1BMBA

Grb2-sh2 domain in complex with kpfy*vnvef (pkf270-974)
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
98
structure length
98
Chain Sequence
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords PROTEIN (GROWTH FACTOR RECEPTOR BOUND PROTEIN 2)
total genus 23
structure length 98
sequence length 98
ec nomenclature
pdb deposition date 1998-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1bmbA00
2PNAA 1FBVA 4NWGA 2EOBA 4FL3A 1CWDL 2LNXA 3MXCA 4X6SA 3GXWA 1BLKA 4OHEA 4K44A 1O47A 2C0IA 1M27A 1O4PA 1AYCA 3S9KA 3VRYA 3VRQA 4EIHA 2K7AB 1OPLA 1CSYA 4OHIA 1LKLA 4H1OA 5IBMA 1LUKA 1O4RA 1BHHB 2DLZA 2H46E 3MAZA 4XZ0A 1JYRA 2L6KA 4F59A 4LUDA 1WQUA 1B47A 1RPYA 1F2FA 4E93A 1SKJA 3VRZA 5IBSA 1O42A 1CJ1A 2IUGA 3N84A 1AD5A 1AYBA 5GJHA 3WA4A 1NZLA 3VS1A 1X6CA 2K79B 3CBLA 2AOBA 2FCIA 1O4GA 1O4JA 3HCKA 2OQ1A 2QMSA 1O4IA 1LCJA 5J3XA 4H34A 3IN7A 1BKMA 4D8KA 2MRKA 1O4FA 3GQIB 1O49A 5EG3B 2EO6A 1NZVA 1HCSB 1FHSA 2EU0A 5AULA 3BUWB 3KFJA 5KAZA 1FU5A 1K9AA 3VRPA 3VS4A 2DX0A 1G83A 2KNOA 2HUWA 1O4AA 1OO4A 2EL8A 5HKWA 3VS7A 4OHHA 3CXLA 2DM0A 1IS0A 1H9OA 1YVHA 2RMXA 2YSXA 1LUMA 1UURA 3VROA 1P13A 1FBZA 1BLJA 1HCTB 2CBLA 1R1QA 1NRVA 2DCRA 1JU5A 3C7IA 1O41A 5EEQA 1FYRA 2CS0A 4DGPA 3VS3A 1TZEE 1MW4A 2LQWA 5DF6A 3UF4A 1GRIA 1BHHA 4K11A 4JEGA 1FU6A 2MK2A 4GWFA 2SRCA 1O44A 4OHLA 3VS2A 2IUHA 2H8HA 3HIZB 1QADA 4K2RA 2HCKA 3IN8A 1A1AA 1D4TA 2C0OA 4FL2A 2FO0A 1CWEA 5EELA 1KC2A 3PFVA 2OZOA 4TZIA 5HKYA 1SHAA 1O4LA 2HMHA 2Y3AB 5CDWA 3IMJA 2CI8A 2HDVA 4M4ZA 2PLEA 1QCFA 1A09A 3CWGA 1D1ZA 1O4OA 1QG1E 1M61A 1O4MA 1BHFA 2JYQA 2MQIA 1A81A 2L4KA 3N7YA 4XZ1A 1BFJA 3S8LA 2ABLA 5BO4A 1BFIA 4U1PA 2C9WA 2HDXA 3IMDA 1BMBA 1BG1A 3NHNA 4A4BA 1Y1UA 2MRJA 4A4CA 3GXXA 2Y1MA 1ZFPE 3VS5A 4DGXA 4WWQA 1AYDA 3VGOA 1D4WA 2CIAA 1CSZA 3N8MA 5D0JA 1LUIA 3PS5A 2LQNA 3VRNA 2EKXA 1O4DA 1XA6A 3UYOA 4GPLB 1KSWA 3EACA 2CI9A 5EHPA 1O48A 4K45A 4LUEA 3TKZA 1SPRA 1X0NA 2PNBA 4GL9E 2H5KA 3MXYA 3ZNIA 2PTKA 1I3ZA 1GHUA 1Y57A 2IZVA 1AYAA 3PSKA 4ROJA 1SHBA 4OHDA 2EYVA 1BM2A 1LKKA 2RORA 1OPKA 3HHMB 4F5BA 3S8OA 3VS6A 1TCEA 1A1CA 4EY0A 1FMKA 4JE4A 1KA7A 3TL0A 3CD3A 2SHPA 5DC0B 1A08A 2RVFA 1O43A 4P9ZA 5I6VA 1UUSA 1A1EA 5DC4A 1O45A 4F5AA 3K2MA 5HKZA 1A07A 2KK6A 1MILA 4L1BB 3US4A 2EYYA 2AOAA 4P9VA 3EAZA 3QWYA 1O4HA 5AXIA 3VRRA 3OP0A 3T04A 1R1SA 2LCTA 2EYZA 2ECDA 2LNWA 1R1PA 1SPSA 