1O4RA

Crystal structure of sh2 in complex with ru78783.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
105
structure length
105
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 27
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o4rA00
1D4WA 3T04A 3VS5A 1HCTB 2VIFA 5AXIA 1O43A 3QWYA 1R1SA 4EIHA 2LNWA 1NZVA 1JYRA 2C9WA 1LCKA 4NWGA 3IN8A 3EACA 1PICA 3PSJA 1O4BA 1I3ZA 2MK2A 2DVJA 1SHAA 1BHHB 2EYZA 2MRKA 3PS5A 5I6VA 3N8MA 5AULA 4GPLB 3VRZA 4K44A 2L4KA 1FHSA 4U17A 4OHHA 4E68A 2L6KA 2RMXA 1UURA 1BHHA 4OHDA 2HUWA 3PJPA 1O4MA 2EO3A 2HDXA 1A08A 3GXXA 4K45A 5J3XA 5DF6A 2EYVA 5HKWA 3VS4A 3BKBA 1BMBA 3OB1B 2DCRA 2FO0A 1D1ZA 3VRYA 3IMJA 4XZ1A 2EO6A 3MAZA 1O49A 4U1PA 2JYQA 2IUGA 3VS3A 1SHBA 2AUGA 2YU7A 3TKZA 1D4TA 3OVEA 2DX0A 4F5BA 2RORA 2YSXA 2IUHA 2CRHA 5HKZA 1TCEA 4E93A 1O4CA 4GWFA 1BLJA 1O4EA 1O4QA 4JEGA 2LQNA 1FBVA 4OHEA 2C0OA 1A07A 3PSKA 4ROJA 3IMDA 4L1BB 5EHRA 2PNAA 3VRRA 4FL2A 2H5KA 2CI8A 3CD3A 3KFJA 3VRQA 4K11A 3CWGA 4OHLA 3PQZA 1BKMA 1JYQA 1ZFPE 2RVFA 2GSBA 5EEQA 1AYDA 3VRNA 2PLDA 1FBZA 1M61A 4X6SA 2AOAA 1Y57A 1KC2A 3UYOA 3CXLA 2EU0A 1R1QA 1X0NA 1O4AA 1RPYA 1F1WA 3BUXB 2H46E 1QCFA 3OB2B 1A81A 3QWXX 1A1BA 4FL3A 5EHPA 5DC0B 1NZLA 2KK6A 2EKXA 1R1PA 3VGOA 3EAZA 2B3OA 1WQUA 5IBSA 4P9VA 1O44A 2CR4A 3HIZB 1LKLA 1CSYA 1YVLA 3VS0A 2EL8A 2LCTA 1KSWA 1O46A 1H9OA 3NHNA 2LNXA 1AYCA 1RJAA 3BUOB 1YVHA 4A4BA 1X6CA 1HCSB 1KA6A 2GE9A 1LUMA 3US4A 1O4HA 3N7YA 1O4GA 5BO4A 1CWEA 1XA6A 3BUWB 3VS6A 1BG1A 1P13A 1O4FA 5DC9A 3GQIB 1AYAA 1AB2A 2K79B 2RSYA 3S8OA 1BHFA 1SPRA 3VROA 2DLZA 1BFJA 5IBMA 2QMSA 2C0IA 4NWFA 4F59A 2ABLA 2BBUA 2XP1A 1B47A 2CI9A 5CDWA 2CBLA 1BKLA 2H8HA 2L3TA 1BFIA 1Z3KA 2IZVA 1SPSA 1BF5A 3GXWA 4WWQA 4K2RA 3OP0A 4EY0A 2CIAA 1O45A 1F2FA 1OO3A 5DC4A 1LUKA 1JWOA 2DLYA 2OZOA 4TZIA 1FYRA 1CWDL 2K7AB 2CS0A 2Y1MA 3HHMB 3PLFB 5EELA 2FCIA 1O4OA 1LCJA 2SHPA 3MXCA 2EOBA 1FMKA 1A09A 2ECDA 1Y1UA 2Y3AB 1A1CA 1A1AA 1SKJA 1AOTF 4H34A 1O4LA 1JU5A 4DGXA 4LUDA 3IN7A 3VS2A 1AYBA 3S8NA 1O48A 2LQWA 3N84A 5EG3B 1O42A 1M27A 1RQQC 4M4ZA 3M7FA 1BLKA 1O4DA 1FU6A 1LUNA 4QSYA 1IS0A 2MRJA 2EYYA 1OPLA 1LKKA 2ETZA 4FBNA 1X27A 3VS7A 1AD5A 1O41A 2Y1NA 4GL9E 1K9AA 2PNBA 4A4CA 1QG1E 4XZ0A 3S8LA 1LUIA 5D0JA 2HCKA 4OHIA 3MXYA 5GJHA 1OO4A 2OQ1A 4DGPA 4JGHA 1CSZA 1O4IA 1O4KA 2PTKA 1BM2A 1QADA 3S9KA 2HMHA 4JE4A 1TZEE 3WA4A 1A1EA 2PLEA 1AOUF 4P9ZA 3BUMB 1MW4A 1IJRA 4F5AA 1GRIA 3ZNIA 2MC1A 1O4RA 1UUSA 3VS1A 1NRVA 1MILA 2HDVA 3UF4A 1G83A 1O4NA 2IUIA 1SHDA 3BUNB 1FU5A 5KAZA 3OV1A 1O4JA 4LUEA 3HCKA 3VRPA 2KNOA 2SRCA 1CJ1A 1JYUA 4D8KA 3TL0A 1O4PA 2C0TA 4H1OA 3CBLA 3PFVA 5GJIA 1GHUA 2AOBA 3K2MA 2MQIA 1O47A 1OPKA 5HKYA 3C7IA 1KA7A 2DM0A
