1O4RA

Crystal structure of sh2 in complex with ru78783.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 27
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4rA00
2YSXA 1KA7A 1HCTB 3KFJA 1FHSA 2Y1NA 1AYBA 2EYZA 2L6KA 3IN8A 1O4PA 5GJIA 2C0IA 3VS6A 1X27A 1HCSB 3S8LA 2RORA 2YU7A 2HDXA 3VS2A 2FO0A 2LQNA 2RVFA 2Y3AB 3N84A 2EO6A 1NZLA 1NRVA 2PTKA 4P9ZA 2IUGA 1IJRA 3N7YA 1O41A 2AOBA 4A4CA 1BHHA 1OPKA 3VS0A 1O4QA 3VRQA 3BUMB 4F59A 5IBMA 1BKLA 4NWFA 1Y1UA 3VS4A 3PLFB 1YVHA 1O4JA 5DF6A 1FU6A 4K45A 2DLYA 1O43A 2OZOA 4JEGA 5HKYA 3OB2B 1B47A 4LUDA 1UURA 2DM0A 5CDWA 4NWGA 4GPLB 3VS5A 4DGPA 3MXYA 4WWQA 3IN7A 3CD3A 3BUWB 3ZNIA 1O4NA 1BF5A 2EKXA 3PJPA 4LUEA 3VRRA 5DC0B 1RJAA 1AOTF 4E93A 1OO4A 3EAZA 2MQIA 3VRNA 2LNXA 5D0JA 2RMXA 3GXWA 4FL2A 4M4ZA 1MW4A 1GRIA 1O4RA 3OP0A 4EIHA 1CSZA 5EG3B 2EYVA 5EHRA 1IS0A 4TZIA 1BLKA 3N8MA 1AB2A 2LNWA 1O4GA 1CWEA 2QMSA 3OVEA 3S8OA 1SHBA 2GSBA 3PS5A 3VS3A 2MC1A 1YVLA 3GQIB 1ZFPE 1O42A 3VRZA 3VS1A 5IBSA 1X0NA 1X6CA 1O4IA 1WQUA 3BKBA 1R1PA 4OHIA 4FL3A 3CBLA 2L3TA 4L1BB 2CS0A 2BBUA 2OQ1A 1O46A 3TKZA 4P9VA 2MRKA 2PLEA 4EY0A 4ROJA 1BFJA 5HKZA 1O45A 1KA6A 1QCFA 1I3ZA 4E68A 1TZEE 2SHPA 2GE9A 3UF4A 2Y1MA 4H34A 5J3XA 1FYRA 2HMHA 1JYUA 2CBLA 1F2FA 1D4WA 2EOBA 2EYYA 3OB1B 4JGHA 2H5KA 1FU5A 1JYQA 1SHDA 5I6VA 1O4DA 4A4BA 3IMJA 2PNAA 1O4HA 4D8KA 3HHMB 3QWXX 3GXXA 1KC2A 2DLZA 1O4EA 1PICA 3QWYA 1P13A 3PSKA 1CJ1A 1UUSA 3VGOA 4XZ1A 1O4FA 2AOAA 2XP1A 5EELA 1R1QA 4GL9E 3K2MA 1O4LA 1SPRA 1LUIA 1BG1A 3C7IA 1KSWA 1LKLA 1O4MA 2ECDA 1A1AA 1K9AA 2DCRA 1XA6A 2B3OA 1D4TA 2CI8A 3VRYA 2SRCA 4F5AA 1BKMA 3IMDA 4DGXA 1SPSA 2H46E 1A1EA 2CRHA 1GHUA 2DVJA 1RPYA 2C0TA 1OPLA 2HCKA 2PNBA 1FBVA 2FCIA 1G83A 1NZVA 4OHDA 1FMKA 1O44A 3BUOB 1BM2A 2EL8A 1BHHB 1CWDL 2RSYA 4OHEA 3EACA 2L4KA 2C9WA 4K2RA 4K11A 3MAZA 2IZVA 2HDVA 1LKKA 3CXLA 3VRPA 4OHLA 3UYOA 1F1WA 3BUNB 1AOUF 1O4AA 2JYQA 3T04A 1LUKA 2HUWA 4JE4A 1AYDA 1OO3A 1O4OA 1A1BA 2MRJA 1LCKA 3NHNA 3HIZB 2PLDA 1JU5A 2IUIA 3VROA 1AYCA 1O47A 4XZ0A 4GWFA 1H9OA 1A08A 1SKJA 1M27A 3CWGA 3BUXB 2LCTA 4U17A 2VIFA 1JYRA 1Y57A 1RQQC 5DC9A 1Z3KA 1TCEA 5HKWA 1BMBA 1AD5A 2K79B 1CSYA 2CR4A 4U1PA 4OHHA 5EEQA 1FBZA 1LUMA 2LQWA 2ABLA 3VS7A 1AYAA 2AUGA 2KNOA 3TL0A 1R1SA 3PQZA 1O4CA 4H1OA 5AULA 5AXIA 3HCKA 3MXCA 1SHAA 1LCJA 3US4A 3OV1A 1A81A 2CIAA 1M61A 4K44A 1BFIA 1A1CA 2C0OA 2K7AB 5DC4A 1JWOA 2H8HA 3WA4A 1MILA 2DX0A 2EU0A 3M7FA 5GJHA 5KAZA 1BHFA 2IUHA 1BLJA 1O4BA 3S8NA 1O49A 1O4KA 4FBNA 4QSYA 1QG1E 1A07A 3S9KA 1D1ZA 1LUNA 5BO4A 2CI9A 1QADA 3PFVA 4X6SA 1A09A 1O48A 3PSJA 2KK6A 2EO3A 4F5BA 2ETZA 5EHPA 2MK2A
