1GHUA

Nmr solution structure of growth factor receptor-bound protein 2 (grb2) sh2 domain, 24 structures
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
95
structure length
95
Chain Sequence
GSWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain.
pubmed doi rcsb
molecule tags Src homology 2 domain
source organism Homo sapiens
molecule keywords GRB2
total genus 17
structure length 95
sequence length 95
ec nomenclature
pdb deposition date 1996-08-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1ghuA00
1A1AA 3EACA 3VS6A 3WA4A 1FU5A 1JU5A 2GSBA 1M61A 2C9WA 1OPLA 4L1BB 1X6CA 4JE4A 1KSWA 1X0NA 2PTKA 4QSYA 3PS5A 1FBVA 3VRRA 2FCIA 3IN7A 3VGOA 4LUDA 2MQIA 5IBSA 1O4FA 5EG3B 1LUKA 2L4KA 2PNAA 1BHHB 3PJPA 1CWEA 5EELA 1ZFPE 1FBZA 3PQZA 3VROA 1BKMA 2RSYA 3HHMB 5I6VA 1Y57A 1LUNA 2CI9A 1CSZA 3CXLA 4P9VA 1O43A 3HCKA 1BM2A 3S9KA 1A1CA 4EIHA 5CDWA 1O4NA 3PSKA 3UYOA 1QCFA 2FO0A 1P13A 1I3ZA 1WQUA 1O45A 1XA6A 2ECDA 2IUHA 3OV1A 1A09A 2MRJA 3MAZA 1LKLA 2KNOA 4H34A 2AUGA 3N8MA 1JYRA 1O4QA 1JWOA 3MXCA 5DC4A 5DF6A 2CRHA 2DCRA 2LNWA 1KA7A 3OP0A 1UURA 2PLDA 1O48A 1O47A 1CSYA 1BF5A 5HKYA 1Z3KA 3VRPA 1A1EA 2JYQA 2QMSA 4X6SA 2CI8A 5J3XA 1OO4A 4A4BA 2DLYA 3M7FA 1QADA 2EOBA 1AOUF 1O4OA 2IZVA 1A1BA 2IUIA 3T04A 3IMJA 2C0IA 4F5AA 3C7IA 1AYCA 3S8LA 1A07A 2HUWA 2K7AB 2CIAA 1M27A 3CWGA 2C0TA 2ABLA 3OB2B 1MILA 4LUEA 4TZIA 3N7YA 4U17A 1FYRA 3VS0A 3EAZA 5AXIA 3VS4A 2CR4A 1YVLA 3VRZA 1R1QA 1TCEA 1O4PA 5BO4A 3GXWA 1BMBA 4E93A 1LUIA 2XP1A 4K11A 2EO6A 2LCTA 1FHSA 1O4GA 5HKWA 1A08A 1FU6A 1O46A 1MW4A 3N84A 3IN8A 1AD5A 1O4RA 3PSJA 4A4CA 1K9AA 4U1PA 2MK2A 1LUMA 1NZLA 1IS0A 2L6KA 3NHNA 1AYDA 5EHPA 4XZ0A 4NWFA 2CBLA 3MXYA 2AOAA 1R1SA 1O4MA 1KC2A 2RMXA 1BFJA 3BUWB 3PLFB 4D8KA 1O42A 3BUNB 1JYUA 3TL0A 1HCTB 2HDXA 1O4KA 1D1ZA 1O4JA 4OHHA 3OVEA 2H46E 3BKBA 1BLKA 1LCJA 4M4ZA 2CS0A 3BUOB 1RJAA 3CBLA 3VS1A 3QWYA 1IJRA 4K44A 3IMDA 3UF4A 3CD3A 2H8HA 1O4EA 1YVHA 1RPYA 2HCKA 4JGHA 1BFIA 1AYBA 1O4AA 1O4IA 4DGXA 1JYQA 1D4WA 4FBNA 2HDVA 2L3TA 1TZEE 1O44A 3KFJA 5D0JA 2EKXA 1LCKA 4F5BA 3S8NA 1AB2A 1KA6A 1FMKA 5KAZA 4FL2A 1B47A 1SHDA 1CJ1A 5HKZA 3VS3A 4FL3A 1RQQC 2EO3A 1O41A 2Y1MA 3GXXA 5EHRA 4E68A 4K2RA 3US4A 2SRCA 5DC9A 2AOBA 5IBMA 1CWDL 4DGPA 1A81A 3VRYA 4EY0A 1G83A 2YSXA 2RVFA 1O4HA 1SPRA 3OB1B 5EEQA 3VRQA 2BBUA 1SKJA 1BKLA 1O4LA 1NZVA 2MRKA 1AYAA 2Y1NA 4OHIA 1O4BA 3K2MA 