1O41A

Crystal structure of sh2 in complex with ru78300.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o41A00
1O45A 2Y3AB 1K9AA 4K11A 4P9VA 2Y1MA 1Y1UA 4FL3A 1LCKA 3C7IA 4OHHA 4WWQA 1O4MA 3N8MA 1NRVA 4U17A 4A4CA 2GE9A 2PNBA 1O41A 3MXYA 3BUOB 2K79B 4JEGA 3PFVA 2LNWA 5DF6A 3CXLA 3TKZA 1O46A 2LCTA 3HHMB 4L1BB 3PQZA 3OVEA 2DLYA 2PNAA 1AYCA 1R1QA 4JGHA 3S9KA 1MW4A 3VS5A 1O4QA 2ECDA 3VS4A 2HDXA 3ZNIA 4TZIA 2EYVA 2EO3A 3VS7A 1A1EA 3IMJA 3HIZB 2IZVA 1D1ZA 1O44A 4OHDA 2CIAA 1M61A 3MAZA 3QWXX 2KK6A 3S8OA 1TCEA 1BMBA 4E68A 5EEQA 5EHRA 2CBLA 1LKLA 1AOTF 2DCRA 1JYUA 3NHNA 3IN7A 1O4EA 1JU5A 3GQIB 2RORA 4GWFA 3VROA 2EL8A 4FBNA 1FU6A 1X6CA 2CI8A 1IS0A 4F5BA 1BHFA 4ROJA 1TZEE 1F2FA 1Z3KA 5D0JA 1YVLA 1RJAA 5IBSA 1QG1E 1O42A 1O4JA 3EACA 1BFJA 1KA7A 2AOBA 2ABLA 1A08A 2AUGA 1BM2A 3HCKA 1HCSB 2JYQA 1FYRA 1A81A 3VS1A 1G83A 3PSKA 1SHAA 5J3XA 1BHHA 3OP0A 3T04A 3EAZA 4LUEA 1NZVA 3CBLA 4OHLA 3VS3A 1A1CA 1SPSA 2LNXA 1H9OA 1QADA 3N7YA 1SHDA 2IUGA 1BKMA 4NWFA 5DC9A 3CD3A 2H5KA 1O4IA 2EU0A 2K7AB 1RQQC 4P9ZA 3IMDA 2DM0A 2RMXA 2CR4A 1RPYA 1LUKA 3K2MA 3TL0A 1FHSA 2HDVA 4OHEA 3M7FA 1O47A 1XA6A 5BO4A 5EG3B 3UF4A 3VRQA 1FBVA 1QCFA 1BFIA 5GJIA 2KNOA 2CS0A 2HMHA 1GHUA 1LUNA 2DVJA 1O4FA 1X0NA 2H8HA 1O4AA 1BG1A 1OPLA 1O43A 2C9WA 5HKYA 1HCTB 4D8KA 2LQNA 1AD5A 1X27A 1O4DA 3MXCA 2HUWA 1O4NA 2RSYA 4F59A 2C0IA 1BLJA 2IUHA 3BUNB 3VRPA 2IUIA 2OZOA 1YVHA 2GSBA 1AOUF 4EIHA 1AYBA 2QMSA 3PSJA 4LUDA 5GJHA 1A07A 1UURA 1OO4A 3IN8A 1CWDL 4H1OA 3N84A 4E93A 1NZLA 3US4A 4FL2A 2CI9A 2B3OA 4F5AA 1O4BA 5DC0B 2EOBA 4GPLB 1R1PA 2DX0A 5EELA 2MK2A 3S8NA 4U1PA 3OB1B 3QWYA 1JWOA 2XP1A 1CJ1A 1O4HA 2Y1NA 2RVFA 1A1AA 1FMKA 4DGPA 1FBZA 2ETZA 2FCIA 1D4WA 1M27A 3WA4A 1A09A 1FU5A 5AXIA 1OPKA 1LCJA 1AYDA 4X6SA 3VRZA 3VS2A 4EY0A 1SHBA 4JE4A 4M4ZA 1SKJA 2VIFA 2L4KA 1B47A 4QSYA 3VS0A 2MC1A 1F1WA 2L3TA 4K45A 1P13A 5CDWA 3PLFB 1GRIA 3VRYA 1MILA 2MRJA 2CRHA 2HCKA 2BBUA 4NWGA 1SPRA 1O4RA 3BUXB 1CSYA 5IBMA 3OV1A 1O4KA 2AOAA 5AULA 1CSZA 3BUMB 1CWEA 1KA6A 1AYAA 1OO3A 1AB2A 2C0OA 1JYRA 1O4OA 4A4BA 1O4GA 1O4LA 2EKXA 2SHPA 4OHIA 1KSWA 3VRNA 1WQUA 2DLZA 4XZ0A 3OB2B 3BUWB 2EO6A 2PLDA 3VGOA 2FO0A 2L6KA 4GL9E 1KC2A 2YU7A 5HKZA 1JYQA 1O48A 3KFJA 2C0TA 2LQWA 5I6VA 2EYZA 1BF5A 2SRCA 1O4CA 4DGXA 1O4PA 5KAZA 3CWGA 1Y57A 3VS6A 2MRKA 2OQ1A 1A1BA 5HKWA 2PLEA 1LUMA 3VRRA 1R1SA 1LUIA 3S8LA 1O49A 1ZFPE 1LKKA 3BKBA 3GXWA 1BHHB 1IJRA 1I3ZA 2H46E 1BKLA 5DC4A 2EYYA 4K44A 2YSXA 5EHPA 3UYOA 3GXXA 1D4TA 1PICA 4XZ1A 3PJPA 1BLKA 3PS5A 1UUSA 4K2RA 2PTKA 4H34A 2MQIA
