1O4MA

Crystal structure of sh2 in complex with malonicacid.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 27
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4mA00
3UF4A 1BM2A 3N7YA 2MQIA 1BG1A 1O4RA 1O4FA 1KC2A 2AOBA 2FCIA 1FBZA 1MW4A 2H5KA 1O4NA 1QCFA 1O4MA 1WQUA 2CI8A 1Y1UA 1M27A 2VIFA 5GJHA 3MAZA 2FO0A 5DF6A 2CR4A 1FYRA 2KNOA 1O4IA 1BHHB 4FL2A 1IS0A 2HMHA 4L1BB 1NZVA 3CBLA 5EG3B 3VROA 1A1BA 5EEQA 3VRPA 1SHAA 2IZVA 2IUGA 1XA6A 1BKMA 1A1EA 4K2RA 2EO3A 5GJIA 1O4KA 2EU0A 3IMDA 4E68A 1AB2A 1YVLA 3OVEA 3S9KA 1CSZA 1O4LA 1F1WA 1AYDA 3N84A 5D0JA 2HDVA 2RSYA 1SHBA 1KA7A 4GL9E 3IN7A 3OP0A 3BUWB 4OHLA 2EYYA 3HIZB 3BUXB 4F5BA 2EYZA 1A81A 1RQQC 1O46A 1HCSB 1O47A 5EELA 1A07A 1Y57A 5KAZA 4ROJA 2LNWA 1O4QA 3OV1A 1O4DA 3VGOA 2GE9A 4K45A 1BMBA 2MC1A 1R1QA 1O4GA 1LCKA 2PLEA 1BHFA 1JYRA 1KSWA 1P13A 3PSKA 1FU5A 3BUNB 2C0OA 1O4AA 3EAZA 5J3XA 2EYVA 4U17A 1CWEA 1O4HA 3EACA 1RPYA 2IUHA 3PLFB 3PSJA 3NHNA 4EIHA 1SKJA 2H8HA 1X0NA 3MXYA 3IN8A 1BKLA 1FU6A 1JWOA 4OHDA 1OO4A 2ETZA 1NRVA 1UURA 4TZIA 2OZOA 1PICA 1GHUA 2ABLA 4H1OA 2HDXA 1K9AA 1LUKA 4JE4A 3TKZA 4NWGA 1AYAA 1O4JA 4EY0A 1CJ1A 2AUGA 2CI9A 3GXXA 4U1PA 3VS5A 4A4CA 1O4CA 4OHEA 2RVFA 2C0IA 4GWFA 1BLKA 1O49A 1FMKA 1SPRA 3KFJA 2RORA 3VS0A 2L6KA 2PNAA 3IMJA 2LQWA 2K7AB 4GPLB 3MXCA 3M7FA 2SRCA 2CBLA 3VRNA 1O43A 1CSYA 4DGPA 2Y1MA 2LCTA 4QSYA 2GSBA 1LUNA 1AYBA 1LKLA 3BUOB 2PTKA 3VRQA 3CXLA 4P9VA 1O42A 4E93A 1F2FA 4NWFA 1G83A 1R1PA 3WA4A 4P9ZA 1O48A 3PS5A 3S8NA 5IBMA 1AOTF 3T04A 2K79B 1TCEA 3VS1A 2IUIA 3VS2A 1JYQA 1KA6A 1JYUA 4K11A 3VS6A 2EKXA 2MRJA 2LQNA 5CDWA 2KK6A 5DC0B 1O45A 1A1CA 1FBVA 2MRKA 5AULA 1A08A 5DC9A 2DX0A 4JEGA 3BUMB 3S8OA 1SPSA 2DLZA 4F59A 3US4A 3PFVA 3C7IA 1O4BA 2YU7A 3OB2B 1CWDL 1SHDA 1R1SA 3CD3A 3N8MA 3CWGA 1M61A 1O44A 4LUDA 4WWQA 1O4PA 1BHHA 1OPLA 5I6VA 1FHSA 2QMSA 2L4KA 1A1AA 5IBSA 1AOUF 3OB1B 3QWXX 1Z3KA 3S8LA 4JGHA 2XP1A 1HCTB 3TL0A 2CIAA 2HCKA 1O4OA 1QADA 1RJAA 1BF5A 3K2MA 5HKWA 4OHHA 3VRYA 2EOBA 5EHRA 2H46E 1AD5A 1QG1E 1ZFPE 2DVJA 1LKKA 2DCRA 2BBUA 2LNXA 1MILA 1TZEE 1UUSA 4A4BA 1LUIA 4F5AA 2CRHA 5HKZA 2EO6A 3PQZA 1B47A 2DLYA 2DM0A 5BO4A 4D8KA 1BLJA 3GQIB 1NZLA 4XZ1A 3HHMB 2L3TA 1D4TA 1OPKA 2YSXA 3VRRA 2ECDA 2CS0A 4H34A 1O41A 1YVHA 5HKYA 2RMXA 2B3OA 4FBNA 2EL8A 2JYQA 1LCJA 1D1ZA 1JU5A 4K44A 3VS3A 3PJPA 3VS7A 4M4ZA 1BFJA 1H9OA 4XZ0A 2HUWA 5DC4A 3GXWA 4OHIA 3HCKA 2OQ1A 1GRIA 5EHPA 5AXIA 1OO3A 1D4WA 3VS4A 4DGXA 2MK2A 1IJRA 2C0TA 4FL3A 3ZNIA 2Y1NA 2AOAA 1AYCA 3VRZA 1LUMA 1I3ZA 1X6CA 1O4EA 3QWYA 2Y3AB 4LUEA 2PNBA 2PLDA 3UYOA 2C9WA 1BFIA 4X6SA 3BKBA 2SHPA 1X27A 1A09A
