1FYRA

Dimer formation through domain swapping in the crystal structure of the grb2-sh2 ac-pyvnv complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
95
structure length
95
Chain Sequence
HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
total genus 20
structure length 95
sequence length 95
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2000-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1fyrA00
5KAZA 3WA4A 2CBLA 4E93A 4LUEA 1YVLA 3MAZA 1O43A 3VS2A 3VS4A 4F59A 5EEQA 5IBMA 3PLFB 1A1BA 1FHSA 2DM0A 1LKKA 3C7IA 2LNXA 1I3ZA 4P9VA 1TZEE 2PNBA 1FBZA 3MXCA 2YSXA 5DC0B 5IBSA 1KC2A 1FYRA 3T04A 2BBUA 4X6SA 2QMSA 4JE4A 3VROA 1O42A 1CSZA 1LUIA 2PTKA 3EACA 1KA6A 2H5KA 1AYCA 3US4A 4GPLB 3HHMB 2HDXA 4OHDA 3EAZA 5GJIA 2EYVA 4H1OA 2HUWA 1HCSB 4WWQA 2EO6A 1BFIA 1BMBA 4U17A 2ABLA 1OPLA 5AULA 1NZLA 4GL9E 2IUIA 1K9AA 2L4KA 1BFJA 3VRPA 4DGPA 4NWFA 4ROJA 3VS0A 1BKLA 4JEGA 1QG1E 5EG3B 4OHHA 3CWGA 1AYBA 1SKJA 2SRCA 2L6KA 1O48A 1FU6A 1RJAA 1LUMA 2K79B 1O4MA 1GRIA 1SHBA 1AYAA 3S8OA 2CI8A 2C9WA 2PLEA 1OPKA 5EELA 1R1PA 1UUSA 1JYQA 3VS7A 2EKXA 2IUGA 3N8MA 5J3XA 5BO4A 1O4LA 4F5AA 5D0JA 2DLZA 2H8HA 2MQIA 4FL3A 1OO3A 4FL2A 1H9OA 1O45A 1M61A 1RPYA 1R1QA 3IMJA 1JU5A 3KFJA 3VRQA 1P13A 1G83A 1PICA 2PLDA 1Y57A 1O41A 5CDWA 1CWDL 5DC9A 3MXYA 5GJHA 1BKMA 1QCFA 2MRJA 2YU7A 2RSYA 2MC1A 1OO4A 2C0OA 1O46A 3K2MA 3VS6A 1BHFA 3S8NA 1JYRA 1O4CA 3OB1B 1BLJA 3S8LA 1XA6A 2EL8A 1QADA 4K2RA 2AUGA 1SHAA 1X27A 1LUKA 1O4EA 1NZVA 1LCJA 1AOUF 4QSYA 4OHEA 3OP0A 1WQUA 1O4QA 2Y3AB 4K45A 3IN8A 2HMHA 3GXWA 2HCKA 1F2FA 5DF6A 5EHPA 2SHPA 1O4OA 3GQIB 1BHHB 3QWXX 2C0TA 3NHNA 4XZ1A 1O47A 5AXIA 2PNAA 3UF4A 1HCTB 3TKZA 2EOBA 1NRVA 1JYUA 2LQNA 1A1AA 5HKYA 1Z3KA 3OVEA 2AOAA 3BUXB 1BM2A 4A4CA 1IS0A 3OV1A 1FMKA 2ECDA 2VIFA 3BUWB 2Y1MA 4F5BA 1A08A 1YVHA 2EYYA 2RORA 2CIAA 1AOTF 2CR4A 2KNOA 2CI9A 3CD3A 1O4JA 1R1SA 1O4AA 2LQWA 1O4NA 1BLKA 5EHRA 2GSBA 3PSJA 3HIZB 1D1ZA 3PS5A 1F1WA 3N84A 4E68A 5HKZA 1AB2A 2IZVA 4JGHA 4TZIA 1SPSA 1BF5A 1X6CA 2EU0A 2HDVA 2RMXA 1SPRA 1LKLA 1A09A 1M27A 3PQZA 1O4KA 1B47A 2ETZA 1SHDA 1AYDA 2H46E 4A4BA 2DVJA 2XP1A 4K11A 1IJRA 1UURA 2FCIA 3HCKA 4P9ZA 1A1CA 1CSYA 5I6VA 2RVFA 3PSKA 3IN7A 3VRZA 3PFVA 1A07A 4NWGA 1LUNA 4EIHA 4D8KA 1KA7A 2L3TA 1TCEA 3VS1A 3UYOA 3BUMB 2DLYA 3ZNIA 4M4ZA 2B3OA 1CJ1A 1O4DA 3IMDA 1RQQC 3OB2B 1FBVA 3VRYA 4GWFA 2OZOA 1O4IA 