1IS0A

Crystal structure of a complex of the src sh2 domain with conformationally constrained peptide inhibitor
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
102
structure length
102
Chain Sequence
EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Rous sarcoma virus
molecule keywords Tyrosine-protein kinase transforming protein SRC
total genus 27
structure length 102
sequence length 102
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2001-11-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1is0A00
3S8NA 3UF4A 1KA6A 1O4LA 2VIFA 4H34A 2C0TA 2K7AB 1O4FA 1LCJA 2LNWA 2HDXA 1BKLA 2RORA 3CD3A 1JYRA 1BF5A 2AOBA 3HCKA 3OP0A 3IN8A 3VRPA 1Y1UA 4P9VA 3S8OA 2IZVA 3VGOA 1O4BA 1NZLA 2RMXA 1G83A 1SHDA 4M4ZA 2C9WA 1A08A 2DCRA 4H1OA 3QWXX 3OB2B 3PSKA 1CWEA 1OPLA 1PICA 1QG1E 1D4TA 1JYUA 1AYAA 2EU0A 5DF6A 3K2MA 1YVLA 4F59A 3MAZA 4F5BA 1UURA 3MXYA 4XZ0A 1AYCA 4EY0A 4A4BA 2HCKA 4FL3A 1KA7A 4U1PA 1GRIA 4FL2A 4OHHA 1OO3A 5HKWA 1X0NA 2L6KA 1O4RA 3NHNA 4F5AA 1A1AA 1GHUA 1SKJA 2Y1NA 2MQIA 1O4JA 3BUWB 4L1BB 1H9OA 1FU5A 1Z3KA 1FU6A 1MILA 1O44A 2CIAA 1CWDL 2DM0A 2ABLA 2QMSA 1FHSA 2EYYA 1AD5A 5BO4A 1O49A 1KSWA 2EYVA 3M7FA 4OHLA 5EHPA 2PTKA 1CJ1A 1O42A 1RPYA 1F2FA 4E93A 4A4CA 3TKZA 1XA6A 4X6SA 3N8MA 5GJHA 3VS4A 1SPSA 5GJIA 1BFJA 4TZIA 1BHHA 2EO3A 4P9ZA 2H46E 5CDWA 1O43A 4NWFA 1M27A 2AUGA 4JE4A 1WQUA 5KAZA 4FBNA 2EKXA 2DVJA 1X27A 3VS5A 2KNOA 1LUMA 2FCIA 1NRVA 2OQ1A 2LQWA 1M61A 1JWOA 3QWYA 4GWFA 4DGPA 5EG3B 4JEGA 1TCEA 1A1CA 1SHAA 2GE9A 3VRYA 1HCTB 4LUEA 2XP1A 1OPKA 1CSYA 1BHHB 2PLEA 3MXCA 3US4A 3VS1A 1F1WA 2H8HA 3ZNIA 1AOTF 2IUHA 4K44A 4ROJA 1R1SA 1D4WA 4K45A 2AOAA 3VRNA 1A09A 5DC4A 1O45A 1KC2A 3BUMB 1O4HA 2ETZA 2MK2A 2MRKA 1R1QA 1AYBA 3PS5A 1LKKA 1O4GA 2PNBA 3WA4A 3VS6A 3PFVA 4NWGA 3KFJA 1LKLA 1QADA 3VS2A 5AXIA 1JU5A 2CI8A 3BKBA 1O4CA 2Y1MA 1AB2A 1B47A 3BUNB 2HMHA 1AYDA 3HIZB 3S9KA 2MC1A 1FBVA 3VRZA 2DX0A 3S8LA 3IN7A 2LCTA 3EACA 1FMKA 3VS3A 2PLDA 5EHRA 1MW4A 1IJRA 1UUSA 5I6VA 2L4KA 3VS7A 1A1BA 5IBMA 1K9AA 3T04A 1TZEE 2PNAA 2SHPA 2B3OA 4WWQA 3C7IA 4JGHA 4DGXA 5DC0B 2Y3AB 3UYOA 5IBSA 2EOBA 1FYRA 3HHMB 3PQZA 2CRHA 3CWGA 1LUKA 2RSYA 3PLFB 3VRQA 2EL8A 4OHIA 3PSJA 3IMDA 4U17A 1A1EA 2HUWA 1IS0A 2IUGA 1QCFA 1RQQC 4QSYA 5EELA 5HKZA 1YVHA 3OV1A 1BLJA 2RVFA 3IMJA 1BHFA 1I3ZA 1LCKA 5HKYA 1O41A 2OZOA 1LUNA 4E68A 1BM2A 4LUDA 1P13A 1ZFPE 2CBLA 5EEQA 