chains in the Genus database with same CATH superfamily
2YSXA 1KA7A 1HCTB 3KFJA 1FHSA 2Y1NA 1AYBA 2EYZA 2L6KA 3IN8A 1O4PA 5GJIA 2C0IA 3VS6A 1X27A 1HCSB 3S8LA 2RORA 2YU7A 2HDXA 3VS2A 2FO0A 2LQNA 2RVFA 2Y3AB 3N84A 2EO6A 1NZLA 1NRVA 2PTKA 4P9ZA 2IUGA 1IJRA 3N7YA 1O41A 2AOBA 4A4CA 1BHHA 1OPKA 3VS0A 1O4QA 3VRQA 3BUMB 4F59A 5IBMA 1BKLA 4NWFA 1Y1UA 3VS4A 3PLFB 1YVHA 1O4JA 5DF6A 1FU6A 4K45A 2DLYA 1O43A 2OZOA 4JEGA 5HKYA 3OB2B 1B47A 4LUDA 1UURA 2DM0A 5CDWA 4NWGA 4GPLB 3VS5A 4DGPA 3MXYA 4WWQA 3IN7A 3CD3A 3BUWB 3ZNIA 1O4NA 1BF5A 2EKXA 3PJPA 4LUEA 3VRRA 5DC0B 1RJAA 1AOTF 4E93A 1OO4A 3EAZA 2MQIA 3VRNA 3LYVA 2LNXA 5D0JA 2RMXA 3GXWA 4FL2A 4M4ZA 1MW4A 1GRIA 1O4RA 3OP0A 4EIHA 1CSZA 5EG3B 2EYVA 5EHRA 1IS0A 4TZIA 1BLKA 3N8MA 1AB2A 2LNWA 1O4GA 1CWEA 2QMSA 3OVEA 3S8OA 1SHBA 2GSBA 3PS5A 3VS3A 2MC1A 1YVLA 3GQIB 1ZFPE 1O42A 3VRZA 3VS1A 5IBSA 1X0NA 1X6CA 1O4IA 1WQUA 3BKBA 1R1PA 4OHIA 4FL3A 3CBLA 2L3TA 4L1BB 2CS0A 2BBUA 2OQ1A 1O46A 3TKZA 4P9VA 2MRKA 2PLEA 4EY0A 4ROJA 1BFJA 5HKZA 1O45A 1KA6A 1QCFA 1I3ZA 4E68A 1TZEE 2SHPA 2GE9A 3UF4A 2Y1MA 4H34A 5J3XA 1FYRA 2HMHA 1JYUA 2CBLA 1F2FA 1D4WA 2EOBA 2EYYA 3OB1B 4JGHA 2H5KA 1FU5A 1JYQA 1SHDA 5I6VA 1O4DA 4A4BA 2LRAA 2PNAA 1O4HA 3IMJA 4D8KA 3HHMB 3QWXX 3GXXA 1KC2A 2DLZA 1O4EA 1PICA 3QWYA 1P13A 3PSKA 1CJ1A 1UUSA 3VGOA 4XZ1A 1O4FA 2AOAA 2XP1A 5EELA 1R1QA 4GL9E 3K2MA 1O4LA 1SPRA 1LUIA 1BG1A 3C7IA 1KSWA 1LKLA 1O4MA 2ECDA 1A1AA 1K9AA 2DCRA 1XA6A 2B3OA 1D4TA 2CI8A 3VRYA 2SRCA 4F5AA 1BKMA 3IMDA 4DGXA 1SPSA 2H46E 1A1EA 2CRHA 1GHUA 2DVJA 1RPYA 2C0TA 1OPLA 2HCKA 2PNBA 1FBVA 2FCIA 1G83A 1NZVA 4OHDA 1FMKA 1O44A 3BUOB 1BM2A 2EL8A 1BHHB 1CWDL 2RSYA 4OHEA 3EACA 2L4KA 2C9WA 4K2RA 4K11A 3MAZA 2IZVA 2HDVA 1LKKA 3CXLA 3VRPA 3K2TA 4OHLA 3UYOA 1F1WA 3BUNB 1AOUF 1O4AA 2JYQA 3T04A 1LUKA 2HUWA 4JE4A 1AYDA 1OO3A 1O4OA 1A1BA 2MRJA 1LCKA 3NHNA 3HIZB 2PLDA 1JU5A 2IUIA 3VROA 1AYCA 2KGYA 1O47A 4XZ0A 4GWFA 1H9OA 1A08A 1SKJA 1M27A 3CWGA 3BUXB 2LCTA 4U17A 2VIFA 1JYRA 1Y57A 1RQQC 5DC9A 1Z3KA 1TCEA 5HKWA 1BMBA 1AD5A 2K79B 1CSYA 2CR4A 4U1PA 4OHHA 5EEQA 1FBZA 1LUMA 