1SHAA 4JEGA 4ROJA 2RORA 4F59A 1QG1E 2OZOA 1D4TA 2EYZA 3VRNA 2GE9A 5GJIA 4P9ZA 2Y3AB 4K45A 1F2FA 3VS7A 1BG1A 2DM0A 3HIZB 5DC0B 1BLJA 2C0OA 4GWFA 2DX0A 1PICA 1Y1UA 1BHHA 3BUMB 3BUXB 2VIFA 2LQNA 2LQWA 2ETZA 1SHBA 2EL8A 2K79B 1R1PA 4H1OA 1X27A 1SPSA 1O49A 1GHUA 3GQIB 2EYVA 3TKZA 3ZNIA 1UUSA 2YU7A 1LKKA 2MC1A 2IUGA 1AOTF 4OHDA 5GJHA 1NRVA 2DLZA 2KK6A 2EU0A 1O4CA 2EYYA 2PNBA 4OHEA 4WWQA 2B3OA 2DVJA 3QWXX 4OHLA 2SHPA 2LNXA 4XZ1A 3VS2A 2H5KA 2OQ1A 2PLEA 3VS5A 5AULA 2HMHA 1BHFA 1OPKA 3S8OA 1GRIA 1O4DA 1HCSB 3PFVA 4GPLB 1H9OA 1OO3A 4NWGA 4GL9E 1F1WA
chains in the Genus database with same CATH superfamily
1A1AA 3EACA 3VS6A 3WA4A 1FU5A 1JU5A 2GSBA 1M61A 2C9WA 1OPLA 4L1BB 1X6CA 4JE4A 1KSWA 1X0NA 2PTKA 4QSYA 3PS5A 1FBVA 3VRRA 2FCIA 3IN7A 3VGOA 4LUDA 2MQIA 5IBSA 1O4FA 5EG3B 1LUKA 2L4KA 2PNAA 1BHHB 3PJPA 1CWEA 5EELA 1ZFPE 1FBZA 3PQZA 3VROA 1BKMA 2RSYA 2LRAA 3HHMB 5I6VA 1Y57A 1LUNA 2CI9A 1CSZA 3CXLA 4P9VA 1O43A 3HCKA 1BM2A 3S9KA 1A1CA 4EIHA 5CDWA 1O4NA 3PSKA 3UYOA 1QCFA 2FO0A 1P13A 1I3ZA 1WQUA 1O45A 1XA6A 2ECDA 2IUHA 3OV1A 1A09A 2MRJA 3MAZA 1LKLA 2KNOA 4H34A 2AUGA 3N8MA 1JYRA 1O4QA 1JWOA 3MXCA 5DC4A 5DF6A 2CRHA 2DCRA 2LNWA 1KA7A 3OP0A 1UURA 2PLDA 1O48A 1O47A 1CSYA 1BF5A 5HKYA 1Z3KA 3VRPA 1A1EA 2JYQA 2QMSA 4X6SA 2CI8A 5J3XA 1OO4A 4A4BA 2DLYA 3M7FA 1QADA 2EOBA 1AOUF 1O4OA 2IZVA 1A1BA 2IUIA 3T04A 3IMJA 2C0IA 4F5AA 3C7IA 1AYCA 3S8LA 1A07A 2HUWA 2K7AB 2CIAA 1M27A 3CWGA 2C0TA 2ABLA 3OB2B 1MILA 4LUEA 4TZIA 3N7YA 4U17A 1FYRA 3VS0A 3EAZA 5AXIA 3VS4A 2CR4A 1YVLA 3VRZA 1R1QA 1TCEA 1O4PA 5BO4A 3GXWA 1BMBA 4E93A 1LUIA 2XP1A 4K11A 2EO6A 2LCTA 1FHSA 1O4GA 5HKWA 1A08A 1FU6A 1O46A 1MW4A 3N84A 3IN8A 1AD5A 1O4RA 3PSJA 4A4CA 1K9AA 4U1PA 2MK2A 1LUMA 1NZLA 1IS0A 2L6KA 3NHNA 1AYDA 5EHPA 4XZ0A 4NWFA 2CBLA 3MXYA 2AOAA 1R1SA 1O4MA 1KC2A 2RMXA 1BFJA 3BUWB 3PLFB 4D8KA 1O42A 3BUNB 1JYUA 3TL0A 1HCTB 2HDXA 1O4KA 1D1ZA 1O4JA 4OHHA 3OVEA 2H46E 3BKBA 1BLKA 1LCJA 4M4ZA 2CS0A 3BUOB 1RJAA 3CBLA 3VS1A 3QWYA 1IJRA 4K44A 3IMDA 3UF4A 3CD3A 2H8HA 1O4EA 1YVHA 1RPYA 2HCKA 4JGHA 1BFIA 1AYBA 1O4AA 1O4IA 4DGXA 1JYQA 1D4WA 4FBNA 2HDVA 2L3TA 1TZEE 1O44A 3KFJA 5D0JA 2EKXA 1LCKA 4F5BA 3S8NA 1AB2A 1KA6A 1FMKA 5KAZA 4FL2A 1B47A 1SHDA 1CJ1A 5HKZA 3VS3A 4FL3A 1RQQC 2EO3A 1O41A 2Y1MA 3GXXA 5EHRA 4E68A 4K2RA 3US4A 2SRCA 5DC9A 2AOBA 5IBMA 1CWDL 4DGPA 1A81A 3VRYA 4EY0A 1G83A 2YSXA 2RVFA 1O4HA 1SPRA 