1LCKA 1GHUA 2JYQA 1CWEA 2C0IA 1O4FA 2AOBA 3N7YA 2FO0A 3VS5A 2CS0A 1MILA 3S9KA 2GE9A 2EO3A 1JWOA 1O4GA 2DX0A 3BKBA 1A1EA 1O4RA 1ZFPE 3CXLA 3VS3A 3M7FA 2LNWA 1X0NA 4FBNA 4OHIA 1O49A 2MRKA 2KK6A 4EY0A 1O44A 3VGOA 2OQ1A 1FU5A 4OHLA 4LUDA 1O4PA 2CRHA 3VRRA 1O4HA 3TL0A 1Y1UA 1KSWA 4K44A 4L1BB 5DC4A 2K7AB 1O4BA 1A81A 4U1PA 3BUOB 3BUNB 4H34A 2EYZA 3QWYA 1AD5A 1BG1A 3GXXA 3VRNA 2LCTA 1D4WA 1D4TA 5HKWA 2IUHA 1MW4A 4XZ0A 2MK2A 1BHHA 4DGXA 3CBLA 3PJPA 2DCRA 2Y1NA
chains in the Genus database with same CATH superfamily
5KAZA 3WA4A 2CBLA 4E93A 4LUEA 1YVLA 3MAZA 1O43A 3VS2A 3VS4A 4F59A 5EEQA 5IBMA 3PLFB 1A1BA 1FHSA 2DM0A 1LKKA 3C7IA 2LNXA 1I3ZA 4P9VA 1TZEE 2PNBA 1FBZA 3MXCA 2YSXA 5DC0B 5IBSA 1KC2A 1FYRA 3T04A 2BBUA 4X6SA 2QMSA 4JE4A 3VROA 1O42A 1CSZA 1LUIA 2PTKA 3EACA 1KA6A 2H5KA 1AYCA 3US4A 4GPLB 3HHMB 2HDXA 4OHDA 3EAZA 5GJIA 2EYVA 4H1OA 2HUWA 1HCSB 4WWQA 2EO6A 1BFIA 1BMBA 4U17A 2ABLA 1OPLA 5AULA 1NZLA 4GL9E 2IUIA 1K9AA 2L4KA 1BFJA 3VRPA 4DGPA 4NWFA 4ROJA 3VS0A 1BKLA 4JEGA 1QG1E 5EG3B 4OHHA 3CWGA 1AYBA 1SKJA 2SRCA 2L6KA 1O48A 1FU6A 1RJAA 1LUMA 2K79B 1O4MA 1GRIA 1SHBA 1AYAA 3S8OA 2CI8A 3K2TA 2C9WA 2PLEA 1OPKA 5EELA 1R1PA 1UUSA 1JYQA 3VS7A 2EKXA 2IUGA 3N8MA 5J3XA 5BO4A 1O4LA 4F5AA 5D0JA 2DLZA 2H8HA 2MQIA 4FL3A 1OO3A 4FL2A 1H9OA 1O45A 1M61A 1RPYA 1R1QA 3IMJA 1JU5A 3KFJA 3VRQA 1P13A 1G83A 1PICA 2PLDA 1Y57A 1O41A 5CDWA 1CWDL 5DC9A 3MXYA 2KGYA 3LYVA 5GJHA 1BKMA 1QCFA 2MRJA 2YU7A 2RSYA 2MC1A 1OO4A 2C0OA 1O46A 3K2MA 3VS6A 1BHFA 3S8NA 1JYRA 1O4CA 3OB1B 1BLJA 3S8LA 1XA6A 2EL8A 1QADA 4K2RA 2AUGA 1SHAA 1X27A 1LUKA 1O4EA 1NZVA 1LCJA 1AOUF 4QSYA 4OHEA 3OP0A 1WQUA 1O4QA 2Y3AB 4K45A 3IN8A 2HMHA 3GXWA 2HCKA 1F2FA 5DF6A 5EHPA 2SHPA 1O4OA 3GQIB 1BHHB 3QWXX 2C0TA 3NHNA 4XZ1A 1O47A 5AXIA 2PNAA 3UF4A 1HCTB 3TKZA 2EOBA 1NRVA 1JYUA 2LQNA 1A1AA 5HKYA 1Z3KA 3OVEA 2AOAA 3BUXB 1BM2A 4A4CA 1IS0A 3OV1A 1FMKA 2ECDA 2VIFA 3BUWB 2Y1MA 4F5BA 1A08A 1YVHA 2EYYA 2RORA 2CIAA 1AOTF 2CR4A 2KNOA 2CI9A 3CD3A 1O4JA 1R1SA 1O4AA 2LQWA 1O4NA 1BLKA 5EHRA 2GSBA 3PSJA 3HIZB 1D1ZA 3PS5A 1F1WA 3N84A 4E68A 5HKZA 1AB2A 2IZVA 4JGHA 4TZIA 1SPSA 1BF5A 1X6CA 2EU0A 2HDVA 2RMXA 1SPRA 1LKLA 1A09A 1M27A 3PQZA 1O4KA 1B47A 2ETZA 1SHDA 1AYDA 2H46E 4A4BA 2DVJA 2XP1A 4K11A 1IJRA 1UURA 2FCIA 3HCKA 4P9ZA 1A1CA 1CSYA 5I6VA 2RVFA 3PSKA 3IN7A 3VRZA 3PFVA 1A07A 4NWGA 1LUNA 4EIHA 4D8KA 1KA7A 