3OVEA 1O4QA 2LNXA 1O4AA 2SRCA 2EO6A 5J3XA 2EYZA 3PJPA 2C0OA 1Y57A 2DLZA 3BUXB 1O4MA 1R1PA 1O4OA 1SPRA 3N84A 1O4NA 4K11A 1X6CA 3VS0A 3OB1B 1O48A 3GQIB 2FO0A 2YU7A 3CXLA 2K79B 4GPLB 5AULA 1CSZA 3N7YA 1BG1A 1A81A 2CS0A 1NZVA 2HDVA 1O4EA 3TL0A 2DLYA 2KK6A 3BUOB 4XZ1A 2ECDA 2CR4A 2YSXA 4GL9E 2JYQA 1O4DA 1BLKA 1FBZA 4K2RA 1O4KA 1OO4A 3VROA 1BFIA 2IUIA 5DC9A 2GSBA 2L3TA 1SHBA 3EAZA 4D8KA 1HCSB 1D1ZA 3GXWA 1BMBA 1O46A 3CBLA 2BBUA 1O47A 3GXXA 1RJAA 1JYQA 1O4PA 4EIHA 2C0IA 4OHDA 1O4IA 1A07A 2LQNA 2MRJA 1LUIA 1BKMA 2H5KA 1AOUF 3VRRA 5D0JA 2CI9A 4OHEA
chains in the Genus database with same CATH superfamily
3S8NA 3UF4A 1KA6A 1O4LA 2VIFA 4H34A 2C0TA 2K7AB 1O4FA 1LCJA 2LNWA 2HDXA 1BKLA 2RORA 3CD3A 1JYRA 1BF5A 2AOBA 3HCKA 3OP0A 3IN8A 3VRPA 1Y1UA 4P9VA 3S8OA 2IZVA 3VGOA 1O4BA 1NZLA 2RMXA 1G83A 1SHDA 4M4ZA 2C9WA 1A08A 2DCRA 4H1OA 3QWXX 3OB2B 3PSKA 1CWEA 1OPLA 1PICA 1QG1E 1D4TA 1JYUA 1AYAA 2EU0A 5DF6A 3K2MA 1YVLA 4F59A 3MAZA 4F5BA 1UURA 3MXYA 4XZ0A 1AYCA 4EY0A 4A4BA 2HCKA 4FL3A 1KA7A 4U1PA 1GRIA 4FL2A 4OHHA 1OO3A 5HKWA 1X0NA 2L6KA 1O4RA 3NHNA 4F5AA 1A1AA 1GHUA 1SKJA 2Y1NA 2MQIA 1O4JA 3BUWB 4L1BB 1H9OA 1FU5A 1Z3KA 1FU6A 1MILA 1O44A 2CIAA 1CWDL 2DM0A 2ABLA 2QMSA 1FHSA 2EYYA 1AD5A 5BO4A 1O49A 1KSWA 2LRAA 2EYVA 3M7FA 4OHLA 5EHPA 2PTKA 3LYVA 1CJ1A 1O42A 1RPYA 1F2FA 4E93A 4A4CA 3TKZA 1XA6A 4X6SA 3N8MA 5GJHA 3VS4A 1SPSA 5GJIA 1BFJA 4TZIA 1BHHA 2EO3A 4P9ZA 2H46E 5CDWA 1O43A 4NWFA 1M27A 2AUGA 4JE4A 1WQUA 5KAZA 4FBNA 2EKXA 2DVJA 1X27A 3VS5A 2KNOA 1LUMA 2FCIA 1NRVA 2OQ1A 2LQWA 1M61A 1JWOA 3QWYA 4GWFA 4DGPA 5EG3B 4JEGA 1TCEA 1A1CA 1SHAA 2GE9A 3VRYA 1HCTB 4LUEA 2XP1A 1OPKA 1CSYA 1BHHB 2PLEA 3MXCA 3US4A 3VS1A 1F1WA 2H8HA 3ZNIA 1AOTF 2IUHA 4K44A 4ROJA 1R1SA 1D4WA 4K45A 2AOAA 3VRNA 1A09A 5DC4A 1O45A 1KC2A 3BUMB 1O4HA 2ETZA 2MK2A 2MRKA 1R1QA 1AYBA 3PS5A 1LKKA 1O4GA 2PNBA 3WA4A 3VS6A 3PFVA 4NWGA 3KFJA 1LKLA 1QADA 3VS2A 5AXIA 1JU5A 2CI8A 3BKBA 1O4CA 2Y1MA 1AB2A 1B47A 3BUNB 2HMHA 1AYDA 3HIZB 3S9KA 2MC1A 1FBVA 3VRZA 2DX0A 3S8LA 3IN7A 2LCTA 3EACA 1FMKA 3VS3A 2PLDA 5EHRA 1MW4A 1IJRA 1UUSA 5I6VA 2L4KA 3VS7A 1A1BA 5IBMA 1K9AA 3T04A 1TZEE 2PNAA 2SHPA 2B3OA 4WWQA 3C7IA 4JGHA 4DGXA 5DC0B 2Y3AB 3UYOA 5IBSA 2EOBA 1FYRA 3HHMB 3PQZA 2CRHA 3CWGA 1LUKA 2RSYA 3PLFB 3VRQA 2EL8A 4OHIA 3PSJA 3IMDA 4U17A 1A1EA 2HUWA 1IS0A 2IUGA 1QCFA 1RQQC 4QSYA 5EELA 5HKZA 1YVHA 3OV1A 1BLJA 