2LQWA 2ABLA 3VS7A 1AYAA 2AUGA 2KNOA 3TL0A 1R1SA 3PQZA 1O4CA 4H1OA 5AULA 5AXIA 3HCKA 3MXCA 1SHAA 1LCJA 3US4A 3OV1A 1A81A 2CIAA 1M61A 4K44A 1BFIA 1A1CA 2C0OA 2K7AB 5DC4A 1JWOA 2H8HA 3WA4A 1MILA 2DX0A 2EU0A 3M7FA 5GJHA 5KAZA 1BHFA 2IUHA 1BLJA 1O4BA 3S8NA 1O49A 1O4KA 4FBNA 4QSYA 1QG1E 1A07A 3S9KA 1D1ZA 1LUNA 5BO4A 2CI9A 1QADA 3PFVA 4X6SA 1A09A 1O48A 3PSJA 2KK6A 2EO3A 4F5BA 2ETZA 5EHPA 2MK2A
chains in the Genus database with same CATH topology
2YSXA 1KA7A 1HCTB 3KFJA 1FHSA 2Y1NA 1AYBA 2EYZA 2L6KA 3IN8A 1O4PA 5GJIA 2C0IA 3VS6A 1X27A 1HCSB 3S8LA 2RORA 2YU7A 2HDXA 3VS2A 2FO0A 2LQNA 2RVFA 2Y3AB 3N84A 2EO6A 1NZLA 1NRVA 2PTKA 4P9ZA 2IUGA 1IJRA 3N7YA 1O41A 2AOBA 4A4CA 1BHHA 1OPKA 3VS0A 1O4QA 3VRQA 3BUMB 4F59A 5IBMA 1BKLA 4NWFA 1Y1UA 3VS4A 3PLFB 1YVHA 1O4JA 5DF6A 1FU6A 4K45A 2DLYA 1O43A 2OZOA 4JEGA 5HKYA 3OB2B 1B47A 4LUDA 1UURA 2DM0A 5CDWA 4NWGA 4GPLB 3VS5A 4DGPA 3MXYA 4WWQA 3IN7A 3CD3A 3BUWB 3ZNIA 1O4NA 1BF5A 2EKXA 3PJPA 4LUEA 3VRRA 5DC0B 1RJAA 1AOTF 4E93A 1OO4A 3EAZA 2MQIA 3VRNA 2LNXA 5D0JA 2RMXA 3GXWA 4FL2A 4M4ZA 1MW4A 1GRIA 1O4RA 3OP0A 4EIHA 1CSZA 5EG3B 2EYVA 5EHRA 1IS0A 4TZIA 1BLKA 3N8MA 1AB2A 2LNWA 1O4GA 1CWEA 2QMSA 3OVEA 3S8OA 1SHBA 2GSBA 3PS5A 3VS3A 2MC1A 1YVLA 3GQIB 1ZFPE 1O42A 3VRZA 3VS1A 5IBSA 1X0NA 1X6CA 1O4IA 1WQUA 3BKBA 1R1PA 4OHIA 4FL3A 3CBLA 2L3TA 4L1BB 2CS0A 2BBUA 2OQ1A 1O46A 3TKZA 4P9VA 2MRKA 2PLEA 4EY0A 4ROJA 1BFJA 5HKZA 1O45A 1KA6A 1QCFA 1I3ZA 4E68A 1TZEE 2SHPA 2GE9A 3UF4A 2Y1MA 4H34A 5J3XA 1FYRA 2HMHA 1JYUA 2CBLA 1F2FA 1D4WA 2EOBA 2EYYA 3OB1B 4JGHA 2H5KA 1FU5A 1JYQA 1SHDA 5I6VA 1O4DA 4A4BA 3IMJA 2PNAA 1O4HA 4D8KA 3HHMB 3QWXX 3GXXA 1KC2A 2DLZA 1O4EA 1PICA 3QWYA 1P13A 3PSKA 1CJ1A 1UUSA 3VGOA 4XZ1A 1O4FA 2AOAA 2XP1A 5EELA 1R1QA 4GL9E 3K2MA 1O4LA 1SPRA 1LUIA 1BG1A 3C7IA 1KSWA 1LKLA 1O4MA 2ECDA 1A1AA 1K9AA 2DCRA 1XA6A 2B3OA 1D4TA 2CI8A 3VRYA 2SRCA 4F5AA 1BKMA 3IMDA 4DGXA 1SPSA 2H46E 1A1EA 2CRHA 1GHUA 2DVJA 1RPYA 2C0TA 1OPLA 2HCKA 2PNBA 1FBVA 2FCIA 1G83A 1NZVA 4OHDA 1FMKA 1O44A 3BUOB 1BM2A 2EL8A 1BHHB 1CWDL 2RSYA 4OHEA 3EACA 2L4KA 2C9WA 4K2RA 4K11A 3MAZA 2IZVA 2HDVA 1LKKA 3CXLA 3VRPA 4OHLA 3UYOA 1F1WA 3BUNB 1AOUF 1O4AA 2JYQA 3T04A 1LUKA 2HUWA 4JE4A 1AYDA 1OO3A 1O4OA 1A1BA 2MRJA 1LCKA 3NHNA 3HIZB 2PLDA 1JU5A 2IUIA 3VROA 1AYCA 1O47A 4XZ0A 4GWFA 1H9OA 1A08A 1SKJA 1M27A 3CWGA 3BUXB 