2L3TA 1TCEA 3VS1A 3UYOA 3BUMB 2DLYA 3ZNIA 4M4ZA 2B3OA 1CJ1A 1O4DA 3IMDA 1RQQC 3OB2B 1FBVA 3VRYA 4GWFA 2OZOA 1O4IA 1LCKA 1GHUA 2JYQA 1CWEA 2C0IA 1O4FA 2AOBA 3N7YA 2FO0A 3VS5A 2CS0A 1MILA 3S9KA 2GE9A 2EO3A 1JWOA 1O4GA 2DX0A 3BKBA 1A1EA 1O4RA 1ZFPE 3CXLA 3VS3A 3M7FA 2LNWA 1X0NA 4FBNA 4OHIA 1O49A 2MRKA 2KK6A 4EY0A 1O44A 3VGOA 2OQ1A 1FU5A 4OHLA 4LUDA 1O4PA 2CRHA 3VRRA 1O4HA 3TL0A 1Y1UA 1KSWA 4K44A 4L1BB 5DC4A 2K7AB 1O4BA 1A81A 4U1PA 3BUOB 3BUNB 4H34A 2EYZA 3QWYA 1AD5A 2LRAA 1BG1A 3GXXA 3VRNA 2LCTA 1D4WA 1D4TA 5HKWA 2IUHA 1MW4A 4XZ0A 2MK2A 1BHHA 4DGXA 3CBLA 3PJPA 2DCRA 2Y1NA
chains in the Genus database with same CATH topology
5KAZA 3WA4A 2CBLA 4E93A 4LUEA 1YVLA 3MAZA 1O43A 3VS2A 3VS4A 4F59A 5EEQA 5IBMA 3PLFB 1A1BA 1FHSA 2DM0A 1LKKA 3C7IA 2LNXA 1I3ZA 4P9VA 1TZEE 2PNBA 1FBZA 3MXCA 2YSXA 5DC0B 5IBSA 1KC2A 1FYRA 3T04A 2BBUA 4X6SA 2QMSA 4JE4A 3VROA 1O42A 1CSZA 1LUIA 2PTKA 3EACA 1KA6A 2H5KA 1AYCA 3US4A 4GPLB 3HHMB 2HDXA 4OHDA 3EAZA 5GJIA 2EYVA 4H1OA 2HUWA 1HCSB 4WWQA 2EO6A 1BFIA 1BMBA 4U17A 2ABLA 1OPLA 5AULA 1NZLA 4GL9E 2IUIA 1K9AA 2L4KA 1BFJA 3VRPA 4DGPA 4NWFA 4ROJA 3VS0A 1BKLA 4JEGA 1QG1E 5EG3B 4OHHA 3CWGA 1AYBA 1SKJA 2SRCA 2L6KA 1O48A 1FU6A 1RJAA 1LUMA 2K79B 1O4MA 1GRIA 1SHBA 1AYAA 3S8OA 2CI8A 2C9WA 2PLEA 1OPKA 5EELA 1R1PA 1UUSA 1JYQA 3VS7A 2EKXA 2IUGA 3N8MA 5J3XA 5BO4A 1O4LA 4F5AA 5D0JA 2DLZA 2H8HA 2MQIA 4FL3A 1OO3A 4FL2A 1H9OA 1O45A 1M61A 1RPYA 1R1QA 3IMJA 1JU5A 3KFJA 3VRQA 1P13A 1G83A 1PICA 2PLDA 1Y57A 1O41A 5CDWA 1CWDL 5DC9A 3MXYA 5GJHA 1BKMA 1QCFA 2MRJA 2YU7A 2RSYA 2MC1A 1OO4A 2C0OA 1O46A 3K2MA 3VS6A 1BHFA 3S8NA 1JYRA 1O4CA 3OB1B 1BLJA 3S8LA 1XA6A 2EL8A 1QADA 4K2RA 2AUGA 1SHAA 1X27A 1LUKA 1O4EA 1NZVA 1LCJA 1AOUF 4QSYA 4OHEA 3OP0A 1WQUA 1O4QA 2Y3AB 4K45A 3IN8A 2HMHA 3GXWA 2HCKA 1F2FA 5DF6A 5EHPA 2SHPA 1O4OA 3GQIB 1BHHB 3QWXX 2C0TA 3NHNA 4XZ1A 1O47A 5AXIA 2PNAA 3UF4A 1HCTB 3TKZA 2EOBA 1NRVA 1JYUA 2LQNA 1A1AA 5HKYA 1Z3KA 3OVEA 2AOAA 3BUXB 1BM2A 4A4CA 1IS0A 3OV1A 1FMKA 2ECDA 2VIFA 3BUWB 2Y1MA 4F5BA 1A08A 1YVHA 2EYYA 2RORA 2CIAA 1AOTF 2CR4A 2KNOA 2CI9A 3CD3A 1O4JA 1R1SA 1O4AA 2LQWA 1O4NA 1BLKA 5EHRA 2GSBA 3PSJA 3HIZB 1D1ZA 3PS5A 1F1WA 3N84A 4E68A 5HKZA 1AB2A 2IZVA 4JGHA 4TZIA 1SPSA 1BF5A 1X6CA 2EU0A 2HDVA 2RMXA 1SPRA 1LKLA 1A09A 1M27A 3PQZA 1O4KA 1B47A 2ETZA 1SHDA 1AYDA 2H46E 4A4BA 2DVJA 2XP1A 4K11A 1IJRA 1UURA 2FCIA 