chains in the Genus database with same CATH superfamily
3UF4A 1BM2A 3N7YA 2MQIA 1BG1A 1O4RA 1O4FA 1KC2A 2AOBA 2FCIA 1FBZA 1MW4A 2H5KA 1O4NA 1QCFA 1O4MA 1WQUA 2CI8A 1Y1UA 1M27A 2VIFA 5GJHA 3MAZA 2FO0A 5DF6A 2CR4A 1FYRA 2KNOA 1O4IA 1BHHB 4FL2A 1IS0A 2HMHA 4L1BB 1NZVA 3CBLA 5EG3B 3VROA 1A1BA 5EEQA 3VRPA 1SHAA 2IZVA 2IUGA 1XA6A 1BKMA 1A1EA 4K2RA 2EO3A 5GJIA 1O4KA 2EU0A 3IMDA 4E68A 1AB2A 1YVLA 3OVEA 3S9KA 1CSZA 1O4LA 1F1WA 1AYDA 3N84A 5D0JA 2HDVA 2RSYA 1SHBA 1KA7A 4GL9E 3IN7A 3OP0A 3BUWB 4OHLA 2EYYA 3HIZB 3BUXB 4F5BA 2EYZA 1A81A 1RQQC 1O46A 1HCSB 1O47A 5EELA 1A07A 1Y57A 5KAZA 4ROJA 2LNWA 1O4QA 3OV1A 1O4DA 3VGOA 2GE9A 4K45A 1BMBA 2MC1A 1R1QA 1O4GA 1LCKA 2PLEA 1BHFA 1JYRA 1KSWA 1P13A 3PSKA 1FU5A 3BUNB 2C0OA 1O4AA 3EAZA 5J3XA 2EYVA 4U17A 1CWEA 1O4HA 3EACA 1RPYA 2IUHA 3PLFB 3PSJA 3NHNA 4EIHA 1SKJA 2H8HA 1X0NA 3MXYA 3IN8A 1BKLA 1FU6A 1JWOA 4OHDA 1OO4A 2ETZA 1NRVA 1UURA 4TZIA 2OZOA 1PICA 1GHUA 2ABLA 4H1OA 2HDXA 1K9AA 1LUKA 4JE4A 3TKZA 4NWGA 1AYAA 1O4JA 4EY0A 1CJ1A 2AUGA 2CI9A 3GXXA 4U1PA 3VS5A 4A4CA 1O4CA 4OHEA 2RVFA 2C0IA 4GWFA 1BLKA 1O49A 1FMKA 1SPRA 3KFJA 2RORA 3VS0A 2L6KA 2PNAA 3IMJA 2LQWA 2K7AB 4GPLB 3MXCA 3M7FA 2SRCA 2CBLA 3VRNA 1O43A 3LYVA 1CSYA 4DGPA 2Y1MA 2LCTA 4QSYA 2GSBA 1LUNA 1AYBA 1LKLA 3BUOB 2PTKA 3VRQA 3CXLA 4P9VA 1O42A 4E93A 1F2FA 4NWFA 1G83A 1R1PA 3WA4A 4P9ZA 1O48A 3PS5A 3S8NA 5IBMA 1AOTF 3T04A 2K79B 2KGYA 1TCEA 3VS1A 2IUIA 2LRAA 3VS2A 1JYQA 1KA6A 1JYUA 4K11A 3VS6A 2EKXA 2MRJA 2LQNA 5CDWA 2KK6A 5DC0B 1O45A 1A1CA 1FBVA 2MRKA 5AULA 1A08A 5DC9A 2DX0A 4JEGA 3BUMB 3S8OA 3K2TA 1SPSA 2DLZA 4F59A 3US4A 3PFVA 3C7IA 1O4BA 2YU7A 3OB2B 1CWDL 1SHDA 1R1SA 3CD3A 3N8MA 3CWGA 1M61A 1O44A 4LUDA 4WWQA 1O4PA 1BHHA 1OPLA 5I6VA 1FHSA 2QMSA 2L4KA 1A1AA 5IBSA 1AOUF 3OB1B 3QWXX 1Z3KA 3S8LA 4JGHA 2XP1A 1HCTB 3TL0A 2CIAA 2HCKA 1O4OA 1QADA 1RJAA 1BF5A 3K2MA 5HKWA 4OHHA 3VRYA 2EOBA 5EHRA 2H46E 1AD5A 1QG1E 1ZFPE 2DVJA 1LKKA 2DCRA 2BBUA 2LNXA 1MILA 1TZEE 1UUSA 4A4BA 1LUIA 4F5AA 2CRHA 5HKZA 2EO6A 3PQZA 1B47A 2DLYA 2DM0A 5BO4A 4D8KA 1BLJA 3GQIB 1NZLA 4XZ1A 3HHMB 2L3TA 