2LCTA 4U17A 2VIFA 1JYRA 1Y57A 1RQQC 5DC9A 1Z3KA 1TCEA 5HKWA 1BMBA 1AD5A 2K79B 1CSYA 2CR4A 4U1PA 4OHHA 5EEQA 1FBZA 1LUMA 2LQWA 2ABLA 3VS7A 1AYAA 2AUGA 2KNOA 3TL0A 1R1SA 3PQZA 1O4CA 4H1OA 5AULA 5AXIA 3HCKA 3MXCA 1SHAA 1LCJA 3US4A 3OV1A 1A81A 2CIAA 1M61A 4K44A 1BFIA 1A1CA 2C0OA 2K7AB 5DC4A 1JWOA 2H8HA 3WA4A 1MILA 2DX0A 2EU0A 3M7FA 5GJHA 5KAZA 1BHFA 2IUHA 1BLJA 1O4BA 3S8NA 1O49A 1O4KA 4FBNA 4QSYA 1QG1E 1A07A 3S9KA 1D1ZA 1LUNA 5BO4A 2CI9A 1QADA 3PFVA 4X6SA 1A09A 1O48A 3PSJA 2KK6A 2EO3A 4F5BA 2ETZA 5EHPA 2MK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YSX A;  1KA7 A;  1HCT B;  3KFJ A;  1FHS A;  2Y1N A;  1AYB A;  2EYZ A;  2L6K A;  3IN8 A;  1O4P A;  5GJI A;  2C0I A;  3VS6 A;  1X27 A;  1HCS B;  3S8L A;  2ROR A;  2YU7 A;  2HDX A;  3VS2 A;  2FO0 A;  2LQN A;  2RVF A;  2Y3A B;  3N84 A;  2EO6 A;  1NZL A;  1NRV A;  2PTK A;  4P9Z A;  2IUG A;  1IJR A;  3N7Y A;  1O41 A;  2AOB A;  4A4C A;  1BHH A;  1OPK A;  3VS0 A;  1O4Q A;  3VRQ A;  3BUM B;  4F59 A;  5IBM A;  1BKL A;  4NWF A;  1Y1U A;  3VS4 A;  3PLF B;  1YVH A;  1O4J A;  5DF6 A;  1FU6 A;  4K45 A;  2DLY A;  1O43 A;  2OZO A;  4JEG A;  5HKY A;  3OB2 B;  1B47 A;  4LUD A;  1UUR A;  2DM0 A;  5CDW A;  4NWG A;  4GPL B;  3VS5 A;  4DGP A;  3MXY A;  4WWQ A;  3IN7 A;  3CD3 A;  3BUW B;  3ZNI A;  1O4N A;  1BF5 A;  2EKX A;  3PJP A;  4LUE A;  3VRR A;  5DC0 B;  1RJA A;  1AOT F;  4E93 A;  1OO4 A;  3EAZ A;  2MQI A;  3VRN A;  2LNX A;  5D0J A;  2RMX A;  3GXW A;  4FL2 A;  4M4Z A;  1MW4 A;  1GRI A;  1O4R A;  3OP0 A;  4EIH A;  1CSZ A;  5EG3 B;  2EYV A;  5EHR A;  1IS0 A;  4TZI A;  1BLK A;  3N8M A;  1AB2 A;  2LNW A;  1O4G A;  1CWE A;  2QMS A;  3OVE A;  3S8O A;  1SHB A;  2GSB A;  3PS5 A;  3VS3 A;  2MC1 A;  1YVL A;  3GQI B;  1ZFP E;  1O42 A;  3VRZ A;  3VS1 A;  5IBS A;  1X0N A;  1X6C A;  1O4I A;  1WQU A;  3BKB A;  1R1P A;  4OHI A;  4FL3 A;  3CBL A;  2L3T A;  4L1B B;  2CS0 A;  2BBU A;  2OQ1 A;  1O46 A;  3TKZ A;  4P9V A;  2MRK A;  2PLE A;  4EY0 A;  4ROJ A;  1BFJ A;  5HKZ A;  1O45 A;  1KA6 A;  1QCF A;  1I3Z A;  4E68 A;  1TZE E;  2SHP A;  2GE9 A;  3UF4 A;  2Y1M A;  4H34 A;  5J3X A;  1FYR A;  2HMH A;  1JYU A;  2CBL A;  1F2F A;  1D4W A;  2EOB A;  2EYY A;  3OB1 B;  4JGH A;  2H5K A;  1FU5 A;  1JYQ A;  1SHD A;  5I6V A;  1O4D A;  4A4B A;  3IMJ A;  2PNA A;  1O4H A;  4D8K A;  3HHM