1AYAA

Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
101
structure length
101
Chain Sequence
MRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
pubmed doi rcsb
molecule tags Hydrolase(sh2 domain)
source organism Mus musculus
molecule keywords PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
total genus 24
structure length 101
sequence length 101
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 1994-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1ayaA00
1A08A 1JU5A 1AYAA 4NWFA 1AYCA 2MC1A 5D0JA 1CSYA 2DLZA 4QSYA 4XZ0A 3HCKA 1TZEE 4E68A 3VS4A 3N84A 2CI8A 3MAZA 1YVHA 1SPRA 4F5BA 3IN7A 3S8NA 4K2RA 1I3ZA 4JE4A 1FYRA 2FCIA 3PLFB 4GL9E 3TKZA 4XZ1A 3VS2A 1CJ1A 2KNOA 4A4CA 4FL2A 2IZVA 1R1PA 1O4HA 1O4JA 2OQ1A 2H46E 3MXCA 3EACA 2CR4A 3WA4A 2H8HA 2HDVA 3VS7A 1HCSB 2LCTA 5HKYA 1M61A 2EOBA 2CRHA 1LKKA 3IN8A 3OVEA 2K7AB 4NWGA 1O43A 2AOBA 1KA7A 4F59A 4P9ZA 3N7YA 1FU6A 1A09A 3VS0A 3US4A 1JYQA 2PLDA 5DC0B 3PQZA 3HIZB 2B3OA 1O4RA 1IS0A 4FL3A 3GXWA 4OHHA 3VS3A 1LUIA 3VROA 1ZFPE 1BFIA 1TCEA 1O41A 3S8LA 1IJRA 3VRPA 1O4CA 1MILA 2Y1NA 1BLKA 1O4GA 5EG3B 3MXYA 1AOUF 1D4WA 2PTKA 2EYVA 4EY0A 1BHFA 1KC2A 1A1AA 2OZOA 5KAZA 2LNWA 2VIFA 2LQNA 3BUNB 3QWXX 3CXLA 2PLEA 1NZVA 4L1BB 1RQQC 2L4KA 1YVLA 1O44A 1K9AA 2AOAA 2HDXA 4FBNA 1O45A 1CWDL 2SRCA 1FU5A 3S8OA 2DM0A 5DC9A 2AUGA 3NHNA 3PSKA 3T04A 2PNBA 2C0IA 5CDWA 3CBLA 2HMHA 1LCJA 2MK2A 4OHIA 2YSXA 5IBMA 4U1PA 1O4EA 2RSYA 2IUHA 2EU0A 3BUWB 1X27A 2C0OA 1BHHA 1AD5A 5J3XA 2K79B 1O42A 4E93A 3BUMB 2XP1A 1QCFA 2LQWA 1BLJA 2MRKA 1O4OA 1R1QA 1D4TA 2CI9A 4H34A 1G83A 3VS1A 5EHPA 1BKMA 1O4KA 2EYYA 2ECDA 1CSZA 4K11A 2EYZA 1O4DA 1PICA 1HCTB 3M7FA 1GHUA 4OHDA 1QG1E 2BBUA 1XA6A 2SHPA 2HUWA 1A1BA 1OO4A 1O4FA 4M4ZA 3VGOA 2L3TA 5GJHA 1AB2A 1A07A 5EHRA 1Y1UA 1Y57A 1AOTF 3CD3A 2DX0A 1X0NA 3GXXA 1P13A 1JYUA 4U17A 2DVJA 3GQIB 4JGHA 5GJIA 3IMJA 3PSJA 4OHEA 1WQUA 3K2MA 3N8MA 4DGPA 1FBZA 1O49A 3UYOA 1KSWA 1SHDA 2KK6A 1X6CA 1FHSA 5IBSA 4TZIA 5HKZA 3CWGA 1H9OA 3OB1B 2IUIA 3BKBA 4JEGA 1O4LA 1BF5A 1OPKA 4WWQA 1NRVA 3VRNA 2DLYA 4EIHA 3BUXB 1B47A 5DF6A 1LUKA 4D8KA 2GE9A 2RVFA 3KFJA 5EEQA 1A1EA 2H5KA 3OV1A 3ZNIA 4DGXA 5HKWA 2EO6A 4X6SA 3VRQA 2GSBA 5BO4A 1O4AA 1O4MA 5DC4A 1LUNA 1O4BA 2C0TA 4H1OA 1BMBA 3PS5A 1SKJA 2PNAA 1Z3KA 2IUGA 3VS5A 1RPYA 2FO0A 2MRJA 1FMKA 1OO3A 1O4QA 3VRZA 4GPLB 3HHMB 1BG1A 2DCRA 3IMDA 