3HCKA 4P9ZA 1A1CA 1CSYA 5I6VA 2RVFA 3PSKA 3IN7A 3VRZA 3PFVA 1A07A 4NWGA 1LUNA 4EIHA 4D8KA 1KA7A 2L3TA 1TCEA 3VS1A 3UYOA 3BUMB 2DLYA 3ZNIA 4M4ZA 2B3OA 1CJ1A 1O4DA 3IMDA 1RQQC 3OB2B 1FBVA 3VRYA 4GWFA 2OZOA 1O4IA 1LCKA 1GHUA 2JYQA 1CWEA 2C0IA 1O4FA 2AOBA 3N7YA 2FO0A 3VS5A 2CS0A 1MILA 3S9KA 2GE9A 2EO3A 1JWOA 1O4GA 2DX0A 3BKBA 1A1EA 1O4RA 1ZFPE 3CXLA 3VS3A 3M7FA 2LNWA 1X0NA 4FBNA 4OHIA 1O49A 2MRKA 2KK6A 4EY0A 1O44A 3VGOA 2OQ1A 1FU5A 4OHLA 4LUDA 1O4PA 2CRHA 3VRRA 1O4HA 3TL0A 1Y1UA 1KSWA 4K44A 4L1BB 5DC4A 2K7AB 1O4BA 1A81A 4U1PA 3BUOB 3BUNB 4H34A 2EYZA 3QWYA 1AD5A 1BG1A 3GXXA 3VRNA 2LCTA 1D4WA 1D4TA 5HKWA 2IUHA 1MW4A 4XZ0A 2MK2A 1BHHA 4DGXA 3CBLA 3PJPA 2DCRA 2Y1NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KAZ A;  3WA4 A;  2CBL A;  4E93 A;  4LUE A;  1YVL A;  3MAZ A;  1O43 A;  3VS2 A;  3VS4 A;  4F59 A;  5EEQ A;  5IBM A;  3PLF B;  1A1B A;  1FHS A;  2DM0 A;  1LKK A;  3C7I A;  2LNX A;  1I3Z A;  4P9V A;  1TZE E;  2PNB A;  1FBZ A;  3MXC A;  2YSX A;  5DC0 B;  5IBS A;  1KC2 A;  1FYR A;  3T04 A;  2BBU A;  4X6S A;  2QMS A;  4JE4 A;  3VRO A;  1O42 A;  1CSZ A;  1LUI A;  2PTK A;  3EAC A;  1KA6 A;  2H5K A;  1AYC A;  3US4 A;  4GPL B;  3HHM B;  2HDX A;  4OHD A;  3EAZ A;  5GJI A;  2EYV A;  4H1O A;  2HUW A;  1HCS B;  4WWQ A;  2EO6 A;  1BFI A;  1BMB A;  4U17 A;  2ABL A;  1OPL A;  5AUL A;  1NZL A;  4GL9 E;  2IUI A;  1K9A A;  2L4K A;  1BFJ A;  3VRP A;  4DGP A;  4NWF A;  4ROJ A;  3VS0 A;  1BKL A;  4JEG A;  1QG1 E;  5EG3 B;  4OHH A;  3CWG A;  1AYB A;  1SKJ A;  2SRC A;  2L6K A;  1O48 A;  1FU6 A;  1RJA A;  1LUM A;  2K79 B;  1O4M A;  1GRI A;  1SHB A;  1AYA A;  3S8O A;  2CI8 A;  2C9W A;  2PLE A;  1OPK A;  5EEL A;  1R1P A;  1UUS A;  1JYQ A;  3VS7 A;  2EKX A;  2IUG A;  3N8M A;  5J3X A;  5BO4 A;  1O4L A;  4F5A A;  5D0J A;  2DLZ A;  2H8H A;  2MQI A;  4FL3 A;  1OO3 A;  4FL2 A;  1H9O A;  1O45 A;  1M61 A;  1RPY A;  1R1Q A;  3IMJ A;  1JU5 A;  3KFJ A;  3VRQ A;  1P13 A;  1G83 A;  1PIC A;  2PLD A;  1Y57 A;  1O41 A;  5CDW A;  1CWD L;  5DC9 A;  3MXY A;  5GJH A;  1BKM A;  1QCF A;  2MRJ A;  2YU7 A;  2RSY A;  2MC1 A;  1OO4 A;  2C0O A;  1O46 A;  3K2M A;  3VS6 A;  1BHF A;  3S8N A;  1JYR A;  1O4C A;  3OB1 B;  1BLJ A;  3S8L A;  1XA6 A;  2EL8 A;  1QAD A;  4K2R A;  2AUG A;  1SHA A;  1X27 A;  1LUK A;  1O4E A;  1NZV A;  1LCJ A;  1AOU F;  4QSY A;  4OHE A;  3OP0 