B;  3QWX X;  3GXX A;  1KC2 A;  2DLZ A;  1O4E A;  1PIC A;  3QWY A;  1P13 A;  3PSK A;  1CJ1 A;  1UUS A;  3VGO A;  4XZ1 A;  1O4F A;  2AOA A;  2XP1 A;  5EEL A;  1R1Q A;  4GL9 E;  3K2M A;  1O4L A;  1SPR A;  1LUI A;  1BG1 A;  3C7I A;  1KSW A;  1LKL A;  1O4M A;  2ECD A;  1A1A A;  1K9A A;  2DCR A;  1XA6 A;  2B3O A;  1D4T A;  2CI8 A;  3VRY A;  2SRC A;  4F5A A;  1BKM A;  3IMD A;  4DGX A;  1SPS A;  2H46 E;  1A1E A;  2CRH A;  1GHU A;  2DVJ A;  1RPY A;  2C0T A;  1OPL A;  2HCK A;  2PNB A;  1FBV A;  2FCI A;  1G83 A;  1NZV A;  4OHD A;  1FMK A;  1O44 A;  3BUO B;  1BM2 A;  2EL8 A;  1BHH B;  1CWD L;  2RSY A;  4OHE A;  3EAC A;  2L4K A;  2C9W A;  4K2R A;  4K11 A;  3MAZ A;  2IZV A;  2HDV A;  1LKK A;  3CXL A;  3VRP A;  4OHL A;  3UYO A;  1F1W A;  3BUN B;  1AOU F;  1O4A A;  2JYQ A;  3T04 A;  1LUK A;  2HUW A;  4JE4 A;  1AYD A;  1OO3 A;  1O4O A;  1A1B A;  2MRJ A;  1LCK A;  3NHN A;  3HIZ B;  2PLD A;  1JU5 A;  2IUI A;  3VRO A;  1AYC A;  1O47 A;  4XZ0 A;  4GWF A;  1H9O A;  1A08 A;  1SKJ A;  1M27 A;  3CWG A;  3BUX B;  2LCT A;  4U17 A;  2VIF A;  1JYR A;  1Y57 A;  1RQQ C;  5DC9 A;  1Z3K A;  1TCE A;  5HKW A;  1BMB A;  1AD5 A;  2K79 B;  1CSY A;  2CR4 A;  4U1P A;  4OHH A;  5EEQ A;  1FBZ A;  1LUM A;  2LQW A;  2ABL A;  3VS7 A;  1AYA A;  2AUG A;  2KNO A;  3TL0 A;  1R1S A;  3PQZ A;  1O4C A;  4H1O A;  5AUL A;  5AXI A;  3HCK A;  3MXC A;  1SHA A;  1LCJ A;  3US4 A;  3OV1 A;  1A81 A;  2CIA A;  1M61 A;  4K44 A;  1BFI A;  1A1C A;  2C0O A;  2K7A B;  5DC4 A;  1JWO A;  2H8H A;  3WA4 A;  1MIL A;  2DX0 A;  2EU0 A;  3M7F A;  5GJH A;  5KAZ A;  1BHF A;  2IUH A;  1BLJ A;  1O4B A;  3S8N A;  1O49 A;  1O4K A;  4FBN A;  4QSY A;  1QG1 E;  1A07 A;  3S9K A;  1D1Z A;  1LUN A;  5BO4 A;  2CI9 A;  1QAD A;  3PFV A;  4X6S A;  1A09 A;  1O48 A;  3PSJ A;  2KK6 A;  2EO3 A;  4F5B A;  2ETZ A;  5EHP A;  2MK2 A; 
#chains in the Genus database with same CATH topology
 2YSX A;  1KA7 A;  1HCT B;  3KFJ A;  1FHS A;  2Y1N A;  1AYB A;  2EYZ A;  2L6K A;  3IN8 A;  1O4P A;  5GJI A;  2C0I A;  3VS6 A;  1X27 A;  1HCS B;  3S8L A;  2ROR A;  2YU7 A;  2HDX A;  3VS2 A;  2FO0 A;  2LQN A;  2RVF A;  2Y3A B;  3N84 A;  2EO6 A;  1NZL A;  1NRV A;  2PTK A;  4P9Z A;  2IUG A;  1IJR A;  3N7Y A;  1O41 A;  2AOB A;  4A4C A;  1BHH A;  1OPK A;  3VS0 A;  1O4Q A;  3VRQ A;  3BUM B;  4F59 A;  