1O4PA 1OPLA 2EKXA 2Y3AB 5I6VA 1O48A 5EELA 1M27A 4OHLA 3VS6A 1KA6A 1SPSA 1D1ZA 1AYDA 4K44A 2EO3A 2RORA 4F5AA 3OP0A 2JYQA 1O4NA 2Y1MA 2RMXA 3PFVA 4K45A 1BHHB 4A4BA 2LNXA 4LUEA 1UURA 2L6KA 5AULA 4GWFA 1O47A 2EL8A 1CWEA 1SHAA 4ROJA 4P9VA 1JWOA 3C7IA 3BUOB 2QMSA 5AXIA 1LUMA 1BFJA 2CBLA 2C9WA 2CS0A 3QWYA 1MW4A 2ETZA 1A1CA 1R1SA 3VRRA 2HCKA 3TL0A 1BM2A 4LUDA 1JYRA 1LKLA 3VRYA 1FBVA 1GRIA 1UUSA 1F1WA 3PJPA 3UF4A 1O4IA 3S9KA 1O46A 1QADA 3EAZA 1NZLA 3OB2B 1AYBA 1A81A 2MQIA 2CIAA 1F2FA 1SHBA 1BKLA 1RJAA 2ABLA 1LCKA 2YU7A
chains in the Genus database with same CATH superfamily
1A08A 1JU5A 1AYAA 4NWFA 1AYCA 2MC1A 5D0JA 1CSYA 2DLZA 4QSYA 4XZ0A 3HCKA 1TZEE 4E68A 3VS4A 3N84A 2CI8A 3MAZA 1YVHA 1SPRA 4F5BA 3IN7A 3S8NA 4K2RA 1I3ZA 4JE4A 1FYRA 2FCIA 3PLFB 4GL9E 3TKZA 4XZ1A 3VS2A 1CJ1A 2KNOA 4A4CA 4FL2A 2IZVA 1R1PA 1O4HA 1O4JA 2OQ1A 2H46E 3MXCA 3EACA 2CR4A 3WA4A 2H8HA 2HDVA 3VS7A 1HCSB 2LCTA 5HKYA 1M61A 2EOBA 2CRHA 1LKKA 3IN8A 3OVEA 2K7AB 4NWGA 1O43A 2AOBA 1KA7A 4F59A 4P9ZA 3N7YA 1FU6A 1A09A 3VS0A 3US4A 1JYQA 2PLDA 5DC0B 3PQZA 3HIZB 2B3OA 1O4RA 1IS0A 4FL3A 3GXWA 4OHHA 3VS3A 1LUIA 3VROA 1ZFPE 1BFIA 1TCEA 1O41A 3S8LA 1IJRA 3K2TA 3VRPA 1O4CA 1MILA 2Y1NA 1BLKA 1O4GA 5EG3B 3MXYA 1AOUF 1D4WA 2PTKA 2EYVA 4EY0A 1BHFA 1KC2A 1A1AA 2OZOA 5KAZA 2LNWA 2VIFA 2LQNA 3BUNB 3QWXX 3CXLA 2PLEA 1NZVA 4L1BB 1RQQC 2L4KA 1YVLA 1O44A 1K9AA 2AOAA 2HDXA 4FBNA 1O45A 1CWDL 2SRCA 1FU5A 3S8OA 2DM0A 5DC9A 2AUGA 3NHNA 3PSKA 3T04A 2PNBA 2C0IA 5CDWA 3CBLA 2HMHA 1LCJA 2MK2A 4OHIA 2YSXA 5IBMA 4U1PA 1O4EA 2RSYA 2IUHA 2EU0A 3BUWB 1X27A 2C0OA 1BHHA 1AD5A 5J3XA 2K79B 1O42A 4E93A 3BUMB 2XP1A 1QCFA 2LQWA 1BLJA 2MRKA 1O4OA 1R1QA 1D4TA 2CI9A 4H34A 1G83A 3VS1A 5EHPA 1BKMA 1O4KA 2EYYA 2ECDA 1CSZA 4K11A 2EYZA 1O4DA 1PICA 1HCTB 3M7FA 1GHUA 4OHDA 1QG1E 2BBUA 1XA6A 2SHPA 2HUWA 1A1BA 1OO4A 1O4FA 4M4ZA 3VGOA 2L3TA 5GJHA 1AB2A 1A07A 5EHRA 1Y1UA 1Y57A 1AOTF 2LRAA 3CD3A 2DX0A 1X0NA 3GXXA 1P13A 1JYUA 4U17A 2DVJA 3GQIB 4JGHA 5GJIA 3IMJA 3PSJA 4OHEA 1WQUA 3K2MA 3N8MA 4DGPA 1FBZA 1O49A 3UYOA 1KSWA 1SHDA 2KK6A 1X6CA 1FHSA 5IBSA 4TZIA 5HKZA 3CWGA 1H9OA 3OB1B 2IUIA 3BKBA 4JEGA 1O4LA 1BF5A 1OPKA 4WWQA 1NRVA 3VRNA 2DLYA 4EIHA 3BUXB 1B47A 5DF6A 1LUKA 4D8KA 2GE9A 2RVFA 3KFJA 5EEQA 1A1EA 2H5KA 3OV1A 3ZNIA 3LYVA 4DGXA 2KGYA 5HKWA 2EO6A 4X6SA 3VRQA 2GSBA 5BO4A 1O4AA 1O4MA 5DC4A 1LUNA 1O4BA 2C0TA 4H1OA 1BMBA 