3OB1B 5EEQA 3VRQA 2BBUA 1SKJA 1BKLA 1O4LA 1NZVA 2MRKA 1AYAA 2KGYA 2Y1NA 4OHIA 1O4BA 3K2MA 1SHAA 4JEGA 4ROJA 2RORA 4F59A 1QG1E 2OZOA 3LYVA 1D4TA 2EYZA 3VRNA 2GE9A 5GJIA 4P9ZA 2Y3AB 4K45A 1F2FA 3VS7A 1BG1A 2DM0A 3HIZB 5DC0B 1BLJA 2C0OA 4GWFA 2DX0A 1PICA 1Y1UA 1BHHA 3BUMB 3BUXB 2VIFA 2LQNA 2LQWA 2ETZA 1SHBA 2EL8A 2K79B 1R1PA 4H1OA 1X27A 1SPSA 1O49A 1GHUA 3GQIB 2EYVA 3TKZA 3ZNIA 1UUSA 2YU7A 1LKKA 2MC1A 2IUGA 1AOTF 4OHDA 5GJHA 1NRVA 2DLZA 2KK6A 2EU0A 1O4CA 2EYYA 2PNBA 4OHEA 4WWQA 2B3OA 2DVJA 3QWXX 3K2TA 4OHLA 2SHPA 2LNXA 4XZ1A 3VS2A 2H5KA 2OQ1A 2PLEA 3VS5A 5AULA 2HMHA 1BHFA 1OPKA 3S8OA 1GRIA 1O4DA 1HCSB 3PFVA 4GPLB 1H9OA 1OO3A 4NWGA 4GL9E 1F1WA
chains in the Genus database with same CATH topology
1A1AA 3EACA 3VS6A 3WA4A 1FU5A 1JU5A 2GSBA 1M61A 2C9WA 1OPLA 4L1BB 1X6CA 4JE4A 1KSWA 1X0NA 2PTKA 4QSYA 3PS5A 1FBVA 3VRRA 2FCIA 3IN7A 3VGOA 4LUDA 2MQIA 5IBSA 1O4FA 5EG3B 1LUKA 2L4KA 2PNAA 1BHHB 3PJPA 1CWEA 5EELA 1ZFPE 1FBZA 3PQZA 3VROA 1BKMA 2RSYA 3HHMB 5I6VA 1Y57A 1LUNA 2CI9A 1CSZA 3CXLA 4P9VA 1O43A 3HCKA 1BM2A 3S9KA 1A1CA 4EIHA 5CDWA 1O4NA 3PSKA 3UYOA 1QCFA 2FO0A 1P13A 1I3ZA 1WQUA 1O45A 1XA6A 2ECDA 2IUHA 3OV1A 1A09A 2MRJA 3MAZA 1LKLA 2KNOA 4H34A 2AUGA 3N8MA 1JYRA 1O4QA 1JWOA 3MXCA 5DC4A 5DF6A 2CRHA 2DCRA 2LNWA 1KA7A 3OP0A 1UURA 2PLDA 1O48A 1O47A 1CSYA 1BF5A 5HKYA 1Z3KA 3VRPA 1A1EA 2JYQA 2QMSA 4X6SA 2CI8A 5J3XA 1OO4A 4A4BA 2DLYA 3M7FA 1QADA 2EOBA 1AOUF 1O4OA 2IZVA 1A1BA 2IUIA 3T04A 3IMJA 2C0IA 4F5AA 3C7IA 1AYCA 3S8LA 1A07A 2HUWA 2K7AB 2CIAA 1M27A 3CWGA 2C0TA 2ABLA 3OB2B 1MILA 4LUEA 4TZIA 3N7YA 4U17A 1FYRA 3VS0A 3EAZA 5AXIA 3VS4A 2CR4A 1YVLA 3VRZA 1R1QA 1TCEA 1O4PA 5BO4A 3GXWA 1BMBA 4E93A 1LUIA 2XP1A 4K11A 2EO6A 2LCTA 1FHSA 1O4GA 5HKWA 1A08A 1FU6A 1O46A 1MW4A 3N84A 3IN8A 1AD5A 1O4RA 3PSJA 4A4CA 1K9AA 4U1PA 2MK2A 1LUMA 1NZLA 1IS0A 2L6KA 3NHNA 1AYDA 5EHPA 4XZ0A 4NWFA 2CBLA 3MXYA 2AOAA 1R1SA 1O4MA 1KC2A 2RMXA 1BFJA 3BUWB 3PLFB 4D8KA 1O42A 3BUNB 1JYUA 3TL0A 1HCTB 2HDXA 1O4KA 1D1ZA 1O4JA 4OHHA 3OVEA 2H46E 3BKBA 1BLKA 1LCJA 4M4ZA 2CS0A 3BUOB 1RJAA 3CBLA 3VS1A 3QWYA 1IJRA 4K44A 3IMDA 3UF4A 3CD3A 2H8HA 1O4EA 1YVHA 1RPYA 2HCKA 4JGHA 1BFIA 1AYBA 1O4AA 1O4IA 4DGXA 1JYQA 1D4WA 4FBNA 2HDVA 2L3TA 1TZEE 1O44A 3KFJA 5D0JA 2EKXA 1LCKA 4F5BA 3S8NA 1AB2A 1KA6A 1FMKA 5KAZA 4FL2A 1B47A 1SHDA 1CJ1A 5HKZA 3VS3A 4FL3A 1RQQC 2EO3A 1O41A 2Y1MA 3GXXA 5EHRA 4E68A 