A;  1WQU A;  1O4Q A;  2Y3A B;  4K45 A;  3IN8 A;  2HMH A;  3GXW A;  2HCK A;  1F2F A;  5DF6 A;  5EHP A;  2SHP A;  1O4O A;  3GQI B;  1BHH B;  3QWX X;  2C0T A;  3NHN A;  4XZ1 A;  1O47 A;  5AXI A;  2PNA A;  3UF4 A;  1HCT B;  3TKZ A;  2EOB A;  1NRV A;  1JYU A;  2LQN A;  1A1A A;  5HKY A;  1Z3K A;  3OVE A;  2AOA A;  3BUX B;  1BM2 A;  4A4C A;  1IS0 A;  3OV1 A;  1FMK A;  2ECD A;  2VIF A;  3BUW B;  2Y1M A;  4F5B A;  1A08 A;  1YVH A;  2EYY A;  2ROR A;  2CIA A;  1AOT F;  2CR4 A;  2KNO A;  2CI9 A;  3CD3 A;  1O4J A;  1R1S A;  1O4A A;  2LQW A;  1O4N A;  1BLK A;  5EHR A;  2GSB A;  3PSJ A;  3HIZ B;  1D1Z A;  3PS5 A;  1F1W A;  3N84 A;  4E68 A;  5HKZ A;  1AB2 A;  2IZV A;  4JGH A;  4TZI A;  1SPS A;  1BF5 A;  1X6C A;  2EU0 A;  2HDV A;  2RMX A;  1SPR A;  1LKL A;  1A09 A;  1M27 A;  3PQZ A;  1O4K A;  1B47 A;  2ETZ A;  1SHD A;  1AYD A;  2H46 E;  4A4B A;  2DVJ A;  2XP1 A;  4K11 A;  1IJR A;  1UUR A;  2FCI A;  3HCK A;  4P9Z A;  1A1C A;  1CSY A;  5I6V A;  2RVF A;  3PSK A;  3IN7 A;  3VRZ A;  3PFV A;  1A07 A;  4NWG A;  1LUN A;  4EIH A;  4D8K A;  1KA7 A;  2L3T A;  1TCE A;  3VS1 A;  3UYO A;  3BUM B;  2DLY A;  3ZNI A;  4M4Z A;  2B3O A;  1CJ1 A;  1O4D A;  3IMD A;  1RQQ C;  3OB2 B;  1FBV A;  3VRY A;  4GWF A;  2OZO A;  1O4I A;  1LCK A;  1GHU A;  2JYQ A;  1CWE A;  2C0I A;  1O4F A;  2AOB A;  3N7Y A;  2FO0 A;  3VS5 A;  2CS0 A;  1MIL A;  3S9K A;  2GE9 A;  2EO3 A;  1JWO A;  1O4G A;  2DX0 A;  3BKB A;  1A1E A;  1O4R A;  1ZFP E;  3CXL A;  3VS3 A;  3M7F A;  2LNW A;  1X0N A;  4FBN A;  4OHI A;  1O49 A;  2MRK A;  2KK6 A;  4EY0 A;  1O44 A;  3VGO A;  2OQ1 A;  1FU5 A;  4OHL A;  4LUD A;  1O4P A;  2CRH A;  3VRR A;  1O4H A;  3TL0 A;  1Y1U A;  1KSW A;  4K44 A;  4L1B B;  5DC4 A;  2K7A B;  1O4B A;  1A81 A;  4U1P A;  3BUO B;  3BUN B;  4H34 A;  2EYZ A;  3QWY A;  1AD5 A;  1BG1 A;  3GXX A;  3VRN A;  2LCT A;  1D4W A;  1D4T A;  5HKW A;  2IUH A;  1MW4 A;  4XZ0 A;  2MK2 A;  1BHH A;  4DGX A;  3CBL A;  3PJP A;  2DCR A;  2Y1N A; 
#chains in the Genus database with same CATH topology