5IBM A;  1BKL A;  4NWF A;  1Y1U A;  3VS4 A;  3PLF B;  1YVH A;  1O4J A;  5DF6 A;  1FU6 A;  4K45 A;  2DLY A;  1O43 A;  2OZO A;  4JEG A;  5HKY A;  3OB2 B;  1B47 A;  4LUD A;  1UUR A;  2DM0 A;  5CDW A;  4NWG A;  4GPL B;  3VS5 A;  4DGP A;  3MXY A;  4WWQ A;  3IN7 A;  3CD3 A;  3BUW B;  3ZNI A;  1O4N A;  1BF5 A;  2EKX A;  3PJP A;  4LUE A;  3VRR A;  5DC0 B;  1RJA A;  1AOT F;  4E93 A;  1OO4 A;  3EAZ A;  2MQI A;  3VRN A;  3LYV A;  2LNX A;  5D0J A;  2RMX A;  3GXW A;  4FL2 A;  4M4Z A;  1MW4 A;  1GRI A;  1O4R A;  3OP0 A;  4EIH A;  1CSZ A;  5EG3 B;  2EYV A;  5EHR A;  1IS0 A;  4TZI A;  1BLK A;  3N8M A;  1AB2 A;  2LNW A;  1O4G A;  1CWE A;  2QMS A;  3OVE A;  3S8O A;  1SHB A;  2GSB A;  3PS5 A;  3VS3 A;  2MC1 A;  1YVL A;  3GQI B;  1ZFP E;  1O42 A;  3VRZ A;  3VS1 A;  5IBS A;  1X0N A;  1X6C A;  1O4I A;  1WQU A;  3BKB A;  1R1P A;  4OHI A;  4FL3 A;  3CBL A;  2L3T A;  4L1B B;  2CS0 A;  2BBU A;  2OQ1 A;  1O46 A;  3TKZ A;  4P9V A;  2MRK A;  2PLE A;  4EY0 A;  4ROJ A;  1BFJ A;  5HKZ A;  1O45 A;  1KA6 A;  1QCF A;  1I3Z A;  4E68 A;  1TZE E;  2SHP A;  2GE9 A;  3UF4 A;  2Y1M A;  4H34 A;  5J3X A;  1FYR A;  2HMH A;  1JYU A;  2CBL A;  1F2F A;  1D4W A;  2EOB A;  2EYY A;  3OB1 B;  4JGH A;  2H5K A;  1FU5 A;  1JYQ A;  1SHD A;  5I6V A;  1O4D A;  4A4B A;  2LRA A;  2PNA A;  1O4H A;  3IMJ A;  4D8K A;  3HHM B;  3QWX X;  3GXX A;  1KC2 A;  2DLZ A;  1O4E A;  1PIC A;  3QWY A;  1P13 A;  3PSK A;  1CJ1 A;  1UUS A;  3VGO A;  4XZ1 A;  1O4F A;  2AOA A;  2XP1 A;  5EEL A;  1R1Q A;  4GL9 E;  3K2M A;  1O4L A;  1SPR A;  1LUI A;  1BG1 A;  3C7I A;  1KSW A;  1LKL A;  1O4M A;  2ECD A;  1A1A A;  1K9A A;  2DCR A;  1XA6 A;  2B3O A;  1D4T A;  2CI8 A;  3VRY A;  2SRC A;  4F5A A;  1BKM A;  3IMD A;  4DGX A;  1SPS A;  2H46 E;  1A1E A;  2CRH A;  1GHU A;  2DVJ A;  1RPY A;  2C0T A;  1OPL A;  2HCK A;  2PNB A;  1FBV A;  2FCI A;  1G83 A;  1NZV A;  4OHD A;  1FMK A;  1O44 A;  3BUO B;  1BM2 A;  2EL8 A;  1BHH B;  1CWD L;  2RSY A;  4OHE A;  3EAC A;  2L4K A;  2C9W A;  4K2R A;  4K11 A;  3MAZ A;  2IZV A;  2HDV A;  1LKK A;  3CXL A;  3VRP A;  3K2T A;  4OHL A;  3UYO A;  1F1W A;  3BUN B;  1AOU F;  1O4A A;  2JYQ A;  3T04 A;  1LUK A;  2HUW A;  4JE4 A;  1AYD A;  1OO3 A;  1O4O A;  1A1B A;  2MRJ A;  1LCK A;  3NHN A;  3HIZ B;  2PLD A;  1JU5 A;  2IUI A;  3VRO A;  1AYC A;  2KGY