4K2RA 3US4A 2SRCA 5DC9A 2AOBA 5IBMA 1CWDL 4DGPA 1A81A 3VRYA 4EY0A 1G83A 2YSXA 2RVFA 1O4HA 1SPRA 3OB1B 5EEQA 3VRQA 2BBUA 1SKJA 1BKLA 1O4LA 1NZVA 2MRKA 1AYAA 2Y1NA 4OHIA 1O4BA 3K2MA 1SHAA 4JEGA 4ROJA 2RORA 4F59A 1QG1E 2OZOA 1D4TA 2EYZA 3VRNA 2GE9A 5GJIA 4P9ZA 2Y3AB 4K45A 1F2FA 3VS7A 1BG1A 2DM0A 3HIZB 5DC0B 1BLJA 2C0OA 4GWFA 2DX0A 1PICA 1Y1UA 1BHHA 3BUMB 3BUXB 2VIFA 2LQNA 2LQWA 2ETZA 1SHBA 2EL8A 2K79B 1R1PA 4H1OA 1X27A 1SPSA 1O49A 1GHUA 3GQIB 2EYVA 3TKZA 3ZNIA 1UUSA 2YU7A 1LKKA 2MC1A 2IUGA 1AOTF 4OHDA 5GJHA 1NRVA 2DLZA 2KK6A 2EU0A 1O4CA 2EYYA 2PNBA 4OHEA 4WWQA 2B3OA 2DVJA 3QWXX 4OHLA 2SHPA 2LNXA 4XZ1A 3VS2A 2H5KA 2OQ1A 2PLEA 3VS5A 5AULA 2HMHA 1BHFA 1OPKA 3S8OA 1GRIA 1O4DA 1HCSB 3PFVA 4GPLB 1H9OA 1OO3A 4NWGA 4GL9E 1F1WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A1A A;  3EAC A;  3VS6 A;  3WA4 A;  1FU5 A;  1JU5 A;  2GSB A;  1M61 A;  2C9W A;  1OPL A;  4L1B B;  1X6C A;  4JE4 A;  1KSW A;  1X0N A;  2PTK A;  4QSY A;  3PS5 A;  1FBV A;  3VRR A;  2FCI A;  3IN7 A;  3VGO A;  4LUD A;  2MQI A;  5IBS A;  1O4F A;  5EG3 B;  1LUK A;  2L4K A;  2PNA A;  1BHH B;  3PJP A;  1CWE A;  5EEL A;  1ZFP E;  1FBZ A;  3PQZ A;  3VRO A;  1BKM A;  2RSY A;  3HHM B;  5I6V A;  1Y57 A;  1LUN A;  2CI9 A;  1CSZ A;  3CXL A;  4P9V A;  1O43 A;  3HCK A;  1BM2 A;  3S9K A;  1A1C A;  4EIH A;  5CDW A;  1O4N A;  3PSK A;  3UYO A;  1QCF A;  2FO0 A;  1P13 A;  1I3Z A;  1WQU A;  1O45 A;  1XA6 A;  2ECD A;  2IUH A;  3OV1 A;  1A09 A;  2MRJ A;  3MAZ A;  1LKL A;  2KNO A;  4H34 A;  2AUG A;  3N8M A;  1JYR A;  1O4Q A;  1JWO A;  3MXC A;  5DC4 A;  5DF6 A;  2CRH A;  2DCR A;  2LNW A;  1KA7 A;  3OP0 A;  1UUR A;  2PLD A;  1O48 A;  1O47 A;  1CSY A;  1BF5 A;  5HKY A;  1Z3K A;  3VRP A;  1A1E A;  2JYQ A;  2QMS A;  4X6S A;  2CI8 A;  5J3X A;  1OO4 A;  4A4B A;  2DLY A;  3M7F A;  1QAD A;  2EOB A;  1AOU F;  1O4O A;  2IZV A;  1A1B A;  2IUI A;  3T04 A;  3IMJ A;  2C0I A;  4F5A A;  3C7I A;  1AYC A;  3S8L A;  1A07 A;  2HUW A;  2K7A B;  2CIA A;  1M27 A;  3CWG A;  2C0T A;  2ABL A;  3OB2 B;  1MIL A;  4LUE A;  4TZI A;  3N7Y A;  4U17 A;  1FYR A;  3VS0 A;  3EAZ A;  5AXI A;  3VS4 A;  2CR4 A;  1YVL A;  3VRZ A;  1R1Q A;  1TCE A;  1O4P A;  5BO4 A;  3GXW A;  1BMB A;  4E93 A;  1LUI A;  2XP1 A;  4K11 A;  2EO6 A;  2LCT A;  1FHS A;  1O4G A;  5HKW A;  1A08 A;  1FU6 A;  1O46 A;  1MW4 A;  3N84 A;  3IN8 A;  1AD5 A;  