2RVFA 3IMJA 3K2TA 1BHFA 1I3ZA 1LCKA 5HKYA 1O41A 2OZOA 1LUNA 4E68A 1BM2A 4LUDA 1P13A 1ZFPE 2CBLA 5EEQA 3OVEA 1O4QA 2LNXA 1O4AA 2SRCA 2EO6A 5J3XA 2EYZA 3PJPA 2C0OA 1Y57A 2DLZA 3BUXB 1O4MA 1R1PA 1O4OA 1SPRA 3N84A 1O4NA 4K11A 1X6CA 3VS0A 3OB1B 1O48A 3GQIB 2FO0A 2YU7A 3CXLA 2K79B 4GPLB 5AULA 1CSZA 3N7YA 1BG1A 1A81A 2CS0A 1NZVA 2HDVA 1O4EA 3TL0A 2DLYA 2KK6A 3BUOB 4XZ1A 2ECDA 2CR4A 2YSXA 4GL9E 2JYQA 1O4DA 1BLKA 1FBZA 4K2RA 1O4KA 1OO4A 3VROA 1BFIA 2IUIA 2KGYA 5DC9A 2GSBA 2L3TA 1SHBA 3EAZA 4D8KA 1HCSB 1D1ZA 3GXWA 1BMBA 1O46A 3CBLA 2BBUA 1O47A 3GXXA 1RJAA 1JYQA 1O4PA 4EIHA 2C0IA 4OHDA 1O4IA 1A07A 2LQNA 2MRJA 1LUIA 1BKMA 2H5KA 1AOUF 3VRRA 5D0JA 2CI9A 4OHEA
chains in the Genus database with same CATH topology
3S8NA 3UF4A 1KA6A 1O4LA 2VIFA 4H34A 2C0TA 2K7AB 1O4FA 1LCJA 2LNWA 2HDXA 1BKLA 2RORA 3CD3A 1JYRA 1BF5A 2AOBA 3HCKA 3OP0A 3IN8A 3VRPA 1Y1UA 4P9VA 3S8OA 2IZVA 3VGOA 1O4BA 1NZLA 2RMXA 1G83A 1SHDA 4M4ZA 2C9WA 1A08A 2DCRA 4H1OA 3QWXX 3OB2B 3PSKA 1CWEA 1OPLA 1PICA 1QG1E 1D4TA 1JYUA 1AYAA 2EU0A 5DF6A 3K2MA 1YVLA 4F59A 3MAZA 4F5BA 1UURA 3MXYA 4XZ0A 1AYCA 4EY0A 4A4BA 2HCKA 4FL3A 1KA7A 4U1PA 1GRIA 4FL2A 4OHHA 1OO3A 5HKWA 1X0NA 2L6KA 1O4RA 3NHNA 4F5AA 1A1AA 1GHUA 1SKJA 2Y1NA 2MQIA 1O4JA 3BUWB 4L1BB 1H9OA 1FU5A 1Z3KA 1FU6A 1MILA 1O44A 2CIAA 1CWDL 2DM0A 2ABLA 2QMSA 1FHSA 2EYYA 1AD5A 5BO4A 1O49A 1KSWA 2EYVA 3M7FA 4OHLA 5EHPA 2PTKA 1CJ1A 1O42A 1RPYA 1F2FA 4E93A 4A4CA 3TKZA 1XA6A 4X6SA 3N8MA 5GJHA 3VS4A 1SPSA 5GJIA 1BFJA 4TZIA 1BHHA 2EO3A 4P9ZA 2H46E 5CDWA 1O43A 4NWFA 1M27A 2AUGA 4JE4A 1WQUA 5KAZA 4FBNA 2EKXA 2DVJA 1X27A 3VS5A 2KNOA 1LUMA 2FCIA 1NRVA 2OQ1A 2LQWA 1M61A 1JWOA 3QWYA 4GWFA 4DGPA 5EG3B 4JEGA 1TCEA 1A1CA 1SHAA 2GE9A 3VRYA 1HCTB 4LUEA 2XP1A 1OPKA 1CSYA 1BHHB 2PLEA 3MXCA 3US4A 3VS1A 1F1WA 2H8HA 3ZNIA 1AOTF 2IUHA 4K44A 4ROJA 1R1SA 1D4WA 4K45A 2AOAA 3VRNA 1A09A 5DC4A 1O45A 1KC2A 3BUMB 1O4HA 2ETZA 2MK2A 2MRKA 1R1QA 1AYBA 3PS5A 1LKKA 1O4GA 2PNBA 3WA4A 3VS6A 3PFVA 4NWGA 3KFJA 1LKLA 1QADA 3VS2A 5AXIA 1JU5A 2CI8A 3BKBA 1O4CA 2Y1MA 1AB2A 1B47A 3BUNB 2HMHA 1AYDA 3HIZB 3S9KA 2MC1A 1FBVA 3VRZA 2DX0A 3S8LA 3IN7A 2LCTA 3EACA 1FMKA 3VS3A 2PLDA 5EHRA 1MW4A 1IJRA 1UUSA 5I6VA 2L4KA 3VS7A 1A1BA 5IBMA 1K9AA 3T04A 1TZEE 2PNAA 2SHPA 2B3OA 4WWQA 3C7IA 4JGHA 4DGXA 5DC0B 2Y3AB 3UYOA 5IBSA 2EOBA 1FYRA 3HHMB 3PQZA 2CRHA 3CWGA 1LUKA 2RSYA 3PLFB 3VRQA 2EL8A 4OHIA 3PSJA 