  2KK6 A;  1MW4 A;  1O4A A;  1O4H A;  1IJR A;  3K2M A;  2ROR A;  2PLE A;  2HDX A;  3VS6 A;  1AOU F;  3T04 A;  2L6K A;  2PNB A;  1A1B A;  2HMH A;  4H1O A;  1O49 A;  2RMX A;  1KA7 A;  4TZI A;  1A1E A;  1F2F A;  1SHB A;  2Y1M A;  5DC4 A;  3OV1 A;  2SHP A;  3PSK A;  4DGP A;  1Y1U A;  5EG3 B;  1O4R A;  1O46 A;  2CRH A;  1AD5 A;  1SPS A;  2ABL A;  2MRJ A;  1HCS B;  1FHS A;  1O4F A;  1BHH A;  1OO3 A;  4NWF A;  1P13 A;  4EIH A;  2EO3 A;  1CSY A;  3N84 A;  1OPL A;  1OO4 A;  4GPL B;  1O4I A;  5GJH A;  2ETZ A;  2EYY A;  4F5B A;  2L4K A;  1Y57 A;  4XZ0 A;  2BBU A;  2CIA A;  2JYQ A;  3N8M A;  2DM0 A;  1JYU A;  2Y1N A;  1D1Z A;  2HDV A;  2LQN A;  1SKJ A;  3BKB A;  3PS5 A;  1CWD L;  1B47 A;  5BO4 A;  3CWG A;  1KC2 A;  3VS1 A;  3VS5 A;  3VRO A;  5HKZ A;  1JYR A;  2FCI A;  1KSW A;  5AUL A;  4K44 A;  1AB2 A;  5IBS A;  1R1S A;  5EEQ A;  2LQW A;  1O45 A;  1QG1 E;  1O43 A;  2C0T A;  1O4L A;  1BM2 A;  1SHA A;  5HKW A;  1LCK A;  1FU5 A;  2AOA A;  3S9K A;  2AOB A;  4JEG A;  1O41 A;  4E93 A;  3VRN A;  1O4K A;  4FL3 A;  2QMS A;  2KNO A;  2PNA A;  1SHD A;  2C9W A;  3GXX A;  2EO6 A;  1AOT F;  1F1W A;  3VS0 A;  1AYD A;  2PLD A;  1XA6 A;  2EOB A;  5J3X A;  3OVE A;  1RQQ C;  1G83 A;  1NZL A;  1LUK A;  1O42 A;  2HCK A;  2B3O A;  4OHI A;  1CSZ A;  2GE9 A;  2LCT A;  3GQI B;  5DC9 A;  2LNW A;  1RJA A;  1QAD A;  1I3Z A;  2L3T A;  1O4N A;  4GL9 E;  5D0J A;  5DF6 A;  2EU0 A;  4FBN A;  3PJP A;  2K7A B;  3S8O A;  1X0N A;  1D4W A;  4M4Z A;  1BHF A;  1HCT B;  4GWF A;  3PLF B;  2VIF A;  4OHD A;  1O4E A;  1A09 A;  4U17 A;  3ZNI A;  3MXY A;  3OP0 A;  4K2R A;  5CDW A;  4WWQ A;  2RSY A;  5EEL A;  2GSB A;  2IUI A;  1BLJ A;  4NWG A;  3PSJ A;  3IN8 A;  3EAZ A;  3HIZ B;  3PFV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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