1LUKA

Nmr structure of the itk sh2 domain, pro287cis, energy minimized average structure
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
108
structure length
108
Chain Sequence
NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a proline-driven conformational switch within the Itk SH2 domain
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Tyrosine-protein kinase ITK/TSK
total genus 13
structure length 108
sequence length 108
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2002-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1lukA00
4FL3A 1ZFPE 1YVHA 2LQWA 2RMXA 2QMSA 3PLFB 1BFJA 5AXIA 1BM2A 4OHHA 1SPSA 5EHPA 1CSZA 1OPLA 1A1AA 3EACA 4LUDA 1LUKA 2AUGA 1BF5A 1KC2A 2SHPA 3VRRA 3K2MA 1X0NA 3GXWA 2GSBA 4OHIA 4XZ1A 2B3OA 3PSJA 2HDXA 4F5AA 4H34A 4K44A 3MXYA 3GXXA 4TZIA 2VIFA 2XP1A 2DCRA 1LKLA 5GJIA 2KNOA 2MK2A 2L3TA 4A4CA 1FHSA 4JEGA 1A1CA 4QSYA 3VS2A 1AYAA 1Y1UA 3VS0A 3VRYA 1AB2A 1O4QA 3VS1A 3S8OA 2HUWA 2RORA 3S8LA 1XA6A 3VS3A 4U17A 1O4NA 1M61A 1KA7A 5BO4A 1BLKA 4FBNA 5KAZA 2C0TA 1KSWA 5I6VA 2PNBA 4WWQA 2H8HA 3NHNA 1BLJA 3US4A 1A1BA 4NWFA 1UUSA 1SPRA 1H9OA 1I3ZA 1SHBA 3N8MA 2EO6A 2HDVA 3VRQA 3S8NA 3VS7A 1HCTB 1QG1E 3HCKA 1AYDA 4P9ZA 3BUOB 3IN8A 1FBVA 1QCFA 5CDWA 3PSKA 2K7AB 5EELA 2LNWA 3CBLA 1LUMA 3IMJA 3OB1B 3IMDA 1O4DA 1O46A 5J3XA 1FU6A 2EOBA 1O4GA 4LUEA 1BHHB 1O4EA 2CI9A 2LNXA 3VS5A 3TL0A 4P9VA 2MRKA 3PJPA 1D1ZA 2FCIA 1O44A 1R1SA 1O42A 2L6KA 2H46E 1BHFA 3IN7A 1HCSB 2IUIA 4A4BA 4K11A 3VROA 2C0OA 2YSXA 2KK6A 1O4LA 1FMKA 3WA4A 2H5KA 1LCKA 4M4ZA 1O41A 2AOAA 1O4KA 2PTKA 4K45A 1NZVA 4U1PA 1AYBA 1A08A 1FYRA 5GJHA 4K2RA 1LKKA 1P13A 2CS0A 4GWFA 1KA6A 2DX0A 2L4KA 3N84A 2IZVA 5HKZA 4H1OA 2C0IA 1GHUA 2CBLA 1X6CA 5D0JA 1BG1A 1FBZA 1O4IA 3BUWB 5EEQA 1O49A 5EG3B 1O4OA 3CXLA 1FU5A 4OHEA 3M7FA 3TKZA 1AOUF 1YVLA 3EAZA 3OB2B 1CSYA 1BFIA 3BUMB 1D4TA 2EU0A 1A81A 1O4AA 2Y3AB 1B47A 4FL2A 1Z3KA 2IUHA 3OV1A 2DM0A 2MRJA 3PQZA 3BUNB 1AOTF 2DVJA 2RSYA 1LCJA 1O4MA 1O47A 3VS6A 3S9KA 2Y1MA 4EIHA 2EO3A 3ZNIA 1O48A 1SHDA 5IBSA 1O45A 3QWXX 2EKXA 2C9WA 4X6SA 1M27A 1PICA 3VRPA 5DF6A 2GE9A 2DLYA 4NWGA 1JYRA 1BMBA 2MQIA 2CI8A 3HIZB 3MAZA 4DGPA 5EHRA 2EYYA 2CRHA 1A09A 1CJ1A 3QWYA 1LUNA 2RVFA 1JWOA 1F1WA 1JU5A 1SHAA 3CD3A 4OHLA 1G83A 2DLZA 1O4PA 1O4BA 5DC9A 2PNAA 2EYVA 5HKYA 3VRZA 2Y1NA 1AD5A 1NRVA 1UURA 1CWDL 3CWGA 3VGOA 3BKBA 1JYQA 1OO4A 2ETZA 