1O4R A;  3PSJ A;  4A4C A;  1K9A A;  4U1P A;  2MK2 A;  1LUM A;  1NZL A;  1IS0 A;  2L6K A;  3NHN A;  1AYD A;  5EHP A;  4XZ0 A;  4NWF A;  2CBL A;  3MXY A;  2AOA A;  1R1S A;  1O4M A;  1KC2 A;  2RMX A;  1BFJ A;  3BUW B;  3PLF B;  4D8K A;  1O42 A;  3BUN B;  1JYU A;  3TL0 A;  1HCT B;  2HDX A;  1O4K A;  1D1Z A;  1O4J A;  4OHH A;  3OVE A;  2H46 E;  3BKB A;  1BLK A;  1LCJ A;  4M4Z A;  2CS0 A;  3BUO B;  1RJA A;  3CBL A;  3VS1 A;  3QWY A;  1IJR A;  4K44 A;  3IMD A;  3UF4 A;  3CD3 A;  2H8H A;  1O4E A;  1YVH A;  1RPY A;  2HCK A;  4JGH A;  1BFI A;  1AYB A;  1O4A A;  1O4I A;  4DGX A;  1JYQ A;  1D4W A;  4FBN A;  2HDV A;  2L3T A;  1TZE E;  1O44 A;  3KFJ A;  5D0J A;  2EKX A;  1LCK A;  4F5B A;  3S8N A;  1AB2 A;  1KA6 A;  1FMK A;  5KAZ A;  4FL2 A;  1B47 A;  1SHD A;  1CJ1 A;  5HKZ A;  3VS3 A;  4FL3 A;  1RQQ C;  2EO3 A;  1O41 A;  2Y1M A;  3GXX A;  5EHR A;  4E68 A;  4K2R A;  3US4 A;  2SRC A;  5DC9 A;  2AOB A;  5IBM A;  1CWD L;  4DGP A;  1A81 A;  3VRY A;  4EY0 A;  1G83 A;  2YSX A;  2RVF A;  1O4H A;  1SPR A;  3OB1 B;  5EEQ A;  3VRQ A;  2BBU A;  1SKJ A;  1BKL A;  1O4L A;  1NZV A;  2MRK A;  1AYA A;  2Y1N A;  4OHI A;  1O4B A;  3K2M A;  1SHA A;  4JEG A;  4ROJ A;  2ROR A;  4F59 A;  1QG1 E;  2OZO A;  1D4T A;  2EYZ A;  3VRN A;  2GE9 A;  5GJI A;  4P9Z A;  2Y3A B;  4K45 A;  1F2F A;  3VS7 A;  1BG1 A;  2DM0 A;  3HIZ B;  5DC0 B;  1BLJ A;  2C0O A;  4GWF A;  2DX0 A;  1PIC A;  1Y1U A;  1BHH A;  3BUM B;  3BUX B;  2VIF A;  2LQN A;  2LQW A;  2ETZ A;  1SHB A;  2EL8 A;  2K79 B;  1R1P A;  4H1O A;  1X27 A;  1SPS A;  1O49 A;  1GHU A;  3GQI B;  2EYV A;  3TKZ A;  3ZNI A;  1UUS A;  2YU7 A;  1LKK A;  2MC1 A;  2IUG A;  1AOT F;  4OHD A;  5GJH A;  1NRV A;  2DLZ A;  2KK6 A;  2EU0 A;  1O4C A;  2EYY A;  2PNB A;  4OHE A;  4WWQ A;  2B3O A;  2DVJ A;  3QWX X;  4OHL A;  2SHP A;  2LNX A;  4XZ1 A;  3VS2 A;  2H5K A;  2OQ1 A;  2PLE A;  3VS5 A;  5AUL A;  2HMH A;  1BHF A;  1OPK A;  3S8O A;  1GRI A;  1O4D A;  1HCS B;  3PFV A;  4GPL B;  1H9O A;  1OO3 A;  4NWG A;  4GL9 E;  1F1W A; 
#chains in the Genus database with same CATH topology