chains in the Genus database with same CATH superfamily
1D4WA 3T04A 3VS5A 1HCTB 2VIFA 5AXIA 1O43A 3QWYA 1R1SA 4EIHA 2LNWA 1NZVA 1JYRA 2C9WA 1LCKA 4NWGA 3IN8A 3EACA 1PICA 3PSJA 1O4BA 1I3ZA 2MK2A 2DVJA 1SHAA 1BHHB 2EYZA 2MRKA 3PS5A 5I6VA 3N8MA 5AULA 4GPLB 3VRZA 4K44A 2L4KA 1FHSA 4U17A 4OHHA 4E68A 2L6KA 2RMXA 1UURA 1BHHA 4OHDA 2HUWA 3PJPA 1O4MA 2EO3A 2HDXA 1A08A 3GXXA 4K45A 5J3XA 5DF6A 2EYVA 5HKWA 3VS4A 3BKBA 1BMBA 3LYVA 3OB1B 2DCRA 2FO0A 1D1ZA 3VRYA 3IMJA 4XZ1A 2EO6A 3MAZA 1O49A 4U1PA 3K2TA 2JYQA 2IUGA 3VS3A 1SHBA 2AUGA 2YU7A 3TKZA 1D4TA 3OVEA 2DX0A 4F5BA 2RORA 2YSXA 2IUHA 2CRHA 5HKZA 1TCEA 4E93A 1O4CA 4GWFA 1BLJA 1O4EA 1O4QA 4JEGA 2LQNA 1FBVA 4OHEA 2C0OA 1A07A 3PSKA 4ROJA 3IMDA 4L1BB 5EHRA 2PNAA 3VRRA 4FL2A 2H5KA 2CI8A 3CD3A 3KFJA 3VRQA 4K11A 3CWGA 4OHLA 3PQZA 1BKMA 1JYQA 1ZFPE 2RVFA 2GSBA 5EEQA 1AYDA 3VRNA 2PLDA 2LRAA 1FBZA 1M61A 4X6SA 2AOAA 1Y57A 1KC2A 3UYOA 3CXLA 2EU0A 1R1QA 1X0NA 1O4AA 1RPYA 1F1WA 3BUXB 2H46E 1QCFA 3OB2B 1A81A 3QWXX 1A1BA 4FL3A 5EHPA 5DC0B 1NZLA 2KK6A 2EKXA 1R1PA 3VGOA 3EAZA 2B3OA 1WQUA 5IBSA 4P9VA 1O44A 2CR4A 3HIZB 1LKLA 1CSYA 1YVLA 3VS0A 2EL8A 2LCTA 1KSWA 1O46A 1H9OA 3NHNA 2LNXA 1AYCA 1RJAA 3BUOB 1YVHA 4A4BA 1X6CA 1HCSB 1KA6A 2GE9A 1LUMA 3US4A 1O4HA 3N7YA 1O4GA 5BO4A 1CWEA 1XA6A 3BUWB 3VS6A 1BG1A 1P13A 1O4FA 5DC9A 3GQIB 1AYAA 1AB2A 2K79B 2RSYA 3S8OA 1BHFA 1SPRA 3VROA 2DLZA 1BFJA 5IBMA 2QMSA 2C0IA 4NWFA 4F59A 2ABLA 2BBUA 2XP1A 1B47A 2CI9A 5CDWA 2CBLA 1BKLA 2H8HA 2L3TA 1BFIA 1Z3KA 2IZVA 1SPSA 1BF5A 3GXWA 4WWQA 4K2RA 3OP0A 4EY0A 2CIAA 2KGYA 1O45A 1F2FA 1OO3A 5DC4A 1LUKA 1JWOA 2DLYA 2OZOA 4TZIA 1FYRA 1CWDL 2K7AB 2CS0A 2Y1MA 3HHMB 3PLFB 5EELA 2FCIA 1O4OA 1LCJA 2SHPA 3MXCA 2EOBA 1FMKA 1A09A 2ECDA 1Y1UA 2Y3AB 1A1CA 1A1AA 1SKJA 1AOTF 4H34A 1O4LA 1JU5A 4DGXA 4LUDA 3IN7A 3VS2A 1AYBA 3S8NA 1O48A 2LQWA 3N84A 5EG3B 1O42A 1M27A 1RQQC 4M4ZA 3M7FA 1BLKA 1O4DA 1FU6A 1LUNA 4QSYA 1IS0A 2MRJA 2EYYA 1OPLA 1LKKA 2ETZA 4FBNA 1X27A 3VS7A 1AD5A 1O41A 2Y1NA 4GL9E 1K9AA 2PNBA 4A4CA 1QG1E 