chains in the Genus database with same CATH superfamily
1O45A 2Y3AB 1K9AA 4K11A 4P9VA 2Y1MA 1Y1UA 4FL3A 1LCKA 3C7IA 4OHHA 4WWQA 1O4MA 3N8MA 1NRVA 4U17A 4A4CA 2GE9A 2PNBA 1O41A 3MXYA 3BUOB 2K79B 4JEGA 3PFVA 2LNWA 5DF6A 3CXLA 3TKZA 1O46A 2LCTA 3HHMB 4L1BB 3PQZA 3OVEA 2DLYA 2PNAA 1AYCA 1R1QA 4JGHA 3S9KA 1MW4A 3VS5A 1O4QA 2ECDA 3VS4A 2HDXA 3ZNIA 4TZIA 2EYVA 2EO3A 3VS7A 1A1EA 3IMJA 3HIZB 2IZVA 1D1ZA 1O44A 4OHDA 2CIAA 1M61A 3MAZA 3QWXX 2KK6A 3S8OA 1TCEA 1BMBA 4E68A 5EEQA 5EHRA 2CBLA 1LKLA 1AOTF 2DCRA 1JYUA 3NHNA 3IN7A 1O4EA 1JU5A 3GQIB 2RORA 4GWFA 3VROA 2EL8A 4FBNA 1FU6A 1X6CA 2CI8A 1IS0A 4F5BA 1BHFA 4ROJA 1TZEE 1F2FA 1Z3KA 5D0JA 1YVLA 1RJAA 5IBSA 1QG1E 1O42A 1O4JA 3EACA 1BFJA 1KA7A 2AOBA 2ABLA 1A08A 2AUGA 1BM2A 3HCKA 1HCSB 2JYQA 1FYRA 1A81A 3VS1A 1G83A 3PSKA 1SHAA 5J3XA 1BHHA 3OP0A 3T04A 3EAZA 4LUEA 1NZVA 3CBLA 4OHLA 3VS3A 1A1CA 1SPSA 2LNXA 1H9OA 1QADA 3N7YA 1SHDA 2IUGA 1BKMA 4NWFA 5DC9A 3CD3A 2H5KA 1O4IA 2EU0A 2K7AB 1RQQC 4P9ZA 3IMDA 2DM0A 2RMXA 2CR4A 1RPYA 1LUKA 3K2MA 3TL0A 1FHSA 2HDVA 4OHEA 3M7FA 1O47A 1XA6A 5BO4A 5EG3B 3UF4A 3VRQA 1FBVA 1QCFA 3K2TA 1BFIA 5GJIA 2KNOA 2CS0A 2HMHA 1GHUA 1LUNA 2DVJA 1O4FA 1X0NA 2H8HA 1O4AA 1BG1A 1OPLA 1O43A 2C9WA 5HKYA 1HCTB 4D8KA 2LQNA 1AD5A 1X27A 1O4DA 3MXCA 2HUWA 1O4NA 2RSYA 4F59A 2C0IA 1BLJA 2IUHA 3BUNB 3VRPA 2IUIA 2OZOA 1YVHA 2GSBA 1AOUF 4EIHA 1AYBA 2QMSA 3PSJA 4LUDA 5GJHA 1A07A 1UURA 1OO4A 3IN8A 1CWDL 4H1OA 3N84A 4E93A 1NZLA 3US4A 4FL2A 2CI9A 2B3OA 4F5AA 1O4BA 5DC0B 2EOBA 4GPLB 1R1PA 2DX0A 5EELA 2MK2A 3S8NA 4U1PA 3OB1B 3QWYA 1JWOA 2XP1A 3LYVA 1CJ1A 1O4HA 2Y1NA 2RVFA 1A1AA 1FMKA 4DGPA 1FBZA 2ETZA 2FCIA 1D4WA 2KGYA 1M27A 3WA4A 1A09A 1FU5A 5AXIA 1OPKA 1LCJA 1AYDA 4X6SA 3VRZA 3VS2A 4EY0A 1SHBA 4JE4A 4M4ZA 1SKJA 2VIFA 2L4KA 1B47A 4QSYA 3VS0A 2MC1A 1F1WA 2L3TA 4K45A 1P13A 5CDWA 3PLFB 1GRIA 3VRYA 1MILA 2MRJA 2CRHA 2HCKA 2BBUA 4NWGA 1SPRA 1O4RA 3BUXB 1CSYA 5IBMA 3OV1A 1O4KA 2AOAA 5AULA 1CSZA 3BUMB 1CWEA 1KA6A 1AYAA 1OO3A 1AB2A 2C0OA 1JYRA 1O4OA 4A4BA 1O4GA 1O4LA 2EKXA 2SHPA 4OHIA 1KSWA 3VRNA 1WQUA 2DLZA 4XZ0A 3OB2B 3BUWB 2EO6A 2PLDA 3VGOA 2FO0A 2L6KA 4GL9E 