1D4TA 1OPKA 2YSXA 3VRRA 2ECDA 2CS0A 4H34A 1O41A 1YVHA 5HKYA 2RMXA 2B3OA 4FBNA 2EL8A 2JYQA 1LCJA 1D1ZA 1JU5A 4K44A 3VS3A 3PJPA 3VS7A 4M4ZA 1BFJA 1H9OA 4XZ0A 2HUWA 5DC4A 3GXWA 4OHIA 3HCKA 2OQ1A 1GRIA 5EHPA 5AXIA 1OO3A 1D4WA 3VS4A 4DGXA 2MK2A 1IJRA 2C0TA 4FL3A 3ZNIA 2Y1NA 2AOAA 1AYCA 3VRZA 1LUMA 1I3ZA 1X6CA 1O4EA 3QWYA 2Y3AB 4LUEA 2PNBA 2PLDA 3UYOA 2C9WA 1BFIA 4X6SA 3BKBA 2SHPA 1X27A 1A09A
chains in the Genus database with same CATH topology
3UF4A 1BM2A 3N7YA 2MQIA 1BG1A 1O4RA 1O4FA 1KC2A 2AOBA 2FCIA 1FBZA 1MW4A 2H5KA 1O4NA 1QCFA 1O4MA 1WQUA 2CI8A 1Y1UA 1M27A 2VIFA 5GJHA 3MAZA 2FO0A 5DF6A 2CR4A 1FYRA 2KNOA 1O4IA 1BHHB 4FL2A 1IS0A 2HMHA 4L1BB 1NZVA 3CBLA 5EG3B 3VROA 1A1BA 5EEQA 3VRPA 1SHAA 2IZVA 2IUGA 1XA6A 1BKMA 1A1EA 4K2RA 2EO3A 5GJIA 1O4KA 2EU0A 3IMDA 4E68A 1AB2A 1YVLA 3OVEA 3S9KA 1CSZA 1O4LA 1F1WA 1AYDA 3N84A 5D0JA 2HDVA 2RSYA 1SHBA 1KA7A 4GL9E 3IN7A 3OP0A 3BUWB 4OHLA 2EYYA 3HIZB 3BUXB 4F5BA 2EYZA 1A81A 1RQQC 1O46A 1HCSB 1O47A 5EELA 1A07A 1Y57A 5KAZA 4ROJA 2LNWA 1O4QA 3OV1A 1O4DA 3VGOA 2GE9A 4K45A 1BMBA 2MC1A 1R1QA 1O4GA 1LCKA 2PLEA 1BHFA 1JYRA 1KSWA 1P13A 3PSKA 1FU5A 3BUNB 2C0OA 1O4AA 3EAZA 5J3XA 2EYVA 4U17A 1CWEA 1O4HA 3EACA 1RPYA 2IUHA 3PLFB 3PSJA 3NHNA 4EIHA 1SKJA 2H8HA 1X0NA 3MXYA 3IN8A 1BKLA 1FU6A 1JWOA 4OHDA 1OO4A 2ETZA 1NRVA 1UURA 4TZIA 2OZOA 1PICA 1GHUA 2ABLA 4H1OA 2HDXA 1K9AA 1LUKA 4JE4A 3TKZA 4NWGA 1AYAA 1O4JA 4EY0A 1CJ1A 2AUGA 2CI9A 3GXXA 4U1PA 3VS5A 4A4CA 1O4CA 4OHEA 2RVFA 2C0IA 4GWFA 1BLKA 1O49A 1FMKA 1SPRA 3KFJA 2RORA 3VS0A 2L6KA 2PNAA 3IMJA 2LQWA 2K7AB 4GPLB 3MXCA 3M7FA 2SRCA 2CBLA 3VRNA 1O43A 1CSYA 4DGPA 2Y1MA 2LCTA 4QSYA 2GSBA 1LUNA 1AYBA 1LKLA 3BUOB 2PTKA 3VRQA 3CXLA 4P9VA 1O42A 4E93A 1F2FA 4NWFA 1G83A 1R1PA 3WA4A 4P9ZA 1O48A 3PS5A 3S8NA 5IBMA 1AOTF 3T04A 2K79B 1TCEA 3VS1A 2IUIA 3VS2A 1JYQA 1KA6A 1JYUA 4K11A 3VS6A 2EKXA 2MRJA 2LQNA 5CDWA 2KK6A 5DC0B 1O45A 1A1CA 1FBVA 2MRKA 5AULA 1A08A 5DC9A 2DX0A 4JEGA 3BUMB 3S8OA 1SPSA 2DLZA 4F59A 3US4A 3PFVA 3C7IA 1O4BA 2YU7A 3OB2B 1CWDL 1SHDA 1R1SA 3CD3A 3N8MA 3CWGA 1M61A 1O44A 4LUDA 4WWQA 1O4PA 1BHHA 1OPLA 5I6VA 1FHSA 2QMSA 2L4KA 1A1AA 5IBSA 1AOUF 3OB1B 3QWXX 1Z3KA 3S8LA 4JGHA 2XP1A 1HCTB 3TL0A 2CIAA 2HCKA 1O4OA 1QADA 1RJAA 1BF5A 3K2MA 5HKWA 4OHHA 3VRYA 2EOBA 5EHRA 2H46E 1AD5A 1QG1E 1ZFPE 2DVJA 1LKKA 2DCRA 2BBUA 2LNXA 1MILA 