1D4WA 3C7IA 1MW4A 4L1BB 1NZLA 1GRIA 2K79B 4JE4A 4F59A 1F2FA 1RQQC 1OO3A 1K9AA 2EL8A 1A1EA 4E68A 2HCKA 3MXCA 1MILA 2EYZA 1LUIA 2CR4A 1RJAA 1AYCA 2SRCA 3HHMB 4DGXA 2OZOA 1OPKA 1CWEA 4GPLB 1TZEE 2ABLA 3GQIB 4JGHA 1O4HA 4F5BA 2PLEA 2PLDA 5AULA 1R1PA 3N7YA 3VS4A 1O4FA 4EY0A 3PFVA 1SKJA 1TCEA 3UYOA 2CIAA 4E93A 3BUXB 4OHDA 2BBUA 1O4RA 1IS0A 5HKWA 1O43A 1BHHA 1R1QA 1O4CA 2LCTA 1IJRA 3OVEA 1RPYA 1BKLA 5DC0B 2OQ1A 4GL9E 3KFJA 2ECDA 2LQNA 1QADA 1A07A 1JYUA 1O4JA 3T04A 2IUGA 4XZ0A 3PS5A 2FO0A 1BKMA 2JYQA 3VRNA 2YU7A 5DC4A 2HMHA 1WQUA 2AOBA 4ROJA 3UF4A 2MC1A 4D8KA 5IBMA 3OP0A 1Y57A 1X27A
chains in the Genus database with same CATH superfamily
4FL3A 1ZFPE 1YVHA 2LQWA 2RMXA 2QMSA 3PLFB 1BFJA 5AXIA 2KGYA 1BM2A 4OHHA 1SPSA 5EHPA 1CSZA 1OPLA 3K2TA 1A1AA 3EACA 4LUDA 1LUKA 2AUGA 1BF5A 1KC2A 2SHPA 3VRRA 3K2MA 1X0NA 3GXWA 2GSBA 4OHIA 4XZ1A 2B3OA 3PSJA 2HDXA 4F5AA 4H34A 4K44A 3LYVA 3MXYA 3GXXA 4TZIA 2VIFA 2XP1A 2DCRA 1LKLA 5GJIA 2KNOA 2MK2A 2L3TA 4A4CA 1FHSA 4JEGA 1A1CA 4QSYA 3VS2A 1AYAA 1Y1UA 3VS0A 3VRYA 1AB2A 1O4QA 3VS1A 3S8OA 2HUWA 2RORA 3S8LA 1XA6A 3VS3A 4U17A 1O4NA 1M61A 1KA7A 5BO4A 1BLKA 4FBNA 5KAZA 2C0TA 1KSWA 5I6VA 2PNBA 4WWQA 2H8HA 3NHNA 1BLJA 3US4A 1A1BA 4NWFA 1UUSA 1SPRA 1H9OA 1I3ZA 1SHBA 3N8MA 2EO6A 2HDVA 3VRQA 3S8NA 3VS7A 1HCTB 1QG1E 3HCKA 1AYDA 4P9ZA 3BUOB 3IN8A 1FBVA 1QCFA 5CDWA 3PSKA 2K7AB 5EELA 2LNWA 3CBLA 1LUMA 3IMJA 3OB1B 3IMDA 1O4DA 1O46A 5J3XA 1FU6A 2EOBA 1O4GA 4LUEA 1BHHB 1O4EA 2CI9A 2LNXA 3VS5A 3TL0A 4P9VA 2MRKA 2LRAA 3PJPA 1D1ZA 2FCIA 1O44A 1R1SA 1O42A 2L6KA 2H46E 1BHFA 3IN7A 1HCSB 2IUIA 4A4BA 4K11A 3VROA 2C0OA 2YSXA 2KK6A 1O4LA 1FMKA 3WA4A 2H5KA 1LCKA 4M4ZA 1O41A 2AOAA 1O4KA 2PTKA 4K45A 1NZVA 4U1PA 1AYBA 1A08A 1FYRA 5GJHA 4K2RA 1LKKA 1P13A 2CS0A 4GWFA 1KA6A 2DX0A 2L4KA 3N84A 2IZVA 5HKZA 4H1OA 2C0IA 1GHUA 2CBLA 1X6CA 5D0JA 1BG1A 1FBZA 1O4IA 3BUWB 5EEQA 1O49A 5EG3B 1O4OA 3CXLA 1FU5A 4OHEA 3M7FA 3TKZA 1AOUF 1YVLA 3EAZA 3OB2B 1CSYA 1BFIA 3BUMB 1D4TA 2EU0A 1A81A 1O4AA 2Y3AB 1B47A 4FL2A 1Z3KA 2IUHA 3OV1A 2DM0A 2MRJA 3PQZA 3BUNB 1AOTF 2DVJA 2RSYA 1LCJA 1O4MA 1O47A 3VS6A 3S9KA 2Y1MA 4EIHA 2EO3A 3ZNIA 1O48A 1SHDA 5IBSA 1O45A 3QWXX 2EKXA 2C9WA 4X6SA 1M27A 1PICA 3VRPA 5DF6A 2GE9A 2DLYA 4NWGA 1JYRA 1BMBA 2MQIA 2CI8A 3HIZB 3MAZA 4DGPA 5EHRA 2EYYA 2CRHA 1A09A 1CJ1A 3QWYA 1LUNA 2RVFA 1JWOA 1F1WA 1JU5A 1SHAA 3CD3A 4OHLA 1G83A 2DLZA 1O4PA 1O4BA 