1KC2A 2YU7A 5HKZA 1JYQA 1O48A 3KFJA 2C0TA 2LQWA 5I6VA 2EYZA 1BF5A 2SRCA 1O4CA 4DGXA 1O4PA 5KAZA 3CWGA 1Y57A 3VS6A 2MRKA 2OQ1A 1A1BA 5HKWA 2PLEA 1LUMA 3VRRA 1R1SA 1LUIA 3S8LA 1O49A 1ZFPE 1LKKA 3BKBA 3GXWA 1BHHB 1IJRA 1I3ZA 2H46E 1BKLA 5DC4A 2EYYA 4K44A 2YSXA 5EHPA 2LRAA 3UYOA 3GXXA 1D4TA 1PICA 4XZ1A 3PJPA 1BLKA 3PS5A 1UUSA 4K2RA 2PTKA 4H34A 2MQIA
chains in the Genus database with same CATH topology
1O45A 2Y3AB 1K9AA 4K11A 4P9VA 2Y1MA 1Y1UA 4FL3A 1LCKA 3C7IA 4OHHA 4WWQA 1O4MA 3N8MA 1NRVA 4U17A 4A4CA 2GE9A 2PNBA 1O41A 3MXYA 3BUOB 2K79B 4JEGA 3PFVA 2LNWA 5DF6A 3CXLA 3TKZA 1O46A 2LCTA 3HHMB 4L1BB 3PQZA 3OVEA 2DLYA 2PNAA 1AYCA 1R1QA 4JGHA 3S9KA 1MW4A 3VS5A 1O4QA 2ECDA 3VS4A 2HDXA 3ZNIA 4TZIA 2EYVA 2EO3A 3VS7A 1A1EA 3IMJA 3HIZB 2IZVA 1D1ZA 1O44A 4OHDA 2CIAA 1M61A 3MAZA 3QWXX 2KK6A 3S8OA 1TCEA 1BMBA 4E68A 5EEQA 5EHRA 2CBLA 1LKLA 1AOTF 2DCRA 1JYUA 3NHNA 3IN7A 1O4EA 1JU5A 3GQIB 2RORA 4GWFA 3VROA 2EL8A 4FBNA 1FU6A 1X6CA 2CI8A 1IS0A 4F5BA 1BHFA 4ROJA 1TZEE 1F2FA 1Z3KA 5D0JA 1YVLA 1RJAA 5IBSA 1QG1E 1O42A 1O4JA 3EACA 1BFJA 1KA7A 2AOBA 2ABLA 1A08A 2AUGA 1BM2A 3HCKA 1HCSB 2JYQA 1FYRA 1A81A 3VS1A 1G83A 3PSKA 1SHAA 5J3XA 1BHHA 3OP0A 3T04A 3EAZA 4LUEA 1NZVA 3CBLA 4OHLA 3VS3A 1A1CA 1SPSA 2LNXA 1H9OA 1QADA 3N7YA 1SHDA 2IUGA 1BKMA 4NWFA 5DC9A 3CD3A 2H5KA 1O4IA 2EU0A 2K7AB 1RQQC 4P9ZA 3IMDA 2DM0A 2RMXA 2CR4A 1RPYA 1LUKA 3K2MA 3TL0A 1FHSA 2HDVA 4OHEA 3M7FA 1O47A 1XA6A 5BO4A 5EG3B 3UF4A 3VRQA 1FBVA 1QCFA 1BFIA 5GJIA 2KNOA 2CS0A 2HMHA 1GHUA 1LUNA 2DVJA 1O4FA 1X0NA 2H8HA 1O4AA 1BG1A 1OPLA 1O43A 2C9WA 5HKYA 1HCTB 4D8KA 2LQNA 1AD5A 1X27A 1O4DA 3MXCA 2HUWA 1O4NA 2RSYA 4F59A 2C0IA 1BLJA 2IUHA 3BUNB 3VRPA 2IUIA 2OZOA 1YVHA 2GSBA 1AOUF 4EIHA 1AYBA 2QMSA 3PSJA 4LUDA 5GJHA 1A07A 1UURA 1OO4A 3IN8A 1CWDL 4H1OA 3N84A 4E93A 1NZLA 3US4A 4FL2A 2CI9A 2B3OA 4F5AA 1O4BA 5DC0B 2EOBA 4GPLB 1R1PA 2DX0A 5EELA 2MK2A 3S8NA 4U1PA 3OB1B 3QWYA 1JWOA 2XP1A 1CJ1A 1O4HA 2Y1NA 2RVFA 1A1AA 1FMKA 4DGPA 1FBZA 2ETZA 2FCIA 1D4WA 1M27A 3WA4A 1A09A 1FU5A 5AXIA 1OPKA 1LCJA 1AYDA 4X6SA 3VRZA 3VS2A 4EY0A 1SHBA 4JE4A 4M4ZA 1SKJA 2VIFA 2L4KA 1B47A 4QSYA 3VS0A 2MC1A 1F1WA 2L3TA 4K45A 1P13A 5CDWA 3PLFB 1GRIA 3VRYA 1MILA 2MRJA 2CRHA 2HCKA 2BBUA 4NWGA 1SPRA 1O4RA 3BUXB 1CSYA 5IBMA 3OV1A 1O4KA 2AOAA 5AULA 1CSZA 3BUMB 1CWEA 1KA6A 1AYAA 1OO3A 1AB2A 