4XZ0A 3S8LA 1LUIA 5D0JA 2HCKA 4OHIA 3MXYA 5GJHA 1OO4A 2OQ1A 4DGPA 4JGHA 1CSZA 1O4IA 1O4KA 2PTKA 1BM2A 1QADA 3S9KA 2HMHA 4JE4A 1TZEE 3WA4A 1A1EA 2PLEA 1AOUF 4P9ZA 3BUMB 1MW4A 1IJRA 4F5AA 1GRIA 3ZNIA 2MC1A 1O4RA 1UUSA 3VS1A 1NRVA 1MILA 2HDVA 3UF4A 1G83A 1O4NA 2IUIA 1SHDA 3BUNB 1FU5A 5KAZA 3OV1A 1O4JA 4LUEA 3HCKA 3VRPA 2KNOA 2SRCA 1CJ1A 1JYUA 4D8KA 3TL0A 1O4PA 2C0TA 4H1OA 3CBLA 3PFVA 5GJIA 1GHUA 2AOBA 3K2MA 2MQIA 1O47A 1OPKA 5HKYA 3C7IA 1KA7A 2DM0A
chains in the Genus database with same CATH topology
1D4WA 3T04A 3VS5A 1HCTB 2VIFA 5AXIA 1O43A 3QWYA 1R1SA 4EIHA 2LNWA 1NZVA 1JYRA 2C9WA 1LCKA 4NWGA 3IN8A 3EACA 1PICA 3PSJA 1O4BA 1I3ZA 2MK2A 2DVJA 1SHAA 1BHHB 2EYZA 2MRKA 3PS5A 5I6VA 3N8MA 5AULA 4GPLB 3VRZA 4K44A 2L4KA 1FHSA 4U17A 4OHHA 4E68A 2L6KA 2RMXA 1UURA 1BHHA 4OHDA 2HUWA 3PJPA 1O4MA 2EO3A 2HDXA 1A08A 3GXXA 4K45A 5J3XA 5DF6A 2EYVA 5HKWA 3VS4A 3BKBA 1BMBA 3OB1B 2DCRA 2FO0A 1D1ZA 3VRYA 3IMJA 4XZ1A 2EO6A 3MAZA 1O49A 4U1PA 2JYQA 2IUGA 3VS3A 1SHBA 2AUGA 2YU7A 3TKZA 1D4TA 3OVEA 2DX0A 4F5BA 2RORA 2YSXA 2IUHA 2CRHA 5HKZA 1TCEA 4E93A 1O4CA 4GWFA 1BLJA 1O4EA 1O4QA 4JEGA 2LQNA 1FBVA 4OHEA 2C0OA 1A07A 3PSKA 4ROJA 3IMDA 4L1BB 5EHRA 2PNAA 3VRRA 4FL2A 2H5KA 2CI8A 3CD3A 3KFJA 3VRQA 4K11A 3CWGA 4OHLA 3PQZA 1BKMA 1JYQA 1ZFPE 2RVFA 2GSBA 5EEQA 1AYDA 3VRNA 2PLDA 1FBZA 1M61A 4X6SA 2AOAA 1Y57A 1KC2A 3UYOA 3CXLA 2EU0A 1R1QA 1X0NA 1O4AA 1RPYA 1F1WA 3BUXB 2H46E 1QCFA 3OB2B 1A81A 3QWXX 1A1BA 4FL3A 5EHPA 5DC0B 1NZLA 2KK6A 2EKXA 1R1PA 3VGOA 3EAZA 2B3OA 1WQUA 5IBSA 4P9VA 1O44A 2CR4A 3HIZB 1LKLA 1CSYA 1YVLA 3VS0A 2EL8A 2LCTA 1KSWA 1O46A 1H9OA 3NHNA 2LNXA 1AYCA 1RJAA 3BUOB 1YVHA 4A4BA 1X6CA 1HCSB 1KA6A 2GE9A 1LUMA 3US4A 1O4HA 3N7YA 1O4GA 5BO4A 1CWEA 1XA6A 3BUWB 3VS6A 1BG1A 1P13A 1O4FA 5DC9A 3GQIB 1AYAA 1AB2A 2K79B 2RSYA 3S8OA 1BHFA 1SPRA 3VROA 2DLZA 1BFJA 5IBMA 2QMSA 2C0IA 4NWFA 4F59A 2ABLA 2BBUA 2XP1A 1B47A 2CI9A 5CDWA 2CBLA 1BKLA 2H8HA 2L3TA 1BFIA 1Z3KA 2IZVA 1SPSA 1BF5A 3GXWA 4WWQA 4K2RA 3OP0A 4EY0A 2CIAA 1O45A 1F2FA 1OO3A 5DC4A 1LUKA 1JWOA 2DLYA 2OZOA 4TZIA 1FYRA 1CWDL 2K7AB 2CS0A 2Y1MA 3HHMB 3PLFB 5EELA 2FCIA 1O4OA 1LCJA 2SHPA 3MXCA 2EOBA 1FMKA 1A09A 2ECDA 1Y1UA 2Y3AB 1A1CA 1A1AA 1SKJA 1AOTF 4H34A 1O4LA 1JU5A 4DGXA 4LUDA 3IN7A 3VS2A 1AYBA 3S8NA 1O48A 2LQWA 3N84A 5EG3B 1O42A 1M27A 1RQQC 4M4ZA 3M7FA 1BLKA 1O4DA 1FU6A 1LUNA 