1TZEE 1UUSA 4A4BA 1LUIA 4F5AA 2CRHA 5HKZA 2EO6A 3PQZA 1B47A 2DLYA 2DM0A 5BO4A 4D8KA 1BLJA 3GQIB 1NZLA 4XZ1A 3HHMB 2L3TA 1D4TA 1OPKA 2YSXA 3VRRA 2ECDA 2CS0A 4H34A 1O41A 1YVHA 5HKYA 2RMXA 2B3OA 4FBNA 2EL8A 2JYQA 1LCJA 1D1ZA 1JU5A 4K44A 3VS3A 3PJPA 3VS7A 4M4ZA 1BFJA 1H9OA 4XZ0A 2HUWA 5DC4A 3GXWA 4OHIA 3HCKA 2OQ1A 1GRIA 5EHPA 5AXIA 1OO3A 1D4WA 3VS4A 4DGXA 2MK2A 1IJRA 2C0TA 4FL3A 3ZNIA 2Y1NA 2AOAA 1AYCA 3VRZA 1LUMA 1I3ZA 1X6CA 1O4EA 3QWYA 2Y3AB 4LUEA 2PNBA 2PLDA 3UYOA 2C9WA 1BFIA 4X6SA 3BKBA 2SHPA 1X27A 1A09A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UF4 A;  1BM2 A;  3N7Y A;  2MQI A;  1BG1 A;  1O4R A;  1O4F A;  1KC2 A;  2AOB A;  2FCI A;  1FBZ A;  1MW4 A;  2H5K A;  1O4N A;  1QCF A;  1O4M A;  1WQU A;  2CI8 A;  1Y1U A;  1M27 A;  2VIF A;  5GJH A;  3MAZ A;  2FO0 A;  5DF6 A;  2CR4 A;  1FYR A;  2KNO A;  1O4I A;  1BHH B;  4FL2 A;  1IS0 A;  2HMH A;  4L1B B;  1NZV A;  3CBL A;  5EG3 B;  3VRO A;  1A1B A;  5EEQ A;  3VRP A;  1SHA A;  2IZV A;  2IUG A;  1XA6 A;  1BKM A;  1A1E A;  4K2R A;  2EO3 A;  5GJI A;  1O4K A;  2EU0 A;  3IMD A;  4E68 A;  1AB2 A;  1YVL A;  3OVE A;  3S9K A;  1CSZ A;  1O4L A;  1F1W A;  1AYD A;  3N84 A;  5D0J A;  2HDV A;  2RSY A;  1SHB A;  1KA7 A;  4GL9 E;  3IN7 A;  3OP0 A;  3BUW B;  4OHL A;  2EYY A;  3HIZ B;  3BUX B;  4F5B A;  2EYZ A;  1A81 A;  1RQQ C;  1O46 A;  1HCS B;  1O47 A;  5EEL A;  1A07 A;  1Y57 A;  5KAZ A;  4ROJ A;  2LNW A;  1O4Q A;  3OV1 A;  1O4D A;  3VGO A;  2GE9 A;  4K45 A;  1BMB A;  2MC1 A;  1R1Q A;  1O4G A;  1LCK A;  2PLE A;  1BHF A;  1JYR A;  1KSW A;  1P13 A;  3PSK A;  1FU5 A;  3BUN B;  2C0O A;  1O4A A;  3EAZ A;  5J3X A;  2EYV A;  4U17 A;  1CWE A;  1O4H A;  3EAC A;  1RPY A;  2IUH A;  3PLF B;  3PSJ A;  3NHN A;  4EIH A;  1SKJ A;  2H8H A;  1X0N A;  3MXY A;  3IN8 A;  1BKL A;  1FU6 A;  1JWO A;  4OHD A;  1OO4 A;  2ETZ A;  1NRV A;  1UUR A;  4TZI A;  2OZO A;  1PIC A;  1GHU A;  2ABL A;  4H1O A;  2HDX A;  1K9A A;  1LUK A;  4JE4 A;  3TKZ A;  4NWG A;  1AYA A;  1O4J A;  4EY0 A;  1CJ1 A;  2AUG A;  2CI9 A;  3GXX A;  4U1P A;  3VS5 A;  4A4C A;  1O4C A;  4OHE A;  2RVF A;  2C0I A;  4GWF A;  1BLK A;  1O49 A;  1FMK A;  1SPR A;  3KFJ A;  2ROR A;  3VS0 A;  2L6K A;  2PNA A;  3IMJ A;  2LQW A;  2K7A B;  4GPL B;  3MXC A;  3M7F A;  2SRC A;  2CBL A;  3VRN A;  1O43 A;  1CSY A;  4DGP A;  