5DC9A 2PNAA 2EYVA 5HKYA 3VRZA 2Y1NA 1AD5A 1NRVA 1UURA 1CWDL 3CWGA 3VGOA 3BKBA 1JYQA 1OO4A 2ETZA 1D4WA 3C7IA 1MW4A 4L1BB 1NZLA 1GRIA 2K79B 4JE4A 4F59A 1F2FA 1RQQC 1OO3A 1K9AA 2EL8A 1A1EA 4E68A 2HCKA 3MXCA 1MILA 2EYZA 1LUIA 2CR4A 1RJAA 1AYCA 2SRCA 3HHMB 4DGXA 2OZOA 1OPKA 1CWEA 4GPLB 1TZEE 2ABLA 3GQIB 4JGHA 1O4HA 4F5BA 2PLEA 2PLDA 5AULA 1R1PA 3N7YA 3VS4A 1O4FA 4EY0A 3PFVA 1SKJA 1TCEA 3UYOA 2CIAA 4E93A 3BUXB 4OHDA 2BBUA 1O4RA 1IS0A 5HKWA 1O43A 1BHHA 1R1QA 1O4CA 2LCTA 1IJRA 3OVEA 1RPYA 1BKLA 5DC0B 2OQ1A 4GL9E 3KFJA 2ECDA 2LQNA 1QADA 1A07A 1JYUA 1O4JA 3T04A 2IUGA 4XZ0A 3PS5A 2FO0A 1BKMA 2JYQA 3VRNA 2YU7A 5DC4A 2HMHA 1WQUA 2AOBA 4ROJA 3UF4A 2MC1A 4D8KA 5IBMA 3OP0A 1Y57A 1X27A
chains in the Genus database with same CATH topology
4FL3A 1ZFPE 1YVHA 2LQWA 2RMXA 2QMSA 3PLFB 1BFJA 5AXIA 1BM2A 4OHHA 1SPSA 5EHPA 1CSZA 1OPLA 1A1AA 3EACA 4LUDA 1LUKA 2AUGA 1BF5A 1KC2A 2SHPA 3VRRA 3K2MA 1X0NA 3GXWA 2GSBA 4OHIA 4XZ1A 2B3OA 3PSJA 2HDXA 4F5AA 4H34A 4K44A 3MXYA 3GXXA 4TZIA 2VIFA 2XP1A 2DCRA 1LKLA 5GJIA 2KNOA 2MK2A 2L3TA 4A4CA 1FHSA 4JEGA 1A1CA 4QSYA 3VS2A 1AYAA 1Y1UA 3VS0A 3VRYA 1AB2A 1O4QA 3VS1A 3S8OA 2HUWA 2RORA 3S8LA 1XA6A 3VS3A 4U17A 1O4NA 1M61A 1KA7A 5BO4A 1BLKA 4FBNA 5KAZA 2C0TA 1KSWA 5I6VA 2PNBA 4WWQA 2H8HA 3NHNA 1BLJA 3US4A 1A1BA 4NWFA 1UUSA 1SPRA 1H9OA 1I3ZA 1SHBA 3N8MA 2EO6A 2HDVA 3VRQA 3S8NA 3VS7A 1HCTB 1QG1E 3HCKA 1AYDA 4P9ZA 3BUOB 3IN8A 1FBVA 1QCFA 5CDWA 3PSKA 2K7AB 5EELA 2LNWA 3CBLA 1LUMA 3IMJA 3OB1B 3IMDA 1O4DA 1O46A 5J3XA 1FU6A 2EOBA 1O4GA 4LUEA 1BHHB 1O4EA 2CI9A 2LNXA 3VS5A 3TL0A 4P9VA 2MRKA 3PJPA 1D1ZA 2FCIA 1O44A 1R1SA 1O42A 2L6KA 2H46E 1BHFA 3IN7A 1HCSB 2IUIA 4A4BA 4K11A 3VROA 2C0OA 2YSXA 2KK6A 1O4LA 1FMKA 3WA4A 2H5KA 1LCKA 4M4ZA 1O41A 2AOAA 1O4KA 2PTKA 4K45A 1NZVA 4U1PA 1AYBA 1A08A 1FYRA 5GJHA 4K2RA 1LKKA 1P13A 2CS0A 4GWFA 1KA6A 2DX0A 2L4KA 3N84A 2IZVA 5HKZA 4H1OA 2C0IA 1GHUA 2CBLA 1X6CA 5D0JA 1BG1A 1FBZA 1O4IA 3BUWB 5EEQA 1O49A 5EG3B 1O4OA 3CXLA 1FU5A 4OHEA 3M7FA 3TKZA 1AOUF 1YVLA 3EAZA 3OB2B 1CSYA 1BFIA 3BUMB 1D4TA 2EU0A 1A81A 1O4AA 2Y3AB 1B47A 4FL2A 1Z3KA 2IUHA 3OV1A 2DM0A 2MRJA 3PQZA 3BUNB 1AOTF 2DVJA 2RSYA 1LCJA 1O4MA 1O47A 3VS6A 3S9KA 2Y1MA 4EIHA 2EO3A 3ZNIA 1O48A 1SHDA 5IBSA 1O45A 3QWXX 2EKXA 2C9WA 4X6SA 1M27A 1PICA 3VRPA 5DF6A 2GE9A 2DLYA 4NWGA 1JYRA 1BMBA 2MQIA 2CI8A 3HIZB 3MAZA 4DGPA 5EHRA 2EYYA 2CRHA 1A09A 1CJ1A 3QWYA 