2C0OA 1JYRA 1O4OA 4A4BA 1O4GA 1O4LA 2EKXA 2SHPA 4OHIA 1KSWA 3VRNA 1WQUA 2DLZA 4XZ0A 3OB2B 3BUWB 2EO6A 2PLDA 3VGOA 2FO0A 2L6KA 4GL9E 1KC2A 2YU7A 5HKZA 1JYQA 1O48A 3KFJA 2C0TA 2LQWA 5I6VA 2EYZA 1BF5A 2SRCA 1O4CA 4DGXA 1O4PA 5KAZA 3CWGA 1Y57A 3VS6A 2MRKA 2OQ1A 1A1BA 5HKWA 2PLEA 1LUMA 3VRRA 1R1SA 1LUIA 3S8LA 1O49A 1ZFPE 1LKKA 3BKBA 3GXWA 1BHHB 1IJRA 1I3ZA 2H46E 1BKLA 5DC4A 2EYYA 4K44A 2YSXA 5EHPA 3UYOA 3GXXA 1D4TA 1PICA 4XZ1A 3PJPA 1BLKA 3PS5A 1UUSA 4K2RA 2PTKA 4H34A 2MQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O45 A;  2Y3A B;  1K9A A;  4K11 A;  4P9V A;  2Y1M A;  1Y1U A;  4FL3 A;  1LCK A;  3C7I A;  4OHH A;  4WWQ A;  1O4M A;  3N8M A;  1NRV A;  4U17 A;  4A4C A;  2GE9 A;  2PNB A;  1O41 A;  3MXY A;  3BUO B;  2K79 B;  4JEG A;  3PFV A;  2LNW A;  5DF6 A;  3CXL A;  3TKZ A;  1O46 A;  2LCT A;  3HHM B;  4L1B B;  3PQZ A;  3OVE A;  2DLY A;  2PNA A;  1AYC A;  1R1Q A;  4JGH A;  3S9K A;  1MW4 A;  3VS5 A;  1O4Q A;  2ECD A;  3VS4 A;  2HDX A;  3ZNI A;  4TZI A;  2EYV A;  2EO3 A;  3VS7 A;  1A1E A;  3IMJ A;  3HIZ B;  2IZV A;  1D1Z A;  1O44 A;  4OHD A;  2CIA A;  1M61 A;  3MAZ A;  3QWX X;  2KK6 A;  3S8O A;  1TCE A;  1BMB A;  4E68 A;  5EEQ A;  5EHR A;  2CBL A;  1LKL A;  1AOT F;  2DCR A;  1JYU A;  3NHN A;  3IN7 A;  1O4E A;  1JU5 A;  3GQI B;  2ROR A;  4GWF A;  3VRO A;  2EL8 A;  4FBN A;  1FU6 A;  1X6C A;  2CI8 A;  1IS0 A;  4F5B A;  1BHF A;  4ROJ A;  1TZE E;  1F2F A;  1Z3K A;  5D0J A;  1YVL A;  1RJA A;  5IBS A;  1QG1 E;  1O42 A;  1O4J A;  3EAC A;  1BFJ A;  1KA7 A;  2AOB A;  2ABL A;  1A08 A;  2AUG A;  1BM2 A;  3HCK A;  1HCS B;  2JYQ A;  1FYR A;  1A81 A;  3VS1 A;  1G83 A;  3PSK A;  1SHA A;  5J3X A;  1BHH A;  3OP0 A;  3T04 A;  3EAZ A;  4LUE A;  1NZV A;  3CBL A;  4OHL A;  3VS3 A;  1A1C A;  1SPS A;  2LNX A;  1H9O A;  1QAD A;  3N7Y A;  1SHD A;  2IUG A;  1BKM A;  4NWF A;  5DC9 A;  3CD3 A;  2H5K A;  1O4I A;  2EU0 A;  2K7A B;  1RQQ C;  4P9Z A;  3IMD A;  2DM0 A;  2RMX A;  2CR4 A;  1RPY A;  1LUK A;  3K2M A;  3TL0 A;  1FHS A;  2HDV A;  4OHE A;  3M7F A;  1O47 A;  1XA6 A;  5BO4 A;  5EG3 B;  3UF4 A;  3VRQ A;  1FBV A;  1QCF A;  1BFI A;  5GJI A;  2KNO A;  2CS0 A;  2HMH A;  1GHU A;  1LUN A;  2DVJ A;  1O4F A;  1X0N A;  2H8H A;  1O4A A;  1BG1 A;  1OPL A;  1O43 A;  2C9W A;  5HKY A;  1HCT B;  4D8K A;  2LQN A;  1AD5 