2Y1M A;  2LCT A;  4QSY A;  2GSB A;  1LUN A;  1AYB A;  1LKL A;  3BUO B;  2PTK A;  3VRQ A;  3CXL A;  4P9V A;  1O42 A;  4E93 A;  1F2F A;  4NWF A;  1G83 A;  1R1P A;  3WA4 A;  4P9Z A;  1O48 A;  3PS5 A;  3S8N A;  5IBM A;  1AOT F;  3T04 A;  2K79 B;  1TCE A;  3VS1 A;  2IUI A;  3VS2 A;  1JYQ A;  1KA6 A;  1JYU A;  4K11 A;  3VS6 A;  2EKX A;  2MRJ A;  2LQN A;  5CDW A;  2KK6 A;  5DC0 B;  1O45 A;  1A1C A;  1FBV A;  2MRK A;  5AUL A;  1A08 A;  5DC9 A;  2DX0 A;  4JEG A;  3BUM B;  3S8O A;  1SPS A;  2DLZ A;  4F59 A;  3US4 A;  3PFV A;  3C7I A;  1O4B A;  2YU7 A;  3OB2 B;  1CWD L;  1SHD A;  1R1S A;  3CD3 A;  3N8M A;  3CWG A;  1M61 A;  1O44 A;  4LUD A;  4WWQ A;  1O4P A;  1BHH A;  1OPL A;  5I6V A;  1FHS A;  2QMS A;  2L4K A;  1A1A A;  5IBS A;  1AOU F;  3OB1 B;  3QWX X;  1Z3K A;  3S8L A;  4JGH A;  2XP1 A;  1HCT B;  3TL0 A;  2CIA A;  2HCK A;  1O4O A;  1QAD A;  1RJA A;  1BF5 A;  3K2M A;  5HKW A;  4OHH A;  3VRY A;  2EOB A;  5EHR A;  2H46 E;  1AD5 A;  1QG1 E;  1ZFP E;  2DVJ A;  1LKK A;  2DCR A;  2BBU A;  2LNX A;  1MIL A;  1TZE E;  1UUS A;  4A4B A;  1LUI A;  4F5A A;  2CRH A;  5HKZ A;  2EO6 A;  3PQZ A;  1B47 A;  2DLY A;  2DM0 A;  5BO4 A;  4D8K A;  1BLJ A;  3GQI B;  1NZL A;  4XZ1 A;  3HHM B;  2L3T A;  1D4T A;  1OPK A;  2YSX A;  3VRR A;  2ECD A;  2CS0 A;  4H34 A;  1O41 A;  1YVH A;  5HKY A;  2RMX A;  2B3O A;  4FBN A;  2EL8 A;  2JYQ A;  1LCJ A;  1D1Z A;  1JU5 A;  4K44 A;  3VS3 A;  3PJP A;  3VS7 A;  4M4Z A;  1BFJ A;  1H9O A;  4XZ0 A;  2HUW A;  5DC4 A;  3GXW A;  4OHI A;  3HCK A;  2OQ1 A;  1GRI A;  5EHP A;  5AXI A;  1OO3 A;  1D4W A;  3VS4 A;  4DGX A;  2MK2 A;  1IJR A;  2C0T A;  4FL3 A;  3ZNI A;  2Y1N A;  2AOA A;  1AYC A;  3VRZ A;  1LUM A;  1I3Z A;  1X6C A;  1O4E A;  3QWY A;  2Y3A B;  4LUE A;  2PNB A;  2PLD A;  3UYO A;  2C9W A;  1BFI A;  4X6S A;  3BKB A;  2SHP A;  1X27 A;  1A09 A; 
#chains in the Genus database with same CATH topology
 3UF4 A;  1BM2 A;  3N7Y A;  2MQI A;  1BG1 A;  1O4R A;  1O4F A;  1KC2 A;  2AOB A;  2FCI A;  1FBZ A;  1MW4 A;  2H5K A;  1O4N A;  1QCF A;  1O4M A;  1WQU A;  2CI8 A;  1Y1U A;  1M27 A;  2VIF A;  5GJH A;  3MAZ A;  2FO0 A;  5DF6 A;  2CR4 A;  1FYR A;  2KNO A;  1O4I A;  1BHH B;  4FL2 A;  1IS0 A;  2HMH A;  4L1B B;  1NZV A;  3CBL A;  5EG3 B;  3VRO A;  1A1B A;  5EEQ A;  3VRP A;  1SHA A;  2IZV A;  2IUG