4QSYA 1IS0A 2MRJA 2EYYA 1OPLA 1LKKA 2ETZA 4FBNA 1X27A 3VS7A 1AD5A 1O41A 2Y1NA 4GL9E 1K9AA 2PNBA 4A4CA 1QG1E 4XZ0A 3S8LA 1LUIA 5D0JA 2HCKA 4OHIA 3MXYA 5GJHA 1OO4A 2OQ1A 4DGPA 4JGHA 1CSZA 1O4IA 1O4KA 2PTKA 1BM2A 1QADA 3S9KA 2HMHA 4JE4A 1TZEE 3WA4A 1A1EA 2PLEA 1AOUF 4P9ZA 3BUMB 1MW4A 1IJRA 4F5AA 1GRIA 3ZNIA 2MC1A 1O4RA 1UUSA 3VS1A 1NRVA 1MILA 2HDVA 3UF4A 1G83A 1O4NA 2IUIA 1SHDA 3BUNB 1FU5A 5KAZA 3OV1A 1O4JA 4LUEA 3HCKA 3VRPA 2KNOA 2SRCA 1CJ1A 1JYUA 4D8KA 3TL0A 1O4PA 2C0TA 4H1OA 3CBLA 3PFVA 5GJIA 1GHUA 2AOBA 3K2MA 2MQIA 1O47A 1OPKA 5HKYA 3C7IA 1KA7A 2DM0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D4W A;  3T04 A;  3VS5 A;  1HCT B;  2VIF A;  5AXI A;  1O43 A;  3QWY A;  1R1S A;  4EIH A;  2LNW A;  1NZV A;  1JYR A;  2C9W A;  1LCK A;  4NWG A;  3IN8 A;  3EAC A;  1PIC A;  3PSJ A;  1O4B A;  1I3Z A;  2MK2 A;  2DVJ A;  1SHA A;  1BHH B;  2EYZ A;  2MRK A;  3PS5 A;  5I6V A;  3N8M A;  5AUL A;  4GPL B;  3VRZ A;  4K44 A;  2L4K A;  1FHS A;  4U17 A;  4OHH A;  4E68 A;  2L6K A;  2RMX A;  1UUR A;  1BHH A;  4OHD A;  2HUW A;  3PJP A;  1O4M A;  2EO3 A;  2HDX A;  1A08 A;  3GXX A;  4K45 A;  5J3X A;  5DF6 A;  2EYV A;  5HKW A;  3VS4 A;  3BKB A;  1BMB A;  3OB1 B;  2DCR A;  2FO0 A;  1D1Z A;  3VRY A;  3IMJ A;  4XZ1 A;  2EO6 A;  3MAZ A;  1O49 A;  4U1P A;  2JYQ A;  2IUG A;  3VS3 A;  1SHB A;  2AUG A;  2YU7 A;  3TKZ A;  1D4T A;  3OVE A;  2DX0 A;  4F5B A;  2ROR A;  2YSX A;  2IUH A;  2CRH A;  5HKZ A;  1TCE A;  4E93 A;  1O4C A;  4GWF A;  1BLJ A;  1O4E A;  1O4Q A;  4JEG A;  2LQN A;  1FBV A;  4OHE A;  2C0O A;  1A07 A;  3PSK A;  4ROJ A;  3IMD A;  4L1B B;  5EHR A;  2PNA A;  3VRR A;  4FL2 A;  2H5K A;  2CI8 A;  3CD3 A;  3KFJ A;  3VRQ A;  4K11 A;  3CWG A;  4OHL A;  3PQZ A;  1BKM A;  1JYQ A;  1ZFP E;  2RVF A;  2GSB A;  5EEQ A;  1AYD A;  3VRN A;  2PLD A;  1FBZ A;  1M61 A;  4X6S A;  2AOA A;  1Y57 A;  1KC2 A;  3UYO A;  3CXL A;  2EU0 A;  1R1Q A;  1X0N A;  1O4A A;  1RPY A;  1F1W A;  3BUX B;  2H46 E;  1QCF A;  3OB2 B;  1A81 A;  3QWX X;  1A1B A;  4FL3 A;  5EHP A;  5DC0 B;  1NZL A;  2KK6 A;  2EKX A;  1R1P A;  3VGO A;  3EAZ A;  2B3O A;  1WQU A;  5IBS A;  4P9V A;  1O44 A;  2CR4 A;  3HIZ B;  1LKL A;  1CSY A;  1YVL A;  3VS0 A;  2EL8 A;  2LCT A;  1KSW A;  1O46 A;  1H9O A;  3NHN A;  2LNX A;  1AYC A;  1RJA A;  3BUO B;  1YVH A;  4A4B A;  1X6C A;  