3PS5A 1SKJA 2PNAA 1Z3KA 2IUGA 3VS5A 1RPYA 2FO0A 2MRJA 1FMKA 1OO3A 1O4QA 3VRZA 4GPLB 3HHMB 1BG1A 2DCRA 3IMDA 1O4PA 1OPLA 2EKXA 2Y3AB 5I6VA 1O48A 5EELA 1M27A 4OHLA 3VS6A 1KA6A 1SPSA 1D1ZA 1AYDA 4K44A 2EO3A 2RORA 4F5AA 3OP0A 2JYQA 1O4NA 2Y1MA 2RMXA 3PFVA 4K45A 1BHHB 4A4BA 2LNXA 4LUEA 1UURA 2L6KA 5AULA 4GWFA 1O47A 2EL8A 1CWEA 1SHAA 4ROJA 4P9VA 1JWOA 3C7IA 3BUOB 2QMSA 5AXIA 1LUMA 1BFJA 2CBLA 2C9WA 2CS0A 3QWYA 1MW4A 2ETZA 1A1CA 1R1SA 3VRRA 2HCKA 3TL0A 1BM2A 4LUDA 1JYRA 1LKLA 3VRYA 1FBVA 1GRIA 1UUSA 1F1WA 3PJPA 3UF4A 1O4IA 3S9KA 1O46A 1QADA 3EAZA 1NZLA 3OB2B 1AYBA 1A81A 2MQIA 2CIAA 1F2FA 1SHBA 1BKLA 1RJAA 2ABLA 1LCKA 2YU7A
chains in the Genus database with same CATH topology
1A08A 1JU5A 1AYAA 4NWFA 1AYCA 2MC1A 5D0JA 1CSYA 2DLZA 4QSYA 4XZ0A 3HCKA 1TZEE 4E68A 3VS4A 3N84A 2CI8A 3MAZA 1YVHA 1SPRA 4F5BA 3IN7A 3S8NA 4K2RA 1I3ZA 4JE4A 1FYRA 2FCIA 3PLFB 4GL9E 3TKZA 4XZ1A 3VS2A 1CJ1A 2KNOA 4A4CA 4FL2A 2IZVA 1R1PA 1O4HA 1O4JA 2OQ1A 2H46E 3MXCA 3EACA 2CR4A 3WA4A 2H8HA 2HDVA 3VS7A 1HCSB 2LCTA 5HKYA 1M61A 2EOBA 2CRHA 1LKKA 3IN8A 3OVEA 2K7AB 4NWGA 1O43A 2AOBA 1KA7A 4F59A 4P9ZA 3N7YA 1FU6A 1A09A 3VS0A 3US4A 1JYQA 2PLDA 5DC0B 3PQZA 3HIZB 2B3OA 1O4RA 1IS0A 4FL3A 3GXWA 4OHHA 3VS3A 1LUIA 3VROA 1ZFPE 1BFIA 1TCEA 1O41A 3S8LA 1IJRA 3VRPA 1O4CA 1MILA 2Y1NA 1BLKA 1O4GA 5EG3B 3MXYA 1AOUF 1D4WA 2PTKA 2EYVA 4EY0A 1BHFA 1KC2A 1A1AA 2OZOA 5KAZA 2LNWA 2VIFA 2LQNA 3BUNB 3QWXX 3CXLA 2PLEA 1NZVA 4L1BB 1RQQC 2L4KA 1YVLA 1O44A 1K9AA 2AOAA 2HDXA 4FBNA 1O45A 1CWDL 2SRCA 1FU5A 3S8OA 2DM0A 5DC9A 2AUGA 3NHNA 3PSKA 3T04A 2PNBA 2C0IA 5CDWA 3CBLA 2HMHA 1LCJA 2MK2A 4OHIA 2YSXA 5IBMA 4U1PA 1O4EA 2RSYA 2IUHA 2EU0A 3BUWB 1X27A 2C0OA 1BHHA 1AD5A 5J3XA 2K79B 1O42A 4E93A 3BUMB 2XP1A 1QCFA 2LQWA 1BLJA 2MRKA 1O4OA 1R1QA 1D4TA 2CI9A 4H34A 1G83A 3VS1A 5EHPA 1BKMA 1O4KA 2EYYA 2ECDA 1CSZA 4K11A 2EYZA 1O4DA 1PICA 1HCTB 3M7FA 1GHUA 4OHDA 1QG1E 2BBUA 1XA6A 2SHPA 2HUWA 1A1BA 1OO4A 1O4FA 4M4ZA 3VGOA 2L3TA 5GJHA 1AB2A 1A07A 5EHRA 1Y1UA 1Y57A 1AOTF 3CD3A 2DX0A 1X0NA 3GXXA 1P13A 1JYUA 4U17A 2DVJA 3GQIB 4JGHA 5GJIA 3IMJA 3PSJA 4OHEA 1WQUA 3K2MA 3N8MA 4DGPA 1FBZA 1O49A 3UYOA 1KSWA 1SHDA 2KK6A 1X6CA 1FHSA 5IBSA 4TZIA 5HKZA 3CWGA 1H9OA 3OB1B 2IUIA 3BKBA 4JEGA 1O4LA 1BF5A 1OPKA 4WWQA 1NRVA 3VRNA 2DLYA 4EIHA 3BUXB 1B47A 5DF6A 1LUKA 4D8KA 2GE9A 2RVFA 3KFJA 5EEQA 1A1EA 2H5KA 3OV1A 3ZNIA 4DGXA 5HKWA 