3IMDA 4U17A 1A1EA 2HUWA 1IS0A 2IUGA 1QCFA 1RQQC 4QSYA 5EELA 5HKZA 1YVHA 3OV1A 1BLJA 2RVFA 3IMJA 1BHFA 1I3ZA 1LCKA 5HKYA 1O41A 2OZOA 1LUNA 4E68A 1BM2A 4LUDA 1P13A 1ZFPE 2CBLA 5EEQA 3OVEA 1O4QA 2LNXA 1O4AA 2SRCA 2EO6A 5J3XA 2EYZA 3PJPA 2C0OA 1Y57A 2DLZA 3BUXB 1O4MA 1R1PA 1O4OA 1SPRA 3N84A 1O4NA 4K11A 1X6CA 3VS0A 3OB1B 1O48A 3GQIB 2FO0A 2YU7A 3CXLA 2K79B 4GPLB 5AULA 1CSZA 3N7YA 1BG1A 1A81A 2CS0A 1NZVA 2HDVA 1O4EA 3TL0A 2DLYA 2KK6A 3BUOB 4XZ1A 2ECDA 2CR4A 2YSXA 4GL9E 2JYQA 1O4DA 1BLKA 1FBZA 4K2RA 1O4KA 1OO4A 3VROA 1BFIA 2IUIA 5DC9A 2GSBA 2L3TA 1SHBA 3EAZA 4D8KA 1HCSB 1D1ZA 3GXWA 1BMBA 1O46A 3CBLA 2BBUA 1O47A 3GXXA 1RJAA 1JYQA 1O4PA 4EIHA 2C0IA 4OHDA 1O4IA 1A07A 2LQNA 2MRJA 1LUIA 1BKMA 2H5KA 1AOUF 3VRRA 5D0JA 2CI9A 4OHEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S8N A;  3UF4 A;  1KA6 A;  1O4L A;  2VIF A;  4H34 A;  2C0T A;  2K7A B;  1O4F A;  1LCJ A;  2LNW A;  2HDX A;  1BKL A;  2ROR A;  3CD3 A;  1JYR A;  1BF5 A;  2AOB A;  3HCK A;  3OP0 A;  3IN8 A;  3VRP A;  1Y1U A;  4P9V A;  3S8O A;  2IZV A;  3VGO A;  1O4B A;  1NZL A;  2RMX A;  1G83 A;  1SHD A;  4M4Z A;  2C9W A;  1A08 A;  2DCR A;  4H1O A;  3QWX X;  3OB2 B;  3PSK A;  1CWE A;  1OPL A;  1PIC A;  1QG1 E;  1D4T A;  1JYU A;  1AYA A;  2EU0 A;  5DF6 A;  3K2M A;  1YVL A;  4F59 A;  3MAZ A;  4F5B A;  1UUR A;  3MXY A;  4XZ0 A;  1AYC A;  4EY0 A;  4A4B A;  2HCK A;  4FL3 A;  1KA7 A;  4U1P A;  1GRI A;  4FL2 A;  4OHH A;  1OO3 A;  5HKW A;  1X0N A;  2L6K A;  1O4R A;  3NHN A;  4F5A A;  1A1A A;  1GHU A;  1SKJ A;  2Y1N A;  2MQI A;  1O4J A;  3BUW B;  4L1B B;  1H9O A;  1FU5 A;  1Z3K A;  1FU6 A;  1MIL A;  1O44 A;  2CIA A;  1CWD L;  2DM0 A;  2ABL A;  2QMS A;  1FHS A;  2EYY A;  1AD5 A;  5BO4 A;  1O49 A;  1KSW A;  2EYV A;  3M7F A;  4OHL A;  5EHP A;  2PTK A;  1CJ1 A;  1O42 A;  1RPY A;  1F2F A;  4E93 A;  4A4C A;  3TKZ A;  1XA6 A;  4X6S A;  3N8M A;  5GJH A;  3VS4 A;  1SPS A;  5GJI A;  1BFJ A;  4TZI A;  1BHH A;  2EO3 A;  4P9Z A;  2H46 E;  5CDW A;  1O43 A;  4NWF A;  1M27 A;  2AUG A;  4JE4 A;  1WQU A;  5KAZ A;  4FBN A;  2EKX A;  2DVJ A;  1X27 A;  3VS5 A;  2KNO A;  1LUM A;  2FCI A;  1NRV A;  2OQ1 A;  2LQW A;  1M61 A;  1JWO A;  3QWY A;  4GWF A;  4DGP A;  5EG3 B;  4JEG A;  1TCE A;  1A1C A;  1SHA A;  2GE9 A;  3VRY A;  1HCT B;  4LUE A;  2XP1 A;  1OPK A;  1CSY A;  1BHH B;  2PLE A;  3MXC A;  3US4 A;  3VS1 A;  