1HCS B;  1KA6 A;  2GE9 A;  1LUM A;  3US4 A;  1O4H A;  3N7Y A;  1O4G A;  5BO4 A;  1CWE A;  1XA6 A;  3BUW B;  3VS6 A;  1BG1 A;  1P13 A;  1O4F A;  5DC9 A;  3GQI B;  1AYA A;  1AB2 A;  2K79 B;  2RSY A;  3S8O A;  1BHF A;  1SPR A;  3VRO A;  2DLZ A;  1BFJ A;  5IBM A;  2QMS A;  2C0I A;  4NWF A;  4F59 A;  2ABL A;  2BBU A;  2XP1 A;  1B47 A;  2CI9 A;  5CDW A;  2CBL A;  1BKL A;  2H8H A;  2L3T A;  1BFI A;  1Z3K A;  2IZV A;  1SPS A;  1BF5 A;  3GXW A;  4WWQ A;  4K2R A;  3OP0 A;  4EY0 A;  2CIA A;  1O45 A;  1F2F A;  1OO3 A;  5DC4 A;  1LUK A;  1JWO A;  2DLY A;  2OZO A;  4TZI A;  1FYR A;  1CWD L;  2K7A B;  2CS0 A;  2Y1M A;  3HHM B;  3PLF B;  5EEL A;  2FCI A;  1O4O A;  1LCJ A;  2SHP A;  3MXC A;  2EOB A;  1FMK A;  1A09 A;  2ECD A;  1Y1U A;  2Y3A B;  1A1C A;  1A1A A;  1SKJ A;  1AOT F;  4H34 A;  1O4L A;  1JU5 A;  4DGX A;  4LUD A;  3IN7 A;  3VS2 A;  1AYB A;  3S8N A;  1O48 A;  2LQW A;  3N84 A;  5EG3 B;  1O42 A;  1M27 A;  1RQQ C;  4M4Z A;  3M7F A;  1BLK A;  1O4D A;  1FU6 A;  1LUN A;  4QSY A;  1IS0 A;  2MRJ A;  2EYY A;  1OPL A;  1LKK A;  2ETZ A;  4FBN A;  1X27 A;  3VS7 A;  1AD5 A;  1O41 A;  2Y1N A;  4GL9 E;  1K9A A;  2PNB A;  4A4C A;  1QG1 E;  4XZ0 A;  3S8L A;  1LUI A;  5D0J A;  2HCK A;  4OHI A;  3MXY A;  5GJH A;  1OO4 A;  2OQ1 A;  4DGP A;  4JGH A;  1CSZ A;  1O4I A;  1O4K A;  2PTK A;  1BM2 A;  1QAD A;  3S9K A;  2HMH A;  4JE4 A;  1TZE E;  3WA4 A;  1A1E A;  2PLE A;  1AOU F;  4P9Z A;  3BUM B;  1MW4 A;  1IJR A;  4F5A A;  1GRI A;  3ZNI A;  2MC1 A;  1O4R A;  1UUS A;  3VS1 A;  1NRV A;  1MIL A;  2HDV A;  3UF4 A;  1G83 A;  1O4N A;  2IUI A;  1SHD A;  3BUN B;  1FU5 A;  5KAZ A;  3OV1 A;  1O4J A;  4LUE A;  3HCK A;  3VRP A;  2KNO A;  2SRC A;  1CJ1 A;  1JYU A;  4D8K A;  3TL0 A;  1O4P A;  2C0T A;  4H1O A;  3CBL A;  3PFV A;  5GJI A;  1GHU A;  2AOB A;  3K2M A;  2MQI A;  1O47 A;  1OPK A;  5HKY A;  3C7I A;  1KA7 A;  2DM0 A; 
#chains in the Genus database with same CATH topology
 1D4W A;  3T04 A;  3VS5 A;  1HCT B;  2VIF A;  5AXI A;  1O43 A;  3QWY A;  1R1S A;  4EIH A;  2LNW A;  1NZV A;  1JYR A;  2C9W A;  1LCK A;  4NWG A;  3IN8 A;  3EAC A;  1PIC A;  3PSJ A;  1O4B A;  1I3Z A;  2MK2 A;  2DVJ A;  1SHA A;  1BHH B;  2EYZ A;  2MRK A;  3PS5 A;  5I6V A;  3N8M A;  5AUL A;  4GPL B;  3VRZ A;  4K44 A;  2L4K A;  1FHS A;  4U17 A;  4OHH A;  4E68 A;  2L6K