1LUNA 2RVFA 1JWOA 1F1WA 1JU5A 1SHAA 3CD3A 4OHLA 1G83A 2DLZA 1O4PA 1O4BA 5DC9A 2PNAA 2EYVA 5HKYA 3VRZA 2Y1NA 1AD5A 1NRVA 1UURA 1CWDL 3CWGA 3VGOA 3BKBA 1JYQA 1OO4A 2ETZA 1D4WA 3C7IA 1MW4A 4L1BB 1NZLA 1GRIA 2K79B 4JE4A 4F59A 1F2FA 1RQQC 1OO3A 1K9AA 2EL8A 1A1EA 4E68A 2HCKA 3MXCA 1MILA 2EYZA 1LUIA 2CR4A 1RJAA 1AYCA 2SRCA 3HHMB 4DGXA 2OZOA 1OPKA 1CWEA 4GPLB 1TZEE 2ABLA 3GQIB 4JGHA 1O4HA 4F5BA 2PLEA 2PLDA 5AULA 1R1PA 3N7YA 3VS4A 1O4FA 4EY0A 3PFVA 1SKJA 1TCEA 3UYOA 2CIAA 4E93A 3BUXB 4OHDA 2BBUA 1O4RA 1IS0A 5HKWA 1O43A 1BHHA 1R1QA 1O4CA 2LCTA 1IJRA 3OVEA 1RPYA 1BKLA 5DC0B 2OQ1A 4GL9E 3KFJA 2ECDA 2LQNA 1QADA 1A07A 1JYUA 1O4JA 3T04A 2IUGA 4XZ0A 3PS5A 2FO0A 1BKMA 2JYQA 3VRNA 2YU7A 5DC4A 2HMHA 1WQUA 2AOBA 4ROJA 3UF4A 2MC1A 4D8KA 5IBMA 3OP0A 1Y57A 1X27A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FL3 A;  1ZFP E;  1YVH A;  2LQW A;  2RMX A;  2QMS A;  3PLF B;  1BFJ A;  5AXI A;  1BM2 A;  4OHH A;  1SPS A;  5EHP A;  1CSZ A;  1OPL A;  1A1A A;  3EAC A;  4LUD A;  1LUK A;  2AUG A;  1BF5 A;  1KC2 A;  2SHP A;  3VRR A;  3K2M A;  1X0N A;  3GXW A;  2GSB A;  4OHI A;  4XZ1 A;  2B3O A;  3PSJ A;  2HDX A;  4F5A A;  4H34 A;  4K44 A;  3MXY A;  3GXX A;  4TZI A;  2VIF A;  2XP1 A;  2DCR A;  1LKL A;  5GJI A;  2KNO A;  2MK2 A;  2L3T A;  4A4C A;  1FHS A;  4JEG A;  1A1C A;  4QSY A;  3VS2 A;  1AYA A;  1Y1U A;  3VS0 A;  3VRY A;  1AB2 A;  1O4Q A;  3VS1 A;  3S8O A;  2HUW A;  2ROR A;  3S8L A;  1XA6 A;  3VS3 A;  4U17 A;  1O4N A;  1M61 A;  1KA7 A;  5BO4 A;  1BLK A;  4FBN A;  5KAZ A;  2C0T A;  1KSW A;  5I6V A;  2PNB A;  4WWQ A;  2H8H A;  3NHN A;  1BLJ A;  3US4 A;  1A1B A;  4NWF A;  1UUS A;  1SPR A;  1H9O A;  1I3Z A;  1SHB A;  3N8M A;  2EO6 A;  2HDV A;  3VRQ A;  3S8N A;  3VS7 A;  1HCT B;  1QG1 E;  3HCK A;  1AYD A;  4P9Z A;  3BUO B;  3IN8 A;  1FBV A;  1QCF A;  5CDW A;  3PSK A;  2K7A B;  5EEL A;  2LNW A;  3CBL A;  1LUM A;  3IMJ A;  3OB1 B;  3IMD A;  1O4D A;  1O46 A;  5J3X A;  1FU6 A;  2EOB A;  1O4G A;  4LUE A;  1BHH B;  1O4E A;  2CI9 A;  2LNX A;  3VS5 A;  3TL0 A;  4P9V A;  2MRK A;  3PJP A;  1D1Z A;  2FCI A;  1O44 A;  1R1S A;  1O42 A;  2L6K A;  2H46 E;  1BHF A;  3IN7 A;  1HCS B;  2IUI A;  4A4B A;  4K11 A;  3VRO A;  2C0O A;  2YSX A;  2KK6 A;  1O4L A;  1FMK A;  3WA4 A;  2H5K A;  1LCK A;  4M4Z A;  1O41 A;  2AOA A;  1O4K A;  2PTK A;  4K45 A;  1NZV A;  4U1P A;  1AYB A;  1A08 