A;  1XA6 A;  1BKM A;  1A1E A;  4K2R A;  2EO3 A;  5GJI A;  1O4K A;  2EU0 A;  3IMD A;  4E68 A;  1AB2 A;  1YVL A;  3OVE A;  3S9K A;  1CSZ A;  1O4L A;  1F1W A;  1AYD A;  3N84 A;  5D0J A;  2HDV A;  2RSY A;  1SHB A;  1KA7 A;  4GL9 E;  3IN7 A;  3OP0 A;  3BUW B;  4OHL A;  2EYY A;  3HIZ B;  3BUX B;  4F5B A;  2EYZ A;  1A81 A;  1RQQ C;  1O46 A;  1HCS B;  1O47 A;  5EEL A;  1A07 A;  1Y57 A;  5KAZ A;  4ROJ A;  2LNW A;  1O4Q A;  3OV1 A;  1O4D A;  3VGO A;  2GE9 A;  4K45 A;  1BMB A;  2MC1 A;  1R1Q A;  1O4G A;  1LCK A;  2PLE A;  1BHF A;  1JYR A;  1KSW A;  1P13 A;  3PSK A;  1FU5 A;  3BUN B;  2C0O A;  1O4A A;  3EAZ A;  5J3X A;  2EYV A;  4U17 A;  1CWE A;  1O4H A;  3EAC A;  1RPY A;  2IUH A;  3PLF B;  3PSJ A;  3NHN A;  4EIH A;  1SKJ A;  2H8H A;  1X0N A;  3MXY A;  3IN8 A;  1BKL A;  1FU6 A;  1JWO A;  4OHD A;  1OO4 A;  2ETZ A;  1NRV A;  1UUR A;  4TZI A;  2OZO A;  1PIC A;  1GHU A;  2ABL A;  4H1O A;  2HDX A;  1K9A A;  1LUK A;  4JE4 A;  3TKZ A;  4NWG A;  1AYA A;  1O4J A;  4EY0 A;  1CJ1 A;  2AUG A;  2CI9 A;  3GXX A;  4U1P A;  3VS5 A;  4A4C A;  1O4C A;  4OHE A;  2RVF A;  2C0I A;  4GWF A;  1BLK A;  1O49 A;  1FMK A;  1SPR A;  3KFJ A;  2ROR A;  3VS0 A;  2L6K A;  2PNA A;  3IMJ A;  2LQW A;  2K7A B;  4GPL B;  3MXC A;  3M7F A;  2SRC A;  2CBL A;  3VRN A;  1O43 A;  3LYV A;  1CSY A;  4DGP A;  2Y1M A;  2LCT A;  4QSY A;  2GSB A;  1LUN A;  1AYB A;  1LKL A;  3BUO B;  2PTK A;  3VRQ A;  3CXL A;  4P9V A;  1O42 A;  4E93 A;  1F2F A;  4NWF A;  1G83 A;  1R1P A;  3WA4 A;  4P9Z A;  1O48 A;  3PS5 A;  3S8N A;  5IBM A;  1AOT F;  3T04 A;  2K79 B;  2KGY A;  1TCE A;  3VS1 A;  2IUI A;  2LRA A;  3VS2 A;  1JYQ A;  1KA6 A;  1JYU A;  4K11 A;  3VS6 A;  2EKX A;  2MRJ A;  2LQN A;  5CDW A;  2KK6 A;  5DC0 B;  1O45 A;  1A1C A;  1FBV A;  2MRK A;  5AUL A;  1A08 A;  5DC9 A;  2DX0 A;  4JEG A;  3BUM B;  3S8O A;  3K2T A;  1SPS A;  2DLZ A;  4F59 A;  3US4 A;  3PFV A;  3C7I A;  1O4B A;  2YU7 A;  3OB2 B;  1CWD L;  1SHD A;  1R1S A;  3CD3 A;  3N8M A;  3CWG A;  1M61 A;  1O44 A;  4LUD A;  4WWQ A;  1O4P A;  1BHH A;  1OPL A;  5I6V A;  1FHS A;  2QMS A;  2L4K A;  1A1A A;  5IBS A;  1AOU F;  3OB1 B;  3QWX X;  1Z3K A;  3S8L A;  4JGH A;  2XP1 A;  1HCT B;  3TL0 A;  2CIA A;  2HCK A;  1O4O A;  1QAD A;  1RJA A;  1BF5 A;  3K2M A;  5HKW A;  4OHH A;  3VRY A;  2EOB A;  5EHR A;  2H46 