2DLYA 3PLFB 1JYQA 1JYUA 2B3OA 1O4NA 1O46A 1AOUF 4QSYA 1OO3A 1YVLA 1Z3KA 3PJPA 1AOTF 1O4BA 2GE9A 2XP1A 1O4QA 4JGHA 1O4KA 1O4EA 4U17A 1IJRA 1JWOA 2AUGA 3PSJA 4E68A 1LCKA 4FBNA 3BUOB 1LUNA 1RJAA 3S8NA 3BUXB 2BBUA 1SHDA 3OB1B 1AB2A 3QWXX 1O4CA 2GSBA 2L3TA 3OB2B 2PLDA 5GJIA 3BUNB 3BUMB 2Y1NA 2CRHA 3PQZA 1A1BA 3BKBA 1X27A 2ETZA 1KA6A 2DVJA 2IUIA 2RSYA 1BF5A 1BKLA 1RQQC 3M7FA 2MC1A 1F1WA 1PICA 2VIFA 2C0TA 5DC9A 4NWFA 3VS0A 2YU7A 5EHRA 3OV1A 3OVEA 2EO3A 2CR4A
chains in the Genus database with same CATH superfamily
2PNAA 1FBVA 4NWGA 2EOBA 4FL3A 1CWDL 2LNXA 3MXCA 4X6SA 3GXWA 1BLKA 4OHEA 4K44A 1O47A 2C0IA 1M27A 1O4PA 1AYCA 3S9KA 3VRYA 3VRQA 4EIHA 2K7AB 1OPLA 1CSYA 4OHIA 1LKLA 4H1OA 5IBMA 1LUKA 1O4RA 1BHHB 2DLZA 2H46E 3MAZA 4XZ0A 1JYRA 2L6KA 4F59A 4LUDA 1WQUA 1B47A 1RPYA 1F2FA 4E93A 1SKJA 3VRZA 5IBSA 1O42A 1CJ1A 2IUGA 3N84A 1AD5A 1AYBA 5GJHA 3WA4A 1NZLA 3VS1A 1X6CA 2K79B 3CBLA 2AOBA 2FCIA 1O4GA 1O4JA 3HCKA 2OQ1A 2QMSA 1O4IA 1LCJA 5J3XA 4H34A 3IN7A 1BKMA 4D8KA 2MRKA 1O4FA 3GQIB 1O49A 5EG3B 2EO6A 1NZVA 1HCSB 1FHSA 2EU0A 5AULA 3BUWB 3KFJA 5KAZA 1FU5A 1K9AA 3VRPA 3VS4A 2DX0A 1G83A 2KNOA 2HUWA 1O4AA 1OO4A 2EL8A 5HKWA 3VS7A 4OHHA 3CXLA 2DM0A 1IS0A 1H9OA 1YVHA 2RMXA 2YSXA 1LUMA 1UURA 3VROA 1P13A 1FBZA 1BLJA 1HCTB 2CBLA 1R1QA 1NRVA 2DCRA 1JU5A 3C7IA 1O41A 5EEQA 1FYRA 2CS0A 4DGPA 3VS3A 1TZEE 1MW4A 2LQWA 5DF6A 3UF4A 1GRIA 1BHHA 4K11A 4JEGA 1FU6A 2MK2A 4GWFA 2SRCA 1O44A 4OHLA 3VS2A 2IUHA 2H8HA 3HIZB 1QADA 4K2RA 2HCKA 3IN8A 1A1AA 1D4TA 2C0OA 4FL2A 2FO0A 1CWEA 5EELA 1KC2A 3PFVA 2OZOA 4TZIA 5HKYA 1SHAA 1O4LA 2HMHA 2Y3AB 5CDWA 3IMJA 2CI8A 2HDVA 4M4ZA 2PLEA 1QCFA 1A09A 3CWGA 1D1ZA 1O4OA 1QG1E 1M61A 2KGYA 1O4MA 1BHFA 2JYQA 2MQIA 1A81A 2L4KA 3LYVA 3N7YA 4XZ1A 1BFJA 3S8LA 2ABLA 5BO4A 1BFIA 4U1PA 2C9WA 2HDXA 3IMDA 1BMBA 1BG1A 3NHNA 4A4BA 1Y1UA 2MRJA 4A4CA 3GXXA 2Y1MA 1ZFPE 3VS5A 4DGXA 4WWQA 1AYDA 3VGOA 1D4WA 2LRAA 2CIAA 1CSZA 3K2TA 3N8MA 5D0JA 1LUIA 3PS5A 2LQNA 3VRNA 2EKXA 1O4DA 1XA6A 3UYOA 4GPLB 1KSWA 3EACA 2CI9A 5EHPA 1O48A 4K45A 4LUEA 3TKZA 1SPRA 1X0NA 2PNBA 4GL9E 2H5KA 3MXYA 3ZNIA 2PTKA 1I3ZA 1GHUA 1Y57A 2IZVA 1AYAA 3PSKA 4ROJA 1SHBA 4OHDA 2EYVA 1BM2A 1LKKA 2RORA 1OPKA 3HHMB 4F5BA 3S8OA 3VS6A 1TCEA 1A1CA 4EY0A 1FMKA 4JE4A 1KA7A 3TL0A 3CD3A 2SHPA 5DC0B 1A08A 2RVFA 1O43A 4P9ZA 5I6VA 1UUSA 1A1EA 5DC4A 1O45A 4F5AA 3K2MA 5HKZA 1A07A 2KK6A 1MILA 