A;  2RMX A;  1UUR A;  1BHH A;  4OHD A;  2HUW A;  3PJP A;  1O4M A;  2EO3 A;  2HDX A;  1A08 A;  3GXX A;  4K45 A;  5J3X A;  5DF6 A;  2EYV A;  5HKW A;  3VS4 A;  3BKB A;  1BMB A;  3LYV A;  3OB1 B;  2DCR A;  2FO0 A;  1D1Z A;  3VRY A;  3IMJ A;  4XZ1 A;  2EO6 A;  3MAZ A;  1O49 A;  4U1P A;  3K2T A;  2JYQ A;  2IUG A;  3VS3 A;  1SHB A;  2AUG A;  2YU7 A;  3TKZ A;  1D4T A;  3OVE A;  2DX0 A;  4F5B A;  2ROR A;  2YSX A;  2IUH A;  2CRH A;  5HKZ A;  1TCE A;  4E93 A;  1O4C A;  4GWF A;  1BLJ A;  1O4E A;  1O4Q A;  4JEG A;  2LQN A;  1FBV A;  4OHE A;  2C0O A;  1A07 A;  3PSK A;  4ROJ A;  3IMD A;  4L1B B;  5EHR A;  2PNA A;  3VRR A;  4FL2 A;  2H5K A;  2CI8 A;  3CD3 A;  3KFJ A;  3VRQ A;  4K11 A;  3CWG A;  4OHL A;  3PQZ A;  1BKM A;  1JYQ A;  1ZFP E;  2RVF A;  2GSB A;  5EEQ A;  1AYD A;  3VRN A;  2PLD A;  2LRA A;  1FBZ A;  1M61 A;  4X6S A;  2AOA A;  1Y57 A;  1KC2 A;  3UYO A;  3CXL A;  2EU0 A;  1R1Q A;  1X0N A;  1O4A A;  1RPY A;  1F1W A;  3BUX B;  2H46 E;  1QCF A;  3OB2 B;  1A81 A;  3QWX X;  1A1B A;  4FL3 A;  5EHP A;  5DC0 B;  1NZL A;  2KK6 A;  2EKX A;  1R1P A;  3VGO A;  3EAZ A;  2B3O A;  1WQU A;  5IBS A;  4P9V A;  1O44 A;  2CR4 A;  3HIZ B;  1LKL A;  1CSY A;  1YVL A;  3VS0 A;  2EL8 A;  2LCT A;  1KSW A;  1O46 A;  1H9O A;  3NHN A;  2LNX A;  1AYC A;  1RJA A;  3BUO B;  1YVH A;  4A4B A;  1X6C A;  1HCS B;  1KA6 A;  2GE9 A;  1LUM A;  3US4 A;  1O4H A;  3N7Y A;  1O4G A;  5BO4 A;  1CWE A;  1XA6 A;  3BUW B;  3VS6 A;  1BG1 A;  1P13 A;  1O4F A;  5DC9 A;  3GQI B;  1AYA A;  1AB2 A;  2K79 B;  2RSY A;  3S8O A;  1BHF A;  1SPR A;  3VRO A;  2DLZ A;  1BFJ A;  5IBM A;  2QMS A;  2C0I A;  4NWF A;  4F59 A;  2ABL A;  2BBU A;  2XP1 A;  1B47 A;  2CI9 A;  5CDW A;  2CBL A;  1BKL A;  2H8H A;  2L3T A;  1BFI A;  1Z3K A;  2IZV A;  1SPS A;  1BF5 A;  3GXW A;  4WWQ A;  4K2R A;  3OP0 A;  4EY0 A;  2CIA A;  2KGY A;  1O45 A;  1F2F A;  1OO3 A;  5DC4 A;  1LUK A;  1JWO A;  2DLY A;  2OZO A;  4TZI A;  1FYR A;  1CWD L;  2K7A B;  2CS0 A;  2Y1M A;  3HHM B;  3PLF B;  5EEL A;  2FCI A;  1O4O A;  1LCJ A;  2SHP A;  3MXC A;  2EOB A;  1FMK A;  1A09 A;  2ECD A;  1Y1U A;  2Y3A B;  1A1C A;  1A1A A;  1SKJ A;  1AOT F;  4H34 A;  1O4L A;  1JU5 A;  4DGX A;  4LUD A;  3IN7 A;  3VS2 A;  1AYB A;  3S8N A;  1O48 A;  2LQW A;  3N84 A;  5EG3 B;  1O42 A;  1M27 A;  1RQQ C;  4M4Z A;  3M7F A;  