2EO6A 4X6SA 3VRQA 2GSBA 5BO4A 1O4AA 1O4MA 5DC4A 1LUNA 1O4BA 2C0TA 4H1OA 1BMBA 3PS5A 1SKJA 2PNAA 1Z3KA 2IUGA 3VS5A 1RPYA 2FO0A 2MRJA 1FMKA 1OO3A 1O4QA 3VRZA 4GPLB 3HHMB 1BG1A 2DCRA 3IMDA 1O4PA 1OPLA 2EKXA 2Y3AB 5I6VA 1O48A 5EELA 1M27A 4OHLA 3VS6A 1KA6A 1SPSA 1D1ZA 1AYDA 4K44A 2EO3A 2RORA 4F5AA 3OP0A 2JYQA 1O4NA 2Y1MA 2RMXA 3PFVA 4K45A 1BHHB 4A4BA 2LNXA 4LUEA 1UURA 2L6KA 5AULA 4GWFA 1O47A 2EL8A 1CWEA 1SHAA 4ROJA 4P9VA 1JWOA 3C7IA 3BUOB 2QMSA 5AXIA 1LUMA 1BFJA 2CBLA 2C9WA 2CS0A 3QWYA 1MW4A 2ETZA 1A1CA 1R1SA 3VRRA 2HCKA 3TL0A 1BM2A 4LUDA 1JYRA 1LKLA 3VRYA 1FBVA 1GRIA 1UUSA 1F1WA 3PJPA 3UF4A 1O4IA 3S9KA 1O46A 1QADA 3EAZA 1NZLA 3OB2B 1AYBA 1A81A 2MQIA 2CIAA 1F2FA 1SHBA 1BKLA 1RJAA 2ABLA 1LCKA 2YU7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A08 A;  1JU5 A;  1AYA A;  4NWF A;  1AYC A;  2MC1 A;  5D0J A;  1CSY A;  2DLZ A;  4QSY A;  4XZ0 A;  3HCK A;  1TZE E;  4E68 A;  3VS4 A;  3N84 A;  2CI8 A;  3MAZ A;  1YVH A;  1SPR A;  4F5B A;  3IN7 A;  3S8N A;  4K2R A;  1I3Z A;  4JE4 A;  1FYR A;  2FCI A;  3PLF B;  4GL9 E;  3TKZ A;  4XZ1 A;  3VS2 A;  1CJ1 A;  2KNO A;  4A4C A;  4FL2 A;  2IZV A;  1R1P A;  1O4H A;  1O4J A;  2OQ1 A;  2H46 E;  3MXC A;  3EAC A;  2CR4 A;  3WA4 A;  2H8H A;  2HDV A;  3VS7 A;  1HCS B;  2LCT A;  5HKY A;  1M61 A;  2EOB A;  2CRH A;  1LKK A;  3IN8 A;  3OVE A;  2K7A B;  4NWG A;  1O43 A;  2AOB A;  1KA7 A;  4F59 A;  4P9Z A;  3N7Y A;  1FU6 A;  1A09 A;  3VS0 A;  3US4 A;  1JYQ A;  2PLD A;  5DC0 B;  3PQZ A;  3HIZ B;  2B3O A;  1O4R A;  1IS0 A;  4FL3 A;  3GXW A;  4OHH A;  3VS3 A;  1LUI A;  3VRO A;  1ZFP E;  1BFI A;  1TCE A;  1O41 A;  3S8L A;  1IJR A;  3VRP A;  1O4C A;  1MIL A;  2Y1N A;  1BLK A;  1O4G A;  5EG3 B;  3MXY A;  1AOU F;  1D4W A;  2PTK A;  2EYV A;  4EY0 A;  1BHF A;  1KC2 A;  1A1A A;  2OZO A;  5KAZ A;  2LNW A;  2VIF A;  2LQN A;  3BUN B;  3QWX X;  3CXL A;  2PLE A;  1NZV A;  4L1B B;  1RQQ C;  2L4K A;  1YVL A;  1O44 A;  1K9A A;  2AOA A;  2HDX A;  4FBN A;  1O45 A;  1CWD L;  2SRC A;  1FU5 A;  3S8O A;  2DM0 A;  5DC9 A;  2AUG A;  3NHN A;  3PSK A;  3T04 A;  2PNB A;  2C0I A;  5CDW A;  3CBL A;  2HMH A;  1LCJ A;  2MK2 A;  4OHI A;  2YSX A;  5IBM A;  4U1P A;  1O4E A;  2RSY A;  2IUH A;  2EU0 A;  3BUW B;  1X27 A;  2C0O A;  1BHH A;  1AD5 A;  5J3X A;  2K79 B;  1O42 A;  4E93 A;  3BUM B;  2XP1 A;  1QCF A;  2LQW A;  1BLJ A;  2MRK A;  