4L1BB 3US4A 2EYYA 2AOAA 4P9VA 3EAZA 3QWYA 1O4HA 5AXIA 3VRRA 3OP0A 3T04A 1R1SA 2LCTA 2EYZA 2ECDA 2LNWA 1R1PA 1SPSA 2DLYA 3PLFB 1JYQA 1JYUA 2B3OA 1O4NA 1O46A 1AOUF 4QSYA 1OO3A 1YVLA 1Z3KA 3PJPA 1AOTF 1O4BA 2GE9A 2XP1A 1O4QA 4JGHA 1O4KA 1O4EA 4U17A 1IJRA 1JWOA 2AUGA 3PSJA 4E68A 1LCKA 4FBNA 3BUOB 1LUNA 1RJAA 3S8NA 3BUXB 2BBUA 1SHDA 3OB1B 1AB2A 3QWXX 1O4CA 2GSBA 2L3TA 3OB2B 2PLDA 5GJIA 3BUNB 3BUMB 2Y1NA 2CRHA 3PQZA 1A1BA 3BKBA 1X27A 2ETZA 1KA6A 2DVJA 2IUIA 2RSYA 1BF5A 1BKLA 1RQQC 3M7FA 2MC1A 1F1WA 1PICA 2VIFA 2C0TA 5DC9A 4NWFA 3VS0A 2YU7A 5EHRA 3OV1A 3OVEA 2EO3A 2CR4A
chains in the Genus database with same CATH topology
2PNAA 1FBVA 4NWGA 2EOBA 4FL3A 1CWDL 2LNXA 3MXCA 4X6SA 3GXWA 1BLKA 4OHEA 4K44A 1O47A 2C0IA 1M27A 1O4PA 1AYCA 3S9KA 3VRYA 3VRQA 4EIHA 2K7AB 1OPLA 1CSYA 4OHIA 1LKLA 4H1OA 5IBMA 1LUKA 1O4RA 1BHHB 2DLZA 2H46E 3MAZA 4XZ0A 1JYRA 2L6KA 4F59A 4LUDA 1WQUA 1B47A 1RPYA 1F2FA 4E93A 1SKJA 3VRZA 5IBSA 1O42A 1CJ1A 2IUGA 3N84A 1AD5A 1AYBA 5GJHA 3WA4A 1NZLA 3VS1A 1X6CA 2K79B 3CBLA 2AOBA 2FCIA 1O4GA 1O4JA 3HCKA 2OQ1A 2QMSA 1O4IA 1LCJA 5J3XA 4H34A 3IN7A 1BKMA 4D8KA 2MRKA 1O4FA 3GQIB 1O49A 5EG3B 2EO6A 1NZVA 1HCSB 1FHSA 2EU0A 5AULA 3BUWB 3KFJA 5KAZA 1FU5A 1K9AA 3VRPA 3VS4A 2DX0A 1G83A 2KNOA 2HUWA 1O4AA 1OO4A 2EL8A 5HKWA 3VS7A 4OHHA 3CXLA 2DM0A 1IS0A 1H9OA 1YVHA 2RMXA 2YSXA 1LUMA 1UURA 3VROA 1P13A 1FBZA 1BLJA 1HCTB 2CBLA 1R1QA 1NRVA 2DCRA 1JU5A 3C7IA 1O41A 5EEQA 1FYRA 2CS0A 4DGPA 3VS3A 1TZEE 1MW4A 2LQWA 5DF6A 3UF4A 1GRIA 1BHHA 4K11A 4JEGA 1FU6A 2MK2A 4GWFA 2SRCA 1O44A 4OHLA 3VS2A 2IUHA 2H8HA 3HIZB 1QADA 4K2RA 2HCKA 3IN8A 1A1AA 1D4TA 2C0OA 4FL2A 2FO0A 1CWEA 5EELA 1KC2A 3PFVA 2OZOA 4TZIA 5HKYA 1SHAA 1O4LA 2HMHA 2Y3AB 5CDWA 3IMJA 2CI8A 2HDVA 4M4ZA 2PLEA 1QCFA 1A09A 3CWGA 1D1ZA 1O4OA 1QG1E 1M61A 1O4MA 1BHFA 2JYQA 2MQIA 1A81A 2L4KA 3N7YA 4XZ1A 1BFJA 3S8LA 2ABLA 5BO4A 1BFIA 4U1PA 2C9WA 2HDXA 3IMDA 1BMBA 1BG1A 3NHNA 4A4BA 1Y1UA 2MRJA 4A4CA 3GXXA 2Y1MA 1ZFPE 3VS5A 4DGXA 4WWQA 1AYDA 3VGOA 1D4WA 2CIAA 1CSZA 3N8MA 5D0JA 1LUIA 3PS5A 2LQNA 3VRNA 2EKXA 1O4DA 1XA6A 3UYOA 4GPLB 1KSWA 3EACA 2CI9A 5EHPA 1O48A 4K45A 4LUEA 3TKZA 1SPRA 1X0NA 2PNBA 4GL9E 2H5KA 3MXYA 3ZNIA 2PTKA 1I3ZA 1GHUA 1Y57A 2IZVA 1AYAA 3PSKA 4ROJA 1SHBA 4OHDA 2EYVA 1BM2A 1LKKA 2RORA 1OPKA 3HHMB 4F5BA 3S8OA 3VS6A 1TCEA 1A1CA 4EY0A 1FMKA 4JE4A 1KA7A 3TL0A 3CD3A 2SHPA 5DC0B 