1BLK A;  1O4D A;  1FU6 A;  1LUN A;  4QSY A;  1IS0 A;  2MRJ A;  2EYY A;  1OPL A;  1LKK A;  2ETZ A;  4FBN A;  1X27 A;  3VS7 A;  1AD5 A;  1O41 A;  2Y1N A;  4GL9 E;  1K9A A;  2PNB A;  4A4C A;  1QG1 E;  4XZ0 A;  3S8L A;  1LUI A;  5D0J A;  2HCK A;  4OHI A;  3MXY A;  5GJH A;  1OO4 A;  2OQ1 A;  4DGP A;  4JGH A;  1CSZ A;  1O4I A;  1O4K A;  2PTK A;  1BM2 A;  1QAD A;  3S9K A;  2HMH A;  4JE4 A;  1TZE E;  3WA4 A;  1A1E A;  2PLE A;  1AOU F;  4P9Z A;  3BUM B;  1MW4 A;  1IJR A;  4F5A A;  1GRI A;  3ZNI A;  2MC1 A;  1O4R A;  1UUS A;  3VS1 A;  1NRV A;  1MIL A;  2HDV A;  3UF4 A;  1G83 A;  1O4N A;  2IUI A;  1SHD A;  3BUN B;  1FU5 A;  5KAZ A;  3OV1 A;  1O4J A;  4LUE A;  3HCK A;  3VRP A;  2KNO A;  2SRC A;  1CJ1 A;  1JYU A;  4D8K A;  3TL0 A;  1O4P A;  2C0T A;  4H1O A;  3CBL A;  3PFV A;  5GJI A;  1GHU A;  2AOB A;  3K2M A;  2MQI A;  1O47 A;  1OPK A;  5HKY A;  3C7I A;  1KA7 A;  2DM0 A; 
#chains in the Genus database with same CATH homology
 1D4W A;  3T04 A;  3VS5 A;  1HCT B;  2VIF A;  5AXI A;  1O43 A;  3QWY A;  1R1S A;  4EIH A;  2LNW A;  1NZV A;  1JYR A;  2C9W A;  1LCK A;  4NWG A;  3IN8 A;  3EAC A;  1PIC A;  3PSJ A;  1O4B A;  1I3Z A;  2MK2 A;  2DVJ A;  1SHA A;  1BHH B;  2EYZ A;  2MRK A;  3PS5 A;  5I6V A;  3N8M A;  5AUL A;  4GPL B;  3VRZ A;  4K44 A;  2L4K A;  1FHS A;  4U17 A;  4OHH A;  4E68 A;  2L6K A;  2RMX A;  1UUR A;  1BHH A;  4OHD A;  2HUW A;  3PJP A;  1O4M A;  2EO3 A;  2HDX A;  1A08 A;  3GXX A;  4K45 A;  5J3X A;  5DF6 A;  2EYV A;  5HKW A;  3VS4 A;  3BKB A;  1BMB A;  3OB1 B;  2DCR A;  2FO0 A;  1D1Z A;  3VRY A;  3IMJ A;  4XZ1 A;  2EO6 A;  3MAZ A;  1O49 A;  4U1P A;  2JYQ A;  2IUG A;  3VS3 A;  1SHB A;  2AUG A;  2YU7 A;  3TKZ A;  1D4T A;  3OVE A;  2DX0 A;  4F5B A;  2ROR A;  2YSX A;  2IUH A;  2CRH A;  5HKZ A;  1TCE A;  4E93 A;  1O4C A;  4GWF A;  1BLJ A;  1O4E A;  1O4Q A;  4JEG A;  2LQN A;  1FBV A;  4OHE A;  2C0O A;  1A07 A;  3PSK A;  4ROJ A;  3IMD A;  4L1B B;  5EHR A;  2PNA A;  3VRR A;  4FL2 A;  2H5K A;  2CI8 A;  3CD3 A;  3KFJ A;  3VRQ A;  4K11 A;  3CWG A;  4OHL A;  3PQZ A;  1BKM A;  1JYQ A;  1ZFP E;  2RVF A;  2GSB A;  5EEQ A;  1AYD A;  3VRN A;  2PLD A;  1FBZ A;  1M61 A;  4X6S A;  2AOA A;  1Y57 A;  1KC2 A;  3UYO A;  3CXL A;  2EU0 A;  1R1Q A;  1X0N A;  1O4A A;  1RPY A;  1F1W A;  3BUX B;  2H46 E;  1QCF A;  3OB2 B;  1A81 