A;  1X27 A;  1O4D A;  3MXC A;  2HUW A;  1O4N A;  2RSY A;  4F59 A;  2C0I A;  1BLJ A;  2IUH A;  3BUN B;  3VRP A;  2IUI A;  2OZO A;  1YVH A;  2GSB A;  1AOU F;  4EIH A;  1AYB A;  2QMS A;  3PSJ A;  4LUD A;  5GJH A;  1A07 A;  1UUR A;  1OO4 A;  3IN8 A;  1CWD L;  4H1O A;  3N84 A;  4E93 A;  1NZL A;  3US4 A;  4FL2 A;  2CI9 A;  2B3O A;  4F5A A;  1O4B A;  5DC0 B;  2EOB A;  4GPL B;  1R1P A;  2DX0 A;  5EEL A;  2MK2 A;  3S8N A;  4U1P A;  3OB1 B;  3QWY A;  1JWO A;  2XP1 A;  1CJ1 A;  1O4H A;  2Y1N A;  2RVF A;  1A1A A;  1FMK A;  4DGP A;  1FBZ A;  2ETZ A;  2FCI A;  1D4W A;  1M27 A;  3WA4 A;  1A09 A;  1FU5 A;  5AXI A;  1OPK A;  1LCJ A;  1AYD A;  4X6S A;  3VRZ A;  3VS2 A;  4EY0 A;  1SHB A;  4JE4 A;  4M4Z A;  1SKJ A;  2VIF A;  2L4K A;  1B47 A;  4QSY A;  3VS0 A;  2MC1 A;  1F1W A;  2L3T A;  4K45 A;  1P13 A;  5CDW A;  3PLF B;  1GRI A;  3VRY A;  1MIL A;  2MRJ A;  2CRH A;  2HCK A;  2BBU A;  4NWG A;  1SPR A;  1O4R A;  3BUX B;  1CSY A;  5IBM A;  3OV1 A;  1O4K A;  2AOA A;  5AUL A;  1CSZ A;  3BUM B;  1CWE A;  1KA6 A;  1AYA A;  1OO3 A;  1AB2 A;  2C0O A;  1JYR A;  1O4O A;  4A4B A;  1O4G A;  1O4L A;  2EKX A;  2SHP A;  4OHI A;  1KSW A;  3VRN A;  1WQU A;  2DLZ A;  4XZ0 A;  3OB2 B;  3BUW B;  2EO6 A;  2PLD A;  3VGO A;  2FO0 A;  2L6K A;  4GL9 E;  1KC2 A;  2YU7 A;  5HKZ A;  1JYQ A;  1O48 A;  3KFJ A;  2C0T A;  2LQW A;  5I6V A;  2EYZ A;  1BF5 A;  2SRC A;  1O4C A;  4DGX A;  1O4P A;  5KAZ A;  3CWG A;  1Y57 A;  3VS6 A;  2MRK A;  2OQ1 A;  1A1B A;  5HKW A;  2PLE A;  1LUM A;  3VRR A;  1R1S A;  1LUI A;  3S8L A;  1O49 A;  1ZFP E;  1LKK A;  3BKB A;  3GXW A;  1BHH B;  1IJR A;  1I3Z A;  2H46 E;  1BKL A;  5DC4 A;  2EYY A;  4K44 A;  2YSX A;  5EHP A;  3UYO A;  3GXX A;  1D4T A;  1PIC A;  4XZ1 A;  3PJP A;  1BLK A;  3PS5 A;  1UUS A;  4K2R A;  2PTK A;  4H34 A;  2MQI A; 
#chains in the Genus database with same CATH topology
 1O45 A;  2Y3A B;  1K9A A;  4K11 A;  4P9V A;  2Y1M A;  1Y1U A;  4FL3 A;  1LCK A;  3C7I A;  4OHH A;  4WWQ A;  1O4M A;  3N8M A;  1NRV A;  4U17 A;  4A4C A;  2GE9 A;  2PNB A;  1O41 A;  3MXY A;  3BUO B;  2K79 B;  4JEG A;  3PFV A;  2LNW A;  5DF6 A;  3CXL A;  3TKZ A;  1O46 A;  2LCT A;  3HHM B;  4L1B B;  3PQZ A;  3OVE A;  2DLY A;  2PNA A;  1AYC A;  1R1Q A;  4JGH A;  3S9K A;  1MW4 A;  3VS5 A;  1O4Q A;  2ECD A;  3VS4 A;  