1A08A 2RVFA 1O43A 4P9ZA 5I6VA 1UUSA 1A1EA 5DC4A 1O45A 4F5AA 3K2MA 5HKZA 1A07A 2KK6A 1MILA 4L1BB 3US4A 2EYYA 2AOAA 4P9VA 3EAZA 3QWYA 1O4HA 5AXIA 3VRRA 3OP0A 3T04A 1R1SA 2LCTA 2EYZA 2ECDA 2LNWA 1R1PA 1SPSA 2DLYA 3PLFB 1JYQA 1JYUA 2B3OA 1O4NA 1O46A 1AOUF 4QSYA 1OO3A 1YVLA 1Z3KA 3PJPA 1AOTF 1O4BA 2GE9A 2XP1A 1O4QA 4JGHA 1O4KA 1O4EA 4U17A 1IJRA 1JWOA 2AUGA 3PSJA 4E68A 1LCKA 4FBNA 3BUOB 1LUNA 1RJAA 3S8NA 3BUXB 2BBUA 1SHDA 3OB1B 1AB2A 3QWXX 1O4CA 2GSBA 2L3TA 3OB2B 2PLDA 5GJIA 3BUNB 3BUMB 2Y1NA 2CRHA 3PQZA 1A1BA 3BKBA 1X27A 2ETZA 1KA6A 2DVJA 2IUIA 2RSYA 1BF5A 1BKLA 1RQQC 3M7FA 2MC1A 1F1WA 1PICA 2VIFA 2C0TA 5DC9A 4NWFA 3VS0A 2YU7A 5EHRA 3OV1A 3OVEA 2EO3A 2CR4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PNA A;  1FBV A;  4NWG A;  2EOB A;  4FL3 A;  1CWD L;  2LNX A;  3MXC A;  4X6S A;  3GXW A;  1BLK A;  4OHE A;  4K44 A;  1O47 A;  2C0I A;  1M27 A;  1O4P A;  1AYC A;  3S9K A;  3VRY A;  3VRQ A;  4EIH A;  2K7A B;  1OPL A;  1CSY A;  4OHI A;  1LKL A;  4H1O A;  5IBM A;  1LUK A;  1O4R A;  1BHH B;  2DLZ A;  2H46 E;  3MAZ A;  4XZ0 A;  1JYR A;  2L6K A;  4F59 A;  4LUD A;  1WQU A;  1B47 A;  1RPY A;  1F2F A;  4E93 A;  1SKJ A;  3VRZ A;  5IBS A;  1O42 A;  1CJ1 A;  2IUG A;  3N84 A;  1AD5 A;  1AYB A;  5GJH A;  3WA4 A;  1NZL A;  3VS1 A;  1X6C A;  2K79 B;  3CBL A;  2AOB A;  2FCI A;  1O4G A;  1O4J A;  3HCK A;  2OQ1 A;  2QMS A;  1O4I A;  1LCJ A;  5J3X A;  4H34 A;  3IN7 A;  1BKM A;  4D8K A;  2MRK A;  1O4F A;  3GQI B;  1O49 A;  5EG3 B;  2EO6 A;  1NZV A;  1HCS B;  1FHS A;  2EU0 A;  5AUL A;  3BUW B;  3KFJ A;  5KAZ A;  1FU5 A;  1K9A A;  3VRP A;  3VS4 A;  2DX0 A;  1G83 A;  2KNO A;  2HUW A;  1O4A A;  1OO4 A;  2EL8 A;  5HKW A;  3VS7 A;  4OHH A;  3CXL A;  2DM0 A;  1IS0 A;  1H9O A;  1YVH A;  2RMX A;  2YSX A;  1LUM A;  1UUR A;  3VRO A;  1P13 A;  1FBZ A;  1BLJ A;  1HCT B;  2CBL A;  1R1Q A;  1NRV A;  2DCR A;  1JU5 A;  3C7I A;  1O41 A;  5EEQ A;  1FYR A;  2CS0 A;  4DGP A;  3VS3 A;  1TZE E;  1MW4 A;  2LQW A;  5DF6 A;  3UF4 A;  1GRI A;  1BHH A;  4K11 A;  4JEG A;  1FU6 A;  2MK2 A;  4GWF A;  2SRC A;  1O44 A;  4OHL A;  3VS2 A;  2IUH A;  2H8H A;  3HIZ B;  1QAD A;  4K2R A;  2HCK A;  3IN8 A;  1A1A A;  1D4T A;  2C0O A;  4FL2 A;  2FO0 A;  1CWE A;  5EEL A;  1KC2 A;  3PFV A;  2OZO A;  4TZI A;  5HKY A;  1SHA A;  1O4L A;  2HMH A;  2Y3A B;  5CDW A;  3IMJ A;  2CI8 A;  