 5KAZ A;  3WA4 A;  2CBL A;  4E93 A;  4LUE A;  1YVL A;  3MAZ A;  1O43 A;  3VS2 A;  3VS4 A;  4F59 A;  5EEQ A;  5IBM A;  3PLF B;  1A1B A;  1FHS A;  2DM0 A;  1LKK A;  3C7I A;  2LNX A;  1I3Z A;  4P9V A;  1TZE E;  2PNB A;  1FBZ A;  3MXC A;  2YSX A;  5DC0 B;  5IBS A;  1KC2 A;  1FYR A;  3T04 A;  2BBU A;  4X6S A;  2QMS A;  4JE4 A;  3VRO A;  1O42 A;  1CSZ A;  1LUI A;  2PTK A;  3EAC A;  1KA6 A;  2H5K A;  1AYC A;  3US4 A;  4GPL B;  3HHM B;  2HDX A;  4OHD A;  3EAZ A;  5GJI A;  2EYV A;  4H1O A;  2HUW A;  1HCS B;  4WWQ A;  2EO6 A;  1BFI A;  1BMB A;  4U17 A;  2ABL A;  1OPL A;  5AUL A;  1NZL A;  4GL9 E;  2IUI A;  1K9A A;  2L4K A;  1BFJ A;  3VRP A;  4DGP A;  4NWF A;  4ROJ A;  3VS0 A;  1BKL A;  4JEG A;  1QG1 E;  5EG3 B;  4OHH A;  3CWG A;  1AYB A;  1SKJ A;  2SRC A;  2L6K A;  1O48 A;  1FU6 A;  1RJA A;  1LUM A;  2K79 B;  1O4M A;  1GRI A;  1SHB A;  1AYA A;  3S8O A;  2CI8 A;  3K2T A;  2C9W A;  2PLE A;  1OPK A;  5EEL A;  1R1P A;  1UUS A;  1JYQ A;  3VS7 A;  2EKX A;  2IUG A;  3N8M A;  5J3X A;  5BO4 A;  1O4L A;  4F5A A;  5D0J A;  2DLZ A;  2H8H A;  2MQI A;  4FL3 A;  1OO3 A;  4FL2 A;  1H9O A;  1O45 A;  1M61 A;  1RPY A;  1R1Q A;  3IMJ A;  1JU5 A;  3KFJ A;  3VRQ A;  1P13 A;  1G83 A;  1PIC A;  2PLD A;  1Y57 A;  1O41 A;  5CDW A;  1CWD L;  5DC9 A;  3MXY A;  2KGY A;  3LYV A;  5GJH A;  1BKM A;  1QCF A;  2MRJ A;  2YU7 A;  2RSY A;  2MC1 A;  1OO4 A;  2C0O A;  1O46 A;  3K2M A;  3VS6 A;  1BHF A;  3S8N A;  1JYR A;  1O4C A;  3OB1 B;  1BLJ A;  3S8L A;  1XA6 A;  2EL8 A;  1QAD A;  4K2R A;  2AUG A;  1SHA A;  1X27 A;  1LUK A;  1O4E A;  1NZV A;  1LCJ A;  1AOU F;  4QSY A;  4OHE A;  3OP0 A;  1WQU A;  1O4Q A;  2Y3A B;  4K45 A;  3IN8 A;  2HMH A;  3GXW A;  2HCK A;  1F2F A;  5DF6 A;  5EHP A;  2SHP A;  1O4O A;  3GQI B;  1BHH B;  3QWX X;  2C0T A;  3NHN A;  4XZ1 A;  1O47 A;  5AXI A;  2PNA A;  3UF4 A;  1HCT B;  3TKZ A;  2EOB A;  1NRV A;  1JYU A;  2LQN A;  1A1A A;  5HKY A;  1Z3K A;  3OVE A;  2AOA A;  3BUX B;  1BM2 A;  4A4C A;  1IS0 A;  3OV1 A;  1FMK A;  2ECD A;  2VIF A;  3BUW B;  2Y1M A;  4F5B A;  1A08 A;  1YVH A;  2EYY A;  2ROR A;  2CIA A;  1AOT F;  2CR4 A;  2KNO A;  2CI9 A;  3CD3 A;  1O4J A;  1R1S A;  1O4A A;  2LQW A;  1O4N A;  1BLK A;  5EHR A;  2GSB A;  3PSJ A;  3HIZ B;  1D1Z A;  3PS5 A;  1F1W A;  3N84 A;  4E68 A;  5HKZ A;  1AB2 A;  2IZV A;  4JGH A;  4TZI A;  1SPS A;  1BF5 A;  1X6C A;  2EU0 A;  2HDV A;  2RMX A;  1SPR A;  1LKL A;  1A09 A;  1M27 A;  3PQZ A;  1O4K A;  1B47 A;  2ETZ A;  1SHD A;  1AYD A;  2H46 E;  4A4B A;  2DVJ A;  2XP1 A;  4K11 A;  1IJR A;  1UUR A;  2FCI A;  3HCK A;  4P9Z A;  1A1C A;  1CSY A;  5I6V A;  2RVF A;  3PSK A;  3IN7 A;  3VRZ A;  3PFV A;  1A07 