1F1W A;  2H8H A;  3ZNI A;  1AOT F;  2IUH A;  4K44 A;  4ROJ A;  1R1S A;  1D4W A;  4K45 A;  2AOA A;  3VRN A;  1A09 A;  5DC4 A;  1O45 A;  1KC2 A;  3BUM B;  1O4H A;  2ETZ A;  2MK2 A;  2MRK A;  1R1Q A;  1AYB A;  3PS5 A;  1LKK A;  1O4G A;  2PNB A;  3WA4 A;  3VS6 A;  3PFV A;  4NWG A;  3KFJ A;  1LKL A;  1QAD A;  3VS2 A;  5AXI A;  1JU5 A;  2CI8 A;  3BKB A;  1O4C A;  2Y1M A;  1AB2 A;  1B47 A;  3BUN B;  2HMH A;  1AYD A;  3HIZ B;  3S9K A;  2MC1 A;  1FBV A;  3VRZ A;  2DX0 A;  3S8L A;  3IN7 A;  2LCT A;  3EAC A;  1FMK A;  3VS3 A;  2PLD A;  5EHR A;  1MW4 A;  1IJR A;  1UUS A;  5I6V A;  2L4K A;  3VS7 A;  1A1B A;  5IBM A;  1K9A A;  3T04 A;  1TZE E;  2PNA A;  2SHP A;  2B3O A;  4WWQ A;  3C7I A;  4JGH A;  4DGX A;  5DC0 B;  2Y3A B;  3UYO A;  5IBS A;  2EOB A;  1FYR A;  3HHM B;  3PQZ A;  2CRH A;  3CWG A;  1LUK A;  2RSY A;  3PLF B;  3VRQ A;  2EL8 A;  4OHI A;  3PSJ A;  3IMD A;  4U17 A;  1A1E A;  2HUW A;  1IS0 A;  2IUG A;  1QCF A;  1RQQ C;  4QSY A;  5EEL A;  5HKZ A;  1YVH A;  3OV1 A;  1BLJ A;  2RVF A;  3IMJ A;  1BHF A;  1I3Z A;  1LCK A;  5HKY A;  1O41 A;  2OZO A;  1LUN A;  4E68 A;  1BM2 A;  4LUD A;  1P13 A;  1ZFP E;  2CBL A;  5EEQ A;  3OVE A;  1O4Q A;  2LNX A;  1O4A A;  2SRC A;  2EO6 A;  5J3X A;  2EYZ A;  3PJP A;  2C0O A;  1Y57 A;  2DLZ A;  3BUX B;  1O4M A;  1R1P A;  1O4O A;  1SPR A;  3N84 A;  1O4N A;  4K11 A;  1X6C A;  3VS0 A;  3OB1 B;  1O48 A;  3GQI B;  2FO0 A;  2YU7 A;  3CXL A;  2K79 B;  4GPL B;  5AUL A;  1CSZ A;  3N7Y A;  1BG1 A;  1A81 A;  2CS0 A;  1NZV A;  2HDV A;  1O4E A;  3TL0 A;  2DLY A;  2KK6 A;  3BUO B;  4XZ1 A;  2ECD A;  2CR4 A;  2YSX A;  4GL9 E;  2JYQ A;  1O4D A;  1BLK A;  1FBZ A;  4K2R A;  1O4K A;  1OO4 A;  3VRO A;  1BFI A;  2IUI A;  5DC9 A;  2GSB A;  2L3T A;  1SHB A;  3EAZ A;  4D8K A;  1HCS B;  1D1Z A;  3GXW A;  1BMB A;  1O46 A;  3CBL A;  2BBU A;  1O47 A;  3GXX A;  1RJA A;  1JYQ A;  1O4P A;  4EIH A;  2C0I A;  4OHD A;  1O4I A;  1A07 A;  2LQN A;  2MRJ A;  1LUI A;  1BKM A;  2H5K A;  1AOU F;  3VRR A;  5D0J A;  2CI9 A;  4OHE A; 
#chains in the Genus database with same CATH topology