2HDV A;  4M4Z A;  2PLE A;  1QCF A;  1A09 A;  3CWG A;  1D1Z A;  1O4O A;  1QG1 E;  1M61 A;  1O4M A;  1BHF A;  2JYQ A;  2MQI A;  1A81 A;  2L4K A;  3N7Y A;  4XZ1 A;  1BFJ A;  3S8L A;  2ABL A;  5BO4 A;  1BFI A;  4U1P A;  2C9W A;  2HDX A;  3IMD A;  1BMB A;  1BG1 A;  3NHN A;  4A4B A;  1Y1U A;  2MRJ A;  4A4C A;  3GXX A;  2Y1M A;  1ZFP E;  3VS5 A;  4DGX A;  4WWQ A;  1AYD A;  3VGO A;  1D4W A;  2CIA A;  1CSZ A;  3N8M A;  5D0J A;  1LUI A;  3PS5 A;  2LQN A;  3VRN A;  2EKX A;  1O4D A;  1XA6 A;  3UYO A;  4GPL B;  1KSW A;  3EAC A;  2CI9 A;  5EHP A;  1O48 A;  4K45 A;  4LUE A;  3TKZ A;  1SPR A;  1X0N A;  2PNB A;  4GL9 E;  2H5K A;  3MXY A;  3ZNI A;  2PTK A;  1I3Z A;  1GHU A;  1Y57 A;  2IZV A;  1AYA A;  3PSK A;  4ROJ A;  1SHB A;  4OHD A;  2EYV A;  1BM2 A;  1LKK A;  2ROR A;  1OPK A;  3HHM B;  4F5B A;  3S8O A;  3VS6 A;  1TCE A;  1A1C A;  4EY0 A;  1FMK A;  4JE4 A;  1KA7 A;  3TL0 A;  3CD3 A;  2SHP A;  5DC0 B;  1A08 A;  2RVF A;  1O43 A;  4P9Z A;  5I6V A;  1UUS A;  1A1E A;  5DC4 A;  1O45 A;  4F5A A;  3K2M A;  5HKZ A;  1A07 A;  2KK6 A;  1MIL A;  4L1B B;  3US4 A;  2EYY A;  2AOA A;  4P9V A;  3EAZ A;  3QWY A;  1O4H A;  5AXI A;  3VRR A;  3OP0 A;  3T04 A;  1R1S A;  2LCT A;  2EYZ A;  2ECD A;  2LNW A;  1R1P A;  1SPS A;  2DLY A;  3PLF B;  1JYQ A;  1JYU A;  2B3O A;  1O4N A;  1O46 A;  1AOU F;  4QSY A;  1OO3 A;  1YVL A;  1Z3K A;  3PJP A;  1AOT F;  1O4B A;  2GE9 A;  2XP1 A;  1O4Q A;  4JGH A;  1O4K A;  1O4E A;  4U17 A;  1IJR A;  1JWO A;  2AUG A;  3PSJ A;  4E68 A;  1LCK A;  4FBN A;  3BUO B;  1LUN A;  1RJA A;  3S8N A;  3BUX B;  2BBU A;  1SHD A;  3OB1 B;  1AB2 A;  3QWX X;  1O4C A;  2GSB A;  2L3T A;  3OB2 B;  2PLD A;  5GJI A;  3BUN B;  3BUM B;  2Y1N A;  2CRH A;  3PQZ A;  1A1B A;  3BKB A;  1X27 A;  2ETZ A;  1KA6 A;  2DVJ A;  2IUI A;  2RSY A;  1BF5 A;  1BKL A;  1RQQ C;  3M7F A;  2MC1 A;  1F1W A;  1PIC A;  2VIF A;  2C0T A;  5DC9 A;  4NWF A;  3VS0 A;  2YU7 A;  5EHR A;  3OV1 A;  3OVE A;  2EO3 A;  2CR4 A; 
#chains in the Genus database with same CATH topology