A;  1O47 A;  4XZ0 A;  4GWF A;  1H9O A;  1A08 A;  1SKJ A;  1M27 A;  3CWG A;  3BUX B;  2LCT A;  4U17 A;  2VIF A;  1JYR A;  1Y57 A;  1RQQ C;  5DC9 A;  1Z3K A;  1TCE A;  5HKW A;  1BMB A;  1AD5 A;  2K79 B;  1CSY A;  2CR4 A;  4U1P A;  4OHH A;  5EEQ A;  1FBZ A;  1LUM A;  2LQW A;  2ABL A;  3VS7 A;  1AYA A;  2AUG A;  2KNO A;  3TL0 A;  1R1S A;  3PQZ A;  1O4C A;  4H1O A;  5AUL A;  5AXI A;  3HCK A;  3MXC A;  1SHA A;  1LCJ A;  3US4 A;  3OV1 A;  1A81 A;  2CIA A;  1M61 A;  4K44 A;  1BFI A;  1A1C A;  2C0O A;  2K7A B;  5DC4 A;  1JWO A;  2H8H A;  3WA4 A;  1MIL A;  2DX0 A;  2EU0 A;  3M7F A;  5GJH A;  5KAZ A;  1BHF A;  2IUH A;  1BLJ A;  1O4B A;  3S8N A;  1O49 A;  1O4K A;  4FBN A;  4QSY A;  1QG1 E;  1A07 A;  3S9K A;  1D1Z A;  1LUN A;  5BO4 A;  2CI9 A;  1QAD A;  3PFV A;  4X6S A;  1A09 A;  1O48 A;  3PSJ A;  2KK6 A;  2EO3 A;  4F5B A;  2ETZ A;  5EHP A;  2MK2 A; 
#chains in the Genus database with same CATH homology
 2YSX A;  1KA7 A;  1HCT B;  3KFJ A;  1FHS A;  2Y1N A;  1AYB A;  2EYZ A;  2L6K A;  3IN8 A;  1O4P A;  5GJI A;  2C0I A;  3VS6 A;  1X27 A;  1HCS B;  3S8L A;  2ROR A;  2YU7 A;  2HDX A;  3VS2 A;  2FO0 A;  2LQN A;  2RVF A;  2Y3A B;  3N84 A;  2EO6 A;  1NZL A;  1NRV A;  2PTK A;  4P9Z A;  2IUG A;  1IJR A;  3N7Y A;  1O41 A;  2AOB A;  4A4C A;  1BHH A;  1OPK A;  3VS0 A;  1O4Q A;  3VRQ A;  3BUM B;  4F59 A;  5IBM A;  1BKL A;  4NWF A;  1Y1U A;  3VS4 A;  3PLF B;  1YVH A;  1O4J A;  5DF6 A;  1FU6 A;  4K45 A;  2DLY A;  1O43 A;  2OZO A;  4JEG A;  5HKY A;  3OB2 B;  1B47 A;  4LUD A;  1UUR A;  2DM0 A;  5CDW A;  4NWG A;  4GPL B;  3VS5 A;  4DGP A;  3MXY A;  4WWQ A;  3IN7 A;  3CD3 A;  3BUW B;  3ZNI A;  1O4N A;  1BF5 A;  2EKX A;  3PJP A;  4LUE A;  3VRR A;  5DC0 B;  1RJA A;  1AOT F;  4E93 A;  1OO4 A;  3EAZ A;  2MQI A;  3VRN A;  2LNX A;  5D0J A;  2RMX A;  3GXW A;  4FL2 A;  4M4Z A;  1MW4 A;  1GRI A;  1O4R A;  3OP0 A;  4EIH A;  1CSZ A;  5EG3 B;  2EYV A;  5EHR A;  1IS0 A;  4TZI A;  1BLK A;  3N8M A;  1AB2 A;  2LNW A;  1O4G A;  1CWE A;  2QMS A;  3OVE A;  3S8O A;  1SHB A;  2GSB A;  3PS5 A;  3VS3 A;  2MC1 A;  1YVL A;  3GQI B;  1ZFP E;  1O42 A;  3VRZ A;  3VS1 A;  5IBS A;  1X0N A;  1X6C A;  1O4I A;  1WQU A;  3BKB A;  1R1P A;  4OHI A;  4FL3 A;  3CBL A;  2L3T A;  4L1B B;  2CS0 A;  2BBU A;  2OQ1 A;  1O46 A;  3TKZ A;  4P9V A;  2MRK