1O4O A;  1R1Q A;  1D4T A;  2CI9 A;  4H34 A;  1G83 A;  3VS1 A;  5EHP A;  1BKM A;  1O4K A;  2EYY A;  2ECD A;  1CSZ A;  4K11 A;  2EYZ A;  1O4D A;  1PIC A;  1HCT B;  3M7F A;  1GHU A;  4OHD A;  1QG1 E;  2BBU A;  1XA6 A;  2SHP A;  2HUW A;  1A1B A;  1OO4 A;  1O4F A;  4M4Z A;  3VGO A;  2L3T A;  5GJH A;  1AB2 A;  1A07 A;  5EHR A;  1Y1U A;  1Y57 A;  1AOT F;  3CD3 A;  2DX0 A;  1X0N A;  3GXX A;  1P13 A;  1JYU A;  4U17 A;  2DVJ A;  3GQI B;  4JGH A;  5GJI A;  3IMJ A;  3PSJ A;  4OHE A;  1WQU A;  3K2M A;  3N8M A;  4DGP A;  1FBZ A;  1O49 A;  3UYO A;  1KSW A;  1SHD A;  2KK6 A;  1X6C A;  1FHS A;  5IBS A;  4TZI A;  5HKZ A;  3CWG A;  1H9O A;  3OB1 B;  2IUI A;  3BKB A;  4JEG A;  1O4L A;  1BF5 A;  1OPK A;  4WWQ A;  1NRV A;  3VRN A;  2DLY A;  4EIH A;  3BUX B;  1B47 A;  5DF6 A;  1LUK A;  4D8K A;  2GE9 A;  2RVF A;  3KFJ A;  5EEQ A;  1A1E A;  2H5K A;  3OV1 A;  3ZNI A;  4DGX A;  5HKW A;  2EO6 A;  4X6S A;  3VRQ A;  2GSB A;  5BO4 A;  1O4A A;  1O4M A;  5DC4 A;  1LUN A;  1O4B A;  2C0T A;  4H1O A;  1BMB A;  3PS5 A;  1SKJ A;  2PNA A;  1Z3K A;  2IUG A;  3VS5 A;  1RPY A;  2FO0 A;  2MRJ A;  1FMK A;  1OO3 A;  1O4Q A;  3VRZ A;  4GPL B;  3HHM B;  1BG1 A;  2DCR A;  3IMD A;  1O4P A;  1OPL A;  2EKX A;  2Y3A B;  5I6V A;  1O48 A;  5EEL A;  1M27 A;  4OHL A;  3VS6 A;  1KA6 A;  1SPS A;  1D1Z A;  1AYD A;  4K44 A;  2EO3 A;  2ROR A;  4F5A A;  3OP0 A;  2JYQ A;  1O4N A;  2Y1M A;  2RMX A;  3PFV A;  4K45 A;  1BHH B;  4A4B A;  2LNX A;  4LUE A;  1UUR A;  2L6K A;  5AUL A;  4GWF A;  1O47 A;  2EL8 A;  1CWE A;  1SHA A;  4ROJ A;  4P9V A;  1JWO A;  3C7I A;  3BUO B;  2QMS A;  5AXI A;  1LUM A;  1BFJ A;  2CBL A;  2C9W A;  2CS0 A;  3QWY A;  1MW4 A;  2ETZ A;  1A1C A;  1R1S A;  3VRR A;  2HCK A;  3TL0 A;  1BM2 A;  4LUD A;  1JYR A;  1LKL A;  3VRY A;  1FBV A;  1GRI A;  1UUS A;  1F1W A;  3PJP A;  3UF4 A;  1O4I A;  3S9K A;  1O46 A;  1QAD A;  3EAZ A;  1NZL A;  3OB2 B;  1AYB A;  1A81 A;  2MQI A;  2CIA A;  1F2F A;  1SHB A;  1BKL A;  1RJA A;  2ABL A;  1LCK A;  2YU7 A; 
#chains in the Genus database with same CATH topology