 2PNA A;  1FBV A;  4NWG A;  2EOB A;  4FL3 A;  1CWD L;  2LNX A;  3MXC A;  4X6S A;  3GXW A;  1BLK A;  4OHE A;  4K44 A;  1O47 A;  2C0I A;  1M27 A;  1O4P A;  1AYC A;  3S9K A;  3VRY A;  3VRQ A;  4EIH A;  2K7A B;  1OPL A;  1CSY A;  4OHI A;  1LKL A;  4H1O A;  5IBM A;  1LUK A;  1O4R A;  1BHH B;  2DLZ A;  2H46 E;  3MAZ A;  4XZ0 A;  1JYR A;  2L6K A;  4F59 A;  4LUD A;  1WQU A;  1B47 A;  1RPY A;  1F2F A;  4E93 A;  1SKJ A;  3VRZ A;  5IBS A;  1O42 A;  1CJ1 A;  2IUG A;  3N84 A;  1AD5 A;  1AYB A;  5GJH A;  3WA4 A;  1NZL A;  3VS1 A;  1X6C A;  2K79 B;  3CBL A;  2AOB A;  2FCI A;  1O4G A;  1O4J A;  3HCK A;  2OQ1 A;  2QMS A;  1O4I A;  1LCJ A;  5J3X A;  4H34 A;  3IN7 A;  1BKM A;  4D8K A;  2MRK A;  1O4F A;  3GQI B;  1O49 A;  5EG3 B;  2EO6 A;  1NZV A;  1HCS B;  1FHS A;  2EU0 A;  5AUL A;  3BUW B;  3KFJ A;  5KAZ A;  1FU5 A;  1K9A A;  3VRP A;  3VS4 A;  2DX0 A;  1G83 A;  2KNO A;  2HUW A;  1O4A A;  1OO4 A;  2EL8 A;  5HKW A;  3VS7 A;  4OHH A;  3CXL A;  2DM0 A;  1IS0 A;  1H9O A;  1YVH A;  2RMX A;  2YSX A;  1LUM A;  1UUR A;  3VRO A;  1P13 A;  1FBZ A;  1BLJ A;  1HCT B;  2CBL A;  1R1Q A;  1NRV A;  2DCR A;  1JU5 A;  3C7I A;  1O41 A;  5EEQ A;  1FYR A;  2CS0 A;  4DGP A;  3VS3 A;  1TZE E;  1MW4 A;  2LQW A;  5DF6 A;  3UF4 A;  1GRI A;  1BHH A;  4K11 A;  4JEG A;  1FU6 A;  2MK2 A;  4GWF A;  2SRC A;  1O44 A;  4OHL A;  3VS2 A;  2IUH A;  2H8H A;  3HIZ B;  1QAD A;  4K2R A;  2HCK A;  3IN8 A;  1A1A A;  1D4T A;  2C0O A;  4FL2 A;  2FO0 A;  1CWE A;  5EEL A;  1KC2 A;  3PFV A;  2OZO A;  4TZI A;  5HKY A;  1SHA A;  1O4L A;  2HMH A;  2Y3A B;  5CDW A;  3IMJ A;  2CI8 A;  2HDV A;  4M4Z A;  2PLE A;  1QCF A;  1A09 A;  3CWG A;  1D1Z A;  1O4O A;  1QG1 E;  1M61 A;  2KGY A;  1O4M A;  1BHF A;  2JYQ A;  2MQI A;  1A81 A;  2L4K A;  3LYV A;  3N7Y A;  4XZ1 A;  1BFJ A;  3S8L A;  2ABL A;  5BO4 A;  1BFI A;  4U1P A;  2C9W A;  2HDX A;  3IMD A;  1BMB A;  1BG1 A;  3NHN A;  4A4B A;  1Y1U A;  2MRJ A;  4A4C A;  3GXX A;  2Y1M A;  1ZFP E;  3VS5 A;  4DGX A;  4WWQ A;  1AYD A;  3VGO A;  1D4W A;  2LRA A;  2CIA A;  1CSZ A;  3K2T A;  3N8M A;  5D0J A;  1LUI A;  3PS5 A;  2LQN A;  3VRN A;  2EKX A;  1O4D A;  1XA6 A;  3UYO A;  4GPL B;  1KSW A;  3EAC A;  2CI9 A;  5EHP A;  1O48 A;  4K45 A;  4LUE A;  3TKZ A;  1SPR A;  1X0N A;  2PNB A;  4GL9 E;  2H5K A;  3MXY A;  3ZNI A;  2PTK A;  1I3Z A;  1GHU A;  1Y57 A;  2IZV A;  1AYA A;  3PSK A;  4ROJ A;  1SHB A;  4OHD A;  2EYV A;  1BM2 A;  1LKK A;  2ROR A;  1OPK A;  3HHM B;  4F5B A;  3S8O A;  3VS6 A;  1TCE A;  1A1C A;  4EY0 A;  1FMK A;  4JE4 A;  1KA7 A;  3TL0 A;  3CD3 A;  2SHP A;  5DC0 B;  1A08 A;  2RVF A;  1O43 A;  4P9Z A;  5I6V A;  1UUS A;  1A1E A;  5DC4 A;  1O45 