A;  1FYR A;  5GJH A;  4K2R A;  1LKK A;  1P13 A;  2CS0 A;  4GWF A;  1KA6 A;  2DX0 A;  2L4K A;  3N84 A;  2IZV A;  5HKZ A;  4H1O A;  2C0I A;  1GHU A;  2CBL A;  1X6C A;  5D0J A;  1BG1 A;  1FBZ A;  1O4I A;  3BUW B;  5EEQ A;  1O49 A;  5EG3 B;  1O4O A;  3CXL A;  1FU5 A;  4OHE A;  3M7F A;  3TKZ A;  1AOU F;  1YVL A;  3EAZ A;  3OB2 B;  1CSY A;  1BFI A;  3BUM B;  1D4T A;  2EU0 A;  1A81 A;  1O4A A;  2Y3A B;  1B47 A;  4FL2 A;  1Z3K A;  2IUH A;  3OV1 A;  2DM0 A;  2MRJ A;  3PQZ A;  3BUN B;  1AOT F;  2DVJ A;  2RSY A;  1LCJ A;  1O4M A;  1O47 A;  3VS6 A;  3S9K A;  2Y1M A;  4EIH A;  2EO3 A;  3ZNI A;  1O48 A;  1SHD A;  5IBS A;  1O45 A;  3QWX X;  2EKX A;  2C9W A;  4X6S A;  1M27 A;  1PIC A;  3VRP A;  5DF6 A;  2GE9 A;  2DLY A;  4NWG A;  1JYR A;  1BMB A;  2MQI A;  2CI8 A;  3HIZ B;  3MAZ A;  4DGP A;  5EHR A;  2EYY A;  2CRH A;  1A09 A;  1CJ1 A;  3QWY A;  1LUN A;  2RVF A;  1JWO A;  1F1W A;  1JU5 A;  1SHA A;  3CD3 A;  4OHL A;  1G83 A;  2DLZ A;  1O4P A;  1O4B A;  5DC9 A;  2PNA A;  2EYV A;  5HKY A;  3VRZ A;  2Y1N A;  1AD5 A;  1NRV A;  1UUR A;  1CWD L;  3CWG A;  3VGO A;  3BKB A;  1JYQ A;  1OO4 A;  2ETZ A;  1D4W A;  3C7I A;  1MW4 A;  4L1B B;  1NZL A;  1GRI A;  2K79 B;  4JE4 A;  4F59 A;  1F2F A;  1RQQ C;  1OO3 A;  1K9A A;  2EL8 A;  1A1E A;  4E68 A;  2HCK A;  3MXC A;  1MIL A;  2EYZ A;  1LUI A;  2CR4 A;  1RJA A;  1AYC A;  2SRC A;  3HHM B;  4DGX A;  2OZO A;  1OPK A;  1CWE A;  4GPL B;  1TZE E;  2ABL A;  3GQI B;  4JGH A;  1O4H A;  4F5B A;  2PLE A;  2PLD A;  5AUL A;  1R1P A;  3N7Y A;  3VS4 A;  1O4F A;  4EY0 A;  3PFV A;  1SKJ A;  1TCE A;  3UYO A;  2CIA A;  4E93 A;  3BUX B;  4OHD A;  2BBU A;  1O4R A;  1IS0 A;  5HKW A;  1O43 A;  1BHH A;  1R1Q A;  1O4C A;  2LCT A;  1IJR A;  3OVE A;  1RPY A;  1BKL A;  5DC0 B;  2OQ1 A;  4GL9 E;  3KFJ A;  2ECD A;  2LQN A;  1QAD A;  1A07 A;  1JYU A;  1O4J A;  3T04 A;  2IUG A;  4XZ0 A;  3PS5 A;  2FO0 A;  1BKM A;  2JYQ A;  3VRN A;  2YU7 A;  5DC4 A;  2HMH A;  1WQU A;  2AOB A;  4ROJ A;  3UF4 A;  2MC1 A;  4D8K A;  5IBM A;  3OP0 A;  1Y57 A;  1X27 A; 
#chains in the Genus database with same CATH topology