A;  3QWX X;  1A1B A;  4FL3 A;  5EHP A;  5DC0 B;  1NZL A;  2KK6 A;  2EKX A;  1R1P A;  3VGO A;  3EAZ A;  2B3O A;  1WQU A;  5IBS A;  4P9V A;  1O44 A;  2CR4 A;  3HIZ B;  1LKL A;  1CSY A;  1YVL A;  3VS0 A;  2EL8 A;  2LCT A;  1KSW A;  1O46 A;  1H9O A;  3NHN A;  2LNX A;  1AYC A;  1RJA A;  3BUO B;  1YVH A;  4A4B A;  1X6C A;  1HCS B;  1KA6 A;  2GE9 A;  1LUM A;  3US4 A;  1O4H A;  3N7Y A;  1O4G A;  5BO4 A;  1CWE A;  1XA6 A;  3BUW B;  3VS6 A;  1BG1 A;  1P13 A;  1O4F A;  5DC9 A;  3GQI B;  1AYA A;  1AB2 A;  2K79 B;  2RSY A;  3S8O A;  1BHF A;  1SPR A;  3VRO A;  2DLZ A;  1BFJ A;  5IBM A;  2QMS A;  2C0I A;  4NWF A;  4F59 A;  2ABL A;  2BBU A;  2XP1 A;  1B47 A;  2CI9 A;  5CDW A;  2CBL A;  1BKL A;  2H8H A;  2L3T A;  1BFI A;  1Z3K A;  2IZV A;  1SPS A;  1BF5 A;  3GXW A;  4WWQ A;  4K2R A;  3OP0 A;  4EY0 A;  2CIA A;  1O45 A;  1F2F A;  1OO3 A;  5DC4 A;  1LUK A;  1JWO A;  2DLY A;  2OZO A;  4TZI A;  1FYR A;  1CWD L;  2K7A B;  2CS0 A;  2Y1M A;  3HHM B;  3PLF B;  5EEL A;  2FCI A;  1O4O A;  1LCJ A;  2SHP A;  3MXC A;  2EOB A;  1FMK A;  1A09 A;  2ECD A;  1Y1U A;  2Y3A B;  1A1C A;  1A1A A;  1SKJ A;  1AOT F;  4H34 A;  1O4L A;  1JU5 A;  4DGX A;  4LUD A;  3IN7 A;  3VS2 A;  1AYB A;  3S8N A;  1O48 A;  2LQW A;  3N84 A;  5EG3 B;  1O42 A;  1M27 A;  1RQQ C;  4M4Z A;  3M7F A;  1BLK A;  1O4D A;  1FU6 A;  1LUN A;  4QSY A;  1IS0 A;  2MRJ A;  2EYY A;  1OPL A;  1LKK A;  2ETZ A;  4FBN A;  1X27 A;  3VS7 A;  1AD5 A;  1O41 A;  2Y1N A;  4GL9 E;  1K9A A;  2PNB A;  4A4C A;  1QG1 E;  4XZ0 A;  3S8L A;  1LUI A;  5D0J A;  2HCK A;  4OHI A;  3MXY A;  5GJH A;  1OO4 A;  2OQ1 A;  4DGP A;  4JGH A;  1CSZ A;  1O4I A;  1O4K A;  2PTK A;  1BM2 A;  1QAD A;  3S9K A;  2HMH A;  4JE4 A;  1TZE E;  3WA4 A;  1A1E A;  2PLE A;  1AOU F;  4P9Z A;  3BUM B;  1MW4 A;  1IJR A;  4F5A A;  1GRI A;  3ZNI A;  2MC1 A;  1O4R A;  1UUS A;  3VS1 A;  1NRV A;  1MIL A;  2HDV A;  3UF4 A;  1G83 A;  1O4N A;  2IUI A;  1SHD A;  3BUN B;  1FU5 A;  5KAZ A;  3OV1 A;  1O4J A;  4LUE A;  3HCK A;  3VRP A;  2KNO A;  2SRC A;  1CJ1 A;  1JYU A;  4D8K A;  3TL0 A;  1O4P A;  2C0T A;  4H1O A;  3CBL A;  3PFV A;  5GJI A;  1GHU A;  2AOB A;  3K2M A;  2MQI A;  1O47 A;  1OPK A;  5HKY A;  3C7I A;  1KA7 A;  2DM0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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