A;  4F5A A;  3K2M A;  5HKZ A;  1A07 A;  2KK6 A;  1MIL A;  4L1B B;  3US4 A;  2EYY A;  2AOA A;  4P9V A;  3EAZ A;  3QWY A;  1O4H A;  5AXI A;  3VRR A;  3OP0 A;  3T04 A;  1R1S A;  2LCT A;  2EYZ A;  2ECD A;  2LNW A;  1R1P A;  1SPS A;  2DLY A;  3PLF B;  1JYQ A;  1JYU A;  2B3O A;  1O4N A;  1O46 A;  1AOU F;  4QSY A;  1OO3 A;  1YVL A;  1Z3K A;  3PJP A;  1AOT F;  1O4B A;  2GE9 A;  2XP1 A;  1O4Q A;  4JGH A;  1O4K A;  1O4E A;  4U17 A;  1IJR A;  1JWO A;  2AUG A;  3PSJ A;  4E68 A;  1LCK A;  4FBN A;  3BUO B;  1LUN A;  1RJA A;  3S8N A;  3BUX B;  2BBU A;  1SHD A;  3OB1 B;  1AB2 A;  3QWX X;  1O4C A;  2GSB A;  2L3T A;  3OB2 B;  2PLD A;  5GJI A;  3BUN B;  3BUM B;  2Y1N A;  2CRH A;  3PQZ A;  1A1B A;  3BKB A;  1X27 A;  2ETZ A;  1KA6 A;  2DVJ A;  2IUI A;  2RSY A;  1BF5 A;  1BKL A;  1RQQ C;  3M7F A;  2MC1 A;  1F1W A;  1PIC A;  2VIF A;  2C0T A;  5DC9 A;  4NWF A;  3VS0 A;  2YU7 A;  5EHR A;  3OV1 A;  3OVE A;  2EO3 A;  2CR4 A; 
#chains in the Genus database with same CATH homology
 2PNA A;  1FBV A;  4NWG A;  2EOB A;  4FL3 A;  1CWD L;  2LNX A;  3MXC A;  4X6S A;  3GXW A;  1BLK A;  4OHE A;  4K44 A;  1O47 A;  2C0I A;  1M27 A;  1O4P A;  1AYC A;  3S9K A;  3VRY A;  3VRQ A;  4EIH A;  2K7A B;  1OPL A;  1CSY A;  4OHI A;  1LKL A;  4H1O A;  5IBM A;  1LUK A;  1O4R A;  1BHH B;  2DLZ A;  2H46 E;  3MAZ A;  4XZ0 A;  1JYR A;  2L6K A;  4F59 A;  4LUD A;  1WQU A;  1B47 A;  1RPY A;  1F2F A;  4E93 A;  1SKJ A;  3VRZ A;  5IBS A;  1O42 A;  1CJ1 A;  2IUG A;  3N84 A;  1AD5 A;  1AYB A;  5GJH A;  3WA4 A;  1NZL A;  3VS1 A;  1X6C A;  2K79 B;  3CBL A;  2AOB A;  2FCI A;  1O4G A;  1O4J A;  3HCK A;  2OQ1 A;  2QMS A;  1O4I A;  1LCJ A;  5J3X A;  4H34 A;  3IN7 A;  1BKM A;  4D8K A;  2MRK A;  1O4F A;  3GQI B;  1O49 A;  5EG3 B;  2EO6 A;  1NZV A;  1HCS B;  1FHS A;  2EU0 A;  5AUL A;  3BUW B;  3KFJ A;  5KAZ A;  1FU5 A;  1K9A A;  3VRP A;  3VS4 A;  2DX0 A;  1G83 A;  2KNO A;  2HUW A;  1O4A A;  1OO4 A;  2EL8 A;  5HKW A;  3VS7 A;  4OHH A;  3CXL A;  2DM0 A;  1IS0 A;  1H9O A;  1YVH A;  2RMX A;  2YSX A;  1LUM A;  1UUR A;  3VRO A;  1P13 A;  1FBZ A;  1BLJ A;  1HCT B;  2CBL A;  1R1Q A;  1NRV A;  2DCR A;  1JU5 A;  3C7I A;  1O41 A;  5EEQ A;  1FYR A;  2CS0 A;  4DGP A;  3VS3 A;  1TZE E;  1MW4 A;  2LQW A;  5DF6 A;  3UF4 A;  1GRI A;  1BHH A;  4K11 A;  4JEG A;  1FU6 A;  2MK2 A;  4GWF A;  2SRC A;  1O44 