 3S8N A;  3UF4 A;  1KA6 A;  1O4L A;  2VIF A;  4H34 A;  2C0T A;  2K7A B;  1O4F A;  1LCJ A;  2LNW A;  2HDX A;  1BKL A;  2ROR A;  3CD3 A;  1JYR A;  1BF5 A;  2AOB A;  3HCK A;  3OP0 A;  3IN8 A;  3VRP A;  1Y1U A;  4P9V A;  3S8O A;  2IZV A;  3VGO A;  1O4B A;  1NZL A;  2RMX A;  1G83 A;  1SHD A;  4M4Z A;  2C9W A;  1A08 A;  2DCR A;  4H1O A;  3QWX X;  3OB2 B;  3PSK A;  1CWE A;  1OPL A;  1PIC A;  1QG1 E;  1D4T A;  1JYU A;  1AYA A;  2EU0 A;  5DF6 A;  3K2M A;  1YVL A;  4F59 A;  3MAZ A;  4F5B A;  1UUR A;  3MXY A;  4XZ0 A;  1AYC A;  4EY0 A;  4A4B A;  2HCK A;  4FL3 A;  1KA7 A;  4U1P A;  1GRI A;  4FL2 A;  4OHH A;  1OO3 A;  5HKW A;  1X0N A;  2L6K A;  1O4R A;  3NHN A;  4F5A A;  1A1A A;  1GHU A;  1SKJ A;  2Y1N A;  2MQI A;  1O4J A;  3BUW B;  4L1B B;  1H9O A;  1FU5 A;  1Z3K A;  1FU6 A;  1MIL A;  1O44 A;  2CIA A;  1CWD L;  2DM0 A;  2ABL A;  2QMS A;  1FHS A;  2EYY A;  1AD5 A;  5BO4 A;  1O49 A;  1KSW A;  2LRA A;  2EYV A;  3M7F A;  4OHL A;  5EHP A;  2PTK A;  3LYV A;  1CJ1 A;  1O42 A;  1RPY A;  1F2F A;  4E93 A;  4A4C A;  3TKZ A;  1XA6 A;  4X6S A;  3N8M A;  5GJH A;  3VS4 A;  1SPS A;  5GJI A;  1BFJ A;  4TZI A;  1BHH A;  2EO3 A;  4P9Z A;  2H46 E;  5CDW A;  1O43 A;  4NWF A;  1M27 A;  2AUG A;  4JE4 A;  1WQU A;  5KAZ A;  4FBN A;  2EKX A;  2DVJ A;  1X27 A;  3VS5 A;  2KNO A;  1LUM A;  2FCI A;  1NRV A;  2OQ1 A;  2LQW A;  1M61 A;  1JWO A;  3QWY A;  4GWF A;  4DGP A;  5EG3 B;  4JEG A;  1TCE A;  1A1C A;  1SHA A;  2GE9 A;  3VRY A;  1HCT B;  4LUE A;  2XP1 A;  1OPK A;  1CSY A;  1BHH B;  2PLE A;  3MXC A;  3US4 A;  3VS1 A;  1F1W A;  2H8H A;  3ZNI A;  1AOT F;  2IUH A;  4K44 A;  4ROJ A;  1R1S A;  1D4W A;  4K45 A;  2AOA A;  3VRN A;  1A09 A;  5DC4 A;  1O45 A;  1KC2 A;  3BUM B;  1O4H A;  2ETZ A;  2MK2 A;  2MRK A;  1R1Q A;  1AYB A;  3PS5 A;  1LKK A;  1O4G A;  2PNB A;  3WA4 A;  3VS6 A;  3PFV A;  4NWG A;  3KFJ A;  1LKL A;  1QAD A;  3VS2 A;  5AXI A;  1JU5 A;  2CI8 A;  3BKB A;  1O4C A;  2Y1M A;  1AB2 A;  1B47 A;  3BUN B;  2HMH A;  1AYD A;  3HIZ B;  3S9K A;  2MC1 A;  1FBV A;  3VRZ A;  2DX0 A;  3S8L A;  3IN7 A;  2LCT A;  3EAC A;  1FMK A;  3VS3 A;  2PLD A;  5EHR A;  1MW4 A;  1IJR A;  1UUS A;  5I6V A;  2L4K A;  3VS7 A;  1A1B A;  5IBM A;  1K9A A;  3T04 A;  1TZE E;  2PNA A;  2SHP A;  2B3O A;  4WWQ A;  3C7I A;  4JGH A;  4DGX A;  5DC0 B;  2Y3A B;  3UYO A;  5IBS A;  2EOB A;  1FYR A;  3HHM B;  3PQZ A;  2CRH A;  3CWG A;  1LUK A;  2RSY A;  3PLF B;  3VRQ A;  2EL8 A;  4OHI A;  3PSJ A;  3IMD A;  4U17 A;  1A1E A;  2HUW A;  1IS0 A;  2IUG A;  1QCF A;  1RQQ C;  4QSY A;  5EEL A;  5HKZ A;  1YVH A;  3OV1 A;  1BLJ A;  2RVF A;  3IMJ A;  3K2T A;  1BHF A;  1I3Z