 1A08 A;  1JU5 A;  1AYA A;  4NWF A;  1AYC A;  2MC1 A;  5D0J A;  1CSY A;  2DLZ A;  4QSY A;  4XZ0 A;  3HCK A;  1TZE E;  4E68 A;  3VS4 A;  3N84 A;  2CI8 A;  3MAZ A;  1YVH A;  1SPR A;  4F5B A;  3IN7 A;  3S8N A;  4K2R A;  1I3Z A;  4JE4 A;  1FYR A;  2FCI A;  3PLF B;  4GL9 E;  3TKZ A;  4XZ1 A;  3VS2 A;  1CJ1 A;  2KNO A;  4A4C A;  4FL2 A;  2IZV A;  1R1P A;  1O4H A;  1O4J A;  2OQ1 A;  2H46 E;  3MXC A;  3EAC A;  2CR4 A;  3WA4 A;  2H8H A;  2HDV A;  3VS7 A;  1HCS B;  2LCT A;  5HKY A;  1M61 A;  2EOB A;  2CRH A;  1LKK A;  3IN8 A;  3OVE A;  2K7A B;  4NWG A;  1O43 A;  2AOB A;  1KA7 A;  4F59 A;  4P9Z A;  3N7Y A;  1FU6 A;  1A09 A;  3VS0 A;  3US4 A;  1JYQ A;  2PLD A;  5DC0 B;  3PQZ A;  3HIZ B;  2B3O A;  1O4R A;  1IS0 A;  4FL3 A;  3GXW A;  4OHH A;  3VS3 A;  1LUI A;  3VRO A;  1ZFP E;  1BFI A;  1TCE A;  1O41 A;  3S8L A;  1IJR A;  3K2T A;  3VRP A;  1O4C A;  1MIL A;  2Y1N A;  1BLK A;  1O4G A;  5EG3 B;  3MXY A;  1AOU F;  1D4W A;  2PTK A;  2EYV A;  4EY0 A;  1BHF A;  1KC2 A;  1A1A A;  2OZO A;  5KAZ A;  2LNW A;  2VIF A;  2LQN A;  3BUN B;  3QWX X;  3CXL A;  2PLE A;  1NZV A;  4L1B B;  1RQQ C;  2L4K A;  1YVL A;  1O44 A;  1K9A A;  2AOA A;  2HDX A;  4FBN A;  1O45 A;  1CWD L;  2SRC A;  1FU5 A;  3S8O A;  2DM0 A;  5DC9 A;  2AUG A;  3NHN A;  3PSK A;  3T04 A;  2PNB A;  2C0I A;  5CDW A;  3CBL A;  2HMH A;  1LCJ A;  2MK2 A;  4OHI A;  2YSX A;  5IBM A;  4U1P A;  1O4E A;  2RSY A;  2IUH A;  2EU0 A;  3BUW B;  1X27 A;  2C0O A;  1BHH A;  1AD5 A;  5J3X A;  2K79 B;  1O42 A;  4E93 A;  3BUM B;  2XP1 A;  1QCF A;  2LQW A;  1BLJ A;  2MRK A;  1O4O A;  1R1Q A;  1D4T A;  2CI9 A;  4H34 A;  1G83 A;  3VS1 A;  5EHP A;  1BKM A;  1O4K A;  2EYY A;  2ECD A;  1CSZ A;  4K11 A;  2EYZ A;  1O4D A;  1PIC A;  1HCT B;  3M7F A;  1GHU A;  4OHD A;  1QG1 E;  2BBU A;  1XA6 A;  2SHP A;  2HUW A;  1A1B A;  1OO4 A;  1O4F A;  4M4Z A;  3VGO A;  2L3T A;  5GJH A;  1AB2 A;  1A07 A;  5EHR A;  1Y1U A;  1Y57 A;  1AOT F;  2LRA A;  3CD3 A;  2DX0 A;  1X0N A;  3GXX A;  1P13 A;  1JYU A;  4U17 A;  2DVJ A;  3GQI B;  4JGH A;  5GJI A;  3IMJ A;  3PSJ A;  4OHE A;  1WQU A;  3K2M A;  3N8M A;  4DGP A;  1FBZ A;  1O49 A;  3UYO A;  1KSW A;  1SHD A;  2KK6 A;  1X6C A;  1FHS A;  5IBS A;  4TZI A;  5HKZ A;  3CWG A;  1H9O A;  3OB1 B;  2IUI A;  3BKB A;  4JEG A;  1O4L A;  1BF5 A;  1OPK A;  4WWQ A;  1NRV A;  3VRN A;  2DLY A;  4EIH A;  3BUX B;  1B47 A;  5DF6 A;  1LUK A;  4D8K A;  2GE9 A;  2RVF A;  3KFJ A;  5EEQ A;  1A1E A;  2H5K A;  3OV1 A;  3ZNI A;  3LYV A;  4DGX A;  2KGY A;  5HKW A;  2EO6 A;  4X6S A;  3VRQ A;  2GSB A;  5BO4 A;  1O4A A;  1O4M A;  5DC4 A;  1LUN A;  1O4B A;  2C0T A;  4H1O A;  1BMB A;  3PS5 