2HDX A;  3ZNI A;  4TZI A;  2EYV A;  2EO3 A;  3VS7 A;  1A1E A;  3IMJ A;  3HIZ B;  2IZV A;  1D1Z A;  1O44 A;  4OHD A;  2CIA A;  1M61 A;  3MAZ A;  3QWX X;  2KK6 A;  3S8O A;  1TCE A;  1BMB A;  4E68 A;  5EEQ A;  5EHR A;  2CBL A;  1LKL A;  1AOT F;  2DCR A;  1JYU A;  3NHN A;  3IN7 A;  1O4E A;  1JU5 A;  3GQI B;  2ROR A;  4GWF A;  3VRO A;  2EL8 A;  4FBN A;  1FU6 A;  1X6C A;  2CI8 A;  1IS0 A;  4F5B A;  1BHF A;  4ROJ A;  1TZE E;  1F2F A;  1Z3K A;  5D0J A;  1YVL A;  1RJA A;  5IBS A;  1QG1 E;  1O42 A;  1O4J A;  3EAC A;  1BFJ A;  1KA7 A;  2AOB A;  2ABL A;  1A08 A;  2AUG A;  1BM2 A;  3HCK A;  1HCS B;  2JYQ A;  1FYR A;  1A81 A;  3VS1 A;  1G83 A;  3PSK A;  1SHA A;  5J3X A;  1BHH A;  3OP0 A;  3T04 A;  3EAZ A;  4LUE A;  1NZV A;  3CBL A;  4OHL A;  3VS3 A;  1A1C A;  1SPS A;  2LNX A;  1H9O A;  1QAD A;  3N7Y A;  1SHD A;  2IUG A;  1BKM A;  4NWF A;  5DC9 A;  3CD3 A;  2H5K A;  1O4I A;  2EU0 A;  2K7A B;  1RQQ C;  4P9Z A;  3IMD A;  2DM0 A;  2RMX A;  2CR4 A;  1RPY A;  1LUK A;  3K2M A;  3TL0 A;  1FHS A;  2HDV A;  4OHE A;  3M7F A;  1O47 A;  1XA6 A;  5BO4 A;  5EG3 B;  3UF4 A;  3VRQ A;  1FBV A;  1QCF A;  3K2T A;  1BFI A;  5GJI A;  2KNO A;  2CS0 A;  2HMH A;  1GHU A;  1LUN A;  2DVJ A;  1O4F A;  1X0N A;  2H8H A;  1O4A A;  1BG1 A;  1OPL A;  1O43 A;  2C9W A;  5HKY A;  1HCT B;  4D8K A;  2LQN A;  1AD5 A;  1X27 A;  1O4D A;  3MXC A;  2HUW A;  1O4N A;  2RSY A;  4F59 A;  2C0I A;  1BLJ A;  2IUH A;  3BUN B;  3VRP A;  2IUI A;  2OZO A;  1YVH A;  2GSB A;  1AOU F;  4EIH A;  1AYB A;  2QMS A;  3PSJ A;  4LUD A;  5GJH A;  1A07 A;  1UUR A;  1OO4 A;  3IN8 A;  1CWD L;  4H1O A;  3N84 A;  4E93 A;  1NZL A;  3US4 A;  4FL2 A;  2CI9 A;  2B3O A;  4F5A A;  1O4B A;  5DC0 B;  2EOB A;  4GPL B;  1R1P A;  2DX0 A;  5EEL A;  2MK2 A;  3S8N A;  4U1P A;  3OB1 B;  3QWY A;  1JWO A;  2XP1 A;  3LYV A;  1CJ1 A;  1O4H A;  2Y1N A;  2RVF A;  1A1A A;  1FMK A;  4DGP A;  1FBZ A;  2ETZ A;  2FCI A;  1D4W A;  2KGY A;  1M27 A;  3WA4 A;  1A09 A;  1FU5 A;  5AXI A;  1OPK A;  1LCJ A;  1AYD A;  4X6S A;  3VRZ A;  3VS2 A;  4EY0 A;  1SHB A;  4JE4 A;  4M4Z A;  1SKJ A;  2VIF A;  2L4K A;  1B47 A;  4QSY A;  3VS0 A;  2MC1 A;  1F1W A;  2L3T A;  4K45 A;  1P13 A;  5CDW A;  3PLF B;  1GRI A;  3VRY A;  1MIL A;  2MRJ A;  2CRH A;  2HCK A;  2BBU A;  4NWG A;  1SPR A;  1O4R A;  3BUX B;  