A;  4OHL A;  3VS2 A;  2IUH A;  2H8H A;  3HIZ B;  1QAD A;  4K2R A;  2HCK A;  3IN8 A;  1A1A A;  1D4T A;  2C0O A;  4FL2 A;  2FO0 A;  1CWE A;  5EEL A;  1KC2 A;  3PFV A;  2OZO A;  4TZI A;  5HKY A;  1SHA A;  1O4L A;  2HMH A;  2Y3A B;  5CDW A;  3IMJ A;  2CI8 A;  2HDV A;  4M4Z A;  2PLE A;  1QCF A;  1A09 A;  3CWG A;  1D1Z A;  1O4O A;  1QG1 E;  1M61 A;  1O4M A;  1BHF A;  2JYQ A;  2MQI A;  1A81 A;  2L4K A;  3N7Y A;  4XZ1 A;  1BFJ A;  3S8L A;  2ABL A;  5BO4 A;  1BFI A;  4U1P A;  2C9W A;  2HDX A;  3IMD A;  1BMB A;  1BG1 A;  3NHN A;  4A4B A;  1Y1U A;  2MRJ A;  4A4C A;  3GXX A;  2Y1M A;  1ZFP E;  3VS5 A;  4DGX A;  4WWQ A;  1AYD A;  3VGO A;  1D4W A;  2CIA A;  1CSZ A;  3N8M A;  5D0J A;  1LUI A;  3PS5 A;  2LQN A;  3VRN A;  2EKX A;  1O4D A;  1XA6 A;  3UYO A;  4GPL B;  1KSW A;  3EAC A;  2CI9 A;  5EHP A;  1O48 A;  4K45 A;  4LUE A;  3TKZ A;  1SPR A;  1X0N A;  2PNB A;  4GL9 E;  2H5K A;  3MXY A;  3ZNI A;  2PTK A;  1I3Z A;  1GHU A;  1Y57 A;  2IZV A;  1AYA A;  3PSK A;  4ROJ A;  1SHB A;  4OHD A;  2EYV A;  1BM2 A;  1LKK A;  2ROR A;  1OPK A;  3HHM B;  4F5B A;  3S8O A;  3VS6 A;  1TCE A;  1A1C A;  4EY0 A;  1FMK A;  4JE4 A;  1KA7 A;  3TL0 A;  3CD3 A;  2SHP A;  5DC0 B;  1A08 A;  2RVF A;  1O43 A;  4P9Z A;  5I6V A;  1UUS A;  1A1E A;  5DC4 A;  1O45 A;  4F5A A;  3K2M A;  5HKZ A;  1A07 A;  2KK6 A;  1MIL A;  4L1B B;  3US4 A;  2EYY A;  2AOA A;  4P9V A;  3EAZ A;  3QWY A;  1O4H A;  5AXI A;  3VRR A;  3OP0 A;  3T04 A;  1R1S A;  2LCT A;  2EYZ A;  2ECD A;  2LNW A;  1R1P A;  1SPS A;  2DLY A;  3PLF B;  1JYQ A;  1JYU A;  2B3O A;  1O4N A;  1O46 A;  1AOU F;  4QSY A;  1OO3 A;  1YVL A;  1Z3K A;  3PJP A;  1AOT F;  1O4B A;  2GE9 A;  2XP1 A;  1O4Q A;  4JGH A;  1O4K A;  1O4E A;  4U17 A;  1IJR A;  1JWO A;  2AUG A;  3PSJ A;  4E68 A;  1LCK A;  4FBN A;  3BUO B;  1LUN A;  1RJA A;  3S8N A;  3BUX B;  2BBU A;  1SHD A;  3OB1 B;  1AB2 A;  3QWX X;  1O4C A;  2GSB A;  2L3T A;  3OB2 B;  2PLD A;  5GJI A;  3BUN B;  3BUM B;  2Y1N A;  2CRH A;  3PQZ A;  1A1B A;  3BKB A;  1X27 A;  2ETZ A;  1KA6 A;  2DVJ A;  2IUI A;  2RSY A;  1BF5 A;  1BKL A;  1RQQ C;  3M7F A;  2MC1 A;  1F1W A;  1PIC A;  2VIF A;  2C0T A;  5DC9 A;  4NWF A;  3VS0 A;  2YU7 A;  5EHR A;  3OV1 A;  3OVE A;  2EO3 A;  2CR4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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