A;  1SKJ A;  2PNA A;  1Z3K A;  2IUG A;  3VS5 A;  1RPY A;  2FO0 A;  2MRJ A;  1FMK A;  1OO3 A;  1O4Q A;  3VRZ A;  4GPL B;  3HHM B;  1BG1 A;  2DCR A;  3IMD A;  1O4P A;  1OPL A;  2EKX A;  2Y3A B;  5I6V A;  1O48 A;  5EEL A;  1M27 A;  4OHL A;  3VS6 A;  1KA6 A;  1SPS A;  1D1Z A;  1AYD A;  4K44 A;  2EO3 A;  2ROR A;  4F5A A;  3OP0 A;  2JYQ A;  1O4N A;  2Y1M A;  2RMX A;  3PFV A;  4K45 A;  1BHH B;  4A4B A;  2LNX A;  4LUE A;  1UUR A;  2L6K A;  5AUL A;  4GWF A;  1O47 A;  2EL8 A;  1CWE A;  1SHA A;  4ROJ A;  4P9V A;  1JWO A;  3C7I A;  3BUO B;  2QMS A;  5AXI A;  1LUM A;  1BFJ A;  2CBL A;  2C9W A;  2CS0 A;  3QWY A;  1MW4 A;  2ETZ A;  1A1C A;  1R1S A;  3VRR A;  2HCK A;  3TL0 A;  1BM2 A;  4LUD A;  1JYR A;  1LKL A;  3VRY A;  1FBV A;  1GRI A;  1UUS A;  1F1W A;  3PJP A;  3UF4 A;  1O4I A;  3S9K A;  1O46 A;  1QAD A;  3EAZ A;  1NZL A;  3OB2 B;  1AYB A;  1A81 A;  2MQI A;  2CIA A;  1F2F A;  1SHB A;  1BKL A;  1RJA A;  2ABL A;  1LCK A;  2YU7 A; 
#chains in the Genus database with same CATH homology
 1A08 A;  1JU5 A;  1AYA A;  4NWF A;  1AYC A;  2MC1 A;  5D0J A;  1CSY A;  2DLZ A;  4QSY A;  4XZ0 A;  3HCK A;  1TZE E;  4E68 A;  3VS4 A;  3N84 A;  2CI8 A;  3MAZ A;  1YVH A;  1SPR A;  4F5B A;  3IN7 A;  3S8N A;  4K2R A;  1I3Z A;  4JE4 A;  1FYR A;  2FCI A;  3PLF B;  4GL9 E;  3TKZ A;  4XZ1 A;  3VS2 A;  1CJ1 A;  2KNO A;  4A4C A;  4FL2 A;  2IZV A;  1R1P A;  1O4H A;  1O4J A;  2OQ1 A;  2H46 E;  3MXC A;  3EAC A;  2CR4 A;  3WA4 A;  2H8H A;  2HDV A;  3VS7 A;  1HCS B;  2LCT A;  5HKY A;  1M61 A;  2EOB A;  2CRH A;  1LKK A;  3IN8 A;  3OVE A;  2K7A B;  4NWG A;  1O43 A;  2AOB A;  1KA7 A;  4F59 A;  4P9Z A;  3N7Y A;  1FU6 A;  1A09 A;  3VS0 A;  3US4 A;  1JYQ A;  2PLD A;  5DC0 B;  3PQZ A;  3HIZ B;  2B3O A;  1O4R A;  1IS0 A;  4FL3 A;  3GXW A;  4OHH A;  3VS3 A;  1LUI A;  3VRO A;  1ZFP E;  1BFI A;  1TCE A;  1O41 A;  3S8L A;  1IJR A;  3VRP A;  1O4C A;  1MIL A;  2Y1N A;  1BLK A;  1O4G A;  5EG3 B;  3MXY A;  1AOU F;  1D4W A;  2PTK A;  2EYV A;  4EY0 A;  1BHF A;  1KC2 A;  1A1A A;  2OZO A;  5KAZ A;  2LNW A;  2VIF A;  2LQN A;  3BUN B;  3QWX X;  3CXL A;  2PLE A;  1NZV A;  4L1B B;  1RQQ C;  2L4K A;  1YVL A;  1O44 A;  1K9A A;  2AOA A;  2HDX A;  4FBN A;  1O45 A;  1CWD L;  2SRC A;  1FU5 A;  3S8O A;  2DM0 A;  5DC9 A;  2AUG A;  3NHN A;  3PSK A;  3T04 A;  2PNB A;  2C0I A;  5CDW A;  3CBL A;  2HMH