 4FL3 A;  1ZFP E;  1YVH A;  2LQW A;  2RMX A;  2QMS A;  3PLF B;  1BFJ A;  5AXI A;  2KGY A;  1BM2 A;  4OHH A;  1SPS A;  5EHP A;  1CSZ A;  1OPL A;  3K2T A;  1A1A A;  3EAC A;  4LUD A;  1LUK A;  2AUG A;  1BF5 A;  1KC2 A;  2SHP A;  3VRR A;  3K2M A;  1X0N A;  3GXW A;  2GSB A;  4OHI A;  4XZ1 A;  2B3O A;  3PSJ A;  2HDX A;  4F5A A;  4H34 A;  4K44 A;  3LYV A;  3MXY A;  3GXX A;  4TZI A;  2VIF A;  2XP1 A;  2DCR A;  1LKL A;  5GJI A;  2KNO A;  2MK2 A;  2L3T A;  4A4C A;  1FHS A;  4JEG A;  1A1C A;  4QSY A;  3VS2 A;  1AYA A;  1Y1U A;  3VS0 A;  3VRY A;  1AB2 A;  1O4Q A;  3VS1 A;  3S8O A;  2HUW A;  2ROR A;  3S8L A;  1XA6 A;  3VS3 A;  4U17 A;  1O4N A;  1M61 A;  1KA7 A;  5BO4 A;  1BLK A;  4FBN A;  5KAZ A;  2C0T A;  1KSW A;  5I6V A;  2PNB A;  4WWQ A;  2H8H A;  3NHN A;  1BLJ A;  3US4 A;  1A1B A;  4NWF A;  1UUS A;  1SPR A;  1H9O A;  1I3Z A;  1SHB A;  3N8M A;  2EO6 A;  2HDV A;  3VRQ A;  3S8N A;  3VS7 A;  1HCT B;  1QG1 E;  3HCK A;  1AYD A;  4P9Z A;  3BUO B;  3IN8 A;  1FBV A;  1QCF A;  5CDW A;  3PSK A;  2K7A B;  5EEL A;  2LNW A;  3CBL A;  1LUM A;  3IMJ A;  3OB1 B;  3IMD A;  1O4D A;  1O46 A;  5J3X A;  1FU6 A;  2EOB A;  1O4G A;  4LUE A;  1BHH B;  1O4E A;  2CI9 A;  2LNX A;  3VS5 A;  3TL0 A;  4P9V A;  2MRK A;  2LRA A;  3PJP A;  1D1Z A;  2FCI A;  1O44 A;  1R1S A;  1O42 A;  2L6K A;  2H46 E;  1BHF A;  3IN7 A;  1HCS B;  2IUI A;  4A4B A;  4K11 A;  3VRO A;  2C0O A;  2YSX A;  2KK6 A;  1O4L A;  1FMK A;  3WA4 A;  2H5K A;  1LCK A;  4M4Z A;  1O41 A;  2AOA A;  1O4K A;  2PTK A;  4K45 A;  1NZV A;  4U1P A;  1AYB A;  1A08 A;  1FYR A;  5GJH A;  4K2R A;  1LKK A;  1P13 A;  2CS0 A;  4GWF A;  1KA6 A;  2DX0 A;  2L4K A;  3N84 A;  2IZV A;  5HKZ A;  4H1O A;  2C0I A;  1GHU A;  2CBL A;  1X6C A;  5D0J A;  1BG1 A;  1FBZ A;  1O4I A;  3BUW B;  5EEQ A;  1O49 A;  5EG3 B;  1O4O A;  3CXL A;  1FU5 A;  4OHE A;  3M7F A;  3TKZ A;  1AOU F;  1YVL A;  3EAZ A;  3OB2 B;  1CSY A;  1BFI A;  3BUM B;  1D4T A;  2EU0 A;  1A81 A;  1O4A A;  2Y3A B;  1B47 A;  4FL2 A;  1Z3K A;  2IUH A;  3OV1 A;  2DM0 A;  2MRJ A;  3PQZ A;  3BUN B;  1AOT F;  2DVJ A;  2RSY A;  1LCJ A;  1O4M A;  1O47 A;  3VS6 A;  3S9K A;  2Y1M A;  4EIH A;  2EO3 A;  3ZNI A;  1O48 A;  1SHD A;  5IBS A;  1O45 A;  3QWX X;  2EKX A;  2C9W A;  4X6S A;  1M27 A;  1PIC A;  3VRP A;  5DF6 A;  2GE9 A;  2DLY A;  4NWG A;  1JYR A;  1BMB A;  2MQI A;  2CI8 A;  3HIZ B;  3MAZ A;  4DGP A;  5EHR A;  2EYY A;  2CRH A;  1A09 A;  1CJ1 A;  3QWY A;  1LUN A;  2RVF A;  1JWO A;  1F1W A;  1JU5 A;  1SHA A;  3CD3 A;  4OHL A;  1G83 A;  2DLZ A;  1O4P A;  1O4B A;  5DC9 A;  2PNA A;  2EYV A;  5HKY A;  3VRZ A;  2Y1N A;  1AD5 A;  1NRV