A;  4NWG A;  1LUN A;  4EIH A;  4D8K A;  1KA7 A;  2L3T A;  1TCE A;  3VS1 A;  3UYO A;  3BUM B;  2DLY A;  3ZNI A;  4M4Z A;  2B3O A;  1CJ1 A;  1O4D A;  3IMD A;  1RQQ C;  3OB2 B;  1FBV A;  3VRY A;  4GWF A;  2OZO A;  1O4I A;  1LCK A;  1GHU A;  2JYQ A;  1CWE A;  2C0I A;  1O4F A;  2AOB A;  3N7Y A;  2FO0 A;  3VS5 A;  2CS0 A;  1MIL A;  3S9K A;  2GE9 A;  2EO3 A;  1JWO A;  1O4G A;  2DX0 A;  3BKB A;  1A1E A;  1O4R A;  1ZFP E;  3CXL A;  3VS3 A;  3M7F A;  2LNW A;  1X0N A;  4FBN A;  4OHI A;  1O49 A;  2MRK A;  2KK6 A;  4EY0 A;  1O44 A;  3VGO A;  2OQ1 A;  1FU5 A;  4OHL A;  4LUD A;  1O4P A;  2CRH A;  3VRR A;  1O4H A;  3TL0 A;  1Y1U A;  1KSW A;  4K44 A;  4L1B B;  5DC4 A;  2K7A B;  1O4B A;  1A81 A;  4U1P A;  3BUO B;  3BUN B;  4H34 A;  2EYZ A;  3QWY A;  1AD5 A;  2LRA A;  1BG1 A;  3GXX A;  3VRN A;  2LCT A;  1D4W A;  1D4T A;  5HKW A;  2IUH A;  1MW4 A;  4XZ0 A;  2MK2 A;  1BHH A;  4DGX A;  3CBL A;  3PJP A;  2DCR A;  2Y1N A; 
#chains in the Genus database with same CATH homology
 5KAZ A;  3WA4 A;  2CBL A;  4E93 A;  4LUE A;  1YVL A;  3MAZ A;  1O43 A;  3VS2 A;  3VS4 A;  4F59 A;  5EEQ A;  5IBM A;  3PLF B;  1A1B A;  1FHS A;  2DM0 A;  1LKK A;  3C7I A;  2LNX A;  1I3Z A;  4P9V A;  1TZE E;  2PNB A;  1FBZ A;  3MXC A;  2YSX A;  5DC0 B;  5IBS A;  1KC2 A;  1FYR A;  3T04 A;  2BBU A;  4X6S A;  2QMS A;  4JE4 A;  3VRO A;  1O42 A;  1CSZ A;  1LUI A;  2PTK A;  3EAC A;  1KA6 A;  2H5K A;  1AYC A;  3US4 A;  4GPL B;  3HHM B;  2HDX A;  4OHD A;  3EAZ A;  5GJI A;  2EYV A;  4H1O A;  2HUW A;  1HCS B;  4WWQ A;  2EO6 A;  1BFI A;  1BMB A;  4U17 A;  2ABL A;  1OPL A;  5AUL A;  1NZL A;  4GL9 E;  2IUI A;  1K9A A;  2L4K A;  1BFJ A;  3VRP A;  4DGP A;  4NWF A;  4ROJ A;  3VS0 A;  1BKL A;  4JEG A;  1QG1 E;  5EG3 B;  4OHH A;  3CWG A;  1AYB A;  1SKJ A;  2SRC A;  2L6K A;  1O48 A;  1FU6 A;  1RJA A;  1LUM A;  2K79 B;  1O4M A;  1GRI A;  1SHB A;  1AYA A;  3S8O A;  2CI8 A;  2C9W A;  2PLE A;  1OPK A;  5EEL A;  1R1P A;  1UUS A;  1JYQ A;  3VS7 A;  2EKX A;  2IUG A;  3N8M A;  5J3X A;  5BO4 A;  1O4L A;  4F5A A;  5D0J A;  2DLZ A;  2H8H A;  2MQI A;  4FL3 A;  1OO3 A;  4FL2 A;  1H9O A;  1O45 A;  1M61 A;  1RPY A;  1R1Q A;  3IMJ A;  1JU5 A;  3KFJ A;  3VRQ A;  1P13 A;  1G83 A;  1PIC A;  2PLD A;  1Y57 A;  1O41 A;  5CDW A;  1CWD L;  5DC9 A;  3MXY A;  5GJH A;  1BKM A;  1QCF A;  2MRJ A;  2YU7 A;  