A;  1LCJ A;  2MK2 A;  4OHI A;  2YSX A;  5IBM A;  4U1P A;  1O4E A;  2RSY A;  2IUH A;  2EU0 A;  3BUW B;  1X27 A;  2C0O A;  1BHH A;  1AD5 A;  5J3X A;  2K79 B;  1O42 A;  4E93 A;  3BUM B;  2XP1 A;  1QCF A;  2LQW A;  1BLJ A;  2MRK A;  1O4O A;  1R1Q A;  1D4T A;  2CI9 A;  4H34 A;  1G83 A;  3VS1 A;  5EHP A;  1BKM A;  1O4K A;  2EYY A;  2ECD A;  1CSZ A;  4K11 A;  2EYZ A;  1O4D A;  1PIC A;  1HCT B;  3M7F A;  1GHU A;  4OHD A;  1QG1 E;  2BBU A;  1XA6 A;  2SHP A;  2HUW A;  1A1B A;  1OO4 A;  1O4F A;  4M4Z A;  3VGO A;  2L3T A;  5GJH A;  1AB2 A;  1A07 A;  5EHR A;  1Y1U A;  1Y57 A;  1AOT F;  3CD3 A;  2DX0 A;  1X0N A;  3GXX A;  1P13 A;  1JYU A;  4U17 A;  2DVJ A;  3GQI B;  4JGH A;  5GJI A;  3IMJ A;  3PSJ A;  4OHE A;  1WQU A;  3K2M A;  3N8M A;  4DGP A;  1FBZ A;  1O49 A;  3UYO A;  1KSW A;  1SHD A;  2KK6 A;  1X6C A;  1FHS A;  5IBS A;  4TZI A;  5HKZ A;  3CWG A;  1H9O A;  3OB1 B;  2IUI A;  3BKB A;  4JEG A;  1O4L A;  1BF5 A;  1OPK A;  4WWQ A;  1NRV A;  3VRN A;  2DLY A;  4EIH A;  3BUX B;  1B47 A;  5DF6 A;  1LUK A;  4D8K A;  2GE9 A;  2RVF A;  3KFJ A;  5EEQ A;  1A1E A;  2H5K A;  3OV1 A;  3ZNI A;  4DGX A;  5HKW A;  2EO6 A;  4X6S A;  3VRQ A;  2GSB A;  5BO4 A;  1O4A A;  1O4M A;  5DC4 A;  1LUN A;  1O4B A;  2C0T A;  4H1O A;  1BMB A;  3PS5 A;  1SKJ A;  2PNA A;  1Z3K A;  2IUG A;  3VS5 A;  1RPY A;  2FO0 A;  2MRJ A;  1FMK A;  1OO3 A;  1O4Q A;  3VRZ A;  4GPL B;  3HHM B;  1BG1 A;  2DCR A;  3IMD A;  1O4P A;  1OPL A;  2EKX A;  2Y3A B;  5I6V A;  1O48 A;  5EEL A;  1M27 A;  4OHL A;  3VS6 A;  1KA6 A;  1SPS A;  1D1Z A;  1AYD A;  4K44 A;  2EO3 A;  2ROR A;  4F5A A;  3OP0 A;  2JYQ A;  1O4N A;  2Y1M A;  2RMX A;  3PFV A;  4K45 A;  1BHH B;  4A4B A;  2LNX A;  4LUE A;  1UUR A;  2L6K A;  5AUL A;  4GWF A;  1O47 A;  2EL8 A;  1CWE A;  1SHA A;  4ROJ A;  4P9V A;  1JWO A;  3C7I A;  3BUO B;  2QMS A;  5AXI A;  1LUM A;  1BFJ A;  2CBL A;  2C9W A;  2CS0 A;  3QWY A;  1MW4 A;  2ETZ A;  1A1C A;  1R1S A;  3VRR A;  2HCK A;  3TL0 A;  1BM2 A;  4LUD A;  1JYR A;  1LKL A;  3VRY A;  1FBV A;  1GRI A;  1UUS A;  1F1W A;  3PJP A;  3UF4 A;  1O4I A;  3S9K A;  1O46 A;  1QAD A;  3EAZ A;  1NZL A;  3OB2 B;  1AYB A;  1A81 A;  2MQI A;  2CIA A;  1F2F A;  1SHB A;  1BKL A;  1RJA A;  2ABL A;  1LCK A;  2YU7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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