1CSY A;  5IBM A;  3OV1 A;  1O4K A;  2AOA A;  5AUL A;  1CSZ A;  3BUM B;  1CWE A;  1KA6 A;  1AYA A;  1OO3 A;  1AB2 A;  2C0O A;  1JYR A;  1O4O A;  4A4B A;  1O4G A;  1O4L A;  2EKX A;  2SHP A;  4OHI A;  1KSW A;  3VRN A;  1WQU A;  2DLZ A;  4XZ0 A;  3OB2 B;  3BUW B;  2EO6 A;  2PLD A;  3VGO A;  2FO0 A;  2L6K A;  4GL9 E;  1KC2 A;  2YU7 A;  5HKZ A;  1JYQ A;  1O48 A;  3KFJ A;  2C0T A;  2LQW A;  5I6V A;  2EYZ A;  1BF5 A;  2SRC A;  1O4C A;  4DGX A;  1O4P A;  5KAZ A;  3CWG A;  1Y57 A;  3VS6 A;  2MRK A;  2OQ1 A;  1A1B A;  5HKW A;  2PLE A;  1LUM A;  3VRR A;  1R1S A;  1LUI A;  3S8L A;  1O49 A;  1ZFP E;  1LKK A;  3BKB A;  3GXW A;  1BHH B;  1IJR A;  1I3Z A;  2H46 E;  1BKL A;  5DC4 A;  2EYY A;  4K44 A;  2YSX A;  5EHP A;  2LRA A;  3UYO A;  3GXX A;  1D4T A;  1PIC A;  4XZ1 A;  3PJP A;  1BLK A;  3PS5 A;  1UUS A;  4K2R A;  2PTK A;  4H34 A;  2MQI A; 
#chains in the Genus database with same CATH homology
 1O45 A;  2Y3A B;  1K9A A;  4K11 A;  4P9V A;  2Y1M A;  1Y1U A;  4FL3 A;  1LCK A;  3C7I A;  4OHH A;  4WWQ A;  1O4M A;  3N8M A;  1NRV A;  4U17 A;  4A4C A;  2GE9 A;  2PNB A;  1O41 A;  3MXY A;  3BUO B;  2K79 B;  4JEG A;  3PFV A;  2LNW A;  5DF6 A;  3CXL A;  3TKZ A;  1O46 A;  2LCT A;  3HHM B;  4L1B B;  3PQZ A;  3OVE A;  2DLY A;  2PNA A;  1AYC A;  1R1Q A;  4JGH A;  3S9K A;  1MW4 A;  3VS5 A;  1O4Q A;  2ECD A;  3VS4 A;  2HDX A;  3ZNI A;  4TZI A;  2EYV A;  2EO3 A;  3VS7 A;  1A1E A;  3IMJ A;  3HIZ B;  2IZV A;  1D1Z A;  1O44 A;  4OHD A;  2CIA A;  1M61 A;  3MAZ A;  3QWX X;  2KK6 A;  3S8O A;  1TCE A;  1BMB A;  4E68 A;  5EEQ A;  5EHR A;  2CBL A;  1LKL A;  1AOT F;  2DCR A;  1JYU A;  3NHN A;  3IN7 A;  1O4E A;  1JU5 A;  3GQI B;  2ROR A;  4GWF A;  3VRO A;  2EL8 A;  4FBN A;  1FU6 A;  1X6C A;  2CI8 A;  1IS0 A;  4F5B A;  1BHF A;  4ROJ A;  1TZE E;  1F2F A;  1Z3K A;  5D0J A;  1YVL A;  1RJA A;  5IBS A;  1QG1 E;  1O42 A;  1O4J A;  3EAC A;  1BFJ A;  1KA7 A;  2AOB A;  2ABL A;  1A08 A;  2AUG A;  1BM2 A;  3HCK A;  1HCS B;  2JYQ A;  1FYR A;  1A81 A;  3VS1 A;  1G83 A;  3PSK A;  1SHA A;  5J3X A;  1BHH A;  3OP0 A;  3T04 A;  3EAZ A;  4LUE A;  1NZV A;  3CBL A;  4OHL A;  3VS3 A;  1A1C A;  1SPS A;  2LNX A;  1H9O A;  1QAD A;  3N7Y A;  1SHD A;  2IUG A;  1BKM A;  4NWF A;  5DC9 A;  3CD3 A;  2H5K A;  1O4I A;  2EU0 A;  2K7A B;  1RQQ C;  4P9Z