A;  1LCK A;  5HKY A;  1O41 A;  2OZO A;  1LUN A;  4E68 A;  1BM2 A;  4LUD A;  1P13 A;  1ZFP E;  2CBL A;  5EEQ A;  3OVE A;  1O4Q A;  2LNX A;  1O4A A;  2SRC A;  2EO6 A;  5J3X A;  2EYZ A;  3PJP A;  2C0O A;  1Y57 A;  2DLZ A;  3BUX B;  1O4M A;  1R1P A;  1O4O A;  1SPR A;  3N84 A;  1O4N A;  4K11 A;  1X6C A;  3VS0 A;  3OB1 B;  1O48 A;  3GQI B;  2FO0 A;  2YU7 A;  3CXL A;  2K79 B;  4GPL B;  5AUL A;  1CSZ A;  3N7Y A;  1BG1 A;  1A81 A;  2CS0 A;  1NZV A;  2HDV A;  1O4E A;  3TL0 A;  2DLY A;  2KK6 A;  3BUO B;  4XZ1 A;  2ECD A;  2CR4 A;  2YSX A;  4GL9 E;  2JYQ A;  1O4D A;  1BLK A;  1FBZ A;  4K2R A;  1O4K A;  1OO4 A;  3VRO A;  1BFI A;  2IUI A;  2KGY A;  5DC9 A;  2GSB A;  2L3T A;  1SHB A;  3EAZ A;  4D8K A;  1HCS B;  1D1Z A;  3GXW A;  1BMB A;  1O46 A;  3CBL A;  2BBU A;  1O47 A;  3GXX A;  1RJA A;  1JYQ A;  1O4P A;  4EIH A;  2C0I A;  4OHD A;  1O4I A;  1A07 A;  2LQN A;  2MRJ A;  1LUI A;  1BKM A;  2H5K A;  1AOU F;  3VRR A;  5D0J A;  2CI9 A;  4OHE A; 
#chains in the Genus database with same CATH homology
 3S8N A;  3UF4 A;  1KA6 A;  1O4L A;  2VIF A;  4H34 A;  2C0T A;  2K7A B;  1O4F A;  1LCJ A;  2LNW A;  2HDX A;  1BKL A;  2ROR A;  3CD3 A;  1JYR A;  1BF5 A;  2AOB A;  3HCK A;  3OP0 A;  3IN8 A;  3VRP A;  1Y1U A;  4P9V A;  3S8O A;  2IZV A;  3VGO A;  1O4B A;  1NZL A;  2RMX A;  1G83 A;  1SHD A;  4M4Z A;  2C9W A;  1A08 A;  2DCR A;  4H1O A;  3QWX X;  3OB2 B;  3PSK A;  1CWE A;  1OPL A;  1PIC A;  1QG1 E;  1D4T A;  1JYU A;  1AYA A;  2EU0 A;  5DF6 A;  3K2M A;  1YVL A;  4F59 A;  3MAZ A;  4F5B A;  1UUR A;  3MXY A;  4XZ0 A;  1AYC A;  4EY0 A;  4A4B A;  2HCK A;  4FL3 A;  1KA7 A;  4U1P A;  1GRI A;  4FL2 A;  4OHH A;  1OO3 A;  5HKW A;  1X0N A;  2L6K A;  1O4R A;  3NHN A;  4F5A A;  1A1A A;  1GHU A;  1SKJ A;  2Y1N A;  2MQI A;  1O4J A;  3BUW B;  4L1B B;  1H9O A;  1FU5 A;  1Z3K A;  1FU6 A;  1MIL A;  1O44 A;  2CIA A;  1CWD L;  2DM0 A;  2ABL A;  2QMS A;  1FHS A;  2EYY A;  1AD5 A;  5BO4 A;  1O49 A;  1KSW A;  2EYV A;  3M7F A;  4OHL A;  5EHP A;  2PTK A;  1CJ1 A;  1O42 A;  1RPY A;  1F2F A;  4E93 A;  4A4C A;  3TKZ A;  1XA6 A;  4X6S A;  3N8M A;  5GJH A;  3VS4 A;  1SPS A;  5GJI A;  1BFJ A;  4TZI A;  1BHH A;  2EO3 A;  4P9Z A;  2H46 E;  5CDW A;  1O43 A;  4NWF A;  1M27 A;  2AUG A;  4JE4 A;  1WQU A;  5KAZ A;  4FBN A;  2EKX A;  2DVJ A;  1X27 A;  3VS5 A;  2KNO A;  1LUM A;  2FCI A;  1NRV A;  