A;  1UUR A;  1CWD L;  3CWG A;  3VGO A;  3BKB A;  1JYQ A;  1OO4 A;  2ETZ A;  1D4W A;  3C7I A;  1MW4 A;  4L1B B;  1NZL A;  1GRI A;  2K79 B;  4JE4 A;  4F59 A;  1F2F A;  1RQQ C;  1OO3 A;  1K9A A;  2EL8 A;  1A1E A;  4E68 A;  2HCK A;  3MXC A;  1MIL A;  2EYZ A;  1LUI A;  2CR4 A;  1RJA A;  1AYC A;  2SRC A;  3HHM B;  4DGX A;  2OZO A;  1OPK A;  1CWE A;  4GPL B;  1TZE E;  2ABL A;  3GQI B;  4JGH A;  1O4H A;  4F5B A;  2PLE A;  2PLD A;  5AUL A;  1R1P A;  3N7Y A;  3VS4 A;  1O4F A;  4EY0 A;  3PFV A;  1SKJ A;  1TCE A;  3UYO A;  2CIA A;  4E93 A;  3BUX B;  4OHD A;  2BBU A;  1O4R A;  1IS0 A;  5HKW A;  1O43 A;  1BHH A;  1R1Q A;  1O4C A;  2LCT A;  1IJR A;  3OVE A;  1RPY A;  1BKL A;  5DC0 B;  2OQ1 A;  4GL9 E;  3KFJ A;  2ECD A;  2LQN A;  1QAD A;  1A07 A;  1JYU A;  1O4J A;  3T04 A;  2IUG A;  4XZ0 A;  3PS5 A;  2FO0 A;  1BKM A;  2JYQ A;  3VRN A;  2YU7 A;  5DC4 A;  2HMH A;  1WQU A;  2AOB A;  4ROJ A;  3UF4 A;  2MC1 A;  4D8K A;  5IBM A;  3OP0 A;  1Y57 A;  1X27 A; 
#chains in the Genus database with same CATH homology
 4FL3 A;  1ZFP E;  1YVH A;  2LQW A;  2RMX A;  2QMS A;  3PLF B;  1BFJ A;  5AXI A;  1BM2 A;  4OHH A;  1SPS A;  5EHP A;  1CSZ A;  1OPL A;  1A1A A;  3EAC A;  4LUD A;  1LUK A;  2AUG A;  1BF5 A;  1KC2 A;  2SHP A;  3VRR A;  3K2M A;  1X0N A;  3GXW A;  2GSB A;  4OHI A;  4XZ1 A;  2B3O A;  3PSJ A;  2HDX A;  4F5A A;  4H34 A;  4K44 A;  3MXY A;  3GXX A;  4TZI A;  2VIF A;  2XP1 A;  2DCR A;  1LKL A;  5GJI A;  2KNO A;  2MK2 A;  2L3T A;  4A4C A;  1FHS A;  4JEG A;  1A1C A;  4QSY A;  3VS2 A;  1AYA A;  1Y1U A;  3VS0 A;  3VRY A;  1AB2 A;  1O4Q A;  3VS1 A;  3S8O A;  2HUW A;  2ROR A;  3S8L A;  1XA6 A;  3VS3 A;  4U17 A;  1O4N A;  1M61 A;  1KA7 A;  5BO4 A;  1BLK A;  4FBN A;  5KAZ A;  2C0T A;  1KSW A;  5I6V A;  2PNB A;  4WWQ A;  2H8H A;  3NHN A;  1BLJ A;  3US4 A;  1A1B A;  4NWF A;  1UUS A;  1SPR A;  1H9O A;  1I3Z A;  1SHB A;  3N8M A;  2EO6 A;  2HDV A;  3VRQ A;  3S8N A;  3VS7 A;  1HCT B;  1QG1 E;  3HCK A;  1AYD A;  4P9Z A;  3BUO B;  3IN8 A;  1FBV A;  1QCF A;  5CDW A;  3PSK A;  2K7A B;  5EEL A;  2LNW A;  3CBL A;  1LUM A;  3IMJ A;  3OB1 B;  3IMD A;  1O4D A;  1O46 A;  5J3X A;  1FU6 A;  2EOB A;  1O4G A;  4LUE A;  1BHH B;  1O4E A;  2CI9 A;  2LNX A;  3VS5 A;  3TL0 A;  4P9V A;  2MRK A;  3PJP A;  1D1Z A;  2FCI A;  1O44 A;  1R1S A;  1O42 A;  2L6K A;  2H46 E;  1BHF A;  3IN7 A;  1HCS