A;  3IMD A;  2DM0 A;  2RMX A;  2CR4 A;  1RPY A;  1LUK A;  3K2M A;  3TL0 A;  1FHS A;  2HDV A;  4OHE A;  3M7F A;  1O47 A;  1XA6 A;  5BO4 A;  5EG3 B;  3UF4 A;  3VRQ A;  1FBV A;  1QCF A;  1BFI A;  5GJI A;  2KNO A;  2CS0 A;  2HMH A;  1GHU A;  1LUN A;  2DVJ A;  1O4F A;  1X0N A;  2H8H A;  1O4A A;  1BG1 A;  1OPL A;  1O43 A;  2C9W A;  5HKY A;  1HCT B;  4D8K A;  2LQN A;  1AD5 A;  1X27 A;  1O4D A;  3MXC A;  2HUW A;  1O4N A;  2RSY A;  4F59 A;  2C0I A;  1BLJ A;  2IUH A;  3BUN B;  3VRP A;  2IUI A;  2OZO A;  1YVH A;  2GSB A;  1AOU F;  4EIH A;  1AYB A;  2QMS A;  3PSJ A;  4LUD A;  5GJH A;  1A07 A;  1UUR A;  1OO4 A;  3IN8 A;  1CWD L;  4H1O A;  3N84 A;  4E93 A;  1NZL A;  3US4 A;  4FL2 A;  2CI9 A;  2B3O A;  4F5A A;  1O4B A;  5DC0 B;  2EOB A;  4GPL B;  1R1P A;  2DX0 A;  5EEL A;  2MK2 A;  3S8N A;  4U1P A;  3OB1 B;  3QWY A;  1JWO A;  2XP1 A;  1CJ1 A;  1O4H A;  2Y1N A;  2RVF A;  1A1A A;  1FMK A;  4DGP A;  1FBZ A;  2ETZ A;  2FCI A;  1D4W A;  1M27 A;  3WA4 A;  1A09 A;  1FU5 A;  5AXI A;  1OPK A;  1LCJ A;  1AYD A;  4X6S A;  3VRZ A;  3VS2 A;  4EY0 A;  1SHB A;  4JE4 A;  4M4Z A;  1SKJ A;  2VIF A;  2L4K A;  1B47 A;  4QSY A;  3VS0 A;  2MC1 A;  1F1W A;  2L3T A;  4K45 A;  1P13 A;  5CDW A;  3PLF B;  1GRI A;  3VRY A;  1MIL A;  2MRJ A;  2CRH A;  2HCK A;  2BBU A;  4NWG A;  1SPR A;  1O4R A;  3BUX B;  1CSY A;  5IBM A;  3OV1 A;  1O4K A;  2AOA A;  5AUL A;  1CSZ A;  3BUM B;  1CWE A;  1KA6 A;  1AYA A;  1OO3 A;  1AB2 A;  2C0O A;  1JYR A;  1O4O A;  4A4B A;  1O4G A;  1O4L A;  2EKX A;  2SHP A;  4OHI A;  1KSW A;  3VRN A;  1WQU A;  2DLZ A;  4XZ0 A;  3OB2 B;  3BUW B;  2EO6 A;  2PLD A;  3VGO A;  2FO0 A;  2L6K A;  4GL9 E;  1KC2 A;  2YU7 A;  5HKZ A;  1JYQ A;  1O48 A;  3KFJ A;  2C0T A;  2LQW A;  5I6V A;  2EYZ A;  1BF5 A;  2SRC A;  1O4C A;  4DGX A;  1O4P A;  5KAZ A;  3CWG A;  1Y57 A;  3VS6 A;  2MRK A;  2OQ1 A;  1A1B A;  5HKW A;  2PLE A;  1LUM A;  3VRR A;  1R1S A;  1LUI A;  3S8L A;  1O49 A;  1ZFP E;  1LKK A;  3BKB A;  3GXW A;  1BHH B;  1IJR A;  1I3Z A;  2H46 E;  1BKL A;  5DC4 A;  2EYY A;  4K44 A;  2YSX A;  5EHP A;  3UYO A;  3GXX A;  1D4T A;  1PIC A;  4XZ1 A;  3PJP A;  1BLK A;  3PS5 A;  1UUS A;  4K2R A;  2PTK A;  4H34 A;  2MQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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