2RSY A;  2MC1 A;  1OO4 A;  2C0O A;  1O46 A;  3K2M A;  3VS6 A;  1BHF A;  3S8N A;  1JYR A;  1O4C A;  3OB1 B;  1BLJ A;  3S8L A;  1XA6 A;  2EL8 A;  1QAD A;  4K2R A;  2AUG A;  1SHA A;  1X27 A;  1LUK A;  1O4E A;  1NZV A;  1LCJ A;  1AOU F;  4QSY A;  4OHE A;  3OP0 A;  1WQU A;  1O4Q A;  2Y3A B;  4K45 A;  3IN8 A;  2HMH A;  3GXW A;  2HCK A;  1F2F A;  5DF6 A;  5EHP A;  2SHP A;  1O4O A;  3GQI B;  1BHH B;  3QWX X;  2C0T A;  3NHN A;  4XZ1 A;  1O47 A;  5AXI A;  2PNA A;  3UF4 A;  1HCT B;  3TKZ A;  2EOB A;  1NRV A;  1JYU A;  2LQN A;  1A1A A;  5HKY A;  1Z3K A;  3OVE A;  2AOA A;  3BUX B;  1BM2 A;  4A4C A;  1IS0 A;  3OV1 A;  1FMK A;  2ECD A;  2VIF A;  3BUW B;  2Y1M A;  4F5B A;  1A08 A;  1YVH A;  2EYY A;  2ROR A;  2CIA A;  1AOT F;  2CR4 A;  2KNO A;  2CI9 A;  3CD3 A;  1O4J A;  1R1S A;  1O4A A;  2LQW A;  1O4N A;  1BLK A;  5EHR A;  2GSB A;  3PSJ A;  3HIZ B;  1D1Z A;  3PS5 A;  1F1W A;  3N84 A;  4E68 A;  5HKZ A;  1AB2 A;  2IZV A;  4JGH A;  4TZI A;  1SPS A;  1BF5 A;  1X6C A;  2EU0 A;  2HDV A;  2RMX A;  1SPR A;  1LKL A;  1A09 A;  1M27 A;  3PQZ A;  1O4K A;  1B47 A;  2ETZ A;  1SHD A;  1AYD A;  2H46 E;  4A4B A;  2DVJ A;  2XP1 A;  4K11 A;  1IJR A;  1UUR A;  2FCI A;  3HCK A;  4P9Z A;  1A1C A;  1CSY A;  5I6V A;  2RVF A;  3PSK A;  3IN7 A;  3VRZ A;  3PFV A;  1A07 A;  4NWG A;  1LUN A;  4EIH A;  4D8K A;  1KA7 A;  2L3T A;  1TCE A;  3VS1 A;  3UYO A;  3BUM B;  2DLY A;  3ZNI A;  4M4Z A;  2B3O A;  1CJ1 A;  1O4D A;  3IMD A;  1RQQ C;  3OB2 B;  1FBV A;  3VRY A;  4GWF A;  2OZO A;  1O4I A;  1LCK A;  1GHU A;  2JYQ A;  1CWE A;  2C0I A;  1O4F A;  2AOB A;  3N7Y A;  2FO0 A;  3VS5 A;  2CS0 A;  1MIL A;  3S9K A;  2GE9 A;  2EO3 A;  1JWO A;  1O4G A;  2DX0 A;  3BKB A;  1A1E A;  1O4R A;  1ZFP E;  3CXL A;  3VS3 A;  3M7F A;  2LNW A;  1X0N A;  4FBN A;  4OHI A;  1O49 A;  2MRK A;  2KK6 A;  4EY0 A;  1O44 A;  3VGO A;  2OQ1 A;  1FU5 A;  4OHL A;  4LUD A;  1O4P A;  2CRH A;  3VRR A;  1O4H A;  3TL0 A;  1Y1U A;  1KSW A;  4K44 A;  4L1B B;  5DC4 A;  2K7A B;  1O4B A;  1A81 A;  4U1P A;  3BUO B;  3BUN B;  4H34 A;  2EYZ A;  3QWY A;  1AD5 A;  1BG1 A;  3GXX A;  3VRN A;  2LCT A;  1D4W A;  1D4T A;  5HKW A;  2IUH A;  1MW4 A;  4XZ0 A;  2MK2 A;  1BHH A;  4DGX A;  3CBL A;  3PJP A;  2DCR A;  2Y1N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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