A;  2PLE A;  4EY0 A;  4ROJ A;  1BFJ A;  5HKZ A;  1O45 A;  1KA6 A;  1QCF A;  1I3Z A;  4E68 A;  1TZE E;  2SHP A;  2GE9 A;  3UF4 A;  2Y1M A;  4H34 A;  5J3X A;  1FYR A;  2HMH A;  1JYU A;  2CBL A;  1F2F A;  1D4W A;  2EOB A;  2EYY A;  3OB1 B;  4JGH A;  2H5K A;  1FU5 A;  1JYQ A;  1SHD A;  5I6V A;  1O4D A;  4A4B A;  3IMJ A;  2PNA A;  1O4H A;  4D8K A;  3HHM B;  3QWX X;  3GXX A;  1KC2 A;  2DLZ A;  1O4E A;  1PIC A;  3QWY A;  1P13 A;  3PSK A;  1CJ1 A;  1UUS A;  3VGO A;  4XZ1 A;  1O4F A;  2AOA A;  2XP1 A;  5EEL A;  1R1Q A;  4GL9 E;  3K2M A;  1O4L A;  1SPR A;  1LUI A;  1BG1 A;  3C7I A;  1KSW A;  1LKL A;  1O4M A;  2ECD A;  1A1A A;  1K9A A;  2DCR A;  1XA6 A;  2B3O A;  1D4T A;  2CI8 A;  3VRY A;  2SRC A;  4F5A A;  1BKM A;  3IMD A;  4DGX A;  1SPS A;  2H46 E;  1A1E A;  2CRH A;  1GHU A;  2DVJ A;  1RPY A;  2C0T A;  1OPL A;  2HCK A;  2PNB A;  1FBV A;  2FCI A;  1G83 A;  1NZV A;  4OHD A;  1FMK A;  1O44 A;  3BUO B;  1BM2 A;  2EL8 A;  1BHH B;  1CWD L;  2RSY A;  4OHE A;  3EAC A;  2L4K A;  2C9W A;  4K2R A;  4K11 A;  3MAZ A;  2IZV A;  2HDV A;  1LKK A;  3CXL A;  3VRP A;  4OHL A;  3UYO A;  1F1W A;  3BUN B;  1AOU F;  1O4A A;  2JYQ A;  3T04 A;  1LUK A;  2HUW A;  4JE4 A;  1AYD A;  1OO3 A;  1O4O A;  1A1B A;  2MRJ A;  1LCK A;  3NHN A;  3HIZ B;  2PLD A;  1JU5 A;  2IUI A;  3VRO A;  1AYC A;  1O47 A;  4XZ0 A;  4GWF A;  1H9O A;  1A08 A;  1SKJ A;  1M27 A;  3CWG A;  3BUX B;  2LCT A;  4U17 A;  2VIF A;  1JYR A;  1Y57 A;  1RQQ C;  5DC9 A;  1Z3K A;  1TCE A;  5HKW A;  1BMB A;  1AD5 A;  2K79 B;  1CSY A;  2CR4 A;  4U1P A;  4OHH A;  5EEQ A;  1FBZ A;  1LUM A;  2LQW A;  2ABL A;  3VS7 A;  1AYA A;  2AUG A;  2KNO A;  3TL0 A;  1R1S A;  3PQZ A;  1O4C A;  4H1O A;  5AUL A;  5AXI A;  3HCK A;  3MXC A;  1SHA A;  1LCJ A;  3US4 A;  3OV1 A;  1A81 A;  2CIA A;  1M61 A;  4K44 A;  1BFI A;  1A1C A;  2C0O A;  2K7A B;  5DC4 A;  1JWO A;  2H8H A;  3WA4 A;  1MIL A;  2DX0 A;  2EU0 A;  3M7F A;  5GJH A;  5KAZ A;  1BHF A;  2IUH A;  1BLJ A;  1O4B A;  3S8N A;  1O49 A;  1O4K A;  4FBN A;  4QSY A;  1QG1 E;  1A07 A;  3S9K A;  1D1Z A;  1LUN A;  5BO4 A;  2CI9 A;  1QAD A;  3PFV A;  4X6S A;  1A09 A;  1O48 A;  3PSJ A;  2KK6 A;  2EO3 A;  4F5B A;  2ETZ A;  5EHP A;  2MK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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