E;  1AD5 A;  1QG1 E;  1ZFP E;  2DVJ A;  1LKK A;  2DCR A;  2BBU A;  2LNX A;  1MIL A;  1TZE E;  1UUS A;  4A4B A;  1LUI A;  4F5A A;  2CRH A;  5HKZ A;  2EO6 A;  3PQZ A;  1B47 A;  2DLY A;  2DM0 A;  5BO4 A;  4D8K A;  1BLJ A;  3GQI B;  1NZL A;  4XZ1 A;  3HHM B;  2L3T A;  1D4T A;  1OPK A;  2YSX A;  3VRR A;  2ECD A;  2CS0 A;  4H34 A;  1O41 A;  1YVH A;  5HKY A;  2RMX A;  2B3O A;  4FBN A;  2EL8 A;  2JYQ A;  1LCJ A;  1D1Z A;  1JU5 A;  4K44 A;  3VS3 A;  3PJP A;  3VS7 A;  4M4Z A;  1BFJ A;  1H9O A;  4XZ0 A;  2HUW A;  5DC4 A;  3GXW A;  4OHI A;  3HCK A;  2OQ1 A;  1GRI A;  5EHP A;  5AXI A;  1OO3 A;  1D4W A;  3VS4 A;  4DGX A;  2MK2 A;  1IJR A;  2C0T A;  4FL3 A;  3ZNI A;  2Y1N A;  2AOA A;  1AYC A;  3VRZ A;  1LUM A;  1I3Z A;  1X6C A;  1O4E A;  3QWY A;  2Y3A B;  4LUE A;  2PNB A;  2PLD A;  3UYO A;  2C9W A;  1BFI A;  4X6S A;  3BKB A;  2SHP A;  1X27 A;  1A09 A; 
#chains in the Genus database with same CATH homology
 3UF4 A;  1BM2 A;  3N7Y A;  2MQI A;  1BG1 A;  1O4R A;  1O4F A;  1KC2 A;  2AOB A;  2FCI A;  1FBZ A;  1MW4 A;  2H5K A;  1O4N A;  1QCF A;  1O4M A;  1WQU A;  2CI8 A;  1Y1U A;  1M27 A;  2VIF A;  5GJH A;  3MAZ A;  2FO0 A;  5DF6 A;  2CR4 A;  1FYR A;  2KNO A;  1O4I A;  1BHH B;  4FL2 A;  1IS0 A;  2HMH A;  4L1B B;  1NZV A;  3CBL A;  5EG3 B;  3VRO A;  1A1B A;  5EEQ A;  3VRP A;  1SHA A;  2IZV A;  2IUG A;  1XA6 A;  1BKM A;  1A1E A;  4K2R A;  2EO3 A;  5GJI A;  1O4K A;  2EU0 A;  3IMD A;  4E68 A;  1AB2 A;  1YVL A;  3OVE A;  3S9K A;  1CSZ A;  1O4L A;  1F1W A;  1AYD A;  3N84 A;  5D0J A;  2HDV A;  2RSY A;  1SHB A;  1KA7 A;  4GL9 E;  3IN7 A;  3OP0 A;  3BUW B;  4OHL A;  2EYY A;  3HIZ B;  3BUX B;  4F5B A;  2EYZ A;  1A81 A;  1RQQ C;  1O46 A;  1HCS B;  1O47 A;  5EEL A;  1A07 A;  1Y57 A;  5KAZ A;  4ROJ A;  2LNW A;  1O4Q A;  3OV1 A;  1O4D A;  3VGO A;  2GE9 A;  4K45 A;  1BMB A;  2MC1 A;  1R1Q A;  1O4G A;  1LCK A;  2PLE A;  1BHF A;  1JYR A;  1KSW A;  1P13 A;  3PSK A;  1FU5 A;  3BUN B;  2C0O A;  1O4A A;  3EAZ A;  5J3X A;  2EYV A;  4U17 A;  1CWE A;  1O4H A;  3EAC A;  1RPY A;  2IUH A;  3PLF B;  3PSJ A;  3NHN A;  4EIH A;  1SKJ A;  2H8H A;  1X0N A;  3MXY A;  3IN8 A;  1BKL A;  1FU6 A;  1JWO A;  4OHD A;  1OO4 A;  2ETZ A;  1NRV A;  1UUR A;  4TZI A;  2OZO A;  1PIC A;  1GHU A;  2ABL A;  4H1O A;  2HDX A;  1K9A A;  1LUK A;  4JE4 