B;  2IUI A;  4A4B A;  4K11 A;  3VRO A;  2C0O A;  2YSX A;  2KK6 A;  1O4L A;  1FMK A;  3WA4 A;  2H5K A;  1LCK A;  4M4Z A;  1O41 A;  2AOA A;  1O4K A;  2PTK A;  4K45 A;  1NZV A;  4U1P A;  1AYB A;  1A08 A;  1FYR A;  5GJH A;  4K2R A;  1LKK A;  1P13 A;  2CS0 A;  4GWF A;  1KA6 A;  2DX0 A;  2L4K A;  3N84 A;  2IZV A;  5HKZ A;  4H1O A;  2C0I A;  1GHU A;  2CBL A;  1X6C A;  5D0J A;  1BG1 A;  1FBZ A;  1O4I A;  3BUW B;  5EEQ A;  1O49 A;  5EG3 B;  1O4O A;  3CXL A;  1FU5 A;  4OHE A;  3M7F A;  3TKZ A;  1AOU F;  1YVL A;  3EAZ A;  3OB2 B;  1CSY A;  1BFI A;  3BUM B;  1D4T A;  2EU0 A;  1A81 A;  1O4A A;  2Y3A B;  1B47 A;  4FL2 A;  1Z3K A;  2IUH A;  3OV1 A;  2DM0 A;  2MRJ A;  3PQZ A;  3BUN B;  1AOT F;  2DVJ A;  2RSY A;  1LCJ A;  1O4M A;  1O47 A;  3VS6 A;  3S9K A;  2Y1M A;  4EIH A;  2EO3 A;  3ZNI A;  1O48 A;  1SHD A;  5IBS A;  1O45 A;  3QWX X;  2EKX A;  2C9W A;  4X6S A;  1M27 A;  1PIC A;  3VRP A;  5DF6 A;  2GE9 A;  2DLY A;  4NWG A;  1JYR A;  1BMB A;  2MQI A;  2CI8 A;  3HIZ B;  3MAZ A;  4DGP A;  5EHR A;  2EYY A;  2CRH A;  1A09 A;  1CJ1 A;  3QWY A;  1LUN A;  2RVF A;  1JWO A;  1F1W A;  1JU5 A;  1SHA A;  3CD3 A;  4OHL A;  1G83 A;  2DLZ A;  1O4P A;  1O4B A;  5DC9 A;  2PNA A;  2EYV A;  5HKY A;  3VRZ A;  2Y1N A;  1AD5 A;  1NRV A;  1UUR A;  1CWD L;  3CWG A;  3VGO A;  3BKB A;  1JYQ A;  1OO4 A;  2ETZ A;  1D4W A;  3C7I A;  1MW4 A;  4L1B B;  1NZL A;  1GRI A;  2K79 B;  4JE4 A;  4F59 A;  1F2F A;  1RQQ C;  1OO3 A;  1K9A A;  2EL8 A;  1A1E A;  4E68 A;  2HCK A;  3MXC A;  1MIL A;  2EYZ A;  1LUI A;  2CR4 A;  1RJA A;  1AYC A;  2SRC A;  3HHM B;  4DGX A;  2OZO A;  1OPK A;  1CWE A;  4GPL B;  1TZE E;  2ABL A;  3GQI B;  4JGH A;  1O4H A;  4F5B A;  2PLE A;  2PLD A;  5AUL A;  1R1P A;  3N7Y A;  3VS4 A;  1O4F A;  4EY0 A;  3PFV A;  1SKJ A;  1TCE A;  3UYO A;  2CIA A;  4E93 A;  3BUX B;  4OHD A;  2BBU A;  1O4R A;  1IS0 A;  5HKW A;  1O43 A;  1BHH A;  1R1Q A;  1O4C A;  2LCT A;  1IJR A;  3OVE A;  1RPY A;  1BKL A;  5DC0 B;  2OQ1 A;  4GL9 E;  3KFJ A;  2ECD A;  2LQN A;  1QAD A;  1A07 A;  1JYU A;  1O4J A;  3T04 A;  2IUG A;  4XZ0 A;  3PS5 A;  2FO0 A;  1BKM A;  2JYQ A;  3VRN A;  2YU7 A;  5DC4 A;  2HMH A;  1WQU A;  2AOB A;  4ROJ A;  3UF4 A;  2MC1 A;  4D8K A;  5IBM A;  3OP0 A;  1Y57 A;  1X27 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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