 1A1A A;  3EAC A;  3VS6 A;  3WA4 A;  1FU5 A;  1JU5 A;  2GSB A;  1M61 A;  2C9W A;  1OPL A;  4L1B B;  1X6C A;  4JE4 A;  1KSW A;  1X0N A;  2PTK A;  4QSY A;  3PS5 A;  1FBV A;  3VRR A;  2FCI A;  3IN7 A;  3VGO A;  4LUD A;  2MQI A;  5IBS A;  1O4F A;  5EG3 B;  1LUK A;  2L4K A;  2PNA A;  1BHH B;  3PJP A;  1CWE A;  5EEL A;  1ZFP E;  1FBZ A;  3PQZ A;  3VRO A;  1BKM A;  2RSY A;  2LRA A;  3HHM B;  5I6V A;  1Y57 A;  1LUN A;  2CI9 A;  1CSZ A;  3CXL A;  4P9V A;  1O43 A;  3HCK A;  1BM2 A;  3S9K A;  1A1C A;  4EIH A;  5CDW A;  1O4N A;  3PSK A;  3UYO A;  1QCF A;  2FO0 A;  1P13 A;  1I3Z A;  1WQU A;  1O45 A;  1XA6 A;  2ECD A;  2IUH A;  3OV1 A;  1A09 A;  2MRJ A;  3MAZ A;  1LKL A;  2KNO A;  4H34 A;  2AUG A;  3N8M A;  1JYR A;  1O4Q A;  1JWO A;  3MXC A;  5DC4 A;  5DF6 A;  2CRH A;  2DCR A;  2LNW A;  1KA7 A;  3OP0 A;  1UUR A;  2PLD A;  1O48 A;  1O47 A;  1CSY A;  1BF5 A;  5HKY A;  1Z3K A;  3VRP A;  1A1E A;  2JYQ A;  2QMS A;  4X6S A;  2CI8 A;  5J3X A;  1OO4 A;  4A4B A;  2DLY A;  3M7F A;  1QAD A;  2EOB A;  1AOU F;  1O4O A;  2IZV A;  1A1B A;  2IUI A;  3T04 A;  3IMJ A;  2C0I A;  4F5A A;  3C7I A;  1AYC A;  3S8L A;  1A07 A;  2HUW A;  2K7A B;  2CIA A;  1M27 A;  3CWG A;  2C0T A;  2ABL A;  3OB2 B;  1MIL A;  4LUE A;  4TZI A;  3N7Y A;  4U17 A;  1FYR A;  3VS0 A;  3EAZ A;  5AXI A;  3VS4 A;  2CR4 A;  1YVL A;  3VRZ A;  1R1Q A;  1TCE A;  1O4P A;  5BO4 A;  3GXW A;  1BMB A;  4E93 A;  1LUI A;  2XP1 A;  4K11 A;  2EO6 A;  2LCT A;  1FHS A;  1O4G A;  5HKW A;  1A08 A;  1FU6 A;  1O46 A;  1MW4 A;  3N84 A;  3IN8 A;  1AD5 A;  1O4R A;  3PSJ A;  4A4C A;  1K9A A;  4U1P A;  2MK2 A;  1LUM A;  1NZL A;  1IS0 A;  2L6K A;  3NHN A;  1AYD A;  5EHP A;  4XZ0 A;  4NWF A;  2CBL A;  3MXY A;  2AOA A;  1R1S A;  1O4M A;  1KC2 A;  2RMX A;  1BFJ A;  3BUW B;  3PLF B;  4D8K A;  1O42 A;  3BUN B;  1JYU A;  3TL0 A;  1HCT B;  2HDX A;  1O4K A;  1D1Z A;  1O4J A;  4OHH A;  3OVE A;  2H46 E;  3BKB A;  1BLK A;  1LCJ A;  4M4Z A;  2CS0 A;  3BUO B;  1RJA A;  3CBL A;  3VS1 A;  3QWY A;  1IJR A;  4K44 A;  3IMD A;  3UF4 A;  3CD3 A;  2H8H A;  1O4E A;  1YVH A;  1RPY A;  2HCK A;  4JGH A;  1BFI A;  1AYB A;  1O4A A;  1O4I A;  4DGX A;  1JYQ A;  1D4W A;  4FBN A;  2HDV A;  2L3T A;  1TZE E;  1O44 A;  3KFJ A;  5D0J A;  2EKX A;  1LCK A;  4F5B A;  3S8N A;  1AB2 A;  1KA6 A;  1FMK A;  5KAZ A;  4FL2 A;  1B47 A;  1SHD A;  1CJ1 A;  5HKZ A;  3VS3 A;  4FL3 A;  1RQQ C;  2EO3 A;  1O41 A;  2Y1M A;  3GXX A;  5EHR A;  4E68 A;  4K2R A;  3US4 A;  2SRC A;  5DC9 A;  2AOB A;  5IBM A;  1CWD L;  4DGP A;  1A81 A;  3VRY A;  4EY0 A;  1G83 A;  2YSX A;  2RVF A;  1O4H A;  1SPR A;  3OB1 B;  5EEQ A;  3VRQ A;  2BBU