A;  3TKZ A;  4NWG A;  1AYA A;  1O4J A;  4EY0 A;  1CJ1 A;  2AUG A;  2CI9 A;  3GXX A;  4U1P A;  3VS5 A;  4A4C A;  1O4C A;  4OHE A;  2RVF A;  2C0I A;  4GWF A;  1BLK A;  1O49 A;  1FMK A;  1SPR A;  3KFJ A;  2ROR A;  3VS0 A;  2L6K A;  2PNA A;  3IMJ A;  2LQW A;  2K7A B;  4GPL B;  3MXC A;  3M7F A;  2SRC A;  2CBL A;  3VRN A;  1O43 A;  1CSY A;  4DGP A;  2Y1M A;  2LCT A;  4QSY A;  2GSB A;  1LUN A;  1AYB A;  1LKL A;  3BUO B;  2PTK A;  3VRQ A;  3CXL A;  4P9V A;  1O42 A;  4E93 A;  1F2F A;  4NWF A;  1G83 A;  1R1P A;  3WA4 A;  4P9Z A;  1O48 A;  3PS5 A;  3S8N A;  5IBM A;  1AOT F;  3T04 A;  2K79 B;  1TCE A;  3VS1 A;  2IUI A;  3VS2 A;  1JYQ A;  1KA6 A;  1JYU A;  4K11 A;  3VS6 A;  2EKX A;  2MRJ A;  2LQN A;  5CDW A;  2KK6 A;  5DC0 B;  1O45 A;  1A1C A;  1FBV A;  2MRK A;  5AUL A;  1A08 A;  5DC9 A;  2DX0 A;  4JEG A;  3BUM B;  3S8O A;  1SPS A;  2DLZ A;  4F59 A;  3US4 A;  3PFV A;  3C7I A;  1O4B A;  2YU7 A;  3OB2 B;  1CWD L;  1SHD A;  1R1S A;  3CD3 A;  3N8M A;  3CWG A;  1M61 A;  1O44 A;  4LUD A;  4WWQ A;  1O4P A;  1BHH A;  1OPL A;  5I6V A;  1FHS A;  2QMS A;  2L4K A;  1A1A A;  5IBS A;  1AOU F;  3OB1 B;  3QWX X;  1Z3K A;  3S8L A;  4JGH A;  2XP1 A;  1HCT B;  3TL0 A;  2CIA A;  2HCK A;  1O4O A;  1QAD A;  1RJA A;  1BF5 A;  3K2M A;  5HKW A;  4OHH A;  3VRY A;  2EOB A;  5EHR A;  2H46 E;  1AD5 A;  1QG1 E;  1ZFP E;  2DVJ A;  1LKK A;  2DCR A;  2BBU A;  2LNX A;  1MIL A;  1TZE E;  1UUS A;  4A4B A;  1LUI A;  4F5A A;  2CRH A;  5HKZ A;  2EO6 A;  3PQZ A;  1B47 A;  2DLY A;  2DM0 A;  5BO4 A;  4D8K A;  1BLJ A;  3GQI B;  1NZL A;  4XZ1 A;  3HHM B;  2L3T A;  1D4T A;  1OPK A;  2YSX A;  3VRR A;  2ECD A;  2CS0 A;  4H34 A;  1O41 A;  1YVH A;  5HKY A;  2RMX A;  2B3O A;  4FBN A;  2EL8 A;  2JYQ A;  1LCJ A;  1D1Z A;  1JU5 A;  4K44 A;  3VS3 A;  3PJP A;  3VS7 A;  4M4Z A;  1BFJ A;  1H9O A;  4XZ0 A;  2HUW A;  5DC4 A;  3GXW A;  4OHI A;  3HCK A;  2OQ1 A;  1GRI A;  5EHP A;  5AXI A;  1OO3 A;  1D4W A;  3VS4 A;  4DGX A;  2MK2 A;  1IJR A;  2C0T A;  4FL3 A;  3ZNI A;  2Y1N A;  2AOA A;  1AYC A;  3VRZ A;  1LUM A;  1I3Z A;  1X6C A;  1O4E A;  3QWY A;  2Y3A B;  4LUE A;  2PNB A;  2PLD A;  3UYO A;  2C9W A;  1BFI A;  4X6S A;  3BKB A;  2SHP A;  1X27 A;  1A09 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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