2OQ1 A;  2LQW A;  1M61 A;  1JWO A;  3QWY A;  4GWF A;  4DGP A;  5EG3 B;  4JEG A;  1TCE A;  1A1C A;  1SHA A;  2GE9 A;  3VRY A;  1HCT B;  4LUE A;  2XP1 A;  1OPK A;  1CSY A;  1BHH B;  2PLE A;  3MXC A;  3US4 A;  3VS1 A;  1F1W A;  2H8H A;  3ZNI A;  1AOT F;  2IUH A;  4K44 A;  4ROJ A;  1R1S A;  1D4W A;  4K45 A;  2AOA A;  3VRN A;  1A09 A;  5DC4 A;  1O45 A;  1KC2 A;  3BUM B;  1O4H A;  2ETZ A;  2MK2 A;  2MRK A;  1R1Q A;  1AYB A;  3PS5 A;  1LKK A;  1O4G A;  2PNB A;  3WA4 A;  3VS6 A;  3PFV A;  4NWG A;  3KFJ A;  1LKL A;  1QAD A;  3VS2 A;  5AXI A;  1JU5 A;  2CI8 A;  3BKB A;  1O4C A;  2Y1M A;  1AB2 A;  1B47 A;  3BUN B;  2HMH A;  1AYD A;  3HIZ B;  3S9K A;  2MC1 A;  1FBV A;  3VRZ A;  2DX0 A;  3S8L A;  3IN7 A;  2LCT A;  3EAC A;  1FMK A;  3VS3 A;  2PLD A;  5EHR A;  1MW4 A;  1IJR A;  1UUS A;  5I6V A;  2L4K A;  3VS7 A;  1A1B A;  5IBM A;  1K9A A;  3T04 A;  1TZE E;  2PNA A;  2SHP A;  2B3O A;  4WWQ A;  3C7I A;  4JGH A;  4DGX A;  5DC0 B;  2Y3A B;  3UYO A;  5IBS A;  2EOB A;  1FYR A;  3HHM B;  3PQZ A;  2CRH A;  3CWG A;  1LUK A;  2RSY A;  3PLF B;  3VRQ A;  2EL8 A;  4OHI A;  3PSJ A;  3IMD A;  4U17 A;  1A1E A;  2HUW A;  1IS0 A;  2IUG A;  1QCF A;  1RQQ C;  4QSY A;  5EEL A;  5HKZ A;  1YVH A;  3OV1 A;  1BLJ A;  2RVF A;  3IMJ A;  1BHF A;  1I3Z A;  1LCK A;  5HKY A;  1O41 A;  2OZO A;  1LUN A;  4E68 A;  1BM2 A;  4LUD A;  1P13 A;  1ZFP E;  2CBL A;  5EEQ A;  3OVE A;  1O4Q A;  2LNX A;  1O4A A;  2SRC A;  2EO6 A;  5J3X A;  2EYZ A;  3PJP A;  2C0O A;  1Y57 A;  2DLZ A;  3BUX B;  1O4M A;  1R1P A;  1O4O A;  1SPR A;  3N84 A;  1O4N A;  4K11 A;  1X6C A;  3VS0 A;  3OB1 B;  1O48 A;  3GQI B;  2FO0 A;  2YU7 A;  3CXL A;  2K79 B;  4GPL B;  5AUL A;  1CSZ A;  3N7Y A;  1BG1 A;  1A81 A;  2CS0 A;  1NZV A;  2HDV A;  1O4E A;  3TL0 A;  2DLY A;  2KK6 A;  3BUO B;  4XZ1 A;  2ECD A;  2CR4 A;  2YSX A;  4GL9 E;  2JYQ A;  1O4D A;  1BLK A;  1FBZ A;  4K2R A;  1O4K A;  1OO4 A;  3VRO A;  1BFI A;  2IUI A;  5DC9 A;  2GSB A;  2L3T A;  1SHB A;  3EAZ A;  4D8K A;  1HCS B;  1D1Z A;  3GXW A;  1BMB A;  1O46 A;  3CBL A;  2BBU A;  1O47 A;  3GXX A;  1RJA A;  1JYQ A;  1O4P A;  4EIH A;  2C0I A;  4OHD A;  1O4I A;  1A07 A;  2LQN A;  2MRJ A;  1LUI A;  1BKM A;  2H5K A;  1AOU F;  3VRR A;  5D0J A;  2CI9 A;  4OHE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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