A;  1SKJ A;  1BKL A;  1O4L A;  1NZV A;  2MRK A;  1AYA A;  2KGY A;  2Y1N A;  4OHI A;  1O4B A;  3K2M A;  1SHA A;  4JEG A;  4ROJ A;  2ROR A;  4F59 A;  1QG1 E;  2OZO A;  3LYV A;  1D4T A;  2EYZ A;  3VRN A;  2GE9 A;  5GJI A;  4P9Z A;  2Y3A B;  4K45 A;  1F2F A;  3VS7 A;  1BG1 A;  2DM0 A;  3HIZ B;  5DC0 B;  1BLJ A;  2C0O A;  4GWF A;  2DX0 A;  1PIC A;  1Y1U A;  1BHH A;  3BUM B;  3BUX B;  2VIF A;  2LQN A;  2LQW A;  2ETZ A;  1SHB A;  2EL8 A;  2K79 B;  1R1P A;  4H1O A;  1X27 A;  1SPS A;  1O49 A;  1GHU A;  3GQI B;  2EYV A;  3TKZ A;  3ZNI A;  1UUS A;  2YU7 A;  1LKK A;  2MC1 A;  2IUG A;  1AOT F;  4OHD A;  5GJH A;  1NRV A;  2DLZ A;  2KK6 A;  2EU0 A;  1O4C A;  2EYY A;  2PNB A;  4OHE A;  4WWQ A;  2B3O A;  2DVJ A;  3QWX X;  3K2T A;  4OHL A;  2SHP A;  2LNX A;  4XZ1 A;  3VS2 A;  2H5K A;  2OQ1 A;  2PLE A;  3VS5 A;  5AUL A;  2HMH A;  1BHF A;  1OPK A;  3S8O A;  1GRI A;  1O4D A;  1HCS B;  3PFV A;  4GPL B;  1H9O A;  1OO3 A;  4NWG A;  4GL9 E;  1F1W A; 
#chains in the Genus database with same CATH homology
 1A1A A;  3EAC A;  3VS6 A;  3WA4 A;  1FU5 A;  1JU5 A;  2GSB A;  1M61 A;  2C9W A;  1OPL A;  4L1B B;  1X6C A;  4JE4 A;  1KSW A;  1X0N A;  2PTK A;  4QSY A;  3PS5 A;  1FBV A;  3VRR A;  2FCI A;  3IN7 A;  3VGO A;  4LUD A;  2MQI A;  5IBS A;  1O4F A;  5EG3 B;  1LUK A;  2L4K A;  2PNA A;  1BHH B;  3PJP A;  1CWE A;  5EEL A;  1ZFP E;  1FBZ A;  3PQZ A;  3VRO A;  1BKM A;  2RSY A;  3HHM B;  5I6V A;  1Y57 A;  1LUN A;  2CI9 A;  1CSZ A;  3CXL A;  4P9V A;  1O43 A;  3HCK A;  1BM2 A;  3S9K A;  1A1C A;  4EIH A;  5CDW A;  1O4N A;  3PSK A;  3UYO A;  1QCF A;  2FO0 A;  1P13 A;  1I3Z A;  1WQU A;  1O45 A;  1XA6 A;  2ECD A;  2IUH A;  3OV1 A;  1A09 A;  2MRJ A;  3MAZ A;  1LKL A;  2KNO A;  4H34 A;  2AUG A;  3N8M A;  1JYR A;  1O4Q A;  1JWO A;  3MXC A;  5DC4 A;  5DF6 A;  2CRH A;  2DCR A;  2LNW A;  1KA7 A;  3OP0 A;  1UUR A;  2PLD A;  1O48 A;  1O47 A;  1CSY A;  1BF5 A;  5HKY A;  1Z3K A;  3VRP A;  1A1E A;  2JYQ A;  2QMS A;  4X6S A;  2CI8 A;  5J3X A;  1OO4 A;  4A4B A;  2DLY A;  3M7F A;  1QAD A;  2EOB A;  1AOU F;  1O4O A;  2IZV A;  1A1B A;  2IUI A;  3T04 A;  3IMJ A;  2C0I A;  4F5A A;  3C7I A;  1AYC A;  3S8L A;  1A07 A;  2HUW A;  2K7A B;  2CIA A;  1M27 A;  3CWG A;  2C0T A;  2ABL A;  3OB2 B;  1MIL A;  4LUE A;  4TZI A;  3N7Y A;  4U17 A;  1FYR A;  3VS0 A;  3EAZ A;  5AXI A;  3VS4 A;  2CR4 A;  1YVL A;  3VRZ A;  1R1Q A;  1TCE A;  1O4P A;  5BO4 A;  3GXW A;  1BMB A;  4E93 A;  1LUI A;  2XP1 A;  4K11 A;  2EO6 A;  2LCT A;  1FHS A;  1O4G A;  5HKW A;  1A08 A;  1FU6 A;  1O46 A;  1MW4 A;  3N84 A;  3IN8 A;  1AD5 A;  1O4R A;  3PSJ A;  4A4C A;  1K9A A;  4U1P A;  2MK2 A;  1LUM A;  1NZL A;  1IS0 A;  2L6K A;  3NHN A;  1AYD A;  5EHP A;  4XZ0 A;  4NWF A;  2CBL A;  3MXY A;  2AOA A;  1R1S A;  1O4M A;  1KC2 A;  2RMX A;  1BFJ A;  3BUW B;  3PLF B;  4D8K A;  1O42 A;  3BUN B;  1JYU A;  3TL0 A;  1HCT B;  2HDX A;  1O4K A;  1D1Z A;  1O4J A;  4OHH A;  3OVE A;  2H46 E;  3BKB A;  1BLK A;  1LCJ A;  4M4Z A;  2CS0 A;  3BUO B;  1RJA A;  3CBL A;  3VS1 A;  3QWY A;  1IJR A;  4K44 A;  3IMD A;  3UF4 A;  3CD3 A;  2H8H A;  1O4E A;  1YVH A;  1RPY A;  2HCK A;  4JGH A;  1BFI A;  1AYB A;  1O4A A;  1O4I A;  4DGX A;  1JYQ A;  1D4W A;  4FBN A;  2HDV A;  2L3T A;  1TZE E;  1O44 A;  3KFJ A;  5D0J A;  2EKX A;  1LCK A;  4F5B A;  3S8N A;  1AB2 A;  1KA6 A;  1FMK A;  5KAZ A;  4FL2 A;  1B47 A;  1SHD A;  1CJ1 A;  5HKZ A;  3VS3 A;  4FL3 A;  1RQQ C;  2EO3 A;  1O41 A;  2Y1M A;  3GXX A;  5EHR A;  4E68 A;  4K2R A;  3US4 A;  2SRC A;  5DC9 A;  2AOB A;  5IBM A;  1CWD L;  4DGP A;  1A81 A;  3VRY A;  4EY0 A;  1G83 A;  2YSX A;  2RVF A;  1O4H A;  1SPR A;  3OB1 B;  5EEQ A;  3VRQ A;  2BBU A;  1SKJ A;  1BKL A;  1O4L A;  1NZV A;  2MRK A;  1AYA A;  2Y1N A;  4OHI A;  1O4B A;  3K2M A;  1SHA A;  4JEG A;  4ROJ A;  2ROR A;  4F59 A;  1QG1 E;  2OZO A;  1D4T A;  2EYZ A;  3VRN A;  2GE9 A;  5GJI A;  4P9Z A;  2Y3A B;  4K45 A;  1F2F A;  3VS7 A;  1BG1 A;  2DM0 A;  3HIZ B;  5DC0 B;  1BLJ A;  2C0O A;  4GWF A;  2DX0 A;  1PIC A;  1Y1U A;  1BHH A;  3BUM B;  3BUX B;  2VIF A;  2LQN A;  2LQW A;  2ETZ A;  1SHB A;  2EL8 A;  2K79 B;  1R1P A;  4H1O A;  1X27 A;  1SPS A;  1O49 A;  1GHU A;  3GQI B;  2EYV A;  3TKZ A;  3ZNI A;  1UUS A;  2YU7 A;  1LKK A;  2MC1 A;  2IUG A;  1AOT F;  4OHD A;  5GJH A;  1NRV A;  2DLZ A;  2KK6 A;  2EU0 A;  1O4C A;  2EYY A;  2PNB A;  4OHE A;  4WWQ A;  2B3O A;  2DVJ A;  3QWX X;  4OHL A;  2SHP A;  2LNX A;  4XZ1 A;  3VS2 A;  2H5K A;  2OQ1 A;  2PLE A;  3VS5 A;  5AUL A;  2HMH A;  1BHF A;  1OPK A;  3S8O A;  1GRI A;  1O4D A;  1HCS B;  3PFV A;  4GPL B;  1H9O A;  1OO3 A;  4NWG A;  4GL9 E;  1F1W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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